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Conserved domains on  [gi|62955721|ref|NP_001017872|]
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inositol 1,4,5-trisphosphate receptor-interacting protein precursor [Danio rerio]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Mab-21_C super family cl48430
Mab-21 protein HhH/H2TH-like domain; This family contains Mab-21 and Mab-21 like proteins. In ...
 390-462 2.08e-07

Mab-21 protein HhH/H2TH-like domain; This family contains Mab-21 and Mab-21 like proteins. In C. elegans these proteins are required for several aspects of embryonic development.


The actual alignment was detected with superfamily member pfam20266:

Pssm-ID: 466416  Cd Length: 102  Bit Score: 49.16  E-value: 2.08e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 62955721   390 CHIHCLQIVAFLHKKQT--TLTGRSAFCNYHIKTALLHLLLSKRPAM-WQPQNLDSRLRDLLSFLQQSLEEKKLYH 462
Cdd:pfam20266   1 CRKKCLRILKKLKEPGKrdVKTELSKICSYHLKTLFLWECEKHPDDSdWDKENLSDRFLGLLEELHKCLRNGKLPH 76
DUF5595 super family cl39478
Domain of unknown function (DUF5595); This domain is found in Nude C 80 (Ndc80) proteins which ...
 23-63 7.35e-03

Domain of unknown function (DUF5595); This domain is found in Nude C 80 (Ndc80) proteins which can be found in species such as Homo sapiens. Ndc80 protein complexes are a core component of the end-on attachment sites for kinetochore microtubules. Ndc80 is also known as Hec1, for highly expressed in cancer 1.


The actual alignment was detected with superfamily member pfam18077:

Pssm-ID: 465636 [Multi-domain]  Cd Length: 73  Bit Score: 35.37  E-value: 7.35e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 62955721    23 FPNENTTVPEQDEDLLARMKE-------HQEKLEAEQKRLEQEISQNE 63
Cdd:pfam18077  24 FMQGEDTFEEEDAELLSKLKElynvdeaLIESLEEEHKRLNEEIERLE 71
 
Name Accession Description Interval E-value
Mab-21_C pfam20266
Mab-21 protein HhH/H2TH-like domain; This family contains Mab-21 and Mab-21 like proteins. In ...
 390-462 2.08e-07

Mab-21 protein HhH/H2TH-like domain; This family contains Mab-21 and Mab-21 like proteins. In C. elegans these proteins are required for several aspects of embryonic development.


Pssm-ID: 466416  Cd Length: 102  Bit Score: 49.16  E-value: 2.08e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 62955721   390 CHIHCLQIVAFLHKKQT--TLTGRSAFCNYHIKTALLHLLLSKRPAM-WQPQNLDSRLRDLLSFLQQSLEEKKLYH 462
Cdd:pfam20266   1 CRKKCLRILKKLKEPGKrdVKTELSKICSYHLKTLFLWECEKHPDDSdWDKENLSDRFLGLLEELHKCLRNGKLPH 76
DUF5595 pfam18077
Domain of unknown function (DUF5595); This domain is found in Nude C 80 (Ndc80) proteins which ...
 23-63 7.35e-03

Domain of unknown function (DUF5595); This domain is found in Nude C 80 (Ndc80) proteins which can be found in species such as Homo sapiens. Ndc80 protein complexes are a core component of the end-on attachment sites for kinetochore microtubules. Ndc80 is also known as Hec1, for highly expressed in cancer 1.


Pssm-ID: 465636 [Multi-domain]  Cd Length: 73  Bit Score: 35.37  E-value: 7.35e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 62955721    23 FPNENTTVPEQDEDLLARMKE-------HQEKLEAEQKRLEQEISQNE 63
Cdd:pfam18077  24 FMQGEDTFEEEDAELLSKLKElynvdeaLIESLEEEHKRLNEEIERLE 71
 
Name Accession Description Interval E-value
Mab-21_C pfam20266
Mab-21 protein HhH/H2TH-like domain; This family contains Mab-21 and Mab-21 like proteins. In ...
 390-462 2.08e-07

Mab-21 protein HhH/H2TH-like domain; This family contains Mab-21 and Mab-21 like proteins. In C. elegans these proteins are required for several aspects of embryonic development.


Pssm-ID: 466416  Cd Length: 102  Bit Score: 49.16  E-value: 2.08e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 62955721   390 CHIHCLQIVAFLHKKQT--TLTGRSAFCNYHIKTALLHLLLSKRPAM-WQPQNLDSRLRDLLSFLQQSLEEKKLYH 462
Cdd:pfam20266   1 CRKKCLRILKKLKEPGKrdVKTELSKICSYHLKTLFLWECEKHPDDSdWDKENLSDRFLGLLEELHKCLRNGKLPH 76
DUF5595 pfam18077
Domain of unknown function (DUF5595); This domain is found in Nude C 80 (Ndc80) proteins which ...
 23-63 7.35e-03

Domain of unknown function (DUF5595); This domain is found in Nude C 80 (Ndc80) proteins which can be found in species such as Homo sapiens. Ndc80 protein complexes are a core component of the end-on attachment sites for kinetochore microtubules. Ndc80 is also known as Hec1, for highly expressed in cancer 1.


Pssm-ID: 465636 [Multi-domain]  Cd Length: 73  Bit Score: 35.37  E-value: 7.35e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 62955721    23 FPNENTTVPEQDEDLLARMKE-------HQEKLEAEQKRLEQEISQNE 63
Cdd:pfam18077  24 FMQGEDTFEEEDAELLSKLKElynvdeaLIESLEEEHKRLNEEIERLE 71
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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