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Conserved domains on  [gi|2217264602|ref|XP_047303931|]
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tetratricopeptide repeat protein 24 isoform X7 [Homo sapiens]

Protein Classification

tetratricopeptide repeat protein( domain architecture ID 11929115)

tetratricopeptide repeat (TPR) protein may adopt a right-handed helical structure with an amphipathic channel and may function as an interaction scaffold in the formation of multi-protein complexes

CATH:  1.25.40.10
Gene Ontology:  GO:0005515
PubMed:  30708253|10517866
SCOP:  3001345

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
121-408 8.66e-12

Tetratricopeptide (TPR) repeat [General function prediction only];


:

Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 65.03  E-value: 8.66e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217264602 121 FNVALAYHALGELPQALAWYHRALGHYQpqgDQGEAWAKMGACYQALGQPELAAHCLQEAsqayaqerqlraaalalgaa 200
Cdd:COG0457    12 NNLGLAYRRLGRYEEAIEDYEKALELDP---DDAEALYNLGLAYLRLGRYEEALADYEQA-------------------- 68

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217264602 201 agcmlksgrhrvgevvqvLEKSRRLAErsterrllghLYNDLGLGYSQLQLFPLAVEAFLQALPLcwvPGEQATVLRNLG 280
Cdd:COG0457    69 ------------------LELDPDDAE----------ALNNLGLALQALGRYEEALEDYDKALEL---DPDDAEALYNLG 117

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217264602 281 MAHNALGNYQEAREFHQKAADLHGSVGQRWEqgrsfgSLAFALSQLGDHKAARDNYLHALQAARDsgDMKGQWQACEGLG 360
Cdd:COG0457   118 LALLELGRYDEAIEAYERALELDPDDADALY------NLGIALEKLGRYEEALELLEKLEAAALA--ALLAAALGEAALA 189

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*...
gi 2217264602 361 AAAARLGQYDQALKYYKEALAQCQKEPDSVRERLVAKLADTVRTRLAQ 408
Cdd:COG0457   190 LAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALALLLALRLAA 237
Spy super family cl27809
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 29-182 4.02e-10

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


The actual alignment was detected with superfamily member COG3914:

Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 61.93  E-value: 4.02e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217264602  29 WLRQEASIQALTRAGHGALQAGQNHEALNNFQRAFLLASKAPQTRdtpvlqacaFNLGAAYVETGDPARGLELLLRAHpe 108
Cdd:COG3914    71 AAALLLLAALLELAALLLQALGRYEEALALYRRALALNPDNAEAL---------FNLGNLLLALGRLEEALAALRRAL-- 139

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2217264602 109 ekAQGRRHGDQCFNVALAYHALGELPQALAWYHRALghyQPQGDQGEAWAKMGACYQALGQPELAAHCLQEASQ 182
Cdd:COG3914   140 --ALNPDFAEAYLNLGEALRRLGRLEEAIAALRRAL---ELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALE 208
 
Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
121-408 8.66e-12

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 65.03  E-value: 8.66e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217264602 121 FNVALAYHALGELPQALAWYHRALGHYQpqgDQGEAWAKMGACYQALGQPELAAHCLQEAsqayaqerqlraaalalgaa 200
Cdd:COG0457    12 NNLGLAYRRLGRYEEAIEDYEKALELDP---DDAEALYNLGLAYLRLGRYEEALADYEQA-------------------- 68

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217264602 201 agcmlksgrhrvgevvqvLEKSRRLAErsterrllghLYNDLGLGYSQLQLFPLAVEAFLQALPLcwvPGEQATVLRNLG 280
Cdd:COG0457    69 ------------------LELDPDDAE----------ALNNLGLALQALGRYEEALEDYDKALEL---DPDDAEALYNLG 117

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217264602 281 MAHNALGNYQEAREFHQKAADLHGSVGQRWEqgrsfgSLAFALSQLGDHKAARDNYLHALQAARDsgDMKGQWQACEGLG 360
Cdd:COG0457   118 LALLELGRYDEAIEAYERALELDPDDADALY------NLGIALEKLGRYEEALELLEKLEAAALA--ALLAAALGEAALA 189

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*...
gi 2217264602 361 AAAARLGQYDQALKYYKEALAQCQKEPDSVRERLVAKLADTVRTRLAQ 408
Cdd:COG0457   190 LAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALALLLALRLAA 237
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 29-182 4.02e-10

