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Conserved domains on  [gi|57222296|ref|NP_001009448|]
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cadherin-19 [Rattus norvegicus]

Protein Classification

cadherin( domain architecture ID 10182681)

cadherin is a calcium-dependent cell adhesion protein that preferentially interacts with itself in a homophilic manner in connecting cells; it plays a crucial role in tissue morphogenesis and homeostasis

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 150-250 6.76e-27

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 105.09  E-value: 6.76e-27
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 57222296 150 PYEAIVPEMSPEGTFVIKVTANDADdptSGYHARILYNLEQGQP--YFSVEPTTGVIRISSKMDRELQDTYCVIIQAKDM 227
Cdd:cd11304   1 SYEVSVPENAPPGTVVLTVSATDPD---SGENGEVTYSIVSGNEdgLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDG 77

                        90       100
                ....*....|....*....|...
gi 57222296 228 LGQPgaLSGTTTISIKLSDINDN 250
Cdd:cd11304  78 GGPP--LSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 373-464 8.91e-23

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 93.15  E-value: 8.91e-23
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 57222296 373 YIFEIPEGKPYGTMVGTVSAVDPDR-RQSPMRYSLIG---SKMFDINGN-GTIVTTNLLDREVSAWYNLSVTATETYNVQ 447
Cdd:cd11304   2 YEVSVPENAPPGTVVLTVSATDPDSgENGEVTYSIVSgneDGLFSIDPStGEITTAKPLDREEQSSYTLTVTATDGGGPP 81

                        90
                ....*....|....*..
gi 57222296 448 QISSAHVYVQVLNINDH 464
Cdd:cd11304  82 LSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 259-364 4.47e-18

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 80.05  E-value: 4.47e-18
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 57222296 259 YRFTISESAPSGTTIGKIMAYDDDIGENAEMDYSI-EDDESQIFDIvidnETQEGIVILKKKVDFEHQNHYGIRVKVKNC 337
Cdd:cd11304   2 YEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIvSGNEDGLFSI----DPSTGEITTAKPLDREEQSSYTLTVTATDG 77

                        90       100
                ....*....|....*....|....*..
gi 57222296 338 HVdeelapaHVNASTTYIKVQVEDEDE 364
Cdd:cd11304  78 GG-------PPLSSTATVTITVLDVND 97
CADH_Y-type_LIR pfam01049
Cadherin, Y-type LIR-motif; LC3 Interacting Regions (LIRs), also known as ATG8-interacting ...
 704-763 7.43e-18

Cadherin, Y-type LIR-motif; LC3 Interacting Regions (LIRs), also known as ATG8-interacting motifs (AIMs), are short-linear motifs (SLiMs) of autophagy receptors and adaptor proteins that facilitates the selective recruitment of autophagy substrates to the autophagosome. LIRs are characterized by degenerated sequences with a four-residue core central sequence involved in ATG8-binding, with the W/Y/FxxL/I/V pattern. Based on the aromatic amino acid in position 1 they can be classified into W-type, Y-type and F-type. This entry includes three conserved LIR motifs of CADHs, which two are Y-type (YDxL/I) and one F-type (FKKL), while a fourth LIR (YGGV) is only present in CADH6 members. Cadherins (CADH) have a crucial role in epithelial-to-mesenchymal transition (EMT), involved in migration properties of tumour cells. CADH6 is an EMT marker in thyroid cancer that interacts with the ATG8 family members GABARAP, BNIP3 and BNIP3L restraining autophagy through LIR domains, a common feature among many cadherin family members.


:

Pssm-ID: 460041  Cd Length: 60  Bit Score: 77.96  E-value: 7.43e-18
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 57222296   704 ANTDSSAPPFDSLQTFAYEGTGSSAGSLSSLGSSVTDQEDDFDYLNDLGPCFKRLANMFG 763
Cdd:pfam01049   1 ADNDPSAPPYDSLQTYAYEGDGSSAGSLSSLESSTSDSDQDYDYLSDWGPRFKKLAELYG 60
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 49-142 2.00e-17

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 78.12  E-value: 2.00e-17
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 57222296  49 QFVVPEEMDTIQHVGRLR-SDLDNGNNS-FQYKLL-GTGDGSFSIDEKTGDIFAMQKLDREKQSLYILRAQVIDTTiGKA 125
Cdd:cd11304   3 EVSVPENAPPGTVVLTVSaTDPDSGENGeVTYSIVsGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGG-GPP 81

