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Conserved domains on  [gi|2462576050|ref|XP_054199358|]
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tetratricopeptide repeat protein 31 isoform X5 [Homo sapiens]

Protein Classification

tetratricopeptide repeat protein( domain architecture ID 708416)

tetratricopeptide repeat (TPR) protein may adopt a right-handed helical structure with an amphipathic channel and may function as an interaction scaffold in the formation of multi-protein complexes

CATH:  1.25.40.10
Gene Ontology:  GO:0005515
PubMed:  10517866|30708253
SCOP:  3001345

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Spy super family cl27809
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 119-332 2.01e-13

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


The actual alignment was detected with superfamily member COG3914:

Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 71.95  E-value: 2.01e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462576050 119 QGRGLALQKMGQEEESPPREERPQQSPKVQEKDLGRLRPQDLLDFAPYPQASPGLLAAALQQSQE-----------LAKL 187
Cdd:COG3914    39 AALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLLQALGRYEEALALYRRalalnpdnaeaLFNL 118

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462576050 188 GTSFAQNGFYHEAVVLFTQALKLNPQDHRLFGNRSFCHERLGQPAWALADAQVALTLRPGWPRGLFRLGKALMGLQRFRE 267
Cdd:COG3914   119 GNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEE 198

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2462576050 268 AAAVFQETLRggSQPDAArELRSCLLHLTLQGQRGGICAPPLSPGALQPLPHAELAPSGLPSLRC 332
Cdd:COG3914   199 AIAAYRRALE--LDPDNA-DAHSNLLFALRQACDWEVYDRFEELLAALARGPSELSPFALLYLPD 260
 
Name Accession Description Interval E-value
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 119-332 2.01e-13

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 71.95  E-value: 2.01e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462576050 119 QGRGLALQKMGQEEESPPREERPQQSPKVQEKDLGRLRPQDLLDFAPYPQASPGLLAAALQQSQE-----------LAKL 187
Cdd:COG3914    39 AALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLLQALGRYEEALALYRRalalnpdnaeaLFNL 118

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462576050 188 GTSFAQNGFYHEAVVLFTQALKLNPQDHRLFGNRSFCHERLGQPAWALADAQVALTLRPGWPRGLFRLGKALMGLQRFRE 267
Cdd:COG3914   119 GNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEE 198

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2462576050 268 AAAVFQETLRggSQPDAArELRSCLLHLTLQGQRGGICAPPLSPGALQPLPHAELAPSGLPSLRC 332
Cdd:COG3914   199 AIAAYRRALE--LDPDNA-DAHSNLLFALRQACDWEVYDRFEELLAALARGPSELSPFALLYLPD 260
PLN03088 PLN03088
SGT1, suppressor of G2 allele of SKP1; Provisional
 200-273 2.89e-07

SGT1, suppressor of G2 allele of SKP1; Provisional


Pssm-ID: 215568 [Multi-domain]  Cd Length: 356  Bit Score: 52.10  E-value: 2.89e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2462576050 200 AVVLFTQALKLNPQDHRLFGNRSFCHERLGQPAWALADAQVALTLRPGWPRGLFRLGKALMGLQRFREAAAVFQ 273
Cdd:PLN03088   21 AVDLYTQAIDLDPNNAELYADRAQANIKLGNFTEAVADANKAIELDPSLAKAYLRKGTACMKLEEYQTAKAALE 94
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 184-268 5.60e-07

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 51.52  E-value: 5.60e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462576050 184 LAKLGTSFAQNGFYHEAVVLFTQALKLNPqDHRLFGNRSFCHERLGQPAWALADAQVALTLRPGWPRGLFRLGKALMGLQ 263
Cdd:TIGR00990 130 LKEKGNKAYRNKDFNKAIKLYSKAIECKP-DPVYYSNRAACHNALGDWEKVVEDTTAALELDPDYSKALNRRANAYDGLG 208


                  ....*
gi 2462576050 264 RFREA 268
Cdd:TIGR00990 209 KYADA 213
 
Name Accession Description Interval E-value
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 119-332 2.01e-13

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 71.95  E-value: 2.01e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462576050 119 QGRGLALQKMGQEEESPPREERPQQSPKVQEKDLGRLRPQDLLDFAPYPQASPGLLAAALQQSQE-----------LAKL 187
Cdd:COG3914    39 AALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLLQALGRYEEALALYRRalalnpdnaeaLFNL 118

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462576050 188 GTSFAQNGFYHEAVVLFTQALKLNPQDHRLFGNRSFCHERLGQPAWALADAQVALTLRPGWPRGLFRLGKALMGLQRFRE 267
Cdd:COG3914   119 GNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEE 198

