|
Name |
Accession |
Description |
Interval |
E-value |
| clpC |
CHL00095 |
Clp protease ATP binding subunit |
1-830 |
0e+00 |
|
Clp protease ATP binding subunit
Pssm-ID: 214361 [Multi-domain] Cd Length: 821 Bit Score: 1454.88 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 1 MFERFTEKAIKVVMLSQEESRRLGHNFVGTEQILLGLIGENGGVAYKVLRSLGVTLREARTEVERIIGRGSGFVAVEIPF 80
Cdd:CHL00095 1 MFERFTEKAIKVIMLSQEEARRLGHNFVGTEQILLGLIGEGTGIAARALKSMGVTLKDARIEVEKIIGRGTGFVAVEIPF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 81 TPRAKRVLEIAIEEARDLGHGYIGTEHILLALLEEEVGVGVRVLQQLGLEVSQIRTEVLMQIGETLEVVLGgdrSEFFEM 160
Cdd:CHL00095 81 TPRAKRVLEMSLEEARDLGHNYIGTEHLLLALLEEGEGVAARVLENLGVDLSKIRSLILNLIGEIIEAILG---AEQSRS 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 161 SGVSIEEFTTNLTEAAFNGKLDPVVGRDEEIERVIQILARRRKNNPVLIGEPGVGKTAVAEGLAQRIVKRDVPDLLDEKQ 240
Cdd:CHL00095 158 KTPTLEEFGTNLTKEAIDGNLDPVIGREKEIERVIQILGRRTKNNPILIGEPGVGKTAIAEGLAQRIVNRDVPDILEDKL 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 241 VISLDIGLLLAGTKYRGEFEERLKRIIDEVRSSNNIILVIDEVHTLIGAGAAEGAVDAANILKPALARGELQCIGATTID 320
Cdd:CHL00095 238 VITLDIGLLLAGTKYRGEFEERLKRIFDEIQENNNIILVIDEVHTLIGAGAAEGAIDAANILKPALARGELQCIGATTLD 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 321 EYRKHIERDSALERRFQPVQIDEPSVSDTVQILRCLRPSYERHHGLKISDEALEAAASMGAQYIADRFLPDKAIDLIDEA 400
Cdd:CHL00095 318 EYRKHIEKDPALERRFQPVYVGEPSVEETIEILFGLRSRYEKHHNLSISDKALEAAAKLSDQYIADRFLPDKAIDLLDEA 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 401 GSRVRLKAVRMPDAASDLDRELRDIIKEKDTAIADQNFEVAATALDRELELRAQLSAILATVDRIPGpaiKKMVDPVVTE 480
Cdd:CHL00095 398 GSRVRLINSRLPPAARELDKELREILKDKDEAIREQDFETAKQLRDREMEVRAQIAAIIQSKKTEEE---KRLEVPVVTE 474
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 481 DDIANVVSAWTGIPVNKISKSESEKLLHMEETLHSRIIGQEQAVSAVSRAIRRARVGLRNPNRPIASFLFSGPTGVGKTE 560
Cdd:CHL00095 475 EDIAEIVSAWTGIPVNKLTKSESEKLLHMEETLHKRIIGQDEAVVAVSKAIRRARVGLKNPNRPIASFLFSGPTGVGKTE 554
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 561 LTKALALYFFGAEDAMVRLDMSEFMERHTVAKLIGSPPGYVGYSEGGQLTEAVRRKPYTVVLFDEVEKAHPDVFNLLLQI 640
Cdd:CHL00095 555 LTKALASYFFGSEDAMIRLDMSEYMEKHTVSKLIGSPPGYVGYNEGGQLTEAVRKKPYTVVLFDEIEKAHPDIFNLLLQI 634
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 641 LEDGRLTDSKGRTIDFKNTMLILTSNIGAKVIQENdssSGDIGFGGNLVNGNDSSYDRMASLVNEELKRFFRPEFLNRLD 720
Cdd:CHL00095 635 LDDGRLTDSKGRTIDFKNTLIIMTSNLGSKVIETN---SGGLGFELSENQLSEKQYKRLSNLVNEELKQFFRPEFLNRLD 711
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 721 EIIVFRQLTRNDLSQIADIMLKQLCDRAEDKSFTLKVTQRAKLVLINEGFNPTYGARPLRRAIMKLLEDRLATQLLSESI 800
Cdd:CHL00095 712 EIIVFRQLTKNDVWEIAEIMLKNLFKRLNEQGIQLEVTERIKTLLIEEGYNPLYGARPLRRAIMRLLEDPLAEEVLSFKI 791
|
810 820 830
....*....|....*....|....*....|
gi 242624367 801 EPGSMILVDSPDQKELVINISKVDIDVDQP 830
Cdd:CHL00095 792 KPGDIIIVDVNDEKEVKILLINKDNLILNK 821
|
|
| ClpA |
COG0542 |
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ... |
1-814 |
0e+00 |
|
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440308 [Multi-domain] Cd Length: 836 Bit Score: 1236.11 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 1 MFERFTEKAIKVVMLSQEESRRLGHNFVGTEQILLGLIGENGGVAYKVLRSLGVTLREARTEVERIIGRGSGF--VAVEI 78
Cdd:COG0542 2 NFEKFTEKAQEALEAAQELARRLGHQEVEPEHLLLALLEQGEGLAAKLLRKLGVDLDALREELEEALGRLPKVsgSSGQP 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 79 PFTPRAKRVLEIAIEEARDLGHGYIGTEHILLALLEEEVGVGVRVLQQLGLEVSQIRTEvlmqigetLEVVLGGDR--SE 156
Cdd:COG0542 82 YLSPRLKRVLELAELEARKLGDEYISTEHLLLALLREGEGVAARILKKLGITLEALREA--------LEELRGGSRvtSQ 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 157 FFEMSGVSIEEFTTNLTEAAFNGKLDPVVGRDEEIERVIQILARRRKNNPVLIGEPGVGKTAVAEGLAQRIVKRDVPDLL 236
Cdd:COG0542 154 NPESKTPALDKYGRDLTELAREGKLDPVIGRDEEIRRVIQILSRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGDVPESL 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 237 DEKQVISLDIGLLLAGTKYRGEFEERLKRIIDEVRSSN-NIILVIDEVHTLIGAGAAEGAVDAANILKPALARGELQCIG 315
Cdd:COG0542 234 KDKRVLSLDLGALVAGAKYRGEFEERLKAVLDEVKKSEgNIILFIDELHTLVGAGGAEGAMDAANLLKPALARGELRCIG 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 316 ATTIDEYRKHIERDSALERRFQPVQIDEPSVSDTVQILRCLRPSYERHHGLKISDEALEAAASMGAQYIADRFLPDKAID 395
Cdd:COG0542 314 ATTLDEYRKYIEKDAALERRFQPVLVEEPSVEDTISILRGLKERYEAHHGVRITDEALVAAVRLSDRYITDRFLPDKAID 393
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 396 LIDEAGSRVRLKAVRMPDAASDLDRELRDIIKEKDTAIADQN---FEVAATALDRELELRAQLSA--------------- 457
Cdd:COG0542 394 LIDEAAARVRMEIDSKPEELDELERRLEQLEIEKEALKKEQDeasFERLAELRDELAELEEELEAlkarweaekelieei 473
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 458 ------ILATVDRIPG------------PAIKKMVDPVVTEDDIANVVSAWTGIPVNKISKSESEKLLHMEETLHSRIIG 519
Cdd:COG0542 474 qelkeeLEQRYGKIPElekelaeleeelAELAPLLREEVTEEDIAEVVSRWTGIPVGKLLEGEREKLLNLEEELHERVIG 553
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 520 QEQAVSAVSRAIRRARVGLRNPNRPIASFLFSGPTGVGKTELTKALALYFFGAEDAMVRLDMSEFMERHTVAKLIGSPPG 599
Cdd:COG0542 554 QDEAVEAVADAIRRSRAGLKDPNRPIGSFLFLGPTGVGKTELAKALAEFLFGDEDALIRIDMSEYMEKHSVSRLIGAPPG 633
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 600 YVGYSEGGQLTEAVRRKPYTVVLFDEVEKAHPDVFNLLLQILEDGRLTDSKGRTIDFKNTMLILTSNIGAKVIQENdsss 679
Cdd:COG0542 634 YVGYEEGGQLTEAVRRRPYSVVLLDEIEKAHPDVFNILLQVLDDGRLTDGQGRTVDFRNTIIIMTSNIGSELILDL---- 709
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 680 gdigfggnlvNGNDSSYDRMASLVNEELKRFFRPEFLNRLDEIIVFRQLTRNDLSQIADIMLKQLCDRAEDKSFTLKVTQ 759
Cdd:COG0542 710 ----------AEDEPDYEEMKEAVMEELKKHFRPEFLNRIDEIIVFHPLSKEELRKIVDLQLKRLRKRLAERGITLELTD 779
|
810 820 830 840 850
....*....|....*....|....*....|....*....|....*....|....*
gi 242624367 760 RAKLVLINEGFNPTYGARPLRRAIMKLLEDRLATQLLSESIEPGSMILVDSPDQK 814
Cdd:COG0542 780 AAKDFLAEKGYDPEYGARPLKRAIQRELEDPLAEEILAGEIKEGDTITVDVDDGE 834
|
|
| chaperone_ClpB |
TIGR03346 |
ATP-dependent chaperone ClpB; Members of this protein family are the bacterial ATP-dependent ... |
5-812 |
0e+00 |
|