                        90
                ....*....|....*..
gi 57222296 126 VEPESEFVIRVSDVNDN 142
Cdd:cd11304  82 LSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 472-570 1.72e-10

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 58.48  E-value: 1.72e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 57222296 472 YETYVCENAESGEIIQTISAIDRDESIEDHHFYfnHSVEDTNNSSFILtdnQDNTAVILSNRagfSL-KEETVFYMIILI 550
Cdd:cd11304   2 YEVSVPENAPPGTVVLTVSATDPDSGENGEVTY--SIVSGNEDGLFSI---DPSTGEITTAK---PLdREEQSSYTLTVT 73

                        90       100
                ....*....|....*....|.
gi 57222296 551 A-DNGIPPLTSTNTLTIQVCD 570
Cdd:cd11304  74 AtDGGGPPLSSTATVTITVLD 94
 
Name Accession Description Interval E-value
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 150-250 6.76e-27

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 105.09  E-value: 6.76e-27
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 57222296 150 PYEAIVPEMSPEGTFVIKVTANDADdptSGYHARILYNLEQGQP--YFSVEPTTGVIRISSKMDRELQDTYCVIIQAKDM 227
Cdd:cd11304   1 SYEVSVPENAPPGTVVLTVSATDPD---SGENGEVTYSIVSGNEdgLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDG 77

                        90       100
                ....*....|....*....|...
gi 57222296 228 LGQPgaLSGTTTISIKLSDINDN 250
Cdd:cd11304  78 GGPP--LSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 373-464 8.91e-23

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 93.15  E-value: 8.91e-23
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 57222296 373 YIFEIPEGKPYGTMVGTVSAVDPDR-RQSPMRYSLIG---SKMFDINGN-GTIVTTNLLDREVSAWYNLSVTATETYNVQ 447
Cdd:cd11304   2 YEVSVPENAPPGTVVLTVSATDPDSgENGEVTYSIVSgneDGLFSIDPStGEITTAKPLDREEQSSYTLTVTATDGGGPP 81

                        90
                ....*....|....*..
gi 57222296 448 QISSAHVYVQVLNINDH 464
Cdd:cd11304  82 LSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 259-364 4.47e-18

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 80.05  E-value: 4.47e-18
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 57222296 259 YRFTISESAPSGTTIGKIMAYDDDIGENAEMDYSI-EDDESQIFDIvidnETQEGIVILKKKVDFEHQNHYGIRVKVKNC 337
Cdd:cd11304   2 YEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIvSGNEDGLFSI----DPSTGEITTAKPLDREEQSSYTLTVTATDG 77

                        90       100
                ....*....|....*....|....*..
gi 57222296 338 HVdeelapaHVNASTTYIKVQVEDEDE 364
Cdd:cd11304  78 GG-------PPLSSTATVTITVLDVND 97
CADH_Y-type_LIR pfam01049
Cadherin, Y-type LIR-motif; LC3 Interacting Regions (LIRs), also known as ATG8-interacting ...
 704-763 7.43e-18

Cadherin, Y-type LIR-motif; LC3 Interacting Regions (LIRs), also known as ATG8-interacting motifs (AIMs), are short-linear motifs (SLiMs) of autophagy receptors and adaptor proteins that facilitates the selective recruitment of autophagy substrates to the autophagosome. LIRs are characterized by degenerated sequences with a four-residue core central sequence involved in ATG8-binding, with the W/Y/FxxL/I/V pattern. Based on the aromatic amino acid in position 1 they can be classified into W-type, Y-type and F-type. This entry includes three conserved LIR motifs of CADHs, which two are Y-type (YDxL/I) and one F-type (FKKL), while a fourth LIR (YGGV) is only present in CADH6 members. Cadherins (CADH) have a crucial role in epithelial-to-mesenchymal transition (EMT), involved in migration properties of tumour cells. CADH6 is an EMT marker in thyroid cancer that interacts with the ATG8 family members GABARAP, BNIP3 and BNIP3L restraining autophagy through LIR domains, a common feature among many cadherin family members.


