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Conserved domains on  [gi|70778904|ref|NP_001020481|]
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alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 isoform 2 precursor [Mus musculus]

Protein Classification

glycosyltransferase family 29 protein( domain architecture ID 690)

glycosyltransferase family 29 protein catalyzes the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds; uses a nucleotide monophosphosugar as the donor (CMP-NeuA) instead of a nucleotide diphosphosugar

CATH:  3.90.1480.20
CAZY:  GT29
EC:  2.4.99.-
Gene Ontology:  GO:0008373|GO:0006486
PubMed:  9334165

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
GT29_ST6GALNAC6 cd23978
alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6; ST6GalNAc family members are ...
 71-298 1.43e-174

alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6; ST6GalNAc family members are alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferases that catalyze an alpha-2,6-linkage between sialic acid and the N-acetylgalactosamine residues of glycochains through an 2,6-linkage, by transfering sialic acid from CMP-Sia. ST6GalNAc3, 4, 5, and 6 utilizeSia2,3Galbeta1,3GalNAc as an acceptor with different individual substrate specificities. The ST6GalNac family belongs to glycosyltransferase family 29 (GT29).


:

Pssm-ID: 467706  Cd Length: 229  Bit Score: 481.66  E-value: 1.43e-174
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70778904  71 CNQCVIITSSSHLLGTKLGPEIERAECTIRMNDAPTSGYSADVGNKTTFRVVAHSSVFRVLRKPQEFVNRTPETVFIFWG 150
Cdd:cd23978   1 CHQCALITSSSHLLGTSLGPEIDQTECTIRMNDAPTTGYEKDVGNKTTLRVVAHSSVYRVLRRPQEFLNRTPETTLIFWG 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70778904 151 PPNKMQKPQGSLL-RVIQRAGLMFPNMEAYAVSPARMQQFDDLFRGETGKDREKSHSWLSTGWFTMVIAVELCDHVHVYG 229
Cdd:cd23978  81 PPNKMQKDGKSNLfRIIQRASMTFPNMSAFVVSPRRMRQFDDLFRGETGRDRKKSHSWLSTGWFTMVIAVELCDNVHVYG 160

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 70778904 230 MVPPDYCSQRPRLQRMPYHYYEPKGPDECVTYIQNEHSRKGNHHRFITEKRVFSSWAQLYGITFSHPSW 298
Cdd:cd23978 161 MVPPNYCSKRPTPKKMPYHYYEPKGPDECVTYIQNEHGRRGNHHRFITEKRVFARWAEHYNITFSHPSW 229
 
Name Accession Description Interval E-value
GT29_ST6GALNAC6 cd23978
alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6; ST6GalNAc family members are ...
 71-298 1.43e-174

alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6; ST6GalNAc family members are alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferases that catalyze an alpha-2,6-linkage between sialic acid and the N-acetylgalactosamine residues of glycochains through an 2,6-linkage, by transfering sialic acid from CMP-Sia. ST6GalNAc3, 4, 5, and 6 utilizeSia2,3Galbeta1,3GalNAc as an acceptor with different individual substrate specificities. The ST6GalNac family belongs to glycosyltransferase family 29 (GT29).


Pssm-ID: 467706  Cd Length: 229  Bit Score: 481.66  E-value: 1.43e-174
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70778904  71 CNQCVIITSSSHLLGTKLGPEIERAECTIRMNDAPTSGYSADVGNKTTFRVVAHSSVFRVLRKPQEFVNRTPETVFIFWG 150
Cdd:cd23978   1 CHQCALITSSSHLLGTSLGPEIDQTECTIRMNDAPTTGYEKDVGNKTTLRVVAHSSVYRVLRRPQEFLNRTPETTLIFWG 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70778904 151 PPNKMQKPQGSLL-RVIQRAGLMFPNMEAYAVSPARMQQFDDLFRGETGKDREKSHSWLSTGWFTMVIAVELCDHVHVYG 229
Cdd:cd23978  81 PPNKMQKDGKSNLfRIIQRASMTFPNMSAFVVSPRRMRQFDDLFRGETGRDRKKSHSWLSTGWFTMVIAVELCDNVHVYG 160

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 70778904 230 MVPPDYCSQRPRLQRMPYHYYEPKGPDECVTYIQNEHSRKGNHHRFITEKRVFSSWAQLYGITFSHPSW 298
Cdd:cd23978 161 MVPPNYCSKRPTPKKMPYHYYEPKGPDECVTYIQNEHGRRGNHHRFITEKRVFARWAEHYNITFSHPSW 229
Glyco_transf_29 pfam00777
Glycosyltransferase family 29 (sialyltransferase); Members of this family belong to ...
 68-251 8.22e-26

Glycosyltransferase family 29 (sialyltransferase); Members of this family belong to glycosyltransferase family 29.


Pssm-ID: 459935  Cd Length: 256  Bit Score: 102.69  E-value: 8.22e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70778904    68 PSRCNQCVIITSSSHLLGTKLGPEIERAECTIRMNDAPTSGYSADVGNKTTFRVV-AHSSVFRVLRKPQEFVNRTPETVF 146
Cdd:pfam00777  40 NKRCRRCAVVGNGGILRGSGCGKEIDSHDFVIRCNLAPTKGYEKDVGSKTTLRTMnPESAIDSKYGNLGFSHPRDPFVEF 119

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70778904   147 IF---------WGPP--NKMQKPQGSL-LRVIQRAGLMFPNMEAYAVSPARMQQFDDLFRGETGKDREKshswLSTGWFT 214
Cdd:pfam00777 120 VLvpfkgrdllWLPAflTKGNVSRSLRvLYTLKEVKIPVDPDKVLFLHPDFLRYVANFWLRSHGLKGRR----PSTGLLM 195

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 70778904   215 MVIAVELCDHVHVYGMVPPDYcsqrprLQRMPYHYYE 251
Cdd:pfam00777 196 LSLALHLCDEVSLYGFGPFLD------SRGNSHHYYD 226
 
Name Accession Description Interval E-value
GT29_ST6GALNAC6 cd23978
alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6; ST6GalNAc family members are ...
 71-298 1.43e-174

alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6; ST6GalNAc family members are alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferases that catalyze an alpha-2,6-linkage between sialic acid and the N-acetylgalactosamine residues of glycochains through an 2,6-linkage, by transfering sialic acid from CMP-Sia. ST6GalNAc3, 4, 5, and 6 utilizeSia2,3Galbeta1,3GalNAc as an acceptor with different individual substrate specificities. The ST6GalNac family belongs to glycosyltransferase family 29 (GT29).


Pssm-ID: 467706  Cd Length: 229  Bit Score: 481.66  E-value: 1.43e-174
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70778904  71 CNQCVIITSSSHLLGTKLGPEIERAECTIRMNDAPTSGYSADVGNKTTFRVVAHSSVFRVLRKPQEFVNRTPETVFIFWG 150
Cdd:cd23978   1 CHQCALITSSSHLLGTSLGPEIDQTECTIRMNDAPTTGYEKDVGNKTTLRVVAHSSVYRVLRRPQEFLNRTPETTLIFWG 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70778904 151 PPNKMQKPQGSLL-RVIQRAGLMFPNMEAYAVSPARMQQFDDLFRGETGKDREKSHSWLSTGWFTMVIAVELCDHVHVYG 229
Cdd:cd23978  81 PPNKMQKDGKSNLfRIIQRASMTFPNMSAFVVSPRRMRQFDDLFRGETGRDRKKSHSWLSTGWFTMVIAVELCDNVHVYG 160

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 70778904 230 MVPPDYCSQRPRLQRMPYHYYEPKGPDECVTYIQNEHSRKGNHHRFITEKRVFSSWAQLYGITFSHPSW 298
Cdd:cd23978 161 MVPPNYCSKRPTPKKMPYHYYEPKGPDECVTYIQNEHGRRGNHHRFITEKRVFARWAEHYNITFSHPSW 229
GT29_ST6GALNAC3_4_5_6 cd23965
alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3, 4, 5 and 6; ST6GalNAc family ...
 71-296 2.02e-124

alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3, 4, 5 and 6; ST6GalNAc family members are alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferases that catalyze an alpha-2,6-linkage between sialic acidand the N-acetylgalactosamine residues of glycochains through an 2,6-linkage, bytransfering sialic acid from CMP-Sia. ST6GalNAc3, 4, 5, and 6 utilizeSia2,3Galbeta1,3GalNAc as an acceptor with different individual substratespecificities. The ST6GalNac family belongs to glycosyltransferase family 29 (GT29).