ATP-dependent chaperone ClpB; Members of this protein family are the bacterial ATP-dependent chaperone ClpB. This protein belongs to the AAA family, ATPases associated with various cellular activities (pfam00004). This molecular chaperone does not act as a protease, but rather serves to disaggregate misfolded and aggregated proteins. [Protein fate, Protein folding and stabilization]
Pssm-ID: 274529 [Multi-domain] Cd Length: 850 Bit Score: 979.83 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 5 FTEKAIKVVMLSQEESRRLGHNFVGTEQILLGLIGENGGVAYKVLRSLGVTLREARTEVERIIGR-----GSGfvaVEIP 79
Cdd:TIGR03346 1 LTEKFQEALQAAQSLALGRDHQQIEPEHLLKALLDQEGGLARPLLQKAGVNVGALRQALEKELERlpkvsGPG---GQVY 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 80 FTPRAKRVLEIAIEEARDLGHGYIGTEHILLALLEEEVGVGvRVLQQLGLEVSQIRTevlmqigeTLEVVLGGDR--SEF 157
Cdd:TIGR03346 78 LSPDLNRLLNLAEKLAQKRGDEFISSEHLLLALLDDKGTLG-KLLKEAGATADALEA--------AINAVRGGQKvtDAN 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 158 FEMSGVSIEEFTTNLTEAAFNGKLDPVVGRDEEIERVIQILARRRKNNPVLIGEPGVGKTAVAEGLAQRIVKRDVPDLLD 237
Cdd:TIGR03346 149 AEDQYEALEKYARDLTERAREGKLDPVIGRDEEIRRTIQVLSRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGDVPEGLK 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 238 EKQVISLDIGLLLAGTKYRGEFEERLKRIIDEVRSSN-NIILVIDEVHTLIGAGAAEGAVDAANILKPALARGELQCIGA 316
Cdd:TIGR03346 229 NKRLLALDMGALIAGAKYRGEFEERLKAVLNEVTKSEgQIILFIDELHTLVGAGKAEGAMDAGNMLKPALARGELHCIGA 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 317 TTIDEYRKHIERDSALERRFQPVQIDEPSVSDTVQILRCLRPSYERHHGLKISDEALEAAASMGAQYIADRFLPDKAIDL 396
Cdd:TIGR03346 309 TTLDEYRKYIEKDAALERRFQPVFVDEPSVEDTISILRGLKERYEVHHGVRITDPAIVAAATLSHRYITDRFLPDKAIDL 388
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 397 IDEAGSRVRLKAVRMPDAASDLDREL-------RDIIKEKDTA-----------IADQNFEVAA---------TALDREL 449
Cdd:TIGR03346 389 IDEAAARIRMEIDSKPEELDELDRRIiqleierEALKKEKDEAskkrledlekeLADLEEEYAEleeqwkaekASIQGIQ 468
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 450 ELRAQLSAI------------------------------LATVDRIPGPAIKKMVDPVVTEDDIANVVSAWTGIPVNKIS 499
Cdd:TIGR03346 469 QIKEEIEQVrleleqaeregdlakaaelqygklpelekqLQAAEQKLGEEQNRLLREEVTAEEIAEVVSRWTGIPVSKML 548
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 500 KSESEKLLHMEETLHSRIIGQEQAVSAVSRAIRRARVGLRNPNRPIASFLFSGPTGVGKTELTKALALYFFGAEDAMVRL 579
Cdd:TIGR03346 549 EGEREKLLHMEEELHERVVGQDEAVEAVSDAIRRSRAGLSDPNRPIGSFLFLGPTGVGKTELAKALAEFLFDSEDAMVRI 628
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 580 DMSEFMERHTVAKLIGSPPGYVGYSEGGQLTEAVRRKPYTVVLFDEVEKAHPDVFNLLLQILEDGRLTDSKGRTIDFKNT 659
Cdd:TIGR03346 629 DMSEYMEKHSVARLIGAPPGYVGYEEGGQLTEAVRRRPYSVVLFDEVEKAHPDVFNVLLQVLDDGRLTDGQGRTVDFRNT 708
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 660 MLILTSNIGAKVIQEndsssgdigfggnlvNGNDSSYDRMASLVNEELKRFFRPEFLNRLDEIIVFRQLTRNDLSQIADI 739
Cdd:TIGR03346 709 VIIMTSNLGSDFIQE---------------LAGGDDYEEMREAVMEVLRAHFRPEFLNRIDEIVVFHPLGREQIARIVEI 773
|
810 820 830 840 850 860 870
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 242624367 740 MLKQLCDRAEDKSFTLKVTQRAKLVLINEGFNPTYGARPLRRAIMKLLEDRLATQLLSESIEPGSMILVDSPD 812
Cdd:TIGR03346 774 QLGRLRKRLAERKITLELSDAALDFLAEAGYDPVYGARPLKRAIQREIENPLAKKILAGEVAPGDTIRVDVEG 846
|
|
| PRK10865 |
PRK10865 |
ATP-dependent chaperone ClpB; |
15-813 |
0e+00 |
|
ATP-dependent chaperone ClpB;
Pssm-ID: 182791 [Multi-domain] Cd Length: 857 Bit Score: 753.22 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 15 LSQEESRRLGHN--FVGTEQILLGLIGENGGVAYKVLRSLGVTLREARTEVERIIGR-----GSGFvavEIPFTPRAKRV 87
Cdd:PRK10865 14 LADAQSLALGHDnqFIEPLHLMSALLNQEGGSVRPLLTSAGINAGQLRTDINQALSRlpqveGTGG---DVQPSQDLVRV 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 88 LEIAIEEARDLGHGYIGTEHILLALLEEEvGVGVRVLQQLGLEVSQIRTEV-LMQIGETLEVVLGGDRSEffemsgvSIE 166
Cdd:PRK10865 91 LNLCDKLAQKRGDNFISSELFVLAALESR-GTLADILKAAGATTANITQAIeQMRGGESVNDQGAEDQRQ-------ALK 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 167 EFTTNLTEAAFNGKLDPVVGRDEEIERVIQILARRRKNNPVLIGEPGVGKTAVAEGLAQRIVKRDVPDLLDEKQVISLDI 246
Cdd:PRK10865 163 KYTIDLTERAEQGKLDPVIGRDEEIRRTIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIINGEVPEGLKGRRVLALDM 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 247 GLLLAGTKYRGEFEERLKRIIDEV-RSSNNIILVIDEVHTLIGAGAAEGAVDAANILKPALARGELQCIGATTIDEYRKH 325
Cdd:PRK10865 243 GALVAGAKYRGEFEERLKGVLNDLaKQEGNVILFIDELHTMVGAGKADGAMDAGNMLKPALARGELHCVGATTLDEYRQY 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 326 IERDSALERRFQPVQIDEPSVSDTVQILRCLRPSYERHHGLKISDEALEAAASMGAQYIADRFLPDKAIDLIDEAGSRVR 405
Cdd:PRK10865 323 IEKDAALERRFQKVFVAEPSVEDTIAILRGLKERYELHHHVQITDPAIVAAATLSHRYIADRQLPDKAIDLIDEAASSIR 402
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 406 LKAVRMPDAASDLDR-------ELRDIIKEKDTA---------------------------------IADQN----FEVA 441
Cdd:PRK10865 403 MQIDSKPEELDRLDRriiqlklEQQALMKESDEAskkrldmlneelsdkerqyseleeewkaekaslSGTQTikaeLEQA 482
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 442 ATALD--RELELRAQLSAI-----------LATVDRIPGPAIKkMVDPVVTEDDIANVVSAWTGIPVNKISKSESEKLLH 508
Cdd:PRK10865 483 KIAIEqaRRVGDLARMSELqygkipelekqLAAATQLEGKTMR-LLRNKVTDAEIAEVLARWTGIPVSRMLESEREKLLR 561
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 509 MEETLHSRIIGQEQAVSAVSRAIRRARVGLRNPNRPIASFLFSGPTGVGKTELTKALALYFFGAEDAMVRLDMSEFMERH 588
Cdd:PRK10865 562 MEQELHHRVIGQNEAVEAVSNAIRRSRAGLSDPNRPIGSFLFLGPTGVGKTELCKALANFMFDSDDAMVRIDMSEFMEKH 641
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 589 TVAKLIGSPPGYVGYSEGGQLTEAVRRKPYTVVLFDEVEKAHPDVFNLLLQILEDGRLTDSKGRTIDFKNTMLILTSNIG 668
Cdd:PRK10865 642 SVSRLVGAPPGYVGYEEGGYLTEAVRRRPYSVILLDEVEKAHPDVFNILLQVLDDGRLTDGQGRTVDFRNTVVIMTSNLG 721
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 669 AKVIQENdsssgdigFGgnlvngnDSSYDRMASLVNEELKRFFRPEFLNRLDEIIVFRQLTRNDLSQIADIMLKQLCDRA 748
Cdd:PRK10865 722 SDLIQER--------FG-------ELDYAHMKELVLGVVSHNFRPEFINRIDEVVVFHPLGEQHIASIAQIQLQRLYKRL 786
|
810 820 830 840 850 860
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 242624367 749 EDKSFTLKVTQRAKLVLINEGFNPTYGARPLRRAIMKLLEDRLATQLLSESIEPGSMILVDSPDQ 813
