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Conserved domains on  [gi|68448537|ref|NP_001020329|]
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HLA class II histocompatibility antigen gamma chain isoform c [Homo sapiens]

Protein Classification

MHC2-interact domain-containing protein( domain architecture ID 10558255)

MHC2-interact domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
MHC2-interact pfam09307
CLIP, MHC2 interacting; Members of this family are found in class II invariant ...
 17-129 2.34e-50

CLIP, MHC2 interacting; Members of this family are found in class II invariant chain-associated peptide (CLIP), and are required for association with class II major histocompatibility complex (MHC) in the MHC class II processing pathway.


:

Pssm-ID: 462750  Cd Length: 109  Bit Score: 156.88  E-value: 2.34e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 68448537    17 MDDQRDLISNNEQLPMLGRRPGAPESkCSRGALYTGFSILVTLLLAGQATTAYFLYQQQGRLDKLTVTSQNLQLENLRMK 96
Cdd:pfam09307   1 EEQQRDLISNPSSEPVLNVRGGARSS-LSRGAKITGLSILVALLIAGQAVTAYFVYQQKGQITKLTQTSQNLQLELLRMK 79

                          90       100       110
                  ....*....|....*....|....*....|...
gi 68448537    97 LPKPPKPvskMRMATPLLMQALPMGALPQGPMQ 129
Cdd:pfam09307  80 LPKPSKP---MRMAMPMNNMPLVMDYSDPAPSQ 109
 
Name Accession Description Interval E-value
MHC2-interact pfam09307
CLIP, MHC2 interacting; Members of this family are found in class II invariant ...
 17-129 2.34e-50

CLIP, MHC2 interacting; Members of this family are found in class II invariant chain-associated peptide (CLIP), and are required for association with class II major histocompatibility complex (MHC) in the MHC class II processing pathway.


Pssm-ID: 462750  Cd Length: 109  Bit Score: 156.88  E-value: 2.34e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 68448537    17 MDDQRDLISNNEQLPMLGRRPGAPESkCSRGALYTGFSILVTLLLAGQATTAYFLYQQQGRLDKLTVTSQNLQLENLRMK 96
Cdd:pfam09307   1 EEQQRDLISNPSSEPVLNVRGGARSS-LSRGAKITGLSILVALLIAGQAVTAYFVYQQKGQITKLTQTSQNLQLELLRMK 79

                          90       100       110
                  ....*....|....*....|....*....|...
gi 68448537    97 LPKPPKPvskMRMATPLLMQALPMGALPQGPMQ 129
Cdd:pfam09307  80 LPKPSKP---MRMAMPMNNMPLVMDYSDPAPSQ 109
 
Name Accession Description Interval E-value
MHC2-interact pfam09307
CLIP, MHC2 interacting; Members of this family are found in class II invariant ...
 17-129 2.34e-50

CLIP, MHC2 interacting; Members of this family are found in class II invariant chain-associated peptide (CLIP), and are required for association with class II major histocompatibility complex (MHC) in the MHC class II processing pathway.


Pssm-ID: 462750  Cd Length: 109  Bit Score: 156.88  E-value: 2.34e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 68448537    17 MDDQRDLISNNEQLPMLGRRPGAPESkCSRGALYTGFSILVTLLLAGQATTAYFLYQQQGRLDKLTVTSQNLQLENLRMK 96
Cdd:pfam09307   1 EEQQRDLISNPSSEPVLNVRGGARSS-LSRGAKITGLSILVALLIAGQAVTAYFVYQQKGQITKLTQTSQNLQLELLRMK 79

                          90       100       110
                  ....*....|....*....|....*....|...
gi 68448537    97 LPKPPKPvskMRMATPLLMQALPMGALPQGPMQ 129
Cdd:pfam09307  80 LPKPSKP---MRMAMPMNNMPLVMDYSDPAPSQ 109
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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