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Conserved domains on  [gi|61557041|ref|NP_001013149|]
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tetratricopeptide repeat protein 5 [Rattus norvegicus]

Protein Classification

tetratricopeptide repeat protein 5( domain architecture ID 11421408)

tetratricopeptide repeat protein 5 (TTC5) is a cofactor involved in the regulation of various cellular mechanisms such as actin regulation, autophagy, chromatin regulation, and DNA repair

CATH:  1.25.40.10
Gene Ontology:  GO:0043022|GO:0006281|GO:0006974|GO:0003677
PubMed:  10517866|30708253
SCOP:  3001345

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TTC5_OB pfam16669
Tetratricopeptide repeat protein 5 OB fold domain; This OB fold domain is located at the ...
 318-432 1.88e-59

Tetratricopeptide repeat protein 5 OB fold domain; This OB fold domain is located at the C-terminus of Tetratricopeptide repeat protein 5 and is required for effective p53 response.


:

Pssm-ID: 465225  Cd Length: 115  Bit Score: 189.74  E-value: 1.88e-59
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61557041   318 TLQLKPLSTLQPGVNSGTVVLGKVVFSLTTEEKVPFTFGLVDSDGPCYAVMVYNVVQSWGVLIGDSVAIPEPNLRHHQIQ 397
Cdd:pfam16669   1 KLKRATLDDLKEGLNKGKVVLGKVVGSITHEEPVPLTFVLVDSEGTCFVVTVYNLAQGKGVKIGDSVAIPEPYLRFIDFS 80

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 61557041   398 HKGKDYSFSSVRVETPLLLVVNGKPQNSSSQASAT 432
Cdd:pfam16669  81 WKGKHFQFKSIRVDTPLQLLVNGKKLGPDSQARAV 115
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
67-274 1.90e-14

Tetratricopeptide (TPR) repeat [General function prediction only];


:

Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 72.73  E-value: 1.90e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61557041  67 EAQALMLKGKALNVTPDYSpEAEVLLSKAVKLEPELVEAWNQLGEVYWKKGDVAAAHTCFSGALTHC-KNKVSLQNLSMV 145
Cdd:COG0457   7 DAEAYNNLGLAYRRLGRYE-EAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDpDDAEALNNLGLA 85

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61557041 146 LRQL-QTDSGDEHSRHvmdsvrqaklAVQMDVLDGRSWYILGNAYLSLyfntGQNpkisQQALSAYAQAEKVDrkaSSNP 224
Cdd:COG0457  86 LQALgRYEEALEDYDK----------ALELDPDDAEALYNLGLALLEL----GRY----DEAIEAYERALELD---PDDA 144

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|
gi 61557041 225 DLHLNRATLHKYEESYGEALEGFSQAATLDPAWPEPQQREQQLLEFLSRL 274
Cdd:COG0457 145 DALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAE 194
 
Name Accession Description Interval E-value
TTC5_OB pfam16669
Tetratricopeptide repeat protein 5 OB fold domain; This OB fold domain is located at the ...
 318-432 1.88e-59

Tetratricopeptide repeat protein 5 OB fold domain; This OB fold domain is located at the C-terminus of Tetratricopeptide repeat protein 5 and is required for effective p53 response.


Pssm-ID: 465225  Cd Length: 115  Bit Score: 189.74  E-value: 1.88e-59
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61557041   318 TLQLKPLSTLQPGVNSGTVVLGKVVFSLTTEEKVPFTFGLVDSDGPCYAVMVYNVVQSWGVLIGDSVAIPEPNLRHHQIQ 397
Cdd:pfam16669   1 KLKRATLDDLKEGLNKGKVVLGKVVGSITHEEPVPLTFVLVDSEGTCFVVTVYNLAQGKGVKIGDSVAIPEPYLRFIDFS 80

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 61557041   398 HKGKDYSFSSVRVETPLLLVVNGKPQNSSSQASAT 432
Cdd:pfam16669  81 WKGKHFQFKSIRVDTPLQLLVNGKKLGPDSQARAV 115
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
67-274 1.90e-14

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 72.73  E-value: 1.90e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61557041  67 EAQALMLKGKALNVTPDYSpEAEVLLSKAVKLEPELVEAWNQLGEVYWKKGDVAAAHTCFSGALTHC-KNKVSLQNLSMV 145
Cdd:COG0457   7 DAEAYNNLGLAYRRLGRYE-EAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDpDDAEALNNLGLA 85

