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Conserved domains on  [gi|403531838|ref|YP_006666179|]
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NADH dehydrogenase subunit 6 (mitochondrion) [Petrotilapia nigra]

Protein Classification

NADH dehydrogenase subunit 6( domain architecture ID 10009582)

NADH dehydrogenase subunit 6 (mitochondrion) is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 1-173 4.09e-84

NADH dehydrogenase subunit 6; Provisional


:

Pssm-ID: 177196  Cd Length: 173  Bit Score: 245.05  E-value: 4.09e-84
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531838   1 MVYIMFMFLLGLVVGLAAVASNPSPYFAALGLVVVAGMGCGVLVGHGGSFLSLILFLIYLGGMLVVFAYSAALAAEPYPE 80
Cdd:MTH00138   1 MTYLMSLFLLGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531838  81 GWGSWPVLGVMVAYLLGVGMAAVLFWGGWYEGAWVSADEFVEFSVFRGDVGGVALMYSMGGGVLVMGAWVLLLTLFVVLE 160
Cdd:MTH00138  81 SWGSWSVLGYVVGYLVGVVLAAGLFWGGWYEGSWVVVDELKEFSVLRGDVGGVALMYSSGGGMLVICAWVLLLTLFVVLE 160

                        170
                 ....*....|...
gi 403531838 161 LTRGLSRGALRAV 173
Cdd:MTH00138 161 LTRGLSRGALRAV 173
 
Name Accession Description Interval E-value
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 1-173 4.09e-84

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 177196  Cd Length: 173  Bit Score: 245.05  E-value: 4.09e-84
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531838   1 MVYIMFMFLLGLVVGLAAVASNPSPYFAALGLVVVAGMGCGVLVGHGGSFLSLILFLIYLGGMLVVFAYSAALAAEPYPE 80
Cdd:MTH00138   1 MTYLMSLFLLGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531838  81 GWGSWPVLGVMVAYLLGVGMAAVLFWGGWYEGAWVSADEFVEFSVFRGDVGGVALMYSMGGGVLVMGAWVLLLTLFVVLE 160
Cdd:MTH00138  81 SWGSWSVLGYVVGYLVGVVLAAGLFWGGWYEGSWVVVDELKEFSVLRGDVGGVALMYSSGGGMLVICAWVLLLTLFVVLE 160

                        170
                 ....*....|...
gi 403531838 161 LTRGLSRGALRAV 173
Cdd:MTH00138 161 LTRGLSRGALRAV 173
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
18-121 1.32e-08

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 50.96  E-value: 1.32e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531838   18 AVASNPSPYFAALGLVVVAGMGCGVLVGHGGSFLSLILFLIYLGGMLVVFAYSAAL-AAEPYPEGWGSWPVLGVMVAYLL 96
Cdd:pfam00499   2 GVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLlLAEEEPEKLRSGLPLAALLLGLL 81

                          90       100
                  ....*....|....*....|....*
gi 403531838   97 GVGMAAVLFWGGWYEGAWVSADEFV 121
Cdd:pfam00499  82 LLALLLLVLLSASLTPAAAAAAPDV 106
 
Name Accession Description Interval E-value
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 1-173 4.09e-84

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 177196  Cd Length: 173  Bit Score: 245.05  E-value: 4.09e-84
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531838   1 MVYIMFMFLLGLVVGLAAVASNPSPYFAALGLVVVAGMGCGVLVGHGGSFLSLILFLIYLGGMLVVFAYSAALAAEPYPE 80
Cdd:MTH00138   1 MTYLMSLFLLGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531838  81 GWGSWPVLGVMVAYLLGVGMAAVLFWGGWYEGAWVSADEFVEFSVFRGDVGGVALMYSMGGGVLVMGAWVLLLTLFVVLE 160
Cdd:MTH00138  81 SWGSWSVLGYVVGYLVGVVLAAGLFWGGWYEGSWVVVDELKEFSVLRGDVGGVALMYSSGGGMLVICAWVLLLTLFVVLE 160