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 61.93  E-value: 4.02e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217264602  29 WLRQEASIQALTRAGHGALQAGQNHEALNNFQRAFLLASKAPQTRdtpvlqacaFNLGAAYVETGDPARGLELLLRAHpe 108
Cdd:COG3914    71 AAALLLLAALLELAALLLQALGRYEEALALYRRALALNPDNAEAL---------FNLGNLLLALGRLEEALAALRRAL-- 139

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2217264602 109 ekAQGRRHGDQCFNVALAYHALGELPQALAWYHRALghyQPQGDQGEAWAKMGACYQALGQPELAAHCLQEASQ 182
Cdd:COG3914   140 --ALNPDFAEAYLNLGEALRRLGRLEEAIAALRRAL---ELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALE 208
TPR_12 pfam13424
Tetratricopeptide repeat;
271-345 8.31e-08

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 49.31  E-value: 8.31e-08
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2217264602 271 EQATVLRNLGMAHNALGNYQEAREFHQKAADLHGSV--GQRWEQGRSFGSLAFALSQLGDHKAARDNYLHALQAARD 345
Cdd:pfam13424   1 DVATALNNLAAVLRRLGRYDEALELLEKALEIARRLlgPDHPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 353-381 2.93e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 35.11  E-value: 2.93e-03
                           10        20
                   ....*....|....*....|....*....
gi 2217264602  353 WQACEGLGAAAARLGQYDQALKYYKEALA 381
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALE 29
 
Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
121-408 8.66e-12

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 65.03  E-value: 8.66e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217264602 121 FNVALAYHALGELPQALAWYHRALGHYQpqgDQGEAWAKMGACYQALGQPELAAHCLQEAsqayaqerqlraaalalgaa 200
Cdd:COG0457    12 NNLGLAYRRLGRYEEAIEDYEKALELDP---DDAEALYNLGLAYLRLGRYEEALADYEQA-------------------- 68

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217264602 201 agcmlksgrhrvgevvqvLEKSRRLAErsterrllghLYNDLGLGYSQLQLFPLAVEAFLQALPLcwvPGEQATVLRNLG 280
Cdd:COG0457    69 ------------------LELDPDDAE----------ALNNLGLALQALGRYEEALEDYDKALEL---DPDDAEALYNLG 117

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217264602 281 MAHNALGNYQEAREFHQKAADLHGSVGQRWEqgrsfgSLAFALSQLGDHKAARDNYLHALQAARDsgDMKGQWQACEGLG 360
Cdd:COG0457   118 LALLELGRYDEAIEAYERALELDPDDADALY------NLGIALEKLGRYEEALELLEKLEAAALA--ALLAAALGEAALA 189

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*...
gi 2217264602 361 AAAARLGQYDQALKYYKEALAQCQKEPDSVRERLVAKLADTVRTRLAQ 408
Cdd:COG0457   190 LAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALALLLALRLAA 237
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 157-382 3.97e-11

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 63.59  E-value: 3.97e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217264602 157 WAKMGACYQALGQPELAAHCLQEASQAYAQERQLRAaalalgaaagcMLKSGRHRVGEVVQVLEKSRRLAERSTERrllG 236
Cdd:COG2956    11 WYFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHL-----------ALGNLYRRRGEYDRAIRIHQKLLERDPDR---A 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217264602 237 HLYNDLGLGYSQLQLFPLAVEAFLQALPLcwvPGEQATVLRNLGMAHNALGNYQEAREFHQKAADLHGSVGQRWEQgrsf 316
Cdd:COG2956    77 EALLELAQDYLKAGLLDRAEELLEKLLEL---DPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCE---- 149

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2217264602 317 gsLAFALSQLGDHKAARDNYLHALQAARDSGDmkgqwqACEGLGAAAARLGQYDQALKYYKEALAQ 382
Cdd:COG2956   150 --LAELYLEQGDYDEAIEALEKALKLDPDCAR------ALLLLAELYLEQGDYEEAIAALERALEQ 207
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 42-342 3.34e-10