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61557041 146 LRQL-QTDSGDEHSRHvmdsvrqaklAVQMDVLDGRSWYILGNAYLSLyfntGQNpkisQQALSAYAQAEKVDrkaSSNP 224
Cdd:COG0457  86 LQALgRYEEALEDYDK----------ALELDPDDAEALYNLGLALLEL----GRY----DEAIEAYERALELD---PDDA 144

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|
gi 61557041 225 DLHLNRATLHKYEESYGEALEGFSQAATLDPAWPEPQQREQQLLEFLSRL 274
Cdd:COG0457 145 DALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAE 194
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 69-135 1.60e-03

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 40.30  E-value: 1.60e-03
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 61557041  69 QALMLKGKALNVTPDYSpEAEVLLSKAVKLEPELVEAWNQLGEVYWKKGDVAAAHTCFSGALTHCKN 135
Cdd:cd24142   1 DELLEKAEELLDQGNFE-LALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDPD 66
TPR_11 pfam13414
TPR repeat;
86-117 2.66e-03

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 35.53  E-value: 2.66e-03
                          10        20        30
                  ....*....|....*....|....*....|..
gi 61557041    86 PEAEVLLSKAVKLEPELVEAWNQLGEVYWKKG 117
Cdd:pfam13414  11 EEAIEAYKKALKLDPDNPEAYYNLGLAYYKLG 42
 
Name Accession Description Interval E-value
TTC5_OB pfam16669
Tetratricopeptide repeat protein 5 OB fold domain; This OB fold domain is located at the ...
 318-432 1.88e-59

Tetratricopeptide repeat protein 5 OB fold domain; This OB fold domain is located at the C-terminus of Tetratricopeptide repeat protein 5 and is required for effective p53 response.


Pssm-ID: 465225  Cd Length: 115  Bit Score: 189.74  E-value: 1.88e-59
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61557041   318 TLQLKPLSTLQPGVNSGTVVLGKVVFSLTTEEKVPFTFGLVDSDGPCYAVMVYNVVQSWGVLIGDSVAIPEPNLRHHQIQ 397
Cdd:pfam16669   1 KLKRATLDDLKEGLNKGKVVLGKVVGSITHEEPVPLTFVLVDSEGTCFVVTVYNLAQGKGVKIGDSVAIPEPYLRFIDFS 80

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 61557041   398 HKGKDYSFSSVRVETPLLLVVNGKPQNSSSQASAT 432
Cdd:pfam16669  81 WKGKHFQFKSIRVDTPLQLLVNGKKLGPDSQARAV 115
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
67-274 1.90e-14

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 72.73  E-value: 1.90e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61557041  67 EAQALMLKGKALNVTPDYSpEAEVLLSKAVKLEPELVEAWNQLGEVYWKKGDVAAAHTCFSGALTHC-KNKVSLQNLSMV 145
Cdd:COG0457   7 DAEAYNNLGLAYRRLGRYE-EAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDpDDAEALNNLGLA 85

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61557041 146 LRQL-QTDSGDEHSRHvmdsvrqaklAVQMDVLDGRSWYILGNAYLSLyfntGQNpkisQQALSAYAQAEKVDrkaSSNP 224
Cdd:COG0457  86 LQALgRYEEALEDYDK----------ALELDPDDAEALYNLGLALLEL----GRY----DEAIEAYERALELD---PDDA 144

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|
gi 61557041 225 DLHLNRATLHKYEESYGEALEGFSQAATLDPAWPEPQQREQQLLEFLSRL 274
Cdd:COG0457 145 DALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAE 194
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
96-273 8.73e-13

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 67.72  E-value: 8.73e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61557041  96 VKLEPELVEAWNQLGEVYWKKGDVAAAHTCFSGALTHCKNK-VSLQNLSMVLRQLQtdsgdehsrHVMDSVRQAKLAVQM 174
Cdd:COG0457   1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDaEALYNLGLAYLRLG---------RYEEALADYEQALEL 71

