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Conserved domains on  [gi|2462541520|ref|XP_054232659|]
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coiled-coil domain-containing protein 175 isoform X5 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
32-412 1.11e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 48.78  E-value: 1.11e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541520  32 IQEAEELMEK-----ERAEYLIRkqELTAQINEFEntREVKRMETYQK-KKELDKLQtkmskiketVTVSAAVLSDHNLE 105
Cdd:COG1196   174 KEEAERKLEAteenlERLEDILG--ELERQLEPLE--RQAEKAERYRElKEELKELE---------AELLLLKLRELEAE 240
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541520 106 IARLHESIRYWEQEVSELKKDLAILEAKLcfftdnkeklddisndekNEFLNKIKQLVETLHAARMEYKDLREKMKTLAR 185
Cdd:COG1196   241 LEELEAELEELEAELEELEAELAELEAEL------------------EELRLELEELELELEEAQAEEYELLAELARLEQ 302
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541520 186 QykIVLSEEEKAFLQKQKIHDENQKQltfisqkeyflsQKRVDIKNMEEGLITLQELQQATKTVYQQQIKILSANLERES 265
Cdd:COG1196   303 D--IARLEERRRELEERLEELEEELA------------ELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALL 368
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541520 266 QRcvitqwkmaclrkkhARWTAKIKAEIQAITEKIQNAEVRRIELLNETSFRQQEISGFVAQIEKLTTELKEEEKAFVNK 345
Cdd:COG1196   369 EA---------------EAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAEL 433
                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2462541520 346 EKMLMKELSKYEEifvkETQINKEKEEELVEYLPQLQVAEQEYKEKRRKLEELSNIITAQRQEEDLL 412
Cdd:COG1196   434 EEEEEEEEEALEE----AAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLL 496
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
287-554 1.28e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 45.05  E-value: 1.28e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541520  287 AKIKAEIQAITEKIQNAEVRRIELLNETSFRQQEISGFVAQIEKLTTELKEEEKAFVNKEK----------MLMKELSKY 356
Cdd:TIGR02168  680 EELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAeveqleeriaQLSKELTEL 759
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541520  357 EEIFVKETQINKEKEEELVEYLPQLQVAEQEYKEKRRKLEELSNIITAQRQEEDLLNNHIFLFTRDFSRYISNMqEDVKQ 436
Cdd:TIGR02168  760 EAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRI-AATER 838
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541520  437 ELQQLrDQESKKNKDHFETLkNLEngfyINDQKADLLLLENKKLKEYILY--LKNNIEKYREGQEALMHTSNDLSRQLIA 514
Cdd:TIGR02168  839 RLEDL-EEQIEELSEDIESL-AAE----IEELEELIEELESELEALLNERasLEEALALLRSELEELSEELRELESKRSE 912
                          250       260       270       280
                   ....*....|....*....|....*....|....*....|
gi 2462541520  515 QEAQYKDLwaefQTTVKILVDNGEETLQDINNLTDKLRER 554
Cdd:TIGR02168  913 LRRELEEL----REKLAQLELRLEGLEVRIDNLQERLSEE 948
 
Name Accession Description Interval E-value
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
32-412 1.11e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 48.78  E-value: 1.11e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541520  32 IQEAEELMEK-----ERAEYLIRkqELTAQINEFEntREVKRMETYQK-KKELDKLQtkmskiketVTVSAAVLSDHNLE 105
Cdd:COG1196   174 KEEAERKLEAteenlERLEDILG--ELERQLEPLE--RQAEKAERYRElKEELKELE---------AELLLLKLRELEAE 240
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541520 106 IARLHESIRYWEQEVSELKKDLAILEAKLcfftdnkeklddisndekNEFLNKIKQLVETLHAARMEYKDLREKMKTLAR 185
Cdd:COG1196   241 LEELEAELEELEAELEELEAELAELEAEL------------------EELRLELEELELELEEAQAEEYELLAELARLEQ 302
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541520 186 QykIVLSEEEKAFLQKQKIHDENQKQltfisqkeyflsQKRVDIKNMEEGLITLQELQQATKTVYQQQIKILSANLERES 265
Cdd:COG1196   303 D--IARLEERRRELEERLEELEEELA------------ELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALL 368
