|
Name |
Accession |
Description |
Interval |
E-value |
| 2A060601 |
TIGR00917 |
Niemann-Pick C type protein family; The model describes Niemann-Pick C type protein in ... |
32-1267 |
0e+00 |
|
Niemann-Pick C type protein family; The model describes Niemann-Pick C type protein in eukaryotes. The defective protein has been associated with Niemann-Pick disease which is described in humans as autosomal recessive lipidosis. It is characterized by the lysosomal accumulation of unestrified cholesterol. It is an integral membrane protein, which indicates that this protein is most likely involved in cholesterol transport or acts as some component of cholesterol homeostasis. [Transport and binding proteins, Other]
Pssm-ID: 273337 [Multi-domain] Cd Length: 1205 Bit Score: 886.56 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50300485 32 CTFYEECGknpelsgGLTSLSNVSCLSNTPARHVTGEHLALLQRICPrlYNGPN-TTFACCSTKQLLSLESSMSITKALL 110
Cdd:TIGR00917 1 CAMYDICG-------ARSDGKVLNCPYNIPSVKPPDLLSSLIQSLCQ--YSHPTiSGNVCCTETQFDTLRSNVQQAIPFI 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50300485 111 TRCPACSDNFVSLHCHNTCSPDQSLFINVTRVVERGAGEPPAVVAYeaFYQRSFAEKAYESCSQVRIPAAASLAVGSMCG 190
Cdd:TIGR00917 72 VRCPACLRNFLNLFCELTCSPDQSLFINVTSTTKVKTNSTVDGIQY--YITDDFAAGMYNSCKNVKFGSSNSRALDFLGG 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50300485 191 VYGSAlCNAQRWLNFQGDTGNGLAPLDITFHLLEPGQAlpDGIQPLNGKIAPCNESQGDDSAVCSCQDCAASC-PVIPPP 269
Cdd:TIGR00917 150 GAKNF-KEWFNWIGQKAGVNLPGAPYGIAFLPTPCPVS--SGMRPMNVSIYSCGDESLGCSCGDCPSAATCSCkAKVPTQ 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50300485 270 EALRPSFYMGRmpGWLALII-IFTAVFVLLSAVLVRLRVV----------------SNRNKNKAEGPQEAPKLPHKHKLS 332
Cdd:TIGR00917 227 KKHSCSIKLGV--KCVDFILaILYIVLVSVFLGGGLLHPVrgkkktsqmgtlseadGEINSVNQQKDQNTPQRNWGQLST 304
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50300485 333 PHTILGRFFQNWGTRVASWPLTVLALSFIVVIALAAGLTFIELTTDPVELWSAPKSQARKEKSFHDEHFGPFFRTNQIFV 412
Cdd:TIGR00917 305 VQGHLARFFGKYGIWVARHPTLVICLSVSVVLLLCVGLIRFKVETRPVKLWVAPGSRAALEKQYFDTHFGPFYRIEQLII 384
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50300485 413 TARNRSSYKYDSLLLGSKNFSGILSLDFLLEllelqerlrhlQVWSPEAERNISLQDICYAPLNPYNtslsdCCVNSLLQ 492
Cdd:TIGR00917 385 ATVQTSSHEKAPEILTDDNLKLLFDIQKKVS-----------QLFANYEGELITLDSPCFKPNHPYN-----CFIYSTCK 448
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50300485 493 YFQNNRTLLmltaNQTLNGQTSLVDWKDHFLYCANAPLtfkdgtslalSCMADYGAPVFPFLAVGGYQGTDYSEAEALII 572
Cdd:TIGR00917 449 KLQNMYSKL----KPENYDDYGGVDYVKYCFEHFTSPE----------SCLSAFGGPVDPTTVLGGFSGNNFSEASAFVV 514
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50300485 573 TFSLNNYPADDPRMAQAKLWEEAFLKEMESFqRNTSDKFQVAFSAERSLEDEINRTTIQDLPVFAVSYIIVFLYISLALG 652
Cdd:TIGR00917 515 TFPVNNFVNKTNKTEKAVAWEKAFIQLAKDE-LLPMVQATISFSAERSIEDELKRESTADVITIAISYLVMFAYISLTLG 593
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50300485 653 SYSRCSRVAVESKATLGLGGVIVVLGAVLAAMGFYSYLGVPSSLVIIQVVPFLVLAVGADNIFIFVLEYQRLPRMPGEQR 732
Cdd:TIGR00917 594 DSPRLKSLYVTSKVLLGLSGILIVMLSVLGSVGVFSAVGLKSTLIIMEVIPFLVLAVGVDNIFILVFFYFYLEYFYRQVG 673
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50300485 733 ---------EAHIGRTLGSVAPSMLLCSLSEAICFFLGALTPMPAVRTFALTSGLAIILDFLLQMTAFVALLSLDSKRQE 803
Cdd:TIGR00917 674 vdneqeltlERRLSRALMEVGPSITLASLSEILAFALGALIKMPAVRVFSMFAVLAVFLDFLLQITAFVALLVLDFKRTE 753