                        170
                 ....*....|...
gi 403531838 161 LTRGLSRGALRAV 173
Cdd:MTH00138 161 LTRGLSRGALRAV 173
ND6 MTH00065
NADH dehydrogenase subunit 6; Provisional
 1-173 5.70e-52

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214415  Cd Length: 172  Bit Score: 163.48  E-value: 5.70e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531838   1 MVYIMFMFLLGLVVGLAAVASNPSPYFAALGLVVVAGMGCGVLVGHGGSFLSLILFLIYLGGMLVVFAYSAALAAEPYPE 80
Cdd:MTH00065   1 MMYLGFLGMLGLVVGLVAVASNPSPYFAALGLVLGAVCGCLVLVELGVSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531838  81 GWGSWPVLGVMVAYLLGVgMAAVLFWGGWYEGAWVSADEFVEFSVFRGDVGGVALMYSMGGGVLVMGAWVLLLTLFVVLE 160
Cdd:MTH00065  81 AWGSWSVLVYVLFYLLLL-IVGYILFGCNFSLEFLFTNYDTEFSVVGYDWGGVGLMYSSGGWFLMISGWVLLLTLFVVLE 159

                        170
                 ....*....|...
gi 403531838 161 LTRGLSRGALRAV 173
Cdd:MTH00065 160 VTRGLSRGSLRAV 172
ND6 MTH00115
NADH dehydrogenase subunit 6; Provisional
 1-173 1.25e-36

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214424  Cd Length: 174  Bit Score: 124.48  E-value: 1.25e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531838   1 MVYIMFMFLLGLVVGLAAVASNPSPYFAALGLVVVAGMGCGVLVGHGGSFLSLILFLIYLGGMLVVFAYSAALAAEPYPE 80
Cdd:MTH00115   1 MMYFVFLLGVCFVLGVVGVASNPSPYYGVVSLVLASVFGCGVLVSLGGSFVSLVLFLVYLGGMLVVFAYSVSLAADPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531838  81 GWGSWPVLGVMVAYLLGVGMAAVLFWGGW-YEGAWVSADEFVEFSVFRGDVGGVALMYSMGGGVLVMGAWVLLLTLFVVL 159
Cdd:MTH00115  81 AWGDWGVVGYVVGFVLVVVVVGVVVGGLWgMEGVGVVTVDSGGLFVVRLDFSGVSLFYSSGGGGLLVCGWGLLLTLFVVL 160

                        170
                 ....*....|....
gi 403531838 160 ELTRGLSRGALRAV 173
Cdd:MTH00115 161 ELVRGLSRGALRAF 174
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
 1-149 4.06e-29

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214421  Cd Length: 175  Bit Score: 105.27  E-value: 4.06e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531838   1 MVYIMFMFLLGLVVGLAAVASNPSPYFAALGLVVVAGMGCGVLVGHGGSFLSLILFLIYLGGMLVVFAYSAALAAEPYPE 80
Cdd:MTH00109   2 MMYIVFILSVLFVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYPE 81

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 403531838  81 GWGS-WPVLGVMVAYLLGVGMAAVLFWGGWYEGAWVSAD--------EFVEFSVFRGDVGGVALMYSMGGGVLVMGAW 149
Cdd:MTH00109  82 TWVSnKVVLGALLLGLLMELLLVLYVLKDDEVEVVFNFNglgdwviyDTGGSGFFSEDAMGVAALYSYGTWLVVVTGW 159
ND6 MTH00214
NADH dehydrogenase subunit 6; Provisional
 1-173 1.04e-28

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214461  Cd Length: 168  Bit Score: 104.30  E-value: 1.04e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531838   1 MVYIMFMFLLGLVVGLAAVASNPSPYFAALGLVVVAGMGCGVLVGHGGSFLSLILFLIYLGGMLVVFAYSAALAAEPYPE 80
Cdd:MTH00214   1 MLYFVFLLMFGFLLGLMMVASSPSPYFGALGLVLLALLGCFLLLSHGNSFLGLILFLIYLGGMLVVFSYSAALAADPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531838  81 GWGSWPVLGVMVAYLLGVGMAAVLFWGGWYEGAWVSADEFVEFSvfrgdVGGVALMYSMGGGVLVMGAWVLLLTLFVVLE 160
Cdd:MTH00214  81 SWGGWSVLLFFLFYLLGLGFVGFYFYGGWEMLSWMGVDEANNLD-----LSGVSDLYSRGFFLLLLGGVVLFLVLFVVLE 155