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541520 266 QRcvitqwkmaclrkkhARWTAKIKAEIQAITEKIQNAEVRRIELLNETSFRQQEISGFVAQIEKLTTELKEEEKAFVNK 345
Cdd:COG1196   369 EA---------------EAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAEL 433
                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2462541520 346 EKMLMKELSKYEEifvkETQINKEKEEELVEYLPQLQVAEQEYKEKRRKLEELSNIITAQRQEEDLL 412
Cdd:COG1196   434 EEEEEEEEEALEE----AAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLL 496
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
33-272 9.73e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 45.43  E-value: 9.73e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541520   33 QEAEELMEKERAEYLIRKQELTAQINEFENTREVKRMETYQKKKELDKLQTKMSKIKETVTVSAAVLSDHNLEIARLHES 112
Cdd:TIGR02168  245 QEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQ 324
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541520  113 IRYWEQEVSELKKDLAILEAKLCFFTDNKEKLD---DISNDEKNEFLNKIKQLVETLHAARMEYKDLREKMKTLARQYKI 189
Cdd:TIGR02168  325 LEELESKLDELAEELAELEEKLEELKEELESLEaelEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIER 404
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541520  190 VLSEEEKAFLQKQKIHDENQKQLTFISQKEYFLSQKRVDIKNME--------EGLITLQELQQATKTVYQQQIKILSANL 261
Cdd:TIGR02168  405 LEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEEleelqeelERLEEALEELREELEEAEQALDAAEREL 484
                          250
                   ....*....|.
gi 2462541520  262 ERESQRCVITQ 272
Cdd:TIGR02168  485 AQLQARLDSLE 495
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
287-554 1.28e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 45.05  E-value: 1.28e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541520  287 AKIKAEIQAITEKIQNAEVRRIELLNETSFRQQEISGFVAQIEKLTTELKEEEKAFVNKEK----------MLMKELSKY 356
Cdd:TIGR02168  680 EELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAeveqleeriaQLSKELTEL 759
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541520  357 EEIFVKETQINKEKEEELVEYLPQLQVAEQEYKEKRRKLEELSNIITAQRQEEDLLNNHIFLFTRDFSRYISNMqEDVKQ 436
Cdd:TIGR02168  760 EAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRI-AATER 838
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541520  437 ELQQLrDQESKKNKDHFETLkNLEngfyINDQKADLLLLENKKLKEYILY--LKNNIEKYREGQEALMHTSNDLSRQLIA 514
Cdd:TIGR02168  839 RLEDL-EEQIEELSEDIESL-AAE----IEELEELIEELESELEALLNERasLEEALALLRSELEELSEELRELESKRSE 912
                          250       260       270       280
                   ....*....|....*....|....*....|....*....|
gi 2462541520  515 QEAQYKDLwaefQTTVKILVDNGEETLQDINNLTDKLRER 554
Cdd:TIGR02168  913 LRRELEEL----REKLAQLELRLEGLEVRIDNLQERLSEE 948
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
278-557 2.79e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 40.69  E-value: 2.79e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541520 278 LRKKHARWTAkikAEIQAITEKIQNAEVRRIELLNETSFRQQEISGFVAQIEKLTTELKEEEKAF---VNKEKMLMKELS 354
Cdd:COG1196   222 LKELEAELLL---LKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELeeaQAEEYELLAELA 298
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541520 355 KYEEIFVKETQINKEKEEELVEYLPQLQVAEQEYKEKRRKLEELSNIITAQRQEEDLLNNHIFLFTRDFSRYISNMQEDV 434
Cdd:COG1196   299 RLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAE 378
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541520 435 kQELQQLRDQESKKNKDHFETLKNLENgfyINDQKADLLLLENKklkeyilyLKNNIEKYREGQEALMHTSNDLSRQLIA 514
Cdd:COG1196   379 -EELEELAEELLEALRAAAELAAQLEE---LEEAEEALLERLER--------LEEELEELEEALAELEEEEEEEEEALEE 446
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|...
