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Conserved domains on  [gi|282721063|ref|NP_001002912|]
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glutamate-rich protein 3 [Homo sapiens]

Protein Classification

UBX domain-containing protein; FRMD7 family protein( domain architecture ID 13866763)

UBX domain-containing protein similar to Schizosaccharomyces pombe protein C17C9.11c| FRMD7 family protein similar to Homo sapiens FERM domain-containing protein 7 (FRMD7) that plays a role in neurite development, and N-terminal region of Homo sapiens FERM, ARHGEF and pleckstrin domain-containing protein 1/2 that functions as guanine nucleotide exchange factor for RAC1

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
DUF4590 pfam15257
Domain of unknown function (DUF4590); This family of proteins remains to be characterized and ...
299-411 5.70e-73

Domain of unknown function (DUF4590); This family of proteins remains to be characterized and is a domain of unknown function. This domain family is found in eukaryotes, and is approximately 120 amino acids in length. There are two conserved sequence motifs: CCE and PCY. In humans, the gene encoding this protein lies in the position, chromosome 1 open reading frame 173.


:

Pssm-ID: 464597  Cd Length: 114  Bit Score: 238.04  E-value: 5.70e-73
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 282721063   299 HLSSDNPDFRDEIKVYQQHCGGENLCVYKGKLLEKETFQFISKRHHGFPFSLTFFLNGMQVNRLSSCCEYKHRKGSRLGG 378
Cdd:pfam15257    1 HLSHDQFDYRDEIKVYQQHCGGENLCVFKGKLLEGETFQFISRRHRGFPFSLTFYLNGLQVDRLSSCCEYKHRKGSRLGG 80
                           90       100       110
                   ....*....|....*....|....*....|...
gi 282721063   379 KRGYFGFVCVERSSPCYKCIIAMGLDKKPSLPK 411
Cdd:pfam15257   81 KSGHFGFLSVEGASPCYKCIIAMGLDKKPSPPP 113
PTZ00121 super family cl31754
MAEBL; Provisional
413-1121 1.47e-06

MAEBL; Provisional


The actual alignment was detected with superfamily member PTZ00121:

Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 53.22  E-value: 1.47e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 282721063  413 RKEKSTEKGEELKKAEGKVRKEREYVIPKRNEIKENKTSVSAKfSAQEIKTGLKEVVTAVEEMTSKG--KPGQEVLEDDQ 490
Cdd:PTZ00121 1188 RKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVK-KAEEAKKDAEEAKKAEEERNNEEirKFEEARMAHFA 1266
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 282721063  491 ENTLKYEYEEDFEVDEEKQGEksnEEGQADVQMNGIPQSPLDDKKDNLDPEKESETSSQKAPDARDNVKDendgcSESEL 570
Cdd:PTZ00121 1267 RRQAAIKAEEARKADELKKAE---EKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADA-----AKKKA 1338
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 282721063  571 EEDKQDMKTASSTSSRSHPYSSDSEDESAVGDREAHTDSSTDESARRSSSQELSENDKPRKSHLPIEESLEIEIEDQEIT 650
Cdd:PTZ00121 1339 EEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKK 1418
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 282721063  651 KADVETKPMPIDESFENVLKEGTEKGTQEIAEGLSEKSGKHVSAEEKEKDKSKLWEESTAQVKDKKAglpglEEGGKDsl 730
Cdd:PTZ00121 1419 KADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKA-----DEAKKK-- 1491
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 282721063  731 playvlalgaptmnfmvdetaAINSNKESQQLVQKTYtlEKKEAMEEDEAPQHRDADIVQGKGEAALWGEAGAVHEaplr 810
Cdd:PTZ00121 1492 ---------------------AEEAKKKADEAKKAAE--AKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEE---- 1544
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 282721063  811 awKPTAEQPELAEEFTEKREIPPGIERGAEGAAEAEGVRRLGEggsdpigqaaakdavgLSKDEAPEKQALMLTVLETDK 890
Cdd:PTZ00121 1545 --KKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEE----------------AKKAEEARIEEVMKLYEEEKK 1606
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 282721063  891 AASEGEQGLEKAVLANEAAALNLEHLHEVAALREAATSEEGEAEggvavsDVGESEEEASIDledtgpMEDTASKREDGS 970
Cdd:PTZ00121 1607 MKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAE------ELKKAEEENKIK------AAEEAKKAEEDK 1674
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 282721063  971 EEAilggEEPAKERKEVMRTEtrlspftgeaEASRMQVSEGSPEEGSLAKEAflckEDVEGEEMVTEAEANREDDRKEIl 1050
Cdd:PTZ00121 1675 KKA----EEAKKAEEDEKKAA----------EALKKEAEEAKKAEELKKKEA----EEKKKAEELKKAEEENKIKAEEA- 1735
                         650       660       670       680       690       700       710
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 282721063 1051 pkeldlareRRKAERPKTSLRKTDSEREEVTRANALKDEDAFKEEQKLKAEEGETETEVRAEEETKAPPNE 1121
Cdd:PTZ00121 1736 ---------KKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVD 1797
PTZ00121 super family cl31754
MAEBL; Provisional
971-1414 1.07e-04