Pssm-ID: 467693  Cd Length: 225  Bit Score: 354.63  E-value: 2.02e-124
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70778904  71 CNQCVIITSSSHLLGTKLGPEIERAECTIRMNDAPTSGYSADVGNKTTFRVVAHSSVFRVLRKP-QEFVNRTPETVFIFW 149
Cdd:cd23965   1 CDTCALVSSSGQLLGSGAGKEIDSADCVIRMNDAPTRGYEKDVGRRTTIRVVSHSSLPRLLRNAiLLLAGTRAPTVVVFW 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70778904 150 GPPNKMQKPQGSLLRVIQRAGLMFPNMEAYAVSPARMQQFDDLFRGETGKDREKSHSWLSTGWFTMVIAVELCDHVHVYG 229
Cdd:cd23965  81 GPETKMNKDGAGKYNLLRSLSKKYPDVEFYSLTPEKMDYADELFEKETGKSRIKSGTWLSTGWFTMLLALDVCDEIKVYG 160

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 70778904 230 MVPPDYCSQRPRlQRMPYHYYEPKGPDECVTYIQNEHSRKGnHHRFITEKRVFSSWAQLYGITFSHP 296
Cdd:cd23965 161 MVPENYCREHPN-SKVPYHYYEPGGLKECTYYNYHENALKG-GHRFITEKAVFARWAKKYNITFHHP 225
GT29_ST6GALNAC5 cd23976
alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5; ST6GalNAc family members are ...
 58-298 9.81e-109

alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5; ST6GalNAc family members are alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferases that catalyze an alpha-2,6-linkage between sialic acid and the N-acetylgalactosamine residues of glycochains through an 2,6-linkage, by transfering sialic acid from CMP-Sia. ST6GalNAc3, 4, 5, and 6 utilize Sia2,3Galbeta1,3GalNAc as an acceptor with different individual substrate specificities. The ST6GalNac family belongs to glycosyltransferase family 29 (GT29).


Pssm-ID: 467704  Cd Length: 244  Bit Score: 315.65  E-value: 9.81e-109
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70778904  58 YFPILGNKTLPSRCNQCVIITSSSHLLGTKLGPEIERAECTIRMNDAPTSGYSADVGNKTTFRVVAHSSVFRVLRKPQEF 137
Cdd:cd23976   2 YISIIDHKPLKMHCKSCALVTSSGHLTGSNRGNEIDETECVIRMNDAPTRGYGKDVGNKTSLRVIAHSSIQRILRNRNEL 81

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70778904 138 VNRTPETVFIFWGPPNKMQKP-QGSLLRVIQRAGLMFPNMEAYAVSPARMQQFDDLFRGETGKDREKSHSWLSTGWFTMV 216
Cdd:cd23976  82 LNVSQGTVFIFWGPSNYMRRDgKGLVYNNLQLMNQILPKLKVYTITRHKMLQFDELFKRETGKDRKISNTWLSTGWFTMI 161

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70778904 217 IAVELCDHVHVYGMVPPDYCsQRPRLQRMPYHYYEPKGPDECVTYIQNEHSRKGNHHRFITEKRVFSSWAQLYGITFSHP 296
Cdd:cd23976 162 IALELCDRINVYGMVPPDFC-RDPNHPSVPYHYYEPSGPDECTMYISHERGRKGSHHRFITEKRVFANWARTFNIHFYQP 240


                ..
gi 70778904 297 SW 298
Cdd:cd23976 241 DW 242
GT29_ST6GALNAC4 cd23977
alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4; ST6GalNAc family members are ...
 71-299 6.75e-86

alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4; ST6GalNAc family members are alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferases that catalyze an alpha-2,6-linkage between sialic acid and the N-acetylgalactosamine residues of glycochains through an 2,6-linkage, by transfering sialic acid from CMP-Sia. ST6GalNAc3, 4, 5, and 6 utilizeSia2,3Galbeta1,3GalNAc as an acceptor with different individual substrate specificities. The ST6GalNac family belongs to glycosyltransferase family 29 (GT29).


Pssm-ID: 467705  Cd Length: 228  Bit Score: 257.10  E-value: 6.75e-86
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70778904  71 CNQCVIITSSSHLLGTKLGPEIERAECTIRMNDAPTSGYSADVGNKTTFRVVAHSSVFRVLRKPQEFVNRTPETVFIFWG 150
Cdd:cd23977   1 CRRCAVVSSSGQMLGSGLGPEIDQQECVLRMNVAPTAGYEADVGNRSSLRVVSHTSVPLLLRNQGYFFQQSRDTKYVIWG 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70778904 151 PPNKM-QKPQGSLLRVIQRAGLMFPNMEAYAVSPARMQQFDDLFRGETGKDREKSHSWLSTGWFTMVIAVELCDHVHVYG 229
Cdd:cd23977  81 PERNMdRDGGGKTYRALLTLAKMYPHLQVYTLTEEKMAYCDGVFQNETGKNRMKSGSFLSTGWFTMILALELCEEILVYG 160

                       170       180       190       200       210       220       230
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70778904 230 MVPPDYCSQRPRlQRMPYHYYEPKGPDECVTYIQNEHSRKGNhHRFITEKRVFSSWAQLYGITFSHPSWT 299
Cdd:cd23977 161 MVSDSYCRNKNH-SSVPYHYYEKGRLDECRMYLVHERAPRGG-HRFITEKAIFSRWAKRKKIRFAHPSWT 228
GT29_ST6GALNAC3 cd23975
alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3; ST6GalNAc family members are ...
 71-298 3.07e-79

alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3; ST6GalNAc family members are alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferases that catalyze an alpha-2,6-linkage between sialic acid and the N-acetylgalactosamine residues of glycochains through an 2,6-linkage, by transfering sialic acid from CMP-Sia. ST6GalNAc3, 4, 5, and 6 utilizeSia2,3Galbeta1,3GalNAc as an acceptor with different individual substrate specificities. The ST6GalNac family belongs to glycosyltransferase family 29 (GT29).


Pssm-ID: 467703  Cd Length: 226  Bit Score: 239.83  E-value: 3.07e-79
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70778904  71 CNQCVIITSSSHLLGTKLGPEIERAECTIRMNDAPTSGYSADVGNKTTFRVVAHSSVFRVLRKPQEFVNRTPETVFIFWG 150
Cdd:cd23975   1 CDLCAVVSNSGQMVGQKVGAEIDQSSCIWRMNNAPTKGYEEDVGKRTTIRVVSHTSVPLLLKNPDYFFKETNETIYVIWG 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70778904 151 PPNKMQKP-QGSLLRVIQRAGLMFPNMEAYAVSPARMQQFDDLFRGETGKDREKSHSWLSTGWFTMVIAVELCDHVHVYG 229
Cdd:cd23975  81 PFRNMRKDgKGIVYNMLKKAVESYPQAKIYVTTEKRMSYCDTVFKKETGKDRVQSGSYLSTGWFTLILAMDACYGIHVYG 160

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 70778904 230 MVPPDYCSQRPrLQRMPYHYYEPkGPDECVTYIQNEHSRKGNhHRFITEKRVFSSWAQLYGITFSHPSW 298
Cdd:cd23975 161 MINDTYCKTEG-YRKVPYHYYEP-GRDECDEYFLHENAPYGG-HRFITEKKVFAKWAKKHPITFTHPNW 226
GT29 cd19952
glycosyltransferase family 29; Glycosyltransferase family 29 members (also called ...
 74-285 3.69e-35

glycosyltransferase family 29; Glycosyltransferase family 29 members (also called sialyltransferases) are enzymes that transfer sialic acid to oligosaccharide, each having specificity for a certain sugar substrate.