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50300485 804 ASRPDVLCCFSTRKLPPPKE------KEGLLLRFFRKIYAPFLLHRFIRPVVMLLFLTLFGANLYLMCNINVGLDQELAL 877
Cdd:TIGR00917 754 DKRVDCFPCIKTSKSSISAEkgsgqrKAGLLTRYFKEVYAPVLLHWIVKIVVIAFFVGLLMAGIALSTRVEIGLDQQIVL 833
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50300485 878 PKDSYLIDYFLFLNRYLEVGPPVYFVTTSGFNFSSEAGMNATCSSAGCKSFSLTQkiqyasEFPDQSYVAIAASSWVDDF 957
Cdd:TIGR00917 834 PQDSYLQIYFASLTPLLEVGPPFYIVIKGDYNYTDFESQNKLCTMGGCDKDSIVN------VFNNLSYIAKPASSWLDDY 907
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50300485 958 IDWLTPSSSCCRLYirgPHKDEFCPSTDTSfnCLKNCMNRTLGPVRPTAEQFHKYLPWFLNDPPNIRCPKGGLAAYRTSV 1037
Cdd:TIGR00917 908 LVWLSPQASCCCRK---FTNGTFCNGPDPQ--CFRCADLSSDAQGRPSTTQFKEKLPWFLNALPSADCAKGGHAAYSSAV 982
|
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50300485 1038 NLSSDGQVI-ASQFMAYHKPLRNSQDFTEALRASRLLAANITADLRkvpgtdpnFEVFPYTISNVFYQQYLTVLPEGIFT 1116
Cdd:TIGR00917 983 DLQGYATIIqASSFRTYHTPLNTQVDFINAMRAAQEFAAKVSRSSK--------MEVYPYSVFYVFFEQYLTIWKTAIIN 1054
|
1130 1140 1150 1160 1170 1180 1190 1200
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50300485 1117 LALCFVPTFVVCYLLLGLDMCSGILNLLSIIMILVDTIGLMAVWGISYNAVSLINLVTAVGMSVEFVSHITRSFAVSTKP 1196
Cdd:TIGR00917 1055 LSIALGAIFIVCLFLLQLNALSVVNLIMSVGMAVVFCVGIMHLWSISLNAVSVVNSVMHKGIAIEFCTHINAQFSTGKHF 1134
|
1210 1220 1230 1240 1250 1260 1270
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 50300485 1197 TRLERAKDATVFMGSAVFAGVAMTNFPGILILGFAQAQLIQIFFFRLNLLITLLGLLHGLVFLPVVLSYLG 1267
Cdd:TIGR00917 1135 SRNHRAKEALGGMGSSVFSGITLTKLVGVVVLGFSRSEIFVVYYFRMYLALVLLGFLHGLVFLPVLLSVLG 1205
|
|
| NPC1_N |
pfam16414 |
Niemann-Pick C1 N terminus; This is the N-terminal domain of Niemann-Pick C1 family proteins. ... |
30-283 |
8.18e-93 |
|
Niemann-Pick C1 N terminus; This is the N-terminal domain of Niemann-Pick C1 family proteins. This family of proteins mediates transport of cholesterol from the intestinal lumen to enterocytes. This domain contains a cholesterol-binding pocket.
Pssm-ID: 465110 Cd Length: 239 Bit Score: 298.75 E-value: 8.18e-93
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50300485 30 GVCTFYEECGKNPELSggltslSNVSCLSNTPARHVTGEHLALLQRICPRLYNgpNTTFACCSTKQLLSLESSMSITKAL 109
Cdd:pfam16414 1 GRCAWYGECGKKSLFG------KDLPCPYNGPAKPLDDEVRDLLAELCPLLFA--DETPVCCDADQLNTLRSNLKLAEGL 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50300485 110 LTRCPACSDNFVSLHCHNTCSPDQSLFINVTRVVERGAGEpPAVVAYEAFYQRSFAEKAYESCSQVRIPAAASLAVGSMC 189
Cdd:pfam16414 73 LSRCPACKKNFANLFCEFTCSPNQSTFLNVTKTKKSVDGK-EYVTELDYYISEEYASGFYDSCKDVKFPATNGYAMDLIC 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50300485 190 GVYgsalCNAQRWLNFQGDTGNGLAPLDITFHLlePGQALPDGIQPLNGKIAPCNESQgDDSAVCSCQDCAASCPVIPPP 269
Cdd:pfam16414 152 GGA----CNYTRWLKFMGDKKNGGSPFQINFPD--PPEEDPSGMVPLNPNTKDCNESY-DASYACSCVDCPLSCPPPPQL 224
|
250
....*....|....*
gi 50300485 270 EALRP-SFYMGRMPG 283
Cdd:pfam16414 225 PPPPHgPCKVGGLDG 239
|
|
| Patched |
pfam02460 |
Patched family; The transmembrane protein Patched is a receptor for the morphogene Sonic ... |
549-1240 |
7.65e-64 |
|
Patched family; The transmembrane protein Patched is a receptor for the morphogene Sonic Hedgehog. This protein associates with the smoothened protein to transduce hedgehog signals.