Pssm-ID: 460041  Cd Length: 60  Bit Score: 77.96  E-value: 7.43e-18
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 57222296   704 ANTDSSAPPFDSLQTFAYEGTGSSAGSLSSLGSSVTDQEDDFDYLNDLGPCFKRLANMFG 763
Cdd:pfam01049   1 ADNDPSAPPYDSLQTYAYEGDGSSAGSLSSLESSTSDSDQDYDYLSDWGPRFKKLAELYG 60
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 49-142 2.00e-17

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 78.12  E-value: 2.00e-17
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 57222296  49 QFVVPEEMDTIQHVGRLR-SDLDNGNNS-FQYKLL-GTGDGSFSIDEKTGDIFAMQKLDREKQSLYILRAQVIDTTiGKA 125
Cdd:cd11304   3 EVSVPENAPPGTVVLTVSaTDPDSGENGeVTYSIVsGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGG-GPP 81

                        90
                ....*....|....*..
gi 57222296 126 VEPESEFVIRVSDVNDN 142
Cdd:cd11304  82 LSSTATVTITVLDVNDN 98
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 169-252 3.67e-17

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 76.62  E-value: 3.67e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 57222296    169 TANDADDPTSGyhaRILYNLEQG--QPYFSVEPTTGVIRISSKMDRELQDTYCVIIQAKDMLGQPgaLSGTTTISIKLSD 246
Cdd:smart00112   1 SATDADSGENG---KVTYSILSGndDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPP--LSSTATVTITVLD 75


                   ....*.
gi 57222296    247 INDNKP 252
Cdd:smart00112  76 VNDNAP 81
Cadherin pfam00028
Cadherin domain;
151-244 2.65e-16

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 74.64  E-value: 2.65e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 57222296   151 YEAIVPEMSPEGTFVIKVTANDADDPTsgyHARILYNLEQGQPY--FSVEPTTGVIRISSKMDRELQDTYCVIIQAKDML 228
Cdd:pfam00028   1 YSASVPENAPVGTEVLTVTATDPDLGP---NGRIFYSILGGGPGgnFRIDPDTGDISTTKPLDRESIGEYELTVEATDSG 77

                          90
                  ....*....|....*.
gi 57222296   229 GQPgaLSGTTTISIKL 244
Cdd:pfam00028  78 GPP--LSSTATVTITV 91
Cadherin pfam00028
Cadherin domain;
373-459 2.61e-15

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 71.95  E-value: 2.61e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 57222296   373 YIFEIPEGKPYGTMVGTVSAVDPDR--RQSPmRYSLIG---SKMFDIN-GNGTIVTTNLLDREVSAWYNLSVTATETYNV 446
Cdd:pfam00028   1 YSASVPENAPVGTEVLTVTATDPDLgpNGRI-FYSILGggpGGNFRIDpDTGDISTTKPLDRESIGEYELTVEATDSGGP 79

                          90
                  ....*....|...
gi 57222296   447 QQISSAHVYVQVL 459
Cdd:pfam00028  80 PLSSTATVTITVL 92
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 67-144 6.54e-14

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 67.37  E-value: 6.54e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 57222296     67 SDLDNGNNS-FQYKLL-GTGDGSFSIDEKTGDIFAMQKLDREKQSLYILRAQVIDTTiGKAVEPESEFVIRVSDVNDNEP 144
Cdd:smart00112   3 TDADSGENGkVTYSILsGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGG-GPPLSSTATVTITVLDVNDNAP 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 391-466 2.39e-13

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 65.83  E-value: 2.39e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 57222296    391 SAVDPDRRQ-SPMRYSLIGS---KMFDIN-GNGTIVTTNLLDREVSAWYNLSVTATETYNVQQISSAHVYVQVLNINDHA 465
Cdd:smart00112   1 SATDADSGEnGKVTYSILSGnddGLFSIDpETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVNDNA 80


                   .
gi 57222296    466 P 466
Cdd:smart00112  81 P 81
Cadherin pfam00028
Cadherin domain;
259-360 5.63e-11

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 59.62  E-value: 5.63e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 57222296   259 YRFTISESAPSGTTIGKIMAYDDDIGENAEMDYSI-EDDESQIFDIvidnETQEGIVILKKKVDFEHQNHYGIRVKVKNC 337
Cdd:pfam00028   1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYSIlGGGPGGNFRI----DPDTGDISTTKPLDRESIGEYELTVEATDS 76

                          90       100
                  ....*....|....*....|...
gi 57222296   338 hvdeelaPAHVNASTTYIKVQVE 360
Cdd:pfam00028  77 -------GGPPLSSTATVTITVL 92
Cadherin pfam00028
Cadherin domain;
49-119 6.21e-11

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 59.24  E-value: 6.21e-11
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 57222296    49 QFVVPEEMDTIQHVGRLR-SDLDNGNNS-FQYKLLGTG-DGSFSIDEKTGDIFAMQKLDREKQSLYILRAQVID 119
Cdd:pfam00028   2 SASVPENAPVGTEVLTVTaTDPDLGPNGrIFYSILGGGpGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATD 75
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 472-570 1.72e-10

