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Conserved domains on  [gi|58865548|ref|NP_001011986|]
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splicing factor 3A subunit 2 [Rattus norvegicus]

Protein Classification

PRP11 family protein( domain architecture ID 711366)

PRP11 family protein similar to Dictyostelium discoideum splicing factor 3A subunit 2 which is involved in pre-mRNA splicing as a component of the splicing factor SF3A complex that contributes to the assembly of the 17S U2 snRNP, and the subsequent assembly of the pre-spliceosome 'E' complex and the pre-catalytic spliceosome 'A' complex

CATH:  2.60.40.2690
Gene Ontology:  GO:0000398|GO:0008270|GO:0003676|GO:0000245

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRP11 super family cl25587
Splicing factor 3a, subunit 2 [RNA processing and modification];
1-217 1.57e-75

Splicing factor 3a, subunit 2 [RNA processing and modification];


The actual alignment was detected with superfamily member COG5246:

Pssm-ID: 227571 [Multi-domain]  Cd Length: 222  Bit Score: 236.11  E-value: 1.57e-75
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865548   1 MDFQHRPGGKTGSGGVASSSESNRDRRERLRQLALETIDINKDPYFMKNHLGSYECKLCLTLHNNEGSYLAHTQGKKHQT 80
Cdd:COG5246   1 MNYGGRGGSKTGGGGTASEIKKNKKRRSRQLLLEAYGQDLMDDPYLSKNHTGKYVCLLCKTKHLTEMSYVKHREGKKHKE 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865548  81 NLARRAAKEAKEAPA-QPA-----PEKVKVEVKKFVKIGRPGYKVTKQRDTEMGQQSLLFQIDYPEIAEGVMPRHRFMSA 154
Cdd:COG5246  81 NSSRRSEEKSSLGREnQTThdfrqQQKIIEAKQSLKRSGIPSYKVRSLVEPKGGRRGLGIQVNYEDDLAEEMPQYRIVSS 160

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 58865548 155 YEQRIEPPDRRWQYLLMAAEPYETIAFKvpsreIDKAEGKFW---THWNRETKQFFLQFHFKMEKP 217
Cdd:COG5246 161 LEQNVEEYDESFRYLVFACEPYENIAFK-----FENKEIDFLsiyEDWDAETGTYTLQFFFLEAGP 221
PRK12323 super family cl46901
DNA polymerase III subunit gamma/tau;
324-442 1.83e-09

DNA polymerase III subunit gamma/tau;


The actual alignment was detected with superfamily member PRK14951:

Pssm-ID: 481241 [Multi-domain]  Cd Length: 618  Bit Score: 59.73  E-value: 1.83e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865548  324 PPAPGVhPPAPGVHPPAPGVHPPAPgvHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPPSAGVHPQAPgVHPPAPAVHPQ 403
Cdd:PRK14951 380 TPARPE-AAAPAAAPVAQAAAAPAP--AAAPAAAASAPAAPPAAAPPAPVAAPAAAAPAAAPAAAPAA-VALAPAPPAQA 455

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 58865548  404 APGVHPPAPGIHPQAPGVHPQPPPGVHPAAPGVHPQPPG 442
Cdd:PRK14951 456 APETVAIPVRVAPEPAVASAAPAPAAAPAAARLTPTEEG 494
 
Name Accession Description Interval E-value
PRP11 COG5246
Splicing factor 3a, subunit 2 [RNA processing and modification];
1-217 1.57e-75

Splicing factor 3a, subunit 2 [RNA processing and modification];


Pssm-ID: 227571 [Multi-domain]  Cd Length: 222  Bit Score: 236.11  E-value: 1.57e-75
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865548   1 MDFQHRPGGKTGSGGVASSSESNRDRRERLRQLALETIDINKDPYFMKNHLGSYECKLCLTLHNNEGSYLAHTQGKKHQT 80
Cdd:COG5246   1 MNYGGRGGSKTGGGGTASEIKKNKKRRSRQLLLEAYGQDLMDDPYLSKNHTGKYVCLLCKTKHLTEMSYVKHREGKKHKE 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865548  81 NLARRAAKEAKEAPA-QPA-----PEKVKVEVKKFVKIGRPGYKVTKQRDTEMGQQSLLFQIDYPEIAEGVMPRHRFMSA 154
Cdd:COG5246  81 NSSRRSEEKSSLGREnQTThdfrqQQKIIEAKQSLKRSGIPSYKVRSLVEPKGGRRGLGIQVNYEDDLAEEMPQYRIVSS 160

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 58865548 155 YEQRIEPPDRRWQYLLMAAEPYETIAFKvpsreIDKAEGKFW---THWNRETKQFFLQFHFKMEKP 217
Cdd:COG5246 161 LEQNVEEYDESFRYLVFACEPYENIAFK-----FENKEIDFLsiyEDWDAETGTYTLQFFFLEAGP 221
SF3A2 pfam16835
Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11); SF3A2 is one of the components of the ...
 113-206 7.96e-58

Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11); SF3A2 is one of the components of the SF3a splicing factor complex of the mature U2 snRNP (small nuclear ribonucleoprotein particle). In yeast, SF3a shows a bifurcated assembly structure of three subunits, Prp9 (subunit 3), Prp11 (subunit 2) and Prp21 (subunit 1). with Prp21 wrapping around Prp11.