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2462576050 268 AAAVFQETLRggSQPDAArELRSCLLHLTLQGQRGGICAPPLSPGALQPLPHAELAPSGLPSLRC 332
Cdd:COG3914   199 AIAAYRRALE--LDPDNA-DAHSNLLFALRQACDWEVYDRFEELLAALARGPSELSPFALLYLPD 260
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
184-294 2.67e-13

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 69.27  E-value: 2.67e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462576050 184 LAKLGTSFAQNGFYHEAVVLFTQALKLNPQDHRLFGNRSFCHERLGQPAWALADAQVALTLRPGWPRGLFRLGKALMGLQ 263
Cdd:COG0457    45 LYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELG 124

                          90       100       110
                  ....*....|....*....|....*....|.
gi 2462576050 264 RFREAAAVFQETLRGGSQPDAARELRSCLLH 294
Cdd:COG0457   125 RYDEAIEAYERALELDPDDADALYNLGIALE 155
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
184-295 5.64e-13

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 68.11  E-value: 5.64e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462576050 184 LAKLGTSFAQNGFYHEAVVLFTQALKLNPQDHRLFGNRSFCHERLGQPAWALADAQVALTLRPGWPRGLFRLGKALMGLQ 263
Cdd:COG0457    11 YNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALG 90

                          90       100       110
                  ....*....|....*....|....*....|...
gi 2462576050 264 RFREAAAVFQETLRGGSQ-PDAARELRSCLLHL 295
Cdd:COG0457    91 RYEEALEDYDKALELDPDdAEALYNLGLALLEL 123
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
184-290 8.56e-13

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 67.72  E-value: 8.56e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462576050 184 LAKLGTSFAQNGFYHEAVVLFTQALKLNPQDHRLFGNRSFCHERLGQPAWALADAQVALTLRPGWPRGLFRLGKALMGLQ 263
Cdd:COG0457    79 LNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLG 158

                          90       100
                  ....*....|....*....|....*..
gi 2462576050 264 RFREAAAVFQETLRGGSQPDAARELRS 290
Cdd:COG0457   159 RYEEALELLEKLEAAALAALLAAALGE 185
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 173-277 1.14e-12

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 64.83  E-value: 1.14e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462576050 173 LLAAALQQSQE----LAKLGTSFAQNGFYHEAVVLFTQALKLNPQDHRLFGNRSFCHERLGQPAWALADAQVALTLRPGW 248
Cdd:COG4783    26 LLEKALELDPDnpeaFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALKLDPEH 105

                          90       100
                  ....*....|....*....|....*....
gi 2462576050 249 PRGLFRLGKALMGLQRFREAAAVFQETLR 277
Cdd:COG4783   106 PEAYLRLARAYRALGRPDEAIAALEKALE 134
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 152-277 2.47e-12

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 64.21  E-value: 2.47e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462576050 152 LGRLRPQDLLDFAPYPQASPGLLAAALQQSQELAKLGTSFAQNGFYHEAVVLFTQALKLNPQDHRLFGNRSFCHERLGQP 231
Cdd:COG5010    25 EKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDK 104

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 2462576050 232 AWALADAQVALTLRPGWPRGLFRLGKALMGLQRFREAAAVFQETLR 277
Cdd:COG5010   105 DEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALG 150
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
155-297 6.19e-12

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 64.55  E-value: 6.19e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462576050 155 LRPQDLLDFAPYpQASPGLLAAALQQSQELAKLGTSFAQNGFYHEAVVLFTQALKLNPQDHRLFGNRSFCHERLGQPAWA 234
Cdd:COG4785    48 LAAAALAAAALA-AERIDRALALPDLAQLYYERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAA 126

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2462576050 235 LADAQVALTLRPGWPRGLFRLGKALMGLQRFREAAAVFQETLRgGSQPDAARELRSCLLHLTL 297
Cdd:COG4785   127 LEDFDRALELDPDYAYAYLNRGIALYYLGRYELAIADLEKALE-LDPNDPERALWLYLAERKL 188
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 174-290 2.36e-10

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 58.09  E-value: 2.36e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462576050 174 LAAALQQSQE----LAKLGTSFAQNGFYHEAVVLFTQALKLNPQDHRLFGNRSFCHERLGQPAWALADAQVALTLRPGWP 249
Cdd:COG4235     6 LRQALAANPNdaegWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNP 85

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 2462576050 250 RGLFRLGKALMGLQRFREAAAVFQETLRGGSQPDAARELRS 290
Cdd:COG4235    86 EALYLLGLAAFQQGDYAEAIAAWQKLLALLPADAPARLLEA 126
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 179-295 2.52e-10