MAEBL; Provisional


The actual alignment was detected with superfamily member PTZ00121:

Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 47.06  E-value: 1.07e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 282721063  971 EEAILGGEEPAKERKEVMRTETRLSPFTGEAEASRMQVSEGSpEEGSLAKEAFLCKEDVEGEEMVTEAEANREDDRKEIL 1050
Cdd:PTZ00121 1233 EEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKA-EEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKA 1311
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 282721063 1051 PKELDLARERRKAERPKTSLRKTDSEREEVTRANALKDEDAFKEEQKLKAEEGETETEVRAEEETKAPPNEMGSDAENEA 1130
Cdd:PTZ00121 1312 EEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKK 1391
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 282721063 1131 PVEASELSDNPGLLGEDSLKETVVPIFEATPGFEKSLENITALRKEGGGERLSEARDTEHKDREELSSRENRALKEGHRQ 1210
Cdd:PTZ00121 1392 KADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKK 1471
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 282721063 1211 DGEGAL--AAPEAEPAGKVQAPEglipATGQAEELAAKDHDSCAGLEGR-AEGQGGVDVVLRTQEAVAEEDPIMAEKFRE 1287
Cdd:PTZ00121 1472 ADEAKKkaEEAKKADEAKKKAEE----AKKKADEAKKAAEAKKKADEAKkAEEAKKADEAKKAEEAKKADEAKKAEEKKK 1547
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 282721063 1288 EAVDEDPEEEEDKECTLETEAMQDRNSEGDGDMEGEGNTQKNEGMGGGRVVAVEVLHGGGETAETAAEEREVLAGSETAE 1367
Cdd:PTZ00121 1548 ADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKK 1627
                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*..
gi 282721063 1368 EKTIANKASSFSDVAEEETwhQQDELVGKTAAAGKVVVEELARSGEE 1414
Cdd:PTZ00121 1628 AEEEKKKVEQLKKKEAEEK--KKAEELKKAEEENKIKAAEEAKKAEE 1672
 
Name Accession Description Interval E-value
DUF4590 pfam15257
Domain of unknown function (DUF4590); This family of proteins remains to be characterized and ...
299-411 5.70e-73

Domain of unknown function (DUF4590); This family of proteins remains to be characterized and is a domain of unknown function. This domain family is found in eukaryotes, and is approximately 120 amino acids in length. There are two conserved sequence motifs: CCE and PCY. In humans, the gene encoding this protein lies in the position, chromosome 1 open reading frame 173.