Pssm-ID: 435601  Cd Length: 95  Bit Score: 185.82  E-value: 7.96e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865548   113 GRPGYKVTKQRDTEMGQQSLLFQIDYPEIAEGVMPRHRFMSAYEQRIE-PPDRRWQYLLMAAEPYETIAFKVPSREIDKA 191
Cdd:pfam16835   1 GRPGYKVTKVRDPETGQLGLLFQVDYPEIAEGVKPRHRIMSAYEQKVEtPPDKNYQYLVIAAEPYETIAFKIPNREIDRL 80

                          90
                  ....*....|....*
gi 58865548   192 EGKFWTHWNRETKQF 206
Cdd:pfam16835  81 EGKFWTYWDPDTKEF 95
CactinC_cactus smart01050
Cactus-binding C-terminus of cactin protein; CactinC_cactus is the C-terminal 200 residues of ...
 112-218 5.58e-28

Cactus-binding C-terminus of cactin protein; CactinC_cactus is the C-terminal 200 residues of the cactin protein which are necessary for the association of cactin with IkappaB-cactus as one of the intracellular members of the Rel complex. The Rel (NF-kappaB) pathway is conserved in invertebrates and vertebrates. In mammals, it controls the activities of the immune and inflammatory response genes as well as viral genes, and is critical for cell growth and survival. In Drosophila, the Rel pathway functions in the innate cellular and humoral immune response, in muscle development, and in the establishment of dorsal-ventral polarity in the early embryo. Most members of the family also have a Cactin_mid domain further upstream.


Pssm-ID: 214996  Cd Length: 129  Bit Score: 107.82  E-value: 5.58e-28
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865548    112 IGRPGYKVTK---QRDTEMGQQSLLFQIDYPE-IAEGVMPRHRFMSAYEQriEPPDRRWQYLLM-AAEPYETIAFKVPSR 186
Cdd:smart01050  20 YDWNKYNQTHydnDNPPPKIVQGYKFNIFYPDlIDKGKAPRYRIESSFEI--EKPDDDTCLLRFsAGPPYEDIAFKIVNR 97

                           90       100       110
                   ....*....|....*....|....*....|...
gi 58865548    187 EIDKAE-GKFWTHWNRetKQFFLQFHFKMEKPP 218
Cdd:smart01050  98 EWDYSHrGGFKSSFDN--GILQLQFNFKKTRYR 128
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 324-442 1.83e-09

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 59.73  E-value: 1.83e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865548  324 PPAPGVhPPAPGVHPPAPGVHPPAPgvHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPPSAGVHPQAPgVHPPAPAVHPQ 403
Cdd:PRK14951 380 TPARPE-AAAPAAAPVAQAAAAPAP--AAAPAAAASAPAAPPAAAPPAPVAAPAAAAPAAAPAAAPAA-VALAPAPPAQA 455

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 58865548  404 APGVHPPAPGIHPQAPGVHPQPPPGVHPAAPGVHPQPPG 442
Cdd:PRK14951 456 APETVAIPVRVAPEPAVASAAPAPAAAPAAARLTPTEEG 494
PAT1 pfam09770
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ...
 326-444 1.29e-06

Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.


Pssm-ID: 401645 [Multi-domain]  Cd Length: 846  Bit Score: 51.19  E-value: 1.29e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865548   326 APGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPPSAGVHPQAPGVHPPAPAVHPQAP 405
Cdd:pfam09770 207 AKKPAQQPAPAPAQPPAAPPAQQAQQQQQFPPQIQQQQQPQQQPQQPQQHPGQGHPVTILQRPQSPQPDPAQPSIQPQAQ 286

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 58865548   406 GVH--PPAPGIHP----QAPGVHPQPPPGVHPAAPGVHPQPPGVH 444
Cdd:pfam09770 287 QFHqqPPPVPVQPtqilQNPNRLSAARVGYPQNPQPGVQPAPAHQ 331
SepH NF040712
septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces ...
 305-441 3.78e-04

septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces venezuelae, and homologs were identified in Mycobacterium smegmatis. SepH contains a N-terminal DUF3071 domain and a conserved C-terminal region. It binds directly to cell division protein FtsZ to stimulate the assembly of FtsZ protofilaments.