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 60.90  E-value: 3.34e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217264602  42 AGHGALQAGQNHEALNNFQRAFLLASKA----PQTRDTpvlqacAFNLGAAYVETGDPARGLELLLRAHpeekAQGRRHG 117
Cdd:COG2956     7 AALGWYFKGLNYLLNGQPDKAIDLLEEAleldPETVEA------HLALGNLYRRRGEYDRAIRIHQKLL----ERDPDRA 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217264602 118 DQCFNVALAYHALGELPQALAWYHRALghyQPQGDQGEAWAKMGACYQALGQPELAAHCLQEASQAYAQERQLRAAALAl 197
Cdd:COG2956    77 EALLELAQDYLKAGLLDRAEELLEKLL---ELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAE- 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217264602 198 gaaagcmLKSGRHRVGEVVQVLEKSRRLAERSTE-RRLLGHLYNDLGlgysqlqLFPLAVEAFLQALPLCwvpGEQATVL 276
Cdd:COG2956   153 -------LYLEQGDYDEAIEALEKALKLDPDCARaLLLLAELYLEQG-------DYEEAIAALERALEQD---PDYLPAL 215

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2217264602 277 RNLGMAHNALGNYQEAREFHQKAADLHGSVGQRWEqgrsfgsLAFALSQLGDHKAARDNYLHALQA 342
Cdd:COG2956   216 PRLAELYEKLGDPEEALELLRKALELDPSDDLLLA-------LADLLERKEGLEAALALLERQLRR 274
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 29-182 4.02e-10

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 61.93  E-value: 4.02e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217264602  29 WLRQEASIQALTRAGHGALQAGQNHEALNNFQRAFLLASKAPQTRdtpvlqacaFNLGAAYVETGDPARGLELLLRAHpe 108
Cdd:COG3914    71 AAALLLLAALLELAALLLQALGRYEEALALYRRALALNPDNAEAL---------FNLGNLLLALGRLEEALAALRRAL-- 139

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2217264602 109 ekAQGRRHGDQCFNVALAYHALGELPQALAWYHRALghyQPQGDQGEAWAKMGACYQALGQPELAAHCLQEASQ 182
Cdd:COG3914   140 --ALNPDFAEAYLNLGEALRRLGRLEEAIAALRRAL---ELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALE 208
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 125-353 5.18e-10

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 61.93  E-value: 5.18e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217264602 125 LAYHALGELPQALAWYHRALGHYQPQGDQGEAWAKMGACYQALGQPELAAHCLQEASQAYAQERQLRAAALALGAAAGCM 204
Cdd:COG3914     1 AAAAALLALAALAAAALLAAAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAAL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217264602 205 LKS------GRHRVGEVVQVLEKSRRLAERSTErrllghLYNDLGLGYSQLQLFPLAVEAFLQALPLcwvPGEQATVLRN 278
Cdd:COG3914    81 LELaalllqALGRYEEALALYRRALALNPDNAE------ALFNLGNLLLALGRLEEALAALRRALAL---NPDFAEAYLN 151

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2217264602 279 LGMAHNALGNYQEAREFHQKAADLHGsvgqrwEQGRSFGSLAFALSQLGDHKAARDNYLHALQAARDSGDMKGQW 353
Cdd:COG3914   152 LGEALRRLGRLEEAIAALRRALELDP------DNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNL 220
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 155-381 5.18e-10

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 61.93  E-value: 5.18e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217264602 155 EAWAKMGACYQALGQPELAAHCLQEASQAYAQERQLRAAALALGAaagcmLKSGRHRVGEVVQVLEKSRRLAERSTERRL 234
Cdd:COG3914     2 AAAALLALAALAAAALLAAAAAAELALAAELEAAALAAALGLALL-----LLAALAEAAAAALLALAAGEAAAAAAALLL 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217264602 235 LGHLYNDLGLGYSQLQLFPLAVEAFLQALPLCwvpGEQATVLRNLGMAHNALGNYQEAREFHQKAADLHGsvgqrwEQGR 314
Cdd:COG3914    77 LAALLELAALLLQALGRYEEALALYRRALALN---PDNAEALFNLGNLLLALGRLEEALAALRRALALNP------DFAE 147

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2217264602 315 SFGSLAFALSQLGDHKAARDNYLHALQAARDsgdmkgQWQACEGLGAAAARLGQYDQALKYYKEALA 381
Cdd:COG3914   148 AYLNLGEALRRLGRLEEAIAALRRALELDPD------NAEALNNLGNALQDLGRLEEAIAAYRRALE 208
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 41-328 7.74e-10