Pssm-ID: 308203 [Multi-domain] Cd Length: 793 Bit Score: 233.40 E-value: 7.65e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50300485 549 PVFPFLAVGGYQGTDY-----------SEAEALIITFSLNnypADDPRMAQ-AKLWEEAFLKEMEsfQRNTSDKFQVAFS 616
Cdd:pfam02460 125 PIMPVLGTPIYLGPHFggvdfeppgniSYAKAIVLWYFLK---FDEEEVEEdSKEWEDELSQLLH--NKYASEHIQFTIF 199
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50300485 617 AERSLEDEINRTTIQDLPVFAVSYIIVFLYISLALGSYSRCSRVAVESKATLGLGGVIVVLGAVLAAMGFYSYLGVPSSl 696
Cdd:pfam02460 200 HDQILNDELVRNALTLTPFFVIGFFLLLTFSIIVSVTLSSYTIDWVRSKPILAALGLLSPVMAIVSSFGLLFWMGFPFN- 278
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50300485 697 VIIQVVPFLVLAVGADNIFIFVLEYQRL-PRMPGEQReahIGRTLGSVAPSMLLCSLSEAICFFLGALTPMPAVRTFALT 775
Cdd:pfam02460 279 SIVCVTPFLVLAIGVDDMFLMVAAWQRTtATLSVKKR---MGEALSEAGVSITITSLTDVLSFGIGTYTPTPAIQLFCAY 355
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50300485 776 SGLAIILDFLLQMTAFVALLSLDSKRQEASRPDVLC--------CFSTRKLPPPKEK-EGLLLRFFRKIYAPFLLHRFIR 846
Cdd:pfam02460 356 TAVAIFFDFIYQITFFAAIMAICAKPEAEGRHCLFVwatsspqrIDSEGSEPDKSHNiEQLKSRFFLDIYCPFLLNPSVR 435
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50300485 847 PVVMLLFLTLFGANLYLMCNINVGLDQELALPKDSYLIDYF-----LFLNRYLEV-----GPPVYfvttsgFNFSSEAGM 916
Cdd:pfam02460 436 VCMLVLFVVYIAIAIYGCVNIKEGLEPDKLVLEDSPLVEYLslrekHFWPEGLQIqvavnNPPNL------TIPESRDRM 509
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50300485 917 NATCSsagckSFSLTQKI--QYASEFpdqsyvaiaassWVDDFIDWLTPSSSCCRLYIRGPhkdefcpstdTSFNCLKNC 994
Cdd:pfam02460 510 NEMVD-----EFENTPYSlgPNSTLF------------WLREYENFLSTLNMEEEEDEEKE----------WSYGNLPSF 562
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50300485 995 MnrtLGPVRPTAEQFHKYlpwflNDppnircpkgglaayrtsvnlsSDGQVIASQFMAYHKPLRNSQDFTEALRasrlla 1074
Cdd:pfam02460 563 L---KAPGNSHWAGDLVW-----DD---------------------NTTMVTKFRFTLAGKGLSTWNDRTRALQ------ 607
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50300485 1075 anitaDLRKVPGTDPNFEVFPYTISNVFYQQYLTVLPEGIFTLALCFVPTFVVCYLLLGLDMCSGILnLLSIIMILVDTI 1154
Cdd:pfam02460 608 -----EWRSIADQYPEFNVTVFDEDAPFADQYLTILPSTIQNIVITLICMFIVCFLFIPNPPCVFVI-TLAIASIDIGVF 681
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50300485 1155 GLMAVWGISYNAVSLINLVTAVGMSVEFVSHITRSFAVSTKPTRLERAKDATVFMGSAVFAGvAMTNFPGILILGFAQAQ 1234
Cdd:pfam02460 682 GFLSLWGVDLDPISMITIIMSIGFSVDFSAHIAYHFVRSRGDTPAERVVDALEALGWPVFQG-GLSTILGVLVLLFVPSY 760
|
....*.
gi 50300485 1235 LIQIFF 1240
Cdd:pfam02460 761 MVVVFF 766
|
|
| Sterol-sensing |
pfam12349 |
Sterol-sensing domain of SREBP cleavage-activation; Sterol regulatory element-binding proteins ... |
661-815 |
1.09e-58 |
|
Sterol-sensing domain of SREBP cleavage-activation; Sterol regulatory element-binding proteins (SREBPs) are membrane-bound transcription factors that promote lipid synthesis in animal cells. They are embedded in the membranes of the endoplasmic reticulum (ER) in a helical hairpin orientation and are released from the ER by a two-step proteolytic process. Proteolysis begins when the SREBPs are cleaved at Site-1, which is located at a leucine residue in the middle of the hydrophobic loop in the lumen of the ER. Upon proteolytic processing SREBP can activate the expression of genes involved in cholesterol biosynthesis and uptake. SCAP stimulates cleavage of SREBPs via fusion of the their two C-termini. This domain is the transmembrane region that traverses the membrane eight times and is the sterol-sensing domain of the cleavage protein. WD40 domains are found towards the C-terminus.