Pssm-ID: 468676 [Multi-domain]  Cd Length: 346  Bit Score: 42.45  E-value: 3.78e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865548  305 APGVHPPAPVVHPPTSGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGvhPPAPGVHPPAPGVHPPPSA 384
Cdd:NF040712 200 ATVPRLAREPADARPEEVEPAPAAEGAPATDSDPAEAGTPDDLASARRRRAGVEQPEDE--PVGPGAAPAAEPDEATRDA 277

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 58865548  385 GVHPqAPGVHPPAPAVHPQAPGVHPPAPGIHPQA-PGVHPQPPPGVHPAAPGVHPQPP 441
Cdd:NF040712 278 GEPP-APGAAETPEAAEPPAPAPAAPAAPAAPEAeEPARPEPPPAPKPKRRRRRASVP 334
 
Name Accession Description Interval E-value
PRP11 COG5246
Splicing factor 3a, subunit 2 [RNA processing and modification];
1-217 1.57e-75

Splicing factor 3a, subunit 2 [RNA processing and modification];


Pssm-ID: 227571 [Multi-domain]  Cd Length: 222  Bit Score: 236.11  E-value: 1.57e-75
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865548   1 MDFQHRPGGKTGSGGVASSSESNRDRRERLRQLALETIDINKDPYFMKNHLGSYECKLCLTLHNNEGSYLAHTQGKKHQT 80
Cdd:COG5246   1 MNYGGRGGSKTGGGGTASEIKKNKKRRSRQLLLEAYGQDLMDDPYLSKNHTGKYVCLLCKTKHLTEMSYVKHREGKKHKE 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865548  81 NLARRAAKEAKEAPA-QPA-----PEKVKVEVKKFVKIGRPGYKVTKQRDTEMGQQSLLFQIDYPEIAEGVMPRHRFMSA 154
Cdd:COG5246  81 NSSRRSEEKSSLGREnQTThdfrqQQKIIEAKQSLKRSGIPSYKVRSLVEPKGGRRGLGIQVNYEDDLAEEMPQYRIVSS 160

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 58865548 155 YEQRIEPPDRRWQYLLMAAEPYETIAFKvpsreIDKAEGKFW---THWNRETKQFFLQFHFKMEKP 217
Cdd:COG5246 161 LEQNVEEYDESFRYLVFACEPYENIAFK-----FENKEIDFLsiyEDWDAETGTYTLQFFFLEAGP 221
SF3A2 pfam16835
Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11); SF3A2 is one of the components of the ...
 113-206 7.96e-58

Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11); SF3A2 is one of the components of the SF3a splicing factor complex of the mature U2 snRNP (small nuclear ribonucleoprotein particle). In yeast, SF3a shows a bifurcated assembly structure of three subunits, Prp9 (subunit 3), Prp11 (subunit 2) and Prp21 (subunit 1). with Prp21 wrapping around Prp11.


Pssm-ID: 435601  Cd Length: 95  Bit Score: 185.82  E-value: 7.96e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865548   113 GRPGYKVTKQRDTEMGQQSLLFQIDYPEIAEGVMPRHRFMSAYEQRIE-PPDRRWQYLLMAAEPYETIAFKVPSREIDKA 191
Cdd:pfam16835   1 GRPGYKVTKVRDPETGQLGLLFQVDYPEIAEGVKPRHRIMSAYEQKVEtPPDKNYQYLVIAAEPYETIAFKIPNREIDRL 80

                          90
                  ....*....|....*
gi 58865548   192 EGKFWTHWNRETKQF 206
Cdd:pfam16835  81 EGKFWTYWDPDTKEF 95
CactinC_cactus smart01050
Cactus-binding C-terminus of cactin protein; CactinC_cactus is the C-terminal 200 residues of ...
 112-218 5.58e-28

Cactus-binding C-terminus of cactin protein; CactinC_cactus is the C-terminal 200 residues of the cactin protein which are necessary for the association of cactin with IkappaB-cactus as one of the intracellular members of the Rel complex. The Rel (NF-kappaB) pathway is conserved in invertebrates and vertebrates. In mammals, it controls the activities of the immune and inflammatory response genes as well as viral genes, and is critical for cell growth and survival. In Drosophila, the Rel pathway functions in the innate cellular and humoral immune response, in muscle development, and in the establishment of dorsal-ventral polarity in the early embryo. Most members of the family also have a Cactin_mid domain further upstream.


Pssm-ID: 214996  Cd Length: 129  Bit Score: 107.82  E-value: 5.58e-28
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865548    112 IGRPGYKVTK---QRDTEMGQQSLLFQIDYPE-IAEGVMPRHRFMSAYEQriEPPDRRWQYLLM-AAEPYETIAFKVPSR 186
Cdd:smart01050  20 YDWNKYNQTHydnDNPPPKIVQGYKFNIFYPDlIDKGKAPRYRIESSFEI--EKPDDDTCLLRFsAGPPYEDIAFKIVNR 97

                           90       100       110
                   ....*....|....*....|....*....|...
gi 58865548    187 EIDKAE-GKFWTHWNRetKQFFLQFHFKMEKPP 218
Cdd:smart01050  98 EWDYSHrGGFKSSFDN--GILQLQFNFKKTRYR 128
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 324-442 1.83e-09