Cdd:PRK10865 787 EERGYEIHISDEALKLLSENGYDPVYGARPLKRAIQQQIENPLAQQILSGELVPGKVIRLEVNDD 851
|
|
| ClpA |
TIGR02639 |
ATP-dependent Clp protease ATP-binding subunit clpA; [Protein fate, Degradation of proteins, ... |
18-810 |
0e+00 |
|
ATP-dependent Clp protease ATP-binding subunit clpA; [Protein fate, Degradation of proteins, peptides, and glycopeptides]
Pssm-ID: 274241 [Multi-domain] Cd Length: 730 Bit Score: 749.16 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 18 EESRRLGHNFVGTEQILLGLIGENggVAYKVLRSLGVTLREARTEVERIIGRG----SGFVAVEIPFTPRAKRVLEIAIE 93
Cdd:TIGR02639 14 EEAKERRHEFVTLEHLLLALLDDN--EAIEILEECGGDVELLRKRLEDYLEENlpviPEDIDEEPEQTVGVQRVIQRALL 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 94 EARDLGHGYIGTEHILLALLEEEVGVGVRVLQQLGLEVSQIRTEVLMQIGETLEVVLGGDRSEFFEMSGVS-IEEFTTNL 172
Cdd:TIGR02639 92 HVKSAGKKEIDIGDLLVALFDEEDSHASYFLKSQGITRLDILNYISHGISKDDGKDQLGEEAGKEEEKGQDaLEKYTVDL 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 173 TEAAFNGKLDPVVGRDEEIERVIQILARRRKNNPVLIGEPGVGKTAVAEGLAQRIVKRDVPDLLDEKQVISLDIGLLLAG 252
Cdd:TIGR02639 172 TEKAKNGKIDPLIGREDELERTIQVLCRRKKNNPLLVGEPGVGKTAIVEGLALRIAEGKVPERLKNAKIYSLDMGTLLAG 251
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 253 TKYRGEFEERLKRIIDEVRSSNNIILVIDEVHTLIGAGA-AEGAVDAANILKPALARGELQCIGATTIDEYRKHIERDSA 331
Cdd:TIGR02639 252 TKYRGDFEERLKAVVSEIEKEPNAILFIDEIHTIVGAGAtSGGSMDASNLLKPALSSGKIRCIGSTTYEEYKNHFEKDRA 331
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 332 LERRFQPVQIDEPSVSDTVQILRCLRPSYERHHGLKISDEALEAAASMGAQYIADRFLPDKAIDLIDEAGSRVRLKAVRM 411
Cdd:TIGR02639 332 LSRRFQKIDVGEPSIEETVKILKGLKEQYEEFHHVKYSDEALEAAVELSARYINDRFLPDKAIDVIDEAGAAFRLRPKAK 411
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 412 PDAasdldrelrdiikekdtaiadqnfevaataldrelelraqlsailatvdripgpaikkmvdpVVTEDDIANVVSAWT 491
Cdd:TIGR02639 412 KKA--------------------------------------------------------------NVNVKDIENVVAKMA 429
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 492 GIPVNKISKSESEKLLHMEETLHSRIIGQEQAVSAVSRAIRRARVGLRNPNRPIASFLFSGPTGVGKTELTKALAlYFFG 571
Cdd:TIGR02639 430 KIPVKTVSSDDREQLKNLEKNLKAKIFGQDEAIDQLVSAIKRSRAGLGDPNKPVGSFLFVGPTGVGKTELAKQLA-EELG 508
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 572 AEdaMVRLDMSEFMERHTVAKLIGSPPGYVGYSEGGQLTEAVRRKPYTVVLFDEVEKAHPDVFNLLLQILEDGRLTDSKG 651
Cdd:TIGR02639 509 VH--LLRFDMSEYMEKHTVSRLIGSPPGYVGFEQGGLLTDAVRKHPHCVLLLDEIEKAHPDIYNILLQVMDYATLTDNNG 586
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 652 RTIDFKNTMLILTSNIGAKviqenDSSSGDIGFGGNLVNGNDssydrmaslvNEELKRFFRPEFLNRLDEIIVFRQLTRN 731
Cdd:TIGR02639 587 RKADFRNVILIMTSNAGAS-----EMSKPPIGFGGENRESKS----------LKAIKKLFSPEFRNRLDAIIHFNDLSEE 651
|
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 242624367 732 DLSQIADIMLKQLCDRAEDKSFTLKVTQRAKLVLINEGFNPTYGARPLRRAIMKLLEDRLATQLLSESIEPGSMILVDS 810
Cdd:TIGR02639 652 MAEKIVKKFLDELQDQLNEKNIELELTDDAKKYLAEKGYDEEFGARPLARVIQEEIKKPLSDEILFGKLKKGGSVKISL 730
|
|
| VI_ClpV1 |
TIGR03345 |
type VI secretion ATPase, ClpV1 family; Members of this protein family are homologs of ClpB, ... |
22-801 |
0e+00 |
|
type VI secretion ATPase, ClpV1 family; Members of this protein family are homologs of ClpB, an ATPase associated with chaperone-related functions. These ClpB homologs, designated ClpV1, are a key component of the bacterial pathogenicity-associated type VI secretion system. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis]
Pssm-ID: 274528 [Multi-domain] Cd Length: 852 Bit Score: 654.70 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 22 RLGHNFVGTEQILLGLIGENGGVAYKVLRSLGVTLREARTEVERIIGRGSgfvaVEIPFTPRAKRVLEIAIEEA-----R 96
Cdd:TIGR03345 18 ARGHPEVELEHWLLALLDQPDSDLAAILRHFGVDLGRLKADLARALDKLP----RGNTRTPVFSPHLVELLQEAwllasL 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 97 DLGHGYIGTEHILLALLEEEV--GVGVRVLQQLG-LEVSQIRTEVLMQIGETLEV-VLGGDRSEFFEMSGV----SIEEF 168
Cdd:TIGR03345 94 ELGDGRIRSGHLLLALLTDPElrRLLGSISPELAkIDREALREALPALVEGSAEAsAAAADAAPAGAAAGAagtsALDQY 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 169 TTNLTEAAFNGKLDPVVGRDEEIERVIQILARRRKNNPVLIGEPGVGKTAVAEGLAQRIVKRDVPDLLDEKQVISLDIGL 248
Cdd:TIGR03345 174 TTDLTAQAREGKIDPVLGRDDEIRQMIDILLRRRQNNPILTGEAGVGKTAVVEGLALRIAAGDVPPALRNVRLLSLDLGL 253
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 249 LLAGTKYRGEFEERLKRIIDEV-RSSNNIILVIDEVHTLIGAGAAEGAVDAANILKPALARGELQCIGATTIDEYRKHIE 327
Cdd:TIGR03345 254 LQAGASVKGEFENRLKSVIDEVkASPQPIILFIDEAHTLIGAGGQAGQGDAANLLKPALARGELRTIAATTWAEYKKYFE 333
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 328 RDSALERRFQPVQIDEPSVSDTVQILRCLRPSYERHHGLKISDEALEAAASMGAQYIADRFLPDKAIDLIDEAGSRVRLK 407
Cdd:TIGR03345 334 KDPALTRRFQVVKVEEPDEETAIRMLRGLAPVLEKHHGVLILDEAVVAAVELSHRYIPGRQLPDKAVSLLDTACARVALS 413
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 408 AVRMPDAASDLDRELRDIIKEKDTAIADQNF------------------EVAATALD----RELEL-------------- 451
Cdd:TIGR03345 414 QNATPAALEDLRRRIAALELELDALEREAALgadhderlaelraelaalEAELAALEarwqQEKELveailalraelead 493
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 452 -----------RAQLSAILATVDRIPGPaiKKMVDPVVTEDDIANVVSAWTGIPVNKISKSESEKLLHMEETLHSRIIGQ 520
Cdd:TIGR03345 494 adapaddddalRAQLAELEAALASAQGE--EPLVFPEVDAQAVAEVVADWTGIPVGRMVRDEIEAVLSLPDRLAERVIGQ 571
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 521 EQAVSAVSRAIRRARVGLRNPNRPIASFLFSGPTGVGKTELTKALALYFFGAEDAMVRLDMSEFMERHTVAKLIGSPPGY 600
Cdd:TIGR03345 572 DHALEAIAERIRTARAGLEDPRKPLGVFLLVGPSGVGKTETALALAELLYGGEQNLITINMSEFQEAHTVSRLKGSPPGY 651
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 601 VGYSEGGQLTEAVRRKPYTVVLFDEVEKAHPDVFNLLLQILEDGRLTDSKGRTIDFKNTMLILTSNIGAKVIQE--NDSS 678
Cdd:TIGR03345 652 VGYGEGGVLTEAVRRKPYSVVLLDEVEKAHPDVLELFYQVFDKGVMEDGEGREIDFKNTVILLTSNAGSDLIMAlcADPE 731
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 679 SgdigfggnlvngnDSSYDRMASLVNEELKRFFRPEFLNRLdEIIVFRQLTRNDLSQIADIMLKQLCDRAE--------- 749
Cdd:TIGR03345 732 T-------------APDPEALLEALRPELLKVFKPAFLGRM-TVIPYLPLDDDVLAAIVRLKLDRIARRLKenhgaelvy 797
|
810 820 830 840 850
....*....|....*....|....*....|....*....|....*....|..