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 61.16  E-value: 7.74e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217264602  41 RAGHGALQAGQNHEALNNFQRAFLLASKAPQTRDTPVLQACAFNLGAAYVETGDPARGLELLLRAHPEEKAQGRRHGDQC 120
Cdd:COG3914     2 AAAALLALAALAAAALLAAAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALL 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217264602 121 FNVALAYHALGELPQALAWYHRALGHyqpQGDQGEAWAKMGACYQALGQPELAAHCLQEAsqayaqerqlraaalalgaa 200
Cdd:COG3914    82 ELAALLLQALGRYEEALALYRRALAL---NPDNAEALFNLGNLLLALGRLEEALAALRRA-------------------- 138

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217264602 201 agcmlksgrhrvgevvqvLEKSRRLAErsterrllghLYNDLGLGYSQLQLFPLAVEAFLQALPLCwvpGEQATVLRNLG 280
Cdd:COG3914   139 ------------------LALNPDFAE----------AYLNLGEALRRLGRLEEAIAALRRALELD---PDNAEALNNLG 187

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*...
gi 2217264602 281 MAHNALGNYQEAREFHQKAADLHGsvgqrwEQGRSFGSLAFALSQLGD 328
Cdd:COG3914   188 NALQDLGRLEEAIAAYRRALELDP------DNADAHSNLLFALRQACD 229
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
83-373 1.34e-09

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 58.48  E-value: 1.34e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217264602  83 FNLGAAYVETGDPARGLELLLRAHpeekAQGRRHGDQCFNVALAYHALGELPQALAWYHRALghyQPQGDQGEAWAKMGA 162
Cdd:COG0457    12 NNLGLAYRRLGRYEEAIEDYEKAL----ELDPDDAEALYNLGLAYLRLGRYEEALADYEQAL---ELDPDDAEALNNLGL 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217264602 163 CYQALGQPELAAHCLQEAsqayaqerqlraaalalgaaagcmlksgrhrvgevvqvLEKSRRLAErsterrllghLYNDL 242
Cdd:COG0457    85 ALQALGRYEEALEDYDKA--------------------------------------LELDPDDAE----------ALYNL 116

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217264602 243 GLGYSQLQLFPLAVEAFLQALPLCWvpgEQATVLRNLGMAHNALGNYQEAREFHQKAADLHGSVGQRWEQGRSFGSLAFA 322
Cdd:COG0457   117 GLALLELGRYDEAIEAYERALELDP---DDADALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAA 193

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2217264602 323 LSQLGDHKAARDNYLHALQAARDSGDMKGQWQACEGLGAAAARLGQYDQAL 373
Cdd:COG0457   194 EVLLALLLALEQALRKKLAILTLAALAELLLLALALLLALRLAALALYQYR 244
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
152-411 1.80e-09

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 58.09  E-value: 1.80e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217264602 152 DQGEAWAKMGACYQALGQPELAAHCLQEAsqayaqerqlraaalalgaaagcmlksgrhrvgevvqvLEKSRRLAErste 231
Cdd:COG0457     6 DDAEAYNNLGLAYRRLGRYEEAIEDYEKA--------------------------------------LELDPDDAE---- 43

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217264602 232 rrllghLYNDLGLGYSQLQLFPLAVEAFLQALPLCwvpGEQATVLRNLGMAHNALGNYQEAREFHQKAADLHGsvgqrwE 311
Cdd:COG0457    44 ------ALYNLGLAYLRLGRYEEALADYEQALELD---PDDAEALNNLGLALQALGRYEEALEDYDKALELDP------D 108

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217264602 312 QGRSFGSLAFALSQLGDHKAARDNYLHALQAARDSGDmkgqwqACEGLGAAAARLGQYDqalkyykEALAQCQKEPDSVR 391
Cdd:COG0457   109 DAEALYNLGLALLELGRYDEAIEAYERALELDPDDAD------ALYNLGIALEKLGRYE-------EALELLEKLEAAAL 175

                         250       260
                  ....*....|....*....|
gi 2217264602 392 ERLVAKLADTVRTRLAQVGL 411
Cdd:COG0457   176 AALLAAALGEAALALAAAEV 195
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 121-382 2.30e-09