Pssm-ID: 463544 [Multi-domain] Cd Length: 153 Bit Score: 198.96 E-value: 1.09e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50300485 661 AVESKATLGLGGVIVVLGAVLAAMGFYSYLGVPSSLVIIQVVPFLVLAVGADNIFIFVLEYQRLPRMPGEqrEAHIGRTL 740
Cdd:pfam12349 1 MVKSKFGLGLAGVIIVLASVASSLGLCAYFGLPLTLIISEVIPFLVLAIGVDNIFLLVKAVVRTPRSLDV--SERIAEAL 78
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 50300485 741 GSVAPSMLLCSLSEAICFFLGALTPMPAVRTFALTSGLAIILDFLLQMTAFVALLSLDSKRQEASRPDVLCCFST 815
Cdd:pfam12349 79 GEVGPSITLTSLTEILAFLLGALTDMPAVQEFCLFAAVAVLFDFLLQMTFFVAVLSLDIRRLESNRLDVACCIRV 153
|
|
| 2A060602 |
TIGR00918 |
The Eukaryotic (Putative) Sterol Transporter (EST) Family; |
592-1290 |
1.28e-48 |
|
The Eukaryotic (Putative) Sterol Transporter (EST) Family;
Pssm-ID: 273338 [Multi-domain] Cd Length: 1145 Bit Score: 189.71 E-value: 1.28e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50300485 592 WEEAFLKEMESFQRNTSDKFQVAFSAErSLEDEINRTTIQDLPVFAVSYIIVFLYISLALGSYSrcsrvAVESKATLGLG 671
Cdd:TIGR00918 359 WQRNFSEEVQQSLPKNSSQKILVFSST-TLDDILKKFSDVSAIRIVSGYLLMLAYACLTMLRWD-----CAKSQGSVGLA 432
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50300485 672 GVIVVLGAVLAAMGFYSYLGVPSSLVIIQVVPFLVLAVGADNIFIFVLEY-QRLPRMPGEQReahIGRTLGSVAPSMLLC 750
Cdd:TIGR00918 433 GVLLVALSVAAGLGLCALLGISFNAATTQVLPFLALGVGVDDVFLLAHAFsETGQNIPFEER---TGECLKRTGASVVLT 509
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50300485 751 SLSEAICFFLGALTPMPAVRTFALTSGLAIILDFLLQMTAFVALLSLDSKRQEASRPDVLCCF----------------- 813
Cdd:TIGR00918 510 SISNVTAFFMAALIPIPALRAFSLQAAIVVVFNFAAVLLVFPAILSLDLRRREDRRLDIFCCFfspcsarviqiepqaya 589
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50300485 814 --------------------------------------------------------STRKLPPPKEKEGL---------- 827
Cdd:TIGR00918 590 dgsappvysshmqstvqlrteydpgtqhyyttneprshlsvqpsdplscqspdiagSTRDLLSQFEDSKAaclslpcarw 669
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50300485 828 -LLRFFRKIYAPFLLHRFIRPVVMLLFLTLFGANLYLMCNINVGLDQELALPKDSYLIDYFLFLNRYLEVgPPVYFVTTS 906
Cdd:TIGR00918 670 tLATFAEKHYAPFLLQSWAKVVVIFLFLALLGLSLYGTTRVQDGLDLTDIVPRDTNEHDFLDAQFRYFSF-YNMYAVTQG 748
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50300485 907 GFNFSSEAGMNATCSsagcKSFSLTQKI--QYASEFPD----------QSYVAIAASSWVDDFI---DWLTPSSSCC--- 968
Cdd:TIGR00918 749 NFDYPTQQQLLYDLH----QSFSSVKYVlkEDNGQLPRmwlhyfrdwlQGLQKAFDEDWRDGRItkeNYRNGSDDAVlay 824
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50300485 969 RLYIRGPHKDEfcpSTDTSFNCLKNCMNRTlGPVRPTAeqFHKYLP-WFLNDPPNIRCPKGGLAAYR------------T 1035
Cdd:TIGR00918 825 KLLVQTGHRDK---PVDKEQLTTQRLVNAD-GIINPNA--FYIYLSaWVSNDPVAYAASQANIYPHPpewlhdkndydpE 898
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50300485 1036 SVNLSSDGQVIASQFMAYHKPLRNSQDFTEALRASRLLAANITAdlRKVPGtdpnfevFPYTISNVFYQQYLTVLPEGIF 1115
Cdd:TIGR00918 899 NLRIPAAEPLEYAQFPFYLNGLRETSQFVEAIEHVRAICNNYEG--FGLPS-------YPSGYPFLFWEQYMGLRHWLLL 969
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50300485 1116 TLALCFVPTFVVCYLLLgLDMCSGILNLLSIIMILVDTIGLMAVWGISYNAVSLINLVTAVGMSVEFVSHITRSFaVSTK 1195