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 59.73  E-value: 1.83e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865548  324 PPAPGVhPPAPGVHPPAPGVHPPAPgvHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPPSAGVHPQAPgVHPPAPAVHPQ 403
Cdd:PRK14951 380 TPARPE-AAAPAAAPVAQAAAAPAP--AAAPAAAASAPAAPPAAAPPAPVAAPAAAAPAAAPAAAPAA-VALAPAPPAQA 455

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 58865548  404 APGVHPPAPGIHPQAPGVHPQPPPGVHPAAPGVHPQPPG 442
Cdd:PRK14951 456 APETVAIPVRVAPEPAVASAAPAPAAAPAAARLTPTEEG 494
ZnF_U1 smart00451
U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ...
 52-85 1.53e-08

U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ribonucleoprotein C and other RNA-binding proteins.


Pssm-ID: 197732 [Multi-domain]  Cd Length: 35  Bit Score: 50.33  E-value: 1.53e-08
                           10        20        30
                   ....*....|....*....|....*....|....
gi 58865548     52 GSYECKLCLTLHNNEGSYLAHTQGKKHQTNLARR 85
Cdd:smart00451   2 GGFYCKLCNVTFTDEISVEAHLKGKKHKKNVKKR 35
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 319-442 1.35e-07

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 54.22  E-value: 1.35e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865548  319 TSGVHPPAPGVHPPAPGVhPPAPGVHPPAPGVHPPAPgvhPPAPGVHPPAPGVHPPAPGVHPPPSAGVHPQAPGVHPPAP 398
Cdd:PRK07764 387 VAGGAGAPAAAAPSAAAA-APAAAPAPAAAAPAAAAA---PAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPAAAP 462

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 58865548  399 AVHPqAPGVHPPAPGIHPQAPGVHPQPPPGVHPAAPGVHPQPPG 442
Cdd:PRK07764 463 SAQP-APAPAAAPEPTAAPAPAPPAAPAPAAAPAAPAAPAAPAG 505
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 304-441 2.89e-07

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 53.07  E-value: 2.89e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865548  304 PAPGVHPPAPVVHPPTSGVHPPAPGVHPPAPGvHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPPS 383
Cdd:PRK07764 588 VGPAPGAAGGEGPPAPASSGPPEEAARPAAPA-APAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGG 666

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 58865548  384 AGVHPQAPGVHPPAPAVHPQAPGVHPPAPGIHPQ-APGVHPQPPPGVHPAAPGVHPQPP 441
Cdd:PRK07764 667 DGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQpAPAPAATPPAGQADDPAAQPPQAA 725
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 303-441 4.81e-07

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 52.30  E-value: 4.81e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865548  303 PPAPGVHPPAPVVHPPTSGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAP-GVHPPAPGVHPPAPGVHPPAPGVHPP 381
Cdd:PRK07764 633 AAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPaPAAPAAPAGAAPAQPAPAPAATPPAG 712

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 58865548  382 PSAGVHPQAPGV----HPPAPAVHPQAP-GVHPPAPGIHPQAPGVHPQPPPGVHPAAPGVHPQPP 441
Cdd:PRK07764 713 QADDPAAQPPQAaqgaSAPSPAADDPVPlPPEPDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPPS 777
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 324-441 8.72e-07

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 51.25  E-value: 8.72e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865548  324 PPAPGVHPPAPGVhPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPgvhppAPGVHPPPSAGVHPQAPGVHPPAP--AVH 401
Cdd:PRK14951 373 AAPAEKKTPARPE-AAAPAAAPVAQAAAAPAPAAAPAAAASAPAAP-----PAAAPPAPVAAPAAAAPAAAPAAApaAVA 446

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 58865548  402 PQAPGVHPPAPGIHPQAPGVHPQPPPGVHPAAPGVHPQPP 441
Cdd:PRK14951 447 LAPAPPAQAAPETVAIPVRVAPEPAVASAAPAPAAAPAAA 486
PAT1 pfam09770
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ...
 326-444 1.29e-06

Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.


Pssm-ID: 401645 [Multi-domain]  Cd Length: 846  Bit Score: 51.19  E-value: 1.29e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865548   326 APGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPPSAGVHPQAPGVHPPAPAVHPQAP 405
Cdd:pfam09770 207 AKKPAQQPAPAPAQPPAAPPAQQAQQQQQFPPQIQQQQQPQQQPQQPQQHPGQGHPVTILQRPQSPQPDPAQPSIQPQAQ 286

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 58865548   406 GVH--PPAPGIHP----QAPGVHPQPPPGVHPAAPGVHPQPPGVH 444
Cdd:pfam09770 287 QFHqqPPPVPVQPtqilQNPNRLSAARVGYPQNPQPGVQPAPAHQ 331
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 319-439 1.78e-06

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 50.69  E-value: 1.78e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865548   319 TSGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPPSAGVHPqAPGVHPPAP 398
Cdd:pfam05109 482 TSGASPVTPSPSPRDNGTESKAPDMTSPTSAVTTPTPNATSPTPAVTTPTPNATSPTLGKTSPTSAVTTP-TPNATSPTP 560