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 58.20  E-value: 2.30e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217264602 121 FNVALAYHALGELPQALAWYHRALghyQPQGDQGEAWAKMGACYQALGQPELAAHCLQEASQAYAQERQLRAAALALgaa 200
Cdd:COG2956    12 YFKGLNYLLNGQPDKAIDLLEEAL---ELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQD--- 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217264602 201 agcMLKSGRHRvgEVVQVLEKSRRLAERSTE-RRLLGHLYNDLGLgysqlqlFPLAVEAFLQALPLCwvpGEQATVLRNL 279
Cdd:COG2956    86 ---YLKAGLLD--RAEELLEKLLELDPDDAEaLRLLAEIYEQEGD-------WEKAIEVLERLLKLG---PENAHAYCEL 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217264602 280 GMAHNALGNYQEAREFHQKAADLHgsvgqrWEQGRSFGSLAFALSQLGDHKAARDNYLHALQAARDSGdmkgqwQACEGL 359
Cdd:COG2956   151 AELYLEQGDYDEAIEALEKALKLD------PDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYL------PALPRL 218

                         250       260
                  ....*....|....*....|...
gi 2217264602 360 GAAAARLGQYDQALKYYKEALAQ 382
Cdd:COG2956   219 AELYEKLGDPEEALELLRKALEL 241
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 223-382 4.12e-09

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 58.85  E-value: 4.12e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217264602 223 RRLAERSTERRLLGHLYNDLGLGYSQLQLFPLAVEAFLQALPLCWVPGEQATVLRNLGMAHNAL---GNYQEAREFHQKA 299
Cdd:COG3914    25 ELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLLqalGRYEEALALYRRA 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217264602 300 ADLHGSVGQRWEQgrsfgsLAFALSQLGDHKAARDNYLHALQAARDsgdmkgQWQACEGLGAAAARLGQYDQALKYYKEA 379
Cdd:COG3914   105 LALNPDNAEALFN------LGNLLLALGRLEEALAALRRALALNPD------FAEAYLNLGEALRRLGRLEEAIAALRRA 172


                  ...
gi 2217264602 380 LAQ 382
Cdd:COG3914   173 LEL 175
TPR_12 pfam13424
Tetratricopeptide repeat;
271-345 8.31e-08

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 49.31  E-value: 8.31e-08
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2217264602 271 EQATVLRNLGMAHNALGNYQEAREFHQKAADLHGSV--GQRWEQGRSFGSLAFALSQLGDHKAARDNYLHALQAARD 345
Cdd:pfam13424   1 DVATALNNLAAVLRRLGRYDEALELLEKALEIARRLlgPDHPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 271-400 1.14e-07

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 50.39  E-value: 1.14e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217264602 271 EQATVLRNLGMAHNALGNYQEAREFHQKAADLHGSVGQRWeqgrsfGSLAFALSQLGDHKAARDNYLHALqaARDSGDMK 350
Cdd:COG4235    15 NDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADAL------LDLAEALLAAGDTEEAEELLERAL--ALDPDNPE 86

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 2217264602 351 GQWQacegLGAAAARLGQYDQALKYYKEALAqcQKEPDSVRERLVAKLAD 400
Cdd:COG4235    87 ALYL----LGLAAFQQGDYAEAIAAWQKLLA--LLPADAPARLLEASIAE 130
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
37-180 1.56e-07

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 52.32  E-value: 1.56e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217264602  37 QALTRAGHGALQAGQNHEALNNFQRAFLLASKAPQTRdtpvlqacaFNLGAAYVETGDPARGLELLLRAHpeekAQGRRH 116
Cdd:COG0457     9 EAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEAL---------YNLGLAYLRLGRYEEALADYEQAL----ELDPDD 75

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2217264602 117 GDQCFNVALAYHALGELPQALAWYHRALGHyqpQGDQGEAWAKMGACYQALGQPELAAHCLQEA 180
Cdd:COG0457    76 AEALNNLGLALQALGRYEEALEDYDKALEL---DPDDAEALYNLGLALLELGRYDEAIEAYERA 136
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
238-381 4.36e-07

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 50.68  E-value: 4.36e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217264602 238 LYNDLGLGYSQLQLFPLAVEAFLQALPLCwvPgEQATVLRNLGMAHNALGNYQEAREFHQKAADLhgsvgqRWEQGRSFG 317
Cdd:COG4785    75 LYYERGVAYDSLGDYDLAIADFDQALELD--P-DLAEAYNNRGLAYLLLGDYDAALEDFDRALEL------DPDYAYAYL 145