gi 242624367 750 DKSFTLKVTQRAKLVLInegfnptyGARPLRRAIMKLLEDRLATQLLSESIE 801
Cdd:TIGR03345 798 SEALVEHIVARCTEVES--------GARNIDAILNQTLLPELSRQILERLAA 841
|
|
| clpA |
PRK11034 |
ATP-dependent Clp protease ATP-binding subunit; Provisional |
14-809 |
0e+00 |
|
ATP-dependent Clp protease ATP-binding subunit; Provisional
Pssm-ID: 236828 [Multi-domain] Cd Length: 758 Bit Score: 569.08 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 14 MLSQE----------ESRRLGHNFVGTEQILLGLIGENGgvAYKVLRSLGVTLREARTEVERIIGRGSGFVAV-----EI 78
Cdd:PRK11034 1 MLNQElelslnmafaRAREHRHEFMTVEHLLLALLSNPS--AREALEACSVDLVALRQELEAFIEQTTPVLPAseeerDT 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 79 PFTPRAKRVLEIAIEEARDLGHGYIGTEHILLALLEEEVGVGVRVLQQLglEVSQIRTEVLMQIG---ETLEVVLGGDRS 155
Cdd:PRK11034 79 QPTLSFQRVLQRAVFHVQSSGRSEVTGANVLVAIFSEQESQAAYLLRKH--EVSRLDVVNFISHGtrkDEPSQSSDPGSQ 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 156 EFFEMSGVS---IEEFTTNLTEAAFNGKLDPVVGRDEEIERVIQILARRRKNNPVLIGEPGVGKTAVAEGLAQRIVKRDV 232
Cdd:PRK11034 157 PNSEEQAGGeerMENFTTNLNQLARVGGIDPLIGREKELERAIQVLCRRRKNNPLLVGESGVGKTAIAEGLAWRIVQGDV 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 233 PDLLDEKQVISLDIGLLLAGTKYRGEFEERLKRIIDEVRSSNNIILVIDEVHTLIGAGAAEGA-VDAANILKPALARGEL 311
Cdd:PRK11034 237 PEVMADCTIYSLDIGSLLAGTKYRGDFEKRFKALLKQLEQDTNSILFIDEIHTIIGAGAASGGqVDAANLIKPLLSSGKI 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 312 QCIGATTIDEYRKHIERDSALERRFQPVQIDEPSVSDTVQILRCLRPSYERHHGLKISDEALEAAASMGAQYIADRFLPD 391
Cdd:PRK11034 317 RVIGSTTYQEFSNIFEKDRALARRFQKIDITEPSIEETVQIINGLKPKYEAHHDVRYTAKAVRAAVELAVKYINDRHLPD 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 392 KAIDLIDEAGSRVRLkavrMPdaasdldrelrdIIKEKDTaiadqnfevaataldrelelraqlsailatvdripgpaik 471
Cdd:PRK11034 397 KAIDVIDEAGARARL----MP------------VSKRKKT---------------------------------------- 420
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 472 kmvdpvVTEDDIANVVSAWTGIPVNKISKSESEKLLHMEETLHSRIIGQEQAVSAVSRAIRRARVGLRNPNRPIASFLFS 551
Cdd:PRK11034 421 ------VNVADIESVVARIARIPEKSVSQSDRDTLKNLGDRLKMLVFGQDKAIEALTEAIKMSRAGLGHEHKPVGSFLFA 494
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 552 GPTGVGKTELTKALAlYFFGAEdaMVRLDMSEFMERHTVAKLIGSPPGYVGYSEGGQLTEAVRRKPYTVVLFDEVEKAHP 631
Cdd:PRK11034 495 GPTGVGKTEVTVQLS-KALGIE--LLRFDMSEYMERHTVSRLIGAPPGYVGFDQGGLLTDAVIKHPHAVLLLDEIEKAHP 571
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 632 DVFNLLLQILEDGRLTDSKGRTIDFKNTMLILTSNIGakvIQENDSSSgdIGFggnlvNGNDSSYDRMaslvnEELKRFF 711
Cdd:PRK11034 572 DVFNLLLQVMDNGTLTDNNGRKADFRNVVLVMTTNAG---VRETERKS--IGL-----IHQDNSTDAM-----EEIKKIF 636
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 712 RPEFLNRLDEIIVFRQLTRNDLSQIADIMLKQLCDRAEDKSFTLKVTQRAKLVLINEGFNPTYGARPLRRAIMKLLEDRL 791
Cdd:PRK11034 637 TPEFRNRLDNIIWFDHLSTDVIHQVVDKFIVELQAQLDQKGVSLEVSQEARDWLAEKGYDRAMGARPMARVIQDNLKKPL 716
|
810
....*....|....*...
gi 242624367 792 ATQLLSESIEPGSMILVD 809
Cdd:PRK11034 717 ANELLFGSLVDGGQVTVA 734
|
|
| RecA-like_ClpB_Hsp104-like |
cd19499 |
Chaperone protein ClpB/Hsp104 subfamily; Bacterial Caseinolytic peptidase B (ClpB) and ... |
505-725 |
9.06e-101 |
|
Chaperone protein ClpB/Hsp104 subfamily; Bacterial Caseinolytic peptidase B (ClpB) and eukaryotic Heat shock protein 104 (Hsp104) are ATP-dependent molecular chaperones and essential proteins of the heat-shock response. ClpB/Hsp104 ATPases, in concert with the DnaK/Hsp70 chaperone system, disaggregate and reactivate aggregated proteins. This RecA-like_ClpB_Hsp104_like subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410907 [Multi-domain] Cd Length: 178 Bit Score: 309.88 E-value: 9.06e-101
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 505 KLLHMEETLHSRIIGQEQAVSAVSRAIRRARVGLRNPNRPIASFLFSGPTGVGKTELTKALALYFFGAEDAMVRLDMSEF 584
Cdd:cd19499 1 KLLNLEERLHERVVGQDEAVKAVSDAIRRARAGLSDPNRPIGSFLFLGPTGVGKTELAKALAELLFGDEDNLIRIDMSEY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 585 MERHTVAKLIGSPPGYVGYSEGGQLTEAVRRKPYTVVLFDEVEKAHPDVFNLLLQILEDGRLTDSKGRTIDFKNTMLILT 664
Cdd:cd19499 81 MEKHSVSRLIGAPPGYVGYTEGGQLTEAVRRKPYSVVLLDEIEKAHPDVQNLLLQVLDDGRLTDSHGRTVDFKNTIIIMT 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 242624367 665 SNigakviqendsssgdigfggnlvngndssydrmaslvneelkrFFRPEFLNRLDEIIVF 725
Cdd:cd19499 161 SN-------------------------------------------HFRPEFLNRIDEIVVF 178
|
|
| AAA_2 |
pfam07724 |
AAA domain (Cdc48 subfamily); This Pfam entry includes some of the AAA proteins not detected ... |
543-722 |
1.02e-85 |
|
AAA domain (Cdc48 subfamily); This Pfam entry includes some of the AAA proteins not detected by the pfam00004 model.
Pssm-ID: 400187 [Multi-domain] Cd Length: 168 Bit Score: 269.84 E-value: 1.02e-85
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 543 RPIASFLFSGPTGVGKTELTKALALYFFGAEDAMVRLDMSEFMERHTVAKLIGSPPGYVGYSEGGQLTEAVRRKPYTVVL 622
Cdd:pfam07724 1 RPIGSFLFLGPTGVGKTELAKALAELLFGDERALIRIDMSEYMEEHSVSRLIGAPPGYVGYEEGGQLTEAVRRKPYSIVL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 623 FDEVEKAHPDVFNLLLQILEDGRLTDSKGRTIDFKNTMLILTSNIGAKVIQENDSSsgdigfggnlvnGNDSSYDRMASL 702
Cdd:pfam07724 81 IDEIEKAHPGVQNDLLQILEGGTLTDKQGRTVDFKNTLFIMTGNFGSEKISDASRL------------GDSPDYELLKEE 148
|
170 180
....*....|....*....|
gi 242624367 703 VNEELKRFFRPEFLNRLDEI 722
Cdd:pfam07724 149 VMDLLKKGFIPEFLGRLPII 168
|
|
| AAA_lid_9 |
pfam17871 |
AAA lid domain; This entry represents the alpha helical AAA+ lid domain that is found to the ... |
345-442 |
4.12e-39 |
|
AAA lid domain; This entry represents the alpha helical AAA+ lid domain that is found to the C-terminus of AAA domains.