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61557041 175 DVLDGRSWYILGNAYLSLyfntGQNpkisQQALSAYAQAEKVDrkaSSNPDLHLNRATLHKYEESYGEALEGFSQAATLD 254
Cdd:COG0457  72 DPDDAEALNNLGLALQAL----GRY----EEALEDYDKALELD---PDDAEALYNLGLALLELGRYDEAIEAYERALELD 140

                       170
                ....*....|....*....
gi 61557041 255 PAWPEPQQREQQLLEFLSR 273
Cdd:COG0457 141 PDDADALYNLGIALEKLGR 159
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 87-279 9.78e-09

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 56.28  E-value: 9.78e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61557041  87 EAEVLLSKAVKLEPELVEAWNQLGEVYWKKGDVAAAHTCFSGAL-THCKNKVSLQNLSMVLRQLqtdsGDEHsrhvmDSV 165
Cdd:COG2956  60 RAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLeLDPDDAEALRLLAEIYEQE----GDWE-----KAI 130

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61557041 166 RQAKLAVQMDVLDGRSWYILGNAYLSLyfntgQNPKisqQALSAYAQAEKVDRKassNPDLHLNRATLHKYEESYGEALE 245
Cdd:COG2956 131 EVLERLLKLGPENAHAYCELAELYLEQ-----GDYD---EAIEALEKALKLDPD---CARALLLLAELYLEQGDYEEAIA 199

                       170       180       190
                ....*....|....*....|....*....|....
gi 61557041 246 GFSQAATLDPAWPEPQQREQQLLEFLSRLTNLLA 279
Cdd:COG2956 200 ALERALEQDPDYLPALPRLAELYEKLGDPEEALE 233
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 68-255 6.87e-08

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 51.35  E-value: 6.87e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61557041  68 AQALMLKGKALNVTPDYSpEAEVLLSKAVKLEPELVEAWNQLGEVYWKKGDVAAAhtcfsgalthcknkvslqnlsmvLR 147
Cdd:COG4783   4 AEALYALAQALLLAGDYD-EAEALLEKALELDPDNPEAFALLGEILLQLGDLDEA-----------------------IV 59

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61557041 148 QLQTdsgdehsrhvmdsvrqaklAVQMDVLDGRSWYILGNAYLSLyfntGQNpkisQQALSAYAQAEKVDrkaSSNPDLH 227
Cdd:COG4783  60 LLHE-------------------ALELDPDEPEARLNLGLALLKA----GDY----DEALALLEKALKLD---PEHPEAY 109

                       170       180
                ....*....|....*....|....*...
gi 61557041 228 LNRATLHKYEESYGEALEGFSQAATLDP 255
Cdd:COG4783 110 LRLARAYRALGRPDEAIAALEKALELDP 137
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 2-260 1.27e-07

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 53.84  E-value: 1.27e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61557041   2 MADEEEEAKQVLQKLQELVDQLYCFRDSYFETHSVEDAGQKQQDVQEEMEKTLRQMEevLGSVQveaQALMLKGKALNVT 81
Cdd:COG3914  34 AAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLLQA--LGRYE---EALALYRRALALN 108

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61557041  82 PDYSP----------------EAEVLLSKAVKLEPELVEAWNQLGEVYWKKGDVAAAHTCFSGALTHCKNKVS-LQNLSM 144
Cdd:COG3914 109 PDNAEalfnlgnlllalgrleEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEaLNNLGN 188

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61557041 145 VLRQLqtdsgdehsRHVMDSVRQAKLAVQMDVldgrSWYILGNAYLSLYFNTGQNPKIsqQALSAYAQAEKVDRKASSNP 224
Cdd:COG3914 189 ALQDL---------GRLEEAIAAYRRALELDP----DNADAHSNLLFALRQACDWEVY--DRFEELLAALARGPSELSPF 253

                       250       260       270       280
                ....*....|....*....|....*....|....*....|....
gi 61557041 225 DLH--------LNRATLHKYEESYGEALEGFSQAATLDPAWPEP 260
Cdd:COG3914 254 ALLylpdddpaELLALARAWAQLVAAAAAPELPPPPNPRDPDRK 297
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 165-255 9.80e-07

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 47.69  E-value: 9.80e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61557041 165 VRQAKLAVQMDVLDGRSWYILGNAYLSLyfntgQNPkisQQALSAYAQAEKVDRKassNPDLHLNRATLHKYEESYGEAL 244
Cdd:COG4235   3 IARLRQALAANPNDAEGWLLLGRAYLRL-----GRY---DEALAAYEKALRLDPD---NADALLDLAEALLAAGDTEEAE 71