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 58.28  E-value: 2.52e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462576050 179 QQSQELAKLGTSFAQNGFYHEAVVLFTQALKLNPQDHRLFGNRSFCHERLGQPAWALADAQVALTLRPGWPRGLFRLGKA 258
Cdd:COG4783     2 ACAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLA 81

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 2462576050 259 LMGLQRFREAAAVFQETLR-GGSQPDAARELRSCLLHL 295
Cdd:COG4783    82 LLKAGDYDEALALLEKALKlDPEHPEAYLRLARAYRAL 119
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
191-286 2.39e-09

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 54.02  E-value: 2.39e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462576050 191 FAQNGFYHEAVVLFTQALKLNPQDHRLFGNRSFCHERLGQPAWALAdAQVALTLRPGWPRGLFRLGKALMGLQRFREAAA 270
Cdd:COG3063     2 YLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEALA 80

                          90
                  ....*....|....*.
gi 2462576050 271 VFQETLRggSQPDAAR 286
Cdd:COG3063    81 YLERALE--LDPSALR 94
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
208-277 2.25e-08

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 54.63  E-value: 2.25e-08
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462576050 208 LKLNPQDHRLFGNRSFCHERLGQPAWALADAQVALTLRPGWPRGLFRLGKALMGLQRFREAAAVFQETLR 277
Cdd:COG0457     1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALE 70
PLN03088 PLN03088
SGT1, suppressor of G2 allele of SKP1; Provisional
 200-273 2.89e-07

SGT1, suppressor of G2 allele of SKP1; Provisional


Pssm-ID: 215568 [Multi-domain]  Cd Length: 356  Bit Score: 52.10  E-value: 2.89e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2462576050 200 AVVLFTQALKLNPQDHRLFGNRSFCHERLGQPAWALADAQVALTLRPGWPRGLFRLGKALMGLQRFREAAAVFQ 273
Cdd:PLN03088   21 AVDLYTQAIDLDPNNAELYADRAQANIKLGNFTEAVADANKAIELDPSLAKAYLRKGTACMKLEEYQTAKAALE 94
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 173-295 3.43e-07

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 51.27  E-value: 3.43e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462576050 173 LLAAALQQSQELAKLGTSFAQNGFYHEAVVLFTQALKLNPQDHRLFGNRSFCHERLGQPAWALADAQVALTLRPGWPRGL 252
Cdd:COG2956   136 LLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPAL 215

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 2462576050 253 FRLGKALMGLQRFREAAAVFQETLRGGSQPDAARELRSCLLHL 295
Cdd:COG2956   216 PRLAELYEKLGDPEEALELLRKALELDPSDDLLLALADLLERK 258
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 184-268 5.60e-07

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 51.52  E-value: 5.60e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462576050 184 LAKLGTSFAQNGFYHEAVVLFTQALKLNPqDHRLFGNRSFCHERLGQPAWALADAQVALTLRPGWPRGLFRLGKALMGLQ 263
Cdd:TIGR00990 130 LKEKGNKAYRNKDFNKAIKLYSKAIECKP-DPVYYSNRAACHNALGDWEKVVEDTTAALELDPDYSKALNRRANAYDGLG 208


                  ....*
gi 2462576050 264 RFREA 268
Cdd:TIGR00990 209 KYADA 213
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 173-295 7.78e-07

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 50.11  E-value: 7.78e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462576050 173 LLAAALQQSQELAKLGTSFAQNGFYHEAVVLFTQALKLNPQDHRLFGNRSFCHERLGQPAWALADAQVALTLRPGWPRGL 252
Cdd:COG2956   102 LLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARAL 181

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 2462576050 253 FRLGKALMGLQRFREAAAVFQETLRggSQPD---AARELRSCLLHL 295
Cdd:COG2956   182 LLLAELYLEQGDYEEAIAALERALE--QDPDylpALPRLAELYEKL 225
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 199-277 1.72e-06

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 46.92  E-value: 1.72e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2462576050 199 EAVVLFTQALKLNPQDHRLFGNRSFCHERLGQPAWALADAQVALTLRPGWPRGLFRLGKALMGLQRFREAAAVFQETLR 277
Cdd:COG4235     1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALA 79
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 173-286 2.72e-06

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 48.57  E-value: 2.72e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462576050 173 LLAAALQQSQELAKLGTSFAQNGFYHEAVVLFTQALKLNPQDHRLFGNRSFCHERLGQPAWALADAQVALTLRPGWPRGL 252
Cdd:COG2956    68 LLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAY 147

