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Conserved domains on  [gi|2462596585|ref|XP_054205704|]
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G protein-regulated inducer of neurite outgrowth 3 isoform X1 [Homo sapiens]

Protein Classification

GRIN_C domain-containing protein( domain architecture ID 10633625)

GRIN_C domain-containing protein

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
GRIN_C pfam15235
G protein-regulated inducer of neurite outgrowth C-terminus; This represents the C-terminus of ...
651-771 7.83e-53

G protein-regulated inducer of neurite outgrowth C-terminus; This represents the C-terminus of the G protein-regulated inducer of neurite outgrowth proteins.


:

Pssm-ID: 464577  Cd Length: 130  Bit Score: 179.30  E-value: 7.83e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596585 651 AAAAQVGLTPGDKKKQLGaDSKLQLKQSKRVRDVVWDEQGMTWEVYGASLDAESLGIAIQNHLQRQIREHEKLIKTQNSQ 730
Cdd:pfam15235  10 SAEAASKLDPEVRVEDKE-EEKLAEKQKKPVRDVVWDEQGMTWEVYGASVDPEVLGMAIQKHLEKQIEEHEKLIAAQTGS 88
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 2462596585 731 TRRSISS-DTSSNKKLRGRQHSVFQSMLQNFRRPNCCVRPAP 771
Cdd:pfam15235  89 LRKSPSSgEETSPKKRKRRQPNVFRSMLQNVRRPNCCARPSP 130
PTZ00449 super family cl33186
104 kDa microneme/rhoptry antigen; Provisional
499-688 1.65e-04

104 kDa microneme/rhoptry antigen; Provisional


The actual alignment was detected with superfamily member PTZ00449:

Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 45.45  E-value: 1.65e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596585 499 TTNGHKTDPDCKLSDSCGSISKADH-----SGSLDPTNK-GDAREKKPASPQVVKEKESTGTDTSDAKTLLlNPKSQESG 572
Cdd:PTZ00449  522 KAPGDKEGEEGEHEDSKESDEPKEGgkpgeTKEGEVGKKpGPAKEHKPSKIPTLSKKPEFPKDPKHPKDPE-EPKKPKRP 600
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596585 573 GTESAANPTPSPirknqestleenrqtKTATSLSLPSDPMGDSSPGSGKKTPSRSVKASPRRPsrvsEFLKEQKLNVTAA 652
Cdd:PTZ00449  601 RSAQRPTRPKSP---------------KLPELLDIPKSPKRPESPKSPKRPPPPQRPSSPERP----EGPKIIKSPKPPK 661
                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 2462596585 653 AAQVGLTPGDKKKQLGADSKLQLKQSKRVRDVVWDE 688
Cdd:PTZ00449  662 SPKPPFDPKFKEKFYDDYLDAAAKSKETKTTVVLDE 697
PHA03247 super family cl33720
large tegument protein UL36; Provisional
50-287 9.26e-03

large tegument protein UL36; Provisional


The actual alignment was detected with superfamily member PHA03247:

Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 39.92  E-value: 9.26e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596585   50 APAEPDLSPRAAAEalmqvcEHETTQPDMSSPGVFNEVQKAPATFNSPGNPQLPGSSQPAASAPSSAAGRDLIHT--PLT 127
Cdd:PHA03247  2623 APDPPPPSPSPAAN------EPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTvgSLT 2696
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596585  128 MPANQHTCQSIPGDQPNAITSSMPEDSLMRSQRTSNREQPEKPSCPVGGVLSSSkdqvscefPSPETIQGTVQTPVTAAR 207
Cdd:PHA03247  2697 SLADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPAT--------PGGPARPARPPTTAGPPA 2768
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596585  208 VVShSSSPVGGPEGE--RQGAICDSEMRSCKPLTRESGCSENKQPSVTASGPQGTTSVTPQPTPLTSEPSACPPGPEKVP 285
Cdd:PHA03247  2769 PAP-PAAPAAGPPRRltRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPP 2847

                   ..
gi 2462596585  286 LP 287
Cdd:PHA03247  2848 PS 2849
 
Name Accession Description Interval E-value
GRIN_C pfam15235
G protein-regulated inducer of neurite outgrowth C-terminus; This represents the C-terminus of ...
651-771 7.83e-53

G protein-regulated inducer of neurite outgrowth C-terminus; This represents the C-terminus of the G protein-regulated inducer of neurite outgrowth proteins.


Pssm-ID: 464577  Cd Length: 130  Bit Score: 179.30  E-value: 7.83e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596585 651 AAAAQVGLTPGDKKKQLGaDSKLQLKQSKRVRDVVWDEQGMTWEVYGASLDAESLGIAIQNHLQRQIREHEKLIKTQNSQ 730
Cdd:pfam15235  10 SAEAASKLDPEVRVEDKE-EEKLAEKQKKPVRDVVWDEQGMTWEVYGASVDPEVLGMAIQKHLEKQIEEHEKLIAAQTGS 88
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 2462596585 731 TRRSISS-DTSSNKKLRGRQHSVFQSMLQNFRRPNCCVRPAP 771
Cdd:pfam15235  89 LRKSPSSgEETSPKKRKRRQPNVFRSMLQNVRRPNCCARPSP 130
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
499-688 1.65e-04