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2217264602 318 SLAFALSQLGDHKAARDNYLHALQAARDSGDMKGQWQACEGL--------------GAAAARLGQYDQALKYYKEALA 381
Cdd:COG4785   146 NRGIALYYLGRYELAIADLEKALELDPNDPERALWLYLAERKldpekalallledwATAYLLQGDTEEARELFKLALA 223
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 35-190 4.94e-06

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 48.19  E-value: 4.94e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217264602  35 SIQALTRAGHGALQAGQNHEALNNFQRAFLLASKAPQTRdtpvlqacaFNLGAAYVETGDPARGLELLLRAHPEEKAQGR 114
Cdd:COG2956   109 DAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAY---------CELAELYLEQGDYDEAIEALEKALKLDPDCAR 179

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2217264602 115 RHgdqcFNVALAYHALGELPQALAWYHRALghyQPQGDQGEAWAKMGACYQALGQPELAAHCLQEASQAYAQERQL 190
Cdd:COG2956   180 AL----LLLAELYLEQGDYEEAIAALERAL---EQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSDDLL 248
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 270-388 8.15e-06

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 45.57  E-value: 8.15e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217264602 270 GEQATVLRNLGMAHNALGNYQEAREFHQKAADLHGsvgqrwEQGRSFGSLAFALSQLGDHKAARDNYLHALQAARDSgdm 349
Cdd:COG4783     1 AACAEALYALAQALLLAGDYDEAEALLEKALELDP------DNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDE--- 71

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 2217264602 350 kgqWQACEGLGAAAARLGQYDQALKYYKEALAQCQKEPD 388
Cdd:COG4783    72 ---PEARLNLGLALLKAGDYDEALALLEKALKLDPEHPE 107
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 242-394 1.41e-05

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 46.65  E-value: 1.41e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217264602 242 LGLGYSQLQLFPLAVEAFLQALPLcwvPGEQATVLRNLGMAHNALGNYQEAREFHQKAADLHGSVGQRWEQgrsfgsLAF 321
Cdd:COG2956    14 KGLNYLLNGQPDKAIDLLEEALEL---DPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLE------LAQ 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217264602 322 ALSQLGDHKAARDNYLHALQAARDSGD----------MKGQWQA-------------------CEgLGAAAARLGQYDQA 372
Cdd:COG2956    85 DYLKAGLLDRAEELLEKLLELDPDDAEalrllaeiyeQEGDWEKaievlerllklgpenahayCE-LAELYLEQGDYDEA 163

                         170       180
                  ....*....|....*....|..
gi 2217264602 373 LKYYKEALaqcQKEPDSVRERL 394
Cdd:COG2956   164 IEALEKAL---KLDPDCARALL 182
TPR_12 pfam13424
Tetratricopeptide repeat;
319-385 3.08e-05

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 41.99  E-value: 3.08e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2217264602 319 LAFALSQLGDHKAARDNYLHALQAARDSGDMKGQWQAC--EGLGAAAARLGQYDQALKYYKEALAQCQK 385
Cdd:pfam13424   9 LAAVLRRLGRYDEALELLEKALEIARRLLGPDHPLTATtlLNLGRLYLELGRYEEALELLERALALAEK 77
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 222-381 9.66e-05

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 42.64  E-value: 9.66e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217264602 222 SRRLAERSTERRLLGHLYNDLGLGYSQLQLFPLAVEAFLQALPLCWVPGEQATVLRNLGMAHNALGNYQEAREFHQKAAD 301
Cdd:COG5010     3 ALEGFDRLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQ 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217264602 302 LHGsvgqrwEQGRSFGSLAFALSQLGDHKAARDNYLHALQAARDSgdmkgqWQACEGLGAAAARLGQYDQALKYYKEALA 381
Cdd:COG5010    83 LDP------NNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDN------PNAYSNLAALLLSLGQDDEAKAALQRALG 150
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 33-187 1.35e-04

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 42.10  E-value: 1.35e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217264602  33 EASIQALTRAGHGALQAGQNHEALNNFQRAFLLASKAPQTRdtpvlqacaFNLGAAYVETGDPARGLELLLRAHpeekAQ 112
Cdd:COG4783     1 AACAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAF---------ALLGEILLQLGDLDEAIVLLHEAL----EL 67