Pssm-ID: 465544 [Multi-domain] Cd Length: 104 Bit Score: 140.31 E-value: 4.12e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 345 SVSDTVQILRCLRPSYERHHGLKISDEALEAAASMGAQYIADRFLPDKAIDLIDEAGSRVRLKAVRMPDAASDLDRELRD 424
Cdd:pfam17871 1 SVEEAIEILRGLKPKYEKHHGVRISDEALEAAVKLSKRYITDRFLPDKAIDLLDEACARVRLSQESKPEELEDLERELAK 80
|
90
....*....|....*...
gi 242624367 425 IIKEKDTAIADQNFEVAA 442
Cdd:pfam17871 81 LEIEKEALEREQDFEKAE 98
|
|
| ClpB_D2-small |
pfam10431 |
C-terminal, D2-small domain, of ClpB protein; This is the C-terminal domain of ClpB protein, ... |
728-808 |
6.54e-22 |
|
C-terminal, D2-small domain, of ClpB protein; This is the C-terminal domain of ClpB protein, referred to as the D2-small domain, and is a mixed alpha-beta structure. Compared with the D1-small domain (included in AAA, pfam00004) it lacks the long coiled-coil insertion, and instead of helix C4 contains a beta-strand (e3) that is part of a three stranded beta-pleated sheet. In Thermophilus the whole protein forms a hexamer with the D1-small and D2-small domains located on the outside of the hexamer, with the long coiled-coil being exposed on the surface. The D2-small domain is essential for oligomerization, forming a tight interface with the D2-large domain of a neighbouring subunit and thereby providing enough binding energy to stabilize the functional assembly. The domain is associated with two Clp_N, pfam02861, at the N-terminus as well as AAA, pfam00004 and AAA_2, pfam07724.
Pssm-ID: 463090 [Multi-domain] Cd Length: 81 Bit Score: 90.16 E-value: 6.54e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 728 LTRNDLSQIADIMLKQLCDRAEDKSFTLKVTQRAKLVLINEGFNPTYGARPLRRAIMKLLEDRLATQLLSESIEPGSMIL 807
Cdd:pfam10431 1 LSKEELRKIVDLQLKELQKRLAERGITLELTDAAKDWLAEKGYDPEYGARPLRRAIQREIEDPLAEEILSGELKEGDTVR 80
|
.
gi 242624367 808 V 808
Cdd:pfam10431 81 V 81
|
|
| AAA |
cd00009 |
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ... |
185-337 |
3.62e-20 |
|
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.
Pssm-ID: 99707 [Multi-domain] Cd Length: 151 Bit Score: 87.97 E-value: 3.62e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 185 VGRDEEIERVIQILARRRKNNPVLIGEPGVGKTAVAEGLAQRIVKRDVPdlldekqVISLDIGLLLAGTKYRGEFEERLK 264
Cdd:cd00009 1 VGQEEAIEALREALELPPPKNLLLYGPPGTGKTTLARAIANELFRPGAP-------FLYLNASDLLEGLVVAELFGHFLV 73
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 242624367 265 RIIDE-VRSSNNIILVIDEVHTLiGAGAAEGAVDAANILKPALA-RGELQCIGATTIDEYRKHIErdsALERRFQ 337
Cdd:cd00009 74 RLLFElAEKAKPGVLFIDEIDSL-SRGAQNALLRVLETLNDLRIdRENVRVIGATNRPLLGDLDR---ALYDRLD 144
|
|
| ClpB_D2-small |
smart01086 |
C-terminal, D2-small domain, of ClpB protein; This is the C-terminal domain of ClpB protein, ... |
728-818 |
1.45e-19 |
|
C-terminal, D2-small domain, of ClpB protein; This is the C-terminal domain of ClpB protein, referred to as the D2-small domain, and is a mixed alpha-beta structure. Compared with the D1-small domain (included in AAA) it lacks the long coiled-coil insertion, and instead of helix C4 contains a beta-strand (e3) that is part of a three stranded beta-pleated sheet. In Thermophilus the whole protein forms a hexamer with the D1-small and D2-small domains located on the outside of the hexamer, with the long coiled-coil being exposed on the surface. The D2-small domain is essential for oligomerisation, forming a tight interface with the D2-large domain of a neighbouring subunit and thereby providing enough binding energy to stabilise the functional assembly. The domain is associated with two Clp_N at the N-terminus as well as AAA and AAA_2.
Pssm-ID: 198154 [Multi-domain] Cd Length: 90 Bit Score: 84.03 E-value: 1.45e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 728 LTRNDLSQIADIMLKQLCDRAEDKSFTLKVTQRAKLVLINEGFNPTYGARPLRRAIMKLLEDRLATQLLSESIEPGSMIL 807
Cdd:smart01086 1 LDKEDLVRIVDLPLNALQKRLAEKGITLEFTDEALDWLAEKGYDPKYGARPLRRIIQRELEDPLAELILSGELKDGDTVV 80
|
90
....*....|.
gi 242624367 808 VDSpDQKELVI 818
Cdd:smart01086 81 VDV-DDGELVF 90
|
|
| AAA |
cd00009 |
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ... |
518-666 |
5.92e-16 |
|
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.
Pssm-ID: 99707 [Multi-domain] Cd Length: 151 Bit Score: 75.65 E-value: 5.92e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 518 IGQEQAVSAVSRAIRRarvglrnpnRPIASFLFSGPTGVGKTELTKALALYFFGAEDAMVRLDMSEFMERHTVAKLIgsp 597
Cdd:cd00009 1 VGQEEAIEALREALEL---------PPPKNLLLYGPPGTGKTTLARAIANELFRPGAPFLYLNASDLLEGLVVAELF--- 68
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 242624367 598 pgyvGYSEGGQLTEAVRRKPYTVVLFDEVEKAHPDVFNLLLQILEDGRLTdskgrTIDFKNTMLILTSN 666
Cdd:cd00009 69 ----GHFLVRLLFELAEKAKPGVLFIDEIDSLSRGAQNALLRVLETLNDL-----RIDRENVRVIGATN 128
|
|
| Clp_N |
pfam02861 |
Clp amino terminal domain, pathogenicity island component; This short domain is found in one ... |
91-139 |
2.61e-12 |
|
Clp amino terminal domain, pathogenicity island component; This short domain is found in one or two copies at the amino terminus of ClpA and ClpB proteins from bacteria and eukaryotes. The function of these domains is uncertain but they may form a protein binding site. In many bacterial species, including E.coli, this region represents the N-terminus of one of the key components of the pathogenicity island complex that injects toxin from one bacterium into another.
Pssm-ID: 460724 [Multi-domain] Cd Length: 53 Bit Score: 62.15 E-value: 2.61e-12
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 242624367 91 AIEEARDLGHGYIGTEHILLALLEEEVGVGVRVLQQLGLEVSQIRTEVL 139
Cdd:pfam02861 1 AQELARALGHQYIGTEHLLLALLEEDDGLAARLLKKAGVDLDALREAIE 49
|
|
| Clp_N |
pfam02861 |
Clp amino terminal domain, pathogenicity island component; This short domain is found in one ... |
16-68 |
3.40e-12 |
|
Clp amino terminal domain, pathogenicity island component; This short domain is found in one or two copies at the amino terminus of ClpA and ClpB proteins from bacteria and eukaryotes. The function of these domains is uncertain but they may form a protein binding site. In many bacterial species, including E.coli, this region represents the N-terminus of one of the key components of the pathogenicity island complex that injects toxin from one bacterium into another.
Pssm-ID: 460724 [Multi-domain] Cd Length: 53 Bit Score: 61.77 E-value: 3.40e-12
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 242624367 16 SQEESRRLGHNFVGTEQILLGLIGENGGVAYKVLRSLGVTLREARTEVERIIG 68
Cdd:pfam02861 1 AQELARALGHQYIGTEHLLLALLEEDDGLAARLLKKAGVDLDALREAIEKLLG 53
|
|
| AAA |
pfam00004 |
ATPase family associated with various cellular activities (AAA); AAA family proteins often ... |
208-337 |
1.52e-11 |
|
ATPase family associated with various cellular activities (AAA); AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes.