gi 2462541520 515 QEAQYKDLWAEFQTTVKILVDNGEETLQDINNLTDKLRERDEK 557
Cdd:COG1196   447 AAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEA 489
PTZ00121 PTZ00121
MAEBL; Provisional
3-450 3.35e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 40.89  E-value: 3.35e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541520    3 KKATTTVYINETYTKINLKREDIALQKKciqeAEElmEKERAEYLIRKQELTAQINEFENTRE---VKRMETYQKKKELD 79
Cdd:PTZ00121  1296 KKAEEKKKADEAKKKAEEAKKADEAKKK----AEE--AKKKADAAKKKAEEAKKAAEAAKAEAeaaADEAEAAEEKAEAA 1369
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541520   80 KLQTKMSKIKETVTVSAAVLSDHNLEIARLHESIRyweQEVSELKKDLAileaklcfftdNKEKLDDISndEKNEFLNKI 159
Cdd:PTZ00121  1370 EKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDK---KKADELKKAAA-----------AKKKADEAK--KKAEEKKKA 1433
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541520  160 KQLVETLHAARmEYKDLREKMKTLARQYKIVLSEEEKAFLQKQKIHDENQKQLTFISQKEYFLSQKRVDIKNMEEGLITL 239
Cdd:PTZ00121  1434 DEAKKKAEEAK-KADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKA 1512
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541520  240 QELQQATKTVYQQQIKILSANLERESQRCVITQWKMACLRKKHarwtakikaEIQAITEKIQNAEVRRIELLNETSFRQQ 319
Cdd:PTZ00121  1513 DEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAE---------ELKKAEEKKKAEEAKKAEEDKNMALRKA 1583
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541520  320 EIsgfVAQIEKltTELKEEEKAFVNKEKMLMKELSKYEEIFVKETQINKEKEE-ELVEYLPQLQVAEQEYKEKRRKLEEL 398
Cdd:PTZ00121  1584 EE---AKKAEE--ARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEkKKVEQLKKKEAEEKKKAEELKKAEEE 1658
                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 2462541520  399 SNIITAQ---RQEEDllnnhiflftRDFSRYISNMQEDVKQELQQLRDQESKKNK 450
Cdd:PTZ00121  1659 NKIKAAEeakKAEED----------KKKAEEAKKAEEDEKKAAEALKKEAEEAKK 1703
 
Name Accession Description Interval E-value
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
32-412 1.11e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 48.78  E-value: 1.11e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541520  32 IQEAEELMEK-----ERAEYLIRkqELTAQINEFEntREVKRMETYQK-KKELDKLQtkmskiketVTVSAAVLSDHNLE 105
Cdd:COG1196   174 KEEAERKLEAteenlERLEDILG--ELERQLEPLE--RQAEKAERYRElKEELKELE---------AELLLLKLRELEAE 240
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541520 106 IARLHESIRYWEQEVSELKKDLAILEAKLcfftdnkeklddisndekNEFLNKIKQLVETLHAARMEYKDLREKMKTLAR 185
Cdd:COG1196   241 LEELEAELEELEAELEELEAELAELEAEL------------------EELRLELEELELELEEAQAEEYELLAELARLEQ 302
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541520 186 QykIVLSEEEKAFLQKQKIHDENQKQltfisqkeyflsQKRVDIKNMEEGLITLQELQQATKTVYQQQIKILSANLERES 265
Cdd:COG1196   303 D--IARLEERRRELEERLEELEEELA------------ELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALL 368
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541520 266 QRcvitqwkmaclrkkhARWTAKIKAEIQAITEKIQNAEVRRIELLNETSFRQQEISGFVAQIEKLTTELKEEEKAFVNK 345
Cdd:COG1196   369 EA---------------EAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAEL 433
                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2462541520 346 EKMLMKELSKYEEifvkETQINKEKEEELVEYLPQLQVAEQEYKEKRRKLEELSNIITAQRQEEDLL 412
Cdd:COG1196   434 EEEEEEEEEALEE----AAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLL 496
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
17-267 8.25e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 45.70  E-value: 8.25e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541520  17 KINLKREDIALQKKCIQEAEELMEKERAEylirKQELTAQINEFENTREVKRMETYQKKKELDKLQTKMSKIKETVTVSA 96
Cdd:COG1196   233 KLRELEAELEELEAELEELEAELEELEAE----LAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLE 308
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541520  97 AVLSDHNLEIARLHESIRYWEQEVSELKKDLAILEAKLcfftDNKEKLDDISNDEKNEFLNKIKQLVETLHAARMEYKDL 176
Cdd:COG1196   309 ERRRELEERLEELEEELAELEEELEELEEELEELEEEL----EEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEEL 384
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541520 177 REKMKTLARQykiVLSEEEKAFLQKQKIHDENQKQLTFISQKEYFLSQKRVDIKNMEEGLITLQELQQATKTVYQQQIKI 256
Cdd:COG1196   385 AEELLEALRA---AAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEAL 461
                         250
                  ....*....|.