Pssm-ID: 464597  Cd Length: 114  Bit Score: 238.04  E-value: 5.70e-73
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 282721063   299 HLSSDNPDFRDEIKVYQQHCGGENLCVYKGKLLEKETFQFISKRHHGFPFSLTFFLNGMQVNRLSSCCEYKHRKGSRLGG 378
Cdd:pfam15257    1 HLSHDQFDYRDEIKVYQQHCGGENLCVFKGKLLEGETFQFISRRHRGFPFSLTFYLNGLQVDRLSSCCEYKHRKGSRLGG 80
                           90       100       110
                   ....*....|....*....|....*....|...
gi 282721063   379 KRGYFGFVCVERSSPCYKCIIAMGLDKKPSLPK 411
Cdd:pfam15257   81 KSGHFGFLSVEGASPCYKCIIAMGLDKKPSPPP 113
PTZ00121 PTZ00121
MAEBL; Provisional
413-1121 1.47e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 53.22  E-value: 1.47e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 282721063  413 RKEKSTEKGEELKKAEGKVRKEREYVIPKRNEIKENKTSVSAKfSAQEIKTGLKEVVTAVEEMTSKG--KPGQEVLEDDQ 490
Cdd:PTZ00121 1188 RKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVK-KAEEAKKDAEEAKKAEEERNNEEirKFEEARMAHFA 1266
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 282721063  491 ENTLKYEYEEDFEVDEEKQGEksnEEGQADVQMNGIPQSPLDDKKDNLDPEKESETSSQKAPDARDNVKDendgcSESEL 570
Cdd:PTZ00121 1267 RRQAAIKAEEARKADELKKAE---EKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADA-----AKKKA 1338
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 282721063  571 EEDKQDMKTASSTSSRSHPYSSDSEDESAVGDREAHTDSSTDESARRSSSQELSENDKPRKSHLPIEESLEIEIEDQEIT 650
Cdd:PTZ00121 1339 EEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKK 1418
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 282721063  651 KADVETKPMPIDESFENVLKEGTEKGTQEIAEGLSEKSGKHVSAEEKEKDKSKLWEESTAQVKDKKAglpglEEGGKDsl 730
Cdd:PTZ00121 1419 KADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKA-----DEAKKK-- 1491
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 282721063  731 playvlalgaptmnfmvdetaAINSNKESQQLVQKTYtlEKKEAMEEDEAPQHRDADIVQGKGEAALWGEAGAVHEaplr 810
Cdd:PTZ00121 1492 ---------------------AEEAKKKADEAKKAAE--AKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEE---- 1544
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 282721063  811 awKPTAEQPELAEEFTEKREIPPGIERGAEGAAEAEGVRRLGEggsdpigqaaakdavgLSKDEAPEKQALMLTVLETDK 890
Cdd:PTZ00121 1545 --KKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEE----------------AKKAEEARIEEVMKLYEEEKK 1606
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 282721063  891 AASEGEQGLEKAVLANEAAALNLEHLHEVAALREAATSEEGEAEggvavsDVGESEEEASIDledtgpMEDTASKREDGS 970
Cdd:PTZ00121 1607 MKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAE------ELKKAEEENKIK------AAEEAKKAEEDK 1674
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 282721063  971 EEAilggEEPAKERKEVMRTEtrlspftgeaEASRMQVSEGSPEEGSLAKEAflckEDVEGEEMVTEAEANREDDRKEIl 1050
Cdd:PTZ00121 1675 KKA----EEAKKAEEDEKKAA----------EALKKEAEEAKKAEELKKKEA----EEKKKAEELKKAEEENKIKAEEA- 1735
                         650       660       670       680       690       700       710
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 282721063 1051 pkeldlareRRKAERPKTSLRKTDSEREEVTRANALKDEDAFKEEQKLKAEEGETETEVRAEEETKAPPNE 1121
Cdd:PTZ00121 1736 ---------KKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVD 1797
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
908-1213 4.49e-05