Pssm-ID: 467690  Cd Length: 193  Bit Score: 125.55  E-value: 3.69e-35
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70778904  74 CVIITSSSHLLGTKLGPEIERAECTIRMNDAPTSGYSADVGNKTTFRVVAHSSVFRVLRKPQEFVNRTP---ETVFIFWG 150
Cdd:cd19952   1 CAVVGNSGILLGSEYGKEIDSHDAVFRFNQAPTKGFEKDVGSKTTFRVLNSKWAGFYLRGPRCGCHPLPleeEVVLILSR 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70778904 151 PPNKMQKpqgsllRVIQRAGLmfPNMEAYAVSPAR---MQQFDDLFRGETGKDrEKSHSWLSTGWFTMVIAVELCDHVHV 227
Cdd:cd19952  81 AAAADFK------RLKRRKKR--HDNAVLLLTDPApdlLSYVRKRLEKLGLKS-FFGGNAPSSGLLAVLLALQLCDSVDL 151

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|
gi 70778904 228 YGM--VPPDYCSQrprlqrmPYHYYEPKGPdecvtyiqnehSRKGNHHRFITEKRVFSSW 285
Cdd:cd19952 152 YGFgvDSGHAPKV-------PYHYYDLVEA-----------EEGTAVHSFDLEAELLRAL 193
Glyco_transf_29 pfam00777
Glycosyltransferase family 29 (sialyltransferase); Members of this family belong to ...
 68-251 8.22e-26

Glycosyltransferase family 29 (sialyltransferase); Members of this family belong to glycosyltransferase family 29.


Pssm-ID: 459935  Cd Length: 256  Bit Score: 102.69  E-value: 8.22e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70778904    68 PSRCNQCVIITSSSHLLGTKLGPEIERAECTIRMNDAPTSGYSADVGNKTTFRVV-AHSSVFRVLRKPQEFVNRTPETVF 146
Cdd:pfam00777  40 NKRCRRCAVVGNGGILRGSGCGKEIDSHDFVIRCNLAPTKGYEKDVGSKTTLRTMnPESAIDSKYGNLGFSHPRDPFVEF 119

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70778904   147 IF---------WGPP--NKMQKPQGSL-LRVIQRAGLMFPNMEAYAVSPARMQQFDDLFRGETGKDREKshswLSTGWFT 214
Cdd:pfam00777 120 VLvpfkgrdllWLPAflTKGNVSRSLRvLYTLKEVKIPVDPDKVLFLHPDFLRYVANFWLRSHGLKGRR----PSTGLLM 195

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 70778904   215 MVIAVELCDHVHVYGMVPPDYcsqrprLQRMPYHYYE 251
Cdd:pfam00777 196 LSLALHLCDEVSLYGFGPFLD------SRGNSHHYYD 226
GT29_ST3GAL3_4_5_6 cd23967
beta-galactoside alpha-2,3-sialyltransferase 3,4,5 and 6; ST3GAL family transfers sialic acid ...
 70-253 2.96e-25

beta-galactoside alpha-2,3-sialyltransferase 3,4,5 and 6; ST3GAL family transfers sialic acid from CMP-Sia to the terminalgalactose residues of glycochains through an 2,3-linkage. ST3GAL3 and 4 utilize bothGalbeta1,3GlcNAc and Galbeta1,4GlcNAc, mainly on glycoproteins and oligosaccharidesas acceptor substrates. ST3GAL5 is also known as GM3 ganglioside synthase. ST3GAL6 utilizes the Galbeta1,4GlcNAc on glycoproteins and glycolipids as an acceptor. Members of this family belong to glycosyltransferase family 29 (GT29).


Pssm-ID: 467695  Cd Length: 205  Bit Score: 100.06  E-value: 2.96e-25
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70778904  70 RCNQCVIITSSSHLLGTKLGPEIERAECTIRMNDAPTSGYSADVGNKTTFRVVAHSSVFrvlRKPQEFvnrTPETVFIFw 149
Cdd:cd23967   1 SCRRCVVVGNGGVLKGKSLGSVIDKYDVVIRMNDAPVKGYEKDVGSKTTFRMFYPESAF---RDPEEY---DSDWLLVL- 73

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70778904 150 gppnKMQKPQGS--LLRVIQ------RAGLMFPNMEAYAVSPARMQQFDDLFRGETG-------KDREKSHSWLSTGWFT 214
Cdd:cd23967  74 ----VPFKSMDLlwLQAVIKgkkpngKGGFWKKIATSVPKPPKKIRILNPYILQEAAfdliglpMNGKQGKNVPTTGIIA 149

                       170       180       190       200
                ....*....|....*....|....*....|....*....|...
gi 70778904 215 MVIAVELCDHVHV----YGMVPPDycsqrprlqrMPYHYYEPK 253
Cdd:cd23967 150 IVMALHYCDEVDIagfgYDPSDPN----------APLHYYDSL 182
GT29_ST6GAL1_2 cd23968
beta-galactoside alpha-2,6-sialyltransferase 1 and 2; ST6Gal family members are ...
 38-252 1.14e-21

beta-galactoside alpha-2,6-sialyltransferase 1 and 2; ST6Gal family members are beta-galactosidealpha-2,6-sialyltransferases that catalyze an alpha-2,6-linkage between sialic acidand the terminal galactose residue of a glycochain, by transfering sialic acid fromCMP-Sia. The ST6Gal family belongs to the glycosyltransferase family 29 (GT29).


Pssm-ID: 467696  Cd Length: 266  Bit Score: 91.95  E-value: 1.14e-21
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70778904  38 SLRGRTRRPVNLKKWSfssaYFPILGNKTLPSRC-NQCVIITSSSHLLGTKLGPEIERAECTIRMNDAPTSGYSADVGNK 116
Cdd:cd23968  15 STLRKTTSPFKDLLSL----RYPFPESSLENTKRyNTCAVVSSSGALLGSKLGKEIDSHDAVLRFNDAPTKGFEKDVGSK 90

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70778904 117 TTFRVVAH----SSVFRVLRKPqEFVNrtpETVFIfWGP-------PNKMQKPQGSLLRVIQRAGLMFPNMEAYAVSPAR 185
Cdd:cd23968  91 TTLRLINSqilsKPEFNFLTDP-LYRN---VTLLV-WDPssynvnlEKWYKKPDFDFFPNYIKYRRRHPEEPFYLIDPRF 165

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 70778904 186 M-QQFDDLFRGETGKDREKSHswlSTGWFTMVIAVELCDHVHVYGMVPPdycSQRPRLQrmpyHYYEP 252
Cdd:cd23968 166 LwRLWDILQEYTPEKIKPNPP---SSGFIGIVLMLHLCDWVDVYEYVPS---VRQTDRC----HYYDV 223
GT29_ST8SIA cd23963
alpha-N-acetylneuraminide alpha-2,8-sialyltransferase; ST8Sia family members are ...
 83-278 1.05e-20

alpha-N-acetylneuraminide alpha-2,8-sialyltransferase; ST8Sia family members are alpha-N-acetylneuraminidealpha-2,8-sialyltransferases that catalyze an alpha-2,8-linkage between sialic acid and the terminal sialic acid residues of glycochains, by transfering sialic acid from CMP-Sia. The family is subdivided into 3 classes of enzymes, depending on their catalytic activiy, the mono-STs (ST8Sia1, ST8Sia5 and ST8Sia6), the oligo-ST(ST8Sia3), and the poly-STs (ST8Sia2 and ST8Sia4). The ST8Sia family belongs to glycosyltransferase family 29 (GT29).


