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Conserved domains on  [gi|315113850|ref|NP_001002525|]
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ribonuclease P protein subunit p38 [Danio rerio]

Protein Classification

ribosomal L7Ae/L30e/S12e/Gadd45 family protein( domain architecture ID 10472466)

ribosomal L7Ae/L30e/S12e/Gadd45 family protein belongs to a family of K-turn-binding proteins that are important in ribosome structure, the site-specific modification of RNA, and spliceosome assembly

CATH:  3.30.1330.30
Gene Ontology:  GO:0003735|GO:0042274
PubMed:  24149842|24524803|7622064

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
Ribosomal_L7Ae pfam01248
Ribosomal protein L7Ae/L30e/S12e/Gadd45 family; This family includes: Ribosomal L7A from ...
 108-178 1.49e-08

Ribosomal protein L7Ae/L30e/S12e/Gadd45 family; This family includes: Ribosomal L7A from metazoa, Ribosomal L8-A and L8-B from fungi, 30S ribosomal protein HS6 from archaebacteria, 40S ribosomal protein S12 from eukaryotes, Ribosomal protein L30 from eukaryotes and archaebacteria. Gadd45 and MyD118.


:

Pssm-ID: 426153 [Multi-domain]  Cd Length: 95  Bit Score: 51.06  E-value: 1.49e-08
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 315113850  108 KQLAIGINEVTKGLERNELSLVLVCNSVTPAHMTSHLIPLSKTRSVPACQVPGlSGSLSELLGLK-CVLALG 178
Cdd:pfam01248  14 GKLVLGLKEVTKALERGEAKLVIIAEDCDPEEKVKLIPALCKEKNVPYVKVPS-KKELGEACGKKrPVSALA 84
 
Name Accession Description Interval E-value
Ribosomal_L7Ae pfam01248
Ribosomal protein L7Ae/L30e/S12e/Gadd45 family; This family includes: Ribosomal L7A from ...
 108-178 1.49e-08

Ribosomal protein L7Ae/L30e/S12e/Gadd45 family; This family includes: Ribosomal L7A from metazoa, Ribosomal L8-A and L8-B from fungi, 30S ribosomal protein HS6 from archaebacteria, 40S ribosomal protein S12 from eukaryotes, Ribosomal protein L30 from eukaryotes and archaebacteria. Gadd45 and MyD118.


Pssm-ID: 426153 [Multi-domain]  Cd Length: 95  Bit Score: 51.06  E-value: 1.49e-08
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 315113850  108 KQLAIGINEVTKGLERNELSLVLVCNSVTPAHMTSHLIPLSKTRSVPACQVPGlSGSLSELLGLK-CVLALG 178
Cdd:pfam01248  14 GKLVLGLKEVTKALERGEAKLVIIAEDCDPEEKVKLIPALCKEKNVPYVKVPS-KKELGEACGKKrPVSALA 84
PTZ00365 PTZ00365
60S ribosomal protein L7Ae-like; Provisional
 110-196 8.31e-03

60S ribosomal protein L7Ae-like; Provisional


Pssm-ID: 240382  Cd Length: 266  Bit Score: 36.75  E-value: 8.31e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315113850 110 LAIGINEVTKGLERNELSLVLVCNSVTPAHMTSHLIPLSKTRSVPACQVPGLSgSLSELLGLK--CVLALGFRRGSE--E 185
Cdd:PTZ00365 133 LKYGLNHVTDLVEYKKAKLVVIAHDVDPIELVCFLPALCRKKEVPYCIIKGKS-RLGKLVHQKtaAVVAIDNVRKEDqaE 211

                         90
                 ....*....|.
gi 315113850 186 FENTVRAITPM 196
Cdd:PTZ00365 212 FDNLCKNFRAM 222
Rpl7Ae COG1358
Ribosomal protein L7Ae or related RNA K-turn-binding protein [Translation, ribosomal structure ...
 104-159 8.78e-03

Ribosomal protein L7Ae or related RNA K-turn-binding protein [Translation, ribosomal structure and biogenesis]; Ribosomal protein L7Ae or related RNA K-turn-binding protein is part of the Pathway/BioSystem: Ribosome 50S subunit