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 48.45  E-value: 4.49e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 282721063   908 AAALNLEHLHEVAALREAATSEEGEAEGGVAVSDVGESEEEASIDLEDTGPMEDTASKREDGSEEAILGGEEPAKERKEV 987
Cdd:TIGR00927  622 AKVMALGDLSKGDVAEAEHTGERTGEEGERPTEAEGENGEESGGEAEQEGETETKGENESEGEIPAERKGEQEGEGEIEA 701
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 282721063   988 MRTETRLSPFTGEAEASRMQVSEGSPEEGSLAKEAflcKEDVEGEEMVTEAEANREDDrkeilpkeldlarerRKAERPK 1067
Cdd:TIGR00927  702 KEADHKGETEAEEVEHEGETEAEGTEDEGEIETGE---EGEEVEDEGEGEAEGKHEVE---------------TEGDRKE 763
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 282721063  1068 TslrktdsEREEVTRANALKDEDafkeEQKLKAEEGETETEVRAEEETKAPPNEMGSDAENEAPVEASELSDNPGLLGED 1147
Cdd:TIGR00927  764 T-------EHEGETEAEGKEDED----EGEIQAGEDGEMKGDEGAEGKVEHEGETEAGEKDEHEGQSETQADDTEVKDET 832
                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 282721063  1148 SLKETVVPIFEATPGFEKSLENitalrkeGGGERLSEARDTEHKDREELSSRENRALKEGHRQDGE 1213
Cdd:TIGR00927  833 GEQELNAENQGEAKQDEKGVDG-------GGGSDGGDSEEEEEEEEEEEEEEEEEEEEEEEEEENE 891
PTZ00121 PTZ00121
MAEBL; Provisional
971-1414 1.07e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 47.06  E-value: 1.07e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 282721063  971 EEAILGGEEPAKERKEVMRTETRLSPFTGEAEASRMQVSEGSpEEGSLAKEAFLCKEDVEGEEMVTEAEANREDDRKEIL 1050
Cdd:PTZ00121 1233 EEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKA-EEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKA 1311
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 282721063 1051 PKELDLARERRKAERPKTSLRKTDSEREEVTRANALKDEDAFKEEQKLKAEEGETETEVRAEEETKAPPNEMGSDAENEA 1130
Cdd:PTZ00121 1312 EEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKK 1391
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 282721063 1131 PVEASELSDNPGLLGEDSLKETVVPIFEATPGFEKSLENITALRKEGGGERLSEARDTEHKDREELSSRENRALKEGHRQ 1210
Cdd:PTZ00121 1392 KADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKK 1471
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 282721063 1211 DGEGAL--AAPEAEPAGKVQAPEglipATGQAEELAAKDHDSCAGLEGR-AEGQGGVDVVLRTQEAVAEEDPIMAEKFRE 1287
Cdd:PTZ00121 1472 ADEAKKkaEEAKKADEAKKKAEE----AKKKADEAKKAAEAKKKADEAKkAEEAKKADEAKKAEEAKKADEAKKAEEKKK 1547
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 282721063 1288 EAVDEDPEEEEDKECTLETEAMQDRNSEGDGDMEGEGNTQKNEGMGGGRVVAVEVLHGGGETAETAAEEREVLAGSETAE 1367
Cdd:PTZ00121 1548 ADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKK 1627
                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*..
gi 282721063 1368 EKTIANKASSFSDVAEEETwhQQDELVGKTAAAGKVVVEELARSGEE 1414
Cdd:PTZ00121 1628 AEEEKKKVEQLKKKEAEEK--KKAEELKKAEEENKIKAAEEAKKAEE 1672
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
1305-1510 1.65e-04

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 46.53  E-value: 1.65e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 282721063  1305 ETEAMQDRNSEGDGDMEGEGNTQKNEGMGGGRVVAVEVLHGGGETAETAAEEREVLAGSETAE----------------- 1367
Cdd:TIGR00927  678 ENESEGEIPAERKGEQEGEGEIEAKEADHKGETEAEEVEHEGETEAEGTEDEGEIETGEEGEEvedegegeaegkhevet 757
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 282721063  1368 -------EKTIANKASSFSDVAEEETWHQQD-ELVGKTAAAGKVVVEELARSGEEVPAAEEMTVTYTTEAGVGTPGalER 1439
Cdd:TIGR00927  758 egdrketEHEGETEAEGKEDEDEGEIQAGEDgEMKGDEGAEGKVEHEGETEAGEKDEHEGQSETQADDTEVKDETG--EQ 835
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 282721063  1440 KTSGLGQEQEEGSEGQEAATGSGDGrQETGAAEKFRLGLSREGERELSPESLQAMATLPVKPDFTETREKQ 1510
Cdd:TIGR00927  836 ELNAENQGEAKQDEKGVDGGGGSDG-GDSEEEEEEEEEEEEEEEEEEEEEEEEEENEEPLSLEWPETRQKQ 905
 
Name Accession Description Interval E-value
DUF4590 pfam15257
Domain of unknown function (DUF4590); This family of proteins remains to be characterized and ...
299-411 5.70e-73

Domain of unknown function (DUF4590); This family of proteins remains to be characterized and is a domain of unknown function. This domain family is found in eukaryotes, and is approximately 120 amino acids in length. There are two conserved sequence motifs: CCE and PCY. In humans, the gene encoding this protein lies in the position, chromosome 1 open reading frame 173.