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 45.45  E-value: 1.65e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596585 499 TTNGHKTDPDCKLSDSCGSISKADH-----SGSLDPTNK-GDAREKKPASPQVVKEKESTGTDTSDAKTLLlNPKSQESG 572
Cdd:PTZ00449  522 KAPGDKEGEEGEHEDSKESDEPKEGgkpgeTKEGEVGKKpGPAKEHKPSKIPTLSKKPEFPKDPKHPKDPE-EPKKPKRP 600
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596585 573 GTESAANPTPSPirknqestleenrqtKTATSLSLPSDPMGDSSPGSGKKTPSRSVKASPRRPsrvsEFLKEQKLNVTAA 652
Cdd:PTZ00449  601 RSAQRPTRPKSP---------------KLPELLDIPKSPKRPESPKSPKRPPPPQRPSSPERP----EGPKIIKSPKPPK 661
                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 2462596585 653 AAQVGLTPGDKKKQLGADSKLQLKQSKRVRDVVWDE 688
Cdd:PTZ00449  662 SPKPPFDPKFKEKFYDDYLDAAAKSKETKTTVVLDE 697
PHA03247 PHA03247
large tegument protein UL36; Provisional
50-287 9.26e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 39.92  E-value: 9.26e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596585   50 APAEPDLSPRAAAEalmqvcEHETTQPDMSSPGVFNEVQKAPATFNSPGNPQLPGSSQPAASAPSSAAGRDLIHT--PLT 127
Cdd:PHA03247  2623 APDPPPPSPSPAAN------EPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTvgSLT 2696
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596585  128 MPANQHTCQSIPGDQPNAITSSMPEDSLMRSQRTSNREQPEKPSCPVGGVLSSSkdqvscefPSPETIQGTVQTPVTAAR 207
Cdd:PHA03247  2697 SLADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPAT--------PGGPARPARPPTTAGPPA 2768
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596585  208 VVShSSSPVGGPEGE--RQGAICDSEMRSCKPLTRESGCSENKQPSVTASGPQGTTSVTPQPTPLTSEPSACPPGPEKVP 285
Cdd:PHA03247  2769 PAP-PAAPAAGPPRRltRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPP 2847

                   ..
gi 2462596585  286 LP 287
Cdd:PHA03247  2848 PS 2849
 
Name Accession Description Interval E-value
GRIN_C pfam15235
G protein-regulated inducer of neurite outgrowth C-terminus; This represents the C-terminus of ...
651-771 7.83e-53

G protein-regulated inducer of neurite outgrowth C-terminus; This represents the C-terminus of the G protein-regulated inducer of neurite outgrowth proteins.


Pssm-ID: 464577  Cd Length: 130  Bit Score: 179.30  E-value: 7.83e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596585 651 AAAAQVGLTPGDKKKQLGaDSKLQLKQSKRVRDVVWDEQGMTWEVYGASLDAESLGIAIQNHLQRQIREHEKLIKTQNSQ 730
Cdd:pfam15235  10 SAEAASKLDPEVRVEDKE-EEKLAEKQKKPVRDVVWDEQGMTWEVYGASVDPEVLGMAIQKHLEKQIEEHEKLIAAQTGS 88
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 2462596585 731 TRRSISS-DTSSNKKLRGRQHSVFQSMLQNFRRPNCCVRPAP 771
Cdd:pfam15235  89 LRKSPSSgEETSPKKRKRRQPNVFRSMLQNVRRPNCCARPSP 130
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
499-688 1.65e-04

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 45.45  E-value: 1.65e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596585 499 TTNGHKTDPDCKLSDSCGSISKADH-----SGSLDPTNK-GDAREKKPASPQVVKEKESTGTDTSDAKTLLlNPKSQESG 572
Cdd:PTZ00449  522 KAPGDKEGEEGEHEDSKESDEPKEGgkpgeTKEGEVGKKpGPAKEHKPSKIPTLSKKPEFPKDPKHPKDPE-EPKKPKRP 600
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596585 573 GTESAANPTPSPirknqestleenrqtKTATSLSLPSDPMGDSSPGSGKKTPSRSVKASPRRPsrvsEFLKEQKLNVTAA 652
Cdd:PTZ00449  601 RSAQRPTRPKSP---------------KLPELLDIPKSPKRPESPKSPKRPPPPQRPSSPERP----EGPKIIKSPKPPK 661
                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 2462596585 653 AAQVGLTPGDKKKQLGADSKLQLKQSKRVRDVVWDE 688
Cdd:PTZ00449  662 SPKPPFDPKFKEKFYDDYLDAAAKSKETKTTVVLDE 697
PHA03247 PHA03247
large tegument protein UL36; Provisional
50-287 9.26e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 39.92  E-value: 9.26e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596585   50 APAEPDLSPRAAAEalmqvcEHETTQPDMSSPGVFNEVQKAPATFNSPGNPQLPGSSQPAASAPSSAAGRDLIHT--PLT 127
Cdd:PHA03247  2623 APDPPPPSPSPAAN------EPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTvgSLT 2696
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596585  128 MPANQHTCQSIPGDQPNAITSSMPEDSLMRSQRTSNREQPEKPSCPVGGVLSSSkdqvscefPSPETIQGTVQTPVTAAR 207
Cdd:PHA03247  2697 SLADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPAT--------PGGPARPARPPTTAGPPA 2768
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596585  208 VVShSSSPVGGPEGE--RQGAICDSEMRSCKPLTRESGCSENKQPSVTASGPQGTTSVTPQPTPLTSEPSACPPGPEKVP 285
Cdd:PHA03247  2769 PAP-PAAPAAGPPRRltRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPP 2847

                   ..
gi 2462596585  286 LP 287
Cdd:PHA03247  2848 PS 2849
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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