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2217264602 113 GRRHGDQCFNVALAYHALGELPQALAWYHRALGHYQpqgDQGEAWAKMGACYQALGQPELAAHCLQEASQAYAQE 187
Cdd:COG4783    68 DPDEPEARLNLGLALLKAGDYDEALALLEKALKLDP---EHPEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
282-381 1.38e-04

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 40.92  E-value: 1.38e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217264602 282 AHNALGNYQEAREFHQKAADLHgsvgqrWEQGRSFGSLAFALSQLGDHKAARDnYLHALQAARDSgdmkgqWQACEGLGA 361
Cdd:COG3063     1 LYLKLGDLEEAEEYYEKALELD------PDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNN------AEALLNLAE 67

                          90       100
                  ....*....|....*....|
gi 2217264602 362 AAARLGQYDQALKYYKEALA 381
Cdd:COG3063    68 LLLELGDYDEALAYLERALE 87
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 271-382 3.23e-04

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 40.95  E-value: 3.23e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217264602 271 EQATVLRNLGMAHNALGNYQEAREFHQKAADLHGsvgqrwEQGRSFGSLAFALSQLGDHKAARDNYLHALQAARDSGDmk 350
Cdd:COG4783    36 DNPEAFALLGEILLQLGDLDEAIVLLHEALELDP------DEPEARLNLGLALLKAGDYDEALALLEKALKLDPEHPE-- 107

                          90       100       110
                  ....*....|....*....|....*....|..
gi 2217264602 351 gqwqACEGLGAAAARLGQYDQALKYYKEALAQ 382
Cdd:COG4783   108 ----AYLRLARAYRALGRPDEAIAALEKALEL 135
COG3899 COG3899
Predicted ATPase [General function prediction only];
36-451 3.25e-04

Predicted ATPase [General function prediction only];


Pssm-ID: 443106 [Multi-domain]  Cd Length: 1244  Bit Score: 43.31  E-value: 3.25e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217264602   36 IQALTRAGHGALQAGQNHEALNNFQRAFLLASKAPQTRDTPVLQAcafNLGAAYVETGDPARGLELLLRAHPEEkaqgrr 115
Cdd:COG3899    705 ARLLLRAARRALARGAYAEALRYLERALELLPPDPEEEYRLALLL---ELAEALYLAGRFEEAEALLERALAAR------ 775

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217264602  116 hgdqcFNVALAYHALGELPQALAWYHRALGHYQPQGDQGEAWAKMG-ACYQALGQPELAAHCLQEASQAYAQERQLRAAA 194
Cdd:COG3899    776 -----ALAALAALRHGNPPASARAYANLGLLLLGDYEEAYEFGELAlALAERLGDRRLEARALFNLGFILHWLGPLREAL 850

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217264602  195 LALGAAAGCMLKSGRHRVGEVVQVLEKSRRLAERSTERRLLGHLYNDLGLGYSQLQLFPLAVEAFLQALPLCWVPGEQAT 274
Cdd:COG3899    851 ELLREALEAGLETGDAALALLALAAAAAAAAAAAALAAAAAAAARLLAAAAAALAAAAAAAALAAAELARLAAAAAAAAA 930

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217264602  275 VLRNLGMAHNALGNYQEAREFHQKAADLHGSVGQRWEQGRSFGSLAFALSQLGDHKAARDNYLHALQAARDSGDMKGQWQ 354
Cdd:COG3899    931 LALAAAAAAAAAAALAAAAAAAALAAALALAAAAAAAAAAALAAAAAAAAAAAAAAAAAALEAAAAALLALLAAAAAAAA 1010

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217264602  355 ACEGLGAAAARLGQYDQALKYYKEALAQCQKEPDSVRERLVAKLADTVRTRLAQVGLVQTHTLTSAPGRLQAPGGASQAE 434
Cdd:COG3899   1011 AAAALAAALLAAALAALAAAAAAAALLAAAAALALLAALAAAAAAAAAAAALAAAAALLAAAAAAAAAAAAAAAAAALAA 1090

                          410
                   ....*....|....*..
gi 2217264602  435 GTPAKAGSSTAGVQHRS 451
Cdd:COG3899   1091 ALAAAALAAAAAAALAL 1107
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 88-184 9.39e-04

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 38.82  E-value: 9.39e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217264602  88 AYVETGDP---ARGLELLLRAHPEEKAQGRRHgdqcFNVALAYHALGELPQALAWYHRALGHYQPQGDQGEAWAKMGACY 164
Cdd:COG1729     2 ALLKAGDYdeaIAAFKAFLKRYPNSPLAPDAL----YWLGEAYYALGDYDEAAEAFEKLLKRYPDSPKAPDALLKLGLSY 77