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 58865548   399 AVHPQAPGVHPPAPGIHPQAPGVHPQPPPGVHPAAPGVHPQ 439
Cdd:pfam05109 561 AVTTPTPNATIPTLGKTSPTSAVTTPTPNATSPTVGETSPQ 601
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 299-426 2.37e-06

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 50.10  E-value: 2.37e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865548  299 SGVHPPAPGVHPPAPVVHPPTSGVHPPAPGVHPPAPgvHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGV 378
Cdd:PRK14951 368 AAAEAAAPAEKKTPARPEAAAPAAAPVAQAAAAPAP--AAAPAAAASAPAAPPAAAPPAPVAAPAAAAPAAAPAAAPAAV 445

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 58865548  379 HPPPSAGVHPQAPGVHPPAPAVHPQAPGVHPPAPGIHPQAPGVHPQPP 426
Cdd:PRK14951 446 ALAPAPPAQAAPETVAIPVRVAPEPAVASAAPAPAAAPAAARLTPTEE 493
zf-met pfam12874
Zinc-finger of C2H2 type; This is a zinc-finger domain with the CxxCx(12)Hx(6)H motif, found ...
 54-78 3.02e-06

Zinc-finger of C2H2 type; This is a zinc-finger domain with the CxxCx(12)Hx(6)H motif, found in multiple copies in a wide range of proteins from plants to metazoans. Some member proteins, particularly those from plants, are annotated as being RNA-binding.


Pssm-ID: 463736 [Multi-domain]  Cd Length: 25  Bit Score: 43.64  E-value: 3.02e-06
                          10        20
                  ....*....|....*....|....*
gi 58865548    54 YECKLCLTLHNNEGSYLAHTQGKKH 78
Cdd:pfam12874   1 FYCELCNVTFNSESQLKSHLQGKKH 25
PTZ00436 PTZ00436
60S ribosomal protein L19-like protein; Provisional
 304-418 3.82e-06

60S ribosomal protein L19-like protein; Provisional


Pssm-ID: 185616 [Multi-domain]  Cd Length: 357  Bit Score: 48.79  E-value: 3.82e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865548  304 PAPGVHPPAPVVHPPTSGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPPS 383
Cdd:PTZ00436 229 PAKAAAPPAKAAAAPAKAAAAPAKAAAPPAKAAAPPAKAAAPPAKAAAPPAKAAAPPAKAAAPPAKAAAAPAKAAAAPAK 308

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 58865548  384 AGVHPqAPGVHPPAPAVHPQAPGVHPPAPGIHPQA 418
Cdd:PTZ00436 309 AAAAP-AKAAAPPAKAAAPPAKAATPPAKAAAPPA 342
PTZ00436 PTZ00436
60S ribosomal protein L19-like protein; Provisional
 304-431 8.77e-06

60S ribosomal protein L19-like protein; Provisional


Pssm-ID: 185616 [Multi-domain]  Cd Length: 357  Bit Score: 47.64  E-value: 8.77e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865548  304 PAPGVHPPAPVVHPPTSGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPPS 383
Cdd:PTZ00436 222 PAKAAAAPAKAAAPPAKAAAAPAKAAAAPAKAAAPPAKAAAPPAKAAAPPAKAAAPPAKAAAPPAKAAAPPAKAAAAPAK 301

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 58865548  384 AGVHPqAPGVHPPAPAVHPQAPGVHPPAPGIHPQAPGVHPQPPPGVHP 431
Cdd:PTZ00436 302 AAAAP-AKAAAAPAKAAAPPAKAAAPPAKAATPPAKAAAPPAKAAAAP 348
PAT1 pfam09770
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ...
 322-440 1.12e-05

Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.


Pssm-ID: 401645 [Multi-domain]  Cd Length: 846  Bit Score: 48.11  E-value: 1.12e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865548   322 VHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPPSAGVHPQAPGVHPPAPAVH 401
Cdd:pfam09770 217 APAQPPAAPPAQQAQQQQQFPPQIQQQQQPQQQPQQPQQHPGQGHPVTILQRPQSPQPDPAQPSIQPQAQQFHQQPPPVP 296

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 58865548   402 P------QAPGVHPPAPGIHPQ--APGVHPQPPPGVHPAAPG--------VHPQP 440
Cdd:pfam09770 297 VqptqilQNPNRLSAARVGYPQnpQPGVQPAPAHQAHRQQGSfgrqapiiTHPQQ 351
PTZ00436 PTZ00436
60S ribosomal protein L19-like protein; Provisional
 303-411 1.39e-05

60S ribosomal protein L19-like protein; Provisional


Pssm-ID: 185616 [Multi-domain]  Cd Length: 357  Bit Score: 47.25  E-value: 1.39e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865548  303 PPAPGVHPPAPVVHPPTSGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPP 382
Cdd:PTZ00436 235 PPAKAAAAPAKAAAAPAKAAAPPAKAAAPPAKAAAPPAKAAAPPAKAAAPPAKAAAPPAKAAAAPAKAAAAPAKAAAAPA 314