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 58.48  E-value: 1.72e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 57222296 472 YETYVCENAESGEIIQTISAIDRDESIEDHHFYfnHSVEDTNNSSFILtdnQDNTAVILSNRagfSL-KEETVFYMIILI 550
Cdd:cd11304   2 YEVSVPENAPPGTVVLTVSATDPDSGENGEVTY--SIVSGNEDGLFSI---DPSTGEITTAK---PLdREEQSSYTLTVT 73

                        90       100
                ....*....|....*....|.
gi 57222296 551 A-DNGIPPLTSTNTLTIQVCD 570
Cdd:cd11304  74 AtDGGGPPLSSTATVTITVLD 94
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 278-366 7.06e-08

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 50.43  E-value: 7.06e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 57222296    278 AYDDDIGENAEMDYSIED-DESQIFDIviDNETqeGIVILKKKVDFEHQNHYGIRVKVKNCHVdeelapaHVNASTTYIK 356
Cdd:smart00112   2 ATDADSGENGKVTYSILSgNDDGLFSI--DPET--GEITTTKPLDREEQPEYTLTVEATDGGG-------PPLSSTATVT 70

                           90
                   ....*....|.
gi 57222296    357 VQVEDE-DEPP 366
Cdd:smart00112  71 ITVLDVnDNAP 81
Cadherin pfam00028
Cadherin domain;
472-569 2.02e-06

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 46.52  E-value: 2.02e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 57222296   472 YETYVCENAESGEIIQTISAIDRDEsiEDHH--FYF--NHSVEDtnnsSFIL-TDNQD-NTAVILSnragfslKEETVFY 545
Cdd:pfam00028   1 YSASVPENAPVGTEVLTVTATDPDL--GPNGriFYSilGGGPGG----NFRIdPDTGDiSTTKPLD-------RESIGEY 67

                          90       100
                  ....*....|....*....|....*
gi 57222296   546 MIILIA-DNGIPPLTSTNTLTIQVC 569
Cdd:pfam00028  68 ELTVEAtDSGGPPLSSTATVTITVL 92
 
Name Accession Description Interval E-value
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 150-250 6.76e-27

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 105.09  E-value: 6.76e-27
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 57222296 150 PYEAIVPEMSPEGTFVIKVTANDADdptSGYHARILYNLEQGQP--YFSVEPTTGVIRISSKMDRELQDTYCVIIQAKDM 227
Cdd:cd11304   1 SYEVSVPENAPPGTVVLTVSATDPD---SGENGEVTYSIVSGNEdgLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDG 77

                        90       100
                ....*....|....*....|...
gi 57222296 228 LGQPgaLSGTTTISIKLSDINDN 250
Cdd:cd11304  78 GGPP--LSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 373-464 8.91e-23

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 93.15  E-value: 8.91e-23
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 57222296 373 YIFEIPEGKPYGTMVGTVSAVDPDR-RQSPMRYSLIG---SKMFDINGN-GTIVTTNLLDREVSAWYNLSVTATETYNVQ 447
Cdd:cd11304   2 YEVSVPENAPPGTVVLTVSATDPDSgENGEVTYSIVSgneDGLFSIDPStGEITTAKPLDREEQSSYTLTVTATDGGGPP 81

                        90
                ....*....|....*..
gi 57222296 448 QISSAHVYVQVLNINDH 464
Cdd:cd11304  82 LSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 259-364 4.47e-18

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 80.05  E-value: 4.47e-18
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 57222296 259 YRFTISESAPSGTTIGKIMAYDDDIGENAEMDYSI-EDDESQIFDIvidnETQEGIVILKKKVDFEHQNHYGIRVKVKNC 337
Cdd:cd11304   2 YEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIvSGNEDGLFSI----DPSTGEITTAKPLDREEQSSYTLTVTATDG 77

                        90       100
                ....*....|....*....|....*..
gi 57222296 338 HVdeelapaHVNASTTYIKVQVEDEDE 364
Cdd:cd11304  78 GG-------PPLSSTATVTITVLDVND 97
CADH_Y-type_LIR pfam01049
Cadherin, Y-type LIR-motif; LC3 Interacting Regions (LIRs), also known as ATG8-interacting ...
 704-763 7.43e-18

