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Conserved domains on  [gi|195952373|ref|YP_002122305|]
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NADH dehydrogenase subunit 2 (mitochondrion) [Opisthorchis felineus]

Protein Classification

NADH dehydrogenase subunit 2( domain architecture ID 10009546)

NADH dehydrogenase subunit 2 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND2 MTH00059
NADH dehydrogenase subunit 2; Provisional
 1-280 3.23e-59

NADH dehydrogenase subunit 2; Provisional


:

Pssm-ID: 177131  Cd Length: 289  Bit Score: 190.53  E-value: 3.23e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 195952373   1 MRGVFLGVFGFVCLVGFSVSLFISDNLLMFWLFLELASLSLIPFFFLDSNSGVLV---SLFSYIVVSGVSSSLIVSGLLL 77
Cdd:MTH00059   2 FRYIDVVIFSLILSLFFCLLCLVSDSLLGFWVFLELCGLSLIPCFFLSSNSNVLNfysSLLSYIVMSGLSSSLLVSGLLF 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 195952373  78 DDFVSMLVVGLLLKFGLFPFLGWVYIVLVYSNWLVVWGVSTILKSSFLFFSFFLSGGwGLMLVEVCCFLTLIFVGFFFWL 157
Cdd:MTH00059  82 SDLYFFIFFGFVVKFGLFPFMFWVYRVFSNSSWVVIWLISVVMKFPVLFFCFFLQGG-GLSLVFVDCFLTILFCGFLFWF 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 195952373 158 YTYSWVYYWSHSMISSSASFVVMSVELSPDLLMYVFLFYLLWATVVILLLSRLEDGSMLRFGSYFFLISVLVSFPGSLVI 237
Cdd:MTH00059 161 YSLNWEYVWCHISLSSSATLVVACFCLSIDLCFFLYLYYFFWSSGVIIYFSSLSDSNDLKGYYFFGFCFLLLSTPVSFPL 240

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|...
gi 195952373 238 FYKLFVCFCIYSCGLIVFLAWAFCNISEQFYLVKYLVGTSVPR 280
Cdd:MTH00059 241 FYKLSVSIGIIYSSIYVLLVWVIYSFSEQFYLFKLLVSYFVSN 283
 
Name Accession Description Interval E-value
ND2 MTH00059
NADH dehydrogenase subunit 2; Provisional
 1-280 3.23e-59

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177131  Cd Length: 289  Bit Score: 190.53  E-value: 3.23e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 195952373   1 MRGVFLGVFGFVCLVGFSVSLFISDNLLMFWLFLELASLSLIPFFFLDSNSGVLV---SLFSYIVVSGVSSSLIVSGLLL 77
Cdd:MTH00059   2 FRYIDVVIFSLILSLFFCLLCLVSDSLLGFWVFLELCGLSLIPCFFLSSNSNVLNfysSLLSYIVMSGLSSSLLVSGLLF 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 195952373  78 DDFVSMLVVGLLLKFGLFPFLGWVYIVLVYSNWLVVWGVSTILKSSFLFFSFFLSGGwGLMLVEVCCFLTLIFVGFFFWL 157
Cdd:MTH00059  82 SDLYFFIFFGFVVKFGLFPFMFWVYRVFSNSSWVVIWLISVVMKFPVLFFCFFLQGG-GLSLVFVDCFLTILFCGFLFWF 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 195952373 158 YTYSWVYYWSHSMISSSASFVVMSVELSPDLLMYVFLFYLLWATVVILLLSRLEDGSMLRFGSYFFLISVLVSFPGSLVI 237
Cdd:MTH00059 161 YSLNWEYVWCHISLSSSATLVVACFCLSIDLCFFLYLYYFFWSSGVIIYFSSLSDSNDLKGYYFFGFCFLLLSTPVSFPL 240

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|...
gi 195952373 238 FYKLFVCFCIYSCGLIVFLAWAFCNISEQFYLVKYLVGTSVPR 280
Cdd:MTH00059 241 FYKLSVSIGIIYSSIYVLLVWVIYSFSEQFYLFKLLVSYFVSN 283
 
Name Accession Description Interval E-value
ND2 MTH00059
NADH dehydrogenase subunit 2; Provisional
 1-280 3.23e-59

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177131  Cd Length: 289  Bit Score: 190.53  E-value: 3.23e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 195952373   1 MRGVFLGVFGFVCLVGFSVSLFISDNLLMFWLFLELASLSLIPFFFLDSNSGVLV---SLFSYIVVSGVSSSLIVSGLLL 77
Cdd:MTH00059   2 FRYIDVVIFSLILSLFFCLLCLVSDSLLGFWVFLELCGLSLIPCFFLSSNSNVLNfysSLLSYIVMSGLSSSLLVSGLLF 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 195952373  78 DDFVSMLVVGLLLKFGLFPFLGWVYIVLVYSNWLVVWGVSTILKSSFLFFSFFLSGGwGLMLVEVCCFLTLIFVGFFFWL 157
Cdd:MTH00059  82 SDLYFFIFFGFVVKFGLFPFMFWVYRVFSNSSWVVIWLISVVMKFPVLFFCFFLQGG-GLSLVFVDCFLTILFCGFLFWF 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 195952373 158 YTYSWVYYWSHSMISSSASFVVMSVELSPDLLMYVFLFYLLWATVVILLLSRLEDGSMLRFGSYFFLISVLVSFPGSLVI 237
Cdd:MTH00059 161 YSLNWEYVWCHISLSSSATLVVACFCLSIDLCFFLYLYYFFWSSGVIIYFSSLSDSNDLKGYYFFGFCFLLLSTPVSFPL 240

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|...
gi 195952373 238 FYKLFVCFCIYSCGLIVFLAWAFCNISEQFYLVKYLVGTSVPR 280
Cdd:MTH00059 241 FYKLSVSIGIIYSSIYVLLVWVIYSFSEQFYLFKLLVSYFVSN 283
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 8-121 9.76e-03

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 37.17  E-value: 9.76e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 195952373   8 VFGFVCLVGFSVSLFiSDNLLMFWLFLELASLSLIPFFFLDSNSGVLVSLFSYIVVSGVSSSLIVSGLLL-------DDF 80
Cdd:MTH00144   8 LFLFLMVMGTLLSLS-SSHWLGVWVGLEINLIGFLPLLVYKKKSSESESVVKYFIIQSLGSSLLIFGSLImynlsfsWFS 86

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 195952373  81 VSMLVVGLLLKFGLFPFLGWVYIVLVYSNWLVVWGVSTILK 121
Cdd:MTH00144  87 MSLLLLGLCLKLGLFPFHFWVPSVMAGLSWLSCFLLLTWQK 127
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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