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Conserved domains on  [gi|2462526932|ref|XP_054225605|]
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ATP-binding cassette sub-family G member 4 isoform X1 [Homo sapiens]

Protein Classification

ABC transporter G family protein( domain architecture ID 1000947)

ABC transporter G (ABCG) family protein may be involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
3a01204 super family cl36780
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, ...
15-582 0e+00

The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, Other]


The actual alignment was detected with superfamily member TIGR00955:

Pssm-ID: 273361 [Multi-domain]  Cd Length: 617  Bit Score: 605.89  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  15 SGYKTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAGYRESGMKGQ--ILVNGRPRELRTFRKMSCYIMQDDMLLPHL 92
Cdd:TIGR00955  35 RPRKHLLKNVSGVAKPGELLAVMGSSGAGKTTLMNALAFRSPKGVKGSgsVLLNGMPIDAKEMRAISAYVQQDDLFIPTL 114
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  93 TVLEAMMVSANLKLSEK--QEVKKELVTEILTALGLMSCSHTRTAL------LSGGQRKRLAIALELVNNPPVMFFDEPT 164
Cdd:TIGR00955 115 TVREHLMFQAHLRMPRRvtKKEKRERVDEVLQALGLRKCANTRIGVpgrvkgLSGGERKRLAFASELLTDPPLLFCDEPT 194
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 165 SGLDSASCFQVVSLMKSLAQGGRTIICTIHQPSAKLFEMFDKLYILSQGQCIFKGVVTNLIPYLKGLGLHCPTYHNPADF 244
Cdd:TIGR00955 195 SGLDSFMAYSVVQVLKGLAQKGKTIICTIHQPSSELFELFDKIILMAEGRVAYLGSPDQAVPFFSDLGHPCPENYNPADF 274
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 245 IIEVASGEYGDLNPMlfRAVQNGLCAmAEKKSSPEKNEVPAPCPPCPPEVDPI------ESHTFATSTLTQFCILFKRTF 318
Cdd:TIGR00955 275 YVQVLAVIPGSENES--RERIEKICD-SFAVSDIGRDMLVNTNLWSGKAGGLVkdsenmEGIGYNASWWTQFYALLKRSW 351
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 319 LSILRDTVLTHLRFMSHVVIGVLIGLLYLHIGDDASKVFNNTGCLFFSMLFLMFAALMPTVLTFPLEMAVFMREHLNYWY 398
Cdd:TIGR00955 352 LSVLRDPLLLKVRLIQTMMTAILIGLIYLGQGLTQKGVQNINGALFLFLTNMTFQNVFPVINVFTAELPVFLRETRSGLY 431
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 399 SLKAYYLAKTMADVPFQVVCPVVYCSIVYWMTGQPAETSRFLLFSALATATALVAQSLGLLIGAASNSLQVATFVGPVTA 478
Cdd:TIGR00955 432 RVSAYFLAKTIAELPLFIILPALFTSITYWMIGLRSGATHFLTFLFLVTLVANVATSFGYLISCAFSSTSMALTVGPPFV 511
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 479 IPVLLFSGFFVSFKTIPTYLQWSSYLSYVRYGFEGVILTIYG-MERGDLTC--LEERCPFrEPQSILRALDVEDAKLYMD 555
Cdd:TIGR00955 512 IPFLLFGGFFINSDSIPVYFKWLSYLSWFRYGNEGLLINQWSdVDNIECTSanTTGPCPS-SGEVILETLSFRNADLYLD 590
                         570       580
                  ....*....|....*....|....*..
gi 2462526932 556 FLVLGIFFLALRLLAYLVLRYRVKSER 582
Cdd:TIGR00955 591 LIGLVILIFFFRLLAYFALRIRIRRKR 617
 
Name Accession Description Interval E-value
3a01204 TIGR00955
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, ...
15-582 0e+00

The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273361 [Multi-domain]  Cd Length: 617  Bit Score: 605.89  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  15 SGYKTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAGYRESGMKGQ--ILVNGRPRELRTFRKMSCYIMQDDMLLPHL 92
Cdd:TIGR00955  35 RPRKHLLKNVSGVAKPGELLAVMGSSGAGKTTLMNALAFRSPKGVKGSgsVLLNGMPIDAKEMRAISAYVQQDDLFIPTL 114
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  93 TVLEAMMVSANLKLSEK--QEVKKELVTEILTALGLMSCSHTRTAL------LSGGQRKRLAIALELVNNPPVMFFDEPT 164
Cdd:TIGR00955 115 TVREHLMFQAHLRMPRRvtKKEKRERVDEVLQALGLRKCANTRIGVpgrvkgLSGGERKRLAFASELLTDPPLLFCDEPT 194
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 165 SGLDSASCFQVVSLMKSLAQGGRTIICTIHQPSAKLFEMFDKLYILSQGQCIFKGVVTNLIPYLKGLGLHCPTYHNPADF 244
Cdd:TIGR00955 195 SGLDSFMAYSVVQVLKGLAQKGKTIICTIHQPSSELFELFDKIILMAEGRVAYLGSPDQAVPFFSDLGHPCPENYNPADF 274
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 245 IIEVASGEYGDLNPMlfRAVQNGLCAmAEKKSSPEKNEVPAPCPPCPPEVDPI------ESHTFATSTLTQFCILFKRTF 318
Cdd:TIGR00955 275 YVQVLAVIPGSENES--RERIEKICD-SFAVSDIGRDMLVNTNLWSGKAGGLVkdsenmEGIGYNASWWTQFYALLKRSW 351
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 319 LSILRDTVLTHLRFMSHVVIGVLIGLLYLHIGDDASKVFNNTGCLFFSMLFLMFAALMPTVLTFPLEMAVFMREHLNYWY 398
Cdd:TIGR00955 352 LSVLRDPLLLKVRLIQTMMTAILIGLIYLGQGLTQKGVQNINGALFLFLTNMTFQNVFPVINVFTAELPVFLRETRSGLY 431
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 399 SLKAYYLAKTMADVPFQVVCPVVYCSIVYWMTGQPAETSRFLLFSALATATALVAQSLGLLIGAASNSLQVATFVGPVTA 478
Cdd:TIGR00955 432 RVSAYFLAKTIAELPLFIILPALFTSITYWMIGLRSGATHFLTFLFLVTLVANVATSFGYLISCAFSSTSMALTVGPPFV 511
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 479 IPVLLFSGFFVSFKTIPTYLQWSSYLSYVRYGFEGVILTIYG-MERGDLTC--LEERCPFrEPQSILRALDVEDAKLYMD 555
Cdd:TIGR00955 512 IPFLLFGGFFINSDSIPVYFKWLSYLSWFRYGNEGLLINQWSdVDNIECTSanTTGPCPS-SGEVILETLSFRNADLYLD 590
                         570       580
                  ....*....|....*....|....*..
gi 2462526932 556 FLVLGIFFLALRLLAYLVLRYRVKSER 582
Cdd:TIGR00955 591 LIGLVILIFFFRLLAYFALRIRIRRKR 617
ABCG_EPDR cd03213
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette ...
10-219 3.59e-90

Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. Compared to other members of the ABC transporter subfamilies, the ABCG transporter family is composed of proteins that have an ATP-binding cassette domain at the N-terminus and a TM (transmembrane) domain at the C-terminus.


Pssm-ID: 213180 [Multi-domain]  Cd Length: 194  Bit Score: 275.97  E-value: 3.59e-90
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  10 KRIVASGYKTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAGYRES-GMKGQILVNGRPRELRTFRKMSCYIMQDDML 88
Cdd:cd03213    14 KSSPSKSGKQLLKNVSGKAKPGELTAIMGPSGAGKSTLLNALAGRRTGlGVSGEVLINGRPLDKRSFRKIIGYVPQDDIL 93
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  89 LPHLTVLEAMMVSANLKlsekqevkkelvteiltalGLmscshtrtallSGGQRKRLAIALELVNNPPVMFFDEPTSGLD 168
Cdd:cd03213    94 HPTLTVRETLMFAAKLR-------------------GL-----------SGGERKRVSIALELVSNPSLLFLDEPTSGLD 143
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2462526932 169 SASCFQVVSLMKSLAQGGRTIICTIHQPSAKLFEMFDKLYILSQGQCIFKG 219
Cdd:cd03213   144 SSSALQVMSLLRRLADTGRTIICSIHQPSSEIFELFDKLLLLSQGRVIYFG 194
PLN03211 PLN03211
ABC transporter G-25; Provisional
18-580 8.57e-82

ABC transporter G-25; Provisional


Pssm-ID: 215634 [Multi-domain]  Cd Length: 659  Bit Score: 269.44  E-value: 8.57e-82
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  18 KTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAG-YRESGMKGQILVNGRPRELRTFRKMScYIMQDDMLLPHLTVLE 96
Cdd:PLN03211   81 RTILNGVTGMASPGEILAVLGPSGSGKSTLLNALAGrIQGNNFTGTILANNRKPTKQILKRTG-FVTQDDILYPHLTVRE 159
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  97 AMMVSANLKL--SEKQEVKKELVTEILTALGLMSCSHTRTAL-----LSGGQRKRLAIALELVNNPPVMFFDEPTSGLDS 169
Cdd:PLN03211  160 TLVFCSLLRLpkSLTKQEKILVAESVISELGLTKCENTIIGNsfirgISGGERKRVSIAHEMLINPSLLILDEPTSGLDA 239
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 170 ASCFQVVSLMKSLAQGGRTIICTIHQPSAKLFEMFDKLYILSQGQCIFKGVVTNLIPYLKGLGLHCPTYHNPADFIIEVA 249
Cdd:PLN03211  240 TAAYRLVLTLGSLAQKGKTIVTSMHQPSSRVYQMFDSVLVLSEGRCLFFGKGSDAMAYFESVGFSPSFPMNPADFLLDLA 319
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 250 SGeYGDLNPMLFRA---VQNGLCAMAEKKSSPEKNEVPAPCPPCPPEVDPIESHTFA----------TSTLTQFCILFKR 316
Cdd:PLN03211  320 NG-VCQTDGVSEREkpnVKQSLVASYNTLLAPKVKAAIEMSHFPQANARFVGSASTKehrssdrisiSTWFNQFSILLQR 398
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 317 TfLSILRDTVLTHLRFMSHVVIGVLIGLLYLHigDDASKVFNNTGCLFFSMLFLMFAALMPTVLTFPLEMAVFMREHLNY 396
Cdd:PLN03211  399 S-LKERKHESFNTLRVFQVIAAALLAGLMWWH--SDFRDVQDRLGLLFFISIFWGVFPSFNSVFVFPQERAIFVKERASG 475
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 397 WYSLKAYYLAKTMADVPFQVVCPVVYCSIVYWMTGQPAETSRFLLFSALATATALVAQSLGLLIGAASNSLQVATFVGPV 476
Cdd:PLN03211  476 MYTLSSYFMARIVGDLPMELILPTIFLTVTYWMAGLKPELGAFLLTLLVLLGYVLVSQGLGLALGAAIMDAKKASTIVTV 555
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 477 TAIPVLLFSGFFVSfkTIPTYLQWSSYLSYVRYGFEGVILTIYGMERGDLTCLEERCPFREPQSILRALDVE---DAKLY 553
Cdd:PLN03211  556 TMLAFVLTGGFYVH--KLPSCMAWIKYISTTFYSYRLLINVQYGEGKRISSLLGCSLPHGSDRASCKFVEEDvagQISPA 633
                         570       580
                  ....*....|....*....|....*..
gi 2462526932 554 MDFLVLGIFFLALRLLAYLVLRyRVKS 580
Cdd:PLN03211  634 TSVSVLIFMFVGYRLLAYLALR-RIKH 659
ABC2_membrane pfam01061
ABC-2 type transporter;
313-515 2.42e-46

ABC-2 type transporter;


Pssm-ID: 426023 [Multi-domain]  Cd Length: 204  Bit Score: 161.67  E-value: 2.42e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 313 LFKRTFLSILRDTVLTHLRFMSHVVIGVLIGLLYLHIGDDASkVFNNTGCLFFSMLFLMFAALMPTVLTFPLEMAVFMRE 392
Cdd:pfam01061   1 LLKREFLRRWRDPSLGLWRLIQPILMALIFGTLFGNLGNQQG-GLNRPGLLFFSILFNAFSALSGISPVFEKERGVLYRE 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 393 HLNYWYSLKAYYLAKTMADVPFQVVCPVVYCSIVYWMTGQPAETSRFLLFSALATATALVAQSLGLLIGAASNSLQVATF 472
Cdd:pfam01061  80 LASPLYSPSAYVLAKILSELPLSLLQSLIFLLIVYFMVGLPPSAGRFFLFLLVLLLTALAASSLGLFISALAPSFEDASQ 159
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 2462526932 473 VGPVTAIPVLLFSGFFVSFKTIPTYLQWSSYLSYVRYGFEGVI 515
Cdd:pfam01061 160 LGPLVLLPLLLLSGFFIPIDSMPVWWQWIYYLNPLTYAIEALR 202
CcmA COG1131
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
32-225 3.94e-42

ABC-type multidrug transport system, ATPase component [Defense mechanisms];


Pssm-ID: 440746 [Multi-domain]  Cd Length: 236  Bit Score: 151.37  E-value: 3.94e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  32 ELIGIMGPSGAGKSTFMNILAGYRESGmKGQILVNGRP--RELRTFRKMSCYIMQDDMLLPHLTVLEAMMVSANLK-LSE 108
Cdd:COG1131    27 EIFGLLGPNGAGKTTTIRMLLGLLRPT-SGEVRVLGEDvaRDPAEVRRRIGYVPQEPALYPDLTVRENLRFFARLYgLPR 105
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 109 KQevKKELVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKSLAQGGRT 188
Cdd:COG1131   106 KE--ARERIDELLELFGLTDAADRKVGTLSGGMKQRLGLALALLHDPELLILDEPTSGLDPEARRELWELLRELAAEGKT 183
                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 2462526932 189 IICTIHQPSAkLFEMFDKLYILSQGQCIFKGVVTNLI 225
Cdd:COG1131   184 VLLSTHYLEE-AERLCDRVAIIDKGRIVADGTPDELK 219
AztA NF040873
zinc ABC transporter ATP-binding protein AztA;
19-196 8.51e-17

zinc ABC transporter ATP-binding protein AztA;


Pssm-ID: 468810 [Multi-domain]  Cd Length: 191  Bit Score: 78.81  E-value: 8.51e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  19 TLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAGYResgmkgqilvngRPRELRTFRKMSC---YIMQ---DDMLLPhL 92
Cdd:NF040873    6 PVLHGVDLTIPAGSLTAVVGPNGSGKSTLLKVLAGVL------------RPTSGTVRRAGGArvaYVPQrseVPDSLP-L 72
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  93 TVLEAMMVSANLKLSEKQEVKKE---LVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDS 169
Cdd:NF040873   73 TVRDLVAMGRWARRGLWRRLTRDdraAVDDALERVGLADLAGRQLGELSGGQRQRALLAQGLAQEADLLLLDEPTTGLDA 152
                         170       180
                  ....*....|....*....|....*..
gi 2462526932 170 ASCFQVVSLMKSLAQGGRTIICTIHQP 196
Cdd:NF040873  153 ESRERIIALLAEEHARGATVVVVTHDL 179
40850658_otr NF000106
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
99-239 1.38e-09

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;


Pssm-ID: 411078 [Multi-domain]  Cd Length: 351  Bit Score: 60.13  E-value: 1.38e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  99 MVSANLKLSEKQevKKELVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSL 178
Cdd:NF000106  109 MIGR*LDLSRKD--ARARADELLERFSLTEAAGRAAAKYSGGMRRRLDLAASMIGRPAVLYLDEPTTGLDPRTRNEVWDE 186
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462526932 179 MKSLAQGGRTIICTIhQPSAKLFEMFDKLYILSQGQCIFKGVVTNLIPYLKGLGLHCPTYH 239
Cdd:NF000106  187 VRSMVRDGATVLLTT-QYMEEAEQLAHELTVIDRGRVIADGKVDELKTKVGGRTLQIRPAH 246
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
30-200 8.51e-09

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 54.69  E-value: 8.51e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932   30 RRELIGIMGPSGAGKSTFMNILAGYRESGMKGQILVNGrprelrtfrkmscyimqddmllphltvleammvsanlklsek 109
Cdd:smart00382   1 PGEVILIVGPPGSGKTTLARALARELGPPGGGVIYIDG------------------------------------------ 38
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  110 qevkkELVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSAS------CFQVVSLMKSLA 183
Cdd:smart00382  39 -----EDILEEVLDQLLLIIVGGKKASGSGELRLRLALALARKLKPDVLILDEITSLLDAEQeallllLEELRLLLLLKS 113
                          170
                   ....*....|....*..
gi 2462526932  184 QGGRTIICTIHQPSAKL 200
Cdd:smart00382 114 EKNLTVILTTNDEKDLG 130
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
30-168 7.24e-06

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 48.97  E-value: 7.24e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  30 RRELIGIMGPSGAGKSTFMNILAGYRESGmKGQILVNGRP---RELRTFRK---MScyimQDDMLLPHLTVLEAMMVSAN 103
Cdd:NF033858  291 RGEIFGFLGSNGCGKSTTMKMLTGLLPAS-EGEAWLFGQPvdaGDIATRRRvgyMS----QAFSLYGELTVRQNLELHAR 365
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2462526932 104 L-KLSEKQevKKELVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLD 168
Cdd:NF033858  366 LfHLPAAE--IAARVAEMLERFDLADVADALPDSLPLGIRQRLSLAVAVIHKPELLILDEPTSGVD 429
GguA NF040905
sugar ABC transporter ATP-binding protein;
30-216 2.60e-05

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 47.09  E-value: 2.60e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  30 RRELIGIMGPSGAGKSTFMNILAGYRESG-MKGQILVNGRPRELRTFR----KMSCYIMQDDMLLPHLTVLEammvsaNL 104
Cdd:NF040905   26 EGEIHALCGENGAGKSTLMKVLSGVYPHGsYEGEILFDGEVCRFKDIRdseaLGIVIIHQELALIPYLSIAE------NI 99
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 105 KLSEKQ---------EVKKElVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGL---DSAsc 172
Cdd:NF040905  100 FLGNERakrgvidwnETNRR-ARELLAKVGLDESPDTLVTDIGVGKQQLVEIAKALSKDVKLLILDEPTAALneeDSA-- 176
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 2462526932 173 fQVVSLMKSL-AQGGRTIIctIhqpSAKLFEMF---DKLYILSQGQCI 216
Cdd:NF040905  177 -ALLDLLLELkAQGITSII--I---SHKLNEIRrvaDSITVLRDGRTI 218
GguA NF040905
sugar ABC transporter ATP-binding protein;
30-214 6.57e-05

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 45.55  E-value: 6.57e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  30 RR-ELIGIMGPSGAGKSTF-MNILA---GYRESGmkgQILVNGRPRELRTF--------------RKMSCYIMQDDML-- 88
Cdd:NF040905  284 RRgEIVGIAGLMGAGRTELaMSVFGrsyGRNISG---TVFKDGKEVDVSTVsdaidaglayvtedRKGYGLNLIDDIKrn 360
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  89 --LPHLTvleamMVSANLKLSEKQEVKkeLVTEILTALGLMSCS-HTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTS 165
Cdd:NF040905  361 itLANLG-----KVSRRGVIDENEEIK--VAEEYRKKMNIKTPSvFQKVGNLSGGNQQKVVLSKWLFTDPDVLILDEPTR 433
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2462526932 166 GLDSASCFQVVSLMKSLAQGGRTIIcTIhqpSAKLFE---MFDKLYILSQGQ 214
Cdd:NF040905  434 GIDVGAKYEIYTIINELAAEGKGVI-VI---SSELPEllgMCDRIYVMNEGR 481
 
Name Accession Description Interval E-value
3a01204 TIGR00955
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, ...
15-582 0e+00

The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273361 [Multi-domain]  Cd Length: 617  Bit Score: 605.89  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  15 SGYKTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAGYRESGMKGQ--ILVNGRPRELRTFRKMSCYIMQDDMLLPHL 92
Cdd:TIGR00955  35 RPRKHLLKNVSGVAKPGELLAVMGSSGAGKTTLMNALAFRSPKGVKGSgsVLLNGMPIDAKEMRAISAYVQQDDLFIPTL 114
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  93 TVLEAMMVSANLKLSEK--QEVKKELVTEILTALGLMSCSHTRTAL------LSGGQRKRLAIALELVNNPPVMFFDEPT 164
Cdd:TIGR00955 115 TVREHLMFQAHLRMPRRvtKKEKRERVDEVLQALGLRKCANTRIGVpgrvkgLSGGERKRLAFASELLTDPPLLFCDEPT 194
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 165 SGLDSASCFQVVSLMKSLAQGGRTIICTIHQPSAKLFEMFDKLYILSQGQCIFKGVVTNLIPYLKGLGLHCPTYHNPADF 244
Cdd:TIGR00955 195 SGLDSFMAYSVVQVLKGLAQKGKTIICTIHQPSSELFELFDKIILMAEGRVAYLGSPDQAVPFFSDLGHPCPENYNPADF 274
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 245 IIEVASGEYGDLNPMlfRAVQNGLCAmAEKKSSPEKNEVPAPCPPCPPEVDPI------ESHTFATSTLTQFCILFKRTF 318
Cdd:TIGR00955 275 YVQVLAVIPGSENES--RERIEKICD-SFAVSDIGRDMLVNTNLWSGKAGGLVkdsenmEGIGYNASWWTQFYALLKRSW 351
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 319 LSILRDTVLTHLRFMSHVVIGVLIGLLYLHIGDDASKVFNNTGCLFFSMLFLMFAALMPTVLTFPLEMAVFMREHLNYWY 398
Cdd:TIGR00955 352 LSVLRDPLLLKVRLIQTMMTAILIGLIYLGQGLTQKGVQNINGALFLFLTNMTFQNVFPVINVFTAELPVFLRETRSGLY 431
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 399 SLKAYYLAKTMADVPFQVVCPVVYCSIVYWMTGQPAETSRFLLFSALATATALVAQSLGLLIGAASNSLQVATFVGPVTA 478
Cdd:TIGR00955 432 RVSAYFLAKTIAELPLFIILPALFTSITYWMIGLRSGATHFLTFLFLVTLVANVATSFGYLISCAFSSTSMALTVGPPFV 511
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 479 IPVLLFSGFFVSFKTIPTYLQWSSYLSYVRYGFEGVILTIYG-MERGDLTC--LEERCPFrEPQSILRALDVEDAKLYMD 555
Cdd:TIGR00955 512 IPFLLFGGFFINSDSIPVYFKWLSYLSWFRYGNEGLLINQWSdVDNIECTSanTTGPCPS-SGEVILETLSFRNADLYLD 590
                         570       580
                  ....*....|....*....|....*..
gi 2462526932 556 FLVLGIFFLALRLLAYLVLRYRVKSER 582
Cdd:TIGR00955 591 LIGLVILIFFFRLLAYFALRIRIRRKR 617
ABCG_EPDR cd03213
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette ...
10-219 3.59e-90

Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. Compared to other members of the ABC transporter subfamilies, the ABCG transporter family is composed of proteins that have an ATP-binding cassette domain at the N-terminus and a TM (transmembrane) domain at the C-terminus.


Pssm-ID: 213180 [Multi-domain]  Cd Length: 194  Bit Score: 275.97  E-value: 3.59e-90
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  10 KRIVASGYKTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAGYRES-GMKGQILVNGRPRELRTFRKMSCYIMQDDML 88
Cdd:cd03213    14 KSSPSKSGKQLLKNVSGKAKPGELTAIMGPSGAGKSTLLNALAGRRTGlGVSGEVLINGRPLDKRSFRKIIGYVPQDDIL 93
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  89 LPHLTVLEAMMVSANLKlsekqevkkelvteiltalGLmscshtrtallSGGQRKRLAIALELVNNPPVMFFDEPTSGLD 168
Cdd:cd03213    94 HPTLTVRETLMFAAKLR-------------------GL-----------SGGERKRVSIALELVSNPSLLFLDEPTSGLD 143
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2462526932 169 SASCFQVVSLMKSLAQGGRTIICTIHQPSAKLFEMFDKLYILSQGQCIFKG 219
Cdd:cd03213   144 SSSALQVMSLLRRLADTGRTIICSIHQPSSEIFELFDKLLLLSQGRVIYFG 194
PLN03211 PLN03211
ABC transporter G-25; Provisional
18-580 8.57e-82

ABC transporter G-25; Provisional


Pssm-ID: 215634 [Multi-domain]  Cd Length: 659  Bit Score: 269.44  E-value: 8.57e-82
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  18 KTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAG-YRESGMKGQILVNGRPRELRTFRKMScYIMQDDMLLPHLTVLE 96
Cdd:PLN03211   81 RTILNGVTGMASPGEILAVLGPSGSGKSTLLNALAGrIQGNNFTGTILANNRKPTKQILKRTG-FVTQDDILYPHLTVRE 159
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  97 AMMVSANLKL--SEKQEVKKELVTEILTALGLMSCSHTRTAL-----LSGGQRKRLAIALELVNNPPVMFFDEPTSGLDS 169
Cdd:PLN03211  160 TLVFCSLLRLpkSLTKQEKILVAESVISELGLTKCENTIIGNsfirgISGGERKRVSIAHEMLINPSLLILDEPTSGLDA 239
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 170 ASCFQVVSLMKSLAQGGRTIICTIHQPSAKLFEMFDKLYILSQGQCIFKGVVTNLIPYLKGLGLHCPTYHNPADFIIEVA 249
Cdd:PLN03211  240 TAAYRLVLTLGSLAQKGKTIVTSMHQPSSRVYQMFDSVLVLSEGRCLFFGKGSDAMAYFESVGFSPSFPMNPADFLLDLA 319
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 250 SGeYGDLNPMLFRA---VQNGLCAMAEKKSSPEKNEVPAPCPPCPPEVDPIESHTFA----------TSTLTQFCILFKR 316
Cdd:PLN03211  320 NG-VCQTDGVSEREkpnVKQSLVASYNTLLAPKVKAAIEMSHFPQANARFVGSASTKehrssdrisiSTWFNQFSILLQR 398
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 317 TfLSILRDTVLTHLRFMSHVVIGVLIGLLYLHigDDASKVFNNTGCLFFSMLFLMFAALMPTVLTFPLEMAVFMREHLNY 396
Cdd:PLN03211  399 S-LKERKHESFNTLRVFQVIAAALLAGLMWWH--SDFRDVQDRLGLLFFISIFWGVFPSFNSVFVFPQERAIFVKERASG 475
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 397 WYSLKAYYLAKTMADVPFQVVCPVVYCSIVYWMTGQPAETSRFLLFSALATATALVAQSLGLLIGAASNSLQVATFVGPV 476
Cdd:PLN03211  476 MYTLSSYFMARIVGDLPMELILPTIFLTVTYWMAGLKPELGAFLLTLLVLLGYVLVSQGLGLALGAAIMDAKKASTIVTV 555
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 477 TAIPVLLFSGFFVSfkTIPTYLQWSSYLSYVRYGFEGVILTIYGMERGDLTCLEERCPFREPQSILRALDVE---DAKLY 553
Cdd:PLN03211  556 TMLAFVLTGGFYVH--KLPSCMAWIKYISTTFYSYRLLINVQYGEGKRISSLLGCSLPHGSDRASCKFVEEDvagQISPA 633
                         570       580
                  ....*....|....*....|....*..
gi 2462526932 554 MDFLVLGIFFLALRLLAYLVLRyRVKS 580
Cdd:PLN03211  634 TSVSVLIFMFVGYRLLAYLALR-RIKH 659
3a01205 TIGR00956
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
13-520 4.01e-65

Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273362 [Multi-domain]  Cd Length: 1394  Bit Score: 231.54  E-value: 4.01e-65
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932   13 VASGYKTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAGYRESGM--KGQILVNGRPRElRTFRKMSCYIMQDDMLLP 90
Cdd:TIGR00956  771 IKKEKRVILNNVDGWVKPGTLTALMGASGAGKTTLLNVLAERVTTGVitGGDRLVNGRPLD-SSFQRSIGYVQQQDLHLP 849
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932   91 HLTVLEAMMVSANLKLSEK--QEVKKELVTEILTALGLMSCSHTRTAL----LSGGQRKRLAIALELVNNPP-VMFFDEP 163
Cdd:TIGR00956  850 TSTVRESLRFSAYLRQPKSvsKSEKMEYVEEVIKLLEMESYADAVVGVpgegLNVEQRKRLTIGVELVAKPKlLLFLDEP 929
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  164 TSGLDSASCFQVVSLMKSLAQGGRTIICTIHQPSAKLFEMFDKLYILSQG-QCIFKGVV----TNLIPYLKGLGLH-CPT 237
Cdd:TIGR00956  930 TSGLDSQTAWSICKLMRKLADHGQAILCTIHQPSAILFEEFDRLLLLQKGgQTVYFGDLgensHTIINYFEKHGAPkCPE 1009
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  238 YHNPADFIIEVASGEYGD----------LNPMLFRAVQNGLCAM------AEKKSSPEKNevpapcppcppevdpiesHT 301
Cdd:TIGR00956 1010 DANPAEWMLEVIGAAPGAhanqdyhevwRNSSEYQAVKNELDRLeaelskAEDDNDPDAL------------------SK 1071
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  302 FATSTLTQFCILFKRTFLSILRDTVLTHLRFMSHVVIGVLIGLLYLHIGDDASKVFNNTGCLFfsMLFLMFAALMPTVL- 380
Cdd:TIGR00956 1072 YAASLWYQFKLVLWRTFQQYWRTPDYLYSKFFLTIFAALFIGFTFFKVGTSLQGLQNQMFAVF--MATVLFNPLIQQYLp 1149
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  381 TF-PLEMAVFMREHLNYWYSLKAYYLAKTMADVPFQVVCPVVYCSIVYWMTG-------QPAETSRFLLFSALATATALV 452
Cdd:TIGR00956 1150 PFvAQRDLYEVRERPSRTFSWLAFIAAQITVEIPYNLVAGTIFFFIWYYPVGfywnaskTGQVHERGVLFWLLSTMFFLY 1229
                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2462526932  453 AQSLGLLIGAASNSLQVATFVGPVTAIPVLLFSGFFVSFKTIPTYLQWSSYLSYVRYGFEGVILTIYG 520
Cdd:TIGR00956 1230 FSTLGQMVISFNPNADNAAVLASLLFTMCLSFCGVLAPPSRMPGFWIFMYRCSPFTYLVQALLSTGLA 1297
ABCG_White cd03234
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ...
17-219 3.61e-60

White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.


Pssm-ID: 213201 [Multi-domain]  Cd Length: 226  Bit Score: 199.42  E-value: 3.61e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  17 YKTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAGYRESG--MKGQILVNGRPRELRTFRKMSCYIMQDDMLLPHLTV 94
Cdd:cd03234    19 YARILNDVSLHVESGQVMAILGSSGSGKTTLLDAISGRVEGGgtTSGQILFNGQPRKPDQFQKCVAYVRQDDILLPGLTV 98
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  95 LEAMMVSANLKLSEKQ---EVKKELVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSAS 171
Cdd:cd03234    99 RETLTYTAILRLPRKSsdaIRKKRVEDVLLRDLALTRIGGNLVKGISGGERRRVSIAVQLLWDPKVLILDEPTSGLDSFT 178
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 2462526932 172 CFQVVSLMKSLAQGGRTIICTIHQPSAKLFEMFDKLYILSQGQCIFKG 219
Cdd:cd03234   179 ALNLVSTLSQLARRNRIVILTIHQPRSDLFRLFDRILLLSSGEIVYSG 226
PLN03140 PLN03140
ABC transporter G family member; Provisional
20-520 2.49e-54

ABC transporter G family member; Provisional


Pssm-ID: 215599 [Multi-domain]  Cd Length: 1470  Bit Score: 199.69  E-value: 2.49e-54
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932   20 LLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAGYRESG-MKGQILVNGRPRELRTFRKMSCYIMQDDMLLPHLTVLEAM 98
Cdd:PLN03140   895 LLREVTGAFRPGVLTALMGVSGAGKTTLMDVLAGRKTGGyIEGDIRISGFPKKQETFARISGYCEQNDIHSPQVTVRESL 974
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932   99 MVSANLKLSekQEVKKE----LVTEILTALGLMSCSHTRTAL-----LSGGQRKRLAIALELVNNPPVMFFDEPTSGLDS 169
Cdd:PLN03140   975 IYSAFLRLP--KEVSKEekmmFVDEVMELVELDNLKDAIVGLpgvtgLSTEQRKRLTIAVELVANPSIIFMDEPTSGLDA 1052
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  170 ASCFQVVSLMKSLAQGGRTIICTIHQPSAKLFEMFDKLYILSQ-GQCIFKGVV----TNLIPYLKGL-GL-HCPTYHNPA 242
Cdd:PLN03140  1053 RAAAIVMRTVRNTVDTGRTVVCTIHQPSIDIFEAFDELLLMKRgGQVIYSGPLgrnsHKIIEYFEAIpGVpKIKEKYNPA 1132
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  243 DFIIEVASgeygdlnpmLFRAVQNGLCAMAEKKSSP----EKNEVPAPCPPCPPEVDPIESHTFATSTLTQFCILFKRTF 318
Cdd:PLN03140  1133 TWMLEVSS---------LAAEVKLGIDFAEHYKSSSlyqrNKALVKELSTPPPGASDLYFATQYSQSTWGQFKSCLWKQW 1203
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  319 LSILRDTVLTHLRFMSHVVIGVLIGLLYLHIG---DDASKVFNNTGCLFFSMLFLMFAALMPTVLTFPLEMAVFMREHLN 395
Cdd:PLN03140  1204 WTYWRSPDYNLVRFFFTLAAALMVGTIFWKVGtkrSNANDLTMVIGAMYAAVLFVGINNCSTVQPMVAVERTVFYRERAA 1283
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  396 YWYSLKAYYLAKTMADVPFQVVCPVVYCSIVYWMTGQPAETSRFLLFSALATATALVAQSLGLLIGAASNSLQVAT-FVG 474
Cdd:PLN03140  1284 GMYSALPYAIAQVVCEIPYVLIQTTYYTLIVYAMVAFEWTAAKFFWFYFISFFSFLYFTYYGMMTVSLTPNQQVAAiFAA 1363
                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....*.
gi 2462526932  475 PVTAIpVLLFSGFFVSFKTIPTYLQWSSYLSYVRYGFEGVILTIYG 520
Cdd:PLN03140  1364 AFYGL-FNLFSGFFIPRPKIPKWWVWYYWICPVAWTVYGLIVSQYG 1408
ABCG_PDR_domain2 cd03232
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding ...
13-219 4.88e-54

Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213199 [Multi-domain]  Cd Length: 192  Bit Score: 182.06  E-value: 4.88e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  13 VASGYKTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAGYRESG-MKGQILVNGRPRElRTFRKMSCYIMQDDMLLPH 91
Cdd:cd03232    15 VKGGKRQLLNNISGYVKPGTLTALMGESGAGKTTLLDVLAGRKTAGvITGEILINGRPLD-KNFQRSTGYVEQQDVHSPN 93
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  92 LTVLEAMMVSANLKlsekqevkkelvteiltalGLmscshtrtallSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSAS 171
Cdd:cd03232    94 LTVREALRFSALLR-------------------GL-----------SVEQRKRLTIGVELAAKPSILFLDEPTSGLDSQA 143
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 2462526932 172 CFQVVSLMKSLAQGGRTIICTIHQPSAKLFEMFDKLYILSQ-GQCIFKG 219
Cdd:cd03232   144 AYNIVRFLKKLADSGQAILCTIHQPSASIFEKFDRLLLLKRgGKTVYFG 192
3a01205 TIGR00956
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
3-515 1.48e-51

Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273362 [Multi-domain]  Cd Length: 1394  Bit Score: 191.09  E-value: 1.48e-51
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932    3 GFSHAFQKRivASGYKTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAGYRES---GMKGQILVNGRPRE--LRTFRK 77
Cdd:TIGR00956   61 GFRKLKKFR--DTKTFDILKPMDGLIKPGELTVVLGRPGSGCSTLLKTIASNTDGfhiGVEGVITYDGITPEeiKKHYRG 138
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932   78 MSCYIMQDDMLLPHLTVLEAMMVSANLK-------LSEKQEVKKELVTEILTALGLmscSHTRTAL--------LSGGQR 142
Cdd:TIGR00956  139 DVVYNAETDVHFPHLTVGETLDFAARCKtpqnrpdGVSREEYAKHIADVYMATYGL---SHTRNTKvgndfvrgVSGGER 215
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  143 KRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKSLAQ-GGRTIICTIHQPSAKLFEMFDKLYILSQGQCIFKGVV 221
Cdd:TIGR00956  216 KRVSIAEASLGGAKIQCWDNATRGLDSATALEFIRALKTSANiLDTTPLVAIYQCSQDAYELFDKVIVLYEGYQIYFGPA 295
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  222 TNLIPYLKGLGLHCPTYHNPADFIIEVAS-------GEYGDLNPM-------LFRAVQNGLCAMAEKKSSPEKNEVPAPC 287
Cdd:TIGR00956  296 DKAKQYFEKMGFKCPDRQTTADFLTSLTSpaerqikPGYEKKVPRtpqefetYWRNSPEYAQLMKEIDEYLDRCSESDTK 375
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  288 PPCPPEVDPIES-HTFATSTLT-----QFCILFKRTFLSILRDTVLTHLRFMSHVVIGVLIGLLYLHIGDDASKVFNNTG 361
Cdd:TIGR00956  376 EAYRESHVAKQSkRTRPSSPYTvsfsmQVKYCLARNFLRMKGNPSFTLFMVFGNIIMALILSSVFYNLPKNTSDFYSRGG 455
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  362 CLFFSMLFLMFAALMPTVLTFplEMAVFMREHLNY-WYSLKAYYLAKTMADVPFQVVCPVVYCSIVYWMTGQPAETSRFL 440
Cdd:TIGR00956  456 ALFFAILFNAFSSLLEIASMY--EARPIVEKHRKYaLYHPSADAIASIISEIPFKIIESVVFNIILYFMVNFRRTAGRFF 533
                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2462526932  441 LFSALATATALVAQSLGLLIGAASNSLQVATFVGPVTAIPVLLFSGFFVSFKTIPTYLQWSSYLSYVRYGFEGVI 515
Cdd:TIGR00956  534 FYLLILFICTLAMSHLFRSIGAVTKTLSEAMTPAAILLLALSIYTGFAIPRPSMLGWSKWIYYVNPLAYAFESLM 608
ABC2_membrane pfam01061
ABC-2 type transporter;
313-515 2.42e-46

ABC-2 type transporter;


Pssm-ID: 426023 [Multi-domain]  Cd Length: 204  Bit Score: 161.67  E-value: 2.42e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 313 LFKRTFLSILRDTVLTHLRFMSHVVIGVLIGLLYLHIGDDASkVFNNTGCLFFSMLFLMFAALMPTVLTFPLEMAVFMRE 392
Cdd:pfam01061   1 LLKREFLRRWRDPSLGLWRLIQPILMALIFGTLFGNLGNQQG-GLNRPGLLFFSILFNAFSALSGISPVFEKERGVLYRE 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 393 HLNYWYSLKAYYLAKTMADVPFQVVCPVVYCSIVYWMTGQPAETSRFLLFSALATATALVAQSLGLLIGAASNSLQVATF 472
Cdd:pfam01061  80 LASPLYSPSAYVLAKILSELPLSLLQSLIFLLIVYFMVGLPPSAGRFFLFLLVLLLTALAASSLGLFISALAPSFEDASQ 159
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 2462526932 473 VGPVTAIPVLLFSGFFVSFKTIPTYLQWSSYLSYVRYGFEGVI 515
Cdd:pfam01061 160 LGPLVLLPLLLLSGFFIPIDSMPVWWQWIYYLNPLTYAIEALR 202
CcmA COG1131
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
32-225 3.94e-42

ABC-type multidrug transport system, ATPase component [Defense mechanisms];


Pssm-ID: 440746 [Multi-domain]  Cd Length: 236  Bit Score: 151.37  E-value: 3.94e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  32 ELIGIMGPSGAGKSTFMNILAGYRESGmKGQILVNGRP--RELRTFRKMSCYIMQDDMLLPHLTVLEAMMVSANLK-LSE 108
Cdd:COG1131    27 EIFGLLGPNGAGKTTTIRMLLGLLRPT-SGEVRVLGEDvaRDPAEVRRRIGYVPQEPALYPDLTVRENLRFFARLYgLPR 105
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 109 KQevKKELVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKSLAQGGRT 188
Cdd:COG1131   106 KE--ARERIDELLELFGLTDAADRKVGTLSGGMKQRLGLALALLHDPELLILDEPTSGLDPEARRELWELLRELAAEGKT 183
                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 2462526932 189 IICTIHQPSAkLFEMFDKLYILSQGQCIFKGVVTNLI 225
Cdd:COG1131   184 VLLSTHYLEE-AERLCDRVAIIDKGRIVADGTPDELK 219
ABC_cobalt_CbiO_domain1 cd03225
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ...
15-214 1.62e-41

First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.


Pssm-ID: 213192 [Multi-domain]  Cd Length: 211  Bit Score: 148.77  E-value: 1.62e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  15 SGYKTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAGYRESgMKGQILVNGRP---RELRTFRKMSCYIMQ--DDMLL 89
Cdd:cd03225    11 DGARPALDDISLTIKKGEFVLIVGPNGSGKSTLLRLLNGLLGP-TSGEVLVDGKDltkLSLKELRRKVGLVFQnpDDQFF 89
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  90 pHLTVLEAMMVSA-NLKLSEKQEVKKelVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLD 168
Cdd:cd03225    90 -GPTVEEEVAFGLeNLGLPEEEIEER--VEEALELVGLEGLRDRSPFTLSGGQKQRVAIAGVLAMDPDILLLDEPTAGLD 166
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 2462526932 169 SASCFQVVSLMKSLAQGGRTIICTIHQPSaKLFEMFDKLYILSQGQ 214
Cdd:cd03225   167 PAGRRELLELLKKLKAEGKTIIIVTHDLD-LLLELADRVIVLEDGK 211
LolD COG1136
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];
30-214 2.47e-40

ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440751 [Multi-domain]  Cd Length: 227  Bit Score: 146.34  E-value: 2.47e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  30 RRELIGIMGPSGAGKSTFMNILAgyresGM----KGQILVNGRP------RELRTFRKMSC-YIMQDDMLLPHLTVLEAM 98
Cdd:COG1136    33 AGEFVAIVGPSGSGKSTLLNILG-----GLdrptSGEVLIDGQDisslseRELARLRRRHIgFVFQFFNLLPELTALENV 107
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  99 MVSANLKlSEKQEVKKELVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSL 178
Cdd:COG1136   108 ALPLLLA-GVSRKERRERARELLERVGLGDRLDHRPSQLSGGQQQRVAIARALVNRPKLILADEPTGNLDSKTGEEVLEL 186
                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 2462526932 179 MKSLA-QGGRTIICTIHqpSAKLFEMFDKLYILSQGQ 214
Cdd:COG1136   187 LRELNrELGTTIVMVTH--DPELAARADRVIRLRDGR 221
EcfA2 COG1122
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ...
18-219 9.65e-39

Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];


Pssm-ID: 440739 [Multi-domain]  Cd Length: 230  Bit Score: 142.09  E-value: 9.65e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  18 KTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAG-YRESgmKGQILVNGRP---RELRTFRKMSCYIMQ--DDMLLpH 91
Cdd:COG1122    14 TPALDDVSLSIEKGEFVAIIGPNGSGKSTLLRLLNGlLKPT--SGEVLVDGKDitkKNLRELRRKVGLVFQnpDDQLF-A 90
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  92 LTVLEAMMVS-ANLKLSEKqEVKkELVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSA 170
Cdd:COG1122    91 PTVEEDVAFGpENLGLPRE-EIR-ERVEEALELVGLEHLADRPPHELSGGQKQRVAIAGVLAMEPEVLVLDEPTAGLDPR 168
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 2462526932 171 SCFQVVSLMKSLAQGGRTIICTIHQPSAkLFEMFDKLYILSQGQCIFKG 219
Cdd:COG1122   169 GRRELLELLKRLNKEGKTVIIVTHDLDL-VAELADRVIVLDDGRIVADG 216
ABC_MJ0796_LolCDE_FtsE cd03255
ATP-binding cassette domain of the transporters involved in export of lipoprotein and ...
32-214 3.71e-38

ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.


