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Conserved domains on  [gi|2462581676|ref|XP_054180050|]
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protein sel-1 homolog 2 isoform X10 [Homo sapiens]

Protein Classification

tetratricopeptide repeat protein( domain architecture ID 11434433)

tetratricopeptide repeat (TPR) protein may adopt a right-handed helical structure with an amphipathic channel and may function as an interaction scaffold in the formation of multi-protein complexes

CATH:  1.25.40.10
Gene Ontology:  GO:0005515
PubMed:  10517866|30708253
SCOP:  3001345

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TPR COG0790
TPR repeat [General function prediction only];
300-449 1.24e-44

TPR repeat [General function prediction only];


:

Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 158.17  E-value: 1.24e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462581676 300 QKALHYFLKAAKAGSANAMAFIGKMYLEGNAaVPQNNATAFKYFSMAASKGNAIGLHGLGLLYFHGKGVPLNYAEALKYF 379
Cdd:COG0790    84 EKALEWFEKAAEQGDAEAQYNLGLMYEEGLG-VPQDYAKALEWYEKAAEQGDADAQYNLGLLYLNGEGVPKDPAKAAEWY 162

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462581676 380 QKAAEKGWPDAQFQLGFMYYSGSGIWKDYKLAFKYFYLASQSGQPLAIYYLAKMYATGTGVVRSCRTAVE 449
Cdd:COG0790   163 RKAAEQGDADAQYNLGVLYENGRGVPKDPAKALEWYRKAAEQGDADAQYNLGRLYLNGEGVEKDLEKALR 232
TPR COG0790
TPR repeat [General function prediction only];
124-247 2.38e-18

TPR repeat [General function prediction only];


:

Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 84.59  E-value: 2.38e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462581676 124 QKQKEEAYLLFAKAADMGNLKAMEKMADALLFGNFGVQNITAAIQLYESLAKEGSCKAQNALGFLSSYGIGMEYDQAKAL 203
Cdd:COG0790   116 PQDYAKALEWYEKAAEQGDADAQYNLGLLYLNGEGVPKDPAKAAEWYRKAAEQGDADAQYNLGVLYENGRGVPKDPAKAL 195

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 2462581676 204 IYYTFGSAGGNMMSQMILGYRYLSGINVLQNCEVALSYYKKVAD 247
Cdd:COG0790   196 EWYRKAAEQGDADAQYNLGRLYLNGEGVEKDLEKALRWLRKAAE 239
Mplasa_alph_rch super family cl37461
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 18-128 1.43e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


The actual alignment was detected with superfamily member TIGR04523:

Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 44.63  E-value: 1.43e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462581676  18 IKTIKAEEHNKRQKERNVTTQVS-----VNEIKQYLSHILEQRTSSNV--------INKRENLLEKKKNQRKIRIKGIQN 84
Cdd:TIGR04523 309 NKELKSELKNQEKKLEEIQNQISqnnkiISQLNEQISQLKKELTNSESensekqreLEEKQNEIEKLKKENQSYKQEIKN 388

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 2462581676  85 kdiLKRNKNHLQKQAEKNftDEGDQLFKMGIKVLQQSKSQKQKE 128
Cdd:TIGR04523 389 ---LESQINDLESKIQNQ--EKLNQQKDEQIKKLQQEKELLEKE 427
 
Name Accession Description Interval E-value
TPR COG0790
TPR repeat [General function prediction only];
300-449 1.24e-44

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 158.17  E-value: 1.24e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462581676 300 QKALHYFLKAAKAGSANAMAFIGKMYLEGNAaVPQNNATAFKYFSMAASKGNAIGLHGLGLLYFHGKGVPLNYAEALKYF 379
Cdd:COG0790    84 EKALEWFEKAAEQGDAEAQYNLGLMYEEGLG-VPQDYAKALEWYEKAAEQGDADAQYNLGLLYLNGEGVPKDPAKAAEWY 162

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462581676 380 QKAAEKGWPDAQFQLGFMYYSGSGIWKDYKLAFKYFYLASQSGQPLAIYYLAKMYATGTGVVRSCRTAVE 449
Cdd:COG0790   163 RKAAEQGDADAQYNLGVLYENGRGVPKDPAKALEWYRKAAEQGDADAQYNLGRLYLNGEGVEKDLEKALR 232
TPR COG0790
TPR repeat [General function prediction only];
124-247 2.38e-18

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 84.59  E-value: 2.38e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462581676 124 QKQKEEAYLLFAKAADMGNLKAMEKMADALLFGNFGVQNITAAIQLYESLAKEGSCKAQNALGFLSSYGIGMEYDQAKAL 203
Cdd:COG0790   116 PQDYAKALEWYEKAAEQGDADAQYNLGLLYLNGEGVPKDPAKAAEWYRKAAEQGDADAQYNLGVLYENGRGVPKDPAKAL 195

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 2462581676 204 IYYTFGSAGGNMMSQMILGYRYLSGINVLQNCEVALSYYKKVAD 247
Cdd:COG0790   196 EWYRKAAEQGDADAQYNLGRLYLNGEGVEKDLEKALRWLRKAAE 239
SEL1 smart00671
Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.
 388-422 5.15e-07

Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.