Cdd:TIGR00918 970 SISVVLACTFLVCALLL-LNPWTAGLIVLVLALMTVELFGMMGLLGIKLSAIPVVILIASVGIGVEFTVHIALGF-LTAI 1047
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50300485 1196 PTRLERAKDATVFMGSAVFAGvAMTNFPGILILGFAQAQLIQIFFFRLNLLITLLGLLHGLVFLPVVLSYLGPDVNqaLV 1275
Cdd:TIGR00918 1048 GDRNRRAVLALEHMFAPVLDG-ALSTLLGVLMLAGSEFDFIVRYFFAVLAVLTCLGVLNGLVLLPVLLSMFGPEPE--VS 1124
|
810
....*....|....*
gi 50300485 1276 QEEKLASEAAVAPEP 1290
Cdd:TIGR00918 1125 PAEGRSRLPTPSPEP 1139
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
558-1239 |
9.00e-26 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 114.96 E-value: 9.00e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50300485 558 GYQGTDYSE-AEALIITFSLNNYPADDPRMAqaklweEAFLKEMESF-QRNTSDKFQVAFSAERSLEDEINRTTIQDLPV 635
Cdd:COG1033 149 LYVGRLVSPdGKATLIVVTLDPDPLSSDLDR------KEVVAEIRAIiAKYEDPGVEVYLTGFPVLRGDIAEAIQSDLAI 222
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50300485 636 F-AVSYIIVFLYISLALGSYSrcsrvaveskatLGLGGVIVVLGAVLAAMGFYSYLGVPSSLVIIqVVPFLVLAVGADNI 714
Cdd:COG1033 223 FfPLALLLILLLLFLFFRSLR------------GVLLPLLVVLLAVIWTLGLMGLLGIPLSPLTI-LVPPLLLAIGIDYG 289
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50300485 715 FIFVLEYQRLPRMPGEQREAhIGRTLGSVAPSMLLCSLSEAICFFLGALTPMPAVRTFALTSGLAIILDFLLQMTAFVAL 794
Cdd:COG1033 290 IHLLNRYREERRKGLDKREA-LREALRKLGPPVLLTSLTTAIGFLSLLFSDIPPIRDFGIVAAIGVLLAFLTSLTLLPAL 368
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50300485 795 LSLDSKRQEASRpdvlccfstrklppPKEKEGLLLRFFRKIyAPFLLHRfiRPVVMLLFLTLFGANLYLMCNINVGLDQE 874
Cdd:COG1033 369 LSLLPRPKPKTR--------------RLKKPPELGRLLAKL-ARFVLRR--PKVILVVALVLAVVSLYGISRLKVEYDFE 431
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50300485 875 LALPKDS-YLIDYFLFLNRylevgppvyFVTTSGFNFSSEAGmnatcSSAGCKSFSLTQKI----QYASEFPDqsyvaIA 949
Cdd:COG1033 432 DYLPEDSpIRQDLDFIEEN---------FGGSDPLEVVVDTG-----EPDGLKDPEVLKEIdrlqDYLESLPE-----VG 492
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50300485 950 ASSWVDDFIDWLTpsssccRLYIRGPHKDefcpstdtsfnclkncmnRTLGPVRPTAEQfhkYLPWFLNDPPNIrcpkgg 1029
Cdd:COG1033 493 KVLSLADLVKELN------QALNEGDPKY------------------YALPESRELLAQ---LLLLLSSPPGDD------ 539
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50300485 1030 LAAYrtsvnLSSDGQviASQFMAYHKPLRNSQ--DFTEALRAsrLLAANITADLRKVPGTDpNFEVFPYTISNVFYQQyl 1107
Cdd:COG1033 540 LSRF-----VDEDYS--AARVTVRLKDLDSEEikALVEEVRA--FLAENFPPDGVEVTLTG-SAVLFAAINESVIESQ-- 607
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50300485 1108 tvlpegIFTLALCFVPTFVVCYLLLGlDMCSGILNLLSIIMILVDTIGLMAVWGISYNAVSLINLVTAVGMSVEFVSHIT 1187
Cdd:COG1033 608 ------IRSLLLALLLIFLLLLLAFR-SLRLGLISLIPNLLPILLTFGLMGLLGIPLNIATAVVASIALGIGVDYTIHFL 680
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 50300485 1188 RSFavstkptRLERAKDATVFM---------GSAVFaGVAMTNFPGILILGFAQAQLIQIF 1239
Cdd:COG1033 681 SRY-------REERRKGGDLEEairralrttGKAIL-FTSLTLAAGFGVLLFSSFPPLADF 733
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
283-797 |