Pssm-ID: 213222 [Multi-domain]  Cd Length: 218  Bit Score: 139.93  E-value: 3.71e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  32 ELIGIMGPSGAGKSTFMNILAGyRESGMKGQILVNGRP------RELRTFR--KMScYIMQDDMLLPHLTVLEAMMVSAN 103
Cdd:cd03255    31 EFVAIVGPSGSGKSTLLNILGG-LDRPTSGEVRVDGTDisklseKELAAFRrrHIG-FVFQSFNLLPDLTALENVELPLL 108
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 104 LKLSEKQEvKKELVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKSLA 183
Cdd:cd03255   109 LAGVPKKE-RRERAEELLERVGLGDRLNHYPSELSGGQQQRVAIARALANDPKIILADEPTGNLDSETGKEVMELLRELN 187
                         170       180       190
                  ....*....|....*....|....*....|..
gi 2462526932 184 -QGGRTIICTIHQPSakLFEMFDKLYILSQGQ 214
Cdd:cd03255   188 kEAGTTIVVVTHDPE--LAEYADRIIELRDGK 217
NatA COG4555
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, ...
32-221 4.09e-36

ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 443618 [Multi-domain]  Cd Length: 243  Bit Score: 135.37  E-value: 4.09e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  32 ELIGIMGPSGAGKSTFMNILAGYRESGmKGQILVNGRP--RELRTFRKMSCYIMQDDMLLPHLTVLEAMMVSANLKLSEK 109
Cdd:COG4555    28 EITGLLGPNGAGKTTLLRMLAGLLKPD-SGSILIDGEDvrKEPREARRQIGVLPDERGLYDRLTVRENIRYFAELYGLFD 106
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 110 QEVKKElVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKSLAQGGRTI 189
Cdd:COG4555   107 EELKKR-IEELIELLGLEEFLDRRVGELSTGMKKKVALARALVHDPKVLLLDEPTNGLDVMARRLLREILRALKKEGKTV 185
                         170       180       190
                  ....*....|....*....|....*....|....
gi 2462526932 190 ICTIHQPS--AKLfemFDKLYILSQGQCIFKGVV 221
Cdd:COG4555   186 LFSSHIMQevEAL---CDRVVILHKGKVVAQGSL 216
ABC_subfamily_A cd03263
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ...
15-216 1.38e-35

ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.


Pssm-ID: 213230 [Multi-domain]  Cd Length: 220  Bit Score: 133.01  E-value: 1.38e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  15 SGYKTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAGyRESGMKGQILVNGRP--RELRTFRKMSCYIMQDDMLLPHL 92
Cdd:cd03263    12 KGTKPAVDDLSLNVYKGEIFGLLGHNGAGKTTTLKMLTG-ELRPTSGTAYINGYSirTDRKAARQSLGYCPQFDALFDEL 90
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  93 TVLEAMMVSANLK-LSEKQEvkKELVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSAS 171
Cdd:cd03263    91 TVREHLRFYARLKgLPKSEI--KEEVELLLRVLGLTDKANKRARTLSGGMKRKLSLAIALIGGPSVLLLDEPTSGLDPAS 168
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 2462526932 172 CFQVVSLMKSLaQGGRTIICTIHqpSAKLFEMF-DKLYILSQGQ--CI 216
Cdd:cd03263   169 RRAIWDLILEV-RKGRSIILTTH--SMDEAEALcDRIAIMSDGKlrCI 213
ABC_Org_Solvent_Resistant cd03261
ATP-binding cassette transport system involved in resistance to organic solvents; ABC ...
16-219 2.75e-35

ATP-binding cassette transport system involved in resistance to organic solvents; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213228 [Multi-domain]  Cd Length: 235  Bit Score: 132.63  E-value: 2.75e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  16 GYKTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAG-YRESgmKGQILVNGRPR------ELRTFRKMSCYIMQDDML 88
Cdd:cd03261    11 GGRTVLKGVDLDVRRGEILAIIGPSGSGKSTLLRLIVGlLRPD--SGEVLIDGEDIsglseaELYRLRRRMGMLFQSGAL 88
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  89 LPHLTVLE--AMMVSANLKLSEkqEVKKELVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSG 166
Cdd:cd03261    89 FDSLTVFEnvAFPLREHTRLSE--EEIREIVLEKLEAVGLRGAEDLYPAELSGGMKKRVALARALALDPELLLYDEPTAG 166
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2462526932 167 LDSASCFQVVSLMKSL--AQGGRTIICTiHQPSAkLFEMFDKLYILSQGQCIFKG 219
Cdd:cd03261   167 LDPIASGVIDDLIRSLkkELGLTSIMVT-HDLDT-AFAIADRIAVLYDGKIVAEG 219
ABC_PhnC_transporter cd03256
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; ...
15-219 1.94e-34

ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Phosphonates are widespread among naturally occurring compounds in all kingdoms of wildlife, but only prokaryotic microorganisms are able to cleave this bond. Certain bacteria such as E. coli can use alkylphosphonates as a phosphorus source. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213223 [Multi-domain]  Cd Length: 241  Bit Score: 130.38  E-value: 1.94e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  15 SGYKTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAGYREsGMKGQILVNG------RPRELRTFRKMSCYIMQDDML 88
Cdd:cd03256    11 PNGKKALKDVSLSINPGEFVALIGPSGAGKSTLLRCLNGLVE-PTSGSVLIDGtdinklKGKALRQLRRQIGMIFQQFNL 89
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  89 LPHLTVLEAMMV---------SANLKLSEKQEvkKELVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMF 159
Cdd:cd03256    90 IERLSVLENVLSgrlgrrstwRSLFGLFPKEE--KQRALAALERVGLLDKAYQRADQLSGGQQQRVAIARALMQQPKLIL 167
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462526932 160 FDEPTSGLDSASCFQVVSLMKSLAQG-GRTIICTIHQPS-AKLFemFDKLYILSQGQCIFKG 219
Cdd:cd03256   168 ADEPVASLDPASSRQVMDLLKRINREeGITVIVSLHQVDlAREY--ADRIVGLKDGRIVFDG 227
ABC_tran pfam00005
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ...
21-165 1.32e-33

ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.


Pssm-ID: 394964 [Multi-domain]  Cd Length: 150  Bit Score: 125.07  E-value: 1.32e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  21 LKCLSGKFCRRELIGIMGPSGAGKSTFMNILAGyRESGMKGQILVNGRP---RELRTFRKMSCYIMQDDMLLPHLTVLEA 97
Cdd:pfam00005   1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAG-LLSPTEGTILLDGQDltdDERKSLRKEIGYVFQDPQLFPRLTVREN 79
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462526932  98 MMVSANLKLSEKQEVKKElVTEILTALGLMSCSHTR----TALLSGGQRKRLAIALELVNNPPVMFFDEPTS 165
Cdd:pfam00005  80 LRLGLLLKGLSKREKDAR-AEEALEKLGLGDLADRPvgerPGTLSGGQRQRVAIARALLTKPKLLLLDEPTA 150
PLN03140 PLN03140
ABC transporter G family member; Provisional
19-514 5.63e-33

ABC transporter G family member; Provisional


Pssm-ID: 215599 [Multi-domain]  Cd Length: 1470  Bit Score: 135.36  E-value: 5.63e-33
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932   19 TLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAGYRESGMK--GQILVNGRprELRTF--RKMSCYIMQDDMLLPHLTV 94
Cdd:PLN03140   179 TILKDASGIIKPSRMTLLLGPPSSGKTTLLLALAGKLDPSLKvsGEITYNGY--RLNEFvpRKTSAYISQNDVHVGVMTV 256
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932   95 LEAMMVSAN--------------------------------LKLSEKQEVKKELVTE-ILTALGLMSCSHTRTAL----- 136
Cdd:PLN03140   257 KETLDFSARcqgvgtrydllselarrekdagifpeaevdlfMKATAMEGVKSSLITDyTLKILGLDICKDTIVGDemirg 336
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  137 LSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKSLAQ-GGRTIICTIHQPSAKLFEMFDKLYILSQGQC 215
Cdd:PLN03140   337 ISGGQKKRVTTGEMIVGPTKTLFMDEISTGLDSSTTYQIVKCLQQIVHlTEATVLMSLLQPAPETFDLFDDIILLSEGQI 416
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  216 IFKGVVTNLIPYLKGLGLHCPTYHNPADFIIEVASGE-----YGDLN-PMLFRAV----------------QNGLCAMAE 273
Cdd:PLN03140   417 VYQGPRDHILEFFESCGFKCPERKGTADFLQEVTSKKdqeqyWADRNkPYRYISVsefaerfksfhvgmqlENELSVPFD 496
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  274 KKSSPEknevpapcppcppEVDPIESHTFATSTLTQFCilFKRTFLSILRDTVLTHLRFMSHVVIGVLIGLLYLHI---- 349
Cdd:PLN03140   497 KSQSHK-------------AALVFSKYSVPKMELLKAC--WDKEWLLMKRNAFVYVFKTVQIIIVAAIASTVFLRTemht 561
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  350 ---GDDASKVfnntGCLFFSMLFLMFAALMPTVLTFPlEMAVFMRE-----HLNYWYSLKAYYLAktmadVPFQVVCPVV 421
Cdd:PLN03140   562 rneEDGALYI----GALLFSMIINMFNGFAELALMIQ-RLPVFYKQrdllfHPPWTFTLPTFLLG-----IPISIIESVV 631
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  422 YCSIVYWMTGQPAETSRFLLFSALATATALVAQSLGLLIGAASNSLQVATFVGPVTAIPVLLFSGFFVSFKTIPTYLQWS 501
Cdd:PLN03140   632 WVVITYYSIGFAPEASRFFKQLLLVFLIQQMAAGIFRLIASVCRTMIIANTGGALVLLLVFLLGGFILPKGEIPNWWEWA 711
                          570
                   ....*....|...
gi 2462526932  502 SYLSYVRYGFEGV 514
Cdd:PLN03140   712 YWVSPLSYGFNAL 724
ABC_DR_subfamily_A cd03230
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ...
18-214 5.82e-33

ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213197 [Multi-domain]  Cd Length: 173  Bit Score: 124.05  E-value: 5.82e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  18 KTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAGYRESGmKGQILVNGRP--RELRTFRKMSCYIMQDDMLLPHLTVL 95
Cdd:cd03230    13 KTALDDISLTVEKGEIYGLLGPNGAGKTTLIKIILGLLKPD-SGEIKVLGKDikKEPEEVKRRIGYLPEEPSLYENLTVR 91
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  96 EammvsaNLKLSekqevkkelvteiltalglmscshtrtallsGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQV 175
Cdd:cd03230    92 E------NLKLS-------------------------------GGMKQRLALAQALLHDPELLILDEPTSGLDPESRREF 134
                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 2462526932 176 VSLMKSLAQGGRTIICTIHQPSAkLFEMFDKLYILSQGQ 214
Cdd:cd03230   135 WELLRELKKEGKTILLSSHILEE-AERLCDRVAILNNGR 172
ABC_drug_resistance_like cd03264
ABC-type multidrug transport system, ATPase component; The biological function of this family ...
33-219 4.30e-32

ABC-type multidrug transport system, ATPase component; The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213231 [Multi-domain]  Cd Length: 211  Bit Score: 123.07  E-value: 4.30e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  33 LIGIMGPSGAGKSTFMNILAGYRESGmKGQILVNGRP--RELRTFRKMSCYIMQDDMLLPHLTVLEAMMVSANLKLSEKQ 110
Cdd:cd03264    27 MYGLLGPNGAGKTTLMRILATLTPPS-SGTIRIDGQDvlKQPQKLRRRIGYLPQEFGVYPNFTVREFLDYIAWLKGIPSK 105
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 111 EVKKElVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKSLAQgGRTII 190
Cdd:cd03264   106 EVKAR-VDEVLELVNLGDRAKKKIGSLSGGMRRRVGIAQALVGDPSILIVDEPTAGLDPEERIRFRNLLSELGE-DRIVI 183
                         170       180
                  ....*....|....*....|....*....
gi 2462526932 191 CTIHQPSaKLFEMFDKLYILSQGQCIFKG 219
Cdd:cd03264   184 LSTHIVE-DVESLCNQVAVLNKGKLVFEG 211
ABC_Class3 cd03229
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is ...
16-214 5.64e-32

ATP-binding cassette domain of the binding protein-dependent transport systems; This class is comprised of all BPD (Binding Protein Dependent) systems that are largely represented in archaea and eubacteria and are primarily involved in scavenging solutes from the environment. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213196 [Multi-domain]  Cd Length: 178  Bit Score: 121.53  E-value: 5.64e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  16 GYKTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAGYrESGMKGQILVNGRP-----RELRTFRKMSCYIMQDDMLLP 90
Cdd:cd03229    11 GQKTVLNDVSLNIEAGEIVALLGPSGSGKSTLLRCIAGL-EEPDSGSILIDGEDltdleDELPPLRRRIGMVFQDFALFP 89
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  91 HLTVLEammvsaNLklsekqevkkelvteiltALGLmscshtrtallSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSA 170
Cdd:cd03229    90 HLTVLE------NI------------------ALGL-----------SGGQQQRVALARALAMDPDVLLLDEPTSALDPI 134
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 2462526932 171 SCFQVVSLMKSL-AQGGRTIICTIHQPsAKLFEMFDKLYILSQGQ 214
Cdd:cd03229   135 TRREVRALLKSLqAQLGITVVLVTHDL-DEAARLADRVVVLRDGK 178
FetA COG4619
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];
13-214 7.24e-32

ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443661 [Multi-domain]  Cd Length: 209  Bit Score: 122.23  E-value: 7.24e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  13 VASGYKTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAGYrESGMKGQILVNGRPRE---LRTFRKMSCYIMQDdmll 89
Cdd:COG4619     8 FRVGGKPILSPVSLTLEAGECVAITGPSGSGKSTLLRALADL-DPPTSGEIYLDGKPLSampPPEWRRQVAYVPQE---- 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  90 phlTVLEAMMVSANLKLS---EKQEVKKELVTEILTALGL-MSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTS 165
Cdd:COG4619    83 ---PALWGGTVRDNLPFPfqlRERKFDRERALELLERLGLpPDILDKPVERLSGGERQRLALIRALLLQPDVLLLDEPTS 159
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 2462526932 166 GLDSASCFQVVSLMKSL-AQGGRTIICTIHQPsAKLFEMFDKLYILSQGQ 214
Cdd:COG4619   160 ALDPENTRRVEELLREYlAEEGRAVLWVSHDP-EQIERVADRVLTLEAGR 208
ABC_phnC TIGR02315
phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of ...
18-220 3.05e-31

phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of phosphorus-containing organic compound with a stable direct C-P bond rather than a C-O-P linkage. A number of bacterial species have operons, typically about 14 genes in size, with genes for ATP-dependent transport of phosphonates, degradation, and regulation of the expression of the system. Members of this protein family are the ATP-binding cassette component of tripartite ABC transporters of phosphonates. [Transport and binding proteins, Anions]


Pssm-ID: 131368 [Multi-domain]  Cd Length: 243  Bit Score: 121.64  E-value: 3.05e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  18 KTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAGYRESGmKGQILVNG------RPRELRTFRKMSCYIMQDDMLLPH 91
Cdd:TIGR02315  15 KQALKNINLNINPGEFVAIIGPSGAGKSTLLRCINRLVEPS-SGSILLEGtditklRGKKLRKLRRRIGMIFQHYNLIER 93
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  92 LTVLEAMMVSA-------NLKLSEKQEVKKELVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPT 164
Cdd:TIGR02315  94 LTVLENVLHGRlgykptwRSLLGRFSEEDKERALSALERVGLADKAYQRADQLSGGQQQRVAIARALAQQPDLILADEPI 173
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2462526932 165 SGLDSASCFQVVSLMKSLAQG-GRTIICTIHQPS-AKLFEmfDKLYILSQGQCIFKGV 220
Cdd:TIGR02315 174 ASLDPKTSKQVMDYLKRINKEdGITVIINLHQVDlAKKYA--DRIVGLKAGEIVFDGA 229
ABC_FtsE cd03292
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where ...
30-194 4.92e-31

Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages


Pssm-ID: 213259 [Multi-domain]  Cd Length: 214  Bit Score: 120.21  E-value: 4.92e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  30 RRELIGIMGPSGAGKSTFMNILAGyRESGMKGQILVNGRP------RELRTFRKMSCYIMQDDMLLPHLTVLEAMMVSAN 103
Cdd:cd03292    26 AGEFVFLVGPSGAGKSTLLKLIYK-EELPTSGTIRVNGQDvsdlrgRAIPYLRRKIGVVFQDFRLLPDRNVYENVAFALE 104
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 104 LKLSEKQEVKKElVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKSLA 183
Cdd:cd03292   105 VTGVPPREIRKR-VPAALELVGLSHKHRALPAELSGGEQQRVAIARAIVNSPTILIADEPTGNLDPDTTWEIMNLLKKIN 183
                         170
                  ....*....|.
gi 2462526932 184 QGGRTIICTIH 194
Cdd:cd03292   184 KAGTTVVVATH 194
ABC_cobalt_CbiO_domain2 cd03226
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of ...
18-194 6.92e-31

Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. The CbiMNQO family ABC transport system is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.


Pssm-ID: 213193 [Multi-domain]  Cd Length: 205  Bit Score: 119.28  E-value: 6.92e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  18 KTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAG-YRESgmKGQILVNGRPRELRTFRKMSCYIMQD-DMLLPHLTVL 95
Cdd:cd03226    13 TEILDDLSLDLYAGEIIALTGKNGAGKTTLAKILAGlIKES--SGSILLNGKPIKAKERRKSIGYVMQDvDYQLFTDSVR 90
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  96 EAMMVSANLkLSEKQEVkkelVTEILTALGL--MSCSHTRTalLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCF 173
Cdd:cd03226    91 EELLLGLKE-LDAGNEQ----AETVLKDLDLyaLKERHPLS--LSGGQKQRLAIAAALLSGKDLLIFDEPTSGLDYKNME 163
                         170       180
                  ....*....|....*....|.
gi 2462526932 174 QVVSLMKSLAQGGRTIICTIH 194
Cdd:cd03226   164 RVGELIRELAAQGKAVIVITH 184
CcmA COG4133
ABC-type transport system involved in cytochrome c biogenesis, ATPase component ...
32-196 7.73e-31

ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443308 [Multi-domain]  Cd Length: 206  Bit Score: 119.51  E-value: 7.73e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  32 ELIGIMGPSGAGKSTFMNILAGYRESgMKGQILVNGRPRELR--TFRKMSCYIMQDDMLLPHLTVLEAMMVSANLKlseK 109
Cdd:COG4133    29 EALALTGPNGSGKTTLLRILAGLLPP-SAGEVLWNGEPIRDAreDYRRRLAYLGHADGLKPELTVRENLRFWAALY---G 104
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 110 QEVKKELVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKSLAQGGRTI 189
Cdd:COG4133   105 LRADREAIDEALEAVGLAGLADLPVRQLSAGQKRRVALARLLLSPAPLWLLDEPFTALDAAGVALLAELIAAHLARGGAV 184

                  ....*..
gi 2462526932 190 ICTIHQP 196
Cdd:COG4133   185 LLTTHQP 191
ABC_Mj1267_LivG_branched cd03219
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ...
30-219 9.82e-31

ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).


Pssm-ID: 213186 [Multi-domain]  Cd Length: 236  Bit Score: 119.85  E-value: 9.82e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  30 RRELIGIMGPSGAGKSTFMNILAG-YRESgmKGQILVNGR------PREL------RTFRKMScyimqddmLLPHLTVLE 96
Cdd:cd03219    25 PGEIHGLIGPNGAGKTTLFNLISGfLRPT--SGSVLFDGEditglpPHEIarlgigRTFQIPR--------LFPELTVLE 94
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  97 AMMVSANLKLSE---------KQEVKKELVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGL 167
Cdd:cd03219    95 NVMVAAQARTGSglllararrEEREARERAEELLERVGLADLADRPAGELSYGQQRRLEIARALATDPKLLLLDEPAAGL 174
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2462526932 168 DSASCFQVVSLMKSLAQGGRTIICTIHQPSAkLFEMFDKLYILSQGQCIFKG 219
Cdd:cd03219   175 NPEETEELAELIRELRERGITVLLVEHDMDV-VMSLADRVTVLDQGRVIAEG 225
PhnC COG3638
ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and ...
32-224 1.57e-30

ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 442855 [Multi-domain]  Cd Length: 249  Bit Score: 119.78  E-value: 1.57e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  32 ELIGIMGPSGAGKSTFMNILAGyRESGMKGQILVNG------RPRELRTFRKMSCYIMQDDMLLPHLTVLEAMMV----- 100
Cdd:COG3638    30 EFVALIGPSGAGKSTLLRCLNG-LVEPTSGEILVDGqdvtalRGRALRRLRRRIGMIFQQFNLVPRLSVLTNVLAgrlgr 108
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 101 ----SANLKLSEKQEvkKELVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVV 176
Cdd:COG3638   109 tstwRSLLGLFPPED--RERALEALERVGLADKAYQRADQLSGGQQQRVAIARALVQEPKLILADEPVASLDPKTARQVM 186
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 2462526932 177 SLMKSLAQ-GGRTIICTIHQPS-AKLFemFDKLYILSQGQCIFKGVVTNL 224
Cdd:COG3638   187 DLLRRIAReDGITVVVNLHQVDlARRY--ADRIIGLRDGRVVFDGPPAEL 234
ABCG_PDR_domain1 cd03233
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette ...
18-219 1.60e-30

First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213200 [Multi-domain]  Cd Length: 202  Bit Score: 118.52  E-value: 1.60e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  18 KTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAGYRES--GMKGQILVNGRP--RELRTFRKMSCYIMQDDMLLPHLT 93
Cdd:cd03233    20 IPILKDFSGVVKPGEMVLVLGRPGSGCSTLLKALANRTEGnvSVEGDIHYNGIPykEFAEKYPGEIIYVSEEDVHFPTLT 99
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  94 VLEAMMVSANLKLSEKqeVKKelvteiltalglmscshtrtalLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCF 173
Cdd:cd03233   100 VRETLDFALRCKGNEF--VRG----------------------ISGGERKRVSIAEALVSRASVLCWDNSTRGLDSSTAL 155
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 2462526932 174 QVVSLMKSLAQG-GRTIICTIHQPSAKLFEMFDKLYILSQGQCIFKG 219
Cdd:cd03233   156 EILKCIRTMADVlKTTTFVSLYQASDEIYDLFDKVLVLYEGRQIYYG 202
ABC_ATPase cd00267
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ...
18-214 3.50e-30

ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213179 [Multi-domain]  Cd Length: 157  Bit Score: 115.80  E-value: 3.50e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  18 KTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAGYRESGmKGQILVNGRP---RELRTFRKMSCYIMQddmllphltv 94
Cdd:cd00267    12 RTALDNVSLTLKAGEIVALVGPNGSGKSTLLRAIAGLLKPT-SGEILIDGKDiakLPLEELRRRIGYVPQ---------- 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  95 leammvsanlklsekqevkkelvteiltalglmscshtrtalLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQ 174
Cdd:cd00267    81 ------------------------------------------LSGGQRQRVALARALLLNPDLLLLDEPTSGLDPASRER 118
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 2462526932 175 VVSLMKSLAQGGRTIICTIHQPS-AKLFemFDKLYILSQGQ 214
Cdd:cd00267   119 LLELLRELAEEGRTVIIVTHDPElAELA--ADRVIVLKDGK 157
FepC COG1120
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ...
18-222 7.13e-30

ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];


Pssm-ID: 440737 [Multi-domain]  Cd Length: 254  Bit Score: 118.22  E-value: 7.13e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  18 KTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAGYRESGmKGQILVNGRP------RELRtfRKMScYIMQDDMLLPH 91
Cdd:COG1120    14 RPVLDDVSLSLPPGEVTALLGPNGSGKSTLLRALAGLLKPS-SGEVLLDGRDlaslsrRELA--RRIA-YVPQEPPAPFG 89
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  92 LTVLEAMM------VSANLKLSEKQEvkkELVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTS 165
Cdd:COG1120    90 LTVRELVAlgryphLGLFGRPSAEDR---EAVEEALERTGLEHLADRPVDELSGGERQRVLIARALAQEPPLLLLDEPTS 166
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2462526932 166 GLDSASCFQVVSLMKSLAQG-GRTIICTIHQPS-AKLFemFDKLYILSQGQCIFKG----VVT 222
Cdd:COG1120   167 HLDLAHQLEVLELLRRLARErGRTVVMVLHDLNlAARY--ADRLVLLKDGRIVAQGppeeVLT 227
ABC_HisP_GlnQ cd03262
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ...
32-195 8.76e-30

ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, respectively. Histidine permease is a multi-subunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP. HisP has properties intermediate between those of integral and peripheral membrane proteins and is accessible from both sides of the membrane, presumably by its interaction with HisQ and HisM. The two HisP subunits form a homodimer within the complex. The domain structure of the amino acid uptake systems is typical for prokaryotic extracellular solute binding protein-dependent uptake systems. All of the amino acid uptake systems also have at least one, and in a few cases, two extracellular solute binding proteins located in the periplasm of Gram-negative bacteria, or attached to the cell membrane of Gram-positive bacteria. The best-studied member of the PAAT (polar amino acid transport) family is the HisJQMP system of S. typhimurium, where HisJ is the extracellular solute binding proteins and HisP is the ABC protein.


Pssm-ID: 213229 [Multi-domain]  Cd Length: 213  Bit Score: 116.48  E-value: 8.76e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  32 ELIGIMGPSGAGKSTF---MNILagyrESGMKGQILVNG-----RPRELRTFRKMSCYIMQDDMLLPHLTVLEAMMVSAN 103
Cdd:cd03262    27 EVVVIIGPSGSGKSTLlrcINLL----EEPDSGTIIIDGlkltdDKKNINELRQKVGMVFQQFNLFPHLTVLENITLAPI 102
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 104 --LKLSEKQEVKKELvtEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKS 181
Cdd:cd03262   103 kvKGMSKAEAEERAL--ELLEKVGLADKADAYPAQLSGGQQQRVAIARALAMNPKVMLFDEPTSALDPELVGEVLDVMKD 180
                         170
                  ....*....|....
gi 2462526932 182 LAQGGRTIICTIHQ 195
Cdd:cd03262   181 LAEEGMTMVVVTHE 194
ZnuC COG1121
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ...
16-215 2.40e-29

ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440738 [Multi-domain]  Cd Length: 245  Bit Score: 116.34  E-value: 2.40e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  16 GYKTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAGYRESgMKGQILVNGRPRELRtfRKMSCYIMQD---DMLLPhL 92
Cdd:COG1121    17 GGRPVLEDVSLTIPPGEFVAIVGPNGAGKSTLLKAILGLLPP-TSGTVRLFGKPPRRA--RRRIGYVPQRaevDWDFP-I 92
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  93 TVLEAMM------VSANLKLSEKQevkKELVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSG 166
Cdd:COG1121    93 TVRDVVLmgrygrRGLFRRPSRAD---REAVDEALERVGLEDLADRPIGELSGGQQQRVLLARALAQDPDLLLLDEPFAG 169
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 2462526932 167 LDSASCFQVVSLMKSLAQGGRTIICTIHQPSAkLFEMFDKLYILSQGQC 215
Cdd:COG1121   170 VDAATEEALYELLRELRREGKTILVVTHDLGA-VREYFDRVLLLNRGLV 217
ABC_NrtD_SsuB_transporters cd03293
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ...
30-223 1.72e-28

ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213260 [Multi-domain]  Cd Length: 220  Bit Score: 113.34  E-value: 1.72e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  30 RRELIGIMGPSGAGKSTFMNILAG-YRESGmkGQILVNGRPreLRTFRKMSCYIMQDDMLLPHLTVLEAMMVSANLKLSE 108
Cdd:cd03293    29 EGEFVALVGPSGCGKSTLLRIIAGlERPTS--GEVLVDGEP--VTGPGPDRGYVFQQDALLPWLTVLDNVALGLELQGVP 104
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 109 KQEvKKELVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQV-VSLMKSLAQGGR 187
Cdd:cd03293   105 KAE-ARERAEELLELVGLSGFENAYPHQLSGGMRQRVALARALAVDPDVLLLDEPFSALDALTREQLqEELLDIWRETGK 183
                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 2462526932 188 TIICTIHQPSAKLFeMFDKLYILSQGQCIFKGVVTN 223
Cdd:cd03293   184 TVLLVTHDIDEAVF-LADRVVVLSARPGRIVAEVEV 218
ABC_ThiQ_thiamine_transporter cd03298
ATP-binding cassette domain of the thiamine transport system; Part of the ...
28-219 2.10e-28

ATP-binding cassette domain of the thiamine transport system; Part of the binding-protein-dependent transport system tbpA-thiPQ for thiamine and TPP. Probably responsible for the translocation of thiamine across the membrane. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213265 [Multi-domain]  Cd Length: 211  Bit Score: 112.59  E-value: 2.10e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  28 FCRRELIGIMGPSGAGKSTFMNILAGYrESGMKGQILVNGR------PRElrtfRKMScYIMQDDMLLPHLTVLE--AMM 99
Cdd:cd03298    21 FAQGEITAIVGPSGSGKSTLLNLIAGF-ETPQSGRVLINGVdvtaapPAD----RPVS-MLFQENNLFAHLTVEQnvGLG 94
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 100 VSANLKLSEKQevkKELVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLM 179
Cdd:cd03298    95 LSPGLKLTAED---RQAIEVALARVGLAGLEKRLPGELSGGERQRVALARVLVRDKPVLLLDEPFAALDPALRAEMLDLV 171
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 2462526932 180 KSL-AQGGRTIICTIHQPSAKLfEMFDKLYILSQGQCIFKG 219
Cdd:cd03298   172 LDLhAETKMTVLMVTHQPEDAK-RLAQRVVFLDNGRIAAQG 211
MlaF COG1127
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall ...
18-219 4.14e-28

ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440744 [Multi-domain]  Cd Length: 241  Bit Score: 112.77  E-value: 4.14e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  18 KTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAGYRESgMKGQILVNGR------PRELRTFR-KMScYIMQDDMLLP 90
Cdd:COG1127    18 RVVLDGVSLDVPRGEILAIIGGSGSGKSVLLKLIIGLLRP-DSGEILVDGQditglsEKELYELRrRIG-MLFQGGALFD 95
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  91 HLTVLE--AMMVSANLKLSEKQevKKELVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLD 168
Cdd:COG1127    96 SLTVFEnvAFPLREHTDLSEAE--IRELVLEKLELVGLPGAADKMPSELSGGMRKRVALARALALDPEILLYDEPTAGLD 173
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2462526932 169 SASCFQVVSLMKSL--AQGGRTIICTiHQ-PSAklFEMFDKLYILSQGQCIFKG 219
Cdd:COG1127   174 PITSAVIDELIRELrdELGLTSVVVT-HDlDSA--FAIADRVAVLADGKIIAEG 224
ABC_Iron-Siderophores_B12_Hemin cd03214
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ...
18-219 9.17e-28

ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.


Pssm-ID: 213181 [Multi-domain]  Cd Length: 180  Bit Score: 109.83  E-value: 9.17e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  18 KTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAGYRESGmKGQILVNGRPRELRTFRKMSCYIMqddmLLPhlTVLEA 97
Cdd:cd03214    12 RTVLDDLSLSIEAGEIVGILGPNGAGKSTLLKTLAGLLKPS-SGEILLDGKDLASLSPKELARKIA----YVP--QALEL 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  98 MMVSAnlkLSEKQevkkelVTEiltalglmscshtrtalLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVS 177
Cdd:cd03214    85 LGLAH---LADRP------FNE-----------------LSGGERQRVLLARALAQEPPILLLDEPTSHLDIAHQIELLE 138
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 2462526932 178 LMKSLA-QGGRTIICTIHQPS-AKLFemFDKLYILSQGQCIFKG 219
Cdd:cd03214   139 LLRRLArERGKTVVMVLHDLNlAARY--ADRVILLKDGRIVAQG 180
ABCC_MRP_Like cd03228
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP ...
15-214 2.24e-27

ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP (Multidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export. They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins. The ABCC subfamily contains transporters with a diverse functional spectrum that includes ion transport, cell surface receptor, and toxin secretion activities. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains, each composed of six transmembrane (TM) helices, and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213195 [Multi-domain]  Cd Length: 171  Bit Score: 108.24  E-value: 2.24e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  15 SGYKTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAGYRESGmKGQILVNGRP-REL--RTFRKMSCYIMQDDMLLpH 91
Cdd:cd03228    12 GRPKPVLKDVSLTIKPGEKVAIVGPSGSGKSTLLKLLLRLYDPT-SGEILIDGVDlRDLdlESLRKNIAYVPQDPFLF-S 89
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  92 LTVLEammvsaNLklsekqevkkelvteiltalglmscshtrtalLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSAS 171
Cdd:cd03228    90 GTIRE------NI--------------------------------LSGGQRQRIAIARALLRDPPILILDEATSALDPET 131
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 2462526932 172 CFQVVSLMKSLAQgGRTIICTIHQPSakLFEMFDKLYILSQGQ 214
Cdd:cd03228   132 EALILEALRALAK-GKTVIVIAHRLS--TIRDADRIIVLDDGR 171
cbiO TIGR01166
cobalt transport protein ATP-binding subunit; This model describes the ATP binding subunit of ...
21-194 5.23e-27

cobalt transport protein ATP-binding subunit; This model describes the ATP binding subunit of the multisubunit cobalt transporter in bacteria and its equivalents in archaea. The model is restricted to ATP subunit that is a part of the cobalt transporter, which belongs to the ABC transporter superfamily (ATP Binding Cassette). The model excludes ATP binding subunit that are associated with other transporters belonging to ABC transporter superfamily. This superfamily includes two groups, one which catalyze the uptake of small molecules, including ions from the external milieu and the other group which is engaged in the efflux of small molecular weight compounds and ions from within the cell. Energy derived from the hydrolysis of ATP drive the both the process of uptake and efflux. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 130234 [Multi-domain]  Cd Length: 190  Bit Score: 107.89  E-value: 5.23e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  21 LKCLSGKFCRRELIGIMGPSGAGKSTFMNILAGYRESgMKGQILVNGRP-----RELRTFRKMSCYIMQD-DMLLPHLTV 94
Cdd:TIGR01166   8 LKGLNFAAERGEVLALLGANGAGKSTLLLHLNGLLRP-QSGAVLIDGEPldysrKGLLERRQRVGLVFQDpDDQLFAADV 86
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  95 LEAMMVSA-NLKLSEkQEVKkELVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCF 173
Cdd:TIGR01166  87 DQDVAFGPlNLGLSE-AEVE-RRVREALTAVGASGLRERPTHCLSGGEKKRVAIAGAVAMRPDVLLLDEPTAGLDPAGRE 164
                         170       180
                  ....*....|....*....|.
gi 2462526932 174 QVVSLMKSLAQGGRTIICTIH 194
Cdd:TIGR01166 165 QMLAILRRLRAEGMTVVISTH 185
GsiA COG1123
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ...
30-190 5.55e-27

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440740 [Multi-domain]  Cd Length: 514  Bit Score: 114.62  E-value: 5.55e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  30 RRELIGIMGPSGAGKSTFMNILAG-YRESGmkGQILVNGRP------RELRTFRKMSCYIMQD--DMLLPHLTVLEAMMV 100
Cdd:COG1123   290 RGETLGLVGESGSGKSTLARLLLGlLRPTS--GSILFDGKDltklsrRSLRELRRRVQMVFQDpySSLNPRMTVGDIIAE 367
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 101 SA-NLKLSEKQEVKkELVTEILTALGLM-SCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSL 178
Cdd:COG1123   368 PLrLHGLLSRAERR-ERVAELLERVGLPpDLADRYPHELSGGQRQRVAIARALALEPKLLILDEPTSALDVSVQAQILNL 446
                         170
                  ....*....|...
gi 2462526932 179 MKSL-AQGGRTII 190
Cdd:COG1123   447 LRDLqRELGLTYL 459
LivG COG0411
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid ...
30-219 6.30e-27

ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid transport and metabolism];


Pssm-ID: 440180 [Multi-domain]  Cd Length: 257  Bit Score: 109.74  E-value: 6.30e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  30 RRELIGIMGPSGAGKSTFMNILAG-YRESGmkGQILVNGR------PREL------RTFrkmscyimQDDMLLPHLTVLE 96
Cdd:COG0411    29 RGEIVGLIGPNGAGKTTLFNLITGfYRPTS--GRILFDGRditglpPHRIarlgiaRTF--------QNPRLFPELTVLE 98
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  97 AMMVSA-------------NLKLSEKQEVK-KELVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDE 162
Cdd:COG0411    99 NVLVAAharlgrgllaallRLPRARREEREaRERAEELLERVGLADRADEPAGNLSYGQQRRLEIARALATEPKLLLLDE 178
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2462526932 163 PTSGLDSASCFQVVSLMKSLAQG-GRTIICTIHQPSAkLFEMFDKLYILSQGQCIFKG 219
Cdd:COG0411   179 PAAGLNPEETEELAELIRRLRDErGITILLIEHDMDL-VMGLADRIVVLDFGRVIAEG 235
ABC_Carb_Solutes_like cd03259
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ...
32-214 7.06e-27

ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213226 [Multi-domain]  Cd Length: 213  Bit Score: 108.38  E-value: 7.06e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  32 ELIGIMGPSGAGKSTFMNILAGYrESGMKGQILVNGR-----PRELRTFrkmsCYIMQDDMLLPHLTVLEAMMVSANLKL 106
Cdd:cd03259    27 EFLALLGPSGCGKTTLLRLIAGL-ERPDSGEILIDGRdvtgvPPERRNI----GMVFQDYALFPHLTVAENIAFGLKLRG 101
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 107 SEKQEVKKElVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKSL-AQG 185
Cdd:cd03259   102 VPKAEIRAR-VRELLELVGLEGLLNRYPHELSGGQQQRVALARALAREPSLLLLDEPLSALDAKLREELREELKELqREL 180
                         170       180       190
                  ....*....|....*....|....*....|
gi 2462526932 186 GRTIICTIHQPS-AklFEMFDKLYILSQGQ 214
Cdd:cd03259   181 GITTIYVTHDQEeA--LALADRIAVMNEGR 208
FtsE COG2884
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];
36-194 8.80e-27

Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442130 [Multi-domain]  Cd Length: 223  Bit Score: 108.22  E-value: 8.80e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  36 IMGPSGAGKSTFMNILAG-YRESgmKGQILVNG------RPRE---LRtfRKMScYIMQDDMLLPHLTVLEammvsaNLK 105
Cdd:COG2884    33 LTGPSGAGKSTLLKLLYGeERPT--SGQVLVNGqdlsrlKRREipyLR--RRIG-VVFQDFRLLPDRTVYE------NVA 101
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 106 LS------EKQEVKKElVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLM 179
Cdd:COG2884   102 LPlrvtgkSRKEIRRR-VREVLDLVGLSDKAKALPHELSGGEQQRVAIARALVNRPELLLADEPTGNLDPETSWEIMELL 180
                         170
                  ....*....|....*
gi 2462526932 180 KSLAQGGRTIICTIH 194
Cdd:COG2884   181 EEINRRGTTVLIATH 195
ABC_NikE_OppD_transporters cd03257
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ...
30-216 9.24e-27

ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.


Pssm-ID: 213224 [Multi-domain]  Cd Length: 228  Bit Score: 108.36  E-value: 9.24e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  30 RRELIGIMGPSGAGKSTFMNILAGYrESGMKGQILVNGRP------RELRTFRKMSCYIMQDDM--LLPHLTV----LEA 97
Cdd:cd03257    30 KGETLGLVGESGSGKSTLARAILGL-LKPTSGSIIFDGKDllklsrRLRKIRRKEIQMVFQDPMssLNPRMTIgeqiAEP 108
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  98 MMVsanLKLSEKQEVKKELVTEILTALGLmscshTRTAL------LSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSAS 171
Cdd:cd03257   109 LRI---HGKLSKKEARKEAVLLLLVGVGL-----PEEVLnrypheLSGGQRQRVAIARALALNPKLLIADEPTSALDVSV 180
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 2462526932 172 CFQVVSLMKSLAQG-GRTIICTIHQPSAkLFEMFDKLYILSQGQCI 216
Cdd:cd03257   181 QAQILDLLKKLQEElGLTLLFITHDLGV-VAKIADRVAVMYAGKIV 225
glnQ PRK09493
glutamine ABC transporter ATP-binding protein GlnQ;
16-195 1.24e-26

glutamine ABC transporter ATP-binding protein GlnQ;


Pssm-ID: 181906 [Multi-domain]  Cd Length: 240  Bit Score: 108.64  E-value: 1.24e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  16 GYKTLLKCLSGKFCRRELIGIMGPSGAGKSTFM---NILagyrESGMKGQILV-----NGRPRELRTFRKMSCYIMQDDM 87
Cdd:PRK09493   12 GPTQVLHNIDLNIDQGEVVVIIGPSGSGKSTLLrciNKL----EEITSGDLIVdglkvNDPKVDERLIRQEAGMVFQQFY 87
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  88 LLPHLTVLEAMMVSANLKLSEKQEVKKELVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGL 167
Cdd:PRK09493   88 LFPHLTALENVMFGPLRVRGASKEEAEKQARELLAKVGLAERAHHYPSELSGGQQQRVAIARALAVKPKLMLFDEPTSAL 167
                         170       180
                  ....*....|....*....|....*...
gi 2462526932 168 DSASCFQVVSLMKSLAQGGRTIICTIHQ 195
Cdd:PRK09493  168 DPELRHEVLKVMQDLAEEGMTMVIVTHE 195
ThiQ COG3840
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];
32-196 2.01e-26

ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];


Pssm-ID: 443051 [Multi-domain]  Cd Length: 232  Bit Score: 107.53  E-value: 2.01e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  32 ELIGIMGPSGAGKSTFMNILAGYRESgMKGQILVNGR------PRElrtfRKMScYIMQDDMLLPHLTVLE--AMMVSAN 103
Cdd:COG3840    26 ERVAILGPSGAGKSTLLNLIAGFLPP-DSGRILWNGQdltalpPAE----RPVS-MLFQENNLFPHLTVAQniGLGLRPG 99
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 104 LKLSEKQevkKELVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKSLA 183
Cdd:COG3840   100 LKLTAEQ---RAQVEQALERVGLAGLLDRLPGQLSGGQRQRVALARCLVRKRPILLLDEPFSALDPALRQEMLDLVDELC 176
                         170
                  ....*....|....
gi 2462526932 184 QG-GRTIICTIHQP 196
Cdd:COG3840   177 RErGLTVLMVTHDP 190
SunT COG2274
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase ...
32-214 2.57e-26

ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms];


Pssm-ID: 441875 [Multi-domain]  Cd Length: 711  Bit Score: 113.78  E-value: 2.57e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  32 ELIGIMGPSGAGKSTFMNILAG-YRESgmKGQILVNGRPR---ELRTFRKMSCYIMQDDMLLpHLTVLEammvsaNLKLS 107
Cdd:COG2274   502 ERVAIVGRSGSGKSTLLKLLLGlYEPT--SGRILIDGIDLrqiDPASLRRQIGVVLQDVFLF-SGTIRE------NITLG 572
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 108 eKQEVKKELVTEILTALGLMS--CSH---------TRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVV 176
Cdd:COG2274   573 -DPDATDEEIIEAARLAGLHDfiEALpmgydtvvgEGGSNLSGGQRQRLAIARALLRNPRILILDEATSALDAETEAIIL 651
                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 2462526932 177 SLMKSLAQgGRTIICTIHQPSakLFEMFDKLYILSQGQ 214
Cdd:COG2274   652 ENLRRLLK-GRTVIIIAHRLS--TIRLADRIIVLDKGR 686
ABC_Metallic_Cations cd03235
ATP-binding cassette domain of the metal-type transporters; This family includes transporters ...
13-213 6.84e-26

ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.


Pssm-ID: 213202 [Multi-domain]  Cd Length: 213  Bit Score: 105.69  E-value: 6.84e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  13 VASGYKTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAG----YResgmkGQILVNGRPreLRTFRKMSCYIMQD--- 85
Cdd:cd03235     7 VSYGGHPVLEDVSFEVKPGEFLAIVGPNGAGKSTLLKAILGllkpTS-----GSIRVFGKP--LEKERKRIGYVPQRrsi 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  86 DMLLPhLTVLEAMM------VSANLKLSEKQevkKELVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMF 159
Cdd:cd03235    80 DRDFP-ISVRDVVLmglyghKGLFRRLSKAD---KAKVDEALERVGLSELADRQIGELSGGQQQRVLLARALVQDPDLLL 155
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2462526932 160 FDEPTSGLDSASCFQVVSLMKSLAQGGRTIICTIHQPSAkLFEMFDKLYILSQG 213
Cdd:cd03235   156 LDEPFAGVDPKTQEDIYELLRELRREGMTILVVTHDLGL-VLEYFDRVLLLNRT 208
ABC_MetN_methionine_transporter cd03258
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ...
32-225 7.97e-26

ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport. Other members of this system include the MetP permease and the MetQ substrate binding protein. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213225 [Multi-domain]  Cd Length: 233  Bit Score: 106.13  E-value: 7.97e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  32 ELIGIMGPSGAGKSTFMNILAGYrESGMKGQILVNGR------PRELRTFRKMSCYIMQDDMLLPHLTVLEAMMVSANLK 105
Cdd:cd03258    32 EIFGIIGRSGAGKSTLIRCINGL-ERPTSGSVLVDGTdltllsGKELRKARRRIGMIFQHFNLLSSRTVFENVALPLEIA 110
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 106 LSEKQEVKKElVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKSLAQG 185
Cdd:cd03258   111 GVPKAEIEER-VLELLELVGLEDKADAYPAQLSGGQKQRVGIARALANNPKVLLCDEATSALDPETTQSILALLRDINRE 189
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 2462526932 186 -GRTIICTIHQPSAkLFEMFDKLYILSQGQCIFKGVVTNLI 225
Cdd:cd03258   190 lGLTIVLITHEMEV-VKRICDRVAVMEKGEVVEEGTVEEVF 229
CydD COG4988
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease ...
18-225 1.25e-25

ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444012 [Multi-domain]  Cd Length: 563  Bit Score: 111.00  E-value: 1.25e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  18 KTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAGYRESgMKGQILVNGRP-REL--RTFRKMSCYIMQDDMLlPHLTV 94
Cdd:COG4988   350 RPALDGLSLTIPPGERVALVGPSGAGKSTLLNLLLGFLPP-YSGSILINGVDlSDLdpASWRRQIAWVPQNPYL-FAGTI 427
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  95 LEammvsaNLKLSE----KQEVKKEL----VTEILTAL--GLmscsHTRT----ALLSGGQRKRLAIALELVNNPPVMFF 160
Cdd:COG4988   428 RE------NLRLGRpdasDEELEAALeaagLDEFVAALpdGL----DTPLgeggRGLSGGQAQRLALARALLRDAPLLLL 497
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2462526932 161 DEPTSGLDSASCFQVVSLMKSLAQGGRTIICTiHQPSakLFEMFDKLYILSQGQCIFKGVVTNLI 225
Cdd:COG4988   498 DEPTAHLDAETEAEILQALRRLAKGRTVILIT-HRLA--LLAQADRILVLDDGRIVEQGTHEELL 559
ABC_BcrA_bacitracin_resist cd03268
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily ...
16-219 1.36e-25

ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.