Cadherin, Y-type LIR-motif; LC3 Interacting Regions (LIRs), also known as ATG8-interacting motifs (AIMs), are short-linear motifs (SLiMs) of autophagy receptors and adaptor proteins that facilitates the selective recruitment of autophagy substrates to the autophagosome. LIRs are characterized by degenerated sequences with a four-residue core central sequence involved in ATG8-binding, with the W/Y/FxxL/I/V pattern. Based on the aromatic amino acid in position 1 they can be classified into W-type, Y-type and F-type. This entry includes three conserved LIR motifs of CADHs, which two are Y-type (YDxL/I) and one F-type (FKKL), while a fourth LIR (YGGV) is only present in CADH6 members. Cadherins (CADH) have a crucial role in epithelial-to-mesenchymal transition (EMT), involved in migration properties of tumour cells. CADH6 is an EMT marker in thyroid cancer that interacts with the ATG8 family members GABARAP, BNIP3 and BNIP3L restraining autophagy through LIR domains, a common feature among many cadherin family members.


Pssm-ID: 460041  Cd Length: 60  Bit Score: 77.96  E-value: 7.43e-18
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 57222296   704 ANTDSSAPPFDSLQTFAYEGTGSSAGSLSSLGSSVTDQEDDFDYLNDLGPCFKRLANMFG 763
Cdd:pfam01049   1 ADNDPSAPPYDSLQTYAYEGDGSSAGSLSSLESSTSDSDQDYDYLSDWGPRFKKLAELYG 60
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 49-142 2.00e-17

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 78.12  E-value: 2.00e-17
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 57222296  49 QFVVPEEMDTIQHVGRLR-SDLDNGNNS-FQYKLL-GTGDGSFSIDEKTGDIFAMQKLDREKQSLYILRAQVIDTTiGKA 125
Cdd:cd11304   3 EVSVPENAPPGTVVLTVSaTDPDSGENGeVTYSIVsGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGG-GPP 81

                        90
                ....*....|....*..
gi 57222296 126 VEPESEFVIRVSDVNDN 142
Cdd:cd11304  82 LSSTATVTITVLDVNDN 98
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 169-252 3.67e-17

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 76.62  E-value: 3.67e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 57222296    169 TANDADDPTSGyhaRILYNLEQG--QPYFSVEPTTGVIRISSKMDRELQDTYCVIIQAKDMLGQPgaLSGTTTISIKLSD 246
Cdd:smart00112   1 SATDADSGENG---KVTYSILSGndDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPP--LSSTATVTITVLD 75


                   ....*.
gi 57222296    247 INDNKP 252
Cdd:smart00112  76 VNDNAP 81
Cadherin pfam00028
Cadherin domain;
151-244 2.65e-16

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 74.64  E-value: 2.65e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 57222296   151 YEAIVPEMSPEGTFVIKVTANDADDPTsgyHARILYNLEQGQPY--FSVEPTTGVIRISSKMDRELQDTYCVIIQAKDML 228
Cdd:pfam00028   1 YSASVPENAPVGTEVLTVTATDPDLGP---NGRIFYSILGGGPGgnFRIDPDTGDISTTKPLDRESIGEYELTVEATDSG 77

                          90
                  ....*....|....*.
gi 57222296   229 GQPgaLSGTTTISIKL 244
Cdd:pfam00028  78 GPP--LSSTATVTITV 91
Cadherin pfam00028
Cadherin domain;
373-459 2.61e-15

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 71.95  E-value: 2.61e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 57222296   373 YIFEIPEGKPYGTMVGTVSAVDPDR--RQSPmRYSLIG---SKMFDIN-GNGTIVTTNLLDREVSAWYNLSVTATETYNV 446
Cdd:pfam00028   1 YSASVPENAPVGTEVLTVTATDPDLgpNGRI-FYSILGggpGGNFRIDpDTGDISTTKPLDRESIGEYELTVEATDSGGP 79

                          90
                  ....*....|...
gi 57222296   447 QQISSAHVYVQVL 459
Cdd:pfam00028  80 PLSSTATVTITVL 92
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 67-144 6.54e-14

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 67.37  E-value: 6.54e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 57222296     67 SDLDNGNNS-FQYKLL-GTGDGSFSIDEKTGDIFAMQKLDREKQSLYILRAQVIDTTiGKAVEPESEFVIRVSDVNDNEP 144
Cdd:smart00112   3 TDADSGENGkVTYSILsGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGG-GPPLSSTATVTITVLDVNDNAP 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 391-466 2.39e-13

