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Conserved domains on  [gi|348041312|ref|NP_001002417|]
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mediator of RNA polymerase II transcription subunit 31 [Danio rerio]

Protein Classification

mediator of RNA polymerase II transcription subunit 31( domain architecture ID 10529302)

mediator of RNA polymerase II transcription subunit 31 is a component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Med31 pfam05669
SOH1; The family consists of Saccharomyces cerevisiae SOH1 homologs. SOH1 is responsible for ...
 12-106 4.44e-56

SOH1; The family consists of Saccharomyces cerevisiae SOH1 homologs. SOH1 is responsible for the repression of temperature sensitive growth of the HPR1 mutant and has been found to be a component of the RNA polymerase II transcription complex. SOH1 not only interacts with factors involved in DNA repair, but transcription as well. Thus, the SOH1 protein may serve to couple these two processes.


:

Pssm-ID: 428575  Cd Length: 95  Bit Score: 170.01  E-value: 4.44e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 348041312   12 RQRFQLELEFVQCLANPNYLNFLAQRGYLREKPFVNYLKYLLYWKEPEYAKFLKYPHCLHMLELLQYEHFRKELVNAQCA 91
Cdd:pfam05669   1 KTRFELELEFVQSLANPQYLNHLAQNGYLEDPAFINYLKYLQYWKEPEYAKFLTYPHCLHFLDLLQNEEFRQEISNPDFA 80

                          90
                  ....*....|....*
gi 348041312   92 KFIDEQQILHWQHYS 106
Cdd:pfam05669  81 KFLMDQQYLHWQTYR 95
 
Name Accession Description Interval E-value
Med31 pfam05669
SOH1; The family consists of Saccharomyces cerevisiae SOH1 homologs. SOH1 is responsible for ...
 12-106 4.44e-56

SOH1; The family consists of Saccharomyces cerevisiae SOH1 homologs. SOH1 is responsible for the repression of temperature sensitive growth of the HPR1 mutant and has been found to be a component of the RNA polymerase II transcription complex. SOH1 not only interacts with factors involved in DNA repair, but transcription as well. Thus, the SOH1 protein may serve to couple these two processes.


Pssm-ID: 428575  Cd Length: 95  Bit Score: 170.01  E-value: 4.44e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 348041312   12 RQRFQLELEFVQCLANPNYLNFLAQRGYLREKPFVNYLKYLLYWKEPEYAKFLKYPHCLHMLELLQYEHFRKELVNAQCA 91
Cdd:pfam05669   1 KTRFELELEFVQSLANPQYLNHLAQNGYLEDPAFINYLKYLQYWKEPEYAKFLTYPHCLHFLDLLQNEEFRQEISNPDFA 80

                          90
                  ....*....|....*
gi 348041312   92 KFIDEQQILHWQHYS 106
Cdd:pfam05669  81 KFLMDQQYLHWQTYR 95
SOH1 COG5088
Rad5p-binding protein [General function prediction only];
14-102 2.05e-28

Rad5p-binding protein [General function prediction only];


Pssm-ID: 227420  Cd Length: 114  Bit Score: 100.34  E-value: 2.05e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 348041312  14 RFQLELEFVQCLANPNYLNFLAQRGYLREKPFVNYLKYLLYWKEPEYAKFLKYPHCLHMLELLQYEHFRKELVNAQCAKF 93
Cdd:COG5088   16 RFEVELEFVQSLANPQYLTLLTQQQIFESENFKNYLKYLEYWRNPEYSQFIVYPNCLFILKLLNGFMESAIVSEDGLLEG 95


                 ....*....
gi 348041312  94 IDEQQILHW 102
Cdd:COG5088   96 LDELQYPQW 104
 
Name Accession Description Interval E-value
Med31 pfam05669
SOH1; The family consists of Saccharomyces cerevisiae SOH1 homologs. SOH1 is responsible for ...
 12-106 4.44e-56

SOH1; The family consists of Saccharomyces cerevisiae SOH1 homologs. SOH1 is responsible for the repression of temperature sensitive growth of the HPR1 mutant and has been found to be a component of the RNA polymerase II transcription complex. SOH1 not only interacts with factors involved in DNA repair, but transcription as well. Thus, the SOH1 protein may serve to couple these two processes.


Pssm-ID: 428575  Cd Length: 95  Bit Score: 170.01  E-value: 4.44e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 348041312   12 RQRFQLELEFVQCLANPNYLNFLAQRGYLREKPFVNYLKYLLYWKEPEYAKFLKYPHCLHMLELLQYEHFRKELVNAQCA 91
Cdd:pfam05669   1 KTRFELELEFVQSLANPQYLNHLAQNGYLEDPAFINYLKYLQYWKEPEYAKFLTYPHCLHFLDLLQNEEFRQEISNPDFA 80

                          90
                  ....*....|....*
gi 348041312   92 KFIDEQQILHWQHYS 106
Cdd:pfam05669  81 KFLMDQQYLHWQTYR 95
SOH1 COG5088
Rad5p-binding protein [General function prediction only];
14-102 2.05e-28

Rad5p-binding protein [General function prediction only];


Pssm-ID: 227420  Cd Length: 114  Bit Score: 100.34  E-value: 2.05e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 348041312  14 RFQLELEFVQCLANPNYLNFLAQRGYLREKPFVNYLKYLLYWKEPEYAKFLKYPHCLHMLELLQYEHFRKELVNAQCAKF 93
Cdd:COG5088   16 RFEVELEFVQSLANPQYLTLLTQQQIFESENFKNYLKYLEYWRNPEYSQFIVYPNCLFILKLLNGFMESAIVSEDGLLEG 95


                 ....*....
gi 348041312  94 IDEQQILHW 102
Cdd:COG5088   96 LDELQYPQW 104
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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