Pssm-ID: 213235 [Multi-domain]  Cd Length: 208  Bit Score: 104.61  E-value: 1.36e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  16 GYKTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAG-YRESGmkGQILVNGR--PRELRTFRKMSCyIMQDDMLLPHL 92
Cdd:cd03268    11 GKKRVLDDISLHVKKGEIYGFLGPNGAGKTTTMKIILGlIKPDS--GEITFDGKsyQKNIEALRRIGA-LIEAPGFYPNL 87
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  93 TVLEAMMVSANLKLSEKQEVKkelvtEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASC 172
Cdd:cd03268    88 TARENLRLLARLLGIRKKRID-----EVLDVVGLKDSAKKKVKGFSLGMKQRLGIALALLGNPDLLILDEPTNGLDPDGI 162
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 2462526932 173 FQVVSLMKSLAQGGRTIICTIHQPSaKLFEMFDKLYILSQGQCIFKG 219
Cdd:cd03268   163 KELRELILSLRDQGITVLISSHLLS-EIQKVADRIGIINKGKLIEEG 208
ABC_ModC_molybdenum_transporter cd03297
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type ...
32-219 2.24e-25

ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213264 [Multi-domain]  Cd Length: 214  Bit Score: 104.30  E-value: 2.24e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  32 ELIGIMGPSGAGKSTFMNILAGYrESGMKGQILVNGR------------PRElrtfRKMScYIMQDDMLLPHLTVLEAMM 99
Cdd:cd03297    24 EVTGIFGASGAGKSTLLRCIAGL-EKPDGGTIVLNGTvlfdsrkkinlpPQQ----RKIG-LVFQQYALFPHLNVRENLA 97
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 100 VSANLKlseKQEVKKELVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLM 179
Cdd:cd03297    98 FGLKRK---RNREDRISVDELLDLLGLDHLLNRYPAQLSGGEKQRVALARALAAQPELLLLDEPFSALDRALRLQLLPEL 174
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 2462526932 180 KSLAQ--GGRTIICTiHQPSaKLFEMFDKLYILSQGQCIFKG 219
Cdd:cd03297   175 KQIKKnlNIPVIFVT-HDLS-EAEYLADRIVVMEDGRLQYIG 214
DppF COG1124
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ...
3-214 2.53e-25

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440741 [Multi-domain]  Cd Length: 248  Bit Score: 104.89  E-value: 2.53e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932   3 GFSHAFQKRIVAsgyKTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAGYrESGMKGQILVNGRP---RELRTFRKMS 79
Cdd:COG1124     6 NLSVSYGQGGRR---VPVLKDVSLEVAPGESFGLVGESGSGKSTLLRALAGL-ERPWSGEVTFDGRPvtrRRRKAFRRRV 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  80 CYIMQDDM--LLPHLTVLEAmmVSANLKLSEKQEVKKElVTEILTALGLmscshTRTAL------LSGGQRKRLAIALEL 151
Cdd:COG1124    82 QMVFQDPYasLHPRHTVDRI--LAEPLRIHGLPDREER-IAELLEQVGL-----PPSFLdryphqLSGGQRQRVAIARAL 153
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2462526932 152 VNNPPVMFFDEPTSGLDSASCFQVVSLMKSL-AQGGRTIICTIHQPSAKLFeMFDKLYILSQGQ 214
Cdd:COG1124   154 ILEPELLLLDEPTSALDVSVQAEILNLLKDLrEERGLTYLFVSHDLAVVAH-LCDRVAVMQNGR 216
TauB COG1116
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion ...
5-168 3.29e-25

ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440733 [Multi-domain]  Cd Length: 260  Bit Score: 104.79  E-value: 3.29e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932   5 SHAFQKRivaSGYKTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAGYrESGMKGQILVNGRPRElRTFRKMScYIMQ 84
Cdd:COG1116    14 SKRFPTG---GGGVTALDDVSLTVAAGEFVALVGPSGCGKSTLLRLIAGL-EKPTSGEVLVDGKPVT-GPGPDRG-VVFQ 87
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  85 DDMLLPHLTVLEAMMVSANLKLSEKQEvKKELVTEILTALGLmscSHTRTAL---LSGGQRKRLAIALELVNNPPVMFFD 161
Cdd:COG1116    88 EPALLPWLTVLDNVALGLELRGVPKAE-RRERARELLELVGL---AGFEDAYphqLSGGMRQRVAIARALANDPEVLLMD 163

                  ....*..
gi 2462526932 162 EPTSGLD 168
Cdd:COG1116   164 EPFGALD 170
thiQ TIGR01277
thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ...
17-214 9.31e-25

thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ATPase subunit ThiQ of the ThiBPQ thiamine (and thiamine pyrophosphate) ABC transporter in several Proteobacteria. This protein is found so far only in Proteobacteria, and is found in complete genomes only if the ThiB and ThiP subunits are also found. [Transport and binding proteins, Other]


Pssm-ID: 130344 [Multi-domain]  Cd Length: 213  Bit Score: 102.25  E-value: 9.31e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  17 YKTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAGYRESgMKGQILVNGRPR-ELRTFRKMSCYIMQDDMLLPHLTVL 95
Cdd:TIGR01277  10 YEHLPMEFDLNVADGEIVAIMGPSGAGKSTLLNLIAGFIEP-ASGSIKVNDQSHtGLAPYQRPVSMLFQENNLFAHLTVR 88
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  96 E--AMMVSANLKLSEKQevkKELVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCF 173
Cdd:TIGR01277  89 QniGLGLHPGLKLNAEQ---QEKVVDAAQQVGIADYLDRLPEQLSGGQRQRVALARCLVRPNPILLLDEPFSALDPLLRE 165
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 2462526932 174 QVVSLMKSLA-QGGRTIICTIHQPSaKLFEMFDKLYILSQGQ 214
Cdd:TIGR01277 166 EMLALVKQLCsERQRTLLMVTHHLS-DARAIASQIAVVSQGK 206
ABC_DrrA cd03265
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein ...
30-224 1.72e-24

Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213232 [Multi-domain]  Cd Length: 220  Bit Score: 101.68  E-value: 1.72e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  30 RRELIGIMGPSGAGKSTFMNILAGY-RESGmkGQILVNGRP--RELRTFRKMSCYIMQDDMLLPHLTVLEAMMVSANLKl 106
Cdd:cd03265    25 RGEIFGLLGPNGAGKTTTIKMLTTLlKPTS--GRATVAGHDvvREPREVRRRIGIVFQDLSVDDELTGWENLYIHARLY- 101
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 107 SEKQEVKKELVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKSL-AQG 185
Cdd:cd03265   102 GVPGAERRERIDELLDFVGLLEAADRLVKTYSGGMRRRLEIARSLVHRPEVLFLDEPTIGLDPQTRAHVWEYIEKLkEEF 181
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 2462526932 186 GRTIICTIH-QPSAKlfEMFDKLYILSQGQCIFKGVVTNL 224
Cdd:cd03265   182 GMTILLTTHyMEEAE--QLCDRVAIIDHGRIIAEGTPEEL 219
cbiO PRK13639
cobalt transporter ATP-binding subunit; Provisional
21-219 1.99e-24

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184199 [Multi-domain]  Cd Length: 275  Bit Score: 103.23  E-value: 1.99e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  21 LKCLSGKFCRRELIGIMGPSGAGKST-FMNILAGYRESgmKGQILVNGRP-----RELRTFRKMSCYIMQ--DDMLL-Ph 91
Cdd:PRK13639   18 LKGINFKAEKGEMVALLGPNGAGKSTlFLHFNGILKPT--SGEVLIKGEPikydkKSLLEVRKTVGIVFQnpDDQLFaP- 94
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  92 lTVLEAMMVSA-NLKLSeKQEVKKElVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSA 170
Cdd:PRK13639   95 -TVEEDVAFGPlNLGLS-KEEVEKR-VKEALKAVGMEGFENKPPHHLSGGQKKRVAIAGILAMKPEIIVLDEPTSGLDPM 171
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 2462526932 171 SCFQVVSLMKSLAQGGRTIICTIHQpsAKLFEMF-DKLYILSQGQCIFKG 219
Cdd:PRK13639  172 GASQIMKLLYDLNKEGITIIISTHD--VDLVPVYaDKVYVMSDGKIIKEG 219
GlnQ COG1126
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and ...
32-203 2.00e-24

ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 440743 [Multi-domain]  Cd Length: 239  Bit Score: 101.99  E-value: 2.00e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  32 ELIGIMGPSGAGKSTF---MNILagyrESGMKGQILVNGRP-----RELRTFRKMSCYIMQDDMLLPHLTVLE----AMM 99
Cdd:COG1126    28 EVVVIIGPSGSGKSTLlrcINLL----EEPDSGTITVDGEDltdskKDINKLRRKVGMVFQQFNLFPHLTVLEnvtlAPI 103
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 100 VSanLKLSeKQEVKkELVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLM 179
Cdd:COG1126   104 KV--KKMS-KAEAE-ERAMELLERVGLADKADAYPAQLSGGQQQRVAIARALAMEPKVMLFDEPTSALDPELVGEVLDVM 179
                         170       180
                  ....*....|....*....|....
gi 2462526932 180 KSLAQGGRTIICTIHqpsaklfEM 203
Cdd:COG1126   180 RDLAKEGMTMVVVTH-------EM 196
GsiA COG1123
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ...
14-219 3.76e-24

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440740 [Multi-domain]  Cd Length: 514  Bit Score: 106.14  E-value: 3.76e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  14 ASGYKTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAGY--RESGMKGQILVNGR-----PRELRtfRKMSCYIMQDD 86
Cdd:COG1123    15 PGGDVPAVDGVSLTIAPGETVALVGESGSGKSTLALALMGLlpHGGRISGEVLLDGRdllelSEALR--GRRIGMVFQDP 92
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  87 M--LLPhLTVLEAMM-VSANLKLSEKQevKKELVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEP 163
Cdd:COG1123    93 MtqLNP-VTVGDQIAeALENLGLSRAE--ARARVLELLEAVGLERRLDRYPHQLSGGQRQRVAIAMALALDPDLLIADEP 169
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2462526932 164 TSGLDSASCFQVVSLMKSL-AQGGRTIICTIHQPsAKLFEMFDKLYILSQGQCIFKG 219
Cdd:COG1123   170 TTALDVTTQAEILDLLRELqRERGTTVLLITHDL-GVVAEIADRVVVMDDGRIVEDG 225
ABC_PotA_N cd03300
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ...
32-168 4.32e-24

ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213267 [Multi-domain]  Cd Length: 232  Bit Score: 101.16  E-value: 4.32e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  32 ELIGIMGPSGAGKSTFMNILAGYrESGMKGQILVNGRP-RELRTFRKMSCYIMQDDMLLPHLTVLEAMMVSANLKLSEKQ 110
Cdd:cd03300    27 EFFTLLGPSGCGKTTLLRLIAGF-ETPTSGEILLDGKDiTNLPPHKRPVNTVFQNYALFPHLTVFENIAFGLRLKKLPKA 105
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2462526932 111 EVKKElVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLD 168
Cdd:cd03300   106 EIKER-VAEALDLVQLEGYANRKPSQLSGGQQQRVAIARALVNEPKVLLLDEPLGALD 162
CydC COG4987
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease ...
32-219 4.94e-24

ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444011 [Multi-domain]  Cd Length: 569  Bit Score: 106.00  E-value: 4.94e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  32 ELIGIMGPSGAGKSTFMNILAGYRESgMKGQILVNGRP-RELR--TFRKMSCYIMQDdmllPHL---TVLEammvsaNLK 105
Cdd:COG4987   362 ERVAIVGPSGSGKSTLLALLLRFLDP-QSGSITLGGVDlRDLDedDLRRRIAVVPQR----PHLfdtTLRE------NLR 430
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 106 LSeKQEVKKELVTEILTALGL--MSCS-----HTRT----ALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQ 174
Cdd:COG4987   431 LA-RPDATDEELWAALERVGLgdWLAAlpdglDTWLgeggRRLSGGERRRLALARALLRDAPILLLDEPTEGLDAATEQA 509
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 2462526932 175 VVSLMKSLAQgGRTIICTIHQPSAklFEMFDKLYILSQGQCIFKG 219
Cdd:COG4987   510 LLADLLEALA-GRTVLLITHRLAG--LERMDRILVLEDGRIVEQG 551
ABCC_bacteriocin_exporters cd03245
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic ...
32-219 5.07e-24

ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic bacteriocins of lactic acid bacteria are produced as precursors which have N-terminal leader peptides that share similarities in amino acid sequence and contain a conserved processing site of two glycine residues in positions -1 and -2. A dedicated ATP-binding cassette (ABC) transporter is responsible for the proteolytic cleavage of the leader peptides and subsequent translocation of the bacteriocins across the cytoplasmic membrane.


Pssm-ID: 213212 [Multi-domain]  Cd Length: 220  Bit Score: 100.36  E-value: 5.07e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  32 ELIGIMGPSGAGKSTFMNILAGYRESgMKGQILVNG------RPRELRtfRKMScYIMQDdmllPHL---TVLEammvsa 102
Cdd:cd03245    31 EKVAIIGRVGSGKSTLLKLLAGLYKP-TSGSVLLDGtdirqlDPADLR--RNIG-YVPQD----VTLfygTLRD------ 96
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 103 NLKLSeKQEVKKELVTEILTALGLMSCSHT-----------RTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSAS 171
Cdd:cd03245    97 NITLG-APLADDERILRAAELAGVTDFVNKhpngldlqigeRGRGLSGGQRQAVALARALLNDPPILLLDEPTSAMDMNS 175
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 2462526932 172 CFQVVSLMKSLAqGGRTIICTIHQPSakLFEMFDKLYILSQGQCIFKG 219
Cdd:cd03245   176 EERLKERLRQLL-GDKTLIIITHRPS--LLDLVDRIIVMDSGRIVADG 220
PRK10535 PRK10535
macrolide ABC transporter ATP-binding protein/permease MacB;
32-196 1.20e-23

macrolide ABC transporter ATP-binding protein/permease MacB;


Pssm-ID: 182528 [Multi-domain]  Cd Length: 648  Bit Score: 105.19  E-value: 1.20e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  32 ELIGIMGPSGAGKSTFMNIL-------AG-YRESGMKGQILVNGRPRELRtfRKMSCYIMQDDMLLPHLTVLEAMMVSAN 103
Cdd:PRK10535   35 EMVAIVGASGSGKSTLMNILgcldkptSGtYRVAGQDVATLDADALAQLR--REHFGFIFQRYHLLSHLTAAQNVEVPAV 112
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 104 LKLSEKQEvKKELVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKSLA 183
Cdd:PRK10535  113 YAGLERKQ-RLLRAQELLQRLGLEDRVEYQPSQLSGGQQQRVSIARALMNGGQVILADEPTGALDSHSGEEVMAILHQLR 191
                         170
                  ....*....|...
gi 2462526932 184 QGGRTIICTIHQP 196
Cdd:PRK10535  192 DRGHTVIIVTHDP 204
ABC_putative_ATPase cd03269
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the ...
16-219 2.29e-23

ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the subfamily A transporters involved in drug resistance, nodulation, lipid transport, and bacteriocin and lantibiotic immunity. In eubacteria and archaea, the typical organization consists of one ABC and one or two integral membranes. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213236 [Multi-domain]  Cd Length: 210  Bit Score: 98.12  E-value: 2.29e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  16 GYKTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAGYRESGmKGQILVNGRPRELRTFRKMScYIMQDDMLLPHLTVL 95
Cdd:cd03269    11 GRVTALDDISFSVEKGEIFGLLGPNGAGKTTTIRMILGIILPD-SGEVLFDGKPLDIAARNRIG-YLPEERGLYPKMKVI 88
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  96 EAMMVSANLKLSEKQEVKKElVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQV 175
Cdd:cd03269    89 DQLVYLAQLKGLKKEEARRR-IDEWLERLELSEYANKRVEELSKGNQQKVQFIAAVIHDPELLILDEPFSGLDPVNVELL 167
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 2462526932 176 VSLMKSLAQGGRTIICTIHQpSAKLFEMFDKLYILSQGQCIFKG 219
Cdd:cd03269   168 KDVIRELARAGKTVILSTHQ-MELVEELCDRVLLLNKGRAVLYG 210
ABC_TM1139_LivF_branched cd03224
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of ...
30-219 3.63e-23

ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.


Pssm-ID: 213191 [Multi-domain]  Cd Length: 222  Bit Score: 97.89  E-value: 3.63e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  30 RRELIGIMGPSGAGKSTFMNILAGYRESgMKGQILVNGRP-RELRTFRKMS---CYIMQDDMLLPHLTVLEAMMVSANLK 105
Cdd:cd03224    25 EGEIVALLGRNGAGKTTLLKTIMGLLPP-RSGSIRFDGRDiTGLPPHERARagiGYVPEGRRIFPELTVEENLLLGAYAR 103
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 106 LSEKQEVKKELVTEILTALGLMScsHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKSLAQG 185
Cdd:cd03224   104 RRAKRKARLERVYELFPRLKERR--KQLAGTLSGGEQQMLAIARALMSRPKLLLLDEPSEGLAPKIVEEIFEAIRELRDE 181
                         170       180       190
                  ....*....|....*....|....*....|....
gi 2462526932 186 GRTIIcTIHQPSAKLFEMFDKLYILSQGQCIFKG 219
Cdd:cd03224   182 GVTIL-LVEQNARFALEIADRAYVLERGRVVLEG 214
PRK11264 PRK11264
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional
32-213 4.87e-23

putative amino-acid ABC transporter ATP-binding protein YecC; Provisional


Pssm-ID: 183063 [Multi-domain]  Cd Length: 250  Bit Score: 98.28  E-value: 4.87e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  32 ELIGIMGPSGAGKSTF---MNILagyrESGMKGQILV-----------NGRPRELRTFRKMSCYIMQDDMLLPHLTVLEA 97
Cdd:PRK11264   30 EVVAIIGPSGSGKTTLlrcINLL----EQPEAGTIRVgditidtarslSQQKGLIRQLRQHVGFVFQNFNLFPHRTVLEN 105
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  98 MMVSANLKLSEKQEVKKELVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVS 177
Cdd:PRK11264  106 IIEGPVIVKGEPKEEATARARELLAKVGLAGKETSYPRRLSGGQQQRVAIARALAMRPEVILFDEPTSALDPELVGEVLN 185
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 2462526932 178 LMKSLAQGGRTIICTIHQPS-----AKLFEMFDKLYILSQG 213
Cdd:PRK11264  186 TIRQLAQEKRTMVIVTHEMSfardvADRAIFMDQGRIVEQG 226
ArtP COG4161
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];
21-195 5.80e-23

ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443326 [Multi-domain]  Cd Length: 242  Bit Score: 98.16  E-value: 5.80e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  21 LKCLSGkfcrrELIGIMGPSGAGKSTF---MNILagyrESGMKGQILVNGR---------PRELRTFRKMSCYIMQDDML 88
Cdd:COG4161    23 LECPSG-----ETLVLLGPSGAGKSSLlrvLNLL----ETPDSGQLNIAGHqfdfsqkpsEKAIRLLRQKVGMVFQQYNL 93
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  89 LPHLTVLEAMmVSAN---LKLSEKQEVKKelVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTS 165
Cdd:COG4161    94 WPHLTVMENL-IEAPckvLGLSKEQAREK--AMKLLARLRLTDKADRFPLHLSGGQQQRVAIARALMMEPQVLLFDEPTA 170
                         170       180       190
                  ....*....|....*....|....*....|
gi 2462526932 166 GLDSASCFQVVSLMKSLAQGGRTIICTIHQ 195
Cdd:COG4161   171 ALDPEITAQVVEIIRELSQTGITQVIVTHE 200
ABC_ModC_like cd03299
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely ...
21-180 1.45e-22

ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely related to ModC. ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213266 [Multi-domain]  Cd Length: 235  Bit Score: 96.64  E-value: 1.45e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  21 LKCLSGKFCRRELIGIMGPSGAGKSTFMNILAGYRESGmKGQILVNGR-----PRELRTFrkmsCYIMQDDMLLPHLTVL 95
Cdd:cd03299    15 LKNVSLEVERGDYFVILGPTGSGKSVLLETIAGFIKPD-SGKILLNGKditnlPPEKRDI----SYVPQNYALFPHMTVY 89
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  96 EAMMVSANLKLSEKQEVKKElVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQV 175
Cdd:cd03299    90 KNIAYGLKKRKVDKKEIERK-VLEIAEMLGIDHLLNRKPETLSGGEQQRVAIARALVVNPKILLLDEPFSALDVRTKEKL 168

                  ....*
gi 2462526932 176 VSLMK 180
Cdd:cd03299   169 REELK 173
YbbA COG4181
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase ...
30-197 2.58e-22

Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443338 [Multi-domain]  Cd Length: 233  Bit Score: 95.96  E-value: 2.58e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  30 RRELIGIMGPSGAGKSTFMNILAGYrESGMKGQILVNGRP------RELRTFRKMSC-YIMQDDMLLPHLTVLEAMMVSA 102
Cdd:COG4181    37 AGESVAIVGASGSGKSTLLGLLAGL-DRPTSGTVRLAGQDlfaldeDARARLRARHVgFVFQSFQLLPTLTALENVMLPL 115
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 103 NLKlSEKQevKKELVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKSL 182
Cdd:COG4181   116 ELA-GRRD--ARARARALLERVGLGHRLDHYPAQLSGGEQQRVALARAFATEPAILFADEPTGNLDAATGEQIIDLLFEL 192
                         170
                  ....*....|....*.
gi 2462526932 183 -AQGGRTIICTIHQPS 197
Cdd:COG4181   193 nRERGTTLVLVTHDPA 208
ABC_MalK_N cd03301
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) ...
16-214 7.04e-22

The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) proteins function from bacteria to human, mediating the translocation of substances into and out of cells or organelles. ABC transporters contain two transmembrane-spanning domains (TMDs) or subunits and two nucleotide binding domains (NBDs) or subunits that couple transport to the hydrolysis of ATP. In the maltose transport system, the periplasmic maltose binding protein (MBP) stimulates the ATPase activity of the membrane-associated transporter, which consists of two transmembrane subunits, MalF and MalG, and two copies of the ATP binding subunit, MalK, and becomes tightly bound to the transporter in the catalytic transition state, ensuring that maltose is passed to the transporter as ATP is hydrolyzed.


Pssm-ID: 213268 [Multi-domain]  Cd Length: 213  Bit Score: 94.24  E-value: 7.04e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  16 GYKTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAGYrESGMKGQILVNGR------PRElrtfRKMScYIMQDDMLL 89
Cdd:cd03301    11 GNVTALDDLNLDIADGEFVVLLGPSGCGKTTTLRMIAGL-EEPTSGRIYIGGRdvtdlpPKD----RDIA-MVFQNYALY 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  90 PHLTVLEAMMVSANLKLSEKQEVKKElVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDS 169
Cdd:cd03301    85 PHMTVYDNIAFGLKLRKVPKDEIDER-VREVAELLQIEHLLDRKPKQLSGGQRQRVALGRAIVREPKVFLMDEPLSNLDA 163
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 2462526932 170 ASCFQVVSLMKSLAQG-GRTIICTIH-QPSAklFEMFDKLYILSQGQ 214
Cdd:cd03301   164 KLRVQMRAELKRLQQRlGTTTIYVTHdQVEA--MTMADRIAVMNDGQ 208
PRK09984 PRK09984
phosphonate ABC transporter ATP-binding protein;
32-219 9.54e-22

phosphonate ABC transporter ATP-binding protein;


Pssm-ID: 182182 [Multi-domain]  Cd Length: 262  Bit Score: 95.08  E-value: 9.54e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  32 ELIGIMGPSGAGKSTFMNILAGY----RESGMKGQILVN-----GR-PRELRTFRKMSCYIMQDDMLLPHLTVLEAMMVS 101
Cdd:PRK09984   31 EMVALLGPSGSGKSTLLRHLSGLitgdKSAGSHIELLGRtvqreGRlARDIRKSRANTGYIFQQFNLVNRLSVLENVLIG 110
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 102 A-------NLKLSEKQEVKKELVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQ 174
Cdd:PRK09984  111 AlgstpfwRTCFSWFTREQKQRALQALTRVGMVHFAHQRVSTLSGGQQQRVAIARALMQQAKVILADEPIASLDPESARI 190
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 2462526932 175 VVSLMKSLAQG-GRTIICTIHQPSAKLfEMFDKLYILSQGQCIFKG 219
Cdd:PRK09984  191 VMDTLRDINQNdGITVVVTLHQVDYAL-RYCERIVALRQGHVFYDG 235
PotA COG3842
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ...
32-168 9.84e-22

ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443052 [Multi-domain]  Cd Length: 353  Bit Score: 96.71  E-value: 9.84e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  32 ELIGIMGPSGAGKSTFMNILAGYrESGMKGQILVNGR------PRElrtfRKMScYIMQDDMLLPHLTVLEammvsaN-- 103
Cdd:COG3842    32 EFVALLGPSGCGKTTLLRMIAGF-ETPDSGRILLDGRdvtglpPEK----RNVG-MVFQDYALFPHLTVAE------Nva 99
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2462526932 104 --LKLS--EKQEVkKELVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLD 168
Cdd:COG3842   100 fgLRMRgvPKAEI-RARVAELLELVGLEGLADRYPHQLSGGQQQRVALARALAPEPRVLLLDEPLSALD 167
ABCC_Protease_Secretion cd03246
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of ...
32-214 1.10e-21

ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of the protease secretion system PrtD, a 60-kDa integral membrane protein sharing 37% identity with HlyB, the ABC component of the alpha-hemolysin secretion pathway, in the C-terminal domain. They export degradative enzymes by using a type I protein secretion system and lack an N-terminal signal peptide, but contain a C-terminal secretion signal. The Type I secretion apparatus is made up of three components, an ABC transporter, a membrane fusion protein (MFP), and an outer membrane protein (OMP). For the HlyA transporter complex, HlyB (ABC transporter) and HlyD (MFP) reside in the inner membrane of E. coli. The OMP component is TolC, which is thought to interact with the MFP to form a continuous channel across the periplasm from the cytoplasm to the exterior. HlyB belongs to the family of ABC transporters, which are ubiquitous, ATP-dependent transmembrane pumps or channels. The spectrum of transport substrates ranges from inorganic ions, nutrients such as amino acids, sugars, or peptides, hydrophobic drugs, to large polypeptides, such as HlyA.


Pssm-ID: 213213 [Multi-domain]  Cd Length: 173  Bit Score: 92.28  E-value: 1.10e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  32 ELIGIMGPSGAGKSTFMNILAGYRESGmKGQILVNGRPRE---LRTFRKMSCYIMQDDMLLPHlTVLEAmmvsanlklse 108
Cdd:cd03246    29 ESLAIIGPSGSGKSTLARLILGLLRPT-SGRVRLDGADISqwdPNELGDHVGYLPQDDELFSG-SIAEN----------- 95
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 109 kqevkkelvteiltalglmscshtrtaLLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKSLAQGGRT 188
Cdd:cd03246    96 ---------------------------ILSGGQRQRLGLARALYGNPRILVLDEPNSHLDVEGERALNQAIAALKAAGAT 148
                         170       180
                  ....*....|....*....|....*.
gi 2462526932 189 IICTIHQPSakLFEMFDKLYILSQGQ 214
Cdd:cd03246   149 RIVIAHRPE--TLASADRILVLEDGR 172
CysA COG1118
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and ...
32-169 1.40e-21

ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440735 [Multi-domain]  Cd Length: 348  Bit Score: 96.37  E-value: 1.40e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  32 ELIGIMGPSGAGKSTFMNILAGYrESGMKGQILVNGR-------PRElrtfRKMScYIMQDDMLLPHLTVLEammvsaN- 103
Cdd:COG1118    29 ELVALLGPSGSGKTTLLRIIAGL-ETPDSGRIVLNGRdlftnlpPRE----RRVG-FVFQHYALFPHMTVAE------Ni 96
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462526932 104 ------LKLSEKQevKKELVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDS 169
Cdd:COG1118    97 afglrvRPPSKAE--IRARVEELLELVQLEGLADRYPSQLSGGQRQRVALARALAVEPEVLLLDEPFGALDA 166
thiQ PRK10771
thiamine ABC transporter ATP-binding protein ThiQ;
32-170 1.69e-21

thiamine ABC transporter ATP-binding protein ThiQ;


Pssm-ID: 182716 [Multi-domain]  Cd Length: 232  Bit Score: 93.49  E-value: 1.69e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  32 ELIGIMGPSGAGKSTFMNILAGYRESGmKGQILVNG----------RPRELrtfrkmscyIMQDDMLLPHLTVLE--AMM 99
Cdd:PRK10771   26 ERVAILGPSGAGKSTLLNLIAGFLTPA-SGSLTLNGqdhtttppsrRPVSM---------LFQENNLFSHLTVAQniGLG 95
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462526932 100 VSANLKLSEKQevkKELVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSA 170
Cdd:PRK10771   96 LNPGLKLNAAQ---REKLHAIARQMGIEDLLARLPGQLSGGQRQRVALARCLVREQPILLLDEPFSALDPA 163
CydD TIGR02857
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family ...
31-197 1.82e-21

thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD


Pssm-ID: 274323 [Multi-domain]  Cd Length: 529  Bit Score: 98.13  E-value: 1.82e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  31 RELIGIMGPSGAGKSTFMNILAGYRESGmKGQILVNGRPR---ELRTFRKMSCYIMQddmlLPHLTvleAMMVSANLKLS 107
Cdd:TIGR02857 348 GERVALVGPSGAGKSTLLNLLLGFVDPT-EGSIAVNGVPLadaDADSWRDQIAWVPQ----HPFLF---AGTIAENIRLA 419
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 108 EKqEVKKELVTEILTALGLMSCS-------HT----RTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVV 176
Cdd:TIGR02857 420 RP-DASDAEIREALERAGLDEFVaalpqglDTpigeGGAGLSGGQAQRLALARAFLRDAPLLLLDEPTAHLDAETEAEVL 498
                         170       180
                  ....*....|....*....|.
gi 2462526932 177 SLMKSLAQgGRTIICTIHQPS 197
Cdd:TIGR02857 499 EALRALAQ-GRTVLLVTHRLA 518
artP PRK11124
arginine transporter ATP-binding subunit; Provisional
21-195 2.01e-21

arginine transporter ATP-binding subunit; Provisional


Pssm-ID: 182980 [Multi-domain]  Cd Length: 242  Bit Score: 93.54  E-value: 2.01e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  21 LKCLSGkfcrrELIGIMGPSGAGKSTFMNILaGYRESGMKGQILVNGR---------PRELRTFRKMSCYIMQDDMLLPH 91
Cdd:PRK11124   23 LDCPQG-----ETLVLLGPSGAGKSSLLRVL-NLLEMPRSGTLNIAGNhfdfsktpsDKAIRELRRNVGMVFQQYNLWPH 96
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  92 LTVLE-----AMMVsanLKLSEKQEVKKELvtEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSG 166
Cdd:PRK11124   97 LTVQQnlieaPCRV---LGLSKDQALARAE--KLLERLRLKPYADRFPLHLSGGQQQRVAIARALMMEPQVLLFDEPTAA 171
                         170       180
                  ....*....|....*....|....*....
gi 2462526932 167 LDSASCFQVVSLMKSLAQGGRTIICTIHQ 195
Cdd:PRK11124  172 LDPEITAQIVSIIRELAETGITQVIVTHE 200
ABC_PstB_phosphate_transporter cd03260
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of ...
13-194 2.31e-21

ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD).


Pssm-ID: 213227 [Multi-domain]  Cd Length: 227  Bit Score: 93.01  E-value: 2.31e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  13 VASGYKTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAGYRESGMK----GQILVNGR--------PRELRTFRKMsc 80
Cdd:cd03260     8 VYYGDKHALKDISLDIPKGEITALIGPSGCGKSTLLRLLNRLNDLIPGapdeGEVLLDGKdiydldvdVLELRRRVGM-- 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  81 yIMQDDMLLPhLTVLEAMMVSANLKLSEKQEVKKELVTEILTALGLMSCSHTRTAL--LSGGQRKRLAIALELVNNPPVM 158
Cdd:cd03260    86 -VFQKPNPFP-GSIYDNVAYGLRLHGIKLKEELDERVEEALRKAALWDEVKDRLHAlgLSGGQQQRLCLARALANEPEVL 163
                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 2462526932 159 FFDEPTSGLDSASCFQVVSLMKSLAQgGRTIICTIH 194
Cdd:cd03260   164 LLDEPTSALDPISTAKIEELIAELKK-EYTIVIVTH 198
drrA TIGR01188
daunorubicin resistance ABC transporter ATP-binding subunit; This model describes daunorubicin ...
30-224 2.62e-21

daunorubicin resistance ABC transporter ATP-binding subunit; This model describes daunorubicin resistance ABC transporter, ATP binding subunit in bacteria and archaea. This model is restricted in its scope to preferentially recognize the ATP binding subunit associated with effux of the drug, daunorubicin. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. In eukaryotes proteins of similar function include p-gyco proteins, multidrug resistance protein etc. [Transport and binding proteins, Other]


Pssm-ID: 130256 [Multi-domain]  Cd Length: 302  Bit Score: 94.76  E-value: 2.62e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  30 RRELIGIMGPSGAGKSTFMNILAGY-RESGmkGQILVNG-----RPRELR-----TFRKMSCYimqDDmllphLTVLEAM 98
Cdd:TIGR01188  18 EGEVFGFLGPNGAGKTTTIRMLTTLlRPTS--GTARVAGydvvrEPRKVRrsigiVPQYASVD---ED-----LTGRENL 87
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  99 MVSANLK-LSEKqeVKKELVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVS 177
Cdd:TIGR01188  88 EMMGRLYgLPKD--EAEERAEELLELFELGEAADRPVGTYSGGMRRRLDIAASLIHQPDVLFLDEPTTGLDPRTRRAIWD 165
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 2462526932 178 LMKSLAQGGRTIICTIHQpsakLFE---MFDKLYILSQGQCIFKGVVTNL 224
Cdd:TIGR01188 166 YIRALKEEGVTILLTTHY----MEEadkLCDRIAIIDHGRIIAEGTPEEL 211
ABC_YhbG cd03218
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the ...
9-225 4.39e-21

ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.


Pssm-ID: 213185 [Multi-domain]  Cd Length: 232  Bit Score: 92.22  E-value: 4.39e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932   9 QKRIvasGYKTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAGYrESGMKGQILVNGR-----PRELRTfRKMSCYIM 83
Cdd:cd03218     7 SKRY---GKRKVVNGVSLSVKQGEIVGLLGPNGAGKTTTFYMIVGL-VKPDSGKILLDGQditklPMHKRA-RLGIGYLP 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  84 QDDMLLPHLTVLEAMMVSANLKLSEKQEVKKELVtEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEP 163
Cdd:cd03218    82 QEASIFRKLTVEENILAVLEIRGLSKKEREEKLE-ELLEEFHITHLRKSKASSLSGGERRRVEIARALATNPKFLLLDEP 160
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462526932 164 TSGLDSASCFQVVSLMKSLAQGGRTIICTIHQPSAKLfEMFDKLYILSQGQCIFKGVVTNLI 225
Cdd:cd03218   161 FAGVDPIAVQDIQKIIKILKDRGIGVLITDHNVRETL-SITDRAYIIYEGKVLAEGTPEEIA 221
PRK13536 PRK13536
nodulation factor ABC transporter ATP-binding protein NodI;
3-225 6.17e-21

nodulation factor ABC transporter ATP-binding protein NodI;


Pssm-ID: 237419 [Multi-domain]  Cd Length: 340  Bit Score: 94.13  E-value: 6.17e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932   3 GFSHAFQKRIVASGyktllkcLSGKFCRRELIGIMGPSGAGKSTFMNILAGYRESGmKGQILVNGR--PRELRTFRKMSC 80
Cdd:PRK13536   46 GVSKSYGDKAVVNG-------LSFTVASGECFGLLGPNGAGKSTIARMILGMTSPD-AGKITVLGVpvPARARLARARIG 117
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  81 YIMQDDMLLPHLTVLEAMMVSANLKLSEKQEVKkELVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFF 160
Cdd:PRK13536  118 VVPQFDNLDLEFTVRENLLVFGRYFGMSTREIE-AVIPSLLEFARLESKADARVSDLSGGMKRRLTLARALINDPQLLIL 196
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2462526932 161 DEPTSGLDSASCFQVVSLMKSLAQGGRTIICTIH--QPSAKLfemFDKLYILSQGQCIFKGVVTNLI 225
Cdd:PRK13536  197 DEPTTGLDPHARHLIWERLRSLLARGKTILLTTHfmEEAERL---CDRLCVLEAGRKIAEGRPHALI 260
lolD PRK11629
lipoprotein-releasing ABC transporter ATP-binding protein LolD;
20-192 7.08e-21

lipoprotein-releasing ABC transporter ATP-binding protein LolD;


Pssm-ID: 183244 [Multi-domain]  Cd Length: 233  Bit Score: 91.80  E-value: 7.08e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  20 LLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAGYrESGMKGQILVNGRP---------RELRTfRKMScYIMQDDMLLP 90
Cdd:PRK11629   24 VLHNVSFSIGEGEMMAIVGSSGSGKSTLLHLLGGL-DTPTSGDVIFNGQPmsklssaakAELRN-QKLG-FIYQFHHLLP 100
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  91 HLTVLE--AM-MVSANLKLSEKQEVKKELvteiLTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGL 167
Cdd:PRK11629  101 DFTALEnvAMpLLIGKKKPAEINSRALEM----LAAVGLEHRANHRPSELSGGERQRVAIARALVNNPRLVLADEPTGNL 176
                         170       180
                  ....*....|....*....|....*..
gi 2462526932 168 DSASCFQVVSLMKSL--AQGGRTIICT 192
Cdd:PRK11629  177 DARNADSIFQLLGELnrLQGTAFLVVT 203
cbiO PRK13638
energy-coupling factor ABC transporter ATP-binding protein;
20-219 7.59e-21

energy-coupling factor ABC transporter ATP-binding protein;


Pssm-ID: 184198 [Multi-domain]  Cd Length: 271  Bit Score: 92.76  E-value: 7.59e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  20 LLKCLSGKFCRRELIGIMGPSGAGKST-FMNILAGYRESgmKGQILVNGRP-----RELRTFRKMSCYIMQD-DMLLPHL 92
Cdd:PRK13638   16 VLKGLNLDFSLSPVTGLVGANGCGKSTlFMNLSGLLRPQ--KGAVLWQGKPldyskRGLLALRQQVATVFQDpEQQIFYT 93
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  93 TVLEAMMVS-ANLKLSEKQEVKKelVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSAS 171
Cdd:PRK13638   94 DIDSDIAFSlRNLGVPEAEITRR--VDEALTLVDAQHFRHQPIQCLSHGQKKRVAIAGALVLQARYLLLDEPTAGLDPAG 171
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 2462526932 172 CFQVVSLMKSLAQGGRTIICTIHQPSAkLFEMFDKLYILSQGQCIFKG 219
Cdd:PRK13638  172 RTQMIAIIRRIVAQGNHVIISSHDIDL-IYEISDAVYVLRQGQILTHG 218
HisP COG4598
ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism];
32-194 8.72e-21

ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443652 [Multi-domain]  Cd Length: 259  Bit Score: 92.17  E-value: 8.72e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  32 ELIGIMGPSGAGKSTF---MNILagyrESGMKGQILVNGR----------------PRELRTFRKMSCYIMQDDMLLPHL 92
Cdd:COG4598    35 DVISIIGSSGSGKSTFlrcINLL----ETPDSGEIRVGGEeirlkpdrdgelvpadRRQLQRIRTRLGMVFQSFNLWSHM 110
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  93 TVLEAMM-----VsanLKLSeKQEVKkELVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGL 167
Cdd:COG4598   111 TVLENVIeapvhV---LGRP-KAEAI-ERAEALLAKVGLADKRDAYPAHLSGGQQQRAAIARALAMEPEVMLFDEPTSAL 185
                         170       180
                  ....*....|....*....|....*..
gi 2462526932 168 DSASCFQVVSLMKSLAQGGRTIICTIH 194
Cdd:COG4598   186 DPELVGEVLKVMRDLAEEGRTMLVVTH 212
YnjD COG4136
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function ...
18-170 1.03e-20

ABC-type uncharacterized transport system YnjBCD, ATPase component [General function prediction only];


Pssm-ID: 443311 [Multi-domain]  Cd Length: 211  Bit Score: 90.62  E-value: 1.03e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  18 KTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAGYRESG--MKGQILVNGRP-RELRTFRKMSCYIMQDDMLLPHLTV 94
Cdd:COG4136    14 RPLLAPLSLTVAPGEILTLMGPSGSGKSTLLAAIAGTLSPAfsASGEVLLNGRRlTALPAEQRRIGILFQDDLLFPHLSV 93
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2462526932  95 LE--AMMVSANLKLSEKqevkKELVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSA 170
Cdd:COG4136    94 GEnlAFALPPTIGRAQR----RARVEQALEEAGLAGFADRDPATLSGGQRARVALLRALLAEPRALLLDEPFSKLDAA 167
AbcC COG1135
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];
32-225 1.10e-20

ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 440750 [Multi-domain]  Cd Length: 339  Bit Score: 93.60  E-value: 1.10e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  32 ELIGIMGPSGAGKSTF---MNILagyrESGMKGQILVNGR------PRELRTFRK---MscyIMQDDMLLPHLTVLEamm 99
Cdd:COG1135    32 EIFGIIGYSGAGKSTLircINLL----ERPTSGSVLVDGVdltalsERELRAARRkigM---IFQHFNLLSSRTVAE--- 101
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 100 vsaN----LKLS--EKQEVKKElVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCF 173
Cdd:COG1135   102 ---NvalpLEIAgvPKAEIRKR-VAELLELVGLSDKADAYPSQLSGGQKQRVGIARALANNPKVLLCDEATSALDPETTR 177
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2462526932 174 QVVSLMKSL-AQGGRTIICTIHqpsaklfEM------FDKLYILSQGQCIFKGVVTNLI 225
Cdd:COG1135   178 SILDLLKDInRELGLTIVLITH-------EMdvvrriCDRVAVLENGRIVEQGPVLDVF 229
ModF COG1119
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA ...
36-219 1.11e-20

ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA [Inorganic ion transport and metabolism];


Pssm-ID: 440736 [Multi-domain]  Cd Length: 250  Bit Score: 91.68  E-value: 1.11e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  36 IMGPSGAGKSTFMNILAGYRESGMKGQILVNGRPR------ELRTfrkmscYI------MQDDmLLPHLTVLEaMMVSA- 102
Cdd:COG1119    34 ILGPNGAGKSTLLSLITGDLPPTYGNDVRLFGERRggedvwELRK------RIglvspaLQLR-FPRDETVLD-VVLSGf 105
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 103 ------NLKLSEKQEvkkELVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVV 176
Cdd:COG1119   106 fdsiglYREPTDEQR---ERARELLELLGLAHLADRPFGTLSQGEQRRVLIARALVKDPELLILDEPTAGLDLGARELLL 182
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 2462526932 177 SLMKSLAQ-GGRTIICTIHQPSAkLFEMFDKLYILSQGQCIFKG 219
Cdd:COG1119   183 ALLDKLAAeGAPTLVLVTHHVEE-IPPGITHVLLLKDGRVVAAG 225
ABCC_Glucan_exporter_like cd03254
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan ...
32-219 1.23e-20

ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan exporter ATP-binding protein. In A. tumefaciens cyclic beta-1, 2-glucan must be transported into the periplasmic space to exert its action as a virulence factor. This subfamily belongs to the MRP-like family and is involved in drug, peptide, and lipid export. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains each composed of six transmembrane (TM) helices and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213221 [Multi-domain]  Cd Length: 229  Bit Score: 90.75  E-value: 1.23e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  32 ELIGIMGPSGAGKSTFMNILAGYRESgMKGQILVNGRP---RELRTFRKMSCYIMQDDMLLPHlTVLEammvsaNLKLSe 108
Cdd:cd03254    30 ETVAIVGPTGAGKTTLINLLMRFYDP-QKGQILIDGIDirdISRKSLRSMIGVVLQDTFLFSG-TIME------NIRLG- 100
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 109 KQEVKKELVTEILTALGL----MSCSH-------TRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVS 177
Cdd:cd03254   101 RPNATDEEVIEAAKEAGAhdfiMKLPNgydtvlgENGGNLSQGERQLLAIARAMLRDPKILILDEATSNIDTETEKLIQE 180
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 2462526932 178 LMKSLAQgGRTIICTIHQPSAKLFEmfDKLYILSQGQCIFKG 219
Cdd:cd03254   181 ALEKLMK-GRTSIIIAHRLSTIKNA--DKILVLDDGKIIEEG 219
PRK13539 PRK13539
cytochrome c biogenesis protein CcmA; Provisional
32-196 1.78e-20

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 237421 [Multi-domain]  Cd Length: 207  Bit Score: 89.93  E-value: 1.78e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  32 ELIGIMGPSGAGKSTFMNILAGYRESgMKGQILVNGRPRELRTFRKMSCYIMQDDMLLPHLTVLEAMMVSANLKLSEKQE 111
Cdd:PRK13539   29 EALVLTGPNGSGKTTLLRLIAGLLPP-AAGTIKLDGGDIDDPDVAEACHYLGHRNAMKPALTVAENLEFWAAFLGGEELD 107
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 112 VkkelvTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKS-LAQGGRTII 190
Cdd:PRK13539  108 I-----AAALEAVGLAPLAHLPFGYLSAGQKRRVALARLLVSNRPIWILDEPTAALDAAAVALFAELIRAhLAQGGIVIA 182

                  ....*.
gi 2462526932 191 CTiHQP 196
Cdd:PRK13539  183 AT-HIP 187
PRK10619 PRK10619
histidine ABC transporter ATP-binding protein HisP;
16-195 1.79e-20

histidine ABC transporter ATP-binding protein HisP;


Pssm-ID: 182592 [Multi-domain]  Cd Length: 257  Bit Score: 91.18  E-value: 1.79e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  16 GYKTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILaGYRESGMKGQILVNGR----------------PRELRTFRKMS 79
Cdd:PRK10619   16 GEHEVLKGVSLQANAGDVISIIGSSGSGKSTFLRCI-NFLEKPSEGSIVVNGQtinlvrdkdgqlkvadKNQLRLLRTRL 94
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  80 CYIMQDDMLLPHLTVLEAMMVSANLKLSEKQEVKKELVTEILTALGLMSCSHTRTAL-LSGGQRKRLAIALELVNNPPVM 158
Cdd:PRK10619   95 TMVFQHFNLWSHMTVLENVMEAPIQVLGLSKQEARERAVKYLAKVGIDERAQGKYPVhLSGGQQQRVSIARALAMEPEVL 174
                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 2462526932 159 FFDEPTSGLDSASCFQVVSLMKSLAQGGRTIICTIHQ 195
Cdd:PRK10619  175 LFDEPTSALDPELVGEVLRIMQQLAEEGKTMVVVTHE 211
MalK COG3839
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism]; ...
32-168 5.55e-20

ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism];


Pssm-ID: 443050 [Multi-domain]  Cd Length: 352  Bit Score: 91.67  E-value: 5.55e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  32 ELIGIMGPSGAGKSTFMNILAG-YRESGmkGQILVNGR------PRElrtfRKMScyiM--QDDMLLPHLTVLEammvsa 102
Cdd:COG3839    30 EFLVLLGPSGCGKSTLLRMIAGlEDPTS--GEILIGGRdvtdlpPKD----RNIA---MvfQSYALYPHMTVYE------ 94
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462526932 103 N----LKLS--EKQEVKKElVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLD 168
Cdd:COG3839    95 NiafpLKLRkvPKAEIDRR-VREAAELLGLEDLLDRKPKQLSGGQRQRVALGRALVREPKVFLLDEPLSNLD 165
ABC_CcmA_heme_exporter cd03231
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the ...
13-196 8.56e-20

Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the bacterial CcmAB transporter. The CCM family is involved in bacterial cytochrome c biogenesis. Cytochrome c maturation in E. coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperon that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. The CcmAB proteins represent an ABC transporter and the CcmCD proteins participate in heme transfer to CcmE.