Pssm-ID: 464597  Cd Length: 114  Bit Score: 238.04  E-value: 5.70e-73
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 282721063   299 HLSSDNPDFRDEIKVYQQHCGGENLCVYKGKLLEKETFQFISKRHHGFPFSLTFFLNGMQVNRLSSCCEYKHRKGSRLGG 378
Cdd:pfam15257    1 HLSHDQFDYRDEIKVYQQHCGGENLCVFKGKLLEGETFQFISRRHRGFPFSLTFYLNGLQVDRLSSCCEYKHRKGSRLGG 80
                           90       100       110
                   ....*....|....*....|....*....|...
gi 282721063   379 KRGYFGFVCVERSSPCYKCIIAMGLDKKPSLPK 411
Cdd:pfam15257   81 KSGHFGFLSVEGASPCYKCIIAMGLDKKPSPPP 113
PTZ00121 PTZ00121
MAEBL; Provisional
413-1121 1.47e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 53.22  E-value: 1.47e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 282721063  413 RKEKSTEKGEELKKAEGKVRKEREYVIPKRNEIKENKTSVSAKfSAQEIKTGLKEVVTAVEEMTSKG--KPGQEVLEDDQ 490
Cdd:PTZ00121 1188 RKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVK-KAEEAKKDAEEAKKAEEERNNEEirKFEEARMAHFA 1266
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 282721063  491 ENTLKYEYEEDFEVDEEKQGEksnEEGQADVQMNGIPQSPLDDKKDNLDPEKESETSSQKAPDARDNVKDendgcSESEL 570
Cdd:PTZ00121 1267 RRQAAIKAEEARKADELKKAE---EKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADA-----AKKKA 1338
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 282721063  571 EEDKQDMKTASSTSSRSHPYSSDSEDESAVGDREAHTDSSTDESARRSSSQELSENDKPRKSHLPIEESLEIEIEDQEIT 650
Cdd:PTZ00121 1339 EEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKK 1418
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 282721063  651 KADVETKPMPIDESFENVLKEGTEKGTQEIAEGLSEKSGKHVSAEEKEKDKSKLWEESTAQVKDKKAglpglEEGGKDsl 730
Cdd:PTZ00121 1419 KADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKA-----DEAKKK-- 1491
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 282721063  731 playvlalgaptmnfmvdetaAINSNKESQQLVQKTYtlEKKEAMEEDEAPQHRDADIVQGKGEAALWGEAGAVHEaplr 810
Cdd:PTZ00121 1492 ---------------------AEEAKKKADEAKKAAE--AKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEE---- 1544
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 282721063  811 awKPTAEQPELAEEFTEKREIPPGIERGAEGAAEAEGVRRLGEggsdpigqaaakdavgLSKDEAPEKQALMLTVLETDK 890
Cdd:PTZ00121 1545 --KKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEE----------------AKKAEEARIEEVMKLYEEEKK 1606
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 282721063  891 AASEGEQGLEKAVLANEAAALNLEHLHEVAALREAATSEEGEAEggvavsDVGESEEEASIDledtgpMEDTASKREDGS 970
Cdd:PTZ00121 1607 MKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAE------ELKKAEEENKIK------AAEEAKKAEEDK 1674
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 282721063  971 EEAilggEEPAKERKEVMRTEtrlspftgeaEASRMQVSEGSPEEGSLAKEAflckEDVEGEEMVTEAEANREDDRKEIl 1050
Cdd:PTZ00121 1675 KKA----EEAKKAEEDEKKAA----------EALKKEAEEAKKAEELKKKEA----EEKKKAEELKKAEEENKIKAEEA- 1735
                         650       660       670       680       690       700       710
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 282721063 1051 pkeldlareRRKAERPKTSLRKTDSEREEVTRANALKDEDAFKEEQKLKAEEGETETEVRAEEETKAPPNE 1121
Cdd:PTZ00121 1736 ---------KKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVD 1797
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
908-1213 4.49e-05