Pssm-ID: 214772 [Multi-domain]  Cd Length: 36  Bit Score: 46.01  E-value: 5.15e-07
                           10        20        30
                   ....*....|....*....|....*....|....*
gi 2462581676  388 PDAQFQLGFMYYSGSGIWKDYKLAFKYFYLASQSG 422
Cdd:smart00671   1 AEAQYNLGQMYEYGLGVPKDLEKALEYYKKAAELG 35
Sel1 pfam08238
Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.
 352-386 1.80e-06

Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.


Pssm-ID: 429881 [Multi-domain]  Cd Length: 35  Bit Score: 44.43  E-value: 1.80e-06
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 2462581676 352 AIGLHGLGLLYFHGKGVPLNYAEALKYFQKAAEKG 386
Cdd:pfam08238   1 AEAQYRLGYLYLYGLGVPKDPEKALEWYEKAAELG 35
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 18-128 1.43e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 44.63  E-value: 1.43e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462581676  18 IKTIKAEEHNKRQKERNVTTQVS-----VNEIKQYLSHILEQRTSSNV--------INKRENLLEKKKNQRKIRIKGIQN 84
Cdd:TIGR04523 309 NKELKSELKNQEKKLEEIQNQISqnnkiISQLNEQISQLKKELTNSESensekqreLEEKQNEIEKLKKENQSYKQEIKN 388

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 2462581676  85 kdiLKRNKNHLQKQAEKNftDEGDQLFKMGIKVLQQSKSQKQKE 128
Cdd:TIGR04523 389 ---LESQINDLESKIQNQ--EKLNQQKDEQIKKLQQEKELLEKE 427
SEL1 smart00671
Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.
 216-247 2.73e-03

Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.


Pssm-ID: 214772 [Multi-domain]  Cd Length: 36  Bit Score: 35.61  E-value: 2.73e-03
                           10        20        30
                   ....*....|....*....|....*....|..
gi 2462581676  216 MSQMILGYRYLSGINVLQNCEVALSYYKKVAD 247
Cdd:smart00671   2 EAQYNLGQMYEYGLGVPKDLEKALEYYKKAAE 33
 
Name Accession Description Interval E-value
TPR COG0790
TPR repeat [General function prediction only];
300-449 1.24e-44

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 158.17  E-value: 1.24e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462581676 300 QKALHYFLKAAKAGSANAMAFIGKMYLEGNAaVPQNNATAFKYFSMAASKGNAIGLHGLGLLYFHGKGVPLNYAEALKYF 379
Cdd:COG0790    84 EKALEWFEKAAEQGDAEAQYNLGLMYEEGLG-VPQDYAKALEWYEKAAEQGDADAQYNLGLLYLNGEGVPKDPAKAAEWY 162

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462581676 380 QKAAEKGWPDAQFQLGFMYYSGSGIWKDYKLAFKYFYLASQSGQPLAIYYLAKMYATGTGVVRSCRTAVE 449
Cdd:COG0790   163 RKAAEQGDADAQYNLGVLYENGRGVPKDPAKALEWYRKAAEQGDADAQYNLGRLYLNGEGVEKDLEKALR 232
TPR COG0790
TPR repeat [General function prediction only];
282-449 1.09e-39

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 144.69  E-value: 1.09e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462581676 282 WDIYQYYKFLAERGDVQIQKALHYFLKAAKAGSANAMAFIGKMYLEGNAaVPQNNATAFKYFSMAASKGNAIGLHGLGLL 361
Cdd:COG0790    30 AAAAAAAAAAALAAAAGAAAAAAAAAAAAAAGGAEAQYNLGLMYAEGRG-VPKDYEKALEWFEKAAEQGDAEAQYNLGLM 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462581676 362 YFHGKGVPLNYAEALKYFQKAAEKGWPDAQFQLGFMYYSGSGIWKDYKLAFKYFYLASQSGQPLAIYYLAKMYATGTGVV 441
Cdd:COG0790   109 YEEGLGVPQDYAKALEWYEKAAEQGDADAQYNLGLLYLNGEGVPKDPAKAAEWYRKAAEQGDADAQYNLGVLYENGRGVP 188


                  ....*...
gi 2462581676 442 RSCRTAVE 449
Cdd:COG0790   189 KDPAKALE 196
TPR COG0790
TPR repeat [General function prediction only];
126-418 2.34e-37