Pssm-ID: 213198 [Multi-domain]  Cd Length: 201  Bit Score: 87.93  E-value: 8.56e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  13 VASGYKTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAGYRESgMKGQILVNGRP-RELRTFRKMSC-YIMQDDMLLP 90
Cdd:cd03231     8 CERDGRALFSGLSFTLAAGEALQVTGPNGSGKTTLLRILAGLSPP-LAGRVLLNGGPlDFQRDSIARGLlYLGHAPGIKT 86
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  91 HLTVLEAMMVSANLKLSEKqevkkelVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSA 170
Cdd:cd03231    87 TLSVLENLRFWHADHSDEQ-------VEEALARVGLNGFEDRPVAQLSAGQQRRVALARLLLSGRPLWILDEPTTALDKA 159
                         170       180
                  ....*....|....*....|....*.
gi 2462526932 171 SCFQVVSLMKSLAQGGRTIICTIHQP 196
Cdd:cd03231   160 GVARFAEAMAGHCARGGMVVLTTHQD 185
ccmA TIGR01189
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein ...
12-196 1.34e-19

heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein encoded by ccmA in bacteria. An exception is, an arabidopsis protein. Quite likely this is encoded by an organelle. Bacterial c-type cytocromes are located on the periplasmic side of the cytoplasmic membrane. Several gene products encoded in a locus designated as 'ccm' are implicated in the transport and assembly of the functional cytochrome C. This cluster includes genes: ccmA;B;C;D;E;F;G and H. The posttranslational pathway includes the transport of heme moiety, the secretion of the apoprotein and the covalent attachment of the heme with the apoprotein. The proteins ccmA and B represent an ABC transporter; ccmC and D participate in heme transfer to ccmE, which function as a periplasmic heme chaperone. The presence of ccmF, G and H is suggested to be obligatory for the final functional assembly of cytochrome c. [Protein fate, Protein and peptide secretion and trafficking, Transport and binding proteins, Other]


Pssm-ID: 273491 [Multi-domain]  Cd Length: 198  Bit Score: 87.03  E-value: 1.34e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  12 IVASGYKTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAGYRESgMKGQILVNGRPR-ELRTFRKMSC-YIMQDDMLL 89
Cdd:TIGR01189   7 ACSRGERMLFEGLSFTLNAGEALQVTGPNGIGKTTLLRILAGLLRP-DSGEVRWNGTPLaEQRDEPHENIlYLGHLPGLK 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  90 PHLTVLEAMMVSANLKLSEKQEVKkelvtEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDS 169
Cdd:TIGR01189  86 PELSALENLHFWAAIHGGAQRTIE-----DALAAVGLTGFEDLPAAQLSAGQQRRLALARLWLSRRPLWILDEPTTALDK 160
                         170       180
                  ....*....|....*....|....*...
gi 2462526932 170 ASCFQVVSLMKS-LAQGGRTIICTiHQP 196
Cdd:TIGR01189 161 AGVALLAGLLRAhLARGGIVLLTT-HQD 187
cbiO PRK13636
cobalt transporter ATP-binding subunit; Provisional
30-219 2.65e-19

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184196 [Multi-domain]  Cd Length: 283  Bit Score: 88.37  E-value: 2.65e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  30 RRELIGIMGPSGAGKSTFMNILAGYRESgMKGQILVNGRP-----RELRTFRKMSCYIMQD-DMLLPHLTVLEAMMVSA- 102
Cdd:PRK13636   31 KGEVTAILGGNGAGKSTLFQNLNGILKP-SSGRILFDGKPidysrKGLMKLRESVGMVFQDpDNQLFSASVYQDVSFGAv 109
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 103 NLKLSEKqEVKKElVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKSL 182
Cdd:PRK13636  110 NLKLPED-EVRKR-VDNALKRTGIEHLKDKPTHCLSFGQKKRVAIAGVLVMEPKVLVLDEPTAGLDPMGVSEIMKLLVEM 187
                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 2462526932 183 AQG-GRTIICTIHQ-PSAKLFemFDKLYILSQGQCIFKG 219
Cdd:PRK13636  188 QKElGLTIIIATHDiDIVPLY--CDNVFVMKEGRVILQG 224
type_I_sec_LssB TIGR03375
type I secretion system ATPase, LssB family; Type I protein secretion is a system in some ...
32-219 3.79e-19

type I secretion system ATPase, LssB family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. This model is related to models TIGR01842 and TIGR01846, and to bacteriocin ABC transporters that cleave their substrates during export. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis]


Pssm-ID: 274550 [Multi-domain]  Cd Length: 694  Bit Score: 91.47  E-value: 3.79e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  32 ELIGIMGPSGAGKSTFMNILAG-YRESgmKGQILVNG------RPRELRtfRKMScYIMQDDMLLpHLTVLEammvsaNL 104
Cdd:TIGR03375 492 EKVAIIGRIGSGKSTLLKLLLGlYQPT--EGSVLLDGvdirqiDPADLR--RNIG-YVPQDPRLF-YGTLRD------NI 559
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 105 KLSeKQEVKKELVTEILTALGLMSC--SHT---------RTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCF 173
Cdd:TIGR03375 560 ALG-APYADDEEILRAAELAGVTEFvrRHPdgldmqigeRGRSLSGGQRQAVALARALLRDPPILLLDEPTSAMDNRSEE 638
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 2462526932 174 QVVSLMKSLAqGGRTIICTIHQPSakLFEMFDKLYILSQGQCIFKG 219
Cdd:TIGR03375 639 RFKDRLKRWL-AGKTLVLVTHRTS--LLDLVDRIIVMDNGRIVADG 681
PRK13537 PRK13537
nodulation factor ABC transporter ATP-binding protein NodI;
16-225 4.80e-19

nodulation factor ABC transporter ATP-binding protein NodI;


Pssm-ID: 237420 [Multi-domain]  Cd Length: 306  Bit Score: 87.94  E-value: 4.80e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  16 GYKTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAGYRESgMKGQILVNGR--PRELRTFRKMSCYIMQDDMLLPHLT 93
Cdd:PRK13537   18 GDKLVVDGLSFHVQRGECFGLLGPNGAGKTTTLRMLLGLTHP-DAGSISLCGEpvPSRARHARQRVGVVPQFDNLDPDFT 96
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  94 VLEAMMVSAN-LKLSEKQevKKELVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASC 172
Cdd:PRK13537   97 VRENLLVFGRyFGLSAAA--ARALVPPLLEFAKLENKADAKVGELSGGMKRRLTLARALVNDPDVLVLDEPTTGLDPQAR 174
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2462526932 173 FQVVSLMKSLAQGGRTIICTIH--QPSAKLfemFDKLYILSQGQCIFKGVVTNLI 225
Cdd:PRK13537  175 HLMWERLRSLLARGKTILLTTHfmEEAERL---CDRLCVIEEGRKIAEGAPHALI 226
BtuD COG4138
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism]; ...
21-219 7.96e-19

ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism];


Pssm-ID: 443313 [Multi-domain]  Cd Length: 248  Bit Score: 86.05  E-value: 7.96e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  21 LKCLSGKFCRRELIGIMGPSGAGKSTFMNILAGYRESgmKGQILVNGRP------RELRTFRkmsCYIMQDDMLLPHLTV 94
Cdd:COG4138    12 LGPISAQVNAGELIHLIGPNGAGKSTLLARMAGLLPG--QGEILLNGRPlsdwsaAELARHR---AYLSQQQSPPFAMPV 86
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  95 LEAMMVSANLKLSEkqEVKKELVTEILTALGLMSCSHTRTALLSGG--QRKRLAIALELV---NNPP--VMFFDEPTSGL 167
Cdd:COG4138    87 FQYLALHQPAGASS--EAVEQLLAQLAEALGLEDKLSRPLTQLSGGewQRVRLAAVLLQVwptINPEgqLLLLDEPMNSL 164
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2462526932 168 DSAScfQVV--SLMKSLAQGGRTIICTIHQPSAKLFEMfDKLYILSQGQCIFKG 219
Cdd:COG4138   165 DVAQ--QAAldRLLRELCQQGITVVMSSHDLNHTLRHA-DRVWLLKQGKLVASG 215
PRK15134 PRK15134
microcin C ABC transporter ATP-binding protein YejF; Provisional
10-184 1.05e-18

microcin C ABC transporter ATP-binding protein YejF; Provisional


Pssm-ID: 237917 [Multi-domain]  Cd Length: 529  Bit Score: 89.38  E-value: 1.05e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  10 KRIVasGYKTLLKCLSGKFCRRELIGIMGPSGAGKSTfmNILAGYRESGMKGQILVNGRPRELRTFRKMSCY------IM 83
Cdd:PRK15134  293 KRTV--DHNVVVKNISFTLRPGETLGLVGESGSGKST--TGLALLRLINSQGEIWFDGQPLHNLNRRQLLPVrhriqvVF 368
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  84 QD--DMLLPHLTVLEamMVSANLKLSEKQ---EVKKELVTEILTALGLMSCSHTR-TALLSGGQRKRLAIALELVNNPPV 157
Cdd:PRK15134  369 QDpnSSLNPRLNVLQ--IIEEGLRVHQPTlsaAQREQQVIAVMEEVGLDPETRHRyPAEFSGGQRQRIAIARALILKPSL 446
                         170       180
                  ....*....|....*....|....*..
gi 2462526932 158 MFFDEPTSGLDSASCFQVVSLMKSLAQ 184
Cdd:PRK15134  447 IILDEPTSSLDKTVQAQILALLKSLQQ 473
ABC_OpuCA_Osmoprotection cd03295
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding ...
16-214 1.16e-18

ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213262 [Multi-domain]  Cd Length: 242  Bit Score: 85.43  E-value: 1.16e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  16 GYKTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAGYRESgMKGQILVNGR------PRELRtfRKMScYIMQDDMLL 89
Cdd:cd03295    12 GGKKAVNNLNLEIAKGEFLVLIGPSGSGKTTTMKMINRLIEP-TSGEIFIDGEdireqdPVELR--RKIG-YVIQQIGLF 87
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  90 PHLTVLEAmmVSANLKLSE-KQEVKKELVTEILTALGLMSCSHTR--TALLSGGQRKRLAIALELVNNPPVMFFDEPTSG 166
Cdd:cd03295    88 PHMTVEEN--IALVPKLLKwPKEKIRERADELLALVGLDPAEFADryPHELSGGQQQRVGVARALAADPPLLLMDEPFGA 165
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2462526932 167 LDSASCFQVVSLMKSLAQG-GRTIICTIHQpsakLFEMF---DKLYILSQGQ 214
Cdd:cd03295   166 LDPITRDQLQEEFKRLQQElGKTIVFVTHD----IDEAFrlaDRIAIMKNGE 213
PRK10584 PRK10584
putative ABC transporter ATP-binding protein YbbA; Provisional
30-196 1.85e-18

putative ABC transporter ATP-binding protein YbbA; Provisional


Pssm-ID: 182569 [Multi-domain]  Cd Length: 228  Bit Score: 84.45  E-value: 1.85e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  30 RRELIGIMGPSGAGKSTFMNILAGYrESGMKGQILVNGRP---------RELRTfrKMSCYIMQDDMLLPHLTVLEAMMV 100
Cdd:PRK10584   35 RGETIALIGESGSGKSTLLAILAGL-DDGSSGEVSLVGQPlhqmdeearAKLRA--KHVGFVFQSFMLIPTLNALENVEL 111
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 101 SANLKlSEKQEVKKELVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMK 180
Cdd:PRK10584  112 PALLR-GESSRQSRNGAKALLEQLGLGKRLDHLPAQLSGGEQQRVALARAFNGRPDVLFADEPTGNLDRQTGDKIADLLF 190
                         170
                  ....*....|....*..
gi 2462526932 181 SLAQG-GRTIICTIHQP 196
Cdd:PRK10584  191 SLNREhGTTLILVTHDL 207
MglA COG1129
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
35-190 3.10e-18

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440745 [Multi-domain]  Cd Length: 497  Bit Score: 87.77  E-value: 3.10e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  35 GIMGPSGAGKSTFMNILAG-YRESGmkGQILVNGRPRELRTFRK-------MscyIMQDDMLLPHLTVLEammvsaNLKL 106
Cdd:COG1129    34 ALLGENGAGKSTLMKILSGvYQPDS--GEILLDGEPVRFRSPRDaqaagiaI---IHQELNLVPNLSVAE------NIFL 102
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 107 SekQEVKK----------ELVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVV 176
Cdd:COG1129   103 G--REPRRgglidwramrRRARELLARLGLDIDPDTPVGDLSVAQQQLVEIARALSRDARVLILDEPTASLTEREVERLF 180
                         170
                  ....*....|....
gi 2462526932 177 SLMKSLAQGGRTII 190
Cdd:COG1129   181 RIIRRLKAQGVAII 194
ECF_ATPase_2 TIGR04521
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ...
21-219 3.51e-18

energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the downstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 275314 [Multi-domain]  Cd Length: 277  Bit Score: 84.81  E-value: 3.51e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  21 LKCLSGKFCRRELIGIMGPSGAGKSTFMNILAG-YRESgmKGQILVNGR------PRELRTFRKMSCYIMQddmlLPH-- 91
Cdd:TIGR04521  21 LDDVSLTIEDGEFVAIIGHTGSGKSTLIQHLNGlLKPT--SGTVTIDGRditakkKKKLKDLRKKVGLVFQ----FPEhq 94
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  92 ---LTVLEAMM-VSANLKLSEKqEVKkELVTEILTALGL------MSCSHtrtalLSGGQRKRLAIALELVNNPPVMFFD 161
Cdd:TIGR04521  95 lfeETVYKDIAfGPKNLGLSEE-EAE-ERVKEALELVGLdeeyleRSPFE-----LSGGQMRRVAIAGVLAMEPEVLILD 167
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2462526932 162 EPTSGLDSASCFQVVSLMKSLAQ-GGRTIICTIHQPSaKLFEMFDKLYILSQGQCIFKG 219
Cdd:TIGR04521 168 EPTAGLDPKGRKEILDLFKRLHKeKGLTVILVTHSME-DVAEYADRVIVMHKGKIVLDG 225
ABC_Pro_Gly_Betaine cd03294
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This ...
29-168 3.99e-18

ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This family comprises the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporters is the obligatory coupling of ATP hydrolysis to substrate translocation. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213261 [Multi-domain]  Cd Length: 269  Bit Score: 84.62  E-value: 3.99e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  29 CRRELIGIMGPSGAGKSTFMNILAGYRESgMKGQILVNGRP------RELRTFR--KMScYIMQDDMLLPHLTVLEAmmV 100
Cdd:cd03294    48 REGEIFVIMGLSGSGKSTLLRCINRLIEP-TSGKVLIDGQDiaamsrKELRELRrkKIS-MVFQSFALLPHRTVLEN--V 123
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2462526932 101 SANLKLS-EKQEVKKELVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLD 168
Cdd:cd03294   124 AFGLEVQgVPRAEREERAAEALELVGLEGWEHKYPDELSGGMQQRVGLARALAVDPDILLMDEAFSALD 192
cbiO PRK13652
cobalt transporter ATP-binding subunit; Provisional
6-221 4.25e-18

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 172200 [Multi-domain]  Cd Length: 277  Bit Score: 84.85  E-value: 4.25e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932   6 HAFQKRIVASGYKTLLKCLSG-KFC--RRELIGIMGPSGAGKSTFMNILAGYRESgMKGQILVNGRP---RELRTFRKMS 79
Cdd:PRK13652    2 HLIETRDLCYSYSGSKEALNNiNFIapRNSRIAVIGPNGAGKSTLFRHFNGILKP-TSGSVLIRGEPitkENIREVRKFV 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  80 CYIMQ--DDMLLPHLTVLEAMMVSANLKLSEkqEVKKELVTEILTALGLmscSHTRTAL---LSGGQRKRLAIALELVNN 154
Cdd:PRK13652   81 GLVFQnpDDQIFSPTVEQDIAFGPINLGLDE--ETVAHRVSSALHMLGL---EELRDRVphhLSGGEKKRVAIAGVIAME 155
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2462526932 155 PPVMFFDEPTSGLDSASCFQVVSLMKSLAQG-GRTIICTIHQPSAkLFEMFDKLYILSQGQCIFKGVV 221
Cdd:PRK13652  156 PQVLVLDEPTAGLDPQGVKELIDFLNDLPETyGMTVIFSTHQLDL-VPEMADYIYVMDKGRIVAYGTV 222
PRK11000 PRK11000
maltose/maltodextrin ABC transporter ATP-binding protein MalK;
32-213 4.31e-18

maltose/maltodextrin ABC transporter ATP-binding protein MalK;


Pssm-ID: 182893 [Multi-domain]  Cd Length: 369  Bit Score: 86.24  E-value: 4.31e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  32 ELIGIMGPSGAGKSTFMNILAGYRE--SG--MKGQILVNGRPRELRTFrKMscyIMQDDMLLPHLTVLEAMmvSANLKLS 107
Cdd:PRK11000   30 EFVVFVGPSGCGKSTLLRMIAGLEDitSGdlFIGEKRMNDVPPAERGV-GM---VFQSYALYPHLSVAENM--SFGLKLA 103
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 108 --EKQEVKK--ELVTEILTALGLMScshTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQ----VVSLM 179
Cdd:PRK11000  104 gaKKEEINQrvNQVAEVLQLAHLLD---RKPKALSGGQRQRVAIGRTLVAEPSVFLLDEPLSNLDAALRVQmrieISRLH 180
                         170       180       190
                  ....*....|....*....|....*....|....*
gi 2462526932 180 KSLaqgGRTIICTIH-QPSAklFEMFDKLYILSQG 213
Cdd:PRK11000  181 KRL---GRTMIYVTHdQVEA--MTLADKIVVLDAG 210
MdlB COG1132
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];
32-214 4.41e-18

ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];


Pssm-ID: 440747 [Multi-domain]  Cd Length: 579  Bit Score: 87.53  E-value: 4.41e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  32 ELIGIMGPSGAGKSTFMNILAGYRESGmKGQILVNGRP-RE--LRTFRKMSCYIMQDDMLLpHLTVLEammvsaNLKLSE 108
Cdd:COG1132   367 ETVALVGPSGSGKSTLVNLLLRFYDPT-SGRILIDGVDiRDltLESLRRQIGVVPQDTFLF-SGTIRE------NIRYGR 438
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 109 K----QEV----KKELVTEILTAL--GLmscsHT----RTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQ 174
Cdd:COG1132   439 PdatdEEVeeaaKAAQAHEFIEALpdGY----DTvvgeRGVNLSGGQRQRIAIARALLKDPPILILDEATSALDTETEAL 514
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 2462526932 175 VVSLMKSLAQgGRTIIcTI-HQPSAklFEMFDKLYILSQGQ 214
Cdd:COG1132   515 IQEALERLMK-GRTTI-VIaHRLST--IRNADRILVLDDGR 551
potA TIGR01187
spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine ...
36-214 5.19e-18

spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine/putrescine ABC transporter, ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. Polyamines like spermidine and putrescine play vital role in cell proliferation, differentiation, and ion homeostasis. The concentration of polyamines within the cell are regulated by biosynthesis, degradation and transport (uptake and efflux included). [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 162242 [Multi-domain]  Cd Length: 325  Bit Score: 85.24  E-value: 5.19e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  36 IMGPSGAGKSTFMNILAGYrESGMKGQILVNG-----RPRELRTFRKMscyiMQDDMLLPHLTVLEAmmVSANLKL-SEK 109
Cdd:TIGR01187   1 LLGPSGCGKTTLLRLLAGF-EQPDSGSIMLDGedvtnVPPHLRHINMV----FQSYALFPHMTVEEN--VAFGLKMrKVP 73
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 110 QEVKKELVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKSLA-QGGRT 188
Cdd:TIGR01187  74 RAEIKPRVLEALRLVQLEEFADRKPHQLSGGQQQRVALARALVFKPKILLLDEPLSALDKKLRDQMQLELKTIQeQLGIT 153
                         170       180
                  ....*....|....*....|....*.
gi 2462526932 189 IICTIHQPSAKLfEMFDKLYILSQGQ 214
Cdd:TIGR01187 154 FVFVTHDQEEAM-TMSDRIAIMRKGK 178
DppD COG0444
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ...
30-184 5.52e-18

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440213 [Multi-domain]  Cd Length: 320  Bit Score: 85.10  E-value: 5.52e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  30 RRELIGIMGPSGAGKSTFMNILAG-YRESGM-KGQILVNGR------PRELRTFR--KMScYIMQDDM--LLPHLTVLEA 97
Cdd:COG0444    30 RGETLGLVGESGSGKSTLARAILGlLPPPGItSGEILFDGEdllklsEKELRKIRgrEIQ-MIFQDPMtsLNPVMTVGDQ 108
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  98 MM--VSANLKLSEKQevKKELVTEILTALGLmscSHTRTAL------LSGGQRKRLAIALELVNNPPVMFFDEPTSGLD- 168
Cdd:COG0444   109 IAepLRIHGGLSKAE--ARERAIELLERVGL---PDPERRLdrypheLSGGMRQRVMIARALALEPKLLIADEPTTALDv 183
                         170
                  ....*....|....*...
gi 2462526932 169 --SAscfQVVSLMKSLAQ 184
Cdd:COG0444   184 tiQA---QILNLLKDLQR 198
ABC_NatA_sodium_exporter cd03266
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a ...
32-219 8.27e-18

ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.


Pssm-ID: 213233 [Multi-domain]  Cd Length: 218  Bit Score: 82.42  E-value: 8.27e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  32 ELIGIMGPSGAGKSTFMNILAGYRESGmKGQILVNG-----RPRELRtfRKMScyIMQDDM-LLPHLTVLEAMMVSANLK 105
Cdd:cd03266    32 EVTGLLGPNGAGKTTTLRMLAGLLEPD-AGFATVDGfdvvkEPAEAR--RRLG--FVSDSTgLYDRLTARENLEYFAGLY 106
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 106 LSEKQEVKKElVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKSLAQG 185
Cdd:cd03266   107 GLKGDELTAR-LEELADRLGMEELLDRRVGGFSTGMRQKVAIARALVHDPPVLLLDEPTTGLDVMATRALREFIRQLRAL 185
                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 2462526932 186 GRTIICTIH--QPSAKLfemFDKLYILSQGQCIFKG 219
Cdd:cd03266   186 GKCILFSTHimQEVERL---CDRVVVLHRGRVVYEG 218
ABC_CysA_sulfate_importer cd03296
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex ...
32-169 8.47e-18

ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-binding protein (cysP). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213263 [Multi-domain]  Cd Length: 239  Bit Score: 82.77  E-value: 8.47e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  32 ELIGIMGPSGAGKSTFMNILAGYrESGMKGQILVNGRPRELRTFRKMSC-YIMQDDMLLPHLTVLEAmmVSANLKLSEKQ 110
Cdd:cd03296    29 ELVALLGPSGSGKTTLLRLIAGL-ERPDSGTILFGGEDATDVPVQERNVgFVFQHYALFRHMTVFDN--VAFGLRVKPRS 105
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2462526932 111 EV-----KKELVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDS 169
Cdd:cd03296   106 ERppeaeIRAKVHELLKLVQLDWLADRYPAQLSGGQRQRVALARALAVEPKVLLLDEPFGALDA 169
CydC TIGR02868
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family ...
32-196 1.11e-17

thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex.


Pssm-ID: 274331 [Multi-domain]  Cd Length: 530  Bit Score: 86.26  E-value: 1.11e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  32 ELIGIMGPSGAGKSTFMNILAGYRESgMKGQILVNGRP---RELRTFRKMSCYIMQDdmllPHL---TVLEammvsaNLK 105
Cdd:TIGR02868 362 ERVAILGPSGSGKSTLLATLAGLLDP-LQGEVTLDGVPvssLDQDEVRRRVSVCAQD----AHLfdtTVRE------NLR 430
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 106 LSeKQEVKKELVTEILTALGL----------MSCS-HTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQ 174
Cdd:TIGR02868 431 LA-RPDATDEELWAALERVGLadwlralpdgLDTVlGEGGARLSGGERQRLALARALLADAPILLLDEPTEHLDAETADE 509
                         170       180
                  ....*....|....*....|..
gi 2462526932 175 VVSLMKSlAQGGRTIICTIHQP 196
Cdd:TIGR02868 510 LLEDLLA-ALSGRTVVLITHHL 530
PRK10895 PRK10895
lipopolysaccharide ABC transporter ATP-binding protein; Provisional
32-219 1.30e-17

lipopolysaccharide ABC transporter ATP-binding protein; Provisional


Pssm-ID: 182817 [Multi-domain]  Cd Length: 241  Bit Score: 82.63  E-value: 1.30e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  32 ELIGIMGPSGAGKSTFMNILAGY--RESGmkgQILVNGR-----PRELRTFRKMScYIMQDDMLLPHLTVLEAMMVSANL 104
Cdd:PRK10895   30 EIVGLLGPNGAGKTTTFYMVVGIvpRDAG---NIIIDDEdisllPLHARARRGIG-YLPQEASIFRRLSVYDNLMAVLQI 105
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 105 KLSEKQEVKKELVTEILTALGLmscSHTRTAL---LSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKS 181
Cdd:PRK10895  106 RDDLSAEQREDRANELMEEFHI---EHLRDSMgqsLSGGERRRVEIARALAANPKFILLDEPFAGVDPISVIDIKRIIEH 182
                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 2462526932 182 LAQGGRTIICTIHQPSAKLfEMFDKLYILSQGQCIFKG 219
Cdd:PRK10895  183 LRDSGLGVLITDHNVRETL-AVCERAYIVSQGHLIAHG 219
ABCC_MsbA cd03251
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; ...
32-219 1.83e-17

ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213218 [Multi-domain]  Cd Length: 234  Bit Score: 81.89  E-value: 1.83e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  32 ELIGIMGPSGAGKSTFMNILAGYRESGmKGQILVNG---RPRELRTFRKMSCYIMQDDMLLpHLTVLEAMM--------- 99
Cdd:cd03251    29 ETVALVGPSGSGKSTLVNLIPRFYDVD-SGRILIDGhdvRDYTLASLRRQIGLVSQDVFLF-NDTVAENIAygrpgatre 106
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 100 -VSANLKLSEKQEVKKELVTEILTALGlmscshTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSL 178
Cdd:cd03251   107 eVEEAARAANAHEFIMELPEGYDTVIG------ERGVKLSGGQRQRIAIARALLKDPPILILDEATSALDTESERLVQAA 180
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 2462526932 179 MKSLAQgGRTIICTIHQPSAklFEMFDKLYILSQGQCIFKG 219
Cdd:cd03251   181 LERLMK-NRTTFVIAHRLST--IENADRIVVLEDGKIVERG 218
Uup COG0488
ATPase components of ABC transporters with duplicated ATPase domains [General function ...
16-168 2.05e-17

ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];


Pssm-ID: 440254 [Multi-domain]  Cd Length: 520  Bit Score: 85.50  E-value: 2.05e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  16 GYKTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAGyRESGMKGQILvngRPRELRtfrkMScYIMQDDMLLPHLTVL 95
Cdd:COG0488     9 GGRPLLDDVSLSINPGDRIGLVGRNGAGKSTLLKILAG-ELEPDSGEVS---IPKGLR----IG-YLPQEPPLDDDLTVL 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  96 EAMMVS-------------ANLKLSEKQEVKKEL------------------VTEILTALGLMSCSHTR-TALLSGGQRK 143
Cdd:COG0488    80 DTVLDGdaelraleaeleeLEAKLAEPDEDLERLaelqeefealggweaearAEEILSGLGFPEEDLDRpVSELSGGWRR 159
                         170       180
                  ....*....|....*....|....*
gi 2462526932 144 RLAIALELVNNPPVMFFDEPTSGLD 168
Cdd:COG0488   160 RVALARALLSEPDLLLLDEPTNHLD 184
rim_protein TIGR01257
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...
28-219 2.08e-17

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]


Pssm-ID: 130324 [Multi-domain]  Cd Length: 2272  Bit Score: 86.61  E-value: 2.08e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932   28 FCRRELIGIMGPSGAGKSTFMNILAGYRESgMKGQILVNGRPRE--LRTFRKMSCYIMQDDMLLPHLTVLEAMMVSANLK 105
Cdd:TIGR01257  953 FYENQITAFLGHNGAGKTTTLSILTGLLPP-TSGTVLVGGKDIEtnLDAVRQSLGMCPQHNILFHHLTVAEHILFYAQLK 1031
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  106 LSEKQEVKKELvTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKSLAQG 185
Cdd:TIGR01257 1032 GRSWEEAQLEM-EAMLEDTGLHHKRNEEAQDLSGGMQRKLSVAIAFVGDAKVVVLDEPTSGVDPYSRRSIWDLLLKYRSG 1110
                          170       180       190
                   ....*....|....*....|....*....|....
gi 2462526932  186 GRTIICTIHQPSAKLfeMFDKLYILSQGQCIFKG 219
Cdd:TIGR01257 1111 RTIIMSTHHMDEADL--LGDRIAIISQGRLYCSG 1142
fecE PRK11231
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;
9-219 2.71e-17

Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;


Pssm-ID: 183044 [Multi-domain]  Cd Length: 255  Bit Score: 81.98  E-value: 2.71e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932   9 QKRIVASGYKTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAGYRESgMKGQILVNGRPRELRTFRKMSCYIMqddmL 88
Cdd:PRK11231    6 ENLTVGYGTKRILNDLSLSLPTGKITALIGPNGCGKSTLLKCFARLLTP-QSGTVFLGDKPISMLSSRQLARRLA----L 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  89 LP-HLTVLEAMMV--------SANL----KLSEKQEvkkELVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNP 155
Cdd:PRK11231   81 LPqHHLTPEGITVrelvaygrSPWLslwgRLSAEDN---ARVNQAMEQTRINHLADRRLTDLSGGQRQRAFLAMVLAQDT 157
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2462526932 156 PVMFFDEPTSGLDSASCFQVVSLMKSLAQGGRTIICTIH---QPSaklfEMFDKLYILSQGQCIFKG 219
Cdd:PRK11231  158 PVVLLDEPTTYLDINHQVELMRLMRELNTQGKTVVTVLHdlnQAS----RYCDHLVVLANGHVMAQG 220
cbiO PRK13644
energy-coupling factor transporter ATPase;
32-279 3.15e-17

energy-coupling factor transporter ATPase;


Pssm-ID: 106587 [Multi-domain]  Cd Length: 274  Bit Score: 81.96  E-value: 3.15e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  32 ELIGIMGPSGAGKSTFMNILAGYRESgMKGQILVNG----RPRELRTFRKMSCYIMQD-DMLLPHLTVLEAMMVSA-NLK 105
Cdd:PRK13644   29 EYIGIIGKNGSGKSTLALHLNGLLRP-QKGKVLVSGidtgDFSKLQGIRKLVGIVFQNpETQFVGRTVEEDLAFGPeNLC 107
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 106 LSeKQEVKKeLVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKSLAQG 185
Cdd:PRK13644  108 LP-PIEIRK-RVDRALAEIGLEKYRHRSPKTLSGGQGQCVALAGILTMEPECLIFDEVTSMLDPDSGIAVLERIKKLHEK 185
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 186 GRTIICTIHqpSAKLFEMFDKLYILSQGQCIFKGVVTNLI--PYLKGLGLHCPTyhnpadfIIEVASgeygdlnpmlfRA 263
Cdd:PRK13644  186 GKTIVYITH--NLEELHDADRIIVMDRGKIVLEGEPENVLsdVSLQTLGLTPPS-------LIELAE-----------NL 245
                         250
                  ....*....|....*.
gi 2462526932 264 VQNGLCAMAEKKSSPE 279
Cdd:PRK13644  246 KMHGVVIPWENTSSPS 261
potA PRK09452
spermidine/putrescine ABC transporter ATP-binding protein PotA;
32-168 3.39e-17

spermidine/putrescine ABC transporter ATP-binding protein PotA;


Pssm-ID: 236523 [Multi-domain]  Cd Length: 375  Bit Score: 83.46  E-value: 3.39e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  32 ELIGIMGPSGAGKSTFMNILAGYrESGMKGQILVNGR-----PRELR---TfrkmscyIMQDDMLLPHLTVLEAmmVSAN 103
Cdd:PRK09452   41 EFLTLLGPSGCGKTTVLRLIAGF-ETPDSGRIMLDGQdithvPAENRhvnT-------VFQSYALFPHMTVFEN--VAFG 110
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2462526932 104 LKLSE--KQEVKkELVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLD 168
Cdd:PRK09452  111 LRMQKtpAAEIT-PRVMEALRMVQLEEFAQRKPHQLSGGQQQRVAIARAVVNKPKVLLLDESLSALD 176
PRK14247 PRK14247
phosphate ABC transporter ATP-binding protein; Provisional
13-223 3.67e-17

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172735 [Multi-domain]  Cd Length: 250  Bit Score: 81.50  E-value: 3.67e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  13 VASGYKTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAG----YRESGMKGQILVNGR---PRELRTFRKMSCYIMQD 85
Cdd:PRK14247   11 VSFGQVEVLDGVNLEIPDNTITALMGPSGSGKSTLLRVFNRlielYPEARVSGEVYLDGQdifKMDVIELRRRVQMVFQI 90
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  86 DMLLPHLTVLEAmmVSANLKLSEKQEVKKEL---VTEILTALGLMSCSHTR----TALLSGGQRKRLAIALELVNNPPVM 158
Cdd:PRK14247   91 PNPIPNLSIFEN--VALGLKLNRLVKSKKELqerVRWALEKAQLWDEVKDRldapAGKLSGGQQQRLCIARALAFQPEVL 168
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2462526932 159 FFDEPTSGLDSASCFQVVSLMKSLAQgGRTIICTIHQPsAKLFEMFDKLYILSQGQCIFKG----VVTN 223
Cdd:PRK14247  169 LADEPTANLDPENTAKIESLFLELKK-DMTIVLVTHFP-QQAARISDYVAFLYKGQIVEWGptreVFTN 235
type_I_sec_HlyB TIGR01846
type I secretion system ABC transporter, HlyB family; Type I protein secretion is a system in ...
32-219 5.41e-17

type I secretion system ABC transporter, HlyB family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 273831 [Multi-domain]  Cd Length: 694  Bit Score: 84.41  E-value: 5.41e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  32 ELIGIMGPSGAGKSTFMNILAGYReSGMKGQILVNGR------PRELRtfRKMSCyIMQDDMLL------------PHLT 93
Cdd:TIGR01846 484 EFIGIVGPSGSGKSTLTKLLQRLY-TPQHGQVLVDGVdlaiadPAWLR--RQMGV-VLQENVLFsrsirdnialcnPGAP 559
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  94 VLEammVSANLKLSEKQEVKKELVTEILTALGlmscshTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCF 173
Cdd:TIGR01846 560 FEH---VIHAAKLAGAHDFISELPQGYNTEVG------EKGANLSGGQRQRIAIARALVGNPRILIFDEATSALDYESEA 630
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 2462526932 174 QVVSLMKSLAQgGRTIICTIHQPSAklFEMFDKLYILSQGQCIFKG 219
Cdd:TIGR01846 631 LIMRNMREICR-GRTVIIIAHRLST--VRACDRIIVLEKGQIAESG 673
metN PRK11153
DL-methionine transporter ATP-binding subunit; Provisional
32-223 6.11e-17

DL-methionine transporter ATP-binding subunit; Provisional


Pssm-ID: 236863 [Multi-domain]  Cd Length: 343  Bit Score: 82.54  E-value: 6.11e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  32 ELIGIMGPSGAGKSTF---MNILagyrESGMKGQILVNGR------PRELRTFRKmscyimQDDMLLPHLTVLEAMMVSA 102
Cdd:PRK11153   32 EIFGVIGASGAGKSTLircINLL----ERPTSGRVLVDGQdltalsEKELRKARR------QIGMIFQHFNLLSSRTVFD 101
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 103 N----LKLS--EKQEVKKElVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVV 176
Cdd:PRK11153  102 NvalpLELAgtPKAEIKAR-VTELLELVGLSDKADRYPAQLSGGQKQRVAIARALASNPKVLLCDEATSALDPATTRSIL 180
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2462526932 177 SLMKSL-AQGGRTIICTIHqpsaklfEM------FDKLYILSQGQCIFKGVVTN 223
Cdd:PRK11153  181 ELLKDInRELGLTIVLITH-------EMdvvkriCDRVAVIDAGRLVEQGTVSE 227
TauB COG4525
ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];
30-169 6.44e-17

ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443596 [Multi-domain]  Cd Length: 262  Bit Score: 80.68  E-value: 6.44e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  30 RRELIGIMGPSGAGKSTFMNILAGYrESGMKGQILVNGRP-------RELrtfrkmscyIMQDDMLLPHLTVLEAmmVSA 102
Cdd:COG4525    32 SGEFVVALGASGCGKTTLLNLIAGF-LAPSSGEITLDGVPvtgpgadRGV---------VFQKDALLPWLNVLDN--VAF 99
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2462526932 103 NLKLS--EKQEvKKELVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDS 169
Cdd:COG4525   100 GLRLRgvPKAE-RRARAEELLALVGLADFARRRIWQLSGGMRQRVGIARALAADPRFLLMDEPFGALDA 167
modC_ABC TIGR02142
molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding ...
32-214 6.46e-17

molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding cassette (ABC) protein of the three subunit molybdate ABC transporter. The three proteins of this complex are homologous to proteins of the sulfate ABC transporter. Molybdenum may be used in nitrogenases of nitrogen-fixing bacteria and in molybdopterin cofactors. In some cases, molybdate may be transported by a sulfate transporter rather than by a specific molybdate transporter. [Transport and binding proteins, Anions]


Pssm-ID: 131197 [Multi-domain]  Cd Length: 354  Bit Score: 82.47  E-value: 6.46e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  32 ELIGIMGPSGAGKSTFMNILAGYrESGMKGQILVNGR-----------PRELRTFRkmscYIMQDDMLLPHLTVLEAMMV 100
Cdd:TIGR02142  24 GVTAIFGRSGSGKTTLIRLIAGL-TRPDEGEIVLNGRtlfdsrkgiflPPEKRRIG----YVFQEARLFPHLSVRGNLRY 98
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 101 SANLKLSEKQEVKKELVTEILtalGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMK 180
Cdd:TIGR02142  99 GMKRARPSERRISFERVIELL---GIGHLLGRLPGRLSGGEKQRVAIGRALLSSPRLLLMDEPLAALDDPRKYEILPYLE 175
                         170       180       190
                  ....*....|....*....|....*....|....
gi 2462526932 181 SLAQGGRTIICTIHQPSAKLFEMFDKLYILSQGQ 214
Cdd:TIGR02142 176 RLHAEFGIPILYVSHSLQEVLRLADRVVVLEDGR 209
ABCC_Hemolysin cd03252
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a ...
32-219 7.60e-17

ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a central component of the secretion machinery that translocates the toxin, hemolysin A, in a Sec-independent fashion across both membranes of E. coli. The hemolysin A (HlyA) transport machinery is composed of the ATP-binding cassette (ABC) transporter HlyB located in the inner membrane, hemolysin D (HlyD), also anchored in the inner membrane, and TolC, which resides in the outer membrane. HlyD apparently forms a continuous channel that bridges the entire periplasm, interacting with TolC and HlyB. This arrangement prevents the appearance of periplasmic intermediates of HlyA during substrate transport. Little is known about the molecular details of HlyA transport, but it is evident that ATP-hydrolysis by the ABC-transporter HlyB is a necessary source of energy.