gi 2462541520 257 LSANLERESQR 267
Cdd:COG1196   462 LELLAELLEEA 472
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
33-272 9.73e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 45.43  E-value: 9.73e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541520   33 QEAEELMEKERAEYLIRKQELTAQINEFENTREVKRMETYQKKKELDKLQTKMSKIKETVTVSAAVLSDHNLEIARLHES 112
Cdd:TIGR02168  245 QEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQ 324
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541520  113 IRYWEQEVSELKKDLAILEAKLCFFTDNKEKLD---DISNDEKNEFLNKIKQLVETLHAARMEYKDLREKMKTLARQYKI 189
Cdd:TIGR02168  325 LEELESKLDELAEELAELEEKLEELKEELESLEaelEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIER 404
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541520  190 VLSEEEKAFLQKQKIHDENQKQLTFISQKEYFLSQKRVDIKNME--------EGLITLQELQQATKTVYQQQIKILSANL 261
Cdd:TIGR02168  405 LEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEEleelqeelERLEEALEELREELEEAEQALDAAEREL 484
                          250
                   ....*....|.
gi 2462541520  262 ERESQRCVITQ 272
Cdd:TIGR02168  485 AQLQARLDSLE 495
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
130-408 1.06e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 45.44  E-value: 1.06e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541520  130 LEAKLCFFTDNKEKLDDISNDEKNEfLNKIKQLVetlHAARMEYKDLREKMKTLARQYKIVLSEEEKaflqkqkihdeNQ 209
Cdd:TIGR02169  672 EPAELQRLRERLEGLKRELSSLQSE-LRRIENRL---DELSQELSDASRKIGEIEKEIEQLEQEEEK-----------LK 736
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541520  210 KQLTFISQKEYFLSQKRVDIKNMEEGLITLQELQQATKTVYQQQIKILSANLEREsqRCVITQWKMACLRKKHARWTAKI 289
Cdd:TIGR02169  737 ERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHS--RIPEIQAELSKLEEEVSRIEARL 814
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541520  290 KA----------EIQAITEKIQNAEVRRIELLNETSFRQQEISGFVAQIEKLTTELKEEEKAfvnkEKMLMKELSKYeei 359
Cdd:TIGR02169  815 REieqklnrltlEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAA----LRDLESRLGDL--- 887
                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*....