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 48.45  E-value: 4.49e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 282721063   908 AAALNLEHLHEVAALREAATSEEGEAEGGVAVSDVGESEEEASIDLEDTGPMEDTASKREDGSEEAILGGEEPAKERKEV 987
Cdd:TIGR00927  622 AKVMALGDLSKGDVAEAEHTGERTGEEGERPTEAEGENGEESGGEAEQEGETETKGENESEGEIPAERKGEQEGEGEIEA 701
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 282721063   988 MRTETRLSPFTGEAEASRMQVSEGSPEEGSLAKEAflcKEDVEGEEMVTEAEANREDDrkeilpkeldlarerRKAERPK 1067
Cdd:TIGR00927  702 KEADHKGETEAEEVEHEGETEAEGTEDEGEIETGE---EGEEVEDEGEGEAEGKHEVE---------------TEGDRKE 763
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 282721063  1068 TslrktdsEREEVTRANALKDEDafkeEQKLKAEEGETETEVRAEEETKAPPNEMGSDAENEAPVEASELSDNPGLLGED 1147
Cdd:TIGR00927  764 T-------EHEGETEAEGKEDED----EGEIQAGEDGEMKGDEGAEGKVEHEGETEAGEKDEHEGQSETQADDTEVKDET 832
                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 282721063  1148 SLKETVVPIFEATPGFEKSLENitalrkeGGGERLSEARDTEHKDREELSSRENRALKEGHRQDGE 1213
Cdd:TIGR00927  833 GEQELNAENQGEAKQDEKGVDG-------GGGSDGGDSEEEEEEEEEEEEEEEEEEEEEEEEEENE 891
PTZ00121 PTZ00121
MAEBL; Provisional
971-1414 1.07e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 47.06  E-value: 1.07e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 282721063  971 EEAILGGEEPAKERKEVMRTETRLSPFTGEAEASRMQVSEGSpEEGSLAKEAFLCKEDVEGEEMVTEAEANREDDRKEIL 1050
Cdd:PTZ00121 1233 EEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKA-EEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKA 1311
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 282721063 1051 PKELDLARERRKAERPKTSLRKTDSEREEVTRANALKDEDAFKEEQKLKAEEGETETEVRAEEETKAPPNEMGSDAENEA 1130
Cdd:PTZ00121 1312 EEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKK 1391
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 282721063 1131 PVEASELSDNPGLLGEDSLKETVVPIFEATPGFEKSLENITALRKEGGGERLSEARDTEHKDREELSSRENRALKEGHRQ 1210
Cdd:PTZ00121 1392 KADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKK 1471
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 282721063 1211 DGEGAL--AAPEAEPAGKVQAPEglipATGQAEELAAKDHDSCAGLEGR-AEGQGGVDVVLRTQEAVAEEDPIMAEKFRE 1287
Cdd:PTZ00121 1472 ADEAKKkaEEAKKADEAKKKAEE----AKKKADEAKKAAEAKKKADEAKkAEEAKKADEAKKAEEAKKADEAKKAEEKKK 1547
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 282721063 1288 EAVDEDPEEEEDKECTLETEAMQDRNSEGDGDMEGEGNTQKNEGMGGGRVVAVEVLHGGGETAETAAEEREVLAGSETAE 1367
Cdd:PTZ00121 1548 ADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKK 1627
                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*..
gi 282721063 1368 EKTIANKASSFSDVAEEETwhQQDELVGKTAAAGKVVVEELARSGEE 1414
Cdd:PTZ00121 1628 AEEEKKKVEQLKKKEAEEK--KKAEELKKAEEENKIKAAEEAKKAEE 1672
PTZ00121 PTZ00121
MAEBL; Provisional
555-1278 1.11e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 47.06  E-value: 1.11e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 282721063  555 RDNVKDENDGCSESELEEDKQDMKTASSTSSRSHPYSSDSEDESAVGDREAHTDSSTDESARRssSQELSENDKPRKSHl 634
Cdd:PTZ00121 1085 EDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARK--AEDAKRVEIARKAE- 1161
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 282721063  635 pIEESLEIEIEDQEITKADVETKPMPIDESFEnVLKEGTEKGTQEIAEGLSEKSGKHVSAEEKEKDKSKLWEESTAQVKD 714
Cdd:PTZ00121 1162 -DARKAEEARKAEDAKKAEAARKAEEVRKAEE-LRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDA 1239
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 282721063  715 KKAglpglEEGGKDSLPLAYVLALGAPTMNFMVDETAAINSNKESQQLVQKTYtlEKKEAMEEDEAPQHRDADIVQGKGE 794
Cdd:PTZ00121 1240 EEA-----KKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAE--EKKKADEAKKAEEKKKADEAKKKAE 1312
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 282721063  795 AALWGEAG--AVHEAPLRA--WKPTAEQPELAEEFTEKREIPPGIERGAEGAAEAEGVRRLGEGGSDpiGQAAAKDAVGL 870
Cdd:PTZ00121 1313 EAKKADEAkkKAEEAKKKAdaAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKK--ADAAKKKAEEK 1390
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 282721063  871 SKDEAPEKQAlmltvlETDKAASEGEQGLEKAVLANEAAALNLEHLHEVAALREAAtSEEGEAEGGVAVSDVGESEEEAS 950
Cdd:PTZ00121 1391 KKADEAKKKA------EEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKA-EEAKKADEAKKKAEEAKKAEEAK 1463
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 282721063  951 IDLEDTGPMEDTASKREDG--SEEAILGGEEPAKERKEVMRTETRlspfTGEAEASRMQVSEGSPEEGSLAKEAFLCKED 1028
Cdd:PTZ00121 1464 KKAEEAKKADEAKKKAEEAkkADEAKKKAEEAKKKADEAKKAAEA----KKKADEAKKAEEAKKADEAKKAEEAKKADEA 1539
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 282721063 1029 VEGEEMVTEAEANREDDRKEilPKELDLARERRKAERPKTSLRKTDSEREEVTRANALKDEDAFKEEQKLKAEEGETETE 1108
Cdd:PTZ00121 1540 KKAEEKKKADELKKAEELKK--AEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEE 1617
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 282721063 1109 VRAEEETKAPPNEMGSDAENEAPVEASELSDNPGLLGEDslKETVVPIFEATPGFEKSLENITALRKEGGGERLSEardt 1188
Cdd:PTZ00121 1618 AKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAE--EENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAA---- 1691
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 282721063 1189 EHKDREELSSRENRALKEGHRQDGEGALAAPEAEPAGKVQAPEGLIPA---TGQAEELAAKDHDSCAGLEGRAEGQGGVD 1265
Cdd:PTZ00121 1692 EALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAeedKKKAEEAKKDEEEKKKIAHLKKEEEKKAE 1771
                         730
                  ....*....|...
gi 282721063 1266 VVLRTQEAVAEED 1278
Cdd:PTZ00121 1772 EIRKEKEAVIEEE 1784
PTZ00341 PTZ00341
Ring-infected erythrocyte surface antigen; Provisional
414-699 1.14e-04

