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Conserved domains on  [gi|2462499489|ref|XP_054189242|]
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protein sel-1 homolog 2 isoform X6 [Homo sapiens]

Protein Classification

tetratricopeptide repeat protein( domain architecture ID 11434433)

tetratricopeptide repeat (TPR) protein may adopt a right-handed helical structure with an amphipathic channel and may function as an interaction scaffold in the formation of multi-protein complexes

CATH:  1.25.40.10
Gene Ontology:  GO:0005515
PubMed:  10517866|30708253
SCOP:  3001345

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TPR COG0790
TPR repeat [General function prediction only];
197-391 9.75e-46

TPR repeat [General function prediction only];


:

Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 161.63  E-value: 9.75e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462499489 197 WDIYQYYKFLAERGDVQIQVSLGQLHLIGRkGLDQDYYKALHYFLKAAKAGSANAMAFIGKMYLEGNAaVPQNNATAFKY 276
Cdd:COG0790    48 AAAAAAAAAAAAAGGAEAQYNLGLMYAEGR-GVPKDYEKALEWFEKAAEQGDAEAQYNLGLMYEEGLG-VPQDYAKALEW 125

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462499489 277 FSMAASKGNAIGLHGLGLLYFHGKGVPLNYAEALKYFQKAAEKGWPDAQFQLGFMYYSGSGIWKDYKLAFKYFYLASQSG 356
Cdd:COG0790   126 YEKAAEQGDADAQYNLGLLYLNGEGVPKDPAKAAEWYRKAAEQGDADAQYNLGVLYENGRGVPKDPAKALEWYRKAAEQG 205

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 2462499489 357 QPLAIYYLAKMYATGTGVVRSCRTAVELYKGVCEL 391
Cdd:COG0790   206 DADAQYNLGRLYLNGEGVEKDLEKALRWLRKAAEQ 240
TPR COG0790
TPR repeat [General function prediction only];
39-246 4.36e-18

TPR repeat [General function prediction only];


:

Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 83.82  E-value: 4.36e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462499489  39 QKQKEEAYLLFAKAADMGNLKAMEKMADALLFGNFGVQNITAAIQLYESLAKEGSCKAQNALGFLSSYGIGMEYDQAKAL 118
Cdd:COG0790    80 PKDYEKALEWFEKAAEQGDAEAQYNLGLMYEEGLGVPQDYAKALEWYEKAAEQGDADAQYNLGLLYLNGEGVPKDPAKAA 159

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462499489 119 IYYTFGSAGGNMMSQMILGYRYLSGINVLQNCEVALSYYKKVadyiadtfeksegvpvekvrlterpenlssnseildwd 198
Cdd:COG0790   160 EWYRKAAEQGDADAQYNLGVLYENGRGVPKDPAKALEWYRKA-------------------------------------- 201

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 2462499489 199 iyqyykflAERGDVQIQVSLGQLHLIGRkGLDQDYYKALHYFLKAAKA 246
Cdd:COG0790   202 --------AEQGDADAQYNLGRLYLNGE-GVEKDLEKALRWLRKAAEQ 240
TPR COG0790
TPR repeat [General function prediction only];
413-535 1.68e-12

TPR repeat [General function prediction only];


:

Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 67.65  E-value: 1.68e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462499489 413 SLVQYALLAEMGYEVAQSNSAFILESKKANILEKEKMYPMALLLWNRAAIQGNAFARVKIGDYHYYGYGTKKDYQTAATH 492
Cdd:COG0790    10 AAAAAAAALAAAAAAAGAAAAAAAAAAAAAALAAAAGAAAAAAAAAAAAAAGGAEAQYNLGLMYAEGRGVPKDYEKALEW 89

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 2462499489 493 YSIAANKyHNAQAMFNLAYMYEHGLGITKDIHLARRLYDMAAQ 535
Cdd:COG0790    90 FEKAAEQ-GDAEAQYNLGLMYEEGLGVPQDYAKALEWYEKAAE 131
 
Name Accession Description Interval E-value
TPR COG0790
TPR repeat [General function prediction only];
197-391 9.75e-46

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 161.63  E-value: 9.75e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462499489 197 WDIYQYYKFLAERGDVQIQVSLGQLHLIGRkGLDQDYYKALHYFLKAAKAGSANAMAFIGKMYLEGNAaVPQNNATAFKY 276
Cdd:COG0790    48 AAAAAAAAAAAAAGGAEAQYNLGLMYAEGR-GVPKDYEKALEWFEKAAEQGDAEAQYNLGLMYEEGLG-VPQDYAKALEW 125