gi 2462541520  360 fvketqinKEKEEELVEYLPQLQVAEQEYKEKRRKLEELSNIITAQRQE 408
Cdd:TIGR02169  888 --------KKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEA 928
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
287-554 1.28e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 45.05  E-value: 1.28e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541520  287 AKIKAEIQAITEKIQNAEVRRIELLNETSFRQQEISGFVAQIEKLTTELKEEEKAFVNKEK----------MLMKELSKY 356
Cdd:TIGR02168  680 EELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAeveqleeriaQLSKELTEL 759
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541520  357 EEIFVKETQINKEKEEELVEYLPQLQVAEQEYKEKRRKLEELSNIITAQRQEEDLLNNHIFLFTRDFSRYISNMqEDVKQ 436
Cdd:TIGR02168  760 EAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRI-AATER 838
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541520  437 ELQQLrDQESKKNKDHFETLkNLEngfyINDQKADLLLLENKKLKEYILY--LKNNIEKYREGQEALMHTSNDLSRQLIA 514
Cdd:TIGR02168  839 RLEDL-EEQIEELSEDIESL-AAE----IEELEELIEELESELEALLNERasLEEALALLRSELEELSEELRELESKRSE 912
                          250       260       270       280
                   ....*....|....*....|....*....|....*....|
gi 2462541520  515 QEAQYKDLwaefQTTVKILVDNGEETLQDINNLTDKLRER 554
Cdd:TIGR02168  913 LRRELEEL----REKLAQLELRLEGLEVRIDNLQERLSEE 948
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
11-234 1.55e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 45.06  E-value: 1.55e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541520   11 INETYTKINLKREDIALQKKCIQEAEELMEKERAEYLIRKQELTAQINEFEntREVKRMETYQKKKELDKLQTKMSKIKE 90
Cdd:TIGR02169  728 LEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLE--EALNDLEARLSHSRIPEIQAELSKLEE 805
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541520   91 TVTVSAAVLSDHNLEIARLHESIRYWEQEVSELKKDLAILEAKLcffTDNKEKLDDIsNDEKNEFLNKIKQLVETLHAAR 170
Cdd:TIGR02169  806 EVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQI---KSIEKEIENL-NGKKEELEEELEELEAALRDLE 881
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2462541520  171 MEYKDLREKMKTLARQYKIVLSEEEKAFLQKQKIHDENQKQLTFISQKEYFLSQKRVDIKNMEE 234
Cdd:TIGR02169  882 SRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEE 945
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
52-440 1.81e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 44.66  E-value: 1.81e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541520   52 ELTAQINEFEntREVKRMETYQ-KKKELDKLQtkmskiketVTVSAAVLSDHNLEIARLHESIRYWEQEVSELKKDLAIL 130
Cdd:TIGR02168  197 ELERQLKSLE--RQAEKAERYKeLKAELRELE---------LALLVLRLEELREELEELQEELKEAEEELEELTAELQEL 265
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541520  131 EAKLCFFTDNKEKLDDISNDEKNEFLNkikqLVETLHAARMEYKDLREKMKTLARQYKIVlsEEEKAFLQKQKIHDENQK 210
Cdd:TIGR02168  266 EEKLEELRLEVSELEEEIEELQKELYA----LANEISRLEQQKQILRERLANLERQLEEL--EAQLEELESKLDELAEEL 339
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541520  211 QltfisQKEYFLSQKRVDIKNMEEGLITLQELQQATKTvyqqQIKILSANLERESQRcvitqwkmaclrkkharwTAKIK 290
Cdd:TIGR02168  340 A-----ELEEKLEELKEELESLEAELEELEAELEELES----RLEELEEQLETLRSK------------------VAQLE 392
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541520  291 AEIQAITEKIQNAEVRriellnetsfrqqeISGFVAQIEKLTTELKEEEKAFVNKEkmlMKELSKYEEifvketqinkEK 370
Cdd:TIGR02168  393 LQIASLNNEIERLEAR--------------LERLEDRRERLQQEIEELLKKLEEAE---LKELQAELE----------EL 445
                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541520  371 EEELVEYLPQLQVAEQEYKEKRRKLEELSNIITAQRQEEDLLNNHIFLFTRDFSRYiSNMQEDVKQELQQ 440
Cdd:TIGR02168  446 EEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENL-EGFSEGVKALLKN 514
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
13-263 5.01e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 43.12  E-value: 5.01e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541520   13 ETYTKINLKREDIALQKKCIQEAEELMEKERAEYLIRKQELTAQINEFENtrevkrmETYQKKKELDKLQTKMSKIKETV 92
Cdd:TIGR02168  747 ERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKE-------ELKALREALDELRAELTLLNEEA 819
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541520   93 TVSAAVLSDHNLEIARLHESIRYWEQEVSELKKDLAILEAKLCFFTDNKEKLddisNDEKNEFLNKIKQLVETLHAARME 172
Cdd:TIGR02168  820 ANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEEL----ESELEALLNERASLEEALALLRSE 895
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541520  173 YKDLREKMKTLARQykiVLSEEEKAFLQKQKIHDENQKQLTFISQKEYFLSQKRVDIKNMEEGLITLQELQQATKTVYQQ 252
Cdd:TIGR02168  896 LEELSEELRELESK---RSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARR 972
                          250
                   ....*....|.