Pssm-ID: 213219 [Multi-domain]  Cd Length: 237  Bit Score: 80.22  E-value: 7.60e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  32 ELIGIMGPSGAGKSTFMNILAGYRESGmKGQILVNGRPR---ELRTFRKMSCYIMQDDMLLpHLTVLE-------AM--- 98
Cdd:cd03252    29 EVVGIVGRSGSGKSTLTKLIQRFYVPE-NGRVLVDGHDLalaDPAWLRRQVGVVLQENVLF-NRSIRDnialadpGMsme 106
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  99 MVSANLKLSEKQEVKKELVTEILTALGlmscshTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSL 178
Cdd:cd03252   107 RVIEAAKLAGAHDFISELPEGYDTIVG------EQGAGLSGGQRQRIAIARALIHNPRILIFDEATSALDYESEHAIMRN 180
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 2462526932 179 MKSLAQgGRTIICTIHQPSAklFEMFDKLYILSQGQCIFKG 219
Cdd:cd03252   181 MHDICA-GRTVIIIAHRLST--VKNADRIIVMEKGRIVEQG 218
AztA NF040873
zinc ABC transporter ATP-binding protein AztA;
19-196 8.51e-17

zinc ABC transporter ATP-binding protein AztA;


Pssm-ID: 468810 [Multi-domain]  Cd Length: 191  Bit Score: 78.81  E-value: 8.51e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  19 TLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAGYResgmkgqilvngRPRELRTFRKMSC---YIMQ---DDMLLPhL 92
Cdd:NF040873    6 PVLHGVDLTIPAGSLTAVVGPNGSGKSTLLKVLAGVL------------RPTSGTVRRAGGArvaYVPQrseVPDSLP-L 72
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  93 TVLEAMMVSANLKLSEKQEVKKE---LVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDS 169
Cdd:NF040873   73 TVRDLVAMGRWARRGLWRRLTRDdraAVDDALERVGLADLAGRQLGELSGGQRQRALLAQGLAQEADLLLLDEPTTGLDA 152
                         170       180
                  ....*....|....*....|....*..
gi 2462526932 170 ASCFQVVSLMKSLAQGGRTIICTIHQP 196
Cdd:NF040873  153 ESRERIIALLAEEHARGATVVVVTHDL 179
PRK14246 PRK14246
phosphate ABC transporter ATP-binding protein; Provisional
18-196 1.03e-16

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172734 [Multi-domain]  Cd Length: 257  Bit Score: 80.09  E-value: 1.03e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  18 KTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAGYRE---SGMK--GQILVNGRPR---ELRTFRKMSCYIMQDDMLL 89
Cdd:PRK14246   23 KAILKDITIKIPNNSIFGIMGPSGSGKSTLLKVLNRLIEiydSKIKvdGKVLYFGKDIfqiDAIKLRKEVGMVFQQPNPF 102
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  90 PHLTVLEAmmVSANLK---LSEKQEVKKeLVTEILTALGLMSCSHTR----TALLSGGQRKRLAIALELVNNPPVMFFDE 162
Cdd:PRK14246  103 PHLSIYDN--IAYPLKshgIKEKREIKK-IVEECLRKVGLWKEVYDRlnspASQLSGGQQQRLTIARALALKPKVLLMDE 179
                         170       180       190
                  ....*....|....*....|....*....|....
gi 2462526932 163 PTSGLDSASCFQVVSLMKSLaQGGRTIICTIHQP 196
Cdd:PRK14246  180 PTSMIDIVNSQAIEKLITEL-KNEIAIVIVSHNP 212
ntrCD TIGR01184
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits ...
32-213 1.41e-16

nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits of nitrate transport in bacteria and archaea. This protein belongs to the ATP-binding cassette (ABC) superfamily. It is thought that the two subunits encoded by ntrC and ntrD form the binding surface for interaction with ATP. This model is restricted in identifying ATP binding subunit associated with the nitrate transport. Nitrate assimilation is aided by other proteins derived from the operon which among others include products of ntrA - a regulatory protein; ntrB - a hydropbobic transmembrane permease and narB - a reductase. [Transport and binding proteins, Anions, Transport and binding proteins, Other]


Pssm-ID: 130252 [Multi-domain]  Cd Length: 230  Bit Score: 79.05  E-value: 1.41e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  32 ELIGIMGPSGAGKSTFMNILAGYrESGMKGQILVNGRPRELRTFRKMscYIMQDDMLLPHLTVLE--AMMVSANLKLSEK 109
Cdd:TIGR01184  12 EFISLIGHSGCGKSTLLNLISGL-AQPTSGGVILEGKQITEPGPDRM--VVFQNYSLLPWLTVREniALAVDRVLPDLSK 88
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 110 QEvKKELVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVS-LMKSLAQGGRT 188
Cdd:TIGR01184  89 SE-RRAIVEEHIALVGLTEAADKRPGQLSGGMKQRVAIARALSIRPKVLLLDEPFGALDALTRGNLQEeLMQIWEEHRVT 167
                         170       180
                  ....*....|....*....|....*
gi 2462526932 189 IICTIHQPSAKLFeMFDKLYILSQG 213
Cdd:TIGR01184 168 VLMVTHDVDEALL-LSDRVVMLTNG 191
ABCC_cytochrome_bd cd03247
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome ...
18-219 1.41e-16

ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome bd biogenesis. The CydC and CydD proteins are important for the formation of cytochrome bd terminal oxidase of E. coli and it has been proposed that they were necessary for biosynthesis of the cytochrome bd quinol oxidase and for periplasmic c-type cytochromes. CydCD were proposed to determine a heterooligomeric complex important for heme export into the periplasm or to be involved in the maintenance of the proper redox state of the periplasmic space. In Bacillus subtilis, the absence of CydCD does not affect the presence of halo-cytochrome c in the membrane and this observation suggests that CydCD proteins are not involved in the export of heme in this organism.


Pssm-ID: 213214 [Multi-domain]  Cd Length: 178  Bit Score: 77.74  E-value: 1.41e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  18 KTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAGYRESgMKGQILVNGRPREL--RTFRKMSCYIMQDdmllPHLtvl 95
Cdd:cd03247    15 QQVLKNLSLELKQGEKIALLGRSGSGKSTLLQLLTGDLKP-QQGEITLDGVPVSDleKALSSLISVLNQR----PYL--- 86
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  96 eammvsanlklsekqevkkeLVTEILTALGLMscshtrtalLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQV 175
Cdd:cd03247    87 --------------------FDTTLRNNLGRR---------FSGGERQRLALARILLQDAPIVLLDEPTVGLDPITERQL 137
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 2462526932 176 VSLMKSLAQgGRTIICTIHQPSAklFEMFDKLYILSQGQCIFKG 219
Cdd:cd03247   138 LSLIFEVLK-DKTLIWITHHLTG--IEHMDKILFLENGKIIMQG 178
COG4559 COG4559
ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];
13-219 1.59e-16

ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443620 [Multi-domain]  Cd Length: 258  Bit Score: 79.77  E-value: 1.59e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  13 VASGYKTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAGYRESGmKGQILVNGRPRELRTFRKMSCY--IM-QDDMLL 89
Cdd:COG4559     9 VRLGGRTLLDDVSLTLRPGELTAIIGPNGAGKSTLLKLLTGELTPS-SGEVRLNGRPLAAWSPWELARRraVLpQHSSLA 87
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  90 PHLTVLE--AMMVSANlklSEKQEVKKELVTEILTALGLMSCSHTRTALLSGG--QRKRLAIAL----ELVNNPP-VMFF 160
Cdd:COG4559    88 FPFTVEEvvALGRAPH---GSSAAQDRQIVREALALVGLAHLAGRSYQTLSGGeqQRVQLARVLaqlwEPVDGGPrWLFL 164
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 161 DEPTSGLDSASCFQVVSLMKSLAQGGRTIICTIHQPSakLFEMF-DKLYILSQGQCIFKG 219
Cdd:COG4559   165 DEPTSALDLAHQHAVLRLARQLARRGGGVVAVLHDLN--LAAQYaDRILLLHQGRLVAQG 222
hmuV PRK13548
hemin importer ATP-binding subunit; Provisional
32-216 3.21e-16

hemin importer ATP-binding subunit; Provisional


Pssm-ID: 237422 [Multi-domain]  Cd Length: 258  Bit Score: 78.66  E-value: 3.21e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  32 ELIGIMGPSGAGKSTFMNILAGYRESGmKGQILVNGR------PRELRTFRKMscyimqddmlLPH-------LTVLE-- 96
Cdd:PRK13548   29 EVVAILGPNGAGKSTLLRALSGELSPD-SGEVRLNGRpladwsPAELARRRAV----------LPQhsslsfpFTVEEvv 97
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  97 AMMVSAnlkLSEKQEVKKELVTEILTALGlmsCSHTRTAL---LSGG--QRKRLAIAL----ELVNNPPVMFFDEPTSGL 167
Cdd:PRK13548   98 AMGRAP---HGLSRAEDDALVAAALAQVD---LAHLAGRDypqLSGGeqQRVQLARVLaqlwEPDGPPRWLLLDEPTSAL 171
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2462526932 168 DSASCFQVVSLMKSLA-QGGRTIICTIHqpSAKLFEMF-DKLYILSQGQCI 216
Cdd:PRK13548  172 DLAHQHHVLRLARQLAhERGLAVIVVLH--DLNLAARYaDRIVLLHQGRLV 220
ABCC_ATM1_transporter cd03253
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC ...
34-219 4.68e-16

ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC transporter that is expressed in the mitochondria. Although the specific function of ATM1 is unknown, its disruption results in the accumulation of excess mitochondrial iron, loss of mitochondrial cytochromes, oxidative damage to mitochondrial DNA, and decreased levels of cytosolic heme proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213220 [Multi-domain]  Cd Length: 236  Bit Score: 77.66  E-value: 4.68e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  34 IGIMGPSGAGKSTFMNILAGYRESgMKGQILVNGRP-RE--LRTFRKMSCYIMQDdMLLPHLTVLEAMMVsANLKLSEKQ 110
Cdd:cd03253    30 VAIVGPSGSGKSTILRLLFRFYDV-SSGSILIDGQDiREvtLDSLRRAIGVVPQD-TVLFNDTIGYNIRY-GRPDATDEE 106
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 111 EV---KKELVTEILTAL-----------GLMscshtrtalLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVV 176
Cdd:cd03253   107 VIeaaKAAQIHDKIMRFpdgydtivgerGLK---------LSGGEKQRVAIARAILKNPPILLLDEATSALDTHTEREIQ 177
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 2462526932 177 SLMKSLAQgGRTIICTIHQPS----AklfemfDKLYILSQGQCIFKG 219
Cdd:cd03253   178 AALRDVSK-GRTTIVIAHRLStivnA------DKIIVLKDGRIVERG 217
PRK14271 PRK14271
phosphate ABC transporter ATP-binding protein; Provisional
18-224 5.41e-16

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172759 [Multi-domain]  Cd Length: 276  Bit Score: 78.60  E-value: 5.41e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  18 KTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNIL-------AGYRESGmkgQILVNGRP----RELRTFRKMSCYIMQDD 86
Cdd:PRK14271   34 KTVLDQVSMGFPARAVTSLMGPTGSGKTTFLRTLnrmndkvSGYRYSG---DVLLGGRSifnyRDVLEFRRRVGMLFQRP 110
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  87 MLLPhLTVLEAMMVSANL-KLSEKQEVKKeLVTEILTALGLMSCSHTRTA----LLSGGQRKRLAIALELVNNPPVMFFD 161
Cdd:PRK14271  111 NPFP-MSIMDNVLAGVRAhKLVPRKEFRG-VAQARLTEVGLWDAVKDRLSdspfRLSGGQQQLLCLARTLAVNPEVLLLD 188
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2462526932 162 EPTSGLDSASCFQVVSLMKSLAQggRTIICTIHQPSAKLFEMFDKLYILSQGQCIFKGVVTNL 224
Cdd:PRK14271  189 EPTSALDPTTTEKIEEFIRSLAD--RLTVIIVTHNLAQAARISDRAALFFDGRLVEEGPTEQL 249
ModC COG4148
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and ...
31-171 6.62e-16

ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, ATPase component ModC is part of the Pathway/BioSystem: Molybdopterin biosynthesis


Pssm-ID: 443319 [Multi-domain]  Cd Length: 358  Bit Score: 79.37  E-value: 6.62e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  31 RELIGIMGPSGAGKSTFMNILAGYrESGMKGQILVNGRP---RELRTF-----RKMScYIMQDDMLLPHLTVLEammvsa 102
Cdd:COG4148    25 RGVTALFGPSGSGKTTLLRAIAGL-ERPDSGRIRLGGEVlqdSARGIFlpphrRRIG-YVFQEARLFPHLSVRG------ 96
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2462526932 103 NLKLSEKQEVK---KELVTEILTALGLmscSH---TRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSAS 171
Cdd:COG4148    97 NLLYGRKRAPRaerRISFDEVVELLGI---GHlldRRPATLSGGERQRVAIGRALLSSPRLLLMDEPLAALDLAR 168
PRK10575 PRK10575
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;
18-194 6.90e-16

Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;


Pssm-ID: 182561 [Multi-domain]  Cd Length: 265  Bit Score: 77.91  E-value: 6.90e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  18 KTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILaGYRESGMKGQILVNGRPREL---RTFRKMSCYIMQDdmlLPH--- 91
Cdd:PRK10575   24 RTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKML-GRHQPPSEGEILLDAQPLESwssKAFARKVAYLPQQ---LPAaeg 99
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  92 LTVLEAMMVSA---NLKLSEKQEVKKELVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLD 168
Cdd:PRK10575  100 MTVRELVAIGRypwHGALGRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDEPTSALD 179
                         170       180
                  ....*....|....*....|....*..
gi 2462526932 169 SASCFQVVSLMKSLAQG-GRTIICTIH 194
Cdd:PRK10575  180 IAHQVDVLALVHRLSQErGLTVIAVLH 206
ABC_Carb_Monos_I cd03216
First domain of the ATP-binding cassette component of monosaccharide transport system; This ...
30-216 9.08e-16

First domain of the ATP-binding cassette component of monosaccharide transport system; This family represents the domain I of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. Pentoses include xylose, arabinose, and ribose. Important hexoses include glucose, galactose, and fructose. In members of the Carb_monos family, the single hydrophobic gene product forms a homodimer while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.


Pssm-ID: 213183 [Multi-domain]  Cd Length: 163  Bit Score: 75.16  E-value: 9.08e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  30 RRELIGIMGPSGAGKSTFMNILAGYRESGmKGQILVNGRPRELRTFRkmscyimqddmllphltvlEAMmvsanlklsek 109
Cdd:cd03216    25 RGEVHALLGENGAGKSTLMKILSGLYKPD-SGEILVDGKEVSFASPR-------------------DAR----------- 73
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 110 qevkkelvteiltALGlMSCSHTrtalLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKSLAQGGRTI 189
Cdd:cd03216    74 -------------RAG-IAMVYQ----LSVGERQMVEIARALARNARLLILDEPTAALTPAEVERLFKVIRRLRAQGVAV 135
                         170       180       190
                  ....*....|....*....|....*....|
gi 2462526932 190 ICTIHqpsaKLFEMF---DKLYILSQGQCI 216
Cdd:cd03216   136 IFISH----RLDEVFeiaDRVTVLRDGRVV 161
ABC_MTABC3_MDL1_MDL2 cd03249
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 ...
21-219 1.56e-15

ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 (also known as ABCB6) is a mitochondrial ATP-binding cassette protein involved in iron homeostasis and one of four ABC transporters expressed in the mitochondrial inner membrane, the other three being MDL1(ABC7), MDL2, and ATM1. In fact, the yeast MDL1 (multidrug resistance-like protein 1) and MDL2 (multidrug resistance-like protein 2) transporters are also included in this CD. MDL1 is an ATP-dependent permease that acts as a high-copy suppressor of ATM1 and is thought to have a role in resistance to oxidative stress. Interestingly, subfamily B is more closely related to the carboxyl-terminal component of subfamily C than the two halves of ABCC molecules are with one another.


Pssm-ID: 213216 [Multi-domain]  Cd Length: 238  Bit Score: 76.42  E-value: 1.56e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  21 LKCLSGKFCRRELIGIMGPSGAGKSTFMNILAGYRESgMKGQILVNG---RPRELRTFRKMSCYIMQDdmllPHL---TV 94
Cdd:cd03249    19 LKGLSLTIPPGKTVALVGSSGCGKSTVVSLLERFYDP-TSGEILLDGvdiRDLNLRWLRSQIGLVSQE----PVLfdgTI 93
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  95 LEAMMVSAN-LKLSEKQEV-KKELVTEILTAL--GLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSA 170
Cdd:cd03249    94 AENIRYGKPdATDEEVEEAaKKANIHDFIMSLpdGYDTLVGERGSQLSGGQKQRIAIARALLRNPKILLLDEATSALDAE 173
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2462526932 171 SCFQVvslMKSL--AQGGRTIICTIHQPSAklFEMFDKLYILSQGQCIFKG 219
Cdd:cd03249   174 SEKLV---QEALdrAMKGRTTIVIAHRLST--IRNADLIAVLQNGQVVEQG 219
YhaQ COG4152
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
32-219 2.33e-15

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 443322 [Multi-domain]  Cd Length: 298  Bit Score: 77.07  E-value: 2.33e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  32 ELIGIMGPSGAGKSTFMNILAG--YRESGmkgQILVNGRPRELRTFRKMScYimqddM-----LLPHLTVLEAMMVSANL 104
Cdd:COG4152    28 EIFGLLGPNGAGKTTTIRIILGilAPDSG---EVLWDGEPLDPEDRRRIG-Y-----LpeergLYPKMKVGEQLVYLARL 98
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 105 KLSEKQEVKKELvTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSAScfqvVSLMKS--- 181
Cdd:COG4152    99 KGLSKAEAKRRA-DEWLERLGLGDRANKKVEELSKGNQQKVQLIAALLHDPELLILDEPFSGLDPVN----VELLKDvir 173
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 2462526932 182 -LAQGGRTIICTIHQ-PSAKlfEMFDKLYILSQGQCIFKG 219
Cdd:COG4152   174 eLAAKGTTVIFSSHQmELVE--ELCDRIVIINKGRKVLSG 211
potG PRK11607
putrescine ABC transporter ATP-binding subunit PotG;
32-168 2.35e-15

putrescine ABC transporter ATP-binding subunit PotG;


Pssm-ID: 183226 [Multi-domain]  Cd Length: 377  Bit Score: 77.95  E-value: 2.35e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  32 ELIGIMGPSGAGKSTFMNILAGYrESGMKGQILVNGR-----PRELRTFRKMscyiMQDDMLLPHLTVleammvSANLKL 106
Cdd:PRK11607   46 EIFALLGASGCGKSTLLRMLAGF-EQPTAGQIMLDGVdlshvPPYQRPINMM----FQSYALFPHMTV------EQNIAF 114
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2462526932 107 SEKQE--VKKEL---VTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLD 168
Cdd:PRK11607  115 GLKQDklPKAEIasrVNEMLGLVHMQEFAKRKPHQLSGGQRQRVALARSLAKRPKLLLLDEPMGALD 181
LivF COG0410
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid ...
32-167 2.47e-15

ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid transport and metabolism];


Pssm-ID: 440179 [Multi-domain]  Cd Length: 236  Bit Score: 75.79  E-value: 2.47e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  32 ELIGIMGPSGAGKSTFMNILAGYRESgMKGQILVNGRP-RELRTFRKMS---CYIMQDDMLLPHLTVLEammvsaNLKL- 106
Cdd:COG0410    30 EIVALLGRNGAGKTTLLKAISGLLPP-RSGSIRFDGEDiTGLPPHRIARlgiGYVPEGRRIFPSLTVEE------NLLLg 102
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2462526932 107 ----SEKQEVKK--ELVTEILTALGLMScsHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGL 167
Cdd:COG0410   103 ayarRDRAEVRAdlERVYELFPRLKERR--RQRAGTLSGGEQQMLAIGRALMSRPKLLLLDEPSLGL 167
NupO COG3845
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ...
35-190 2.93e-15

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];


Pssm-ID: 443055 [Multi-domain]  Cd Length: 504  Bit Score: 78.53  E-value: 2.93e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  35 GIMGPSGAGKSTFMNILAG-YR-ESgmkGQILVNGRPRELRTFRK-MSCYI-M--QDDMLLPHLTVLE----AMMVSANL 104
Cdd:COG3845    35 ALLGENGAGKSTLMKILYGlYQpDS---GEILIDGKPVRIRSPRDaIALGIgMvhQHFMLVPNLTVAEnivlGLEPTKGG 111
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 105 KLSEKQEVKKelVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGL---DSASCFQVvslMKS 181
Cdd:COG3845   112 RLDRKAARAR--IRELSERYGLDVDPDAKVEDLSVGEQQRVEILKALYRGARILILDEPTAVLtpqEADELFEI---LRR 186

                  ....*....
gi 2462526932 182 LAQGGRTII 190
Cdd:COG3845   187 LAAEGKSII 195
PRK11174 PRK11174
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
18-219 3.11e-15

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed


Pssm-ID: 236870 [Multi-domain]  Cd Length: 588  Bit Score: 78.73  E-value: 3.11e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  18 KTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAG---YResgmkGQILVNG---RPRELRTFRKMSCYIMQDDmLLPH 91
Cdd:PRK11174  363 KTLAGPLNFTLPAGQRIALVGPSGAGKTSLLNALLGflpYQ-----GSLKINGielRELDPESWRKHLSWVGQNP-QLPH 436
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  92 LTVLEAMMVsANLKLSE---KQEVKKELVTEILTAL--GLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSG 166
Cdd:PRK11174  437 GTLRDNVLL-GNPDASDeqlQQALENAWVSEFLPLLpqGLDTPIGDQAAGLSVGQAQRLALARALLQPCQLLLLDEPTAS 515
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2462526932 167 LDSASCFQVVSLMKSLAQGGRTIICTiHQPSAkLFEMfDKLYILSQGQCIFKG 219
Cdd:PRK11174  516 LDAHSEQLVMQALNAASRRQTTLMVT-HQLED-LAQW-DQIWVMQDGQIVQQG 565
ABC_NatA_like cd03267
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; ...
18-219 3.95e-15

ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.


Pssm-ID: 213234 [Multi-domain]  Cd Length: 236  Bit Score: 75.06  E-value: 3.95e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  18 KTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAG-YRESGmkGQILVNG-RP--RELRTFRKMSCYIMQDDMLLPHLT 93
Cdd:cd03267    34 VEALKGISFTIEKGEIVGFIGPNGAGKTTTLKILSGlLQPTS--GEVRVAGlVPwkRRKKFLRRIGVVFGQKTQLWWDLP 111
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  94 VLEAMMVSANLKLSEKQEVKKELvTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCF 173
Cdd:cd03267   112 VIDSFYLLAAIYDLPPARFKKRL-DELSELLDLEELLDTPVRQLSLGQRMRAEIAAALLHEPEILFLDEPTIGLDVVAQE 190
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 2462526932 174 QVVSLMKSL-AQGGRTIICTIH--QPSAKLfemFDKLYILSQGQCIFKG 219
Cdd:cd03267   191 NIRNFLKEYnRERGTTVLLTSHymKDIEAL---ARRVLVIDKGRLLYDG 236
tauB PRK11248
taurine ABC transporter ATP-binding subunit;
32-213 5.75e-15

taurine ABC transporter ATP-binding subunit;


Pssm-ID: 183056 [Multi-domain]  Cd Length: 255  Bit Score: 75.12  E-value: 5.75e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  32 ELIGIMGPSGAGKSTFMNILAGYRESGmKGQILVNGRPRELRTFRKmsCYIMQDDMLLPHLTVLEAMMVSANLKLSEKQE 111
Cdd:PRK11248   28 ELLVVLGPSGCGKTTLLNLIAGFVPYQ-HGSITLDGKPVEGPGAER--GVVFQNEGLLPWRNVQDNVAFGLQLAGVEKMQ 104
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 112 vKKELVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKSLAQG-GRTII 190
Cdd:PRK11248  105 -RLEIAHQMLKKVGLEGAEKRYIWQLSGGQRQRVGIARALAANPQLLLLDEPFGALDAFTREQMQTLLLKLWQEtGKQVL 183
                         170       180
                  ....*....|....*....|...
gi 2462526932 191 CTIHQPSAKLFeMFDKLYILSQG 213
Cdd:PRK11248  184 LITHDIEEAVF-MATELVLLSPG 205
PRK13538 PRK13538
cytochrome c biogenesis heme-transporting ATPase CcmA;
32-196 6.14e-15

cytochrome c biogenesis heme-transporting ATPase CcmA;


Pssm-ID: 184125 [Multi-domain]  Cd Length: 204  Bit Score: 73.68  E-value: 6.14e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  32 ELIGIMGPSGAGKSTFMNILAG--YRESGmkgQILVNGRP-RELRT-FRKMSCYIMQDDMLLPHLTVLEammvsaNLKLS 107
Cdd:PRK13538   28 ELVQIEGPNGAGKTSLLRILAGlaRPDAG---EVLWQGEPiRRQRDeYHQDLLYLGHQPGIKTELTALE------NLRFY 98
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 108 EK--QEVKKELVTEILTALGL-----MSCSHtrtalLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMK 180
Cdd:PRK13538   99 QRlhGPGDDEALWEALAQVGLagfedVPVRQ-----LSAGQQRRVALARLWLTRAPLWILDEPFTAIDKQGVARLEALLA 173
                         170
                  ....*....|....*.
gi 2462526932 181 SLAQGGRTIICTIHQP 196
Cdd:PRK13538  174 QHAEQGGMVILTTHQD 189
PRK10908 PRK10908
cell division ATP-binding protein FtsE;
32-194 8.54e-15

cell division ATP-binding protein FtsE;


Pssm-ID: 182829 [Multi-domain]  Cd Length: 222  Bit Score: 73.76  E-value: 8.54e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  32 ELIGIMGPSGAGKSTFMNILAGYrESGMKGQILVNG------RPRELRTFRKMSCYIMQDDMLLPHLTVLEAMMVSANLK 105
Cdd:PRK10908   29 EMAFLTGHSGAGKSTLLKLICGI-ERPSAGKIWFSGhditrlKNREVPFLRRQIGMIFQDHHLLMDRTVYDNVAIPLIIA 107
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 106 LSEKQEVKKElVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKSLAQG 185
Cdd:PRK10908  108 GASGDDIRRR-VSAALDKVGLLDKAKNFPIQLSGGEQQRVGIARAVVNKPAVLLADEPTGNLDDALSEGILRLFEEFNRV 186

                  ....*....
gi 2462526932 186 GRTIICTIH 194
Cdd:PRK10908  187 GVTVLMATH 195
araG PRK11288
L-arabinose ABC transporter ATP-binding protein AraG;
35-214 1.04e-14

L-arabinose ABC transporter ATP-binding protein AraG;


Pssm-ID: 183077 [Multi-domain]  Cd Length: 501  Bit Score: 76.87  E-value: 1.04e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  35 GIMGPSGAGKSTFMNILAG-YRESGmkGQILVNGRPRELRTFRKM----SCYIMQDDMLLPHLTVLEAMMVS---ANLKL 106
Cdd:PRK11288   34 ALMGENGAGKSTLLKILSGnYQPDA--GSILIDGQEMRFASTTAAlaagVAIIYQELHLVPEMTVAENLYLGqlpHKGGI 111
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 107 SEKQEVKKElVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKSLAQGG 186
Cdd:PRK11288  112 VNRRLLNYE-AREQLEHLGVDIDPDTPLKYLSIGQRQMVEIAKALARNARVIAFDEPTSSLSAREIEQLFRVIRELRAEG 190
                         170       180
                  ....*....|....*....|....*...
gi 2462526932 187 RTIICTIHQpSAKLFEMFDKLYILSQGQ 214
Cdd:PRK11288  191 RVILYVSHR-MEEIFALCDAITVFKDGR 217
PRK11160 PRK11160
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
21-219 1.05e-14

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed


Pssm-ID: 236865 [Multi-domain]  Cd Length: 574  Bit Score: 77.17  E-value: 1.05e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  21 LKCLSGKFCRRELIGIMGPSGAGKSTFMNILAGYRESGmKGQILVNGRP----RElRTFRKMSCYIMQDdmllPHL---T 93
Cdd:PRK11160  356 LKGLSLQIKAGEKVALLGRTGCGKSTLLQLLTRAWDPQ-QGEILLNGQPiadySE-AALRQAISVVSQR----VHLfsaT 429
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  94 VLEammvsaNLKLSEKQEVKKELvTEILTALGLMSCSHTRTAL----------LSGGQRKRLAIALELVNNPPVMFFDEP 163
Cdd:PRK11160  430 LRD------NLLLAAPNASDEAL-IEVLQQVGLEKLLEDDKGLnawlgeggrqLSGGEQRRLGIARALLHDAPLLLLDEP 502
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2462526932 164 TSGLDSASCFQVVSLMKSLAQgGRTIICTIHQpsAKLFEMFDKLYILSQGQCIFKG 219
Cdd:PRK11160  503 TEGLDAETERQILELLAEHAQ-NKTVLMITHR--LTGLEQFDRICVMDNGQIIEQG 555
cbiO PRK13643
energy-coupling factor transporter ATPase;
35-243 1.08e-14

energy-coupling factor transporter ATPase;


Pssm-ID: 184203 [Multi-domain]  Cd Length: 288  Bit Score: 74.77  E-value: 1.08e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  35 GIMGPSGAGKSTFMNILAGYRESGMK----GQILVNG--RPRELRTFRKMSCYIMQ--DDMLLPHLTVLEAMMVSANLKL 106
Cdd:PRK13643   36 ALIGHTGSGKSTLLQHLNGLLQPTEGkvtvGDIVVSStsKQKEIKPVRKKVGVVFQfpESQLFEETVLKDVAFGPQNFGI 115
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 107 SeKQEVKKeLVTEILTALGLMSCSHTRTAL-LSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKSLAQG 185
Cdd:PRK13643  116 P-KEKAEK-IAAEKLEMVGLADEFWEKSPFeLSGGQMRRVAIAGILAMEPEVLVLDEPTAGLDPKARIEMMQLFESIHQS 193
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462526932 186 GRTIICTIHQPSaKLFEMFDKLYILSQGQCIFKGVVTNL---IPYLKGLGLHCPTYHNPAD 243
Cdd:PRK13643  194 GQTVVLVTHLMD-DVADYADYVYLLEKGHIISCGTPSDVfqeVDFLKAHELGVPKATHFAD 253
anch_rpt_ABC TIGR03771
anchored repeat-type ABC transporter, ATP-binding subunit; This protein family is the ...
30-194 1.20e-14

anchored repeat-type ABC transporter, ATP-binding subunit; This protein family is the ATP-binding cassette subunit of binding protein-dependent ABC transporter complex that strictly co-occurs with TIGR03769. TIGRFAMs model TIGR03769 describes a protein domain that occurs singly or as one of up to three repeats in proteins of a number of Actinobacteria, including Propionibacterium acnes KPA171202. The TIGR03769 domain occurs both in an adjacent gene for the substrate-binding protein and in additional (often nearby) proteins, often with LPXTG-like sortase recognition signals. Homologous ATP-binding subunits outside the scope of this family include manganese transporter MntA in Synechocystis sp. PCC 6803 and chelated iron transporter subunits. The function of this transporter complex is unknown. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 163483 [Multi-domain]  Cd Length: 223  Bit Score: 73.35  E-value: 1.20e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  30 RRELIGIMGPSGAGKSTFMNILAGYRESGmKGQILVNGRPRelRTFRKMSCYIMQDDML---LPhLTVLEAMMVSANLKL 106
Cdd:TIGR03771   5 KGELLGLLGPNGAGKTTLLRAILGLIPPA-KGTVKVAGASP--GKGWRHIGYVPQRHEFawdFP-ISVAHTVMSGRTGHI 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 107 SEKQEVKKE---LVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKSLA 183
Cdd:TIGR03771  81 GWLRRPCVAdfaAVRDALRRVGLTELADRPVGELSGGQRQRVLVARALATRPSVLLLDEPFTGLDMPTQELLTELFIELA 160
                         170
                  ....*....|.
gi 2462526932 184 QGGRTIICTIH 194
Cdd:TIGR03771 161 GAGTAILMTTH 171
bacteriocin_ABC TIGR01193
ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The ...
32-227 1.27e-14

ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The amino terminal domain (pfam03412) processes the N-terminal leader peptide from the bacteriocin while C-terminal domains resemble ABC transporter membrane protein and ATP-binding cassette domain. In general, bacteriocins are agents which are responsible for killing or inhibiting the closely related species or even different strains of the same species. Bacteriocins are usually encoded by bacterial plasmids. Bacteriocins are named after the species and hence in literature one encounters various names e.g., leucocin from Leuconostic geldium; pedicocin from Pedicoccus acidilactici; sakacin from Lactobacillus sake etc. [Protein fate, Protein and peptide secretion and trafficking, Protein fate, Protein modification and repair, Transport and binding proteins, Other]


Pssm-ID: 130261 [Multi-domain]  Cd Length: 708  Bit Score: 77.09  E-value: 1.27e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  32 ELIGIMGPSGAGKSTFMNILAGYRESGmKGQILVNGRPR---ELRTFRKMSCYIMQDDMLLPHlTVLEAMMVSANLKLSE 108
Cdd:TIGR01193 501 SKTTIVGMSGSGKSTLAKLLVGFFQAR-SGEILLNGFSLkdiDRHTLRQFINYLPQEPYIFSG-SILENLLLGAKENVSQ 578
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 109 kQEVKKEL-VTEILTALGLMSCS-HTRTAL----LSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKSL 182
Cdd:TIGR01193 579 -DEIWAACeIAEIKDDIENMPLGyQTELSEegssISGGQKQRIALARALLTDSKVLILDESTSNLDTITEKKIVNNLLNL 657
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 2462526932 183 AQggRTIICTIHQPSakLFEMFDKLYILSQGQCIFKGVVTNLIPY 227
Cdd:TIGR01193 658 QD--KTIIFVAHRLS--VAKQSDKIIVLDHGKIIEQGSHDELLDR 698
cbiO PRK13647
cobalt transporter ATP-binding subunit; Provisional
21-219 1.54e-14

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237457 [Multi-domain]  Cd Length: 274  Bit Score: 74.00  E-value: 1.54e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  21 LKCLSGKFCRRELIGIMGPSGAGKSTFMNILAGYReSGMKGQILVNGR---PRELRTFRKMSCYIMQD-DMLLPHLTVLE 96
Cdd:PRK13647   21 LKGLSLSIPEGSKTALLGPNGAGKSTLLLHLNGIY-LPQRGRVKVMGRevnAENEKWVRSKVGLVFQDpDDQVFSSTVWD 99
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  97 AMMVSA-NLKLSeKQEVKkELVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQV 175
Cdd:PRK13647  100 DVAFGPvNMGLD-KDEVE-RRVEEALKAVRMWDFRDKPPYHLSYGQKKRVAIAGVLAMDPDVIVLDEPMAYLDPRGQETL 177
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 2462526932 176 VSLMKSLAQGGRTIICTIHQPSAKLfEMFDKLYILSQGQCIFKG 219
Cdd:PRK13647  178 MEILDRLHNQGKTVIVATHDVDLAA-EWADQVIVLKEGRVLAEG 220
PRK10070 PRK10070
proline/glycine betaine ABC transporter ATP-binding protein ProV;
32-219 2.01e-14

proline/glycine betaine ABC transporter ATP-binding protein ProV;


Pssm-ID: 182221 [Multi-domain]  Cd Length: 400  Bit Score: 75.45  E-value: 2.01e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  32 ELIGIMGPSGAGKSTFMNILAGYRESgMKGQILVNG---------RPRELRtfRKMSCYIMQDDMLLPHLTVLEAMMVSA 102
Cdd:PRK10070   55 EIFVIMGLSGSGKSTMVRLLNRLIEP-TRGQVLIDGvdiakisdaELREVR--RKKIAMVFQSFALMPHMTVLDNTAFGM 131
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 103 NLKLSEKQEvKKELVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVV-SLMKS 181
Cdd:PRK10070  132 ELAGINAEE-RREKALDALRQVGLENYAHSYPDELSGGMRQRVGLARALAINPDILLMDEAFSALDPLIRTEMQdELVKL 210
                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 2462526932 182 LAQGGRTIICTIHQPSAKLfEMFDKLYILSQGQCIFKG 219
Cdd:PRK10070  211 QAKHQRTIVFISHDLDEAM-RIGDRIAIMQNGEVVQVG 247
YejF COG4172
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ...
30-184 2.05e-14

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443332 [Multi-domain]  Cd Length: 533  Bit Score: 75.88  E-value: 2.05e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  30 RRELIGIMGPSGAGKSTFMNILAGYRESGmkGQILVNGRP------RELRTFRKMSCYIMQDDM--LLPHLTVL----EA 97
Cdd:COG4172   311 RGETLGLVGESGSGKSTLGLALLRLIPSE--GEIRFDGQDldglsrRALRPLRRRMQVVFQDPFgsLSPRMTVGqiiaEG 388
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  98 MMVSAnLKLSEKQevKKELVTEILTALGLmscshTRTAL------LSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSAS 171
Cdd:COG4172   389 LRVHG-PGLSAAE--RRARVAEALEEVGL-----DPAARhrypheFSGGQRQRIAIARALILEPKLLVLDEPTSALDVSV 460
                         170
                  ....*....|...
gi 2462526932 172 CFQVVSLMKSLAQ 184
Cdd:COG4172   461 QAQILDLLRDLQR 473
PRK03695 PRK03695
vitamin B12-transporter ATPase; Provisional
24-219 2.17e-14

vitamin B12-transporter ATPase; Provisional


Pssm-ID: 235150 [Multi-domain]  Cd Length: 248  Bit Score: 73.04  E-value: 2.17e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  24 LSGKFCRRELIGIMGPSGAGKSTFMNILAGYRESgmKGQILVNGRPRE---LRTFRKMSCYIMQDDMLLPHLTVLE--AM 98
Cdd:PRK03695   15 LSAEVRAGEILHLVGPNGAGKSTLLARMAGLLPG--SGSIQFAGQPLEawsAAELARHRAYLSQQQTPPFAMPVFQylTL 92
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  99 MVSANLKLSEKQEVkkelVTEILTALGLMSCSHTRTALLSGG--QRKRLAIALELV---NNP--PVMFFDEPTSGLDSAs 171
Cdd:PRK03695   93 HQPDKTRTEAVASA----LNEVAEALGLDDKLGRSVNQLSGGewQRVRLAAVVLQVwpdINPagQLLLLDEPMNSLDVA- 167
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2462526932 172 cfQVV---SLMKSLAQGGRTIICTIHQPSAKLfEMFDKLYILSQGQCIFKG 219
Cdd:PRK03695  168 --QQAaldRLLSELCQQGIAVVMSSHDLNHTL-RHADRVWLLKQGKLLASG 215
urea_trans_UrtE TIGR03410
urea ABC transporter, ATP-binding protein UrtE; Members of this protein family are ABC ...
32-224 2.67e-14

urea ABC transporter, ATP-binding protein UrtE; Members of this protein family are ABC transporter ATP-binding subunits associated with urea transport and metabolism. This protein is found in a conserved five-gene transport operon typically found adjacent to urease genes. It was shown in Cyanobacteria that disruption leads to the loss of high-affinity urea transport activity. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274567 [Multi-domain]  Cd Length: 230  Bit Score: 72.56  E-value: 2.67e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  32 ELIGIMGPSGAGKSTFMNILAGyRESGMKGQILVNGRPRE-LRTFRKMS---CYIMQDDMLLPHLTVLEAMMVSANLKLS 107
Cdd:TIGR03410  27 EVTCVLGRNGVGKTTLLKTLMG-LLPVKSGSIRLDGEDITkLPPHERARagiAYVPQGREIFPRLTVEENLLTGLAALPR 105
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 108 EKQEVKKELVtEILTALGLMScsHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGL------DSAscfQVVSLMKs 181
Cdd:TIGR03410 106 RSRKIPDEIY-ELFPVLKEML--GRRGGDLSGGQQQQLAIARALVTRPKLLLLDEPTEGIqpsiikDIG---RVIRRLR- 178
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 2462526932 182 lAQGGRTIIcTIHQPSAKLFEMFDKLYILSQGQCIFKGVVTNL 224
Cdd:TIGR03410 179 -AEGGMAIL-LVEQYLDFARELADRYYVMERGRVVASGAGDEL 219
LptB COG1137
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope ...
32-219 2.69e-14

ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440752 [Multi-domain]  Cd Length: 240  Bit Score: 72.75  E-value: 2.69e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  32 ELIGIMGPSGAGKSTFMNILAGyresgM----KGQILVNGR------------------PRELRTFRKMScyiMQDDMLL 89
Cdd:COG1137    30 EIVGLLGPNGAGKTTTFYMIVG-----LvkpdSGRIFLDGEdithlpmhkrarlgigylPQEASIFRKLT---VEDNILA 101
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  90 phltVLEAmmvsanLKLSEKQevKKELVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDS 169
Cdd:COG1137   102 ----VLEL------RKLSKKE--REERLEELLEEFGITHLRKSKAYSLSGGERRRVEIARALATNPKFILLDEPFAGVDP 169
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 2462526932 170 ASCFQVVSLMKSLAQGGRTIICTIHQPSAKLfEMFDKLYILSQGQCIFKG 219
Cdd:COG1137   170 IAVADIQKIIRHLKERGIGVLITDHNVRETL-GICDRAYIISEGKVLAEG 218
cbiO PRK13631
cobalt transporter ATP-binding subunit; Provisional
28-219 3.43e-14

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237451 [Multi-domain]  Cd Length: 320  Bit Score: 73.73  E-value: 3.43e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  28 FCRRELIGIMGPSGAGKSTFMNILAGYRESGmKGQILV----------------NGRPRELRTF---RKMSCYIMQ-DDM 87
Cdd:PRK13631   49 FEKNKIYFIIGNSGSGKSTLVTHFNGLIKSK-YGTIQVgdiyigdkknnhelitNPYSKKIKNFkelRRRVSMVFQfPEY 127
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  88 LLPHLTVLEAMMVSAnLKLSEKQEVKKELVTEILTALGLMSCSHTRTAL-LSGGQRKRLAIALELVNNPPVMFFDEPTSG 166
Cdd:PRK13631  128 QLFKDTIEKDIMFGP-VALGVKKSEAKKLAKFYLNKMGLDDSYLERSPFgLSGGQKRRVAIAGILAIQPEILIFDEPTAG 206
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2462526932 167 LDSASCFQVVSLMKSLAQGGRTIICTIHQpSAKLFEMFDKLYILSQGQCIFKG 219
Cdd:PRK13631  207 LDPKGEHEMMQLILDAKANNKTVFVITHT-MEHVLEVADEVIVMDKGKILKTG 258
ABCC_TAP cd03248
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; ...
32-175 4.18e-14

ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; TAP (Transporter Associated with Antigen Processing) is essential for peptide delivery from the cytosol into the lumen of the endoplasmic reticulum (ER), where these peptides are loaded on major histocompatibility complex (MHC) I molecules. Loaded MHC I leave the ER and display their antigenic cargo on the cell surface to cytotoxic T cells. Subsequently, virus-infected or malignantly transformed cells can be eliminated. TAP belongs to the large family of ATP-binding cassette (ABC) transporters, which translocate a vast variety of solutes across membranes.