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462499489 277 FSMAASKGNAIGLHGLGLLYFHGKGVPLNYAEALKYFQKAAEKGWPDAQFQLGFMYYSGSGIWKDYKLAFKYFYLASQSG 356
Cdd:COG0790   126 YEKAAEQGDADAQYNLGLLYLNGEGVPKDPAKAAEWYRKAAEQGDADAQYNLGVLYENGRGVPKDPAKALEWYRKAAEQG 205

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 2462499489 357 QPLAIYYLAKMYATGTGVVRSCRTAVELYKGVCEL 391
Cdd:COG0790   206 DADAQYNLGRLYLNGEGVEKDLEKALRWLRKAAEQ 240
TPR COG0790
TPR repeat [General function prediction only];
39-246 4.36e-18

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 83.82  E-value: 4.36e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462499489  39 QKQKEEAYLLFAKAADMGNLKAMEKMADALLFGNFGVQNITAAIQLYESLAKEGSCKAQNALGFLSSYGIGMEYDQAKAL 118
Cdd:COG0790    80 PKDYEKALEWFEKAAEQGDAEAQYNLGLMYEEGLGVPQDYAKALEWYEKAAEQGDADAQYNLGLLYLNGEGVPKDPAKAA 159

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462499489 119 IYYTFGSAGGNMMSQMILGYRYLSGINVLQNCEVALSYYKKVadyiadtfeksegvpvekvrlterpenlssnseildwd 198
Cdd:COG0790   160 EWYRKAAEQGDADAQYNLGVLYENGRGVPKDPAKALEWYRKA-------------------------------------- 201

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 2462499489 199 iyqyykflAERGDVQIQVSLGQLHLIGRkGLDQDYYKALHYFLKAAKA 246
Cdd:COG0790   202 --------AEQGDADAQYNLGRLYLNGE-GVEKDLEKALRWLRKAAEQ 240
TPR COG0790
TPR repeat [General function prediction only];
413-535 1.68e-12

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 67.65  E-value: 1.68e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462499489 413 SLVQYALLAEMGYEVAQSNSAFILESKKANILEKEKMYPMALLLWNRAAIQGNAFARVKIGDYHYYGYGTKKDYQTAATH 492
Cdd:COG0790    10 AAAAAAAALAAAAAAAGAAAAAAAAAAAAAALAAAAGAAAAAAAAAAAAAAGGAEAQYNLGLMYAEGRGVPKDYEKALEW 89

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 2462499489 493 YSIAANKyHNAQAMFNLAYMYEHGLGITKDIHLARRLYDMAAQ 535
Cdd:COG0790    90 FEKAAEQ-GDAEAQYNLGLMYEEGLGVPQDYAKALEWYEKAAE 131
SEL1 smart00671
Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.
 503-535 3.26e-06

Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.


Pssm-ID: 214772 [Multi-domain]  Cd Length: 36  Bit Score: 44.09  E-value: 3.26e-06
                           10        20        30
                   ....*....|....*....|....*....|...
gi 2462499489  503 AQAMFNLAYMYEHGLGITKDIHLARRLYDMAAQ 535
Cdd:smart00671   1 AEAQYNLGQMYEYGLGVPKDLEKALEYYKKAAE 33
Sel1 pfam08238
Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.
 503-535 3.65e-06

Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.


Pssm-ID: 429881 [Multi-domain]  Cd Length: 35  Bit Score: 43.66  E-value: 3.65e-06
                          10        20        30
                  ....*....|....*....|....*....|...
gi 2462499489 503 AQAMFNLAYMYEHGLGITKDIHLARRLYDMAAQ 535
Cdd:pfam08238   1 AEAQYRLGYLYLYGLGVPKDPEKALEWYEKAAE 33
SEL1 smart00671
Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.
 322-356 4.73e-06

Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.


Pssm-ID: 214772 [Multi-domain]  Cd Length: 36  Bit Score: 43.32  E-value: 4.73e-06
                           10        20        30
                   ....*....|....*....|....*....|....*
gi 2462499489  322 PDAQFQLGFMYYSGSGIWKDYKLAFKYFYLASQSG 356
Cdd:smart00671   1 AEAQYNLGQMYEYGLGVPKDLEKALEYYKKAAELG 35
Sel1 pfam08238
Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.
 286-320 1.56e-05

Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.