Pssm-ID: 467691  Cd Length: 274  Bit Score: 89.24  E-value: 1.05e-20
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70778904  83 LLGTKLGPEIERAECTIRMNDAPTSGYSADVGNKTTFRVVAHSSVFRVL------RKPQEFVNRTPETV-FIFWGPPNKM 155
Cdd:cd23963  75 LLGSGCGKEIDSHDFVIRCNLPPIKGFEKDVGRKTNLTTLNPSILKRRYnslkknRDRDKFLNRLKEYNgSILWYPKFSF 154

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70778904 156 QKPQGSLLRVIQRAGLMFPNME---AYAVSPARMQQfddlFRGETGKDRekshsWLSTGWFTMVIAVELCDHVHVYGMVP 232
Cdd:cd23963 155 KSSTNLLLKAARALKKNGLNLTvvySNPEHFLAVQK----FWKRRGLEK-----RPSTGLYLVSLALTFCDEIHLYGFWP 225

                       170       180       190       200
                ....*....|....*....|....*....|....*....|....*.
gi 70778904 233 pdYcSQRPRLQRMPYHYYEPkgpdecvtyiqNEHSRKGNHHRFITE 278
Cdd:cd23963 226 --F-PTDPNGRPVPYHYYDD-----------LSPSTKNKVHNMPEE 257
GT29_ST6GAL1 cd23985
beta-galactoside alpha-2,6-sialyltransferase 1; ST6Gal family members are beta-galactoside ...
 46-251 1.41e-18

beta-galactoside alpha-2,6-sialyltransferase 1; ST6Gal family members are beta-galactoside alpha-2,6-sialyltransferases that catalyze an alpha-2,6-linkage between sialic acid and the terminal galactose residue of a glycochain, by transfering sialic acid from CMP-Sia. ST6Gal1 play important roles in the immune system. The ST6Gal family belongs to the glycosyltransferase family 29 (GT29).


Pssm-ID: 467713  Cd Length: 266  Bit Score: 83.22  E-value: 1.41e-18
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70778904  46 PVNLKKWSfssAYFPilgNKTLPSRCNQ---CVIITSSSHLLGTKLGPEIERAECTIRMNDAPTSGYSADVGNKTTFRVV 122
Cdd:cd23985  23 PFNTSEWE---GYLP---KKSLREEVGPlgrCAVVSSAGSLKSSGLGREIDSHDAVLRFNGAPTAGFQQDVGTKTTIRLI 96

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70778904 123 aHSSVfrVLRKPQEFVNRT--PETVFIFWGP-------PNKMQKPQGSLLRVIQRAGLMFPNMEAYAVSPaRMQ-QFDDL 192
Cdd:cd23985  97 -NSQL--VTTEKHKFLKDSlyNEGILIVWDPapyhsdiPEWYKNPDYNFFENYKTYRRLNPNQPFYILHP-QMQwELWDI 172

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|....*....
gi 70778904 193 FRGETGKDREKSHSwlSTGWFTMVIAVELCDHVHVYGMVPpdycSQRprlQRMPYHYYE 251
Cdd:cd23985 173 IQENSPEEIQPNPP--SSGMLGIILMMTLCDQVDVYEFLP----SKR---KTDVCHYYQ 222
GT29_ST6GAL2 cd23986
beta-galactoside alpha-2,6-sialyltransferase 2; ST6Gal family members are beta-galactoside ...
 39-251 3.99e-18

beta-galactoside alpha-2,6-sialyltransferase 2; ST6Gal family members are beta-galactoside alpha-2,3-sialyltransferases that catalyze an alpha2,6-linkage between sialic acid and the terminal galactose residue of a glycochain, by a transfering sialic acid from CMP-Sia. Members of this family belong to glycosyltransferase family 29 (GT29).


Pssm-ID: 467714  Cd Length: 270  Bit Score: 82.19  E-value: 3.99e-18
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70778904  39 LRGRTR-RPVNLKKWSFSS----AYFP-ILGNKTLPSRCNQCVIITSSSHLLGTKLGPEIERAECTIRMNDAPTSGYSAD 112
Cdd:cd23986  11 LKKRVQvRTLDGKEAPFSAlgweKYVPkIPLSKLHLRGFRSCAVVTSAGAILNSSLGKEIDSHDAVLRFNSAPTRGYEKD 90

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70778904 113 VGNKTTFRVVAHssvfRVLRKPQEFVNRTP---ETVFIFWGPP-------NKMQKPQGSLLRVIQRAGLMFPNMEAYAVS 182
Cdd:cd23986  91 VGNKTTIRIINS----QILTNPNHHFIDSSlykDVILVAWDPApysanlhKWYKKPDYNLFTPYVQYRKRNPNQPFYILH 166

                       170       180       190       200       210       220       230
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 70778904 183 PARMQQFDDLFRGETGKDREKSHSwlSTGWFTMVIAVELCDHVHVYGMVPP----DYCsqrprlqrmpyHYYE 251
Cdd:cd23986 167 PKFIWQLWDIIQENTQEKIQPNPP--SSGFIGILIMMSMCREVHVYEYIPSvrqtDLC-----------HYHE 226
GT29_ST3GAL4 cd23982
beta-galactoside alpha-2,3-sialyltransferase 4; ST3GAL family transfers sialic acid from ...
 70-251 5.48e-15

beta-galactoside alpha-2,3-sialyltransferase 4; ST3GAL family transfers sialic acid from CMP-Sia to the terminal galactose residues of glycochains through an 2,3-linkage. ST3GAL4 can utilize both Galbeta1,3GlcNAc and Galbeta1,4GlcNAc, mainly on glycoproteins and oligosaccharidesas acceptor substrates, but prefers the Galbeta1,4GlcNAc. Members of this family belong to glycosyltransferase family 29 (GT29).


Pssm-ID: 467710  Cd Length: 204  Bit Score: 72.00  E-value: 5.48e-15
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70778904  70 RCNQCVIITSSSHLLGTKLGPEIERAECTIRMNDAPTSGYSADVGNKTTFRVV----AHSS-----------VFrVLRKP 134
Cdd:cd23982   1 RCRRCVVVGNGHNLKNSSLGDVIDSYDVVIRLNDAPVRGFEKDVGSKTTIRLFypesAQFDpgiendpdtllVL-VPFKP 79

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70778904 135 QEF------VNRTPETVFIFWGPPNKMQKPQGSLLRVIqraglmfpnmeayavSPARMQQFDDLFRGETGKDREKSHSwl 208
Cdd:cd23982  80 LDFywlyeiLSNEKRVRKGFWKQPPRIWDANPKQIRIL---------------NPYYTYVAATKLLQVPGQRKKKQKP-- 142

                       170       180       190       200
                ....*....|....*....|....*....|....*....|...
gi 70778904 209 STGWFTMVIAVELCDHVHVYGMVPPDycsqrPRLQRMPYHYYE 251
Cdd:cd23982 143 TTGLLAITLALHLCDEVHIAGFGYPD-----NGNSNQPIHYYN 180
GT29_ST3GAL5 cd23983
beta-galactoside alpha-2,3-sialyltransferase 5; ST3GAL family transfers sialic acid from ...
 71-251 4.22e-13

beta-galactoside alpha-2,3-sialyltransferase 5; ST3GAL family transfers sialic acid from CMP-Sia to the terminalgalactose residues of glycochains through an 2,3-linkage. ST3GAL5 is also known as GM3 ganglioside synthase. Members of this family belong to glycosyltransferase family 29 (GT29).


