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Conserved domains on  [gi|68989245|ref|NP_001020415|]
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keratin associated protein 31-2 [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Keratin_B2_2 pfam13885
Keratin, high sulfur B2 protein;
64-107 1.29e-08

Keratin, high sulfur B2 protein;


:

Pssm-ID: 464017 [Multi-domain]  Cd Length: 45  Bit Score: 48.53  E-value: 1.29e-08
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 68989245    64 CCPPTCCDPASCDSNCCKPT-CVTICCSTPCCQPSCCVPTCCQPS 107
Cdd:pfam13885   1 CCQPSCCQPSCCQPSCCQPScCQPSCCQPSCCRPSCCRSSCCQPT 45
Keratin_B2 super family cl37504
Keratin, high sulfur B2 protein; High sulfur proteins are cysteine-rich proteins synthesized ...
 5-125 6.82e-08

Keratin, high sulfur B2 protein; High sulfur proteins are cysteine-rich proteins synthesized during the differentiation of hair matrix cells, and form hair fibres in association with hair keratin intermediate filaments. This family has been divided up into four regions, with the second region containing 8 copies of a short repeat. This family is also known as B2 or KAP1.


The actual alignment was detected with superfamily member pfam01500:

Pssm-ID: 366678 [Multi-domain]  Cd Length: 161  Bit Score: 49.40  E-value: 6.82e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 68989245     5 CQPCCCKTTSCRTSSSSESSSESSCPVFICCAPSW--CSTPCCCKSICCHSTKTVNSCSQLCCPPTCCDPA-SCDSNCCK 81
Cdd:pfam01500  25 CQPCCCQSSCCRPSCCQTSCCQPTTFQSSCCRPTCqpCCQTSCCQPTCCQTSSCQTGCGGIGYGQEGSSGAvSSRTRWCR 104

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 68989245    82 PTC-VTICCSTPCCQPSCCVPTCCQPSLFQL-CCQPTCCETSCCKT 125
Cdd:pfam01500 105 PDCrVEGTCLPPCCVVSCTPPTCCQLHHAQAsCCRPSYCGQSCCRP 150
 
Name Accession Description Interval E-value
Keratin_B2_2 pfam13885
Keratin, high sulfur B2 protein;
64-107 1.29e-08

Keratin, high sulfur B2 protein;


Pssm-ID: 464017 [Multi-domain]  Cd Length: 45  Bit Score: 48.53  E-value: 1.29e-08
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 68989245    64 CCPPTCCDPASCDSNCCKPT-CVTICCSTPCCQPSCCVPTCCQPS 107
Cdd:pfam13885   1 CCQPSCCQPSCCQPSCCQPScCQPSCCQPSCCRPSCCRSSCCQPT 45
Keratin_B2 pfam01500
Keratin, high sulfur B2 protein; High sulfur proteins are cysteine-rich proteins synthesized ...
 5-125 6.82e-08

Keratin, high sulfur B2 protein; High sulfur proteins are cysteine-rich proteins synthesized during the differentiation of hair matrix cells, and form hair fibres in association with hair keratin intermediate filaments. This family has been divided up into four regions, with the second region containing 8 copies of a short repeat. This family is also known as B2 or KAP1.


Pssm-ID: 366678 [Multi-domain]  Cd Length: 161  Bit Score: 49.40  E-value: 6.82e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 68989245     5 CQPCCCKTTSCRTSSSSESSSESSCPVFICCAPSW--CSTPCCCKSICCHSTKTVNSCSQLCCPPTCCDPA-SCDSNCCK 81
Cdd:pfam01500  25 CQPCCCQSSCCRPSCCQTSCCQPTTFQSSCCRPTCqpCCQTSCCQPTCCQTSSCQTGCGGIGYGQEGSSGAvSSRTRWCR 104