3.13e-13 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 74.51 E-value: 3.13e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50300485 283 GWLALI---IIFTAVFVLLSAVLVRLRvvsnrnknkaegpqeaPKLPHKHKLSPHTILGRFFQNWGTRVASWPLTVLALS 359
Cdd:COG1033 347 GIVAAIgvlLAFLTSLTLLPALLSLLP----------------RPKPKTRRLKKPPELGRLLAKLARFVLRRPKVILVVA 410
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50300485 360 FIVVIALAAGLTFIELTTDPVElWSAPKSQARKEKSFHDEHFGpffRTNQIFVtarnrssykydslLLGSKNFSGILsld 439
Cdd:COG1033 411 LVLAVVSLYGISRLKVEYDFED-YLPEDSPIRQDLDFIEENFG---GSDPLEV-------------VVDTGEPDGLK--- 470
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50300485 440 fllellelqerlrhlqvwSPEAERNI-SLQDicYAPLNPYNTSlsdccVNSLLQYFQnnrtllmlTANQTLNGQtslvDW 518
Cdd:COG1033 471 ------------------DPEVLKEIdRLQD--YLESLPEVGK-----VLSLADLVK--------ELNQALNEG----DP 513
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50300485 519 KDHFLycanaPLTfKDGTSLALSCMADYGAPVFPflavgGYQGTDYSEAealIITFSLNNYPADDprmaqaklwEEAFLK 598
Cdd:COG1033 514 KYYAL-----PES-RELLAQLLLLLSSPPGDDLS-----RFVDEDYSAA---RVTVRLKDLDSEE---------IKALVE 570
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50300485 599 EMESF--QRNTSDKFQVAFSAERSLEDEINRTTIQDLP-VFAVSYIIVFLYISLALGSYSrcsrvaveskatLGLGGVIV 675
Cdd:COG1033 571 EVRAFlaENFPPDGVEVTLTGSAVLFAAINESVIESQIrSLLLALLLIFLLLLLAFRSLR------------LGLISLIP 638
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50300485 676 VLGAVLAAMGFYSYLGVPSSLVIIQVVPfLVLAVGADNiFIFVLEYQRLPRMPGEQREAHIGRTLGSVAPSMLLCSLSEA 755
Cdd:COG1033 639 NLLPILLTFGLMGLLGIPLNIATAVVAS-IALGIGVDY-TIHFLSRYREERRKGGDLEEAIRRALRTTGKAILFTSLTLA 716
|
490 500 510 520
....*....|....*....|....*....|....*....|..
gi 50300485 756 ICFFLGALTPMPAVRTFALTSGLAIILDFLLQMTAFVALLSL 797
Cdd:COG1033 717 AGFGVLLFSSFPPLADFGLLLALGLLVALLAALLLLPALLLL 758
|
|
| COG4258 |
COG4258 |
Predicted exporter [General function prediction only]; |
637-786 |
1.23e-08 |
|
Predicted exporter [General function prediction only];
Pssm-ID: 443400 [Multi-domain] Cd Length: 783 Bit Score: 59.48 E-value: 1.23e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50300485 637 AVSYIIVFLYISLALGSYSRCSRVaveskatlglggVIVVLGAVLAAMGFYSYLGVPSSLVIIqVVPFLVLAVGADNIfI 716
Cdd:COG4258 646 LLALLLILLLLLLRLRSLRRALRV------------LLPPLLAVLLTLAILGLLGIPLNLFHL-IALLLVLGIGIDYA-L 711
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50300485 717 FVLEyqrlprmpGEQREAHIGRTLGSVapsmLLCSLSEAICFFLGALTPMPAVRTFALTSGLAIILDFLL 786
Cdd:COG4258 712 FFTE--------GLLDKGELARTLLSI----LLAALTTLLGFGLLAFSSTPALRSFGLTVLLGILLALLL 769
|
|
| MMPL |
pfam03176 |
MMPL family; Members of this family are putative integral membrane proteins from bacteria. ... |
637-801 |
1.42e-07 |
|
MMPL family; Members of this family are putative integral membrane proteins from bacteria. Several of the members are mycobacterial proteins. Many of the proteins contain two copies of this aligned region. The function of these proteins is not known, although it has been suggested that they may be involved in lipid transport.