Pssm-ID: 467711  Cd Length: 211  Bit Score: 67.07  E-value: 4.22e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70778904  71 CNQCVIITSSSHLLGTKLGPEIERAECTIRMNDAPTSGYSADVGNKTTFRVV------------AHSSVF-RVLRKPQEF 137
Cdd:cd23983   2 CRRCVVVGSGGILHGLELGHLLDQFDIVIRLNNAPVQGYSQDVGNKTTIRMTypegapkseqeyDPTSLFvAVLFKSVDF 81

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70778904 138 ------VNRTPETV---FIFWGPPNKMQKPQGSLLRV-----IQRAGLmfpNMEAYAVSPARMQQFDdlfrgetgkdreK 203
Cdd:cd23983  82 awlkamVKKEPLSFwsrLFFWKEVADSIPLKPSQFRIlnpliIKETAL---DILQYPEPQSRLWGWD------------K 146

                       170       180       190       200
                ....*....|....*....|....*....|....*....|....*...
gi 70778904 204 SHSWLstGWFTMVIAVELCDHVHVYGMvppDYCSQRPRLqrmPYHYYE 251
Cdd:cd23983 147 NVPTL--GVTAVVLATHLCDEVSLAGF---GYDLSQPHA---PLHYYD 186
GT29_ST8SIA_poly cd23969
alpha-N-acetylneuraminide alpha-2,8-sialyltransferase 2 and 4; ST8Sia2 and 4 are known to be ...
 70-254 7.30e-13

alpha-N-acetylneuraminide alpha-2,8-sialyltransferase 2 and 4; ST8Sia2 and 4 are known to be polysialyltransferases, and they can synthesize polysialic acid on neural cell adhesion molecules (NCAMs). ST8Sia family members are alpha-N-acetylneuraminide alpha-2,8-sialyltransferases that catalyze an alpha-2,8-linkage between sialic acid and the terminal sialic acid residues of glycochains, by transfering sialic acid from CMP-Sia and they belong to the glycosyltransferase family 29 (GT29).


Pssm-ID: 467697  Cd Length: 276  Bit Score: 67.44  E-value: 7.30e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70778904  70 RCNQCVIITSSSHLLGTKLGPEIERAECTIRMNDAPTSGYSADVGNKTTFrVVAHSSVfrVLRKPQEFVNRTPETVFIfw 149
Cdd:cd23969  63 HFRTCAVVGNSGILLNSGCGQEIDSHDFVIRCNLAPVEGYEKDVGTKSNL-TTMNPSV--IPHAYGDLVNATDKEKFV-- 137

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70778904 150 gppNKMQKPQGSLLRViqrAGLMFPNMEAY-----------------AVSPARMQQfddLFRG--ETGKDREKSHswlST 210
Cdd:cd23969 138 ---ERLRQLGDSILWI---PAFVSKGGEEHvqwtneiilkhklnvktAYPPLRLNH---AIRGywLTTKFRIKRP---ST 205

                       170       180       190       200
                ....*....|....*....|....*....|....*....|....
gi 70778904 211 GWFTMVIAVELCDHVHVYGMVPpdyCSQRPRLQRMPYHYYEPKG 254
Cdd:cd23969 206 GLLMYTLATRFCDEIHLYGFYP---FSEDGNGRAVKYHYYDNRK 246
GT29_ST8SIA3_oligo cd23970
alpha-N-acetylneuraminide alpha-2,8-sialyltransferase 3; Alpha-N-acetylneuraminide alpha-2, ...
 72-254 2.95e-12

alpha-N-acetylneuraminide alpha-2,8-sialyltransferase 3; Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase 3 synthesizes polysialic acid and has been shown to autopolysialylate. ST8Sia3 utilizes the Siaalpha2,3Galbeta1,4GlcNAc structure on N-glycans of glycoproteins and glycolipids as acceptor substrates. ST8Sia family members are alpha-N-acetylneuraminidealpha-2,8-sialyltransferases that catalyze an alpha-2,8-linkage between sialic acidand the terminal sialic acid residues of glycochains, by transfering sialic acidfrom CMP-Sia and they belong to glycosyltransferase family 29 (GT29).


Pssm-ID: 467698  Cd Length: 284  Bit Score: 65.49  E-value: 2.95e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70778904  72 NQCVIITSSSHLLGTKLGPEIERAECTIRMNDAPTSGYSADVGNKT---TFR-------------VVAHSSVFRVLRK-- 133
Cdd:cd23970  69 NTCAVVGNSGILTNSQCGNEIDKSDFVFRCNFAPTEGFEKDVGRKTnltTFNpsilekyynnlltIQDRNNFFLSLKKld 148

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70778904 134 ------PQEF------VNRTPETVFI-FWGPPNkmqkpqgsllrvIQragLMFP-NMeayavsparMQQFDDLFRGETGK 199
Cdd:cd23970 149 gailwiPAFFfhtsatVTRTLVDFFVeHRGQLK------------VQ---LAWPgNI---------MQHVNRYWKTKHLS 204

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|....*.
gi 70778904 200 DREkshswLSTGWFTMVIAVELCDHVHVYGMVP-PDYCSQRPrlqrMPYHYYEPKG 254
Cdd:cd23970 205 PKR-----LSTGILMYTLASAICEEIHLYGFWPfGFDPTGTP----LPYHYYDKKG 251
GT29_ST3GAL6 cd23984
beta-galactoside alpha-2,3-sialyltransferase 6; ST3GAL family transfers sialic acid from ...
 71-251 9.90e-12

beta-galactoside alpha-2,3-sialyltransferase 6; ST3GAL family transfers sialic acid from CMP-Sia to the terminal galactose residues of glycochains through an 2,3-linkage. ST3GAL6 utilizes the Galbeta1,4GlcNAc on glycoproteins and glycolipids as an acceptor. Members of this family belong to glycosyltransferase family 29 (GT29).


Pssm-ID: 467712  Cd Length: 206  Bit Score: 62.84  E-value: 9.90e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70778904  71 CNQCVIITSSSHLLGTKLGPEIERAECTIRMNDAPTSGYSADVGNKTTFRVVAHSSVFR-------------VLRKPQ-- 135
Cdd:cd23984   2 CKKCVVVGNGGVLRNKSLGKKIDSYDVIIRMNNGPVIGYENDVGKRTTFRLCYPESIFSdpshydpnttvvlIPFKPHdl 81

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70778904 136 ----EFVNRTPETVFIFW-GPPNKMQ-KP-QGSLL--RVIQRAGLMFPNMeayavsPARmqqFDdlfrgetgKDREKSHS 206
Cdd:cd23984  82 rwllDLLMGKKVSAKGFWkKPALNLIyKPnQIRILnpFILRIAAYELLHF------PKR---FP--------KEKKPKHP 144

                       170       180       190       200
                ....*....|....*....|....*....|....*....|....*..
gi 70778904 207 wlSTGWFTMVIAVELCDHVHVYGMvppdycsqRPRLQRM--PYHYYE 251
Cdd:cd23984 145 --TTGIIAITLALHICNEVHIAGF--------KYDFSNLnsTLHYYG 181
GT29_ST3GAL1_2 cd23966
beta-galactoside alpha-2,3-sialyltransferase 1 and 2; ST3GAL family transfer sialic acid from ...
 68-230 2.05e-11

beta-galactoside alpha-2,3-sialyltransferase 1 and 2; ST3GAL family transfer sialic acid from CMP-Sia to the terminalgalactose residues of glycochains through an 2,3-linkage. ST3GAL1 and 2 preferentially utilize the Galbeta1,3GalNAc on O-glycans of glycoproteins (core1O-glycans) and on glycolipids as an acceptor substrate, respectively. Members ofthis family belong to glycosyltransferase family 29.