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 68989245    82 PTC-VTICCSTPCCQPSCCVPTCCQPSLFQL-CCQPTCCETSCCKT 125
Cdd:pfam01500 105 PDCrVEGTCLPPCCVVSCTPPTCCQLHHAQAsCCRPSYCGQSCCRP 150
NosR COG3901
Transcriptional regulator NosR of nitric oxide reductase [Transcription];
29-118 5.19e-04

Transcriptional regulator NosR of nitric oxide reductase [Transcription];


Pssm-ID: 443108 [Multi-domain]  Cd Length: 713  Bit Score: 39.53  E-value: 5.19e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 68989245  29 CPVFICCAPSWCSTPCCCKSICChstktvnsCSQLCCPPTCCDPASCDSNCCKPTCVTICCstpCCQPSCCVPTCCQpsl 108
Cdd:COG3901 608 RLCLLGLALAAAALARRRLWRRR--------RRECCCGCCCCCCKCCCIVIIIDGIIIINE---CCCCCCLCCRRCQ--- 673

                        90
                ....*....|
gi 68989245 109 fQLCCQPTCC 118
Cdd:COG3901 674 -DDPLCPPRI 682
 
Name Accession Description Interval E-value
Keratin_B2_2 pfam13885
Keratin, high sulfur B2 protein;
64-107 1.29e-08

Keratin, high sulfur B2 protein;


Pssm-ID: 464017 [Multi-domain]  Cd Length: 45  Bit Score: 48.53  E-value: 1.29e-08
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 68989245    64 CCPPTCCDPASCDSNCCKPT-CVTICCSTPCCQPSCCVPTCCQPS 107
Cdd:pfam13885   1 CCQPSCCQPSCCQPSCCQPScCQPSCCQPSCCRPSCCRSSCCQPT 45
Keratin_B2 pfam01500
Keratin, high sulfur B2 protein; High sulfur proteins are cysteine-rich proteins synthesized ...
 5-125 6.82e-08

Keratin, high sulfur B2 protein; High sulfur proteins are cysteine-rich proteins synthesized during the differentiation of hair matrix cells, and form hair fibres in association with hair keratin intermediate filaments. This family has been divided up into four regions, with the second region containing 8 copies of a short repeat. This family is also known as B2 or KAP1.


Pssm-ID: 366678 [Multi-domain]  Cd Length: 161  Bit Score: 49.40  E-value: 6.82e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 68989245     5 CQPCCCKTTSCRTSSSSESSSESSCPVFICCAPSW--CSTPCCCKSICCHSTKTVNSCSQLCCPPTCCDPA-SCDSNCCK 81
Cdd:pfam01500  25 CQPCCCQSSCCRPSCCQTSCCQPTTFQSSCCRPTCqpCCQTSCCQPTCCQTSSCQTGCGGIGYGQEGSSGAvSSRTRWCR 104

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 68989245    82 PTC-VTICCSTPCCQPSCCVPTCCQPSLFQL-CCQPTCCETSCCKT 125
Cdd:pfam01500 105 PDCrVEGTCLPPCCVVSCTPPTCCQLHHAQAsCCRPSYCGQSCCRP 150
Keratin_B2 pfam01500
Keratin, high sulfur B2 protein; High sulfur proteins are cysteine-rich proteins synthesized ...
 2-122 1.91e-07

Keratin, high sulfur B2 protein; High sulfur proteins are cysteine-rich proteins synthesized during the differentiation of hair matrix cells, and form hair fibres in association with hair keratin intermediate filaments. This family has been divided up into four regions, with the second region containing 8 copies of a short repeat. This family is also known as B2 or KAP1.