Pssm-ID: 213215 [Multi-domain]  Cd Length: 226  Bit Score: 71.73  E-value: 4.18e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  32 ELIGIMGPSGAGKSTFMNILAGYRESgMKGQILVNGRPRELRTfrkmSCYIMQDDMLLPHLTVLEAMMVSANLKLSeKQE 111
Cdd:cd03248    41 EVTALVGPSGSGKSTVVALLENFYQP-QGGQVLLDGKPISQYE----HKYLHSKVSLVGQEPVLFARSLQDNIAYG-LQS 114
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2462526932 112 VKKELVTEI-----------LTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQV 175
Cdd:cd03248   115 CSFECVKEAaqkahahsfisELASGYDTEVGEKGSQLSGGQKQRVAIARALIRNPQVLILDEATSALDAESEQQV 189
NHLM_micro_ABC2 TIGR03797
NHLM bacteriocin system ABC transporter, ATP-binding protein; Members of this protein family ...
32-168 6.68e-14

NHLM bacteriocin system ABC transporter, ATP-binding protein; Members of this protein family are ABC transporter ATP-binding subunits, part of a three-gene putative bacteriocin transport operon. The other subunits include another ATP-binding subunit (TIGR03796), which has an N-terminal leader sequence cleavage domain, and an HlyD homolog (TIGR03794). In a number of genomes, members of protein families related to nitrile hydratase alpha subunit or to nif11 have undergone paralogous family expansions, with members possessing a putative bacteriocin cleavage region ending with a classic Gly-Gly motif. Those sets of putative bacteriocins, members of this protein family and its partners TIGR03794 and TIGR03796, and cyclodehydratase/docking scaffold fusion proteins of thiazole/oxazole biosynthesis frequently show correlated species distribution and co-clustering within many of those genomes. [Transport and binding proteins, Amino acids, peptides and amines, Cellular processes, Biosynthesis of natural products]


Pssm-ID: 274789 [Multi-domain]  Cd Length: 686  Bit Score: 74.61  E-value: 6.68e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  32 ELIGIMGPSGAGKSTFMNILAGYrESGMKGQILVNGRPRE---LRTFRKMSCYIMQDDMLLPHlTVLEAMMVSANLKLSE 108
Cdd:TIGR03797 480 EFVAIVGPSGSGKSTLLRLLLGF-ETPESGSVFYDGQDLAgldVQAVRRQLGVVLQNGRLMSG-SIFENIAGGAPLTLDE 557
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2462526932 109 KQEVKKEL-VTEILTAL--GLmscsHTRTA----LLSGGQRKRLAIALELVNNPPVMFFDEPTSGLD 168
Cdd:TIGR03797 558 AWEAARMAgLAEDIRAMpmGM----HTVISegggTLSGGQRQRLLIARALVRKPRILLFDEATSALD 620
ugpC PRK11650
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;
32-168 8.12e-14

sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;


Pssm-ID: 236947 [Multi-domain]  Cd Length: 356  Bit Score: 72.95  E-value: 8.12e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  32 ELIGIMGPSGAGKSTFMNILAGYrESGMKGQILVNGR------PRElrtfR--KMscyIMQDDMLLPHLTVLEAMmvSAN 103
Cdd:PRK11650   31 EFIVLVGPSGCGKSTLLRMVAGL-ERITSGEIWIGGRvvnelePAD----RdiAM---VFQNYALYPHMSVRENM--AYG 100
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2462526932 104 LKLS--EKQEVKKElVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLD 168
Cdd:PRK11650  101 LKIRgmPKAEIEER-VAEAARILELEPLLDRKPRELSGGQRQRVAMGRAIVREPAVFLFDEPLSNLD 166
PRK09700 PRK09700
D-allose ABC transporter ATP-binding protein AlsA;
8-214 9.72e-14

D-allose ABC transporter ATP-binding protein AlsA;


Pssm-ID: 182036 [Multi-domain]  Cd Length: 510  Bit Score: 73.67  E-value: 9.72e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932   8 FQKRIVASGYKTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAGYrESGMKGQILVNGR---PR-ELRTFRKMSCYIM 83
Cdd:PRK09700  266 FEVRNVTSRDRKKVRDISFSVCRGEILGFAGLVGSGRTELMNCLFGV-DKRAGGEIRLNGKdisPRsPLDAVKKGMAYIT 344
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  84 Q---DDMLLPHLTVLEAMMVSANLKLS----------EKQEVKKELVTEILTALGLMSCSHTRTALlSGGQRKRLAIALE 150
Cdd:PRK09700  345 EsrrDNGFFPNFSIAQNMAISRSLKDGgykgamglfhEVDEQRTAENQRELLALKCHSVNQNITEL-SGGNQQKVLISKW 423
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2462526932 151 LVNNPPVMFFDEPTSGLDSASCFQVVSLMKSLAQGGRTIICTihqpSAKLFEMF---DKLYILSQGQ 214
Cdd:PRK09700  424 LCCCPEVIIFDEPTRGIDVGAKAEIYKVMRQLADDGKVILMV----SSELPEIItvcDRIAVFCEGR 486
fbpC PRK11432
ferric ABC transporter ATP-binding protein;
30-169 1.05e-13

ferric ABC transporter ATP-binding protein;


Pssm-ID: 183133 [Multi-domain]  Cd Length: 351  Bit Score: 72.83  E-value: 1.05e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  30 RRELIGIMGPSGAGKSTFMNILAGYrESGMKGQILVNGrprELRTFRKMS----CYIMQDDMLLPHLTVLEAmmVSANLK 105
Cdd:PRK11432   31 QGTMVTLLGPSGCGKTTVLRLVAGL-EKPTEGQIFIDG---EDVTHRSIQqrdiCMVFQSYALFPHMSLGEN--VGYGLK 104
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2462526932 106 LS--EKQEVKKElVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDS 169
Cdd:PRK11432  105 MLgvPKEERKQR-VKEALELVDLAGFEDRYVDQISGGQQQRVALARALILKPKVLLFDEPLSNLDA 169
PhnL COG4778
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion ...
32-190 1.22e-13

Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion transport and metabolism];


Pssm-ID: 443809 [Multi-domain]  Cd Length: 229  Bit Score: 70.54  E-value: 1.22e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  32 ELIGIMGPSGAGKSTFMN-ILAGYRESGmkGQILVNGR----------PRE---LRtfRKMSCYIMQDDMLLPHLTVLEA 97
Cdd:COG4778    38 ECVALTGPSGAGKSTLLKcIYGNYLPDS--GSILVRHDggwvdlaqasPREilaLR--RRTIGYVSQFLRVIPRVSALDV 113
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  98 MMVSAnLKLSEKQEVKKELVTEILTALGLmscshtRTAL-------LSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSA 170
Cdd:COG4778   114 VAEPL-LERGVDREEARARARELLARLNL------PERLwdlppatFSGGEQQRVNIARGFIADPPLLLLDEPTASLDAA 186
                         170       180
                  ....*....|....*....|
gi 2462526932 171 SCFQVVSLMKSLAQGGRTII 190
Cdd:COG4778   187 NRAVVVELIEEAKARGTAII 206
type_I_sec_PrtD TIGR01842
type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in ...
32-214 1.25e-13

type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 200134 [Multi-domain]  Cd Length: 544  Bit Score: 73.54  E-value: 1.25e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  32 ELIGIMGPSGAGKSTFMNILAGYrESGMKGQILVNG---RPRELRTFRKMSCYIMQDDMLLPHlTV----------LEAM 98
Cdd:TIGR01842 345 EALAIIGPSGSGKSTLARLIVGI-WPPTSGSVRLDGadlKQWDRETFGKHIGYLPQDVELFPG-TVaeniarfgenADPE 422
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  99 MVSANLKLSEKQEVKKELVTEILTALGlmscshTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSL 178
Cdd:TIGR01842 423 KIIEAAKLAGVHELILRLPDGYDTVIG------PGGATLSGGQRQRIALARALYGDPKLVVLDEPNSNLDEEGEQALANA 496
                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 2462526932 179 MKSLAQGGRTIICTIHQPSakLFEMFDKLYILSQGQ 214
Cdd:TIGR01842 497 IKALKARGITVVVITHRPS--LLGCVDKILVLQDGR 530
ssuB PRK11247
aliphatic sulfonates transport ATP-binding subunit; Provisional
16-214 1.51e-13

aliphatic sulfonates transport ATP-binding subunit; Provisional


Pssm-ID: 183055 [Multi-domain]  Cd Length: 257  Bit Score: 70.86  E-value: 1.51e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  16 GYKTLLKCL-----SGKFcrrelIGIMGPSGAGKSTFMNILAGYrESGMKGQILVNGRPreLRTFRKMSCYIMQDDMLLP 90
Cdd:PRK11247   23 GERTVLNQLdlhipAGQF-----VAVVGRSGCGKSTLLRLLAGL-ETPSAGELLAGTAP--LAEAREDTRLMFQDARLLP 94
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  91 HLTVLEammvsaNLKLSEKQEVKKElVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSA 170
Cdd:PRK11247   95 WKKVID------NVGLGLKGQWRDA-ALQALAAVGLADRANEWPAALSGGQKQRVALARALIHRPGLLLLDEPLGALDAL 167
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 2462526932 171 SCFQVVSLMKSL-AQGGRTIICTIHQPSAKLfEMFDKLYILSQGQ 214
Cdd:PRK11247  168 TRIEMQDLIESLwQQHGFTVLLVTHDVSEAV-AMADRVLLIEEGK 211
PhnK COG1101
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
32-168 2.05e-13

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 440718 [Multi-domain]  Cd Length: 264  Bit Score: 70.50  E-value: 2.05e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  32 ELIGIMGPSGAGKSTFMNILAG-YRESGmkGQILVNGR-----PRELRtfrkmSCYI---MQDDML--LPHLTVLEAMMV 100
Cdd:COG1101    33 DFVTVIGSNGAGKSTLLNAIAGsLPPDS--GSILIDGKdvtklPEYKR-----AKYIgrvFQDPMMgtAPSMTIEENLAL 105
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2462526932 101 SAN------LKLSEKQEvKKELVTEILTALGL-----MscsHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLD 168
Cdd:COG1101   106 AYRrgkrrgLRRGLTKK-RRELFRELLATLGLglenrL---DTKVGLLSGGQRQALSLLMATLTKPKLLLLDEHTAALD 180
ABC_Carb_Monos_II cd03215
Second domain of the ATP-binding cassette component of monosaccharide transport system; This ...
29-190 2.20e-13

Second domain of the ATP-binding cassette component of monosaccharide transport system; This family represents domain II of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. In members of Carb_Monos family the single hydrophobic gene product forms a homodimer, while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.


Pssm-ID: 213182 [Multi-domain]  Cd Length: 182  Bit Score: 68.61  E-value: 2.20e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  29 CRRELIGIMGPSGAGKSTFMNILAGYReSGMKGQILVNGRPRELRTFRKMS----CYIMQD---DMLLPHLTVLEammvs 101
Cdd:cd03215    24 RAGEIVGIAGLVGNGQTELAEALFGLR-PPASGEITLDGKPVTRRSPRDAIragiAYVPEDrkrEGLVLDLSVAE----- 97
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 102 aNLKLSekqevkkelvteiltalglmscshtrtALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKS 181
Cdd:cd03215    98 -NIALS---------------------------SLLSGGNQQKVVLARWLARDPRVLILDEPTRGVDVGAKAEIYRLIRE 149

                  ....*....
gi 2462526932 182 LAQGGRTII 190
Cdd:cd03215   150 LADAGKAVL 158
Uup COG0488
ATPase components of ABC transporters with duplicated ATPase domains [General function ...
18-168 4.42e-13

ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];


Pssm-ID: 440254 [Multi-domain]  Cd Length: 520  Bit Score: 71.63  E-value: 4.42e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  18 KTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAGyRESGMKGQI-----LVNGrprelrtfrkmscYIMQD-DMLLPH 91
Cdd:COG0488   328 KTLLDDLSLRIDRGDRIGLIGPNGAGKSTLLKLLAG-ELEPDSGTVklgetVKIG-------------YFDQHqEELDPD 393
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  92 LTVLEAMmvsanlklseKQEVKKELVTEILTALGLM----SCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGL 167
Cdd:COG0488   394 KTVLDEL----------RDGAPGGTEQEVRGYLGRFlfsgDDAFKPVGVLSGGEKARLALAKLLLSPPNVLLLDEPTNHL 463

                  .
gi 2462526932 168 D 168
Cdd:COG0488   464 D 464
cbiO PRK13637
energy-coupling factor transporter ATPase;
31-238 4.47e-13

energy-coupling factor transporter ATPase;


Pssm-ID: 237455 [Multi-domain]  Cd Length: 287  Bit Score: 70.08  E-value: 4.47e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  31 RELIGIMGPSGAGKSTFMNILAGYRESgMKGQILVNG-----RPRELRTFRKMSCYIMQddmlLPHLTVLEAMMVS---- 101
Cdd:PRK13637   33 GEFVGLIGHTGSGKSTLIQHLNGLLKP-TSGKIIIDGvditdKKVKLSDIRKKVGLVFQ----YPEYQLFEETIEKdiaf 107
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 102 --ANLKLSEkQEVKKElVTEILTALGL-MSCSHTRTAL-LSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVS 177
Cdd:PRK13637  108 gpINLGLSE-EEIENR-VKRAMNIVGLdYEDYKDKSPFeLSGGQKRRVAIAGVVAMEPKILILDEPTAGLDPKGRDEILN 185
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2462526932 178 LMKSLAQG-GRTIICTIH--QPSAKLfemFDKLYILSQGQCIFKGV---VTNLIPYLKGLGLHCP--TY 238
Cdd:PRK13637  186 KIKELHKEyNMTIILVSHsmEDVAKL---ADRIIVMNKGKCELQGTpreVFKEVETLESIGLAVPqvTY 251
PRK14267 PRK14267
phosphate ABC transporter ATP-binding protein; Provisional
13-197 5.80e-13

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 184596 [Multi-domain]  Cd Length: 253  Bit Score: 69.10  E-value: 5.80e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  13 VASGYKTLLKCLSGKFCRRELIGIMGPSGAGKST----FMNILAGYRESGMKGQILVNGR--------PRELRTFRKMsc 80
Cdd:PRK14267   12 VYYGSNHVIKGVDLKIPQNGVFALMGPSGCGKSTllrtFNRLLELNEEARVEGEVRLFGRniyspdvdPIEVRREVGM-- 89
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  81 yIMQDDMLLPHLTVLEAmmVSANLKLSEKQEVKKELVTEILTAL---GLMSCSHTR----TALLSGGQRKRLAIALELVN 153
Cdd:PRK14267   90 -VFQYPNPFPHLTIYDN--VAIGVKLNGLVKSKKELDERVEWALkkaALWDEVKDRlndyPSNLSGGQRQRLVIARALAM 166
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 2462526932 154 NPPVMFFDEPTSGLDSASCFQVVSLMKSLAQgGRTIICTIHQPS 197
Cdd:PRK14267  167 KPKILLMDEPTANIDPVGTAKIEELLFELKK-EYTIVLVTHSPA 209
COG4586 COG4586
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
32-225 6.51e-13

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 443643 [Multi-domain]  Cd Length: 323  Bit Score: 69.73  E-value: 6.51e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  32 ELIGIMGPSGAGKSTFMNILAG--YRESGmkgQILVNGR-P-RELRTFRKMSCYIM-QDDMLLPHLTVLEammvSANL-- 104
Cdd:COG4586    49 EIVGFIGPNGAGKSTTIKMLTGilVPTSG---EVRVLGYvPfKRRKEFARRIGVVFgQRSQLWWDLPAID----SFRLlk 121
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 105 ---KLSEKqEVKKEL--VTEILTALGLMscsHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLM 179
Cdd:COG4586   122 aiyRIPDA-EYKKRLdeLVELLDLGELL---DTPVRQLSLGQRMRCELAAALLHRPKILFLDEPTIGLDVVSKEAIREFL 197
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2462526932 180 KSL-AQGGRTIICTIHqpsaklfEMFD------KLYILSQGQCIFKGVVTNLI 225
Cdd:COG4586   198 KEYnRERGTTILLTSH-------DMDDiealcdRVIVIDHGRIIYDGSLEELK 243
btuD PRK09536
corrinoid ABC transporter ATPase; Reviewed
30-194 1.02e-12

corrinoid ABC transporter ATPase; Reviewed


Pssm-ID: 236554 [Multi-domain]  Cd Length: 402  Bit Score: 70.26  E-value: 1.02e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  30 RRELIGIMGPSGAGKSTFMNILAGYRESGmKGQILVNGRPRELRTFRKMSCYIM---QDDML--------------LPHL 92
Cdd:PRK09536   28 EGSLVGLVGPNGAGKTTLLRAINGTLTPT-AGTVLVAGDDVEALSARAASRRVAsvpQDTSLsfefdvrqvvemgrTPHR 106
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  93 TvleammvsanlKLSEKQEVKKELVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASC 172
Cdd:PRK09536  107 S-----------RFDTWTETDRAAVERAMERTGVAQFADRPVTSLSGGERQRVLLARALAQATPVLLLDEPTASLDINHQ 175
                         170       180
                  ....*....|....*....|..
gi 2462526932 173 FQVVSLMKSLAQGGRTIICTIH 194
Cdd:PRK09536  176 VRTLELVRRLVDDGKTAVAAIH 197
livG PRK11300
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional
30-168 1.04e-12

leucine/isoleucine/valine transporter ATP-binding subunit; Provisional


Pssm-ID: 183080 [Multi-domain]  Cd Length: 255  Bit Score: 68.48  E-value: 1.04e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  30 RRELIGIMGPSGAGKSTFMNILAG-YRESGmkGQILVNGRPRE------------LRTFrkmscyimQDDMLLPHLTVLE 96
Cdd:PRK11300   30 EQEIVSLIGPNGAGKTTVFNCLTGfYKPTG--GTILLRGQHIEglpghqiarmgvVRTF--------QHVRLFREMTVIE 99
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  97 AMMVSANLKL----------------SEKQEVkkELVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFF 160
Cdd:PRK11300  100 NLLVAQHQQLktglfsgllktpafrrAESEAL--DRAATWLERVGLLEHANRQAGNLAYGQQRRLEIARCMVTQPEILML 177

                  ....*...
gi 2462526932 161 DEPTSGLD 168
Cdd:PRK11300  178 DEPAAGLN 185
PRK15079 PRK15079
oligopeptide ABC transporter ATP-binding protein OppF; Provisional
32-182 1.20e-12

oligopeptide ABC transporter ATP-binding protein OppF; Provisional


Pssm-ID: 185037 [Multi-domain]  Cd Length: 331  Bit Score: 69.35  E-value: 1.20e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  32 ELIGIMGPSGAGKSTFMNILAGYRESgMKGQILVNGR------PRELRTFRKMSCYIMQDDM--LLPHLTVLEamMVSAN 103
Cdd:PRK15079   48 ETLGVVGESGCGKSTFARAIIGLVKA-TDGEVAWLGKdllgmkDDEWRAVRSDIQMIFQDPLasLNPRMTIGE--IIAEP 124
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 104 L-----KLSeKQEVKKElVTEILTALGLMSCSHTRTAL-LSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVS 177
Cdd:PRK15079  125 LrtyhpKLS-RQEVKDR-VKAMMLKVGLLPNLINRYPHeFSGGQCQRIGIARALILEPKLIICDEPVSALDVSIQAQVVN 202

                  ....*
gi 2462526932 178 LMKSL 182
Cdd:PRK15079  203 LLQQL 207
xylG TIGR02633
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ...
30-214 1.26e-12

D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 131681 [Multi-domain]  Cd Length: 500  Bit Score: 70.24  E-value: 1.26e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  30 RRELIGIMGPSGAGKSTFMNILAGYRESGMKGQILVNGRPRELRT----FRKMSCYIMQD---DMLLPHLTVLEAMMVSA 102
Cdd:TIGR02633 285 RGEILGVAGLVGAGRTELVQALFGAYPGKFEGNVFINGKPVDIRNpaqaIRAGIAMVPEDrkrHGIVPILGVGKNITLSV 364
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 103 NLKLSEKQEVKKElvTEILTALGLMSCSHTRTAL-------LSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQV 175
Cdd:TIGR02633 365 LKSFCFKMRIDAA--AELQIIGSAIQRLKVKTASpflpigrLSGGNQQKAVLAKMLLTNPRVLILDEPTRGVDVGAKYEI 442
                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 2462526932 176 VSLMKSLAQGGRTIIcTIHQPSAKLFEMFDKLYILSQGQ 214
Cdd:TIGR02633 443 YKLINQLAQEGVAII-VVSSELAEVLGLSDRVLVIGEGK 480
SufC COG0396
Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, ...
32-214 1.40e-12

Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440165 [Multi-domain]  Cd Length: 245  Bit Score: 67.78  E-value: 1.40e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  32 ELIGIMGPSGAGKSTFMNILAG---YRESGmkGQILVNG----------RPRE-LrtFrkmscYIMQDDMLLPHLTVLEA 97
Cdd:COG0396    27 EVHAIMGPNGSGKSTLAKVLMGhpkYEVTS--GSILLDGedilelspdeRARAgI--F-----LAFQYPVEIPGVSVSNF 97
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  98 MMVSANLKLSEKQEVKK--ELVTEILTALGlMSCSHTRTAL---LSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASc 172
Cdd:COG0396    98 LRTALNARRGEELSAREflKLLKEKMKELG-LDEDFLDRYVnegFSGGEKKRNEILQMLLLEPKLAILDETDSGLDIDA- 175
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 2462526932 173 FQVVS-LMKSLAQGGRTIICTIHQPsaKLFEMF--DKLYILSQGQ 214
Cdd:COG0396   176 LRIVAeGVNKLRSPDRGILIITHYQ--RILDYIkpDFVHVLVDGR 218
nikE PRK10419
nickel ABC transporter ATP-binding protein NikE;
14-184 1.70e-12

nickel ABC transporter ATP-binding protein NikE;


Pssm-ID: 236689 [Multi-domain]  Cd Length: 268  Bit Score: 67.79  E-value: 1.70e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  14 ASGYKTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAGYrESGMKGQILVNGRP------RELRTFRKMSCYIMQDDM 87
Cdd:PRK10419   21 KHQHQTVLNNVSLSLKSGETVALLGRSGCGKSTLARLLVGL-ESPSQGNVSWRGEPlaklnrAQRKAFRRDIQMVFQDSI 99
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  88 --LLPHLTV----LEAMMVSANLKLSEKQEVKKELVTEILTALGLMScshTRTALLSGGQRKRLAIALELVNNPPVMFFD 161
Cdd:PRK10419  100 saVNPRKTVreiiREPLRHLLSLDKAERLARASEMLRAVDLDDSVLD---KRPPQLSGGQLQRVCLARALAVEPKLLILD 176
                         170       180
                  ....*....|....*....|...
gi 2462526932 162 EPTSGLDSASCFQVVSLMKSLAQ 184
Cdd:PRK10419  177 EAVSNLDLVLQAGVIRLLKKLQQ 199
sufC TIGR01978
FeS assembly ATPase SufC; SufC is part of the SUF system, shown in E. coli to consist of six ...
32-219 2.72e-12

FeS assembly ATPase SufC; SufC is part of the SUF system, shown in E. coli to consist of six proteins and believed to act in Fe-S cluster formation during oxidative stress. SufC forms a complex with SufB and SufD. SufC belongs to the ATP-binding cassette transporter family (pfam00005) but is no longer thought to be part of a transporter. The complex is reported as cytosolic () or associated with the membrane (). The SUF system also includes a cysteine desulfurase (SufS, enhanced by SufE) and a probable iron-sulfur cluster assembly scaffold protein, SufA. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other]


Pssm-ID: 273907 [Multi-domain]  Cd Length: 243  Bit Score: 66.90  E-value: 2.72e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  32 ELIGIMGPSGAGKSTFMNILAG---YRESG----MKGQILVNGRPRElRTfRKMSCYIMQDDMLLPHLTVLEAMMVSANL 104
Cdd:TIGR01978  27 EIHAIMGPNGSGKSTLSKTIAGhpsYEVTSgtilFKGQDLLELEPDE-RA-RAGLFLAFQYPEEIPGVSNLEFLRSALNA 104
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 105 KLSEKQEVK------KELVTEILTALGlMSCSHTRTAL---LSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQV 175
Cdd:TIGR01978 105 RRSARGEEPldlldfEKLLKEKLALLD-MDEEFLNRSVnegFSGGEKKRNEILQMALLEPKLAILDEIDSGLDIDALKIV 183
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 2462526932 176 VSLMKSLAQGGRTIICTIHQPsaKLFEMF--DKLYILSQGQCIFKG 219
Cdd:TIGR01978 184 AEGINRLREPDRSFLIITHYQ--RLLNYIkpDYVHVLLDGRIVKSG 227
PRK13651 PRK13651
cobalt transporter ATP-binding subunit; Provisional
32-194 5.82e-12

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184210 [Multi-domain]  Cd Length: 305  Bit Score: 66.65  E-value: 5.82e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  32 ELIGIMGPSGAGKSTF---MNIL--------------------AGYRESGMKGQILVNGRPRELRT---FRKMSCYIMQ- 84
Cdd:PRK13651   34 EFIAIIGQTGSGKTTFiehLNALllpdtgtiewifkdeknkkkTKEKEKVLEKLVIQKTRFKKIKKikeIRRRVGVVFQf 113
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  85 DDMLLPHLTVLEAMMVSANLKLSEKQEVKKeLVTEILTALGLMSCSHTRTAL-LSGGQRKRLAIALELVNNPPVMFFDEP 163
Cdd:PRK13651  114 AEYQLFEQTIEKDIIFGPVSMGVSKEEAKK-RAAKYIELVGLDESYLQRSPFeLSGGQKRRVALAGILAMEPDFLVFDEP 192
                         170       180       190
                  ....*....|....*....|....*....|.
gi 2462526932 164 TSGLDSASCFQVVSLMKSLAQGGRTIICTIH 194
Cdd:PRK13651  193 TAGLDPQGVKEILEIFDNLNKQGKTIILVTH 223
PstB COG1117
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; ...
27-190 7.70e-12

ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440734 [Multi-domain]  Cd Length: 258  Bit Score: 65.83  E-value: 7.70e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  27 KFCRRELIGIMGPSGAGKSTF------MNIL-AGYResgMKGQILVNGR--------PRELRT-----FRK-----MSCY 81
Cdd:COG1117    33 DIPENKVTALIGPSGCGKSTLlrclnrMNDLiPGAR---VEGEILLDGEdiydpdvdVVELRRrvgmvFQKpnpfpKSIY 109
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  82 imqDDmllphltvleammVSANLKLSE--KQEVKKELVTEILTALGL---------MScshtrtAL-LSGGQRKRLAIAL 149
Cdd:COG1117   110 ---DN-------------VAYGLRLHGikSKSELDEIVEESLRKAALwdevkdrlkKS------ALgLSGGQQQRLCIAR 167
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 2462526932 150 ELVNNPPVMFFDEPTSGLDSASCFQVVSLMKSLAQgGRTII 190
Cdd:COG1117   168 ALAVEPEVLLMDEPTSALDPISTAKIEELILELKK-DYTIV 207
3a01208 TIGR00958
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]
32-224 8.30e-12

Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273363 [Multi-domain]  Cd Length: 711  Bit Score: 68.21  E-value: 8.30e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  32 ELIGIMGPSGAGKSTFMNILAGYRESgMKGQILVNGRPreLRTFRkmSCYIMQDDMLLPHLTVLEAMMVSAN----LKLS 107
Cdd:TIGR00958 508 EVVALVGPSGSGKSTVAALLQNLYQP-TGGQVLLDGVP--LVQYD--HHYLHRQVALVGQEPVLFSGSVRENiaygLTDT 582
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 108 EKQEVkkelvteilTALGLMSCSHT---------------RTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASC 172
Cdd:TIGR00958 583 PDEEI---------MAAAKAANAHDfimefpngydtevgeKGSQLSGGQKQRIAIARALVRKPRVLILDEATSALDAECE 653
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2462526932 173 FQVVSLMKslaQGGRTIICTIHQPSakLFEMFDKLYILSQGQCIFKGVVTNL 224
Cdd:TIGR00958 654 QLLQESRS---RASRTVLLIAHRLS--TVERADQILVLKKGSVVEMGTHKQL 700
cbiO PRK13649
energy-coupling factor transporter ATPase;
37-219 1.38e-11

energy-coupling factor transporter ATPase;


Pssm-ID: 184208 [Multi-domain]  Cd Length: 280  Bit Score: 65.54  E-value: 1.38e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  37 MGPSGAGKSTFMNILAGYReSGMKGQILVNG-------RPRELRTFRKMSCYIMQ-DDMLLPHLTVLEAMMVSA-NLKLS 107
Cdd:PRK13649   39 IGHTGSGKSTIMQLLNGLH-VPTQGSVRVDDtlitstsKNKDIKQIRKKVGLVFQfPESQLFEETVLKDVAFGPqNFGVS 117
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 108 EKQEVKkeLVTEILTALGLMSCSHTRTAL-LSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKSLAQGG 186
Cdd:PRK13649  118 QEEAEA--LAREKLALVGISESLFEKNPFeLSGGQMRRVAIAGILAMEPKILVLDEPTAGLDPKGRKELMTLFKKLHQSG 195
                         170       180       190
                  ....*....|....*....|....*....|...
gi 2462526932 187 RTIICTIHQPSaKLFEMFDKLYILSQGQCIFKG 219
Cdd:PRK13649  196 MTIVLVTHLMD-DVANYADFVYVLEKGKLVLSG 227
cbiO PRK13632
cobalt transporter ATP-binding subunit; Provisional
18-219 1.54e-11

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237452 [Multi-domain]  Cd Length: 271  Bit Score: 65.01  E-value: 1.54e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  18 KTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAG-YRESgmKGQILVNG---RPRELRTFRKMSCYIMQD-DMLLPHL 92
Cdd:PRK13632   22 NNALKNVSFEINEGEYVAILGHNGSGKSTISKILTGlLKPQ--SGEIKIDGitiSKENLKEIRKKIGIIFQNpDNQFIGA 99
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  93 TV-------LEAMMVSanlklsekQEVKKELVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTS 165
Cdd:PRK13632  100 TVeddiafgLENKKVP--------PKKMKDIIDDLAKKVGMEDYLDKEPQNLSGGQKQRVAIASVLALNPEIIIFDESTS 171
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2462526932 166 GLDSASCFQVVSLMKSLA-QGGRTIICTIHQPSAKLfeMFDKLYILSQGQCIFKG 219
Cdd:PRK13632  172 MLDPKGKREIKKIMVDLRkTRKKTLISITHDMDEAI--LADKVIVFSEGKLIAQG 224
PRK14258 PRK14258
phosphate ABC transporter ATP-binding protein; Provisional
18-243 1.67e-11

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 184593 [Multi-domain]  Cd Length: 261  Bit Score: 64.67  E-value: 1.67e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  18 KTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAgyRESGMKGQILVNGRPR-----------ELRTFRKMSCYIMQDD 86
Cdd:PRK14258   20 QKILEGVSMEIYQSKVTAIIGPSGCGKSTFLKCLN--RMNELESEVRVEGRVEffnqniyerrvNLNRLRRQVSMVHPKP 97
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  87 MLLPhLTVLEAMMVSANL----------KLSEKQEVKKELVTEILTALglmscsHTRTALLSGGQRKRLAIALELVNNPP 156
Cdd:PRK14258   98 NLFP-MSVYDNVAYGVKIvgwrpkleidDIVESALKDADLWDEIKHKI------HKSALDLSGGQQQRLCIARALAVKPK 170
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 157 VMFFDEPTSGLDSASCFQVVSLMKSLA-QGGRTIICTIHQpsaklfemFDKLYILSQGQCIFKGvVTNLIPYLKGLGLHC 235
Cdd:PRK14258  171 VLLMDEPCFGLDPIASMKVESLIQSLRlRSELTMVIVSHN--------LHQVSRLSDFTAFFKG-NENRIGQLVEFGLTK 241

                  ....*...
gi 2462526932 236 PTYHNPAD 243
Cdd:PRK14258  242 KIFNSPHD 249
PRK15056 PRK15056
manganese/iron ABC transporter ATP-binding protein;
36-194 2.39e-11

manganese/iron ABC transporter ATP-binding protein;


Pssm-ID: 185016 [Multi-domain]  Cd Length: 272  Bit Score: 64.52  E-value: 2.39e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  36 IMGPSGAGKSTFMNILAGYRESGmKGQILVNGRPRELRTFRKMSCYIMQD---DMLLPHLTVLEAMMVSAN----LKLSE 108
Cdd:PRK15056   38 LVGVNGSGKSTLFKALMGFVRLA-SGKISILGQPTRQALQKNLVAYVPQSeevDWSFPVLVEDVVMMGRYGhmgwLRRAK 116
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 109 KQEvkKELVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKSLAQGGRT 188
Cdd:PRK15056  117 KRD--RQIVTAALARVDMVEFRHRQIGELSGGQKKRVFLARAIAQQGQVILLDEPFTGVDVKTEARIISLLRELRDEGKT 194

                  ....*.
gi 2462526932 189 IICTIH 194
Cdd:PRK15056  195 MLVSTH 200
cbiO PRK13646
energy-coupling factor transporter ATPase;
36-224 2.40e-11

energy-coupling factor transporter ATPase;


Pssm-ID: 184205 [Multi-domain]  Cd Length: 286  Bit Score: 64.80  E-value: 2.40e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  36 IMGPSGAGKSTFMNILAGYRESgMKGQILVNG-------RPRELRTFRKMSCYIMQ--DDMLLPHLTVLEAMMVSANLKL 106
Cdd:PRK13646   38 IVGQTGSGKSTLIQNINALLKP-TTGTVTVDDitithktKDKYIRPVRKRIGMVFQfpESQLFEDTVEREIIFGPKNFKM 116
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 107 SEKQevKKELVTEILTALG----LMSCSHTRtalLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKSL 182
Cdd:PRK13646  117 NLDE--VKNYAHRLLMDLGfsrdVMSQSPFQ---MSGGQMRKIAIVSILAMNPDIIVLDEPTAGLDPQSKRQVMRLLKSL 191
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 2462526932 183 A-QGGRTIICTIHQPSaKLFEMFDKLYILSQGQCIFKGVVTNL 224
Cdd:PRK13646  192 QtDENKTIILVSHDMN-EVARYADEVIVMKEGSIVSQTSPKEL 233
met_CoM_red_A2 TIGR03269
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ...
31-194 3.24e-11

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]


Pssm-ID: 132313 [Multi-domain]  Cd Length: 520  Bit Score: 65.98  E-value: 3.24e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  31 RELIGIMGPSGAGKSTFMNILAGYRESgMKGQILV--------------NGRPRELRtfrkmscYI---MQDDMLLPHLT 93
Cdd:TIGR03269 310 GEIFGIVGTSGAGKTTLSKIIAGVLEP-TSGEVNVrvgdewvdmtkpgpDGRGRAKR-------YIgilHQEYDLYPHRT 381
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  94 VLEAMMVSANLKLSEKQEVKKELVTeiLTALGLmSCSHTRTAL------LSGGQRKRLAIALELVNNPPVMFFDEPTSGL 167
Cdd:TIGR03269 382 VLDNLTEAIGLELPDELARMKAVIT--LKMVGF-DEEKAEEILdkypdeLSEGERHRVALAQVLIKEPRIVILDEPTGTM 458
                         170       180
                  ....*....|....*....|....*...
gi 2462526932 168 DSASCFQVV-SLMKSLAQGGRTIICTIH 194
Cdd:TIGR03269 459 DPITKVDVThSILKAREEMEQTFIIVSH 486
CeuD COG4604
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and ...
36-194 4.16e-11

ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443654 [Multi-domain]  Cd Length: 252  Bit Score: 63.56  E-value: 4.16e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  36 IMGPSGAGKSTFMNILAgyRESGM-KGQILVNGRP------RELRtfRKMScyIM-QDDMLLPHLTVLEamMVS------ 101
Cdd:COG4604    32 LIGPNGAGKSTLLSMIS--RLLPPdSGEVLVDGLDvattpsRELA--KRLA--ILrQENHINSRLTVRE--LVAfgrfpy 103
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 102 ANLKLSEKQEvkkELVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKS 181
Cdd:COG4604   104 SKGRLTAEDR---EIIDEAIAYLDLEDLADRYLDELSGGQRQRAFIAMVLAQDTDYVLLDEPLNNLDMKHSVQMMKLLRR 180
                         170
                  ....*....|....
gi 2462526932 182 LAQG-GRTIICTIH 194
Cdd:COG4604   181 LADElGKTVVIVLH 194
PRK11831 PRK11831
phospholipid ABC transporter ATP-binding protein MlaF;
30-224 4.25e-11

phospholipid ABC transporter ATP-binding protein MlaF;


Pssm-ID: 236997 [Multi-domain]  Cd Length: 269  Bit Score: 63.63  E-value: 4.25e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  30 RRELIGIMGPSGAGKSTFMNILAGYRESGmKGQILVNG-------RPRELRTFRKMScYIMQDDMLLPHLTVLE--AMMV 100
Cdd:PRK11831   32 RGKITAIMGPSGIGKTTLLRLIGGQIAPD-HGEILFDGenipamsRSRLYTVRKRMS-MLFQSGALFTDMNVFDnvAYPL 109
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 101 SANLKLSEkqEVKKELVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMK 180
Cdd:PRK11831  110 REHTQLPA--PLLHSTVMMKLEAVGLRGAAKLMPSELSGGMARRAALARAIALEPDLIMFDEPFVGQDPITMGVLVKLIS 187
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 2462526932 181 SLAQG-GRTIICTIHQpSAKLFEMFDKLYILSQGQCIFKGVVTNL 224
Cdd:PRK11831  188 ELNSAlGVTCVVVSHD-VPEVLSIADHAYIVADKKIVAHGSAQAL 231
PRK13657 PRK13657
glucan ABC transporter ATP-binding protein/ permease;
32-213 4.41e-11

glucan ABC transporter ATP-binding protein/ permease;


Pssm-ID: 184214 [Multi-domain]  Cd Length: 588  Bit Score: 65.75  E-value: 4.41e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  32 ELIGIMGPSGAGKSTFMNILAGYRESgMKGQILVNG---RPRELRTFRKMSCYIMQDDMLL------------PHLT--- 93
Cdd:PRK13657  362 QTVAIVGPTGAGKSTLINLLQRVFDP-QSGRILIDGtdiRTVTRASLRRNIAVVFQDAGLFnrsiednirvgrPDATdee 440
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  94 VLEAMMVSANLKLSEKQEVKKElvteilTALGlmscshTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCF 173
Cdd:PRK13657  441 MRAAAERAQAHDFIERKPDGYD------TVVG------ERGRQLSGGERQRLAIARALLKDPPILILDEATSALDVETEA 508
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 2462526932 174 QVVSLMKSLAQgGRTIICTIHQPS----AKLFEMFDKLYILSQG 213
Cdd:PRK13657  509 KVKAALDELMK-GRTTFIIAHRLStvrnADRILVFDNGRVVESG 551
MglA COG1129
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
32-190 4.46e-11

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440745 [Multi-domain]  Cd Length: 497  Bit Score: 65.42  E-value: 4.46e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  32 ELIGIMGPSGAGKSTFMNILAG--YRESGmkgQILVNGRPRELRTFRKMS----CYIMQD---DMLLPHLTVLEAMMVsA 102
Cdd:COG1129   279 EILGIAGLVGAGRTELARALFGadPADSG---EIRLDGKPVRIRSPRDAIragiAYVPEDrkgEGLVLDLSIRENITL-A 354
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 103 NLK-------LSEKQEvkKELVTEILTALGL-MSCSHTRTALLSGG-QRKrLAIALELVNNPPVMFFDEPTSGLDSASCF 173
Cdd:COG1129   355 SLDrlsrgglLDRRRE--RALAEEYIKRLRIkTPSPEQPVGNLSGGnQQK-VVLAKWLATDPKVLILDEPTRGIDVGAKA 431
                         170
                  ....*....|....*..
gi 2462526932 174 QVVSLMKSLAQGGRTII 190
Cdd:COG1129   432 EIYRLIRELAAEGKAVI 448
cbiO PRK13641
energy-coupling factor transporter ATPase;
22-194 7.05e-11

energy-coupling factor transporter ATPase;


Pssm-ID: 237456 [Multi-domain]  Cd Length: 287  Bit Score: 63.31  E-value: 7.05e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  22 KCLSGKFcrrelIGIMGPSGAGKSTFM---NIL----------AGYresgmkgQILVNGRPRELRTFRKMSCYIMQ-DDM 87
Cdd:PRK13641   29 ELEEGSF-----VALVGHTGSGKSTLMqhfNALlkpssgtitiAGY-------HITPETGNKNLKKLRKKVSLVFQfPEA 96
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  88 LLPHLTVLEAMMVSA-NLKLSEKQevKKELVTEILTALGLMSCSHTRTAL-LSGGQRKRLAIALELVNNPPVMFFDEPTS 165
Cdd:PRK13641   97 QLFENTVLKDVEFGPkNFGFSEDE--AKEKALKWLKKVGLSEDLISKSPFeLSGGQMRRVAIAGVMAYEPEILCLDEPAA 174
                         170       180
                  ....*....|....*....|....*....
gi 2462526932 166 GLDSASCFQVVSLMKSLAQGGRTIICTIH 194
Cdd:PRK13641  175 GLDPEGRKEMMQLFKDYQKAGHTVILVTH 203
PRK09700 PRK09700
D-allose ABC transporter ATP-binding protein AlsA;
32-224 7.07e-11

D-allose ABC transporter ATP-binding protein AlsA;


Pssm-ID: 182036 [Multi-domain]  Cd Length: 510  Bit Score: 64.81  E-value: 7.07e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  32 ELIGIMGPSGAGKSTFMNILAGYRESgMKGQILVNGRPRElRTFRKMSC-----YIMQDDMLLPHLTVLEAMMVSanlKL 106
Cdd:PRK09700   32 EIHALLGENGAGKSTLMKVLSGIHEP-TKGTITINNINYN-KLDHKLAAqlgigIIYQELSVIDELTVLENLYIG---RH 106
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 107 SEKQ---------EVKKELVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVS 177
Cdd:PRK09700  107 LTKKvcgvniidwREMRVRAAMMLLRVGLKVDLDEKVANLSISHKQMLEIAKTLMLDAKVIIMDEPTSSLTNKEVDYLFL 186
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 2462526932 178 LMKSLAQGGRTIICTIHQpSAKLFEMFDKLYILSQGQCIFKGVVTNL 224
Cdd:PRK09700  187 IMNQLRKEGTAIVYISHK-LAEIRRICDRYTVMKDGSSVCSGMVSDV 232
PRK10851 PRK10851
sulfate/thiosulfate ABC transporter ATP-binding protein CysA;
32-169 7.95e-11

sulfate/thiosulfate ABC transporter ATP-binding protein CysA;


Pssm-ID: 182778 [Multi-domain]  Cd Length: 353  Bit Score: 63.95  E-value: 7.95e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  32 ELIGIMGPSGAGKSTFMNILAGYrESGMKGQILVNGR------PRElrtfRKMScYIMQDDMLLPHLTVLEAmmVSANLK 105
Cdd:PRK10851   29 QMVALLGPSGSGKTTLLRIIAGL-EHQTSGHIRFHGTdvsrlhARD----RKVG-FVFQHYALFRHMTVFDN--IAFGLT 100
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2462526932 106 LSEKQE-----VKKELVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDS 169
Cdd:PRK10851  101 VLPRRErpnaaAIKAKVTQLLEMVQLAHLADRYPAQLSGGQKQRVALARALAVEPQILLLDEPFGALDA 169
livF PRK11614
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;
32-218 1.07e-10

high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;


Pssm-ID: 183231 [Multi-domain]  Cd Length: 237  Bit Score: 62.20  E-value: 1.07e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  32 ELIGIMGPSGAGKSTFMNILAGyRESGMKGQILVNGRP-RELRTFRkmscyIMQDDM-LLPH-LTVLEAMMVSANLKL-- 106
Cdd:PRK11614   32 EIVTLIGANGAGKTTLLGTLCG-DPRATSGRIVFDGKDiTDWQTAK-----IMREAVaIVPEgRRVFSRMTVEENLAMgg 105
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 107 --SEKQEVKK--ELVTEILTALglMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKSL 182
Cdd:PRK11614  106 ffAERDQFQEriKWVYELFPRL--HERRIQRAGTMSGGEQQMLAIGRALMSQPRLLLLDEPSLGLAPIIIQQIFDTIEQL 183
                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 2462526932 183 AQGGRTIIcTIHQPSAKLFEMFDKLYILSQGQCIFK 218
Cdd:PRK11614  184 REQGMTIF-LVEQNANQALKLADRGYVLENGHVVLE 218
rim_protein TIGR01257
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...
9-194 1.09e-10

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]


Pssm-ID: 130324 [Multi-domain]  Cd Length: 2272  Bit Score: 65.03  E-value: 1.09e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932    9 QKRIVASGYKT-------LLKCLSG-------KFC----RRELIGIMGPSGAGKSTFMNILAGyRESGMKGQILVNGRP- 69
Cdd:TIGR01257 1925 RQRIISGGNKTdilrlneLTKVYSGtsspavdRLCvgvrPGECFGLLGVNGAGKTTTFKMLTG-DTTVTSGDATVAGKSi 2003
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932   70 -RELRTFRKMSCYIMQDDMLLPHLTVLEAMMVSANLKLSEKQEVKKeLVTEILTALGLMSCSHTRTALLSGGQRKRLAIA 148
Cdd:TIGR01257 2004 lTNISDVHQNMGYCPQFDAIDDLLTGREHLYLYARLRGVPAEEIEK-VANWSIQSLGLSLYADRLAGTYSGGNKRKLSTA 2082
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*.
gi 2462526932  149 LELVNNPPVMFFDEPTSGLDSASCFQVVSLMKSLAQGGRTIICTIH 194
Cdd:TIGR01257 2083 IALIGCPPLVLLDEPTTGMDPQARRMLWNTIVSIIREGRAVVLTSH 2128
PRK15439 PRK15439
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
36-195 1.19e-10

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional


Pssm-ID: 185336 [Multi-domain]  Cd Length: 510  Bit Score: 63.92  E-value: 1.19e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  36 IMGPSGAGKSTFMNILAGYrESGMKGQILVNGRPRELRT---FRKMSCYIM-QDDMLLPHLTVLEAMMvsanLKLSEKQE 111
Cdd:PRK15439   42 LLGGNGAGKSTLMKIIAGI-VPPDSGTLEIGGNPCARLTpakAHQLGIYLVpQEPLLFPNLSVKENIL----FGLPKRQA 116
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 112 VKKELvTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKSLAQGGRTIIC 191
Cdd:PRK15439  117 SMQKM-KQLLAALGCQLDLDSSAGSLEVADRQIVEILRGLMRDSRILILDEPTASLTPAETERLFSRIRELLAQGVGIVF 195

                  ....
gi 2462526932 192 TIHQ 195
Cdd:PRK15439  196 ISHK 199
PRK10261 PRK10261
glutathione transporter ATP-binding protein; Provisional
24-231 1.29e-10

glutathione transporter ATP-binding protein; Provisional


Pssm-ID: 182342 [Multi-domain]  Cd Length: 623  Bit Score: 64.11  E-value: 1.29e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  24 LSGKFCRRELIGIMGPSGAGKS-TFMNILAGYRESGMK---GQILVNGRPRELRTFRKMSCYIMQD----DM-------- 87
Cdd:PRK10261   35 LSFSLQRGETLAIVGESGSGKSvTALALMRLLEQAGGLvqcDKMLLRRRSRQVIELSEQSAAQMRHvrgaDMamifqepm 114
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  88 --LLPHLTVLEAMMVSANLKLSEKQEvkkELVTEILTALGLMSCSHTRTAL------LSGGQRKRLAIALELVNNPPVMF 159
Cdd:PRK10261  115 tsLNPVFTVGEQIAESIRLHQGASRE---EAMVEAKRMLDQVRIPEAQTILsryphqLSGGMRQRVMIAMALSCRPAVLI 191
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2462526932 160 FDEPTSGLDSASCFQVVSLMKSLAQGGRTIICTIHQPSAKLFEMFDKLYILSQGQCIFKGVVTNLI-----PYLKGL 231
Cdd:PRK10261  192 ADEPTTALDVTIQAQILQLIKVLQKEMSMGVIFITHDMGVVAEIADRVLVMYQGEAVETGSVEQIFhapqhPYTRAL 268
PRK11176 PRK11176
lipid A ABC transporter ATP-binding protein/permease MsbA;
34-225 1.40e-10

lipid A ABC transporter ATP-binding protein/permease MsbA;


Pssm-ID: 183016 [Multi-domain]  Cd Length: 582  Bit Score: 63.88  E-value: 1.40e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  34 IGIMGPSGAGKSTFMNILAGYRESgMKGQILVNG---RPRELRTFRKMSCYIMQDdmllPHL---TVLEAMMVSANLKLS 107
Cdd:PRK11176  372 VALVGRSGSGKSTIANLLTRFYDI-DEGEILLDGhdlRDYTLASLRNQVALVSQN----VHLfndTIANNIAYARTEQYS 446
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 108 EKQ---EVKKELVTEILTAL--GLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKSL 182
Cdd:PRK11176  447 REQieeAARMAYAMDFINKMdnGLDTVIGENGVLLSGGQRQRIAIARALLRDSPILILDEATSALDTESERAIQAALDEL 526
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 2462526932 183 aQGGRTIICTIHQPSAklFEMFDKLYILSQGQCIFKGVVTNLI 225
Cdd:PRK11176  527 -QKNRTSLVIAHRLST--IEKADEILVVEDGEIVERGTHAELL 566
ArpD COG4618
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular ...
32-214 1.49e-10

ABC-type protease/lipase transport system, ATPase and permease components [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 443660 [Multi-domain]  Cd Length: 563  Bit Score: 64.00  E-value: 1.49e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  32 ELIGIMGPSGAGKSTFMNILAG-YRESGmkGQILVNGRprELRTFRKMSC-----YIMQDDMLLPHlTVLE--AMMvsan 103
Cdd:COG4618   359 EVLGVIGPSGSGKSTLARLLVGvWPPTA--GSVRLDGA--DLSQWDREELgrhigYLPQDVELFDG-TIAEniARF---- 429
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 104 lklsekQEVKKELVTE----------IL-------TALGLMSCShtrtalLSGGQRKRLAIALELVNNPPVMFFDEPTSG 166
Cdd:COG4618   430 ------GDADPEKVVAaaklagvhemILrlpdgydTRIGEGGAR------LSGGQRQRIGLARALYGDPRLVVLDEPNSN 497
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 2462526932 167 LDSASCFQVVSLMKSLAQGGRTIICTIHQPSAkLFEMfDKLYILSQGQ 214
Cdd:COG4618   498 LDDEGEAALAAAIRALKARGATVVVITHRPSL-LAAV-DKLLVLRDGR 543
ABCF_EF-3 cd03221
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is ...
16-194 1.69e-10

ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated release of the deacylated tRNA from the E site. The reaction requires ATP hydrolysis. EF-3 contains two ATP nucleotide binding sequence (NBS) motifs. NBSI is sufficient for the intrinsic ATPase activity. NBSII is essential for the ribosome-stimulated functions.