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 65.83  E-value: 2.39e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 57222296    391 SAVDPDRRQ-SPMRYSLIGS---KMFDIN-GNGTIVTTNLLDREVSAWYNLSVTATETYNVQQISSAHVYVQVLNINDHA 465
Cdd:smart00112   1 SATDADSGEnGKVTYSILSGnddGLFSIDpETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVNDNA 80


                   .
gi 57222296    466 P 466
Cdd:smart00112  81 P 81
Cadherin pfam00028
Cadherin domain;
259-360 5.63e-11

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 59.62  E-value: 5.63e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 57222296   259 YRFTISESAPSGTTIGKIMAYDDDIGENAEMDYSI-EDDESQIFDIvidnETQEGIVILKKKVDFEHQNHYGIRVKVKNC 337
Cdd:pfam00028   1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYSIlGGGPGGNFRI----DPDTGDISTTKPLDRESIGEYELTVEATDS 76

                          90       100
                  ....*....|....*....|...
gi 57222296   338 hvdeelaPAHVNASTTYIKVQVE 360
Cdd:pfam00028  77 -------GGPPLSSTATVTITVL 92
Cadherin pfam00028
Cadherin domain;
49-119 6.21e-11

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 59.24  E-value: 6.21e-11
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 57222296    49 QFVVPEEMDTIQHVGRLR-SDLDNGNNS-FQYKLLGTG-DGSFSIDEKTGDIFAMQKLDREKQSLYILRAQVID 119
Cdd:pfam00028   2 SASVPENAPVGTEVLTVTaTDPDLGPNGrIFYSILGGGpGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATD 75
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 472-570 1.72e-10

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 58.48  E-value: 1.72e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 57222296 472 YETYVCENAESGEIIQTISAIDRDESIEDHHFYfnHSVEDTNNSSFILtdnQDNTAVILSNRagfSL-KEETVFYMIILI 550
Cdd:cd11304   2 YEVSVPENAPPGTVVLTVSATDPDSGENGEVTY--SIVSGNEDGLFSI---DPSTGEITTAK---PLdREEQSSYTLTVT 73

                        90       100
                ....*....|....*....|.
gi 57222296 551 A-DNGIPPLTSTNTLTIQVCD 570
Cdd:cd11304  74 AtDGGGPPLSSTATVTITVLD 94
CA_like cd00031
Cadherin repeat-like domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 52-142 3.32e-08

Cadherin repeat-like domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers. This family also includes the cadherin-like repeats of extracellular alpha-dystroglycan.


Pssm-ID: 206635  Cd Length: 98  Bit Score: 51.96  E-value: 3.32e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 57222296  52 VPEEMDTIQHVGRLRSDLDNGNNSFqYKLLGTGD----GSFSIDEKTGDIFAMQKLDREKQSLYILRAQVIDTTiGKAVE 127
Cdd:cd00031   6 AVEGRSRGSFRVSIPTDLIASSGEI-IKISAAGKealpSWLHWEPHSGILEGLEKLDREDKGVHYISVSAASLG-ANVPQ 83

                        90
                ....*....|....*
gi 57222296 128 PESEFVIRVSDVNDN 142
Cdd:cd00031  84 TSSVFSIEVYDENDN 98
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 278-366 7.06e-08

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 50.43  E-value: 7.06e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 57222296    278 AYDDDIGENAEMDYSIED-DESQIFDIviDNETqeGIVILKKKVDFEHQNHYGIRVKVKNCHVdeelapaHVNASTTYIK 356
Cdd:smart00112   2 ATDADSGENGKVTYSILSgNDDGLFSI--DPET--GEITTTKPLDREEQPEYTLTVEATDGGG-------PPLSSTATVT 70

                           90
                   ....*....|.
gi 57222296    357 VQVEDE-DEPP 366
Cdd:smart00112  71 ITVLDVnDNAP 81
Cadherin pfam00028
Cadherin domain;
472-569 2.02e-06

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 46.52  E-value: 2.02e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 57222296   472 YETYVCENAESGEIIQTISAIDRDEsiEDHH--FYF--NHSVEDtnnsSFIL-TDNQD-NTAVILSnragfslKEETVFY 545
Cdd:pfam00028   1 YSASVPENAPVGTEVLTVTATDPDL--GPNGriFYSilGGGPGG----NFRIdPDTGDiSTTKPLD-------RESIGEY 67

                          90       100
                  ....*....|....*....|....*
gi 57222296   546 MIILIA-DNGIPPLTSTNTLTIQVC 569
Cdd:pfam00028  68 ELTVEAtDSGGPPLSSTATVTITVL 92
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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