gi 2462541520  253 QIKILSANLER 263
Cdd:TIGR02168  973 RLKRLENKIKE 983
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
105-410 6.36e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 43.12  E-value: 6.36e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541520  105 EIARLHESIRYWEQEVSELKKDLAILEAKLCFFTDNKEKLDDISNDEKNEflnkikqlvetLHAARMEYKDLREKMKTLA 184
Cdd:TIGR02168  678 EIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQ-----------ISALRKDLARLEAEVEQLE 746
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541520  185 RQYKIVLSEEEKAFLQKQKIHDEnqkqltfisqkeyfLSQKRVDIKNMEEGLITLQELQQATKTVYQQQIKILSAnLERE 264
Cdd:TIGR02168  747 ERIAQLSKELTELEAEIEELEER--------------LEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDE-LRAE 811
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541520  265 SQRCVITQWKMACLRKKHARWTAKIKAEIQAITEKIQNAEVRRIELlnetsfrQQEISGFVAQIEKLTTELKEEEKAFVN 344
Cdd:TIGR02168  812 LTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESL-------AAEIEELEELIEELESELEALLNERAS 884
                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2462541520  345 KEKMLMKELSKYEeifvketqinkEKEEELVEYLPQLQVAEQEYKEKRRKLEELSNIITAQRQEED 410
Cdd:TIGR02168  885 LEEALALLRSELE-----------ELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRID 939
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
20-331 8.49e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 42.36  E-value: 8.49e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541520   20 LKREDIALQKKCIQEAEELMEKERAEYLIRKQELTAQINEFENTREVKRMETYQKKKELDKLQTKMSKI--KETVTVSAA 97
Cdd:TIGR02169  216 LLKEKREYEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLgeEEQLRVKEK 295
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541520   98 VLSDHNlEIARLHESIRYWEQEVSELKKDLAILEAKLCFFTDNKEKLDDISNDEKNEflnkIKQLVETLHAARMEYKDLR 177
Cdd:TIGR02169  296 IGELEA-EIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKR----RDKLTEEYAELKEELEDLR 370
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541520  178 EKMKTLARQYKIV---LSEEEKAFLQKQKIHDENQKQLTFISQKEYFLSQKRVDIKNMEEGLITLQELQQATKTVYQQQI 254
Cdd:TIGR02169  371 AELEEVDKEFAETrdeLKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEI 450
                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2462541520  255 KILSANLEResqrcviTQWKMACLRKKHARwtakIKAEIQAITEKIQNAEVRRIELLNETSFRQQEISGFVAQIEKL 331
Cdd:TIGR02169  451 KKQEWKLEQ-------LAADLSKYEQELYD----LKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVL 516
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
11-267 1.56e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 41.46  E-value: 1.56e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541520  11 INETYTKINLKREDIALQKKCIQEAEELMEKERAEYLIRKQELTAQINEFENTREVKRMETYQKKKELDKLQTKMSKIKE 90
Cdd:COG1196   237 LEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEE 316
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541520  91 TVTVSAAVLSDHNLEIARLHESIRYWEQEVSELKKDLAILEAKLcffTDNKEKLDDISNdEKNEFLNKIKQLVETLHAAR 170
Cdd:COG1196   317 RLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAEL---AEAEEALLEAEA-ELAEAEEELEELAEELLEAL 392
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541520 171 MEYKDLREKMKTLARQYKIVLSEEEKAFLQKQKIHDENQKQLTFISQKEYFLSQKRVDIKNMEEGLITLQELQQATKTVY 250
Cdd:COG1196   393 RAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEA 472
                         250
                  ....*....|....*..