                        90
                ....*....|.
gi 61557041 245 EGFSQAATLDP 255
Cdd:COG4235  72 ELLERALALDP 82
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 46-130 4.22e-06

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 46.34  E-value: 4.22e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61557041  46 VQEEMEKTLRQMEEVLGSVQVEAQALMLKGKALNVTPDYsPEAEVLLSKAVKLEPELVEAWNQLGEVYWKKGDVAAAHTC 125
Cdd:COG4783  16 LAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDL-DEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALAL 94


                ....*
gi 61557041 126 FSGAL 130
Cdd:COG4783  95 LEKAL 99
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 87-150 1.29e-05

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 45.34  E-value: 1.29e-05
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 61557041  87 EAEVLLSKAVKLEPELVEAWNQLGEVYWKKGDVAAAHTCFSGALTHC-KNKVSLQNLSMVLRQLQ 150
Cdd:COG5010  72 ESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSpDNPNAYSNLAALLLSLG 136
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 87-267 3.71e-05

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 43.07  E-value: 3.71e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61557041  87 EAEVLLSKAVKLEPELVEAWNQLGEVYWKKGDVAAAHTCFSGALThcknkvslqnlsmvlrqlqtdsgdehsrhvmdsvr 166
Cdd:COG4235   1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALR----------------------------------- 45

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61557041 167 qaklavqmdvLDGRSWYILGNaYLSLYFNTGQNPkisqQALSAYAQAEKVDrkaSSNPDLHLNRATLHKYEESYGEALEG 246
Cdd:COG4235  46 ----------LDPDNADALLD-LAEALLAAGDTE----EAEELLERALALD---PDNPEALYLLGLAAFQQGDYAEAIAA 107

                       170       180
                ....*....|....*....|.
gi 61557041 247 FSQAATLDPAWPEPQQREQQL 267
Cdd:COG4235 108 WQKLLALLPADAPARLLEASI 128
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 68-130 2.28e-04

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 40.76  E-value: 2.28e-04
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 61557041  68 AQALMLKGKalnvtpdySPEAEVLLSKAVKLEPELVEAWNQLGEVYWKKGDVAAAHTCFSGAL 130
Cdd:COG4235  58 AEALLAAGD--------TEEAEELLERALALDPDNPEALYLLGLAAFQQGDYAEAIAAWQKLL 112
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
182-255 2.30e-04

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 42.21  E-value: 2.30e-04
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 61557041 182 WYILGNAYLSLYFntgqnpkiSQQALSAYAQAEKVDrkaSSNPDLHLNRATLHKYEESYGEALEGFSQAATLDP 255
Cdd:COG4785  76 YYERGVAYDSLGD--------YDLAIADFDQALELD---PDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDP 138
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 47-130 3.12e-04

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 40.56  E-value: 3.12e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61557041  47 QEEMEKTLRQMEEVLGSVQVEAQALMLKGKALNVTPDYSpEAEVLLSKAVKLEPELVEAWNQLGEVYWKKGDVAAAHTCF 126
Cdd:COG4783  51 LGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYD-EALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAAL 129


                ....
gi 61557041 127 SGAL 130
Cdd:COG4783 130 EKAL 133
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
47-130 4.71e-04

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 39.00  E-value: 4.71e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61557041  47 QEEMEKTLRQMEEVLGSVQVEAQALMLKGKALNVTPDYSpEAEVLlSKAVKLEPELVEAWNQLGEVYWKKGDVAAAHTCF 126
Cdd:COG3063   5 LGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYD-EAIAL-EKALKLDPNNAEALLNLAELLLELGDYDEALAYL 82


                ....
gi 61557041 127 SGAL 130
Cdd:COG3063  83 ERAL 86
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 68-130 5.48e-04

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 40.33  E-value: 5.48e-04
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 61557041  68 AQALMLKGKAlnvtpdysPEAEVLLSKAVKLEPELVEAWNQLGEVYWKKGDVAAAHTCFSGAL 130
Cdd:COG5010  95 ALLYSRSGDK--------DEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRAL 149
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
67-130 5.89e-04