Pssm-ID: 467694  Cd Length: 276  Bit Score: 63.07  E-value: 2.05e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70778904  68 PSRCNQCVIITSSSHLLGTKLGPEIERAECTIRMNDAPTSGYSADVGNKTTFRVVAhssvfrvlrkPQEFVNRTPETVFI 147
Cdd:cd23966  74 PNRCRRCAVVGNSGNLRGSRYGKLIDSHDFVIRMNKAPTKGFEKDVGSKTTHHFMY----------PESAVDLDPGVHLV 143

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70778904 148 ---FwgppnkmqKPQGsllrvIQRAGLMFPNMEAyAVSPARMQQFDDLfrgetgkDREK-----------SH-SWL---- 208
Cdd:cd23966 144 lvpF--------KVLD-----LQWLISALTTGEI-TRTYTPVKRFIKA-------DKDKvlvinpafikyVHdNWTehhg 202

                       170       180
                ....*....|....*....|....*
gi 70778904 209 ---STGWFTMVIAVELCDHVHVYGM 230
Cdd:cd23966 203 rypSTGFLALIFALHICDEVSVFGF 227
GT29_ST3GAL1 cd23980
beta-galactoside alpha-2,3-sialyltransferase 1; ST3GAL family transfer sialic acid from ...
 68-229 1.01e-10

beta-galactoside alpha-2,3-sialyltransferase 1; ST3GAL family transfer sialic acid from CMP-Sia to the terminal galactose residues of glycochains through an 2,3-linkage. ST3GAL1 preferentially utilizes the Galbeta1,3GalNAc on O-glycans of glycoproteins (core1 O-glycans) as an acceptor substrate. Members of this family belong to glycosyltransferase family29 (GT29).


Pssm-ID: 467708  Cd Length: 280  Bit Score: 61.05  E-value: 1.01e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70778904  68 PSRCNQCVIITSSSHLLGTKLGPEIERAECTIRMNDAPTSGYSADVGNKTTFRVVAHSSvFRVLRKPQEFVNRTPETVFI 147
Cdd:cd23980  78 LVSCRRCAVVGNSGNLKESYYGPQIDSHDFVLRMNKAPTEGFEADVGSKTTHHFVYPES-FRELAQNVSMILVPFKTLDL 156

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70778904 148 FW-------GPPNKMQKPQGSLLRVIQRAGLMFpnmeayavSPARMQQFDDLFRGETGKdrekshsWLSTGWFTMVIAVE 220
Cdd:cd23980 157 EWvisatttGTISHTYVPVPRKIKVKKEKILIY--------HPAFIKYVFDRWLQGHGR-------YPSTGILSVIFSLH 221


                ....*....
gi 70778904 221 LCDHVHVYG 229
Cdd:cd23980 222 VCDEVDLYG 230
GT29_ST8SIA2 cd23987
alpha-N-acetylneuraminide alpha-2,8-sialyltransferase 2; ST8Sia2 is a polysialyltransferase ...
 62-251 1.52e-10

alpha-N-acetylneuraminide alpha-2,8-sialyltransferase 2; ST8Sia2 is a polysialyltransferase that can synthesize polysialic acid on neural cell adhesion molecules (NCAMs). ST8Sia2 catalyzes shorter polysialic acid formation of NCAMs than ST8Sia4. ST8Sia family members are alpha-N-acetylneuraminide alpha-2,8-sialyltransferases that catalyze an alpha-2,8-linkage between sialic acid and the terminal sialic acid residues of glycochains, by transfering sialic acid from CMP-Sia and they belong to the glycosyltransferase family 29 (GT29).


Pssm-ID: 467715  Cd Length: 278  Bit Score: 60.72  E-value: 1.52e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70778904  62 LGNKTLPSrcnqCVIITSSSHLLGTKLGPEIERAECTIRMNDAPTSGYSADVGNKTTFrVVAHSSVfrVLRKPQEFVNRT 141
Cdd:cd23987  59 LKNKHFKT----CAIVGNSGILLNSGCGREIDSHDFVIRCNLAPVEEYAKDVGTKTDL-VTMNPSV--VQRAFEDLVNET 131

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70778904 142 PETVFIfwgppNKMQKPQGSLLRViqraglmfPNMEAYAvSPARMQQFDDLFRGETGKDREKSHS----------WL--- 208
Cdd:cd23987 132 WKEKFL-----QRLQSLNGSILWI--------PAFMAKG-GEERVEWVNDLILKHHINVRTAYPSlrllhavrgyWLtnk 197

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|
gi 70778904 209 ------STGWFTMVIAVELCDHVHVYGMVP-PDYCSQRPrlqrMPYHYYE 251
Cdd:cd23987 198 vhikrpTTGLLMYTLATRFCNRIHLYGFWPfPRDQNQNP----VKYHYYD 243
GT29_ST8SIA_mono cd23971
alpha-N-acetylneuraminide alpha-2,8-sialyltransferase 1, 5 and 6; ST8 Sia family members are ...
 72-255 2.03e-10

alpha-N-acetylneuraminide alpha-2,8-sialyltransferase 1, 5 and 6; ST8 Sia family members are alpha-N-acetylneuraminidealpha-2,8-sialyltransferases that catalyze an alpha-2,8-linkage between sialic acid and the terminal sialic acid residues of glycochains, by transfering sialic acid from CMP-Sia. The family is subdivided into 3 classes of enzymes, depending on theircatalytic activiy, the mono-STs (ST8Sia1, ST8Sia5 and ST8Sia6), the oligo-ST(ST8Sia3), and the poly-STs (ST8Sia2 and ST8Sia4). The ST8Sia family belongs to the glycosyltransferase family 29 (GT29).


Pssm-ID: 467699  Cd Length: 271  Bit Score: 59.96  E-value: 2.03e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70778904  72 NQCVIITSSSHLLGTKLGPEIERAECTIRMNDAPTSgYSADVGNKTTFrVVAHSSVFR-----VLRKPQEFVNRT---PE 143
Cdd:cd23971  65 KTCAVVGNGGILKNSSCGREIDSADFVIRCNLPPLN-DSKDVGSKTNL-VTANPSILRekfhnLKKRRRPFVERMkvyGN 142

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70778904 144 TVFIFWGPPNKMQ-KPQGSLLRVIQRAGlmfPNMEAYAVSPARMQQFDDLFRGETGKDREkshswLSTGwFTMV-IAVEL 221
Cdd:cd23971 143 ALLLLPAFSYTSNtEPSLRALYTLEDFG---SPQKVLFFNPEYLRNLSRYWKSKGLKARR-----LSTG-LMLVsAALEL 213

                       170       180       190
                ....*....|....*....|....*....|....
gi 70778904 222 CDHVHVYGMVPpdyCSQRPRLQRMPYHYYEPKGP 255
Cdd:cd23971 214 CENVHLYGFWP---FSTDLDGNPISHHYYDNVLP 244
GT29_ST6GALNAC1 cd23973
alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1; ST6GalNAc family members are ...
 69-289 5.43e-10

alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1; ST6GalNAc family members are alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferases that catalyze an alpha-2,6-linkage between sialic acid and the N-acetylgalactosamine residues of glycochains through an 2,6-linkage, by transfering sialic acid from CMP-Sia. ST6GalNAc1 utilize mainly GalNAc-,Galbeta1,3GalNAc-, and Sia2,3Galbeta1,3GalNAc on O-glycans of glycoproteins as acceptors. The ST6GalNac family belongs to glycosyltransferase family 29 (GT29).