gi 2462541520 251 QQQIKILSANLERESQR 267
Cdd:COG1196   473 ALLEAALAELLEELAEA 489
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
278-557 2.79e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 40.69  E-value: 2.79e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541520 278 LRKKHARWTAkikAEIQAITEKIQNAEVRRIELLNETSFRQQEISGFVAQIEKLTTELKEEEKAF---VNKEKMLMKELS 354
Cdd:COG1196   222 LKELEAELLL---LKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELeeaQAEEYELLAELA 298
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541520 355 KYEEIFVKETQINKEKEEELVEYLPQLQVAEQEYKEKRRKLEELSNIITAQRQEEDLLNNHIFLFTRDFSRYISNMQEDV 434
Cdd:COG1196   299 RLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAE 378
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541520 435 kQELQQLRDQESKKNKDHFETLKNLENgfyINDQKADLLLLENKklkeyilyLKNNIEKYREGQEALMHTSNDLSRQLIA 514
Cdd:COG1196   379 -EELEELAEELLEALRAAAELAAQLEE---LEEAEEALLERLER--------LEEELEELEEALAELEEEEEEEEEALEE 446
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|...
gi 2462541520 515 QEAQYKDLWAEFQTTVKILVDNGEETLQDINNLTDKLRERDEK 557
Cdd:COG1196   447 AAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEA 489
PTZ00121 PTZ00121
MAEBL; Provisional
3-450 3.35e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 40.89  E-value: 3.35e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541520    3 KKATTTVYINETYTKINLKREDIALQKKciqeAEElmEKERAEYLIRKQELTAQINEFENTRE---VKRMETYQKKKELD 79
Cdd:PTZ00121  1296 KKAEEKKKADEAKKKAEEAKKADEAKKK----AEE--AKKKADAAKKKAEEAKKAAEAAKAEAeaaADEAEAAEEKAEAA 1369
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541520   80 KLQTKMSKIKETVTVSAAVLSDHNLEIARLHESIRyweQEVSELKKDLAileaklcfftdNKEKLDDISndEKNEFLNKI 159
Cdd:PTZ00121  1370 EKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDK---KKADELKKAAA-----------AKKKADEAK--KKAEEKKKA 1433
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541520  160 KQLVETLHAARmEYKDLREKMKTLARQYKIVLSEEEKAFLQKQKIHDENQKQLTFISQKEYFLSQKRVDIKNMEEGLITL 239
Cdd:PTZ00121  1434 DEAKKKAEEAK-KADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKA 1512
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541520  240 QELQQATKTVYQQQIKILSANLERESQRCVITQWKMACLRKKHarwtakikaEIQAITEKIQNAEVRRIELLNETSFRQQ 319
Cdd:PTZ00121  1513 DEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAE---------ELKKAEEKKKAEEAKKAEEDKNMALRKA 1583
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541520  320 EIsgfVAQIEKltTELKEEEKAFVNKEKMLMKELSKYEEIFVKETQINKEKEE-ELVEYLPQLQVAEQEYKEKRRKLEEL 398
Cdd:PTZ00121  1584 EE---AKKAEE--ARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEkKKVEQLKKKEAEEKKKAEELKKAEEE 1658
                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 2462541520  399 SNIITAQ---RQEEDllnnhiflftRDFSRYISNMQEDVKQELQQLRDQESKKNK 450
Cdd:PTZ00121  1659 NKIKAAEeakKAEED----------KKKAEEAKKAEEDEKKAAEALKKEAEEAKK 1703
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
49-267 6.12e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 39.36  E-value: 6.12e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541520  49 RKQELTAQINEFENTREVKRMETYQKKKELDKLQTKMSKIKETVTVSAAVLSDHNLEIARLHESIRYWEQEVSELKKDLA 128
Cdd:COG4942    28 ELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELA 107
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541520 129 ILEAKLCFFTDNKEKLDDISNDEKNEFLNKIKQLVETLHAARMEYKDLREKMKTLARQYKIVLSEEEKAFLQKQKIHDEN 208
Cdd:COG4942   108 ELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEEER 187
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2462541520 209 QKQLTFISQKEYFLSQKRVDIKNMEEgliTLQELQQATKTvYQQQIKILSANLERESQR 267
Cdd:COG4942   188 AALEALKAERQKLLARLEKELAELAA---ELAELQQEAEE-LEALIARLEAEAAAAAER 242
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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