Ring-infected erythrocyte surface antigen; Provisional


Pssm-ID: 173534 [Multi-domain]  Cd Length: 1136  Bit Score: 47.09  E-value: 1.14e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 282721063  414 KEKSTEKGEELKKAEGKVRKereYVIPKRNEIKenktsvSAKFSAQEIKTGL-KEVVTAVEEMTSKGKPGQEVLEDDQEN 492
Cdd:PTZ00341  875 EKKLKKRAESLKKLANAIEK---YAGGGKKDKK------AKKKDAKDLSGNIaHEINLINKELKNQNENVPEHLKEHAEA 945
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 282721063  493 TLKYEYEEDFEVDEEKQGEKSNEEGqadvqmngIPQSPLDDKKDNLDPEKESETSSQKAPDARDNVKDENDGCSESELEE 572
Cdd:PTZ00341  946 NIEEDAEENVEEDAEENVEENVEEN--------VEENVEENVEENVEENVEENVEENVEENVEENIEENVEENVEENIEE 1017
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 282721063  573 DKQDMKTASSTSSRSHPYSSDSEDESAVgdreahtdsstDESARRSSSQELSENDKPRKSHLPIEESLEIEIEDQEITKA 652
Cdd:PTZ00341 1018 NVEEYDEENVEEVEENVEEYDEENVEEI-----------EENAEENVEENIEENIEEYDEENVEEIEENIEENIEENVEE 1086
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*..
gi 282721063  653 DVETKPMPIDESFENVLKEGTEKGTQEIAEGLSEKSGKHVSAEEKEK 699
Cdd:PTZ00341 1087 NVEENVEEIEENVEENVEENAEENAEENAEENAEEYDDENPEEHNEE 1133
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
1305-1510 1.65e-04