                         90       100
                 ....*....|....*....|....*....
gi 58865548  383 SAGVHPqAPGVHPPAPAVHPQAPGVHPPA 411
Cdd:PTZ00436 315 KAAAPP-AKAAAPPAKAATPPAKAAAPPA 342
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 324-434 1.55e-05

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 47.67  E-value: 1.55e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865548  324 PPAPGVHPPAPGVHPPAPgvhPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPPSAGVHPQAPGVHPPAPAVHPQ 403
Cdd:PRK07764 405 APAAAPAPAAAAPAAAAA---PAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPAAAPSAQPAPAPAAAPEPTAAPA 481

                         90       100       110
                 ....*....|....*....|....*....|.
gi 58865548  404 APGVHPPAPGIHPQAPGVHPQPPPGVHPAAP 434
Cdd:PRK07764 482 PAPPAAPAPAAAPAAPAAPAAPAGADDAATL 512
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 324-442 3.18e-05

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 46.52  E-value: 3.18e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865548  324 PPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVhppapgvhppPSAGVHPQAPGVHPPAPAVHPQ 403
Cdd:PRK07764 600 PPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGV----------AAPEHHPKHVAVPDASDGGDGW 669

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 58865548  404 APGVHPPAPGIHPQAPGVHPQPPPGVHPAAPGVHPQPPG 442
Cdd:PRK07764 670 PAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAAT 708
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 303-441 5.25e-05

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 45.75  E-value: 5.25e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865548  303 PPAPGVHPPAPVVHPPTSGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPP 382
Cdd:PRK07764 612 AARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPA 691

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 58865548  383 SAGVHPQApgvhPPAPAVHPQAPGVHPPAPGIHPQAPGVHPQPPPGVHPAAPGVHPQPP 441
Cdd:PRK07764 692 APAGAAPA----QPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPPEPD 746
PTZ00436 PTZ00436
60S ribosomal protein L19-like protein; Provisional
 324-442 8.68e-05

60S ribosomal protein L19-like protein; Provisional


Pssm-ID: 185616 [Multi-domain]  Cd Length: 357  Bit Score: 44.56  E-value: 8.68e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865548  324 PPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPPSAGVhpqAPGVHPPAPAVHPQ 403
Cdd:PTZ00436 235 PPAKAAAAPAKAAAAPAKAAAPPAKAAAPPAKAAAPPAKAAAPPAKAAAPPAKAAAPPAKAAA---APAKAAAAPAKAAA 311

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 58865548  404 APGVHPPAPGIHPQAPGVHPQPPPGVHPAAPGVHPQPPG 442
Cdd:PTZ00436 312 APAKAAAPPAKAAAPPAKAATPPAKAAAPPAKAAAAPVG 350
PTZ00436 PTZ00436
60S ribosomal protein L19-like protein; Provisional
 325-438 1.13e-04

60S ribosomal protein L19-like protein; Provisional


Pssm-ID: 185616 [Multi-domain]  Cd Length: 357  Bit Score: 44.17  E-value: 1.13e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865548  325 PAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPPSAGvHPQAPGVHPPAPAVHPQA 404
Cdd:PTZ00436 229 PAKAAAPPAKAAAAPAKAAAAPAKAAAPPAKAAAPPAKAAAPPAKAAAPPAKAAAPPAKAA-APPAKAAAAPAKAAAAPA 307

                         90       100       110
                 ....*....|....*....|....*....|....
gi 58865548  405 PGVHPPAPGIHPQAPGVHPQPPPGVHPAAPGVHP 438
Cdd:PTZ00436 308 KAAAAPAKAAAPPAKAAAPPAKAATPPAKAAAPP 341
PTZ00436 PTZ00436
60S ribosomal protein L19-like protein; Provisional
 325-438 2.04e-04

60S ribosomal protein L19-like protein; Provisional


Pssm-ID: 185616 [Multi-domain]  Cd Length: 357  Bit Score: 43.40  E-value: 2.04e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865548  325 PAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPPSAGVHPqAPGVHPPAPAVHPQA 404
Cdd:PTZ00436 222 PAKAAAAPAKAAAPPAKAAAAPAKAAAAPAKAAAPPAKAAAPPAKAAAPPAKAAAPPAKAAAPP-AKAAAPPAKAAAAPA 300

                         90       100       110
                 ....*....|....*....|....*....|....
gi 58865548  405 PGVHPPAPGIHPQAPGVHPQPPPGVHPAAPGVHP 438
Cdd:PTZ00436 301 KAAAAPAKAAAAPAKAAAPPAKAAAPPAKAATPP 334
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
324-434 2.77e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 43.33  E-value: 2.77e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865548  324 PPAPGVHPPAPGVHPPAPGVhPPAPGVHPPApgvhpPAPGVHPPAPGVHPPAPGVHPPPSAGVHPQAPGVHP-PAPAVHP 402
Cdd:PRK12323 391 APAAAAPAPAAPPAAPAAAP-AAAAAARAVA-----AAPARRSPAPEALAAARQASARGPGGAPAPAPAPAAaPAAAARP 464