Pssm-ID: 459627 [Multi-domain] Cd Length: 130 Bit Score: 62.23 E-value: 1.52e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 208 LIGEPGVGKTAVAEGLAQ----RIVKRDVPDLLDekqvisldiglllagtKYRGEFEERLKRIIDEVRSSNNIILVIDEV 283
Cdd:pfam00004 3 LYGPPGTGKTTLAKAVAKelgaPFIEISGSELVS----------------KYVGESEKRLRELFEAAKKLAPCVIFIDEI 66
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 242624367 284 HTLIGAGAAEG---AVDAANILKPAL-----ARGELQCIGATT-IDEYrkhierDSALERRFQ 337
Cdd:pfam00004 67 DALAGSRGSGGdseSRRVVNQLLTELdgftsSNSKVIVIAATNrPDKL------DPALLGRFD 123
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
549-672 |
3.25e-11 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 62.01 E-value: 3.25e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 549 LFSGPTGVGKTELTKALALYFFGAEDAMVRLDMSEFMERHTVAKLIGSPPGYVGYSEGGQ----LTEAVRRKPYTVVLFD 624
Cdd:smart00382 6 LIVGPPGSGKTTLARALARELGPPGGGVIYIDGEDILEEVLDQLLLIIVGGKKASGSGELrlrlALALARKLKPDVLILD 85
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 242624367 625 EVEKAHPDVFNLLLQILEDGRLTDSKGRtidFKNTMLILTSNIGAKVI 672
Cdd:smart00382 86 EITSLLDAEQEALLLLLEELRLLLLLKS---EKNLTVILTTNDEKDLG 130
|
|
| SpoVK |
COG0464 |
AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle ... |
48-354 |
3.76e-11 |
|
AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 440232 [Multi-domain] Cd Length: 397 Bit Score: 66.09 E-value: 3.76e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 48 VLRSLGVTLREARTEVERIIGRGSGFVAVEIPFTPRAKRVLEIAIEEARDLGHGYIGTEHILLALLEEEVGVGVRVLQQL 127
Cdd:COG0464 12 ALALLLLDDAALRLLLLLLLALAAALLLLLLLLLLLLLALLLVELLLLLLSGALAALLLLALLLLALLALLAALLSALEL 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 128 GLEVSQIRTEVLMQIGETLEVVLGGDRSEFFEMSGVSIEEFTTNLTEAAFNGK-----------LDPVVGRDEEIERVIQ 196
Cdd:COG0464 92 LLLGELLLLLLLLLLLLLLLLDLERALLELLRESAEALALAAPLVTYEDIGGLeeellelreaiLDDLGGLEEVKEELRE 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 197 ILARRRKNNPV-------------LIGEPGVGKTAVAEGLAQRIvkrdvpdlldEKQVISLDIGLLLAgtKYRGEFEERL 263
Cdd:COG0464 172 LVALPLKRPELreeyglppprgllLYGPPGTGKTLLARALAGEL----------GLPLIEVDLSDLVS--KYVGETEKNL 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 264 KRIIDEVRSSNNIILVIDEVHTLIGAGAAEG---AVDAANILKPALA--RGELQCIGATTideyrkHIER-DSALERRFQ 337
Cdd:COG0464 240 REVFDKARGLAPCVLFIDEADALAGKRGEVGdgvGRRVVNTLLTEMEelRSDVVVIAATN------RPDLlDPALLRRFD 313
|
330
....*....|....*...
gi 242624367 338 -PVQIDEPSVSDTVQILR 354
Cdd:COG0464 314 eIIFFPLPDAEERLEIFR 331
|
|
| AAA_5 |
pfam07728 |
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not ... |
547-666 |
1.06e-10 |
|
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not detected by the pfam00004 model.
Pssm-ID: 400191 [Multi-domain] Cd Length: 135 Bit Score: 60.00 E-value: 1.06e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 547 SFLFSGPTGVGKTELTKALALYFFGAEDAMVRldMSEFMerhTVAKLIGS--PPGYVGYSEGGQLTEAVRRKpyTVVLFD 624
Cdd:pfam07728 1 GVLLVGPPGTGKTELAERLAAALSNRPVFYVQ--LTRDT---TEEDLFGRrnIDPGGASWVDGPLVRAAREG--EIAVLD 73
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 242624367 625 EVEKAHPDVFNLLLQILEDGRLTDSKGRTID---FKNTMLILTSN 666
Cdd:pfam07728 74 EINRANPDVLNSLLSLLDERRLLLPDGGELVkaaPDGFRLIATMN 118
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
202-336 |
2.76e-08 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 53.53 E-value: 2.76e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 202 RKNNPVLIGEPGVGKTAVAEGLAQRIVKRDVPDLL-----DEKQVISLDIGLLLAGTKYRGEFEERLKRIIDEVRSSNNI 276
Cdd:smart00382 1 PGEVILIVGPPGSGKTTLARALARELGPPGGGVIYidgedILEEVLDQLLLIIVGGKKASGSGELRLRLALALARKLKPD 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 242624367 277 ILVIDEVHTLIGAG--AAEGAVDAANILKPALARGELQCIGATTideyRKHIERDSALERRF 336
Cdd:smart00382 81 VLILDEITSLLDAEqeALLLLLEELRLLLLLKSEKNLTVILTTN----DEKDLGPALLRRRF 138
|
|
| RecA-like_protease |
cd19481 |
proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of ... |
527-666 |
3.59e-08 |
|
proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410889 [Multi-domain] Cd Length: 158 Bit Score: 53.44 E-value: 3.59e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 527 VSRAIRRARVGLRNPNRPIASFLFSGPTGVGKTELTKALAlYFFGAEdaMVRLDMSEFMERhtvakligsppgYVGYSEG 606
Cdd:cd19481 8 AVEAPRRGSRLRRYGLGLPKGILLYGPPGTGKTLLAKALA-GELGLP--LIVVKLSSLLSK------------YVGESEK 72
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 242624367 607 --GQLTEAVRRKPYTVVLFDEVEKAHPD------------VFNLLLQILEDGRLTDskgrtidfkNTMLILTSN 666
Cdd:cd19481 73 nlRKIFERARRLAPCILFIDEIDAIGRKrdssgesgelrrVLNQLLTELDGVNSRS---------KVLVIAATN 137
|
|
| SpoVK |
COG0464 |
AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle ... |
361-801 |
9.45e-07 |
|
AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 440232 [Multi-domain] Cd Length: 397 Bit Score: 51.84 E-value: 9.45e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 361 ERHHGLKISDEALEAAASMGAQYIADRFLPDKAIDLIDEAGSRVRLKAVRMPDAASDLDRELRDIIKEKDTAIADQNFEV 440
Cdd:COG0464 3 ELLALAVALALALLLLDDAALRLLLLLLLALAAALLLLLLLLLLLLLALLLVELLLLLLSGALAALLLLALLLLALLALL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 441 AATALDRELELRAQLSAILATVDRIPGPAIKKMVDPVVTEDDIANVVSAWTGIPVNKISKSESEKLLHMEETLHSRIIGQ 520
Cdd:COG0464 83 AALLSALELLLLGELLLLLLLLLLLLLLLLDLERALLELLRESAEALALAAPLVTYEDIGGLEEELLELREAILDDLGGL 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 521 EQAVSAVSRAI--------RRARVGLRNPNRpiasFLFSGPTGVGKTELTKALAlYFFGAEdaMVRLDMSEFMErhtvak 592
Cdd:COG0464 163 EEVKEELRELValplkrpeLREEYGLPPPRG----LLLYGPPGTGKTLLARALA-GELGLP--LIEVDLSDLVS------ 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 593 ligsppGYVGYSEGG--QLTEAVRRKPYTVVLFDEVEKAHPD-----------VFNLLLQILEDGRltdskgrtidfKNT 659
Cdd:COG0464 230 ------KYVGETEKNlrEVFDKARGLAPCVLFIDEADALAGKrgevgdgvgrrVVNTLLTEMEELR-----------SDV 292
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 660 MLILTSNigakviqendsssgdigfggnlvngndssydrMASLVNEELKRffrpeflnRLDEIIVFRQLTRNDLSQIADI 739
Cdd:COG0464 293 VVIAATN--------------------------------RPDLLDPALLR--------RFDEIIFFPLPDAEERLEIFRI 332
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 242624367 740 MLKqlcDRAEDKSFTLkvtqrAKLVLINEGFNPTYGARPLRRAIMK---LLEDRLATQLLSESIE 801
Cdd:COG0464 333 HLR---KRPLDEDVDL-----EELAEATEGLSGADIRNVVRRAALQalrLGREPVTTEDLLEALE 389
|
|
| RecA-like_protease |
cd19481 |
proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of ... |
208-286 |
7.61e-06 |
|
proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410889 [Multi-domain] Cd Length: 158 Bit Score: 46.89 E-value: 7.61e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 242624367 208 LIGEPGVGKTAVAEGLAQRIVKrdvpdlldekQVISLDIGLLLagTKYRGEFEERLKRIIDEVRSSNNIILVIDEVHTL 286
Cdd:cd19481 31 LYGPPGTGKTLLAKALAGELGL----------PLIVVKLSSLL--SKYVGESEKNLRKIFERARRLAPCILFIDEIDAI 97
|
|
| AAA_16 |
pfam13191 |
AAA ATPase domain; This family of domains contain a P-loop motif that is characteriztic of the ... |
183-232 |
1.02e-05 |
|
AAA ATPase domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily.