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 41.05  E-value: 5.89e-04
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 61557041  67 EAQALMLKGKALNVTPDYSpEAEVLLSKAVKLEPELVEAWNQLGEVYWKKGDVAAAHTCFSGAL 130
Cdd:COG4785  72 LAQLYYERGVAYDSLGDYD-LAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRAL 134
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 5-150 8.84e-04

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 40.87  E-value: 8.84e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61557041   5 EEEEAKQVLQKLQELVD---QLYCfrdsyfethsvEDAGQKQQdvQEEMEKTLRQMEEVLGSVQVEAQALMLKGKALNVT 81
Cdd:COG2956 125 DWEKAIEVLERLLKLGPenaHAYC-----------ELAELYLE--QGDYDEAIEALEKALKLDPDCARALLLLAELYLEQ 191

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 61557041  82 PDYsPEAEVLLSKAVKLEPELVEAWNQLGEVYWKKGDVAAAHTCFSGALTHCKNKVSLQNLSMVLRQLQ 150
Cdd:COG2956 192 GDY-EEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSDDLLLALADLLERKE 259
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 204-280 1.26e-03

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 41.13  E-value: 1.26e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61557041 204 QQALSAYAQAEKVDRKA----SSNPDLHLNRATLHKYEESYGEALEGFSQAATLDPAWPEPQQREQQLLEFLSRLTNLLA 279
Cdd:COG3914  88 LQALGRYEEALALYRRAlalnPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIA 167


                .
gi 61557041 280 S 280
Cdd:COG3914 168 A 168
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 69-135 1.60e-03

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 40.30  E-value: 1.60e-03
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 61557041  69 QALMLKGKALNVTPDYSpEAEVLLSKAVKLEPELVEAWNQLGEVYWKKGDVAAAHTCFSGALTHCKN 135
Cdd:cd24142   1 DELLEKAEELLDQGNFE-LALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDPD 66
TPR_11 pfam13414
TPR repeat;
86-117 2.66e-03

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 35.53  E-value: 2.66e-03
                          10        20        30
                  ....*....|....*....|....*....|..
gi 61557041    86 PEAEVLLSKAVKLEPELVEAWNQLGEVYWKKG 117
Cdd:pfam13414  11 EEAIEAYKKALKLDPDNPEAYYNLGLAYYKLG 42
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 139-274 4.22e-03

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 37.63  E-value: 4.22e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61557041 139 LQNLSMVLRQLQTDSGDEHSRHVMDSVRQAKLAVQMDVLDGRSWYILGNAYLSLYFNTGQNpkisQQALSAYAQAEKVDR 218
Cdd:COG5010  10 LPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDF----EESLALLEQALQLDP 85

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*.
gi 61557041 219 KassNPDLHLNRATLHKYEESYGEALEGFSQAATLDPAWPEPQQREQQLLEFLSRL 274
Cdd:COG5010  86 N---NPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQD 138
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 171-274 4.84e-03

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 37.48  E-value: 4.84e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61557041 171 AVQMDVLDGRSWYILGNaylsLYFNTGQNpkisQQALSAYAQAEKVDRKassNPDLHLNRATLHKYEESYGEALEGFSQA 250
Cdd:COG4783  30 ALELDPDNPEAFALLGE----ILLQLGDL----DEAIVLLHEALELDPD---EPEARLNLGLALLKAGDYDEALALLEKA 98

                        90       100
                ....*....|....*....|....
gi 61557041 251 ATLDPAWPEPQQREQQLLEFLSRL 274
Cdd:COG4783  99 LKLDPEHPEAYLRLARAYRALGRP 122
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 163-262 7.70e-03

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 38.82  E-value: 7.70e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61557041 163 DSVRQAKLAVQMDVLDGRSWYILGNAYLSLyfntGQnpkiSQQALSAYAQAEKVDrkaSSNPDLHLNRATLHKYEESYGE 242
Cdd:COG3914  96 EALALYRRALALNPDNAEALFNLGNLLLAL----GR----LEEALAALRRALALN---PDFAEAYLNLGEALRRLGRLEE 164

                        90       100
                ....*....|....*....|
gi 61557041 243 ALEGFSQAATLDPAWPEPQQ 262
Cdd:COG3914 165 AIAALRRALELDPDNAEALN 184
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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