Pssm-ID: 440969 [Multi-domain]  Cd Length: 98  Bit Score: 34.75  E-value: 8.78e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 315113850 104 LALR-KQLAIGINEVTKGLERNELSLVLVCNSVTPaHMTSHLIPLSKTRSVPACQVP 159
Cdd:COG1358    9 LARRaGKLVSGEEQVLKAIRKGKAKLVIIAEDASE-NTKKKLLDLCEEYGVPVVEVG 64
 
Name Accession Description Interval E-value
Ribosomal_L7Ae pfam01248
Ribosomal protein L7Ae/L30e/S12e/Gadd45 family; This family includes: Ribosomal L7A from ...
 108-178 1.49e-08

Ribosomal protein L7Ae/L30e/S12e/Gadd45 family; This family includes: Ribosomal L7A from metazoa, Ribosomal L8-A and L8-B from fungi, 30S ribosomal protein HS6 from archaebacteria, 40S ribosomal protein S12 from eukaryotes, Ribosomal protein L30 from eukaryotes and archaebacteria. Gadd45 and MyD118.


Pssm-ID: 426153 [Multi-domain]  Cd Length: 95  Bit Score: 51.06  E-value: 1.49e-08
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 315113850  108 KQLAIGINEVTKGLERNELSLVLVCNSVTPAHMTSHLIPLSKTRSVPACQVPGlSGSLSELLGLK-CVLALG 178
Cdd:pfam01248  14 GKLVLGLKEVTKALERGEAKLVIIAEDCDPEEKVKLIPALCKEKNVPYVKVPS-KKELGEACGKKrPVSALA 84
PTZ00365 PTZ00365
60S ribosomal protein L7Ae-like; Provisional
 110-196 8.31e-03

60S ribosomal protein L7Ae-like; Provisional


Pssm-ID: 240382  Cd Length: 266  Bit Score: 36.75  E-value: 8.31e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315113850 110 LAIGINEVTKGLERNELSLVLVCNSVTPAHMTSHLIPLSKTRSVPACQVPGLSgSLSELLGLK--CVLALGFRRGSE--E 185
Cdd:PTZ00365 133 LKYGLNHVTDLVEYKKAKLVVIAHDVDPIELVCFLPALCRKKEVPYCIIKGKS-RLGKLVHQKtaAVVAIDNVRKEDqaE 211

                         90
                 ....*....|.
gi 315113850 186 FENTVRAITPM 196
Cdd:PTZ00365 212 FDNLCKNFRAM 222
Rpl7Ae COG1358
Ribosomal protein L7Ae or related RNA K-turn-binding protein [Translation, ribosomal structure ...
 104-159 8.78e-03

Ribosomal protein L7Ae or related RNA K-turn-binding protein [Translation, ribosomal structure and biogenesis]; Ribosomal protein L7Ae or related RNA K-turn-binding protein is part of the Pathway/BioSystem: Ribosome 50S subunit


Pssm-ID: 440969 [Multi-domain]  Cd Length: 98  Bit Score: 34.75  E-value: 8.78e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 315113850 104 LALR-KQLAIGINEVTKGLERNELSLVLVCNSVTPaHMTSHLIPLSKTRSVPACQVP 159
Cdd:COG1358    9 LARRaGKLVSGEEQVLKAIRKGKAKLVIIAEDASE-NTKKKLLDLCEEYGVPVVEVG 64
PTZ00222 PTZ00222
60S ribosomal protein L7a; Provisional
 69-197 8.94e-03

60S ribosomal protein L7a; Provisional


Pssm-ID: 140249  Cd Length: 263  Bit Score: 36.60  E-value: 8.94e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315113850  69 SRRRSRKKASKPTEEQNpaSEPAESVQTPEPgwtnLALrkqlAIGINEVTKGLERNELSLVLVCNSVTPAHMTSHLIPLS 148
Cdd:PTZ00222 102 TRKARRDRLHKVAEEKK--KDPKKTVSTKAP----LAV----VTGLQEVTRAIEKKQARMVVIANNVDPVELVLWMPNLC 171

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 315113850 149 KTRSVPACQVPGLSgSLSELLGLKCVLALGFRRGSEEFENTVRAITPMV 197
Cdd:PTZ00222 172 RANKIPYAIVKDMA-RLGDAIGRKTATCVAITDVNAEDEAALKNLIRSV 219
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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