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 138.14  E-value: 2.34e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462581676 126 QKEEAYLLFAKAADMGNLKAMEKMADALLFGnfGVQNITAAIQLYESLAKEGSCKAQNALGFLSSYGIGMEYDQAKALIY 205
Cdd:COG0790    12 AAAAAALAAAAAAAGAAAAAAAAAAAAAALA--AAAGAAAAAAAAAAAAAAGGAEAQYNLGLMYAEGRGVPKDYEKALEW 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462581676 206 YTFGSAGGNMMSQMILGYRYLSGINVLQNcevalsyykkvadyiadtfeksegvpvekvrlterpenlssnseildwdiy 285
Cdd:COG0790    90 FEKAAEQGDAEAQYNLGLMYEEGLGVPQD--------------------------------------------------- 118

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462581676 286 qyykflaergdvqIQKALHYFLKAAKAGSANAMAFIGKMYLEGNaAVPQNNATAFKYFSMAASKGNAIGLHGLGLLYFHG 365
Cdd:COG0790   119 -------------YAKALEWYEKAAEQGDADAQYNLGLLYLNGE-GVPKDPAKAAEWYRKAAEQGDADAQYNLGVLYENG 184

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2462581676 366 KGVPLNYAEALKYFQKAAEKGWPDAQFQLGFMYYSGSGIWKDYKLAFKYFYLA 418
Cdd:COG0790   185 RGVPKDPAKALEWYRKAAEQGDADAQYNLGRLYLNGEGVEKDLEKALRWLRKA 237
TPR COG0790
TPR repeat [General function prediction only];
307-488 6.53e-28

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 111.94  E-value: 6.53e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462581676 307 LKAAKAGSANAMAFIGKMYLEGNAAVPQNNATAFKYFSMAASKGNAIGLHGLGLLYFHGKGVPLNYAEALKYFQKAAEKG 386
Cdd:COG0790    18 LAAAAAAAGAAAAAAAAAAAAAALAAAAGAAAAAAAAAAAAAAGGAEAQYNLGLMYAEGRGVPKDYEKALEWFEKAAEQG 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462581676 387 WPDAQFQLGFMYYSGSGIWKDYKLAFKYFYLASQSGQPLAIYYLAKMYATGTGVVRSCRTAVEkrltFLKK--------- 457
Cdd:COG0790    98 DAEAQYNLGLMYEEGLGVPQDYAKALEWYEKAAEQGDADAQYNLGLLYLNGEGVPKDPAKAAE----WYRKaaeqgdada 173

                         170       180       190
                  ....*....|....*....|....*....|.
gi 2462581676 458 RRCIQWRFSYGIELPfKDIHLARRLYDMAAQ 488
Cdd:COG0790   174 QYNLGVLYENGRGVP-KDPAKALEWYRKAAE 203
TPR COG0790
TPR repeat [General function prediction only];
124-247 2.38e-18

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 84.59  E-value: 2.38e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462581676 124 QKQKEEAYLLFAKAADMGNLKAMEKMADALLFGNFGVQNITAAIQLYESLAKEGSCKAQNALGFLSSYGIGMEYDQAKAL 203
Cdd:COG0790   116 PQDYAKALEWYEKAAEQGDADAQYNLGLLYLNGEGVPKDPAKAAEWYRKAAEQGDADAQYNLGVLYENGRGVPKDPAKAL 195

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 2462581676 204 IYYTFGSAGGNMMSQMILGYRYLSGINVLQNCEVALSYYKKVAD 247
Cdd:COG0790   196 EWYRKAAEQGDADAQYNLGRLYLNGEGVEKDLEKALRWLRKAAE 239
TPR COG0790
TPR repeat [General function prediction only];
326-449 1.36e-14

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 73.42  E-value: 1.36e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462581676 326 LEGNAAVPQNNATAFKYFSMAASKGNAIGLHGLGLLYFHGKGVPLNYAEALKYFQKAAEKGWPDAQFQLGFMYYSGSGIW 405
Cdd:COG0790     1 LALAAAAAAAAAAAAAALAAAAAAAGAAAAAAAAAAAAAALAAAAGAAAAAAAAAAAAAAGGAEAQYNLGLMYAEGRGVP 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 2462581676 406 KDYKLAFKYFYLASQSGQPLAIYYLAKMYATGTGVVRSCRTAVE 449
Cdd:COG0790    81 KDYEKALEWFEKAAEQGDAEAQYNLGLMYEEGLGVPQDYAKALE 124
SEL1 smart00671
Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.
 388-422 5.15e-07

Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.