                        170
                 ....*....|...
gi 403531838 161 LTRGLSRGALRAV 173
Cdd:MTH00214 156 LVRGLSRGALRVV 168
ND6 MTH00045
NADH dehydrogenase subunit 6; Validated
 1-79 1.79e-14

NADH dehydrogenase subunit 6; Validated


Pssm-ID: 177120  Cd Length: 162  Bit Score: 66.85  E-value: 1.79e-14
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 403531838   1 MVYIMFMFLLglvVGLAAVASNPSPYFAALGLVVVAGMGCGVLVGHGGSFLSLILFLIYLGGMLVVFAYSAALAAEPYP 79
Cdd:MTH00045   2 VFYLFLILML---FGSTLVFYSLSPYYSALGLVLVSLSGCLLLSLLGLSFLALLLLLIYMGGMLVVFVYSSALSAERYP 77
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
18-121 1.32e-08

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 50.96  E-value: 1.32e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531838   18 AVASNPSPYFAALGLVVVAGMGCGVLVGHGGSFLSLILFLIYLGGMLVVFAYSAAL-AAEPYPEGWGSWPVLGVMVAYLL 96
Cdd:pfam00499   2 GVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLlLAEEEPEKLRSGLPLAALLLGLL 81

                          90       100
                  ....*....|....*....|....*
gi 403531838   97 GVGMAAVLFWGGWYEGAWVSADEFV 121
Cdd:pfam00499  82 LLALLLLVLLSASLTPAAAAAAPDV 106
ND6 MTH00152
NADH dehydrogenase subunit 6; Provisional
 1-147 2.69e-04

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214437  Cd Length: 163  Bit Score: 39.48  E-value: 2.69e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531838   1 MVYIMFMFLLGLVVGLAAVASNPSPYFAALglVVVAGMGCGVLVGHGGSFLSLILFLIYLGGMLVVFAYSAALAaePYPE 80
Cdd:MTH00152   1 MSLMILLSVCFSLFLLLPLSKQPLSLGLVL--LLLSLFVCVEIGLTLSSWYGYLLFLVYVGGLLVMFAYVVSLS--PNPL 76

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 403531838  81 GWGSWPVLGVMVAYLLGVGMaaVLFWGGWYEGAWVSADEFVEFSVFRGDVGGVALMYSMGGGVLVMG 147
Cdd:MTH00152  77 FGSNFKFVFFSLTLFGFLGL--FFFFLYLYSSGGLSLSSLFDGSSGSLSFGGGLYSSSGWSIFVFLA 141
ND6 MTH00015
NADH dehydrogenase subunit 6; Validated
 1-73 6.54e-03

NADH dehydrogenase subunit 6; Validated


Pssm-ID: 164590  Cd Length: 155  Bit Score: 35.60  E-value: 6.54e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 403531838   1 MVYIMFMFLLGLVVGLAAVASnpSPYFAALGLVVVAGMGCGVLVGHGGSFLSLILFLIYLGGMLVVFAYSAAL 73
Cdd:MTH00015   1 MSLSFFLILMISLTCSLFLAT--TPITLGINILMMALLLATTMASALSSWFAFLTFLIYVGGMLVMFAYFLAL 71
ND6 MTH00166
NADH dehydrogenase subunit 6; Provisional
 49-74 9.21e-03

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214445  Cd Length: 160  Bit Score: 35.17  E-value: 9.21e-03
                         10        20
                 ....*....|....*....|....*.
gi 403531838  49 SFLSLILFLIYLGGMLVVFAYSAALA 74
Cdd:MTH00166  46 FWFSYILFLIFLGGMLVLFIYITSLA 71
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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