Pssm-ID: 467701  Cd Length: 309  Bit Score: 58.99  E-value: 5.43e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70778904  69 SRCNQCVIITSSSHLLGTKLGPEIERAECTIRMNDAPTSGYSADVGNKTTFRVVAHSSVFRVLRKPQEF----VNRTPET 144
Cdd:cd23973  81 DGCIRCAVVGNGGILNGSKMGQEIDSHDYVFRVNGAVIKGYEEDVGTRTSFYVHTAHSITSSLMILQKRgfknIPQDKDI 160

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70778904 145 VFIF---------WGPPNKMQK--PQGSLLRVIQRA--GLMFpNMEAYAVS-PARMQQFDDLFRgeTGKDREKSHSWL-- 208
Cdd:cd23973 161 KYILfpegprdyqWLEALLKNKtiPSGAYYGRRPRSyfSGDF-TEDKYLVLhPDFLRYVKNRFL--RSKTLKGKYWAIyr 237

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70778904 209 -STGWFTMVIAVELCDHVHVYGMVPPDYcsqrprlQRMPYHYYEpKGPDECVTYIqnehsrkgnHHRFITEKRVfssWAQ 287
Cdd:cd23973 238 pTTGAFLLLTALHLCDTVSAYGFITEDY-------RKYPDHYYD-KKKTKLVFYI---------NHDFRLEKKL---WKR 297


                ..
gi 70778904 288 LY 289
Cdd:cd23973 298 LH 299
GT29_ST3GAL2 cd23979
beta-galactoside alpha-2,3-sialyltransferase 2; ST3GAL family transfer sialic acid from ...
 68-229 2.34e-09

beta-galactoside alpha-2,3-sialyltransferase 2; ST3GAL family transfer sialic acid from CMP-Sia to the terminal galactose residues of glycochains through an 2,3-linkage. ST3GAL2 preferentially utilizes the Galbeta1,3GalNAc on glycolipids as an acceptor substrate. Members of this family belong to glycosyltransferase family 29 (GT29).


Pssm-ID: 467707  Cd Length: 279  Bit Score: 57.19  E-value: 2.34e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70778904  68 PSRCNQCVIITSSSHLLGTKLGPEIERAECTIRMNDAPTSGYSADVGNKTTFRVVAHSSVfRVLRKPQEFVNRTPETVFI 147
Cdd:cd23979  77 PSRCRRCAVVGNSGNLRGSGYGKDIDGHDFIMRMNQAPTVGFEADVGSRTTHHFMYPESA-KNLPANVSFVLVPFKTLDL 155

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70778904 148 FW-------GPPNKMQKPQGSLLRVIQRAGLMFpnmeayavSPARMQQFDDLFRGETGKdrekshsWLSTGWFTMVIAVE 220
Cdd:cd23979 156 LWitsalstGQIRFTYAPVKQFLRVDKDKVQIY--------NPAFFKYIHDRWTEHHGR-------YPSTGMLVLFFALH 220


                ....*....
gi 70778904 221 LCDHVHVYG 229
Cdd:cd23979 221 VCDEVNVYG 229
GT29_ST6GALNAC1_2 cd23964
alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 and 2; ST6GalNAc family members ...
 68-291 4.17e-09

alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 and 2; ST6GalNAc family members are alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferases that catalyze an alpha-2,6-linkage between sialic acid and the N-acetylgalactosamine residues of glycochains through an 2,6-linkage, by transfering sialic acid from CMP-Sia. ST6GalNAc1 and 2 utilize mainly GalNAc-,Galbeta1,3GalNAc-, and Sia2,3Galbeta1,3GalNAc on O-glycans of glycoproteins as acceptors. The ST6GalNac family belongs to glycosyltransferase family 29 (GT29).


Pssm-ID: 467692  Cd Length: 292  Bit Score: 56.50  E-value: 4.17e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70778904  68 PSRCNQCVIITSSSHLLGTKLGPEIERAECTIRMNDAPTSGYSADVGNKTTFRVVAHSSVFRVLRKPqefVNRTPETVFI 147
Cdd:cd23964  79 RPRCIRCAVVGNGGILNGSGKGKEIDAHDYVFRVNHALTKGFEKDVGTKTSFYTFFPESLHNSLLKH---VPQDKDTKYL 155

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70778904 148 F----------------WGPPNKMQKpqgsllrviqrAGLMFPNMEAYAVSPARMQQFD-DLFRgetgkdreksH---SW 207
Cdd:cd23964 156 FipfkirdydyldavlsGKPVPDGCD-----------KGKRPPPLFGPKLNATNVRLLHpDFIR----------YlfnRW 214

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70778904 208 L--------STGWFTMVIAVELCDHVHVYGM-VPPDYcsqrprlqrmPYHYYEPKgpdecvtyIQNEHSRKGNHHrFITE 278
Cdd:cd23964 215 LnsstsyrpTTGALMLLTALHTCDQVSVYGFgYDPRF----------SLHYYDKT--------FVKFTVFYANHD-FTNE 275

                       250
                ....*....|....*
gi 70778904 279 KRVfssWAQL--YGI 291
Cdd:cd23964 276 RKL---WRKLheEGI 287
GT29_ST3GAL3 cd23981
beta-galactoside alpha-2,3-sialyltransferase 3; ST3GAL family transfers sialic acid from ...
 70-150 9.41e-09

beta-galactoside alpha-2,3-sialyltransferase 3; ST3GAL family transfers sialic acid from CMP-Sia to the terminal galactose residues of glycochains through an 2,3-linkage. ST3GAL3 can utilize both Galbeta1,3GlcNAc and Galbeta1,4GlcNAc, mainly on glycoproteins and oligosaccharidesas acceptor substrates, but prefers the Galbeta1,3GlcNAc. Members of this family belong to glycosyltransferase family 29 (GT29).


Pssm-ID: 467709  Cd Length: 207  Bit Score: 54.54  E-value: 9.41e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70778904  70 RCNQCVIITSSSHLLGTKLGPEIERAECTIRMNDAPTSGYSADVGNKTTFRVVAHSSvfrVLRKPQEFvnrTPETVFIFW 149
Cdd:cd23981   1 SCRRCIIVGNGGVLANKSLGSKIDDYDVVVRLNSAPVKGFEKDVGSKTTLRITYPEG---AIQKPEQY---EKDSLFVLA 74


                .
gi 70778904 150 G 150
Cdd:cd23981  75 G 75
GT29_ST8SIA4 cd23988
alpha-N-acetylneuraminide alpha-2,8-sialyltransferase 4; ST8Sia4 is a polysialyltransferase ...
 70-251 1.32e-08

alpha-N-acetylneuraminide alpha-2,8-sialyltransferase 4; ST8Sia4 is a polysialyltransferase that can synthesize polysialic acid on neural cell adhesion molecules (NCAMs). ST8Sia4 catalyzes longer polysialicacid formation of NCAMs than ST8Sia2. ST8Sia family members are alpha-N-acetylneuraminide alpha-2,8-sialyltransferases that catalyze an alpha-2,8-linkage between sialic acid and the terminal sialic acid residues of glycochains, by transfering sialic acid from CMP-Sia and they belong to the glycosyltransferase family 29 (GT29).


Pssm-ID: 467716  Cd Length: 278  Bit Score: 54.96  E-value: 1.32e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70778904  70 RCNQCVIITSSSHLLGTKLGPEIERAECTIRMNDAPTSGYSADVGNKTTFRVVAHSSVFRVLrkpQEFVNRTPETVFIfw 149
Cdd:cd23988  63 RFKTCAVVGNSGILLDSGCGKEIDSHDFVIRCNLAPVVEFAADVGTKSDFITMNPSVVQRAF---GGFRNESDREKFV-- 137

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70778904 150 gppnkmqkpqgSLLRVIQRAGLMFPnmeAYAVSPA--RMQQFDDLFRGETGKDREKSHS----------WL--------- 208
Cdd:cd23988 138 -----------HRLSMLNDSVLWIP---AFMVKGGekHVEWVNALILKNKLKVRTAYPSlrlihavrgyWLtnkvnikrp 203

                       170       180       190       200
                ....*....|....*....|....*....|....*....|....
gi 70778904 209 STGWFTMVIAVELCDHVHVYGMVP-PDYCSQRPrlqrMPYHYYE 251
Cdd:cd23988 204 STGLLMYTLATRFCDEIHLYGFWPfPKDANGNP----VKYHYYD 243
GT29_ST8SIA6 cd23991
alpha-N-acetylneuraminide alpha-2,8-sialyltransferase 6; alpha-N-acetylneuraminide alpha-2, ...
 72-268 4.94e-08

alpha-N-acetylneuraminide alpha-2,8-sialyltransferase 6; alpha-N-acetylneuraminide alpha-2,8-sialyltransferase 6 (also known as alpha-2,8-sialyltransferase 8F) prefers O-glycans to N-glycans or glycolipids as acceptor substrates. ST8Sia family members are alpha-N-acetylneuraminide alpha-2,8-sialyltransferases that catalyze an alpha-2,8-linkage between sialic acid and the terminal sialic acid residues of glycochains, by transfering sialic acid from CMP-Sia. The ST8Sia family belongs to glycosyltransferase family 29(GT29).