Pssm-ID: 429881 [Multi-domain]  Cd Length: 35  Bit Score: 42.12  E-value: 1.56e-05
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 2462499489 286 AIGLHGLGLLYFHGKGVPLNYAEALKYFQKAAEKG 320
Cdd:pfam08238   1 AEAQYRLGYLYLYGLGVPKDPEKALEWYEKAAELG 35
 
Name Accession Description Interval E-value
TPR COG0790
TPR repeat [General function prediction only];
197-391 9.75e-46

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 161.63  E-value: 9.75e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462499489 197 WDIYQYYKFLAERGDVQIQVSLGQLHLIGRkGLDQDYYKALHYFLKAAKAGSANAMAFIGKMYLEGNAaVPQNNATAFKY 276
Cdd:COG0790    48 AAAAAAAAAAAAAGGAEAQYNLGLMYAEGR-GVPKDYEKALEWFEKAAEQGDAEAQYNLGLMYEEGLG-VPQDYAKALEW 125

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462499489 277 FSMAASKGNAIGLHGLGLLYFHGKGVPLNYAEALKYFQKAAEKGWPDAQFQLGFMYYSGSGIWKDYKLAFKYFYLASQSG 356
Cdd:COG0790   126 YEKAAEQGDADAQYNLGLLYLNGEGVPKDPAKAAEWYRKAAEQGDADAQYNLGVLYENGRGVPKDPAKALEWYRKAAEQG 205

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 2462499489 357 QPLAIYYLAKMYATGTGVVRSCRTAVELYKGVCEL 391
Cdd:COG0790   206 DADAQYNLGRLYLNGEGVEKDLEKALRWLRKAAEQ 240
TPR COG0790
TPR repeat [General function prediction only];
231-393 1.89e-37

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 139.29  E-value: 1.89e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462499489 231 QDYYKALHYFLKAAKAGSANAMAFIGKMYLEGNAaVPQNNATAFKYFSMAASKGNAIGLHGLGLLYFHGKGVPLNYAEAL 310
Cdd:COG0790    45 AGAAAAAAAAAAAAAAGGAEAQYNLGLMYAEGRG-VPKDYEKALEWFEKAAEQGDAEAQYNLGLMYEEGLGVPQDYAKAL 123

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462499489 311 KYFQKAAEKGWPDAQFQLGFMYYSGSGIWKDYKLAFKYFYLASQSGQPLAIYYLAKMYATGTGVVRSCRTAVELYKGVCE 390
Cdd:COG0790   124 EWYEKAAEQGDADAQYNLGLLYLNGEGVPKDPAKAAEWYRKAAEQGDADAQYNLGVLYENGRGVPKDPAKALEWYRKAAE 203


                  ...
gi 2462499489 391 LGH 393
Cdd:COG0790   204 QGD 206
TPR COG0790
TPR repeat [General function prediction only];
241-535 1.24e-35

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 134.29  E-value: 1.24e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462499489 241 LKAAKAGSANAMAFIGKMYLEGNAAVPQNNATAFKYFSMAASKGNAIGLHGLGLLYFHGKGVPLNYAEALKYFQKAAEKG 320
Cdd:COG0790    18 LAAAAAAAGAAAAAAAAAAAAAALAAAAGAAAAAAAAAAAAAAGGAEAQYNLGLMYAEGRGVPKDYEKALEWFEKAAEQG 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462499489 321 WPDAQFQLGFMYYSGSGIWKDYKLAFKYFYLASQSGQPLAIYYLAKMYATGTGVVRSCRTAVELYKgvcelghwaekflt 400
Cdd:COG0790    98 DAEAQYNLGLMYEEGLGVPQDYAKALEWYEKAAEQGDADAQYNLGLLYLNGEGVPKDPAKAAEWYR-------------- 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462499489 401 ayfaykdgdidsslvqyallaemgyevaqsnsafileskkanilekekmypmalllwnRAAIQGNAFARVKIGDYHYYGY 480
Cdd:COG0790   164 ----------------------------------------------------------KAAEQGDADAQYNLGVLYENGR 185

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2462499489 481 GTKKDYQTAATHYSIAANKyHNAQAMFNLAYMYEHGLGITKDIHLARRLYDMAAQ 535
Cdd:COG0790   186 GVPKDPAKALEWYRKAAEQ-GDADAQYNLGRLYLNGEGVEKDLEKALRWLRKAAE 239
TPR COG0790
TPR repeat [General function prediction only];
43-352 2.41e-31

