olfactomedin 1b isoform 3 precursor [Danio rerio]
List of domain hits
Name | Accession | Description | Interval | E-value | |||
Noelin-1 super family | cl13708 | Neurogenesis glycoprotein; This domain family is found in eukaryotes, and is approximately 100 ... |
28-124 | 4.86e-47 | |||
Neurogenesis glycoprotein; This domain family is found in eukaryotes, and is approximately 100 amino acids in length. The family is found in association with pfam02191. There are two conserved sequence motifs: SAQ and VQN. Noelin-1 is a glycoprotein which is secreted mainly by postmitotic neurogenic tissues in the developing central and peripheral nervous systems, first appearing after neural tube closure. It is likely that it forms large multimeric complexes.It has a divergent function in neurogenesis. In animal caps neuralized by expression of noggin, co-expression of Noelin-1 causes expression of neuronal differentiation markers several stages before neurogenesis normally occurs in this tissue. Finally, only secreted forms of the protein can activate sensory marker expression, while all forms of the protein can induce early neurogenesis. The actual alignment was detected with superfamily member pfam12308: Pssm-ID: 432468 [Multi-domain] Cd Length: 100 Bit Score: 146.85 E-value: 4.86e-47
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Name | Accession | Description | Interval | E-value | |||
Noelin-1 | pfam12308 | Neurogenesis glycoprotein; This domain family is found in eukaryotes, and is approximately 100 ... |
28-124 | 4.86e-47 | |||
Neurogenesis glycoprotein; This domain family is found in eukaryotes, and is approximately 100 amino acids in length. The family is found in association with pfam02191. There are two conserved sequence motifs: SAQ and VQN. Noelin-1 is a glycoprotein which is secreted mainly by postmitotic neurogenic tissues in the developing central and peripheral nervous systems, first appearing after neural tube closure. It is likely that it forms large multimeric complexes.It has a divergent function in neurogenesis. In animal caps neuralized by expression of noggin, co-expression of Noelin-1 causes expression of neuronal differentiation markers several stages before neurogenesis normally occurs in this tissue. Finally, only secreted forms of the protein can activate sensory marker expression, while all forms of the protein can induce early neurogenesis. Pssm-ID: 432468 [Multi-domain] Cd Length: 100 Bit Score: 146.85 E-value: 4.86e-47
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Name | Accession | Description | Interval | E-value | |||
Noelin-1 | pfam12308 | Neurogenesis glycoprotein; This domain family is found in eukaryotes, and is approximately 100 ... |
28-124 | 4.86e-47 | |||
Neurogenesis glycoprotein; This domain family is found in eukaryotes, and is approximately 100 amino acids in length. The family is found in association with pfam02191. There are two conserved sequence motifs: SAQ and VQN. Noelin-1 is a glycoprotein which is secreted mainly by postmitotic neurogenic tissues in the developing central and peripheral nervous systems, first appearing after neural tube closure. It is likely that it forms large multimeric complexes.It has a divergent function in neurogenesis. In animal caps neuralized by expression of noggin, co-expression of Noelin-1 causes expression of neuronal differentiation markers several stages before neurogenesis normally occurs in this tissue. Finally, only secreted forms of the protein can activate sensory marker expression, while all forms of the protein can induce early neurogenesis. Pssm-ID: 432468 [Multi-domain] Cd Length: 100 Bit Score: 146.85 E-value: 4.86e-47
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Blast search parameters | ||||
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