                         90       100       110
                 ....*....|....*....|....*....|..
gi 58865548  403 QAPGVHPPAPGIHPQAPGVHPQPPPGVHPAAP 434
Cdd:PRK12323 465 AAAGPRPVAAAAAAAPARAAPAAAPAPADDDP 496
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 303-406 2.96e-04

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 43.16  E-value: 2.96e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865548  303 PPAPGVHPPAPVVHPPTSGVHPPAPGVHPPAPGVHPPAPG--------VHPPAPGVHPPAPgVHPPAPGVHPPAPGVHPP 374
Cdd:PRK14951 384 PEAAAPAAAPVAQAAAAPAPAAAPAAAASAPAAPPAAAPPapvaapaaAAPAAAPAAAPAA-VALAPAPPAQAAPETVAI 462

                         90       100       110
                 ....*....|....*....|....*....|..
gi 58865548  375 APGVHPPPSAGVHPQAPGVHPPAPAVHPQAPG 406
Cdd:PRK14951 463 PVRVAPEPAVASAAPAPAAAPAAARLTPTEEG 494
PHA03247 PHA03247
large tegument protein UL36; Provisional
 324-442 3.51e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 43.39  E-value: 3.51e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865548   324 PPAPGVHPPAPgvHPPAPgvHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPPSAGVHPQAPGVHPPAPAVHPQ 403
Cdd:PHA03247 2611 PAPPSPLPPDT--HAPDP--PPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRR 2686

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 58865548   404 A--PGVHPPAPGIHPQAPGVHPQPPPgvHPAAPGVhPQPPG 442
Cdd:PHA03247 2687 AarPTVGSLTSLADPPPPPPTPEPAP--HALVSAT-PLPPG 2724
SepH NF040712
septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces ...
 305-441 3.78e-04

septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces venezuelae, and homologs were identified in Mycobacterium smegmatis. SepH contains a N-terminal DUF3071 domain and a conserved C-terminal region. It binds directly to cell division protein FtsZ to stimulate the assembly of FtsZ protofilaments.


Pssm-ID: 468676 [Multi-domain]  Cd Length: 346  Bit Score: 42.45  E-value: 3.78e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865548  305 APGVHPPAPVVHPPTSGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGvhPPAPGVHPPAPGVHPPPSA 384
Cdd:NF040712 200 ATVPRLAREPADARPEEVEPAPAAEGAPATDSDPAEAGTPDDLASARRRRAGVEQPEDE--PVGPGAAPAAEPDEATRDA 277

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 58865548  385 GVHPqAPGVHPPAPAVHPQAPGVHPPAPGIHPQA-PGVHPQPPPGVHPAAPGVHPQPP 441
Cdd:NF040712 278 GEPP-APGAAETPEAAEPPAPAPAAPAAPAAPEAeEPARPEPPPAPKPKRRRRRASVP 334
PRK07994 PRK07994
DNA polymerase III subunits gamma and tau; Validated
 324-444 5.98e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236138 [Multi-domain]  Cd Length: 647  Bit Score: 42.16  E-value: 5.98e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865548  324 PPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPPSAGVHPQAPGVHPPAPAVHPQ 403
Cdd:PRK07994 376 APAASAQATAAPTAAVAPPQAPAVPPPPASAPQQAPAVPLPETTSQLLAARQQLQRAQGATKAKKSEPAAASRARPVNSA 455

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 58865548  404 APGVHPPAPGIHPQAPGVHPQPPPGVHPAAPGVHPQPPGVH 444
Cdd:PRK07994 456 LERLASVRPAPSALEKAPAKKEAYRWKATNPVEVKKEPVAT 496
PHA02030 PHA02030
hypothetical protein
 333-421 1.03e-03

hypothetical protein


Pssm-ID: 222843 [Multi-domain]  Cd Length: 336  Bit Score: 41.12  E-value: 1.03e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865548  333 APGVHPPAPGVHPPAPGVHPpAPGVHPPAPGVHPPAPGVhppapgvHPPPSAGVHPQAPGVHPPAPAVHPQAPGVhppaP 412
Cdd:PHA02030 261 AAGSNLPAVPNVAADAGSAA-APAVPAAAAAVAQAAPSV-------PQVPNVAVLPDVPQVAPVAAPAAPEVPAV----P 328


                 ....*....
gi 58865548  413 GIhPQAPGV 421
Cdd:PHA02030 329 VV-PAAPQV 336
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 325-441 1.32e-03