                          90       100       110
                  ....*....|....*....|....*....|....
gi 2462576050 253 FRLGKALMGLQRFREAAAVFQETLRggSQPDAAR 286
Cdd:COG2956   148 CELAELYLEQGDYDEAIEALEKALK--LDPDCAR 179
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 166-246 5.48e-05

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 42.87  E-value: 5.48e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462576050 166 YPQASPGLLAAALQQSQE---LAKLGTSFAQNGFYHEAVVLFTQALKLNPQDHRLFGNRSFCHERLGQPAWALADAQVAL 242
Cdd:COG4783    54 LDEAIVLLHEALELDPDEpeaRLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKAL 133


                  ....
gi 2462576050 243 TLRP 246
Cdd:COG4783   134 ELDP 137
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 187-246 8.52e-05

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 42.64  E-value: 8.52e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462576050 187 LGTSFAQNGFYHEAVVLFTQALKLNPQDHRLFGNRSFCHERLGQPAWALADAQVALTLRP 246
Cdd:COG5010    94 LALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 173-293 1.35e-04

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 43.18  E-value: 1.35e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462576050 173 LLAAALQQSQELAKlGTSFAQNGFYHEAVVLFTQALKLNPQD---HRLFGNrsfCHERLGQPAWALADAQVALTLRPGWP 249
Cdd:COG2956     1 LLLPVAAALGWYFK-GLNYLLNGQPDKAIDLLEEALELDPETveaHLALGN---LYRRRGEYDRAIRIHQKLLERDPDRA 76

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 2462576050 250 RGLFRLGKALMGLQRFREAAAVFQETLR-GGSQPDAARELRSCLL 293
Cdd:COG2956    77 EALLELAQDYLKAGLLDRAEELLEKLLElDPDDAEALRLLAEIYE 121
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 190-287 2.78e-04

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 39.97  E-value: 2.78e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462576050 190 SFAQNGFYHEAVVLFTQALKLNPqDHRLFGNRSF----CHERLGQPAWALADAQVALTLRPGW---PRGLFRLGKALMGL 262
Cdd:COG1729     2 ALLKAGDYDEAIAAFKAFLKRYP-NSPLAPDALYwlgeAYYALGDYDEAAEAFEKLLKRYPDSpkaPDALLKLGLSYLEL 80

                          90       100
                  ....*....|....*....|....*
gi 2462576050 263 QRFREAAAVFQETLRGGSQPDAARE 287
Cdd:COG1729    81 GDYDKARATLEELIKKYPDSEAAKE 105
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 173-288 4.79e-04

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 41.64  E-value: 4.79e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462576050 173 LLAAALQQSQELA----KLGTSFAQNGFYHEAVVLFTQALKLNPQDHRLFGNRSFCHERLGQPAWALADAQVALTLRPGW 248
Cdd:COG2956    30 LLEEALELDPETVeahlALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDD 109

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 2462576050 249 PRGLFRLGKALMGLQRFREAAAVFQETLR-GGSQPDAAREL 288
Cdd:COG2956   110 AEALRLLAEIYEQEGDWEKAIEVLERLLKlGPENAHAYCEL 150
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
184-315 5.25e-04

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 41.15  E-value: 5.25e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462576050 184 LAKLGTSFAQNGFYHEAVVLFTQALKLNPQDHRLFGNRSFCHERLGQPAWALADAQVALTLRPGWPRGLfRLGKALMGLQ 263
Cdd:COG0457   113 LYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEAAALAALLAA-ALGEAALALA 191

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2462576050 264 RFREAAAVFQETLRGGSQPDAARELRSCLLHLTLQGQRGGICAPPLSPGALQ 315
Cdd:COG0457   192 AAEVLLALLLALEQALRKKLAILTLAALAELLLLALALLLALRLAALALYQY 243
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
224-277 8.94e-04

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 38.23  E-value: 8.94e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2462576050 224 CHERLGQPAWALADAQVALTLRPGWPRGLFRLGKALMGLQRFREAAAvFQETLR 277
Cdd:COG3063     1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALK 53
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 162-295 3.21e-03

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 38.02  E-value: 3.21e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462576050 162 DFAPYPQASPGLLAAALQQSQELAKLGTSFAQNGFYHEAVVLFTQALKLNPQDHRLFGNRSFCHERLGQPAWALADAQVA 241
Cdd:COG5010     1 ARALEGFDRLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQA 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2462576050 242 LTLRPGWPRGLFRLGKALMGLQRFREAAAVFQETLR-GGSQPDAARELRSCLLHL 295
Cdd:COG5010    81 LQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALAlSPDNPNAYSNLAALLLSL 135
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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