Pssm-ID: 433025 [Multi-domain] Cd Length: 167 Bit Score: 46.73 E-value: 1.02e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 242624367 183 PVVGRDEEIERVIQILARRRKNNP---VLIGEPGVGKTAVAEGLAQRIVKRDV 232
Cdd:pfam13191 1 RLVGREEELEQLLDALDRVRSGRPpsvLLTGEAGTGKTTLLRELLRALERDGG 53
|
|
| RPT1 |
COG1222 |
ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification, protein ... |
440-627 |
2.50e-05 |
|
ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440835 [Multi-domain] Cd Length: 326 Bit Score: 47.31 E-value: 2.50e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 440 VAATALDRELELRAQLSAILATVdriPGPAIKKMVDPVVTEDDIANVVSAWTGIPVNKISKSESEkllhmEETLHSrIIG 519
Cdd:COG1222 12 KALLALIDALQERLGVELALLLQ---PVKALELLEEAPALLLNDANLTQKRLGTPRGTAVPAESP-----DVTFDD-IGG 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 520 QEQAVSAVSRAI--------RRARVGLRNPNRpiasFLFSGPTGVGKTELTKALA----LYFFgaedamvRLDMSEFMER 587
Cdd:COG1222 83 LDEQIEEIREAVelplknpeLFRKYGIEPPKG----VLLYGPPGTGKTLLAKAVAgelgAPFI-------RVRGSELVSK 151
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 242624367 588 htvakligsppgYVGysEGGQLT----EAVRRKPYTVVLFDEVE 627
Cdd:COG1222 152 ------------YIG--EGARNVrevfELAREKAPSIIFIDEID 181
|
|
| DnaX |
COG2812 |
DNA polymerase III, gamma/tau subunits [Replication, recombination and repair]; |
515-642 |
3.51e-05 |
|
DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];
Pssm-ID: 442061 [Multi-domain] Cd Length: 340 Bit Score: 46.72 E-value: 3.51e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 515 SRIIGQEQAVSAVSRAIRRARVGlrnpnrpiASFLFSGPTGVGKTELTKALALYFF----------GAEDAMVRLDMSEF 584
Cdd:COG2812 10 DDVVGQEHVVRTLKNALASGRLA--------HAYLFTGPRGVGKTTLARILAKALNcengptgepcGECESCRAIAAGSH 81
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 242624367 585 MERHTVAkligsPPGyvgySEGG-----QLTEAVRRKPYT----VVLFDEVEKAHPDVFNLLLQILE 642
Cdd:COG2812 82 PDVIEID-----AEA----SNIGvddirELIEKVSYAPVEgrykVYIIDEAHMLTTEAFNALLKTLE 139
|
|
| DNA_pol3_delta2 |
pfam13177 |
DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required ... |
519-642 |
1.66e-04 |
|
DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required for, along with delta' subunit, the assembly of the processivity factor beta(2) onto primed DNA in the DNA polymerase III holoenzyme-catalyzed reaction. The delta subunit is also known as HolA.
Pssm-ID: 433013 [Multi-domain] Cd Length: 161 Bit Score: 42.97 E-value: 1.66e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 519 GQEQAVSAVSRAIRRarvglrnpNRPIASFLFSGPTGVGKTELTKALALYFFGAEDamvrlDMSEFMERHTVAKLI--GS 596
Cdd:pfam13177 1 GQPEAIQLLQNSLEN--------GRLSHAYLFSGPEGVGKLELALAFAKALFCEEP-----GDDLPCGQCRSCRRIesGN 67
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 242624367 597 PPGYVGYSEGGQ---------LTEAVRRKPYT----VVLFDEVEKAHPDVFNLLLQILE 642
Cdd:pfam13177 68 HPDLVIIEPEGQsikidqireLQKEFSKSPYEgkkkVYIIEDAEKMTASAANSLLKFLE 126
|
|
| COG1223 |
COG1223 |
Predicted ATPase, AAA+ superfamily [General function prediction only]; |
517-643 |
2.09e-04 |
|
Predicted ATPase, AAA+ superfamily [General function prediction only];
Pssm-ID: 440836 [Multi-domain] Cd Length: 246 Bit Score: 43.72 E-value: 2.09e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 517 IIGQEQAVSAVSRAIR-------RARVGLRNPNRpiasFLFSGPTGVGKTELTKALA----LYFFgaedaMVRLDmsefm 585
Cdd:COG1223 4 VVGQEEAKKKLKLIIKelrrrenLRKFGLWPPRK----ILFYGPPGTGKTMLAEALAgelkLPLL-----TVRLD----- 69
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 242624367 586 erhtvaKLIGSppgYVGysEGG----QLTEAVRRKPyTVVLFDEVE---------KAHPD---VFNLLLQILED 643
Cdd:COG1223 70 ------SLIGS---YLG--ETArnlrKLFDFARRAP-CVIFFDEFDaiakdrgdqNDVGEvkrVVNALLQELDG 131
|
|
| AAA |
pfam00004 |
ATPase family associated with various cellular activities (AAA); AAA family proteins often ... |
549-666 |
2.73e-04 |
|
ATPase family associated with various cellular activities (AAA); AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes.
Pssm-ID: 459627 [Multi-domain] Cd Length: 130 Bit Score: 41.42 E-value: 2.73e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 549 LFSGPTGVGKTELTKALALYfFGAEdaMVRLDMSEFMErhtvakligsppGYVGYSEGG--QLTEAVRRKPYTVVLFDEV 626
Cdd:pfam00004 2 LLYGPPGTGKTTLAKAVAKE-LGAP--FIEISGSELVS------------KYVGESEKRlrELFEAAKKLAPCVIFIDEI 66
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 242624367 627 EKAHP-----------DVFNLLLQILEdgrltdskGRTIDFKNTMLILTSN 666
Cdd:pfam00004 67 DALAGsrgsggdsesrRVVNQLLTELD--------GFTSSNSKVIVIAATN 109
|
|
| AAA_22 |
pfam13401 |
AAA domain; |
199-286 |
4.35e-04 |
|
AAA domain;
Pssm-ID: 379165 [Multi-domain] Cd Length: 129 Bit Score: 41.17 E-value: 4.35e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 199 ARRRKNNPVLIGEPGVGKTAVAEGLAQRIVKRDVP----DLLDEKQVISLDIGLLLA---GTKYRGEFEERLKRIIDEVR 271
Cdd:pfam13401 1 IRFGAGILVLTGESGTGKTTLLRRLLEQLPEVRDSvvfvDLPSGTSPKDLLRALLRAlglPLSGRLSKEELLAALQQLLL 80
|
90
....*....|....*.
gi 242624367 272 SSNN-IILVIDEVHTL 286
Cdd:pfam13401 81 ALAVaVVLIIDEAQHL 96
|
|
| MoxR |
COG0714 |
MoxR-like ATPase [General function prediction only]; MoxR-like ATPase is part of the Pathway ... |
184-225 |
4.76e-04 |
|
MoxR-like ATPase [General function prediction only]; MoxR-like ATPase is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis
Pssm-ID: 440478 [Multi-domain] Cd Length: 292 Bit Score: 42.85 E-value: 4.76e-04
10 20 30 40
....*....|....*....|....*....|....*....|....
gi 242624367 184 VVGRDEEIERV-IQILARRrknnPVLI-GEPGVGKTAVAEGLAQ 225
Cdd:COG0714 14 YVGQEELIELVlIALLAGG----HLLLeGVPGVGKTTLAKALAR 53
|
|
| CDC6 |
COG1474 |
Cdc6-related protein, AAA superfamily ATPase [Replication, recombination and repair]; |
184-427 |
5.76e-04 |
|
Cdc6-related protein, AAA superfamily ATPase [Replication, recombination and repair];
Pssm-ID: 441083 [Multi-domain] Cd Length: 389 Bit Score: 43.30 E-value: 5.76e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 184 VVGRDEEIERVIQILA----RRRKNNPVLIGEPGVGKTAVAEGLAQRIVKRDVPDLLD-------------EKQVIS--- 243
Cdd:COG1474 28 LPHREEEIEELASALRpalrGERPSNVLIYGPTGTGKTAVAKYVLEELEEEAEERGVDvrvvyvncrqastRYRVLSril 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 244 --LDIGLLLAGTKY-RGEFEERLKRIIDEVRSSnnIILVIDEVHTLIGAGA---------AEGAVDAANIlkpALargel 311
Cdd:COG1474 108 eeLGSGEDIPSTGLsTDELFDRLYEALDERDGV--LVVVLDEIDYLVDDEGddllyqllrANEELEGARV---GV----- 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 312 qcIGATTIDEYRKHIerDSALERRFQPVQIDEP--SVSDTVQILRclrpsYERHHGLK---ISDEALEAAASMGAQYIAD 386
Cdd:COG1474 178 --IGISNDLEFLENL--DPRVKSSLGEEEIVFPpyDADELRDILE-----DRAELAFYdgvLSDEVIPLIAALAAQEHGD 248
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|
gi 242624367 387 -RflpdKAIDLIDEAG--------SRVRLKAVRMPDAASDLDReLRDIIK 427
Cdd:COG1474 249 aR----KAIDLLRVAGeiaeregsDRVTEEHVREAREKIERDR-LLEVLR 293
|
|
| AAA_22 |
pfam13401 |
AAA domain; |
549-645 |
7.90e-04 |
|
AAA domain;
Pssm-ID: 379165 [Multi-domain] Cd Length: 129 Bit Score: 40.40 E-value: 7.90e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 549 LFSGPTGVGKTELTKALALYFFGAEDAMVRLDMSEFME----RHTVAKLIGSPPGYVGYSEG--GQLTEAV-RRKPYTVV 621
Cdd:pfam13401 9 VLTGESGTGKTTLLRRLLEQLPEVRDSVVFVDLPSGTSpkdlLRALLRALGLPLSGRLSKEEllAALQQLLlALAVAVVL 88
|
90 100
....*....|....*....|....