Pssm-ID: 308676 [Multi-domain] Cd Length: 332 Bit Score: 54.99 E-value: 1.42e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50300485 637 AVSYIIVFLYISLALGSYsrcsrVAveskATLGLGGVIVVLGAVLAAMGFYSY---LGVPSSLVIIQVVpfLVLAVGAD- 712
Cdd:pfam03176 149 AVTLVVIFIILLIVYRSV-----VA----ALLPLLTVGLSLGAAQGLVAILAHilgIGLSTFALNLLVV--LLIAVGTDy 217
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50300485 713 NIFIfVLEYQRLPRMpGEQREAHIGRTLGSVAPSMLLCSLSEAICFFLGALTPMPAVRTFALTSGLAIILDFLLQMTAFV 792
Cdd:pfam03176 218 ALFL-VSRYREELRA-GEDREEAVIRAVRGTGKVVTAAGLTVAIAMLALSFARLPVFAQVGPTIAIGVLVDVLAALTLLP 295
|
....*....
gi 50300485 793 ALLSLDSKR 801
Cdd:pfam03176 296 ALLALLGRW 304
|
|
| 2A067 |
TIGR00921 |
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ... |
618-880 |
2.51e-07 |
|
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273340 [Multi-domain] Cd Length: 719 Bit Score: 55.23 E-value: 2.51e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50300485 618 ERSLEDEINRTTiqdlpvfAVSYIIVFLyisLALGSYSRCSRvaveskatlGLGGVIVVLGAVLAAMGFYSYLGVPSSLV 697
Cdd:TIGR00921 188 EREFGKDMGTTM-------AISGILVVL---VLLLDFKRWWR---------PLLPLVIILFGVAWVLGIMGWLGIPLYAT 248
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50300485 698 IIQVVPfLVLAVGADNIfIFVLEyqrlpRMpgeQREAHIGRTLGS--------VAPSMLLCSLSEAICFFLGALTPMPAV 769
Cdd:TIGR00921 249 TLLAVP-MLIGVGIDYG-IQTLN-----RY---EEERDIGRAKGEaivtavrrTGRAVLIALLTTSAGFAALALSEFPMV 318
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50300485 770 RTFALTSGLAIILDFLLQMTAFVALL-SLDSKRQEASRPDVLCcfstrklpppKEKEGLLLRFFRKIYAPFLLHrfirPV 848
Cdd:TIGR00921 319 SEFGLGLVAGLITAYLLTLLVLPALLqSIDIGREKVKKEIIAI----------GGKSSEIEEELSKVLSITVRH----PV 384
|
250 260 270
....*....|....*....|....*....|...
gi 50300485 849 VMLLFLTLF-GANLYLMCNINVGLDQELALPKD 880
Cdd:TIGR00921 385 PALVAALIItGLGLYGAAGIKPEVNIEKFIPQD 417
|
|
| 2A067 |
TIGR00921 |
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ... |
670-797 |
5.85e-06 |
|
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273340 [Multi-domain] Cd Length: 719 Bit Score: 50.99 E-value: 5.85e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50300485 670 LGGVIVVLGAVLAAMGFYSYLGVPSSLvIIQVVPFLVLAVGADnIFIFVLEYQRlprmpgEQREAH-----IGRTLGSVA 744
Cdd:TIGR00921 595 VFPLIAIGSGILWAIGLMGLRGIPSFL-AMATTISIILGLGMD-YSIHLAERYF------EERKEHgpkeaITHTMERTG 666
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 50300485 745 PSMLLCSLSEAICFFLGALTPMPAVRTFALTSGLAIILDFLLQMTAFVALLSL 797
Cdd:TIGR00921 667 PGILFSGLTTAGGFLSLLLSHFPIMRNFGLVQGIGVLSSLTAALVVFPALLVL 719
|
|
| HpnN |
TIGR03480 |
hopanoid biosynthesis associated RND transporter like protein HpnN; The genomes containing ... |
611-864 |
8.55e-06 |
|
hopanoid biosynthesis associated RND transporter like protein HpnN; The genomes containing members of this family share the machinery for the biosynthesis of hopanoid lipids. Furthermore, the genes of this family are usually located proximal to other components of this biological process. The proteins appear to be related to the RND family of export proteins, particularly the hydrophobe/amphiphile efflux-3 (HAE3) family represented by TIGR00921.
Pssm-ID: 274598 [Multi-domain] Cd Length: 862 Bit Score: 50.38 E-value: 8.55e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50300485 611 FQVAFSAERSLEDEINRTTIQDLPVFAV-SYIIVFLYISLALGSYsrcsRVAVESKATLGLGgVIVVLGAVLAAMGfysy 689
Cdd:TIGR03480 249 VTVRLTGEVALSDEELATVSEGATVAGLlSFVLVLVLLWLALRSP----RLVFAVLVTLIVG-LILTAAFATLAVG---- 319
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50300485 690 lgvpsSLVIIQVVpFLVLAVG--ADNIFIFVLEYQRLPRMPGEQREAhIGRTLGSVAPSMLLCSLSEAICFFLGALTPMP 767
Cdd:TIGR03480 320 -----HLNLISVA-FAVLFIGlgVDFAIQFSLRYREERFRGGNHREA-LSVAARRMGAALLLAALATAAGFFAFLPTDYK 392
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50300485 768 AVRTFALTSGLAIILDFLLQMTAFVALLSLdskrqeaSRPdvlccfSTRKLPPPKEKEGLLLRFfrkiyapflLHRFIRP 847
Cdd:TIGR03480 393 GVSELGIIAGTGMFIALFVTLTVLPALLRL-------LRP------PRRRKPPGYATLAPLDAF---------LRRHRRP 450
|
250
....*....|....*..