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 121.96  E-value: 2.41e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462499489  43 EEAYLLFAKAADMGNLKAMEKMADALLFGNFGVQNITAAIQLYESLAKEGSCKAQNALGFLSSYGIGMEYDQAKALIYYT 122
Cdd:COG0790    12 AAAAAALAAAAAAAGAAAAAAAAAAAAAALAAAAGAAAAAAAAAAAAAAGGAEAQYNLGLMYAEGRGVPKDYEKALEWFE 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462499489 123 FGSAGGNMMSQMILGYRYLSGinvlqncevalsyykkvadyiadtfeksegvpvekvrlterpenlssnseildwdiyqy 202
Cdd:COG0790    92 KAAEQGDAEAQYNLGLMYEEG----------------------------------------------------------- 112

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462499489 203 ykflaergdvqiqvslgqlhligrKGLDQDYYKALHYFLKAAKAGSANAMAFIGKMYLEGNaAVPQNNATAFKYFSMAAS 282
Cdd:COG0790   113 ------------------------LGVPQDYAKALEWYEKAAEQGDADAQYNLGLLYLNGE-GVPKDPAKAAEWYRKAAE 167

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462499489 283 KGNAIGLHGLGLLYFHGKGVPLNYAEALKYFQKAAEKGWPDAQFQLGFMYYSGSGIWKDYKLAFKYFYLA 352
Cdd:COG0790   168 QGDADAQYNLGVLYENGRGVPKDPAKALEWYRKAAEQGDADAQYNLGRLYLNGEGVEKDLEKALRWLRKA 237
TPR COG0790
TPR repeat [General function prediction only];
39-246 4.36e-18

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 83.82  E-value: 4.36e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462499489  39 QKQKEEAYLLFAKAADMGNLKAMEKMADALLFGNFGVQNITAAIQLYESLAKEGSCKAQNALGFLSSYGIGMEYDQAKAL 118
Cdd:COG0790    80 PKDYEKALEWFEKAAEQGDAEAQYNLGLMYEEGLGVPQDYAKALEWYEKAAEQGDADAQYNLGLLYLNGEGVPKDPAKAA 159

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462499489 119 IYYTFGSAGGNMMSQMILGYRYLSGINVLQNCEVALSYYKKVadyiadtfeksegvpvekvrlterpenlssnseildwd 198
Cdd:COG0790   160 EWYRKAAEQGDADAQYNLGVLYENGRGVPKDPAKALEWYRKA-------------------------------------- 201

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 2462499489 199 iyqyykflAERGDVQIQVSLGQLHLIGRkGLDQDYYKALHYFLKAAKA 246
Cdd:COG0790   202 --------AEQGDADAQYNLGRLYLNGE-GVEKDLEKALRWLRKAAEQ 240
TPR COG0790
TPR repeat [General function prediction only];
413-535 1.68e-12

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 67.65  E-value: 1.68e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462499489 413 SLVQYALLAEMGYEVAQSNSAFILESKKANILEKEKMYPMALLLWNRAAIQGNAFARVKIGDYHYYGYGTKKDYQTAATH 492
Cdd:COG0790    10 AAAAAAAALAAAAAAAGAAAAAAAAAAAAAALAAAAGAAAAAAAAAAAAAAGGAEAQYNLGLMYAEGRGVPKDYEKALEW 89

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 2462499489 493 YSIAANKyHNAQAMFNLAYMYEHGLGITKDIHLARRLYDMAAQ 535
Cdd:COG0790    90 FEKAAEQ-GDAEAQYNLGLMYEEGLGVPQDYAKALEWYEKAAE 131
SEL1 smart00671
Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.
 503-535 3.26e-06

Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.


Pssm-ID: 214772 [Multi-domain]  Cd Length: 36  Bit Score: 44.09  E-value: 3.26e-06
                           10        20        30
                   ....*....|....*....|....*....|...
gi 2462499489  503 AQAMFNLAYMYEHGLGITKDIHLARRLYDMAAQ 535
Cdd:smart00671   1 AEAQYNLGQMYEYGLGVPKDLEKALEYYKKAAE 33
Sel1 pfam08238
Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.
 503-535 3.65e-06

Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.


