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Conserved domains on  [gi|2462569067|ref|XP_054196010|]
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TRAF family member-associated NF-kappa-B activator isoform X2 [Homo sapiens]

Protein Classification

TBD domain-containing protein( domain architecture ID 10582370)

TBD domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TBD pfam12845
TBD domain; The Tbk1/Ikki binding domain (TBD) is a 40 amino acid domain able to bind kinases, ...
 240-293 4.07e-24

TBD domain; The Tbk1/Ikki binding domain (TBD) is a 40 amino acid domain able to bind kinases, has been found to be essential for poly(I:C)-induced IRF activation. The domain is found in SINTBAD, TANK and NAP1 protein. This domain is predicted to form an a-helix with residues essential for kinase binding clustering on one side.


:

Pssm-ID: 463729 [Multi-domain]  Cd Length: 56  Bit Score: 95.19  E-value: 4.07e-24
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2462569067 240 HERGNIEKTFWDLKEEFHKICMLAKAQKDHLSKLNI-PDTATETQCSVPIQCTDK 293
Cdd:pfam12845   2 DSSVNLEKAYWELKEEMHRLCMLTRVQAEHLRKLKIeQETAGEIQFSMPIQCTDD 56
 
Name Accession Description Interval E-value
TBD pfam12845
TBD domain; The Tbk1/Ikki binding domain (TBD) is a 40 amino acid domain able to bind kinases, ...
 240-293 4.07e-24

TBD domain; The Tbk1/Ikki binding domain (TBD) is a 40 amino acid domain able to bind kinases, has been found to be essential for poly(I:C)-induced IRF activation. The domain is found in SINTBAD, TANK and NAP1 protein. This domain is predicted to form an a-helix with residues essential for kinase binding clustering on one side.


Pssm-ID: 463729 [Multi-domain]  Cd Length: 56  Bit Score: 95.19  E-value: 4.07e-24
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2462569067 240 HERGNIEKTFWDLKEEFHKICMLAKAQKDHLSKLNI-PDTATETQCSVPIQCTDK 293
Cdd:pfam12845   2 DSSVNLEKAYWELKEEMHRLCMLTRVQAEHLRKLKIeQETAGEIQFSMPIQCTDD 56
 
Name Accession Description Interval E-value
TBD pfam12845
TBD domain; The Tbk1/Ikki binding domain (TBD) is a 40 amino acid domain able to bind kinases, ...
 240-293 4.07e-24

TBD domain; The Tbk1/Ikki binding domain (TBD) is a 40 amino acid domain able to bind kinases, has been found to be essential for poly(I:C)-induced IRF activation. The domain is found in SINTBAD, TANK and NAP1 protein. This domain is predicted to form an a-helix with residues essential for kinase binding clustering on one side.


Pssm-ID: 463729 [Multi-domain]  Cd Length: 56  Bit Score: 95.19  E-value: 4.07e-24
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2462569067 240 HERGNIEKTFWDLKEEFHKICMLAKAQKDHLSKLNI-PDTATETQCSVPIQCTDK 293
Cdd:pfam12845   2 DSSVNLEKAYWELKEEMHRLCMLTRVQAEHLRKLKIeQETAGEIQFSMPIQCTDD 56
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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