gi 242624367 622 LFDEVEKAHPDVFNLLLQILEDGR 645
Cdd:pfam13401 89 IIDEAQHLSLEALEELRDLLNLSS 112
|
|
| MoxR |
COG0714 |
MoxR-like ATPase [General function prediction only]; MoxR-like ATPase is part of the Pathway ... |
510-666 |
9.59e-04 |
|
MoxR-like ATPase [General function prediction only]; MoxR-like ATPase is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis
Pssm-ID: 440478 [Multi-domain] Cd Length: 292 Bit Score: 42.08 E-value: 9.59e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 510 EETLHSRIIGQEqavsavsRAIRRARVGLRNpNRPIasfLFSGPTGVGKTELTKALAlyffgaedAMVRLDMS--EFMER 587
Cdd:COG0714 7 RAEIGKVYVGQE-------ELIELVLIALLA-GGHL---LLEGVPGVGKTTLAKALA--------RALGLPFIriQFTPD 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 588 HTVAKLIGSppgyvgyseggQLTEAVRRKPY--------TVVLFDEVEKAHPDVFNLLLQILEDGRLTdSKGRTIDFKNT 659
Cdd:COG0714 68 LLPSDILGT-----------YIYDQQTGEFEfrpgplfaNVLLADEINRAPPKTQSALLEAMEERQVT-IPGGTYKLPEP 135
|
....*...
gi 242624367 660 -MLILTSN 666
Cdd:COG0714 136 fLVIATQN 143
|
|
| COG3899 |
COG3899 |
Predicted ATPase [General function prediction only]; |
48-232 |
1.93e-03 |
|
Predicted ATPase [General function prediction only];
Pssm-ID: 443106 [Multi-domain] Cd Length: 1244 Bit Score: 42.15 E-value: 1.93e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 48 VLRSLGVTLREARTEVERIIGRGSGFVAVEIPFTPRAKRVLEIAIEEARDLGHGYIGTEHILLALLEEEVGVGVRVLqqL 127
Cdd:COG3899 158 LAAAAAAAAAAAAARAARLRRARAARLAALALRALLLLVLLLLLLLLLLGLLLAAAAALAAAAAAAAAAAPAAPVVL--V 235
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 128 GLEVSQIRTEVLMQIGETLEVVLGGDRSEFFEMSGVSIEEFTTNLTEAAFNGKLdpvVGRDEEIERVIQIL--ARRRKNN 205
Cdd:COG3899 236 AALLLALAALLALLLLAARLLGLAGAAALLLLGLLAAAAAGRRLLARRLIPQPL---VGREAELAALLAALerARAGRGE 312
|
170 180
....*....|....*....|....*...
gi 242624367 206 PVLI-GEPGVGKTAVAEGLAQRIVKRDV 232
Cdd:COG3899 313 LVLVsGEAGIGKSRLVRELARRARARGG 340
|
|
| AAA_5 |
pfam07728 |
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not ... |
207-336 |
2.51e-03 |
|
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not detected by the pfam00004 model.
Pssm-ID: 400191 [Multi-domain] Cd Length: 135 Bit Score: 38.81 E-value: 2.51e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 207 VLIGEPGVGKTAVAEGLAQRIVKRdvpdlldEKQVISLDIGLLLAGTKYRGEFEERLKRIID-----EVRSSNniILVID 281
Cdd:pfam07728 3 LLVGPPGTGKTELAERLAAALSNR-------PVFYVQLTRDTTEEDLFGRRNIDPGGASWVDgplvrAAREGE--IAVLD 73
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 282 EVHtligagaaEGAVDAANILKPAL---------ARGELQC------IGATTIDEYRKHIERDSALERRF 336
Cdd:pfam07728 74 EIN--------RANPDVLNSLLSLLderrlllpdGGELVKAapdgfrLIATMNPLDRGLNELSPALRSRF 135
|
|
| TIGR02928 |
TIGR02928 |
orc1/cdc6 family replication initiation protein; Members of this protein family are found ... |
182-290 |
2.74e-03 |
|
orc1/cdc6 family replication initiation protein; Members of this protein family are found exclusively in the archaea. This set of DNA binding proteins shows homology to the origin recognition complex subunit 1/cell division control protein 6 family in eukaryotes. Several members may be found in genome and interact with each other. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 274354 [Multi-domain] Cd Length: 365 Bit Score: 41.08 E-value: 2.74e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 182 DPVVGRDEEIERVIQIL--ARR--RKNNPVLIGEPGVGKTAVAEGLAQRIvKRDVPDLLDEKQVISLD------------ 245
Cdd:TIGR02928 15 DRIVHRDEQIEELAKALrpILRgsRPSNVFIYGKTGTGKTAVTKYVMKEL-EEAAEDRDVRVVTVYVNcqildtlyqvlv 93
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 242624367 246 -IGLLLAGTK----YRG-EFEERLKRIIDEVRSSNNIILVI-DEVHTLIGAG 290
Cdd:TIGR02928 94 eLANQLRGSGeevpTTGlSTSEVFRRLYKELNERGDSLIIVlDEIDYLVGDD 145
|
|
| HolB |
COG0470 |
DNA polymerase III, delta prime subunit [Replication, recombination and repair]; |
520-666 |
2.96e-03 |
|
DNA polymerase III, delta prime subunit [Replication, recombination and repair];
Pssm-ID: 440238 [Multi-domain] Cd Length: 289 Bit Score: 40.34 E-value: 2.96e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 520 QEQAVSAVSRAIRRARvglrNPNrpiaSFLFSGPTGVGKTELTKALALYFFGAEDAmvrlDMSEFMERHTVAKLIGSPPG 599
Cdd:COG0470 1 QEEAWEQLLAAAESGR----LPH----ALLLHGPPGIGKTTLALALARDLLCENPE----GGKACGQCHSRLMAAGNHPD 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 600 Y--VGYSEGG---------QLTEAVRRKPYT----VVLFDEVEKAHPDVFNLLLQILEDGRltdskgrtidfKNTMLILT 664
Cdd:COG0470 69 LleLNPEEKSdqigidqirELGEFLSLTPLEggrkVVIIDEADAMNEAAANALLKTLEEPP-----------KNTPFILI 137
|
..
gi 242624367 665 SN 666
Cdd:COG0470 138 AN 139
|
|
| DnaC |
COG1484 |
DNA replication protein DnaC [Replication, recombination and repair]; |
192-270 |
3.05e-03 |
|
DNA replication protein DnaC [Replication, recombination and repair];
Pssm-ID: 441093 [Multi-domain] Cd Length: 242 Bit Score: 40.15 E-value: 3.05e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 192 ERVIQILAR----RRKNNPVLIGEPGVGKTAVAEGLAQRIVKRD-------VPDLLDEkqvisldigllLAGTKYRGEFE 260
Cdd:COG1484 84 RRQILELATldfiERGENLILLGPPGTGKTHLAIALGHEACRAGyrvrfttAPDLVNE-----------LKEARADGRLE 152
|
90
....*....|....*..
gi 242624367 261 ERLKR-------IIDEV 270
Cdd:COG1484 153 RLLKRlakvdllILDEL 169
|
|
| RecA-like_HslU |
cd19498 |
ATP-dependent protease ATPase subunit HslU; HslU is a component of the ATP-dependent protease ... |
511-628 |
5.11e-03 |
|
ATP-dependent protease ATPase subunit HslU; HslU is a component of the ATP-dependent protease HslVU. In HslVU, HslU ATPase serves to unfold and translocate protein substrate, and the HslV protease degrades the unfolded proteins. This RecA-like_HslU subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410906 [Multi-domain] Cd Length: 183 Bit Score: 38.90 E-value: 5.11e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 511 ETLHSRIIGQEQAVSAVSRAIR----RARV--GLRNPNRPiASFLFSGPTGVGKTELTKALALYffgAEDAMVRLDMSEF 584
Cdd:cd19498 7 SELDKYIIGQDEAKRAVAIALRnrwrRMQLpeELRDEVTP-KNILMIGPTGVGKTEIARRLAKL---AGAPFIKVEATKF 82
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 242624367 585 MErhtvakligsppgyVGYSeGGQLTEAVRRKPYTVVLFDEVEK 628
Cdd:cd19498 83 TE--------------VGYV-GRDVESIIRDLVEGIVFIDEIDK 111
|
|
| PRK09183 |
PRK09183 |
transposase/IS protein; Provisional |
202-283 |
6.70e-03 |
|
transposase/IS protein; Provisional
Pssm-ID: 181681 Cd Length: 259 Bit Score: 39.30 E-value: 6.70e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242624367 202 RKNNPVLIGEPGVGKTAVAEGLAQRIVKRDVpdllDEKQVISLDIGLLLAGTKYRGEFEERLKRIIDEVRssnniILVID 281
Cdd:PRK09183 101 RNENIVLLGPSGVGKTHLAIALGYEAVRAGI----KVRFTTAADLLLQLSTAQRQGRYKTTLQRGVMAPR-----LLIID 171
|
..
gi 242624367 282 EV 283
Cdd:PRK09183 172 EI 173
|
|
| |