Pssm-ID: 429881 [Multi-domain]  Cd Length: 35  Bit Score: 43.66  E-value: 3.65e-06
                          10        20        30
                  ....*....|....*....|....*....|...
gi 2462499489 503 AQAMFNLAYMYEHGLGITKDIHLARRLYDMAAQ 535
Cdd:pfam08238   1 AEAQYRLGYLYLYGLGVPKDPEKALEWYEKAAE 33
SEL1 smart00671
Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.
 322-356 4.73e-06

Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.


Pssm-ID: 214772 [Multi-domain]  Cd Length: 36  Bit Score: 43.32  E-value: 4.73e-06
                           10        20        30
                   ....*....|....*....|....*....|....*
gi 2462499489  322 PDAQFQLGFMYYSGSGIWKDYKLAFKYFYLASQSG 356
Cdd:smart00671   1 AEAQYNLGQMYEYGLGVPKDLEKALEYYKKAAELG 35
SEL1 smart00671
Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.
 286-320 7.14e-06

Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.


Pssm-ID: 214772 [Multi-domain]  Cd Length: 36  Bit Score: 42.93  E-value: 7.14e-06
                           10        20        30
                   ....*....|....*....|....*....|....*
gi 2462499489  286 AIGLHGLGLLYFHGKGVPLNYAEALKYFQKAAEKG 320
Cdd:smart00671   1 AEAQYNLGQMYEYGLGVPKDLEKALEYYKKAAELG 35
Sel1 pfam08238
Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.
 286-320 1.56e-05

Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.


Pssm-ID: 429881 [Multi-domain]  Cd Length: 35  Bit Score: 42.12  E-value: 1.56e-05
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 2462499489 286 AIGLHGLGLLYFHGKGVPLNYAEALKYFQKAAEKG 320
Cdd:pfam08238   1 AEAQYRLGYLYLYGLGVPKDPEKALEWYEKAAELG 35
TPR COG0790
TPR repeat [General function prediction only];
446-535 1.04e-04

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 44.15  E-value: 1.04e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462499489 446 KEKMYPMALLLWNRAAIQGNAFARVKIGDYHYYGYGTKKDYQTAATHYSIAANKYHNAQAMFNLAYMYEHGLGITKDIHL 525
Cdd:COG0790     6 AAAAAAAAAAAALAAAAAAAGAAAAAAAAAAAAAALAAAAGAAAAAAAAAAAAAAGGAEAQYNLGLMYAEGRGVPKDYEK 85

                          90
                  ....*....|
gi 2462499489 526 ARRLYDMAAQ 535
Cdd:COG0790    86 ALEWFEKAAE 95
SEL1 smart00671
Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.
 358-393 1.94e-04

Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.


Pssm-ID: 214772 [Multi-domain]  Cd Length: 36  Bit Score: 39.08  E-value: 1.94e-04
                           10        20        30
                   ....*....|....*....|....*....|....*.
gi 2462499489  358 PLAIYYLAKMYATGTGVVRSCRTAVELYKGVCELGH 393
Cdd:smart00671   1 AEAQYNLGQMYEYGLGVPKDLEKALEYYKKAAELGN 36
Sel1 pfam08238
Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.
 322-356 3.84e-04

Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.


Pssm-ID: 429881 [Multi-domain]  Cd Length: 35  Bit Score: 37.89  E-value: 3.84e-04
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 2462499489 322 PDAQFQLGFMYYSGSGIWKDYKLAFKYFYLASQSG 356
Cdd:pfam08238   1 AEAQYRLGYLYLYGLGVPKDPEKALEWYEKAAELG 35
SEL1 smart00671
Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.
 249-285 5.39e-03

Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.


Pssm-ID: 214772 [Multi-domain]  Cd Length: 36  Bit Score: 34.84  E-value: 5.39e-03
                           10        20        30
                   ....*....|....*....|....*....|....*..
gi 2462499489  249 ANAMAFIGKMYLEGNAaVPQNNATAFKYFSMAASKGN 285
Cdd:smart00671   1 AEAQYNLGQMYEYGLG-VPKDLEKALEYYKKAAELGN 36
SEL1 smart00671
Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.
 466-501 6.96e-03

Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.


Pssm-ID: 214772 [Multi-domain]  Cd Length: 36  Bit Score: 34.46  E-value: 6.96e-03
                           10        20        30
                   ....*....|....*....|....*....|....*.
gi 2462499489  466 AFARVKIGDYHYYGYGTKKDYQTAATHYSIAANKYH 501
Cdd:smart00671   1 AEAQYNLGQMYEYGLGVPKDLEKALEYYKKAAELGN 36
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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