gi 50300485 848 VVMlLFLTLFGANLYLM 864
Cdd:TIGR03480 451 VLG-VTLILGIAALALL 466
|
|
| YdfJ |
COG2409 |
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function ... |
283-415 |
4.43e-05 |
|
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function prediction only];
Pssm-ID: 441964 [Multi-domain] Cd Length: 697 Bit Score: 47.84 E-value: 4.43e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50300485 283 GWLALIIIFTAVFV---LLSAVLVRL--RVvsnrnknkaegpqEAPKLPHKHKLSPHTilGRFFQNWGTRVASWPLTVLA 357
Cdd:COG2409 301 GPAAAIGVAVAVLAaltLLPALLALLgrRV-------------FWPRRPRRRRAAAPE--SGFWRRLARAVVRRPVPVLV 365
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 50300485 358 LSFIVVIALAAGLTFIELTTDPVElwSAPK-SQARkeKSFH--DEHFGPFFrTNQIFVTAR 415
Cdd:COG2409 366 AAVAVLLALALPALGLRLGLPDAD--SLPAdSPSR--QGYDalAEHFPPGS-NGPLTVVVE 421
|
|
| YdfJ |
COG2409 |
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function ... |
670-881 |
1.68e-04 |
|
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function prediction only];
Pssm-ID: 441964 [Multi-domain] Cd Length: 697 Bit Score: 45.91 E-value: 1.68e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50300485 670 LGGVIVVLGAVLAAMGFYSYLGVPSSLVIIQVVpfLVLAVGAD-NIFIFVLEYQRLPRmpGEQREAHIGRTLGSVAPSML 748
Cdd:COG2409 201 LTAGLAVGVALGLLALLAAFTDVSSFAPNLLTM--LGLGVGIDyALFLVSRYREELRA--GEDREEAVARAVATAGRAVL 276
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50300485 749 LCSLSEAICFFLGALTPMPAVRTFALTSGLAIILDFLLQMTAFVALLSLDSKRqeASRPDVlccfstRKLPPPKEKEGll 828
Cdd:COG2409 277 FSGLTVAIALLGLLLAGLPFLRSMGPAAAIGVAVAVLAALTLLPALLALLGRR--VFWPRR------PRRRRAAAPES-- 346
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 50300485 829 lRFFRKIyAPFLLHrfiRPV-VMLLFLTLFGANLYLMCNINVGLDQELALPKDS 881
Cdd:COG2409 347 -GFWRRL-ARAVVR---RPVpVLVAAVAVLLALALPALGLRLGLPDADSLPADS 395
|
|
| ACR_tran |
pfam00873 |
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ... |
1115-1238 |
3.21e-04 |
|
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.
Pssm-ID: 395701 [Multi-domain] Cd Length: 1021 Bit Score: 45.36 E-value: 3.21e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50300485 1115 FTLALCFVPTFVVCYLLLGlDMCSGILNLLSIIMILVDTIGLMAVWGISYNAVSLINLVTAVGMSVE----FVSHITRSF 1190
Cdd:pfam00873 335 KTLLEAIVLVILVMFLFLQ-NWRATLIPAIAIPLSLLGTFAVMKAFGFSINTLTLGGLVLAIGLVVDdaivVVENIERVL 413
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 50300485 1191 AVSTKPTR---------LERAKDATVFMGSAVFAGVA-MTNFPGILILGFAQAQLIQI 1238
Cdd:pfam00873 414 EENGLKPLeaayksmgeIGGALVAIALVLSAVFLPILfLGGLTGRIFRQFAITIVLAI 471
|
|
| 2A067 |
TIGR00921 |
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ... |
1139-1240 |
4.56e-03 |
|
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273340 [Multi-domain] Cd Length: 719 Bit Score: 41.36 E-value: 4.56e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50300485 1139 GILNLLSIIMILVDTIGLMAVWGISYNAVSLINLVTAVGMSVEFVSHITRSF------------AVSTKPTRLERAKDAT 1206
Cdd:TIGR00921 220 PLLPLVIILFGVAWVLGIMGWLGIPLYATTLLAVPMLIGVGIDYGIQTLNRYeeerdigrakgeAIVTAVRRTGRAVLIA 299
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 50300485 1207 VFMGSAVFAGVAMTNFPGI------LILGFAQAQLIQIFF 1240
Cdd:TIGR00921 300 LLTTSAGFAALALSEFPMVsefglgLVAGLITAYLLTLLV 339
|
|
| |