Pssm-ID: 213188 [Multi-domain]  Cd Length: 144  Bit Score: 59.38  E-value: 1.69e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  16 GYKTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAGyRESGMKGQILVNGRPRelrtfrkmSCYIMQddmllphltvl 95
Cdd:cd03221    11 GGKLLLKDISLTINPGDRIGLVGRNGAGKSTLLKLIAG-ELEPDEGIVTWGSTVK--------IGYFEQ----------- 70
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  96 eammvsanlklsekqevkkelvteiltalglmscshtrtalLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQV 175
Cdd:cd03221    71 -----------------------------------------LSGGEKMRLALAKLLLENPNLLLLDEPTNHLDLESIEAL 109
                         170
                  ....*....|....*....
gi 2462526932 176 VSLMKSLaQGgrTIICTIH 194
Cdd:cd03221   110 EEALKEY-PG--TVILVSH 125
PRK13543 PRK13543
heme ABC exporter ATP-binding protein CcmA;
32-168 2.46e-10

heme ABC exporter ATP-binding protein CcmA;


Pssm-ID: 184129 [Multi-domain]  Cd Length: 214  Bit Score: 60.63  E-value: 2.46e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  32 ELIGIMGPSGAGKSTFMNILAGYRESGmKGQILVNGRPRELRTFRKMSCYIMQDDMLLPHLTVLEAMMVSANLKLSEKQE 111
Cdd:PRK13543   38 EALLVQGDNGAGKTTLLRVLAGLLHVE-SGQIQIDGKTATRGDRSRFMAYLGHLPGLKADLSTLENLHFLCGLHGRRAKQ 116
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2462526932 112 VKkelvTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLD 168
Cdd:PRK13543  117 MP----GSALAIVGLAGYEDTLVRQLSAGQKKRLALARLWLSPAPLWLLDEPYANLD 169
PRK13549 PRK13549
xylose transporter ATP-binding subunit; Provisional
32-216 2.56e-10

xylose transporter ATP-binding subunit; Provisional


Pssm-ID: 184134 [Multi-domain]  Cd Length: 506  Bit Score: 63.02  E-value: 2.56e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  32 ELIGIMGPSGAGKSTFMNILAG-YRESGMKGQILVNGRPRELRTFR----KMSCYIMQDDMLLPHLTVLEAMMVSANL-- 104
Cdd:PRK13549   32 EIVSLCGENGAGKSTLMKVLSGvYPHGTYEGEIIFEGEELQASNIRdterAGIAIIHQELALVKELSVLENIFLGNEItp 111
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 105 -KLSEKQEVKKElVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKSLA 183
Cdd:PRK13549  112 gGIMDYDAMYLR-AQKLLAQLKLDINPATPVGNLGLGQQQLVEIAKALNKQARLLILDEPTASLTESETAVLLDIIRDLK 190
                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 2462526932 184 QGGRTIICTIHqpsaKLFEMF---DKLYILSQGQCI 216
Cdd:PRK13549  191 AHGIACIYISH----KLNEVKaisDTICVIRDGRHI 222
oppD PRK09473
oligopeptide transporter ATP-binding component; Provisional
32-193 3.94e-10

oligopeptide transporter ATP-binding component; Provisional


Pssm-ID: 181888 [Multi-domain]  Cd Length: 330  Bit Score: 61.66  E-value: 3.94e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  32 ELIGIMGPSGAGKS----TFMNILAGY-RESG---MKGQILVNGRPRELRTFR--KMScYIMQDDM--LLPHLTVLEAMM 99
Cdd:PRK09473   43 ETLGIVGESGSGKSqtafALMGLLAANgRIGGsatFNGREILNLPEKELNKLRaeQIS-MIFQDPMtsLNPYMRVGEQLM 121
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 100 VSANL-KLSEKQEVKKELVtEILTALGlMSCSHTRTAL----LSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQ 174
Cdd:PRK09473  122 EVLMLhKGMSKAEAFEESV-RMLDAVK-MPEARKRMKMypheFSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQ 199
                         170
                  ....*....|....*....
gi 2462526932 175 VVSLMKSLAQGGRTIICTI 193
Cdd:PRK09473  200 IMTLLNELKREFNTAIIMI 218
ABC_RNaseL_inhibitor_domain2 cd03237
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ...
21-169 4.61e-10

The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity of more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213204 [Multi-domain]  Cd Length: 246  Bit Score: 60.11  E-value: 4.61e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  21 LKCLSGKFCRRELIGIMGPSGAGKSTFMNILAGyRESGMKGQILVngrprELRTFRKMSCYIMQD-DMllphlTVLEAMM 99
Cdd:cd03237    15 LEVEGGSISESEVIGILGPNGIGKTTFIKMLAG-VLKPDEGDIEI-----ELDTVSYKPQYIKADyEG-----TVRDLLS 83
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 100 VSANLKLSEKQevkkeLVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDS 169
Cdd:cd03237    84 SITKDFYTHPY-----FKTEIAKPLQIEQILDREVPELSGGELQRVAIAACLSKDADIYLLDEPSAYLDV 148
PRK13549 PRK13549
xylose transporter ATP-binding subunit; Provisional
30-214 4.79e-10

xylose transporter ATP-binding subunit; Provisional


Pssm-ID: 184134 [Multi-domain]  Cd Length: 506  Bit Score: 62.25  E-value: 4.79e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  30 RRELIGIMGPSGAGKSTFMNILAGYRESGMKGQILVNGRPRELRTFRKMS----CYIMQD---DMLLPHLTVLEAMMVSA 102
Cdd:PRK13549  287 RGEILGIAGLVGAGRTELVQCLFGAYPGRWEGEIFIDGKPVKIRNPQQAIaqgiAMVPEDrkrDGIVPVMGVGKNITLAA 366
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 103 NLKLSEKQEVKKEL-VTEILTALGLM----SCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVS 177
Cdd:PRK13549  367 LDRFTGGSRIDDAAeLKTILESIQRLkvktASPELAIARLSGGNQQKAVLAKCLLLNPKILILDEPTRGIDVGAKYEIYK 446
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 2462526932 178 LMKSLAQGGRTIICTihqpSAKLFE---MFDKLYILSQGQ 214
Cdd:PRK13549  447 LINQLVQQGVAIIVI----SSELPEvlgLSDRVLVMHEGK 482
met_CoM_red_A2 TIGR03269
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ...
18-219 6.40e-10

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]


Pssm-ID: 132313 [Multi-domain]  Cd Length: 520  Bit Score: 61.74  E-value: 6.40e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  18 KTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAGYRE-SGMKGQILVN----------------GRP----------- 69
Cdd:TIGR03269  13 KEVLKNISFTIEEGEVLGILGRSGAGKSVLMHVLRGMDQyEPTSGRIIYHvalcekcgyverpskvGEPcpvcggtlepe 92
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  70 ---------RELRTFRKMSCYIMQDDM-LLPHLTVLEAMMVSanlkLSEKQEVKKELVTEILTALGLMSCSHTRTAL--- 136
Cdd:TIGR03269  93 evdfwnlsdKLRRRIRKRIAIMLQRTFaLYGDDTVLDNVLEA----LEEIGYEGKEAVGRAVDLIEMVQLSHRITHIard 168
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 137 LSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKSLAQG-GRTIICTIHQPSAkLFEMFDKLYILSQGQC 215
Cdd:TIGR03269 169 LSGGEKQRVVLARQLAKEPFLFLADEPTGTLDPQTAKLVHNALEEAVKAsGISMVLTSHWPEV-IEDLSDKAIWLENGEI 247

                  ....
gi 2462526932 216 IFKG 219
Cdd:TIGR03269 248 KEEG 251
xylG TIGR02633
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ...
32-216 6.94e-10

D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 131681 [Multi-domain]  Cd Length: 500  Bit Score: 61.76  E-value: 6.94e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  32 ELIGIMGPSGAGKSTFMNILAG-YRESGMKGQILVNGRPRELR----TFRKMSCYIMQDDMLLPHLTVLEAMMVSANLKL 106
Cdd:TIGR02633  28 ECVGLCGENGAGKSTLMKILSGvYPHGTWDGEIYWSGSPLKASnirdTERAGIVIIHQELTLVPELSVAENIFLGNEITL 107
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 107 SEKQEVKKELV---TEILTALGLMSCSHTRTAL-LSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKSL 182
Cdd:TIGR02633 108 PGGRMAYNAMYlraKNLLRELQLDADNVTRPVGdYGGGQQQLVEIAKALNKQARLLILDEPSSSLTEKETEILLDIIRDL 187
                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 2462526932 183 AQGGRTIICTIHqpsaKLFE---MFDKLYILSQGQCI 216
Cdd:TIGR02633 188 KAHGVACVYISH----KLNEvkaVCDTICVIRDGQHV 220
phnK PRK11701
phosphonate C-P lyase system protein PhnK; Provisional
32-168 8.21e-10

phosphonate C-P lyase system protein PhnK; Provisional


Pssm-ID: 183280 [Multi-domain]  Cd Length: 258  Bit Score: 59.55  E-value: 8.21e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  32 ELIGIMGPSGAGKSTFMNILAGyRESGMKGQILVNGRPRELRTFRKMS------------CYIMQD--DMLlphltvleA 97
Cdd:PRK11701   33 EVLGIVGESGSGKTTLLNALSA-RLAPDAGEVHYRMRDGQLRDLYALSeaerrrllrtewGFVHQHprDGL--------R 103
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  98 MMVSANLKLSEKqevkkelvteiLTALGLMSCSHTR-TAL-------------------LSGGQRKRLAIALELVNNPPV 157
Cdd:PRK11701  104 MQVSAGGNIGER-----------LMAVGARHYGDIRaTAGdwlerveidaariddlpttFSGGMQQRLQIARNLVTHPRL 172
                         170
                  ....*....|.
gi 2462526932 158 MFFDEPTSGLD 168
Cdd:PRK11701  173 VFMDEPTGGLD 183
PRK10762 PRK10762
D-ribose transporter ATP binding protein; Provisional
32-214 8.98e-10

D-ribose transporter ATP binding protein; Provisional


Pssm-ID: 236755 [Multi-domain]  Cd Length: 501  Bit Score: 61.17  E-value: 8.98e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  32 ELIGIMGPSGAGKSTFMNILAGY--RESGmkgQILVNGRPRELRT----FRKMSCYIMQD---DMLLPHLTVLEAMMVSA 102
Cdd:PRK10762  279 EILGVSGLMGAGRTELMKVLYGAlpRTSG---YVTLDGHEVVTRSpqdgLANGIVYISEDrkrDGLVLGMSVKENMSLTA 355
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 103 NLKLSE-----KQEVKKELVTEILTALGLMSCSHTRT-ALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVV 176
Cdd:PRK10762  356 LRYFSRaggslKHADEQQAVSDFIRLFNIKTPSMEQAiGLLSGGNQQKVAIARGLMTRPKVLILDEPTRGVDVGAKKEIY 435
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 2462526932 177 SLMKSLAQGGRTIICTihqpSAKLFE---MFDKLYILSQGQ 214
Cdd:PRK10762  436 QLINQFKAEGLSIILV----SSEMPEvlgMSDRILVMHEGR 472
ABC_RNaseL_inhibitor_domain1 cd03236
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ...
32-194 9.12e-10

The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI s are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLIs have an N-terminal Fe-S domain and two nucleotide binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213203 [Multi-domain]  Cd Length: 255  Bit Score: 59.69  E-value: 9.12e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  32 ELIGIMGPSGAGKSTFMNILAG--------YRESGMKGQILVNGRPRELRTFRKMscyIMQDDM----------LLPHLT 93
Cdd:cd03236    27 QVLGLVGPNGIGKSTALKILAGklkpnlgkFDDPPDWDEILDEFRGSELQNYFTK---LLEGDVkvivkpqyvdLIPKAV 103
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  94 vleAMMVSANLKLSEKQEVKKELVTeiltALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCF 173
Cdd:cd03236   104 ---KGKVGELLKKKDERGKLDELVD----QLELRHVLDRNIDQLSGGELQRVAIAAALARDADFYFFDEPSSYLDIKQRL 176
                         170       180
                  ....*....|....*....|.
gi 2462526932 174 QVVSLMKSLAQGGRTIICTIH 194
Cdd:cd03236   177 NAARLIRELAEDDNYVLVVEH 197
PRK14239 PRK14239
phosphate transporter ATP-binding protein; Provisional
16-192 9.89e-10

phosphate transporter ATP-binding protein; Provisional


Pssm-ID: 184585 [Multi-domain]  Cd Length: 252  Bit Score: 59.40  E-value: 9.89e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  16 GYKTLLKCLSGKFCRRELIGIMGPSGAGKSTF------MNILAgyRESGMKGQILVNGR----PR----ELRTFRKMscy 81
Cdd:PRK14239   16 NKKKALNSVSLDFYPNEITALIGPSGSGKSTLlrsinrMNDLN--PEVTITGSIVYNGHniysPRtdtvDLRKEIGM--- 90
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  82 IMQDDMLLPhLTVLEAMMVSANLKLSEKQEVKKELVTEILTALGLMSCSHTR---TAL-LSGGQRKRLAIALELVNNPPV 157
Cdd:PRK14239   91 VFQQPNPFP-MSIYENVVYGLRLKGIKDKQVLDEAVEKSLKGASIWDEVKDRlhdSALgLSGGQQQRVCIARVLATSPKI 169
                         170       180       190
                  ....*....|....*....|....*....|....*
gi 2462526932 158 MFFDEPTSGLDSASCFQVVSLMKSLAQGGRTIICT 192
Cdd:PRK14239  170 ILLDEPTSALDPISAGKIEETLLGLKDDYTMLLVT 204
YddA COG4178
ABC-type uncharacterized transport system, permease and ATPase components [General function ...
17-214 1.19e-09

ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only];


Pssm-ID: 443337 [Multi-domain]  Cd Length: 571  Bit Score: 60.98  E-value: 1.19e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  17 YKTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAGYRESGmKGQILvngRPRELRTfrkmscyimqddMLLPHltvlE 96
Cdd:COG4178   375 GRPLLEDLSLSLKPGERLLITGPSGSGKSTLLRAIAGLWPYG-SGRIA---RPAGARV------------LFLPQ----R 434
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  97 AMMVSANLK--LS---EKQEVKKELVTEILTALGLmscSHTRTAL---------LSGGQRKRLAIALELVNNPPVMFFDE 162
Cdd:COG4178   435 PYLPLGTLReaLLypaTAEAFSDAELREALEAVGL---GHLAERLdeeadwdqvLSLGEQQRLAFARLLLHKPDWLFLDE 511
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2462526932 163 PTSGLDSASCFQVVSLMKSLAQGGrTIICTIHQPSakLFEMFDKLYILSQGQ 214
Cdd:COG4178   512 ATSALDEENEAALYQLLREELPGT-TVISVGHRST--LAAFHDRVLELTGDG 560
40850658_otr NF000106
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
99-239 1.38e-09

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;


Pssm-ID: 411078 [Multi-domain]  Cd Length: 351  Bit Score: 60.13  E-value: 1.38e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  99 MVSANLKLSEKQevKKELVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSL 178
Cdd:NF000106  109 MIGR*LDLSRKD--ARARADELLERFSLTEAAGRAAAKYSGGMRRRLDLAASMIGRPAVLYLDEPTTGLDPRTRNEVWDE 186
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462526932 179 MKSLAQGGRTIICTIhQPSAKLFEMFDKLYILSQGQCIFKGVVTNLIPYLKGLGLHCPTYH 239
Cdd:NF000106  187 VRSMVRDGATVLLTT-QYMEEAEQLAHELTVIDRGRVIADGKVDELKTKVGGRTLQIRPAH 246
ABC_FeS_Assembly cd03217
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of ...
13-219 1.46e-09

ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of iron-sulfur clusters (Fe-S) depends on multi-protein systems. The SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and provides it to the cluster; SufE has no associated function yet.


Pssm-ID: 213184 [Multi-domain]  Cd Length: 200  Bit Score: 57.92  E-value: 1.46e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  13 VASGYKTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAG---YRESgmKGQILVNGR-----PRELRTfrKMSCYIM- 83
Cdd:cd03217     8 VSVGGKEILKGVNLTIKKGEVHALMGPNGSGKSTLAKTIMGhpkYEVT--EGEILFKGEditdlPPEERA--RLGIFLAf 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  84 QDDMLLPHLTVLEaMMVSANLKLSekqevkkelvteiltalglmscshtrtallsGGQRKRLAIALELVNNPPVMFFDEP 163
Cdd:cd03217    84 QYPPEIPGVKNAD-FLRYVNEGFS-------------------------------GGEKKRNEILQLLLLEPDLAILDEP 131
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2462526932 164 TSGLDSASCFQVVSLMKSLAQGGRTIICTIHQpsAKLFEMF--DKLYILSQGQCIFKG 219
Cdd:cd03217   132 DSGLDIDALRLVAEVINKLREEGKSVLIITHY--QRLLDYIkpDRVHVLYDGRIVKSG 187
cbiO PRK13640
energy-coupling factor transporter ATPase;
109-236 1.96e-09

energy-coupling factor transporter ATPase;


Pssm-ID: 184200 [Multi-domain]  Cd Length: 282  Bit Score: 59.04  E-value: 1.96e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 109 KQEVKKeLVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKSLA-QGGR 187
Cdd:PRK13640  117 RPEMIK-IVRDVLADVGMLDYIDSEPANLSGGQKQRVAIAGILAVEPKIIILDESTSMLDPAGKEQILKLIRKLKkKNNL 195
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2462526932 188 TIICTIHQPSAKlfEMFDKLYILSQGQCIFKGVVTNLIP---YLKGLGLHCP 236
Cdd:PRK13640  196 TVISITHDIDEA--NMADQVLVLDDGKLLAQGSPVEIFSkveMLKEIGLDIP 245
PRK13633 PRK13633
energy-coupling factor transporter ATPase;
18-236 2.15e-09

energy-coupling factor transporter ATPase;


Pssm-ID: 237453 [Multi-domain]  Cd Length: 280  Bit Score: 58.56  E-value: 2.15e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  18 KTLLKCLSGKFCRRELIGIMGPSGAGKSTF---MNILAGYREsgmkGQILVNG----RPRELRTFRKMSCYIMQ--DDML 88
Cdd:PRK13633   23 KLALDDVNLEVKKGEFLVILGRNGSGKSTIakhMNALLIPSE----GKVYVDGldtsDEENLWDIRNKAGMVFQnpDNQI 98
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  89 LPhlTVLEAMMVSANLKLSEKQEVKKELVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLD 168
Cdd:PRK13633   99 VA--TIVEEDVAFGPENLGIPPEEIRERVDESLKKVGMYEYRRHAPHLLSGGQKQRVAIAGILAMRPECIIFDEPTAMLD 176
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2462526932 169 SASCFQVVSLMKSL-AQGGRTIICTIH--QPSAKLfemfDKLYILSQGQCIFKGVVTNL---IPYLKGLGLHCP 236
Cdd:PRK13633  177 PSGRREVVNTIKELnKKYGITIILITHymEEAVEA----DRIIVMDSGKVVMEGTPKEIfkeVEMMKKIGLDVP 246
cbiO PRK13648
cobalt transporter ATP-binding subunit; Provisional
36-236 2.28e-09

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184207 [Multi-domain]  Cd Length: 269  Bit Score: 58.61  E-value: 2.28e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  36 IMGPSGAGKSTFMNILAGYrESGMKGQILVNGRP---RELRTFRKMSCYIMQDDmllphltvlEAMMVSANLKLS----- 107
Cdd:PRK13648   40 IVGHNGSGKSTIAKLMIGI-EKVKSGEIFYNNQAitdDNFEKLRKHIGIVFQNP---------DNQFVGSIVKYDvafgl 109
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 108 EKQEVK----KELVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKSLA 183
Cdd:PRK13648  110 ENHAVPydemHRRVSEALKQVDMLERADYEPNALSGGQKQRVAIAGVLALNPSVIILDEATSMLDPDARQNLLDLVRKVK 189
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2462526932 184 QGGR-TIICTIHQPSAKLFEmfDKLYILSQGQCIFKGVVTNLIPYLKGL---GLHCP 236
Cdd:PRK13648  190 SEHNiTIISITHDLSEAMEA--DHVIVMNKGTVYKEGTPTEIFDHAEELtriGLDLP 244
Rli1 COG1245
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ...
34-190 2.60e-09

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440858 [Multi-domain]  Cd Length: 592  Bit Score: 59.80  E-value: 2.60e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  34 IGIMGPSGAGKSTFMNILAGyresgmkgQILVN-GRPRE-------LRTFRKMscyIMQDdmllpHLTVLeammVSANLK 105
Cdd:COG1245   102 TGILGPNGIGKSTALKILSG--------ELKPNlGDYDEepswdevLKRFRGT---ELQD-----YFKKL----ANGEIK 161
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 106 LSEK-QEVK----------KEL---------VTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTS 165
Cdd:COG1245   162 VAHKpQYVDlipkvfkgtvRELlekvdergkLDELAEKLGLENILDRDISELSGGELQRVAIAAALLRDADFYFFDEPSS 241
                         170       180
                  ....*....|....*....|....*
gi 2462526932 166 GLDSASCFQVVSLMKSLAQGGRTII 190
Cdd:COG1245   242 YLDIYQRLNVARLIRELAEEGKYVL 266
ABCC_MRP_domain2 cd03244
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C ...
21-214 2.99e-09

ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resistance lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213211 [Multi-domain]  Cd Length: 221  Bit Score: 57.50  E-value: 2.99e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  21 LKCLSGKFCRRELIGIMGPSGAGKSTFMNILagYR-ESGMKGQILVNGRP------RELRtfRKMSCyIMQDDMLL---- 89
Cdd:cd03244    20 LKNISFSIKPGEKVGIVGRTGSGKSSLLLAL--FRlVELSSGSILIDGVDiskiglHDLR--SRISI-IPQDPVLFsgti 94
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  90 -----PHLTVLEAMMVSAnLKlsekqEVK-KELVTEILTALGLMSCShtRTALLSGGQRKRLAIALELVNNPPVMFFDEP 163
Cdd:cd03244    95 rsnldPFGEYSDEELWQA-LE-----RVGlKEFVESLPGGLDTVVEE--GGENLSVGQRQLLCLARALLRKSKILVLDEA 166
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2462526932 164 TSGLDSASCFQVVSLMKSlAQGGRTIIC------TIHQpsaklfemFDKLYILSQGQ 214
Cdd:cd03244   167 TASVDPETDALIQKTIRE-AFKDCTVLTiahrldTIID--------SDRILVLDKGR 214
dppF PRK11308
dipeptide transporter ATP-binding subunit; Provisional
36-184 3.18e-09

dipeptide transporter ATP-binding subunit; Provisional


Pssm-ID: 236898 [Multi-domain]  Cd Length: 327  Bit Score: 58.82  E-value: 3.18e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  36 IMGPSGAGKSTFMNILAGYRE--SG---MKGQILVNGRPRELRTFRKMSCYIMQDDM--LLPHLTV---LEAMMVsANLK 105
Cdd:PRK11308   46 VVGESGCGKSTLARLLTMIETptGGelyYQGQDLLKADPEAQKLLRQKIQIVFQNPYgsLNPRKKVgqiLEEPLL-INTS 124
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 106 LSEKQevKKELVTEILTALGLMSCSHTRTA-LLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKSLAQ 184
Cdd:PRK11308  125 LSAAE--RREKALAMMAKVGLRPEHYDRYPhMFSGGQRQRIAIARALMLDPDVVVADEPVSALDVSVQAQVLNLMMDLQQ 202
YadH COG0842
ABC-type multidrug transport system, permease component [Defense mechanisms];
367-580 5.02e-09

ABC-type multidrug transport system, permease component [Defense mechanisms];


Pssm-ID: 440604 [Multi-domain]  Cd Length: 200  Bit Score: 56.36  E-value: 5.02e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 367 MLFLMFAALMPTVLTFplemaVFMREHLNYWY------SLKAYYLAKTMADVPFQVVCPVVYCSIVYWMTGQPAETSRFL 440
Cdd:COG0842    11 AMSLLFTALMLTALSI-----AREREQGTLERllvtpvSRLEILLGKVLAYLLRGLLQALLVLLVALLFFGVPLRGLSLL 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 441 LFSALATATALVAQSLGLLIGAASNSLQVATFVGPVTAIPVLLFSGFFVSFKTIPTYLQWSSYLSYVRYGFEGViltiyg 520
Cdd:COG0842    86 LLLLVLLLFALAFSGLGLLISTLARSQEQASAISNLVILPLTFLSGAFFPIESLPGWLQAIAYLNPLTYFVEAL------ 159
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 521 meRGdltcleercpfrepqSILRALDVEDakLYMDFLVLGIFFLALRLLAYLVLRYRVKS 580
Cdd:COG0842   160 --RA---------------LFLGGAGLAD--VWPSLLVLLAFAVVLLALALRLFRRRLRG 200
ABCD_peroxisomal_ALDP cd03223
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding ...
36-215 5.51e-09

ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding cassette transporter (Pat) is involved in the import of very long-chain fatty acids (VLCFA) into the peroxisome. The peroxisomal membrane forms a permeability barrier for a wide variety of metabolites required for and formed during fatty acid beta-oxidation. To communicate with the cytoplasm and mitochondria, peroxisomes need dedicated proteins to transport such hydrophilic molecules across their membranes. X-linked adrenoleukodystrophy (X-ALD) is caused by mutations in the ALD gene, which encodes ALDP (adrenoleukodystrophy protein ), a peroxisomal integral membrane protein that is a member of the ATP-binding cassette (ABC) transporter protein family. The disease is characterized by a striking and unpredictable variation in phenotypic expression. Phenotypes include the rapidly progressive childhood cerebral form (CCALD), the milder adult form, adrenomyeloneuropathy (AMN), and variants without neurologic involvement (i.e. asymptomatic).


Pssm-ID: 213190 [Multi-domain]  Cd Length: 166  Bit Score: 55.62  E-value: 5.51e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  36 IMGPSGAGKSTFMNILAGYRESGmKGQIlvnGRPRELRTFrkmscYIMQddmllphltvlEAMMVSANLKlsekqevkke 115
Cdd:cd03223    32 ITGPSGTGKSSLFRALAGLWPWG-SGRI---GMPEGEDLL-----FLPQ-----------RPYLPLGTLR---------- 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 116 lvtEILtalglmscSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKSLaqgGRTIICTIHQ 195
Cdd:cd03223    82 ---EQL--------IYPWDDVLSGGEQQRLAFARLLLHKPKFVFLDEATSALDEESEDRLYQLLKEL---GITVISVGHR 147
                         170       180
                  ....*....|....*....|.
gi 2462526932 196 PS-AKLFEMfdKLYILSQGQC 215
Cdd:cd03223   148 PSlWKFHDR--VLDLDGEGGW 166
PRK10522 PRK10522
multidrug transporter membrane component/ATP-binding component; Provisional
30-214 5.92e-09

multidrug transporter membrane component/ATP-binding component; Provisional


Pssm-ID: 236707 [Multi-domain]  Cd Length: 547  Bit Score: 58.83  E-value: 5.92e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  30 RRELIGIMGPSGAGKSTFMNILAG-YRESgmKGQILVNGRP---RELRTFRKMSCYIMQDDMLLPHLTVleammvsanlk 105
Cdd:PRK10522  348 RGELLFLIGGNGSGKSTLAMLLTGlYQPQ--SGEILLDGKPvtaEQPEDYRKLFSAVFTDFHLFDQLLG----------- 414
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 106 lSEKQEVKKELVTEILTALGL---MSCSHTRTAL--LSGGQRKRLAIALELVNNPPVMFFDEPTSglDSASCFQVV---S 177
Cdd:PRK10522  415 -PEGKPANPALVEKWLERLKMahkLELEDGRISNlkLSKGQKKRLALLLALAEERDILLLDEWAA--DQDPHFRREfyqV 491
                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 2462526932 178 LMKSLAQGGRTIICTIHQPSakLFEMFDKLYILSQGQ 214
Cdd:PRK10522  492 LLPLLQEMGKTIFAISHDDH--YFIHADRLLEMRNGQ 526
ABCC_NFT1 cd03369
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type ...
21-171 5.99e-09

ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type transporter 1). NFT1 belongs to the MRP (multidrug resistance-associated protein) family of ABC transporters. Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213269 [Multi-domain]  Cd Length: 207  Bit Score: 56.27  E-value: 5.99e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  21 LKCLSGKFCRRELIGIMGPSGAGKSTFmnILAGYRES-GMKGQILVNGRP------RELRtfRKMSCyIMQDDMLLphlt 93
Cdd:cd03369    24 LKNVSFKVKAGEKIGIVGRTGAGKSTL--ILALFRFLeAEEGKIEIDGIDistiplEDLR--SSLTI-IPQDPTLF---- 94
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2462526932  94 vleAMMVSANLKLSEKQEVKkelvtEILTALGLMSCSHTrtalLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSAS 171
Cdd:cd03369    95 ---SGTIRSNLDPFDEYSDE-----EIYGALRVSEGGLN----LSQGQRQLLCLARALLKRPRVLVLDEATASIDYAT 160
PRK10762 PRK10762
D-ribose transporter ATP binding protein; Provisional
35-224 6.28e-09

D-ribose transporter ATP binding protein; Provisional


Pssm-ID: 236755 [Multi-domain]  Cd Length: 501  Bit Score: 58.48  E-value: 6.28e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  35 GIMGPSGAGKSTFMNILAG-YRESGmkGQILVNGRPRelrTFR--KMS-----CYIMQDDMLLPHLTVLEammvsaNLKL 106
Cdd:PRK10762   34 ALVGENGAGKSTMMKVLTGiYTRDA--GSILYLGKEV---TFNgpKSSqeagiGIIHQELNLIPQLTIAE------NIFL 102
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 107 SekQEVK--------KELVTE---ILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGL---DSASC 172
Cdd:PRK10762  103 G--REFVnrfgridwKKMYAEadkLLARLNLRFSSDKLVGELSIGEQQMVEIAKVLSFESKVIIMDEPTDALtdtETESL 180
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2462526932 173 FQVVSLMKslAQGgrtiiCTIHQPSAKLFEMF---DKLYILSQGQCIFKGVVTNL 224
Cdd:PRK10762  181 FRVIRELK--SQG-----RGIVYISHRLKEIFeicDDVTVFRDGQFIAEREVADL 228
PRK10261 PRK10261
glutathione transporter ATP-binding protein; Provisional
32-182 6.82e-09

glutathione transporter ATP-binding protein; Provisional


Pssm-ID: 182342 [Multi-domain]  Cd Length: 623  Bit Score: 58.71  E-value: 6.82e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  32 ELIGIMGPSGAGKSTFMNILAGYRESgMKGQILVNGR------PRELRTFRKMSCYIMQDDM--LLPHLTVLEAMMVSAN 103
Cdd:PRK10261  351 ETLSLVGESGSGKSTTGRALLRLVES-QGGEIIFNGQridtlsPGKLQALRRDIQFIFQDPYasLDPRQTVGDSIMEPLR 429
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 104 LKLSEKQEVKKELVTEILTALGLMSCSHTRTA-LLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKSL 182
Cdd:PRK10261  430 VHGLLPGKAAAARVAWLLERVGLLPEHAWRYPhEFSGGQRQRICIARALALNPKVIIADEAVSALDVSIRGQIINLLLDL 509
PvdE COG4615
ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion ...
32-162 7.10e-09

ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion transport and metabolism];


Pssm-ID: 443659 [Multi-domain]  Cd Length: 547  Bit Score: 58.27  E-value: 7.10e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  32 ELIGIMGPSGAGKSTFMNILAG-YRESGmkGQILVNGRP---RELRTFRKMSCYIMQDDMLLPHLtvleammvsanlkLS 107
Cdd:COG4615   359 ELVFIVGGNGSGKSTLAKLLTGlYRPES--GEILLDGQPvtaDNREAYRQLFSAVFSDFHLFDRL-------------LG 423
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2462526932 108 EKQEVKKELVTEILTALGLmscSH---------TRTALlSGGQRKRLAIALELVNNPPVMFFDE 162
Cdd:COG4615   424 LDGEADPARARELLERLEL---DHkvsvedgrfSTTDL-SQGQRKRLALLVALLEDRPILVFDE 483
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
30-200 8.51e-09

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 54.69  E-value: 8.51e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932   30 RRELIGIMGPSGAGKSTFMNILAGYRESGMKGQILVNGrprelrtfrkmscyimqddmllphltvleammvsanlklsek 109
Cdd:smart00382   1 PGEVILIVGPPGSGKTTLARALARELGPPGGGVIYIDG------------------------------------------ 38
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  110 qevkkELVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSAS------CFQVVSLMKSLA 183
Cdd:smart00382  39 -----EDILEEVLDQLLLIIVGGKKASGSGELRLRLALALARKLKPDVLILDEITSLLDAEQeallllLEELRLLLLLKS 113
                          170
                   ....*....|....*..
gi 2462526932  184 QGGRTIICTIHQPSAKL 200
Cdd:smart00382 114 EKNLTVILTTNDEKDLG 130
YejF COG4172
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ...
30-184 9.62e-09

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443332 [Multi-domain]  Cd Length: 533  Bit Score: 58.16  E-value: 9.62e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  30 RRELIGIMGPSGAGKS-TFMNI--LAGYRESGMKGQILVNGR------PRELRTFR--KMSCyIMQDDM--LLPHLTVle 96
Cdd:COG4172    35 AGETLALVGESGSGKSvTALSIlrLLPDPAAHPSGSILFDGQdllglsERELRRIRgnRIAM-IFQEPMtsLNPLHTI-- 111
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  97 ammvsanlklsEKQ--EV--------KKELVTEILTALGLMSCSHTRTAL------LSGGQRKRLAIALELVNNPPVMFF 160
Cdd:COG4172   112 -----------GKQiaEVlrlhrglsGAAARARALELLERVGIPDPERRLdayphqLSGGQRQRVMIAMALANEPDLLIA 180
                         170       180
                  ....*....|....*....|....*..
gi 2462526932 161 DEPTSGLD---SAscfQVVSLMKSLAQ 184
Cdd:COG4172   181 DEPTTALDvtvQA---QILDLLKDLQR 204
Rli1 COG1245
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ...
25-190 1.01e-08

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440858 [Multi-domain]  Cd Length: 592  Bit Score: 57.87  E-value: 1.01e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  25 SGKFCRRELIGIMGPSGAGKSTFMNILAGYRE--SG-MKGQILVNGRPRelrtfrkmscYIMQD-DMllphlTVLEAMMV 100
Cdd:COG1245   360 GGEIREGEVLGIVGPNGIGKTTFAKILAGVLKpdEGeVDEDLKISYKPQ----------YISPDyDG-----TVEEFLRS 424
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 101 SANLKLSEKQevkkeLVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMK 180
Cdd:COG1245   425 ANTDDFGSSY-----YKTEIIKPLGLEKLLDKNVKDLSGGELQRVAIAACLSRDADLYLLDEPSAHLDVEQRLAVAKAIR 499
                         170
                  ....*....|.
gi 2462526932 181 SLAQG-GRTII 190
Cdd:COG1245   500 RFAENrGKTAM 510
ABC_ABC_ChvD TIGR03719
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ...
34-194 1.02e-08

ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.


Pssm-ID: 274744 [Multi-domain]  Cd Length: 552  Bit Score: 58.02  E-value: 1.02e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  34 IGIMGPSGAGKSTFMNILAGyresgMKGQILVNGRPRELRTFRkmscYIMQDDMLLPHLTVLEAMM-------------- 99
Cdd:TIGR03719  34 IGVLGLNGAGKSTLLRIMAG-----VDKDFNGEARPQPGIKVG----YLPQEPQLDPTKTVRENVEegvaeikdaldrfn 104
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 100 -VSANL--------KLSEKQEvkkELvTEILTALGLMSCSHT---------------RTALLSGGQRKRLAIALELVNNP 155
Cdd:TIGR03719 105 eISAKYaepdadfdKLAAEQA---EL-QEIIDAADAWDLDSQleiamdalrcppwdaDVTKLSGGERRRVALCRLLLSKP 180
                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 2462526932 156 PVMFFDEPTSGLDSAScfqVVSLMKSLAQGGRTIICTIH 194
Cdd:TIGR03719 181 DMLLLDEPTNHLDAES---VAWLERHLQEYPGTVVAVTH 216
cbiO PRK13645
energy-coupling factor transporter ATPase;
27-219 1.09e-08

energy-coupling factor transporter ATPase;


Pssm-ID: 184204 [Multi-domain]  Cd Length: 289  Bit Score: 56.55  E-value: 1.09e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  27 KFCRRELIGIMGPSGAGKSTFMNILAGYRESgMKGQILVNG--------RPRELRTFRKMSCYIMQDDMLLPHLTVLEAM 98
Cdd:PRK13645   33 TFKKNKVTCVIGTTGSGKSTMIQLTNGLIIS-ETGQTIVGDyaipanlkKIKEVKRLRKEIGLVFQFPEYQLFQETIEKD 111
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  99 MVSANLKLSE-KQEVKKElVTEILTALGLMSCSHTRTAL-LSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVV 176
Cdd:PRK13645  112 IAFGPVNLGEnKQEAYKK-VPELLKLVQLPEDYVKRSPFeLSGGQKRRVALAGIIAMDGNTLVLDEPTGGLDPKGEEDFI 190
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 2462526932 177 SLMKSLAQG-GRTIICTIHQPSaKLFEMFDKLYILSQGQCIFKG 219
Cdd:PRK13645  191 NLFERLNKEyKKRIIMVTHNMD-QVLRIADEVIVMHEGKVISIG 233
PRK13409 PRK13409
ribosome biogenesis/translation initiation ATPase RLI;
34-185 1.12e-08

ribosome biogenesis/translation initiation ATPase RLI;


Pssm-ID: 184037 [Multi-domain]  Cd Length: 590  Bit Score: 57.90  E-value: 1.12e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  34 IGIMGPSGAGKSTFMNILAG--------YRESGMKGQILVNGRPRELRT-FRKMSC----------YImqdDmLLPHL-- 92
Cdd:PRK13409  102 TGILGPNGIGKTTAVKILSGelipnlgdYEEEPSWDEVLKRFRGTELQNyFKKLYNgeikvvhkpqYV---D-LIPKVfk 177
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  93 -TVLEAmmvsanLKLSEKQEVKKELVTEiltaLGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSAS 171
Cdd:PRK13409  178 gKVREL------LKKVDERGKLDEVVER----LGLENILDRDISELSGGELQRVAIAAALLRDADFYFFDEPTSYLDIRQ 247
                         170
                  ....*....|....
gi 2462526932 172 CFQVVSLMKSLAQG 185
Cdd:PRK13409  248 RLNVARLIRELAEG 261
PRK13540 PRK13540
cytochrome c biogenesis protein CcmA; Provisional
20-195 1.25e-08

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 184127 [Multi-domain]  Cd Length: 200  Bit Score: 55.34  E-value: 1.25e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  20 LLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAG-YRESgmKGQILVNGR--PRELRTFRKMSCYIMQDDMLLPHLTVLE 96
Cdd:PRK13540   16 LLQQISFHLPAGGLLHLKGSNGAGKTTLLKLIAGlLNPE--KGEILFERQsiKKDLCTYQKQLCFVGHRSGINPYLTLRE 93
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  97 AMMVSANLKLSEKQevkkelVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVV 176
Cdd:PRK13540   94 NCLYDIHFSPGAVG------ITELCRLFSLEHLIDYPCGLLSSGQKRQVALLRLWMSKAKLWLLDEPLVALDELSLLTII 167
                         170
                  ....*....|....*....
gi 2462526932 177 SLMKSLAQGGRTIICTIHQ 195
Cdd:PRK13540  168 TKIQEHRAKGGAVLLTSHQ 186
PRK10790 PRK10790
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;
31-169 1.92e-08

SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;


Pssm-ID: 182733 [Multi-domain]  Cd Length: 592  Bit Score: 57.04  E-value: 1.92e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  31 RELIGIMGPSGAGKSTFMNILAGYReSGMKGQILVNGRPREL---RTFRKMSCYIMQDDMLLphltvleAMMVSANLKLS 107
Cdd:PRK10790  367 RGFVALVGHTGSGKSTLASLLMGYY-PLTEGEIRLDGRPLSSlshSVLRQGVAMVQQDPVVL-------ADTFLANVTLG 438
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2462526932 108 ekQEVKKELVTEILTALGLMSCS-------HTRTA----LLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDS 169
Cdd:PRK10790  439 --RDISEEQVWQALETVQLAELArslpdglYTPLGeqgnNLSVGQKQLLALARVLVQTPQILILDEATANIDS 509
ABC_KpsT_Wzt cd03220
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC ...
10-219 2.13e-08

ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.