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 46.53  E-value: 1.65e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 282721063  1305 ETEAMQDRNSEGDGDMEGEGNTQKNEGMGGGRVVAVEVLHGGGETAETAAEEREVLAGSETAE----------------- 1367
Cdd:TIGR00927  678 ENESEGEIPAERKGEQEGEGEIEAKEADHKGETEAEEVEHEGETEAEGTEDEGEIETGEEGEEvedegegeaegkhevet 757
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 282721063  1368 -------EKTIANKASSFSDVAEEETWHQQD-ELVGKTAAAGKVVVEELARSGEEVPAAEEMTVTYTTEAGVGTPGalER 1439
Cdd:TIGR00927  758 egdrketEHEGETEAEGKEDEDEGEIQAGEDgEMKGDEGAEGKVEHEGETEAGEKDEHEGQSETQADDTEVKDETG--EQ 835
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 282721063  1440 KTSGLGQEQEEGSEGQEAATGSGDGrQETGAAEKFRLGLSREGERELSPESLQAMATLPVKPDFTETREKQ 1510
Cdd:TIGR00927  836 ELNAENQGEAKQDEKGVDGGGGSDG-GDSEEEEEEEEEEEEEEEEEEEEEEEEEENEEPLSLEWPETRQKQ 905
PTZ00121 PTZ00121
MAEBL; Provisional
406-1078 7.96e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 40.89  E-value: 7.96e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 282721063  406 KPSLPKSRKEKSTEKGEELKKAEgKVRKEREYVIPKRNEIKenKTSVSAKFSAQEIKTGLKEVVTAVEEMTSKGKPGQEV 485
Cdd:PTZ00121 1296 KKAEEKKKADEAKKKAEEAKKAD-EAKKKAEEAKKKADAAK--KKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKK 1372
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 282721063  486 LEDDQE--NTLKYEYEEDFEVDEEKQGEKSNEEGQADVQMNGIPQSPLDDKKDNLDPEKESETSSQKAPDAR--DNVKDE 561
Cdd:PTZ00121 1373 KEEAKKkaDAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKkaDEAKKK 1452
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 282721063  562 NDGCSESE-LEEDKQDMKTASSTSSRSHPYSSDSEDESAVGDREAHTDSSTDESARRSSSQELSENDKPRKShlpieesl 640
Cdd:PTZ00121 1453 AEEAKKAEeAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKA-------- 1524
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 282721063  641 eieiedQEITKADVETKPMPIDESfENVLKEGTEKGTQEIAEglseksgkhvsAEEKEKDKSKLWEESTAQVKDKKAG-L 719
Cdd:PTZ00121 1525 ------DEAKKAEEAKKADEAKKA-EEKKKADELKKAEELKK-----------AEEKKKAEEAKKAEEDKNMALRKAEeA 1586
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 282721063  720 PGLEEGGKDSLPLAYVLALGAPTMNFMVDETAAINSN--KESQQLVQKTYTLEKKEAMEEDEAPQHRDADivqgkgeaal 797
Cdd:PTZ00121 1587 KKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEelKKAEEEKKKVEQLKKKEAEEKKKAEELKKAE---------- 1656
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 282721063  798 wgEAGAVHEAPLRAW----KPTAEQPELAEEftEKREIPPGIERGAEGAAEAEGVRRLGEggsdpigqAAAKDAVGLSKD 873
Cdd:PTZ00121 1657 --EENKIKAAEEAKKaeedKKKAEEAKKAEE--DEKKAAEALKKEAEEAKKAEELKKKEA--------EEKKKAEELKKA 1724
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 282721063  874 EAPEKqalmltvLETDKAASEGEQGLEKAvlanEAAALNLEHLHEVAALREaatSEEGEAEGGVAVSDVGESEEEASIDL 953
Cdd:PTZ00121 1725 EEENK-------IKAEEAKKEAEEDKKKA----EEAKKDEEEKKKIAHLKK---EEEKKAEEIRKEKEAVIEEELDEEDE 1790
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 282721063  954 EDTGPMEDTASKREDGSEEAILGGEEPA---KERKEVMRTETRLSpftgeAEASRMQVsegspEEGSLAKEAFLCKEDVE 1030
Cdd:PTZ00121 1791 KRRMEVDKKIKDIFDNFANIIEGGKEGNlviNDSKEMEDSAIKEV-----ADSKNMQL-----EEADAFEKHKFNKNNEN 1860
                         650       660       670       680
                  ....*....|....*....|....*....|....*....|....*...
gi 282721063 1031 GEEMVTEAEANREDDRKEILPKELDLARERRKaerpktsLRKTDSERE 1078
Cdd:PTZ00121 1861 GEDGNKEADFNKEKDLKEDDEEEIEEADEIEK-------IDKDDIERE 1901
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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