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 41.61  E-value: 1.32e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865548   325 PAPGVHPPAPGVHPPAPGVHP-----PAPGVHPPAPgVHPPAPGVHPPAPGVHPPAPGVHPPPSAGVHPQAPGVHPPAPA 399
Cdd:PRK10263  336 PVEPVTQTPPVASVDVPPAQPtvawqPVPGPQTGEP-VIAPAPEGYPQQSQYAQPAVQYNEPLQQPVQPQQPYYAPAAEQ 414

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 58865548   400 VhPQAPGVHPpapgiHPQAPGVHPQPPPGVHPAAPGVHPQPP 441
Cdd:PRK10263  415 P-AQQPYYAP-----APEQPAQQPYYAPAPEQPVAGNAWQAE 450
PRK07994 PRK07994
DNA polymerase III subunits gamma and tau; Validated
 351-441 1.73e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236138 [Multi-domain]  Cd Length: 647  Bit Score: 41.00  E-value: 1.73e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865548  351 HPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPPSAGVHPQAPGVHPPAPAVHPQAPGVHPPAPGIHPQAPGVHPQPPPGVH 430
Cdd:PRK07994 360 HPAAPLPEPEVPPQSAAPAASAQATAAPTAAVAPPQAPAVPPPPASAPQQAPAVPLPETTSQLLAARQQLQRAQGATKAK 439

                         90
                 ....*....|.
gi 58865548  431 PAAPGVHPQPP 441
Cdd:PRK07994 440 KSEPAAASRAR 450
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 298-404 1.98e-03

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 40.67  E-value: 1.98e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865548   298 TSGVHPPAPGVHPpapvvhpptsgvhpPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPG 377
Cdd:pfam05109 510 TSAVTTPTPNATS--------------PTPAVTTPTPNATSPTLGKTSPTSAVTTPTPNATSPTPAVTTPTPNATIPTLG 575

                          90       100
                  ....*....|....*....|....*..
gi 58865548   378 VHPPPSAGVHPQAPGVHPPAPAVHPQA 404
Cdd:pfam05109 576 KTSPTSAVTTPTPNATSPTVGETSPQA 602
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 300-413 3.37e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 39.97  E-value: 3.37e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865548  300 GVHPPAPGVHPPAPVVHPPTSGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVH 379
Cdd:PRK07764 388 AGGAGAPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPAAAPSAQPA 467

                         90       100       110
                 ....*....|....*....|....*....|....*...
gi 58865548  380 PPPSAGVHPQAP----GVHPPAPAVHPQAPGVHPPAPG 413
Cdd:PRK07764 468 PAPAAAPEPTAApapaPPAAPAPAAAPAAPAAPAAPAG 505
PHA02030 PHA02030
hypothetical protein
 340-436 6.47e-03

hypothetical protein


Pssm-ID: 222843 [Multi-domain]  Cd Length: 336  Bit Score: 38.81  E-value: 6.47e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865548  340 APGVHPPAPGVHPPAPGVHPpAPGVHPPAPGVhppapgvhpppsAGVHPQAPGVhpPAPAVHPQAPGVHPPAPGIHPQAP 419
Cdd:PHA02030 261 AAGSNLPAVPNVAADAGSAA-APAVPAAAAAV------------AQAAPSVPQV--PNVAVLPDVPQVAPVAAPAAPEVP 325

                         90
                 ....*....|....*..
gi 58865548  420 GVhpqppPGVhPAAPGV 436
Cdd:PHA02030 326 AV-----PVV-PAAPQV 336
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 271-440 8.25e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 38.81  E-value: 8.25e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865548  271 PSGPPGPPQMPPPAPGVHPPApvvhpptsgvHPPAPGVHPPAPVVHPPTSGVHPPAPGVHPPAPGVHPPAPGVHP-PAPG 349
Cdd:PRK07764 635 APAEASAAPAPGVAAPEHHPK----------HVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAqPAPA 704

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865548  350 VHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPPSAGVH--PQAPGVHPPAPAVHPQAPGVHPPAPGIHPQAPGVHPQPPP 427
Cdd:PRK07764 705 PAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPpePDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPPSEEEE 784

                        170
                 ....*....|...
gi 58865548  428 GVHPAAPGVHPQP 440
Cdd:PRK07764 785 MAEDDAPSMDDED 797
PHA03247 PHA03247
large tegument protein UL36; Provisional
 319-440 9.51e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 38.77  E-value: 9.51e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865548   319 TSGVHPPAPGvHPPAPGVHPPAPGVhpPAPGVHPPAPGVHPPAPGVhpPAPGVHPPAPGVHPPPSAGVHPQAPG--VHPP 396
Cdd:PHA03247 2696 TSLADPPPPP-PTPEPAPHALVSAT--PLPPGPAAARQASPALPAA--PAPPAVPAGPATPGGPARPARPPTTAgpPAPA 2770

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 58865548   397 APAVHPQAPGVHPPAPGIHPQAPGVHPQPPPGVHPAAPGVHPQP 440
Cdd:PHA03247 2771 PPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAP 2814
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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