Pssm-ID: 213187 [Multi-domain]  Cd Length: 224  Bit Score: 54.85  E-value: 2.13e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  10 KRIVASGYKTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAG-YRESgmKGQILVNGRPR---ELRTFrkmscyimqd 85
Cdd:cd03220    27 GRKGEVGEFWALKDVSFEVPRGERIGLIGRNGAGKSTLLRLLAGiYPPD--SGTVTVRGRVSsllGLGGG---------- 94
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  86 dmLLPHLTVLE-AMMVSANLKLSEKQevKKELVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPT 164
Cdd:cd03220    95 --FNPELTGREnIYLNGRLLGLSRKE--IDEKIDEIIEFSELGDFIDLPVKTYSSGMKARLAFAIATALEPDILLIDEVL 170
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2462526932 165 SGLDSAscFQ--VVSLMKSLAQGGRTIICTIHQPSAkLFEMFDKLYILSQGQCIFKG 219
Cdd:cd03220   171 AVGDAA--FQekCQRRLRELLKQGKTVILVSHDPSS-IKRLCDRALVLEKGKIRFDG 224
PRK11147 PRK11147
ABC transporter ATPase component; Reviewed
32-168 2.50e-08

ABC transporter ATPase component; Reviewed


Pssm-ID: 236861 [Multi-domain]  Cd Length: 635  Bit Score: 56.88  E-value: 2.50e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  32 ELIGIMGPSGAGKSTFMNILAGyrESGM-KGQI-----LVNGR-----PRE-------------------LRTFRKMSCY 81
Cdd:PRK11147   30 ERVCLVGRNGAGKSTLMKILNG--EVLLdDGRIiyeqdLIVARlqqdpPRNvegtvydfvaegieeqaeyLKRYHDISHL 107
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  82 IMQD--DMLLPHLTVLEAMMVSANLKLSEKQevkkelVTEILTALGLMScsHTRTALLSGGQRKRLAIALELVNNPPVMF 159
Cdd:PRK11147  108 VETDpsEKNLNELAKLQEQLDHHNLWQLENR------INEVLAQLGLDP--DAALSSLSGGWLRKAALGRALVSNPDVLL 179

                  ....*....
gi 2462526932 160 FDEPTSGLD 168
Cdd:PRK11147  180 LDEPTNHLD 188
MK0520 COG2401
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction ...
32-196 2.53e-08

ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction only];


Pssm-ID: 441957 [Multi-domain]  Cd Length: 222  Bit Score: 54.58  E-value: 2.53e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  32 ELIGIMGPSGAGKSTFMNILAGyRESGMKGQilvngrprelrtfrkmSCYIMQDDMLLPHLTVLEAmmvsanlkLSEKQE 111
Cdd:COG2401    57 EIVLIVGASGSGKSTLLRLLAG-ALKGTPVA----------------GCVDVPDNQFGREASLIDA--------IGRKGD 111
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 112 VKkeLVTEILTALGLMSCS--HTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKSLAQ-GGRT 188
Cdd:COG2401   112 FK--DAVELLNAVGLSDAVlwLRRFKELSTGQKFRFRLALLLAERPKLLVIDEFCSHLDRQTAKRVARNLQKLARrAGIT 189

                  ....*...
gi 2462526932 189 IICTIHQP 196
Cdd:COG2401   190 LVVATHHY 197
modC PRK11144
molybdenum ABC transporter ATP-binding protein ModC;
36-168 2.93e-08

molybdenum ABC transporter ATP-binding protein ModC;


Pssm-ID: 182993 [Multi-domain]  Cd Length: 352  Bit Score: 56.04  E-value: 2.93e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  36 IMGPSGAGKSTFMNILAGYrESGMKGQILVNGR---PRELRTF-----RKMScYIMQDDMLLPHLTVleammvSANLKLS 107
Cdd:PRK11144   29 IFGRSGAGKTSLINAISGL-TRPQKGRIVLNGRvlfDAEKGIClppekRRIG-YVFQDARLFPHYKV------RGNLRYG 100
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2462526932 108 ekqeVKKELVTEILTALGLMSCSH--TRTAL-LSGGQRKRLAIALELVNNPPVMFFDEPTSGLD 168
Cdd:PRK11144  101 ----MAKSMVAQFDKIVALLGIEPllDRYPGsLSGGEKQRVAIGRALLTAPELLLMDEPLASLD 160
PRK15134 PRK15134
microcin C ABC transporter ATP-binding protein YejF; Provisional
3-184 3.96e-08

microcin C ABC transporter ATP-binding protein YejF; Provisional


Pssm-ID: 237917 [Multi-domain]  Cd Length: 529  Bit Score: 55.87  E-value: 3.96e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932   3 GFSHAFQKRIVASGyktllkcLSGKFCRRELIGIMGPSGAGKS-TFMNIL-------AGYRESGMK--GQILVNGRPREL 72
Cdd:PRK15134   14 AFRQQQTVRTVVND-------VSLQIEAGETLALVGESGSGKSvTALSILrllpsppVVYPSGDIRfhGESLLHASEQTL 86
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  73 RTFR--KMScYIMQDDMllphltvleammVSAN-LKLSEKQ--EV--------KKELVTEILTALGLMSCSHTRTAL--- 136
Cdd:PRK15134   87 RGVRgnKIA-MIFQEPM------------VSLNpLHTLEKQlyEVlslhrgmrREAARGEILNCLDRVGIRQAAKRLtdy 153
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2462526932 137 ---LSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKSLAQ 184
Cdd:PRK15134  154 phqLSGGERQRVMIAMALLTRPELLIADEPTTALDVSVQAQILQLLRELQQ 204
ycf16 CHL00131
sulfate ABC transporter protein; Validated
32-222 4.99e-08

sulfate ABC transporter protein; Validated


Pssm-ID: 214372 [Multi-domain]  Cd Length: 252  Bit Score: 54.26  E-value: 4.99e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  32 ELIGIMGPSGAGKSTFMNILAGYRE-SGMKGQILVNGR-----PRELRTfrKMSCYI-MQDDMLLPHLTVLEAMMVSANL 104
Cdd:CHL00131   34 EIHAIMGPNGSGKSTLSKVIAGHPAyKILEGDILFKGEsildlEPEERA--HLGIFLaFQYPIEIPGVSNADFLRLAYNS 111
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 105 KLSEKQEVKK------ELVTEILTALGLMSCSHTRTAL--LSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVV 176
Cdd:CHL00131  112 KRKFQGLPELdpleflEIINEKLKLVGMDPSFLSRNVNegFSGGEKKRNEILQMALLDSELAILDETDSGLDIDALKIIA 191
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 2462526932 177 SLMKSLAQGGRTIICTIHQPsaKLFEMF--DKLYILSQGQCIFKGVVT 222
Cdd:CHL00131  192 EGINKLMTSENSIILITHYQ--RLLDYIkpDYVHVMQNGKIIKTGDAE 237
ABCC_MRP_domain1 cd03250
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This ...
20-214 5.33e-08

ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This subfamily is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213217 [Multi-domain]  Cd Length: 204  Bit Score: 53.24  E-value: 5.33e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  20 LLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAGyrESG-MKGQILVNGRprelrtfrkMScYIMQddmllphltvlEAM 98
Cdd:cd03250    20 TLKDINLEVPKGELVAIVGPVGSGKSSLLSALLG--ELEkLSGSVSVPGS---------IA-YVSQ-----------EPW 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  99 MVSANLK------LSEKQEVKKELVT--------EILTAlGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPT 164
Cdd:cd03250    77 IQNGTIRenilfgKPFDEERYEKVIKacalepdlEILPD-GDLTEIGEKGINLSGGQKQRISLARAVYSDADIYLLDDPL 155
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2462526932 165 SGLDSascfQVVS-LMKSLAQG----GRTIICTIHQPSakLFEMFDKLYILSQGQ 214
Cdd:cd03250   156 SAVDA----HVGRhIFENCILGlllnNKTRILVTHQLQ--LLPHADQIVVLDNGR 204
PRK15112 PRK15112
peptide ABC transporter ATP-binding protein SapF;
31-219 6.04e-08

peptide ABC transporter ATP-binding protein SapF;


Pssm-ID: 185067 [Multi-domain]  Cd Length: 267  Bit Score: 54.03  E-value: 6.04e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  31 RELIGIMGPSGAGKSTFMNILAGYRESGmKGQILVNGRPRELRTFRKMSC---YIMQD--DMLLPHLTVLEAMMVSANLK 105
Cdd:PRK15112   39 GQTLAIIGENGSGKSTLAKMLAGMIEPT-SGELLIDDHPLHFGDYSYRSQrirMIFQDpsTSLNPRQRISQILDFPLRLN 117
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 106 LSEKQEVKKELVTEILTALGLMScSHTR--TALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKSL- 182
Cdd:PRK15112  118 TDLEPEQREKQIIETLRQVGLLP-DHASyyPHMLAPGQKQRLGLARALILRPKVIIADEALASLDMSMRSQLINLMLELq 196
                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 2462526932 183 -AQGGRTIICTIHQPSAKlfEMFDKLYILSQGQCIFKG 219
Cdd:PRK15112  197 eKQGISYIYVTQHLGMMK--HISDQVLVMHQGEVVERG 232
cbiO PRK13634
cobalt transporter ATP-binding subunit; Provisional
36-195 6.70e-08

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237454 [Multi-domain]  Cd Length: 290  Bit Score: 54.26  E-value: 6.70e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  36 IMGPSGAGKSTFMNILAGYRESgMKGQI------LVNG-RPRELRTFRKMSCYIMQddmlLPHLTVLEAMMVS------A 102
Cdd:PRK13634   38 IIGHTGSGKSTLLQHLNGLLQP-TSGTVtigervITAGkKNKKLKPLRKKVGIVFQ----FPEHQLFEETVEKdicfgpM 112
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 103 NLKLSEKQevKKELVTEILTALGLMSCSHTRTAL-LSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKS 181
Cdd:PRK13634  113 NFGVSEED--AKQKAREMIELVGLPEELLARSPFeLSGGQMRRVAIAGVLAMEPEVLVLDEPTAGLDPKGRKEMMEMFYK 190
                         170
                  ....*....|....*
gi 2462526932 182 LAQ-GGRTIICTIHQ 195
Cdd:PRK13634  191 LHKeKGLTTVLVTHS 205
PRK13409 PRK13409
ribosome biogenesis/translation initiation ATPase RLI;
30-168 1.15e-07

ribosome biogenesis/translation initiation ATPase RLI;


Pssm-ID: 184037 [Multi-domain]  Cd Length: 590  Bit Score: 54.81  E-value: 1.15e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  30 RRELIGIMGPSGAGKSTFMNILAGYRE--SG-MKGQILVNGRPRelrtfrkmscYIMQDdmllPHLTVlEAMMVSANLKL 106
Cdd:PRK13409  364 EGEVIGIVGPNGIGKTTFAKLLAGVLKpdEGeVDPELKISYKPQ----------YIKPD----YDGTV-EDLLRSITDDL 428
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462526932 107 SEKQevkkeLVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLD 168
Cdd:PRK13409  429 GSSY-----YKSEIIKPLQLERLLDKNVKDLSGGELQRVAIAACLSRDADLYLLDEPSAHLD 485
nikD PRK10418
nickel transporter ATP-binding protein NikD; Provisional
30-184 1.19e-07

nickel transporter ATP-binding protein NikD; Provisional


Pssm-ID: 236688 [Multi-domain]  Cd Length: 254  Bit Score: 53.16  E-value: 1.19e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  30 RRELIGIMGPSGAGKS----TFMNIL-AGYRESGmkGQILVNGRPRELRTFR-KMSCYIMQD--DMLLPHLTVleAMMVS 101
Cdd:PRK10418   28 RGRVLALVGGSGSGKSltcaAALGILpAGVRQTA--GRVLLDGKPVAPCALRgRKIATIMQNprSAFNPLHTM--HTHAR 103
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 102 ANLKLSEKQEVKKELVtEILTALGLmscSHTRTAL------LSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQV 175
Cdd:PRK10418  104 ETCLALGKPADDATLT-AALEAVGL---ENAARVLklypfeMSGGMLQRMMIALALLCEAPFIIADEPTTDLDVVAQARI 179

                  ....*....
gi 2462526932 176 VSLMKSLAQ 184
Cdd:PRK10418  180 LDLLESIVQ 188
ABC_Class2 cd03227
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems ...
137-210 1.69e-07

ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems involved in cellular processes other than transport. These families are characterized by the fact that the ABC subunit is made up of duplicated, fused ABC modules (ABC2). No known transmembrane proteins or domains are associated with these proteins.


Pssm-ID: 213194 [Multi-domain]  Cd Length: 162  Bit Score: 51.21  E-value: 1.69e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2462526932 137 LSGGQRKRLAIALEL----VNNPPVMFFDEPTSGLDSASCFQVVSLMKSLAQGGRTIICTIHQPsaKLFEMFDKLYIL 210
Cdd:cd03227    78 LSGGEKELSALALILalasLKPRPLYILDEIDRGLDPRDGQALAEAILEHLVKGAQVIVITHLP--ELAELADKLIHI 153
ATM1 COG5265
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components ...
137-190 1.88e-07

ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444078 [Multi-domain]  Cd Length: 605  Bit Score: 54.06  E-value: 1.88e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2462526932 137 LSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKSLAQGGRTII 190
Cdd:COG5265   495 LSGGEKQRVAIARTLLKNPPILIFDEATSALDSRTERAIQAALREVARGRTTLV 548
PRK10253 PRK10253
iron-enterobactin ABC transporter ATP-binding protein;
16-194 3.48e-07

iron-enterobactin ABC transporter ATP-binding protein;


Pssm-ID: 182336 [Multi-domain]  Cd Length: 265  Bit Score: 51.91  E-value: 3.48e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  16 GYKTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAGYReSGMKGQILVNGRPRELRTFRKMSCYI--MQDDMLLPHLT 93
Cdd:PRK10253   18 GKYTVAENLTVEIPDGHFTAIIGPNGCGKSTLLRTLSRLM-TPAHGHVWLDGEHIQHYASKEVARRIglLAQNATTPGDI 96
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  94 VLEAMMVSANLK----LSEKQEVKKELVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDS 169
Cdd:PRK10253   97 TVQELVARGRYPhqplFTRWRKEDEEAVTKAMQATGITHLADQSVDTLSGGQRQRAWIAMVLAQETAIMLLDEPTTWLDI 176
                         170       180
                  ....*....|....*....|....*.
gi 2462526932 170 ASCFQVVSLMKSL-AQGGRTIICTIH 194
Cdd:PRK10253  177 SHQIDLLELLSELnREKGYTLAAVLH 202
TagH COG1134
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ...
32-219 5.03e-07

ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440749 [Multi-domain]  Cd Length: 245  Bit Score: 51.24  E-value: 5.03e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  32 ELIGIMGPSGAGKSTFMNILAG-YRESgmKGQILVNGR---PRELRTfrkmscyIMQddmllPHLTVLE-AMMVSANLKL 106
Cdd:COG1134    53 ESVGIIGRNGAGKSTLLKLIAGiLEPT--SGRVEVNGRvsaLLELGA-------GFH-----PELTGREnIYLNGRLLGL 118
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 107 SeKQEVkKELVTEIL--TALG--LmscsHT--RTalLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSAscFQ--VVSL 178
Cdd:COG1134   119 S-RKEI-DEKFDEIVefAELGdfI----DQpvKT--YSSGMRARLAFAVATAVDPDILLVDEVLAVGDAA--FQkkCLAR 188
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 2462526932 179 MKSLAQGGRTIICTIHQPSAkLFEMFDKLYILSQGQCIFKG 219
Cdd:COG1134   189 IRELRESGRTVIFVSHSMGA-VRRLCDRAIWLEKGRLVMDG 228
cbiO PRK13650
energy-coupling factor transporter ATPase;
32-214 5.19e-07

energy-coupling factor transporter ATPase;


Pssm-ID: 184209 [Multi-domain]  Cd Length: 279  Bit Score: 51.66  E-value: 5.19e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  32 ELIGIMGPSGAGKSTFMNILAGYRESGmKGQILVNGRPR------ELRtfRKMSCYIMQDDMLLPHLTVLEAMMVSANLK 105
Cdd:PRK13650   34 EWLSIIGHNGSGKSTTVRLIDGLLEAE-SGQIIIDGDLLteenvwDIR--HKIGMVFQNPDNQFVGATVEDDVAFGLENK 110
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 106 LSEKQEVKkELVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKSLAQG 185
Cdd:PRK13650  111 GIPHEEMK-ERVNEALELVGMQDFKEREPARLSGGQKQRVAIAGAVAMRPKIIILDEATSMLDPEGRLELIKTIKGIRDD 189
                         170       180       190
                  ....*....|....*....|....*....|..
gi 2462526932 186 -GRTIICTIHQpsakLFE--MFDKLYILSQGQ 214
Cdd:PRK13650  190 yQMTVISITHD----LDEvaLSDRVLVMKNGQ 217
PRK14243 PRK14243
phosphate transporter ATP-binding protein; Provisional
137-203 5.89e-07

phosphate transporter ATP-binding protein; Provisional


Pssm-ID: 184588 [Multi-domain]  Cd Length: 264  Bit Score: 51.32  E-value: 5.89e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2462526932 137 LSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKSLAQgGRTIICTIH--QPSAKLFEM 203
Cdd:PRK14243  152 LSGGQQQRLCIARAIAVQPEVILMDEPCSALDPISTLRIEELMHELKE-QYTIIIVTHnmQQAARVSDM 219
znuC PRK09544
high-affinity zinc transporter ATPase; Reviewed
13-168 6.07e-07

high-affinity zinc transporter ATPase; Reviewed


Pssm-ID: 181939 [Multi-domain]  Cd Length: 251  Bit Score: 50.88  E-value: 6.07e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  13 VASGYKTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAGYRESGmKGQILvngRPRELRTfrkmsCYIMQD---DMLL 89
Cdd:PRK09544   12 VSFGQRRVLSDVSLELKPGKILTLLGPNGAGKSTLVRVVLGLVAPD-EGVIK---RNGKLRI-----GYVPQKlylDTTL 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  90 PhLTVLEAMMVSANlklsekqeVKKElvtEILTALGLMSCSHTRTA---LLSGGQRKRLAIALELVNNPPVMFFDEPTSG 166
Cdd:PRK09544   83 P-LTVNRFLRLRPG--------TKKE---DILPALKRVQAGHLIDApmqKLSGGETQRVLLARALLNRPQLLVLDEPTQG 150

                  ..
gi 2462526932 167 LD 168
Cdd:PRK09544  151 VD 152
cbiO PRK13635
energy-coupling factor ABC transporter ATP-binding protein;
32-194 1.69e-06

energy-coupling factor ABC transporter ATP-binding protein;


Pssm-ID: 184195 [Multi-domain]  Cd Length: 279  Bit Score: 50.01  E-value: 1.69e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  32 ELIGIMGPSGAGKSTFMNILAG--YRESGMkgqILVNGRPRELRT---FRKMSCYIMQD-DMLLPHLTV-------LEam 98
Cdd:PRK13635   34 EWVAIVGHNGSGKSTLAKLLNGllLPEAGT---ITVGGMVLSEETvwdVRRQVGMVFQNpDNQFVGATVqddvafgLE-- 108
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  99 mvsaNLKLSEKQEVKKelVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSL 178
Cdd:PRK13635  109 ----NIGVPREEMVER--VDQALRQVGMEDFLNREPHRLSGGQKQRVAIAGVLALQPDIIILDEATSMLDPRGRREVLET 182
                         170
                  ....*....|....*..
gi 2462526932 179 MKSL-AQGGRTIICTIH 194
Cdd:PRK13635  183 VRQLkEQKGITVLSITH 199
PRK10789 PRK10789
SmdA family multidrug ABC transporter permease/ATP-binding protein;
32-219 2.29e-06

SmdA family multidrug ABC transporter permease/ATP-binding protein;


Pssm-ID: 182732 [Multi-domain]  Cd Length: 569  Bit Score: 50.48  E-value: 2.29e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  32 ELIGIMGPSGAGKSTFMNILAGYRESGmKGQILVNGRPrelrtfrkmsCYIMQDDMLLPHLTVLEAM------MVSANLK 105
Cdd:PRK10789  342 QMLGICGPTGSGKSTLLSLIQRHFDVS-EGDIRFHDIP----------LTKLQLDSWRSRLAVVSQTpflfsdTVANNIA 410
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 106 LSEKQEVKKEL--------VTEILTAL--GLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQV 175
Cdd:PRK10789  411 LGRPDATQQEIehvarlasVHDDILRLpqGYDTEVGERGVMLSGGQKQRISIARALLLNAEILILDDALSAVDGRTEHQI 490
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 2462526932 176 vslMKSLAQGG--RTIICTIHQPSAkLFEMfDKLYILSQGQCIFKG 219
Cdd:PRK10789  491 ---LHNLRQWGegRTVIISAHRLSA-LTEA-SEILVMQHGHIAQRG 531
ABC_RNaseL_inhibitor cd03222
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a ...
26-187 2.61e-06

ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins, and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains, which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213189 [Multi-domain]  Cd Length: 177  Bit Score: 47.95  E-value: 2.61e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  26 GKFCRRELIGIMGPSGAGKSTFMNILAGYREsgmkgqilvngrPRElrtfrkmscyimqDDMLLPHLTVLeammvsanlk 105
Cdd:cd03222    20 GVVKEGEVIGIVGPNGTGKTTAVKILAGQLI------------PNG-------------DNDEWDGITPV---------- 64
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 106 lsekqeVKKELVTeiltalglmscshtrtalLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKSLAQG 185
Cdd:cd03222    65 ------YKPQYID------------------LSGGELQRVAIAAALLRNATFYLFDEPSAYLDIEQRLNAARAIRRLSEE 120

                  ..
gi 2462526932 186 GR 187
Cdd:cd03222   121 GK 122
cbiO PRK13642
energy-coupling factor transporter ATPase;
21-182 3.10e-06

energy-coupling factor transporter ATPase;


Pssm-ID: 184202 [Multi-domain]  Cd Length: 277  Bit Score: 48.94  E-value: 3.10e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  21 LKCLSGKFCRRELIGIMGPSGAGKSTFMNILAGYRESgMKGQILVNGRPRELRTF----RKMSCYIMQDDMLLPHLTVLE 96
Cdd:PRK13642   23 LNGVSFSITKGEWVSIIGQNGSGKSTTARLIDGLFEE-FEGKVKIDGELLTAENVwnlrRKIGMVFQNPDNQFVGATVED 101
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  97 AMMVSANLKLSEKQEVKKElVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVV 176
Cdd:PRK13642  102 DVAFGMENQGIPREEMIKR-VDEALLAVNMLDFKTREPARLSGGQKQRVAVAGIIALRPEIIILDESTSMLDPTGRQEIM 180

                  ....*.
gi 2462526932 177 SLMKSL 182
Cdd:PRK13642  181 RVIHEI 186
ABC_ABC_ChvD TIGR03719
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ...
16-168 3.92e-06

ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.


Pssm-ID: 274744 [Multi-domain]  Cd Length: 552  Bit Score: 49.55  E-value: 3.92e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  16 GYKTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAGyRESGMKGQIlvngrprELRTFRKMSCYIMQDDMLLPHLTVL 95
Cdd:TIGR03719 333 GDKLLIDDLSFKLPPGGIVGVIGPNGAGKSTLFRMITG-QEQPDSGTI-------EIGETVKLAYVDQSRDALDPNKTVW 404
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  96 EA-------MMV------------SANLKLSEKQEvkkelvteiltalglmscshtRTALLSGGQRKRLAIALELVNNPP 156
Cdd:TIGR03719 405 EEisggldiIKLgkreipsrayvgRFNFKGSDQQK---------------------KVGQLSGGERNRVHLAKTLKSGGN 463
                         170
                  ....*....|..
gi 2462526932 157 VMFFDEPTSGLD 168
Cdd:TIGR03719 464 VLLLDEPTNDLD 475
PRK10982 PRK10982
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
131-214 4.39e-06

galactose/methyl galaxtoside transporter ATP-binding protein; Provisional


Pssm-ID: 182880 [Multi-domain]  Cd Length: 491  Bit Score: 49.34  E-value: 4.39e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 131 HTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKSLAQGGRTIIcTIHQPSAKLFEMFDKLYIL 210
Cdd:PRK10982  386 RTQIGSLSGGNQQKVIIGRWLLTQPEILMLDEPTRGIDVGAKFEIYQLIAELAKKDKGII-IISSEMPELLGITDRILVM 464

                  ....
gi 2462526932 211 SQGQ 214
Cdd:PRK10982  465 SNGL 468
dppD PRK11022
dipeptide transporter ATP-binding subunit; Provisional
32-231 5.69e-06

dipeptide transporter ATP-binding subunit; Provisional


Pssm-ID: 182906 [Multi-domain]  Cd Length: 326  Bit Score: 48.58  E-value: 5.69e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  32 ELIGIMGPSGAGKS----TFMNiLAGYRESGMKGQILVNGR------PRELRTFRKMS-CYIMQDDM--LLPHLTVLEAM 98
Cdd:PRK11022   34 EVVGIVGESGSGKSvsslAIMG-LIDYPGRVMAEKLEFNGQdlqrisEKERRNLVGAEvAMIFQDPMtsLNPCYTVGFQI 112
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  99 MVSANLKLSEKQEVKKELVTEILTALGL---MSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQV 175
Cdd:PRK11022  113 MEAIKVHQGGNKKTRRQRAIDLLNQVGIpdpASRLDVYPHQLSGGMSQRVMIAMAIACRPKLLIADEPTTALDVTIQAQI 192
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462526932 176 VSLMKSLAQGGRTIICTIHQPSAKLFEMFDKLYILSQGQCIFKGVVTNLI-----PYLKGL 231
Cdd:PRK11022  193 IELLLELQQKENMALVLITHDLALVAEAAHKIIVMYAGQVVETGKAHDIFraprhPYTQAL 253
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
30-168 7.24e-06

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 48.97  E-value: 7.24e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  30 RRELIGIMGPSGAGKSTFMNILAGYRESGmKGQILVNGRP---RELRTFRK---MScyimQDDMLLPHLTVLEAMMVSAN 103
Cdd:NF033858  291 RGEIFGFLGSNGCGKSTTMKMLTGLLPAS-EGEAWLFGQPvdaGDIATRRRvgyMS----QAFSLYGELTVRQNLELHAR 365
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2462526932 104 L-KLSEKQevKKELVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLD 168
Cdd:NF033858  366 LfHLPAAE--IAARVAEMLERFDLADVADALPDSLPLGIRQRLSLAVAVIHKPELLILDEPTSGVD 429
PRK15439 PRK15439
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
32-214 8.25e-06

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional


Pssm-ID: 185336 [Multi-domain]  Cd Length: 510  Bit Score: 48.51  E-value: 8.25e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  32 ELIGIMGPSGAGKSTFMNILAGYRESgMKGQILVNGRprelrTFRKMSCYIMQDDML--LP-----HLTVLEAMM---VS 101
Cdd:PRK15439  290 EILGLAGVVGAGRTELAETLYGLRPA-RGGRIMLNGK-----EINALSTAQRLARGLvyLPedrqsSGLYLDAPLawnVC 363
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 102 A------NLKLSEKQEvkKELVTEILTALGLmSCSHTRTAL--LSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCF 173
Cdd:PRK15439  364 AlthnrrGFWIKPARE--NAVLERYRRALNI-KFNHAEQAArtLSGGNQQKVLIAKCLEASPQLLIVDEPTRGVDVSARN 440
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 2462526932 174 QVVSLMKSLAQGGRTIICTihqpSAKLFE---MFDKLYILSQGQ 214
Cdd:PRK15439  441 DIYQLIRSIAAQNVAVLFI----SSDLEEieqMADRVLVMHQGE 480
ABC_UvrA cd03238
ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in ...
21-197 1.55e-05

ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.


Pssm-ID: 213205 [Multi-domain]  Cd Length: 176  Bit Score: 45.78  E-value: 1.55e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  21 LKCLSGKFCRRELIGIMGPSGAGKSTFmnILAGYRESGMKgqILVNGRPRelrtfrkmscyimqddmllphltvleammV 100
Cdd:cd03238    11 LQNLDVSIPLNVLVVVTGVSGSGKSTL--VNEGLYASGKA--RLISFLPK-----------------------------F 57
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 101 SANLKLSEKQevkkeLVTEILTALGLMSCSHtRTALLSGGQRKRLAIALEL-VNNPPVMF-FDEPTSGLDSASCFQVVSL 178
Cdd:cd03238    58 SRNKLIFIDQ-----LQFLIDVGLGYLTLGQ-KLSTLSGGELQRVKLASELfSEPPGTLFiLDEPSTGLHQQDINQLLEV 131
                         170
                  ....*....|....*....
gi 2462526932 179 MKSLAQGGRTIICTIHQPS 197
Cdd:cd03238   132 IKGLIDLGNTVILIEHNLD 150
PRK11819 PRK11819
putative ABC transporter ATP-binding protein; Reviewed
34-171 1.87e-05

putative ABC transporter ATP-binding protein; Reviewed


Pssm-ID: 236992 [Multi-domain]  Cd Length: 556  Bit Score: 47.42  E-value: 1.87e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  34 IGIMGPSGAGKSTFMNILAGY-RESgmkgqilvNGrprELRTFRKMSC-YIMQDDMLLPHLTVLEAMM------------ 99
Cdd:PRK11819   36 IGVLGLNGAGKSTLLRIMAGVdKEF--------EG---EARPAPGIKVgYLPQEPQLDPEKTVRENVEegvaevkaaldr 104
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 100 ---VSANL--------KLSEKQEvkkELvTEILTALGL-------------MSC--SHTRTALLSGGQRKRLAIALELVN 153
Cdd:PRK11819  105 fneIYAAYaepdadfdALAAEQG---EL-QEIIDAADAwdldsqleiamdaLRCppWDAKVTKLSGGERRRVALCRLLLE 180
                         170
                  ....*....|....*...
gi 2462526932 154 NPPVMFFDEPTSGLDSAS 171
Cdd:PRK11819  181 KPDMLLLDEPTNHLDAES 198
GguA NF040905
sugar ABC transporter ATP-binding protein;
30-216 2.60e-05

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 47.09  E-value: 2.60e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  30 RRELIGIMGPSGAGKSTFMNILAGYRESG-MKGQILVNGRPRELRTFR----KMSCYIMQDDMLLPHLTVLEammvsaNL 104
Cdd:NF040905   26 EGEIHALCGENGAGKSTLMKVLSGVYPHGsYEGEILFDGEVCRFKDIRdseaLGIVIIHQELALIPYLSIAE------NI 99
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 105 KLSEKQ---------EVKKElVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGL---DSAsc 172
Cdd:NF040905  100 FLGNERakrgvidwnETNRR-ARELLAKVGLDESPDTLVTDIGVGKQQLVEIAKALSKDVKLLILDEPTAALneeDSA-- 176
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 2462526932 173 fQVVSLMKSL-AQGGRTIIctIhqpSAKLFEMF---DKLYILSQGQCI 216
Cdd:NF040905  177 -ALLDLLLELkAQGITSII--I---SHKLNEIRrvaDSITVLRDGRTI 218
PTZ00265 PTZ00265
multidrug resistance protein (mdr1); Provisional
96-197 4.55e-05

multidrug resistance protein (mdr1); Provisional


Pssm-ID: 240339 [Multi-domain]  Cd Length: 1466  Bit Score: 46.56  E-value: 4.55e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932   96 EAMMVSANLKLSEKQEV----KKELVTEILTAL--GLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDS 169
Cdd:PTZ00265   533 ELIEMRKNYQTIKDSEVvdvsKKVLIHDFVSALpdKYETLVGSNASKLSGGQKQRISIARAIIRNPKILILDEATSSLDN 612
                           90       100
                   ....*....|....*....|....*....
gi 2462526932  170 ASCFQVVSLMKSL-AQGGRTIICTIHQPS 197
Cdd:PTZ00265   613 KSEYLVQKTINNLkGNENRITIIIAHRLS 641
GguA NF040905
sugar ABC transporter ATP-binding protein;
30-214 6.57e-05

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 45.55  E-value: 6.57e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  30 RR-ELIGIMGPSGAGKSTF-MNILA---GYRESGmkgQILVNGRPRELRTF--------------RKMSCYIMQDDML-- 88
Cdd:NF040905  284 RRgEIVGIAGLMGAGRTELaMSVFGrsyGRNISG---TVFKDGKEVDVSTVsdaidaglayvtedRKGYGLNLIDDIKrn 360
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  89 --LPHLTvleamMVSANLKLSEKQEVKkeLVTEILTALGLMSCS-HTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTS 165
Cdd:NF040905  361 itLANLG-----KVSRRGVIDENEEIK--VAEEYRKKMNIKTPSvFQKVGNLSGGNQQKVVLSKWLFTDPDVLILDEPTR 433
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2462526932 166 GLDSASCFQVVSLMKSLAQGGRTIIcTIhqpSAKLFE---MFDKLYILSQGQ 214
Cdd:NF040905  434 GIDVGAKYEIYTIINELAAEGKGVI-VI---SSELPEllgMCDRIYVMNEGR 481
PTZ00265 PTZ00265
multidrug resistance protein (mdr1); Provisional
137-171 8.85e-05

multidrug resistance protein (mdr1); Provisional


Pssm-ID: 240339 [Multi-domain]  Cd Length: 1466  Bit Score: 45.79  E-value: 8.85e-05
                           10        20        30
                   ....*....|....*....|....*....|....*
gi 2462526932  137 LSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSAS 171
Cdd:PTZ00265  1359 LSGGQKQRIAIARALLREPKILLLDEATSSLDSNS 1393
ABCC_SUR1_N cd03290
ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The ...
137-195 1.61e-04

ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The sulfonylurea receptor SUR is an ATP transporter of the ABCC/MRP family with tandem ATPase binding domains. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.


Pssm-ID: 213257 [Multi-domain]  Cd Length: 218  Bit Score: 43.47  E-value: 1.61e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462526932 137 LSGGQRKRLAIALELVNNPPVMFFDEPTSGLD---SASCFQvVSLMKSLAQGGRTIICTIHQ 195
Cdd:cd03290   141 LSGGQRQRICVARALYQNTNIVFLDDPFSALDihlSDHLMQ-EGILKFLQDDKRTLVLVTHK 201
PRK15093 PRK15093
peptide ABC transporter ATP-binding protein SapD;
137-241 1.80e-04

peptide ABC transporter ATP-binding protein SapD;


Pssm-ID: 185049 [Multi-domain]  Cd Length: 330  Bit Score: 44.02  E-value: 1.80e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 137 LSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKSLAQGGRTIICTIHQPSAKLFEMFDKLYILSQGQCI 216
Cdd:PRK15093  159 LTEGECQKVMIAIALANQPRLLIADEPTNAMEPTTQAQIFRLLTRLNQNNNTTILLISHDLQMLSQWADKINVLYCGQTV 238
                          90       100       110
                  ....*....|....*....|....*....|
gi 2462526932 217 FKGVVTNLI-----PYLKGLGLHCPTYHNP 241
Cdd:PRK15093  239 ETAPSKELVttphhPYTQALIRAIPDFGSA 268
ABC2_membrane_7 pfam19055
ABC-2 type transporter;
194-251 1.93e-04

ABC-2 type transporter;


Pssm-ID: 465963 [Multi-domain]  Cd Length: 409  Bit Score: 44.13  E-value: 1.93e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2462526932 194 HQPSAKLFEMFDKLYILSQGQCI-FKGVVTNLIPYLKGLGLHCPTYHNPADFIIEVASG 251
Cdd:pfam19055   1 HQPSYTLFKMFDDLILLAKGGLTvYHGPVKKVEEYFAGLGINVPERVNPPDHFIDILEG 59
ABC_UvrA_I cd03270
ATP-binding cassette domain I of the excision repair protein UvrA; Nucleotide excision repair ...
21-196 2.06e-04

ATP-binding cassette domain I of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.


Pssm-ID: 213237 [Multi-domain]  Cd Length: 226  Bit Score: 43.02  E-value: 2.06e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  21 LKCLSGKFCRRELIGIMGPSGAGKST--FMNILAgyresgmkgqilvNGRPRELRTFrkmSCYIMQ--DDMLLPHLTVLE 96
Cdd:cd03270    11 LKNVDVDIPRNKLVVITGVSGSGKSSlaFDTIYA-------------EGQRRYVESL---SAYARQflGQMDKPDVDSIE 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  97 AMmvSANLKLSEK---QEVKKEL--VTEI-------------------LTALGLMSCSHTRTA-LLSGG--QRKRLA--I 147
Cdd:cd03270    75 GL--SPAIAIDQKttsRNPRSTVgtVTEIydylrllfarvgirerlgfLVDVGLGYLTLSRSApTLSGGeaQRIRLAtqI 152
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 2462526932 148 ALELVNnppVMF-FDEPTSGLDSASCFQVVSLMKSLAQGGRTIICTIHQP 196
Cdd:cd03270   153 GSGLTG---VLYvLDEPSIGLHPRDNDRLIETLKRLRDLGNTVLVVEHDE 199
PLN03232 PLN03232
ABC transporter C family member; Provisional
133-213 3.20e-04

ABC transporter C family member; Provisional


Pssm-ID: 215640 [Multi-domain]  Cd Length: 1495  Bit Score: 43.81  E-value: 3.20e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  133 RTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVV-SLMKSLAQGGRTIICT--IHqpsakLFEMFDKLYI 209
Cdd:PLN03232   737 RGVNISGGQKQRVSMARAVYSNSDIYIFDDPLSALDAHVAHQVFdSCMKDELKGKTRVLVTnqLH-----FLPLMDRIIL 811

                   ....
gi 2462526932  210 LSQG 213
Cdd:PLN03232   812 VSEG 815
PRK00635 PRK00635
excinuclease ABC subunit A; Provisional
137-194 3.81e-04

excinuclease ABC subunit A; Provisional


Pssm-ID: 234806 [Multi-domain]  Cd Length: 1809  Bit Score: 43.66  E-value: 3.81e-04
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462526932  137 LSGGQRKRLAIALELVN---NPPVMFFDEPTSGLDSASCFQVVSLMKSLAQGGRTIICTIH 194
Cdd:PRK00635   810 LSGGEIQRLKLAYELLApskKPTLYVLDEPTTGLHTHDIKALIYVLQSLTHQGHTVVIIEH 870
tagH PRK13545
teichoic acids export protein ATP-binding subunit; Provisional
32-197 4.11e-04

teichoic acids export protein ATP-binding subunit; Provisional


Pssm-ID: 184130 [Multi-domain]  Cd Length: 549  Bit Score: 43.34  E-value: 4.11e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  32 ELIGIMGPSGAGKSTFMNILAGYRESGmKGQILVNGRprelrtfrkmSCYIMQDDMLLPHLTVLEAMMVSAnLKLSEKQE 111
Cdd:PRK13545   51 EIVGIIGLNGSGKSTLSNLIAGVTMPN-KGTVDIKGS----------AALIAISSGLNGQLTGIENIELKG-LMMGLTKE 118
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 112 VKKELVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKSLAQGGRTIIC 191
Cdd:PRK13545  119 KIKEIIPEIIEFADIGKFIYQPVKTYSSGMKSRLGFAISVHINPDILVIDEALSVGDQTFTKKCLDKMNEFKEQGKTIFF 198

                  ....*.
gi 2462526932 192 TIHQPS 197
Cdd:PRK13545  199 ISHSLS 204
ABC_Rad50 cd03240
ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ...
137-208 7.32e-04

ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ATP-binding cassette of ABC transporters, but are not associated with membrane-spanning domains. The conserved ATP-binding motifs common to Rad50 and the ABC transporter family include the Walker A and Walker B motifs, the Q loop, a histidine residue in the switch region, a D-loop, and a conserved LSGG sequence. This conserved sequence, LSGG, is the most specific and characteristic motif of this family and is thus known as the ABC signature sequence.


Pssm-ID: 213207 [Multi-domain]  Cd Length: 204  Bit Score: 41.05  E-value: 7.32e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 137 LSGGQRK------RLAIALELVNNPPVMFFDEPTSGLDSASC-FQVVSLMKS-LAQGGRTIICTIHQPsaKLFEMFDKLY 208
Cdd:cd03240   116 CSGGEKVlasliiRLALAETFGSNCGILALDEPTTNLDEENIeESLAEIIEErKSQKNFQLIVITHDE--ELVDAADHIY 193
AAA_21 pfam13304
AAA domain, putative AbiEii toxin, Type IV TA system; Several members are annotated as being ...
136-197 8.64e-04

AAA domain, putative AbiEii toxin, Type IV TA system; Several members are annotated as being of the abortive phage resistance system, in which case the family would be acting as the toxin for a type IV toxin-antitoxin resistance system.


Pssm-ID: 433102 [Multi-domain]  Cd Length: 303  Bit Score: 41.61  E-value: 8.64e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2462526932 136 LLSGGQRK---RLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKSLAQGGRTIICTIHQPS 197
Cdd:pfam13304 236 ELSDGTKRllaLLAALLSALPKGGLLLIDEPESGLHPKLLRRLLELLKELSRNGAQLILTTHSPL 300
PRK10938 PRK10938
putative molybdenum transport ATP-binding protein ModF; Provisional
111-190 2.22e-03

putative molybdenum transport ATP-binding protein ModF; Provisional


Pssm-ID: 182852 [Multi-domain]  Cd Length: 490  Bit Score: 40.77  E-value: 2.22e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 111 EVKKELVTEILTA-LGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKSLAQGGRTI 189
Cdd:PRK10938  109 EVKDPARCEQLAQqFGITALLDRRFKYLSTGETRKTLLCQALMSEPDLLILDEPFDGLDVASRQQLAELLASLHQSGITL 188

                  .
gi 2462526932 190 I 190
Cdd:PRK10938  189 V 189
uvra TIGR00630
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of ...
137-194 2.33e-03

excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of proteins of which all members for which functions are known except the UvrA proteins are involved in the transport of material through membranes. UvrA orthologs are involved in the recognition of DNA damage as a step in nucleotide excision repair. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273184 [Multi-domain]  Cd Length: 925  Bit Score: 41.15  E-value: 2.33e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462526932 137 LSGGQRKRLAIALEL---VNNPPVMFFDEPTSGLDSASCFQVVSLMKSLAQGGRTIICTIH 194
Cdd:TIGR00630 830 LSGGEAQRIKLAKELskrSTGRTLYILDEPTTGLHFDDIKKLLEVLQRLVDKGNTVVVIEH 890
PLN03073 PLN03073
ABC transporter F family; Provisional
137-214 3.22e-03

ABC transporter F family; Provisional


Pssm-ID: 215558 [Multi-domain]  Cd Length: 718  Bit Score: 40.61  E-value: 3.22e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 137 LSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSAScfqVVSLMKSLA--QGGrtiICTIHQPSAKLFEMFDKLYILSQGQ 214
Cdd:PLN03073  628 LSGGQKSRVAFAKITFKKPHILLLDEPSNHLDLDA---VEALIQGLVlfQGG---VLMVSHDEHLISGSVDELWVVSEGK 701
PTZ00243 PTZ00243
ABC transporter; Provisional
16-88 3.81e-03

ABC transporter; Provisional


Pssm-ID: 240327 [Multi-domain]  Cd Length: 1560  Bit Score: 40.53  E-value: 3.81e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932   16 GYKTLLKCLSGKFCRRELIGIMGPSGAGKS----TFMNIL--AGyresgmkGQILVNGRP------RELRtfRKMScYIM 83
Cdd:PTZ00243  1321 GLPLVLRGVSFRIAPREKVGIVGRTGSGKStlllTFMRMVevCG-------GEIRVNGREigayglRELR--RQFS-MIP 1390

                   ....*
gi 2462526932   84 QDDML 88
Cdd:PTZ00243  1391 QDPVL 1395
NK cd02019
Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of ...
33-52 4.54e-03

Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates to nucleosides/nucleotides, nucleoside monophosphates, or sugars. Members of this family play a wide variety of essential roles in nucleotide metabolism, the biosynthesis of coenzymes and aromatic compounds, as well as the metabolism of sugar and sulfate.


Pssm-ID: 238977 [Multi-domain]  Cd Length: 69  Bit Score: 36.16  E-value: 4.54e-03
                          10        20
                  ....*....|....*....|
gi 2462526932  33 LIGIMGPSGAGKSTFMNILA 52
Cdd:cd02019     1 IIAITGGSGSGKSTVAKKLA 20
PRK00635 PRK00635
excinuclease ABC subunit A; Provisional
120-226 5.52e-03

excinuclease ABC subunit A; Provisional


Pssm-ID: 234806 [Multi-domain]  Cd Length: 1809  Bit Score: 39.81  E-value: 5.52e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932  120 ILTALGLMSCSHTRT-ALLSGGQRKRLAIA----LELVNnppVMF-FDEPTSGLDSASCFQVVSLMKSLAQGGRTIICTI 193
Cdd:PRK00635   459 ILIDLGLPYLTPERAlATLSGGEQERTALAkhlgAELIG---ITYiLDEPSIGLHPQDTHKLINVIKKLRDQGNTVLLVE 535
                           90       100       110
                   ....*....|....*....|....*....|....
gi 2462526932  194 HQpsAKLFEMFDKLYILSQGQCIFKG-VVTNLIP 226
Cdd:PRK00635   536 HD--EQMISLADRIIDIGPGAGIFGGeVLFNGSP 567
ABC_SMC3_euk cd03272
ATP-binding cassette domain of eukaryotic SMC3 proteins; The structural maintenance of ...
137-212 6.05e-03

ATP-binding cassette domain of eukaryotic SMC3 proteins; The structural maintenance of chromosomes (SMC) proteins are large (approximately 110 to 170 kDa), and each is arranged into five recognizable domains. Amino-acid sequence homology of SMC proteins between species is largely confined to the amino- and carboxy-terminal globular domains. The amino-terminal domain contains a 'Walker A' nucleotide-binding domain (GxxGxGKS/T, in the single-letter amino-acid code), which by mutational studies has been shown to be essential in several proteins. The carboxy-terminal domain contains a sequence (the DA-box) that resembles a 'Walker B' motif, and a motif with homology to the signature sequence of the ATP-binding cassette (ABC) family of ATPases. The sequence homology within the carboxy-terminal domain is relatively high within the SMC1-SMC4 group, whereas SMC5 and SMC6 show some divergence in both of these sequences. In eukaryotic cells, the proteins are found as heterodimers of SMC1 paired with SMC3, SMC2 with SMC4, and SMC5 with SMC6 (formerly known as Rad18).


Pssm-ID: 213239 [Multi-domain]  Cd Length: 243  Bit Score: 38.78  E-value: 6.05e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462526932 137 LSGGQRKRLAIALEL----VNNPPVMFFDEPTSGLDSASCFQVVSLMKSLAQGGRtIICTIHQPsaKLFEMFDKLYILSQ 212
Cdd:cd03272   159 LSGGQKSLVALALIFaiqkCDPAPFYLFDEIDAALDAQYRTAVANMIKELSDGAQ-FITTTFRP--ELLEVADKFYGVKF 235
ATPase_flagellum-secretory_path_III cd01136
Flagellum-specific ATPase/type III secretory pathway virulence-related protein; ...
34-75 8.88e-03

Flagellum-specific ATPase/type III secretory pathway virulence-related protein; Flagellum-specific ATPase/type III secretory pathway virulence-related protein. This group of ATPases are responsible for the export of flagellum and virulence-related proteins. The bacterial flagellar motor is similar to the F0F1-ATPase, in that they both are proton-driven rotary molecular devices. However, the main function of the bacterial flagellar motor is to rotate the flagellar filament for cell motility. Intracellular pathogens such as Salmonella and Chlamydia also have proteins which are similar to the flagellar-specific ATPase, but function in the secretion of virulence-related proteins via the type III secretory pathway.


Pssm-ID: 410880 [Multi-domain]  Cd Length: 265  Bit Score: 38.31  E-value: 8.88e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 2462526932  34 IGIMGPSGAGKSTFMNILAGYRESGMKGQILVNGRPRELRTF 75
Cdd:cd01136    70 IGIFAGSGVGKSTLLGMIARNTDADVNVIALIGERGREVREF 111
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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