Pssm-ID: 214772 [Multi-domain]  Cd Length: 36  Bit Score: 46.01  E-value: 5.15e-07
                           10        20        30
                   ....*....|....*....|....*....|....*
gi 2462581676  388 PDAQFQLGFMYYSGSGIWKDYKLAFKYFYLASQSG 422
Cdd:smart00671   1 AEAQYNLGQMYEYGLGVPKDLEKALEYYKKAAELG 35
SEL1 smart00671
Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.
 352-386 8.17e-07

Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.


Pssm-ID: 214772 [Multi-domain]  Cd Length: 36  Bit Score: 45.63  E-value: 8.17e-07
                           10        20        30
                   ....*....|....*....|....*....|....*
gi 2462581676  352 AIGLHGLGLLYFHGKGVPLNYAEALKYFQKAAEKG 386
Cdd:smart00671   1 AEAQYNLGQMYEYGLGVPKDLEKALEYYKKAAELG 35
Sel1 pfam08238
Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.
 352-386 1.80e-06

Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.


Pssm-ID: 429881 [Multi-domain]  Cd Length: 35  Bit Score: 44.43  E-value: 1.80e-06
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 2462581676 352 AIGLHGLGLLYFHGKGVPLNYAEALKYFQKAAEKG 386
Cdd:pfam08238   1 AEAQYRLGYLYLYGLGVPKDPEKALEWYEKAAELG 35
Sel1 pfam08238
Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.
 388-422 5.47e-05

Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.


Pssm-ID: 429881 [Multi-domain]  Cd Length: 35  Bit Score: 40.20  E-value: 5.47e-05
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 2462581676 388 PDAQFQLGFMYYSGSGIWKDYKLAFKYFYLASQSG 422
Cdd:pfam08238   1 AEAQYRLGYLYLYGLGVPKDPEKALEWYEKAAELG 35
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 18-128 1.43e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 44.63  E-value: 1.43e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462581676  18 IKTIKAEEHNKRQKERNVTTQVS-----VNEIKQYLSHILEQRTSSNV--------INKRENLLEKKKNQRKIRIKGIQN 84
Cdd:TIGR04523 309 NKELKSELKNQEKKLEEIQNQISqnnkiISQLNEQISQLKKELTNSESensekqreLEEKQNEIEKLKKENQSYKQEIKN 388

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 2462581676  85 kdiLKRNKNHLQKQAEKNftDEGDQLFKMGIKVLQQSKSQKQKE 128
Cdd:TIGR04523 389 ---LESQINDLESKIQNQ--EKLNQQKDEQIKKLQQEKELLEKE 427
SEL1 smart00671
Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.
 315-351 7.73e-04

Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.


Pssm-ID: 214772 [Multi-domain]  Cd Length: 36  Bit Score: 37.15  E-value: 7.73e-04
                           10        20        30
                   ....*....|....*....|....*....|....*..
gi 2462581676  315 ANAMAFIGKMYLEGNAaVPQNNATAFKYFSMAASKGN 351
Cdd:smart00671   1 AEAQYNLGQMYEYGLG-VPKDLEKALEYYKKAAELGN 36
SEL1 smart00671
Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.
 216-247 2.73e-03

Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.


Pssm-ID: 214772 [Multi-domain]  Cd Length: 36  Bit Score: 35.61  E-value: 2.73e-03
                           10        20        30
                   ....*....|....*....|....*....|..
gi 2462581676  216 MSQMILGYRYLSGINVLQNCEVALSYYKKVAD 247
Cdd:smart00671   2 EAQYNLGQMYEYGLGVPKDLEKALEYYKKAAE 33
Sel1 pfam08238
Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.
 315-350 3.37e-03

Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.


Pssm-ID: 429881 [Multi-domain]  Cd Length: 35  Bit Score: 35.19  E-value: 3.37e-03
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 2462581676 315 ANAMAFIGKMYLEGnAAVPQNNATAFKYFSMAASKG 350
Cdd:pfam08238   1 AEAQYRLGYLYLYG-LGVPKDPEKALEWYEKAAELG 35
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
298-435 8.99e-03

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 38.06  E-value: 8.99e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462581676 298 QIQKALHYFLKAAK--AGSANAMAFIGKMYLEGNaavpqNNATAFKYFSMAASK--GNAIGLHGLGLLYFHGKgvplNYA 373
Cdd:COG0457    23 RYEEAIEDYEKALEldPDDAEALYNLGLAYLRLG-----RYEEALADYEQALELdpDDAEALNNLGLALQALG----RYE 93

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2462581676 374 EALKYFQKAAEK--GWPDAQFQLGFMYYSgsgiWKDYKLAFKYF--YLASQSGQPLAIYYLAKMYA 435
Cdd:COG0457    94 EALEDYDKALELdpDDAEALYNLGLALLE----LGRYDEAIEAYerALELDPDDADALYNLGIALE 155
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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