Pssm-ID: 467719  Cd Length: 273  Bit Score: 53.22  E-value: 4.94e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70778904  72 NQCVIITSSSHLLGTKLGPEIERAECTIRMNDAPTSG-YSADVGNKTTFrVVAHSSVFrvLRKPQEFvnrtpetvfifwg 150
Cdd:cd23991  65 KQCAVVGNGGILKNSSCGAEIDQADFVFRCNLPPTGGnISKDVGSKTNL-VTANPSII--SIKYAKL------------- 128

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70778904 151 ppNKMQKPQGSLLRVIQRAGLMFPnmeAYAVSPARMQQFDDLFRGETGKDREK------------SHSW---------LS 209
Cdd:cd23991 129 --NERRKPFLETVSVYGDAFLLLP---AFSYRSNTALSFKVYYTLEDFKAKQKviffhpiylkhlAQFWrskgvqvyrLS 203

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|....*....
gi 70778904 210 TGWFTMVIAVELCDHVHVYGMVPpdyCSQRPRLQRMPYHYYEPKGPDECVTYIQNEHSR 268
Cdd:cd23991 204 TGLMITSAALELCEEVKLYGFWP---FSKNTEGKPISHHYYDNQLPKPGFHSMPKEFYQ 259
GT29_ST8SIA1 cd23989
alpha-N-acetylneuraminide alpha-2,8-sialyltransferase 1; Alpha-N-acetylneuraminide alpha-2, ...
 67-256 3.07e-06

alpha-N-acetylneuraminide alpha-2,8-sialyltransferase 1; Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase 1 (also known as ganglioside GD3 synthase) adds sialic acids to GM3 ganglioside. ST8Sia family members are alpha-N-acetylneuraminide alpha-2,8-sialyltransferases that catalyze analpha-2,8-linkage between sialic acid and the terminal sialic acid residues of glycochains, by transfering sialic acid from CMP-Sia. The ST8Sia family belongs to the glycosyltransferase family 29 (GT29).


Pssm-ID: 467717  Cd Length: 272  Bit Score: 47.52  E-value: 3.07e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70778904  67 LPSRCNQCVIITSSSHLLGTKLGPEIERAECTIRMNDAP-TSGYSADVGNKTTFrVVAHSSVFR-----VLRKPQEFVnr 140
Cdd:cd23989  59 LQLPLKKCSVVGNGGILKNSGCGQQIDRADFVMRCNLPPlSREYTDDVGTKTQL-VTANPSIIDkrfqnLLWSRKSFV-- 135

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70778904 141 tpETVFIF-----WGPPNKMQKPQGSLLRVIQRAGLMFPNMEAYAVSParmqqfdDLFR--GETGKDREKSHSWLSTGWF 213
Cdd:cd23989 136 --ESMKVYgrsyiYMPAFSMKTGTDPSLRVYYTLADVGANQTVLFANP-------NFLRnvGKFWKSKGVHAKRLSTGLF 206

                       170       180       190       200
                ....*....|....*....|....*....|....*....|...
gi 70778904 214 TMVIAVELCDHVHVYGMVPpdyCSQRPRLQRMPYHYYEPKGPD 256
Cdd:cd23989 207 LVSAALGLCEEVTIYGFWP---FSVDLDERTISHHYYDNVLPD 246
GT29_ST6GALNAC2 cd23972
alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2; ST6GalNAc family members are ...
 67-253 3.97e-06

alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2; ST6GalNAc family members are alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferases that catalyze an alpha-2,6-linkage between sialic acid and the N-acetylgalactosamine residues of glycochains through an 2,6-linkage, by transfering sialic acid from CMP-Sia. ST6GalNAc2 utilize mainly GalNAc-,Galbeta1,3GalNAc-, and Sia2,3Galbeta1,3GalNAc on O-glycans of glycoproteins as acceptors. The ST6GalNac family belongs to glycosyltransferase family 29 (GT29).


Pssm-ID: 467700  Cd Length: 308  Bit Score: 47.51  E-value: 3.97e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70778904  67 LPSRCNQCVIITSSSHLLGTKLGPEIERAECTIRMNDAPTSGYSADVGNKTTFRVVAHSSVFRVLRKPQEF-VNRTPET- 144
Cdd:cd23972  78 TPGKCIRCAVVGNGGILNGSRQGRAIDAHDYVFRLNGAVIKGFEEDVGTKTSFYGFTVNTMKNSLISYWNLgFTRTPQGq 157

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70778904 145 ----VFI-------------FWGPP-----NKMQKPQG--SLLRVIQRAGLMFPNMEAYavsparmqqFDDLFRGETGKD 200
Cdd:cd23972 158 dlqyIFIpsdirdyvmlrsaILGVPvpeglDKGDRPHKyfGPEASAKKFKLLHPDFISY---------LTDRFLKSKLLN 228

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|....
gi 70778904 201 REKSHSWL-STGWFTMVIAVELCDHVHVYGMVPPDYcsqrprlQRMPYHYYEPK 253
Cdd:cd23972 229 THYGHLYMpSTGALMLLTALHTCDQVSAYGFITSNY-------WKFSDHYYERK 275
GT29_ST6GALNAC2L cd23974
alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2-like; ST6GalNAc family members are ...
 69-253 7.47e-06

alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2-like; ST6GalNAc family members are alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferases that catalyze an alpha-2,6-linkage between sialic acid and the N-acetylgalactosamine residues of glycochains through an 2,6-linkage, by transfering sialic acid from CMP-Sia. The ST6GalNac family belongs to glycosyltransferase family 29 (GT29).


Pssm-ID: 467702  Cd Length: 309  Bit Score: 46.67  E-value: 7.47e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70778904  69 SRCNQCVIITSSSHLLGTKLGPEIERAECTIRMNDAPTSGYSADVGNKTTFRVVAHSSVFRVLRK---------PQefvn 139
Cdd:cd23974  82 SPCIRCAVVGNGGILNGSRMGAEIDGHDYVFRVNGAITKGFEKDVGRRTSFYTFSTNTLMNSLRAyagvgfngpPQ---- 157

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70778904 140 rTPETVFIFWGPPNK--MQKPQGSLLRVIQRAGLMFPNMEAYAVSPARMQQF------------DDLFRGETGKDREKSH 205
Cdd:cd23974 158 -SKETRYIFLPDHDRdyLLVKAALTHTPIDRGRDKSKRPSKYFGKDVTAEKFkiyhpdfirylrNRFLWSPILNTKQRDI 236

                       170       180       190       200
                ....*....|....*....|....*....|....*....|....*...
gi 70778904 206 SWLSTGWFTMVIAVELCDHVHVYGMVPPDYcsqrprlQRMPYHYYEPK 253
Cdd:cd23974 237 YRPSTGAVMLLAALHTCDQVSAYGFMTPDY-------GKYSDHYYDKT 277
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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