Pssm-ID: 366678 [Multi-domain]  Cd Length: 161  Bit Score: 48.25  E-value: 1.91e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 68989245     2 THTCQPCCCKTTSCRTSSSSESSSESSCPVfiCCAPSWCSTPCCCKSICCHSTKTVNSCSQLCCPPTCCDPASCDSNCCK 81
Cdd:pfam01500  42 TSCCQPTTFQSSCCRPTCQPCCQTSCCQPT--CCQTSSCQTGCGGIGYGQEGSSGAVSSRTRWCRPDCRVEGTCLPPCCV 119

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 68989245    82 PTCV-TICCSTPCCQPSCCVPTCCQPSLFQLCCQPTCCETSC 122
Cdd:pfam01500 120 VSCTpPTCCQLHHAQASCCRPSYCGQSCCRPACCCQCSEPTC 161
Keratin_B2_2 pfam13885
Keratin, high sulfur B2 protein;
84-131 2.87e-07

Keratin, high sulfur B2 protein;


Pssm-ID: 464017 [Multi-domain]  Cd Length: 45  Bit Score: 45.07  E-value: 2.87e-07
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 68989245    84 CVTICCSTPCCQPSCCVPTCCQPSlfqlCCQPTCCETSCCKTISFKPS 131
Cdd:pfam13885   2 CQPSCCQPSCCQPSCCQPSCCQPS----CCQPSCCRPSCCRSSCCQPT 45
Keratin_B2 pfam01500
Keratin, high sulfur B2 protein; High sulfur proteins are cysteine-rich proteins synthesized ...
 9-132 5.01e-07

Keratin, high sulfur B2 protein; High sulfur proteins are cysteine-rich proteins synthesized during the differentiation of hair matrix cells, and form hair fibres in association with hair keratin intermediate filaments. This family has been divided up into four regions, with the second region containing 8 copies of a short repeat. This family is also known as B2 or KAP1.


Pssm-ID: 366678 [Multi-domain]  Cd Length: 161  Bit Score: 47.09  E-value: 5.01e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 68989245     9 CCKTTSCRTSSSSESSSESSCPVFICCAPSWCSTPCCCKSICCHSTKTVNSCSQ---------LCCPPTCCDPASCDSNC 79
Cdd:pfam01500   3 CCGTSFCGFPTCSTGGTCGSGCCQPCCCQSSCCRPSCCQTSCCQPTTFQSSCCRptcqpccqtSCCQPTCCQTSSCQTGC 82

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 68989245    80 CKPT----------------CVTICCSTPCCQPSCCVPTCCQPSlfqlCCQPTCCETSCCKTISFKPSC 132
Cdd:pfam01500  83 GGIGygqegssgavssrtrwCRPDCRVEGTCLPPCCVVSCTPPT----CCQLHHAQASCCRPSYCGQSC 147
Keratin_B2_2 pfam13885
Keratin, high sulfur B2 protein;
88-131 2.35e-06

Keratin, high sulfur B2 protein;


Pssm-ID: 464017 [Multi-domain]  Cd Length: 45  Bit Score: 42.75  E-value: 2.35e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 68989245    88 CCSTPCCQPSCCVPTCCQPSlfqlCCQPTCCETSCCKTISFKPS 131
Cdd:pfam13885   1 CCQPSCCQPSCCQPSCCQPS----CCQPSCCQPSCCRPSCCRSS 40
NosR COG3901
Transcriptional regulator NosR of nitric oxide reductase [Transcription];
29-118 5.19e-04

Transcriptional regulator NosR of nitric oxide reductase [Transcription];


Pssm-ID: 443108 [Multi-domain]  Cd Length: 713  Bit Score: 39.53  E-value: 5.19e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 68989245  29 CPVFICCAPSWCSTPCCCKSICChstktvnsCSQLCCPPTCCDPASCDSNCCKPTCVTICCstpCCQPSCCVPTCCQpsl 108
Cdd:COG3901 608 RLCLLGLALAAAALARRRLWRRR--------RRECCCGCCCCCCKCCCIVIIIDGIIIINE---CCCCCCLCCRRCQ--- 673

                        90
                ....*....|
gi 68989245 109 fQLCCQPTCC 118
Cdd:COG3901 674 -DDPLCPPRI 682
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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