                          90       100
                  ....*....|....*....|
gi 2217264602 165 QALGQPELAAHCLQEASQAY 184
Cdd:COG1729    78 LELGDYDKARATLEELIKKY 97
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
246-345 1.12e-03

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 38.23  E-value: 1.12e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217264602 246 YSQLQLFPLAVEAFLQALPLcwVPgEQATVLRNLGMAHNALGNYQEAREFhQKAADLHGsvgqrwEQGRSFGSLAFALSQ 325
Cdd:COG3063     2 YLKLGDLEEAEEYYEKALEL--DP-DNADALNNLGLLLLEQGRYDEAIAL-EKALKLDP------NNAEALLNLAELLLE 71

                          90       100
                  ....*....|....*....|
gi 2217264602 326 LGDHKAARDNYLHALQAARD 345
Cdd:COG3063    72 LGDYDEALAYLERALELDPS 91
TPR_1 pfam00515
Tetratricopeptide repeat;
354-380 2.50e-03

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 35.47  E-value: 2.50e-03
                          10        20
                  ....*....|....*....|....*..
gi 2217264602 354 QACEGLGAAAARLGQYDQALKYYKEAL 380
Cdd:pfam00515   2 KALYNLGNAYFKLGKYDEALEYYEKAL 28
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 118-303 2.55e-03

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 38.25  E-value: 2.55e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217264602 118 DQCFNVALAYHALGELPQALAWYHRALghyQPQGDQGEAWAKMGACYQALGQPELAAHCLQEASQAYAQERQlraaalal 197
Cdd:COG4783     5 EALYALAQALLLAGDYDEAEALLEKAL---ELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPE-------- 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217264602 198 gaaagcmlksgrhrvgevvqvleksrrlaersterrllghLYNDLGLGYSQLQLFPLAVEAFLQALPLCwvpGEQATVLR 277
Cdd:COG4783    74 ----------------------------------------ARLNLGLALLKAGDYDEALALLEKALKLD---PEHPEAYL 110

                         170       180
                  ....*....|....*....|....*.
gi 2217264602 278 NLGMAHNALGNYQEAREFHQKAADLH 303
Cdd:COG4783   111 RLARAYRALGRPDEAIAALEKALELD 136
TPR_10 pfam13374
Tetratricopeptide repeat;
273-303 2.72e-03

Tetratricopeptide repeat;


Pssm-ID: 463861 [Multi-domain]  Cd Length: 42  Bit Score: 35.56  E-value: 2.72e-03
                          10        20        30
                  ....*....|....*....|....*....|.
gi 2217264602 273 ATVLRNLGMAHNALGNYQEAREFHQKAADLH 303
Cdd:pfam13374   2 ASSLNNLANALRAQGRYDEAEELLEEALAIR 32
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 353-381 2.93e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 35.11  E-value: 2.93e-03
                           10        20
                   ....*....|....*....|....*....
gi 2217264602  353 WQACEGLGAAAARLGQYDQALKYYKEALA 381
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALE 29
COG4700 COG4700
Uncharacterized conserved protein ECs_4300, contains TPR-like domain [Function unknown];
47-179 3.57e-03

Uncharacterized conserved protein ECs_4300, contains TPR-like domain [Function unknown];


Pssm-ID: 443735 [Multi-domain]  Cd Length: 249  Bit Score: 39.09  E-value: 3.57e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217264602  47 LQAGQNHEALNNFQRAFllasKAPQTRDTPVLqacaFNLGAAYVETGDPARGLELL---LRAHPEekaqgRRHGDQCFNV 123
Cdd:COG4700   100 LELGRYDEAIELYEEAL----TGIFADDPHIL----LGLAQALFELGRYAEALETLeklIAKNPD-----FKSSDAHLLY 166

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2217264602 124 ALAYHALGELPQALAWYHRALGHYqpqgDQGEAWAKMGACYQALGQPELAAHCLQE 179
Cdd:COG4700   167 ARALEALGDLEAAEAELEALARRY----SGPEARYRYAKFLARQGRTAEAKELLEE 218
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 273-302 4.85e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 34.73  E-value: 4.85e-03
                           10        20        30
                   ....*....|....*....|....*....|
gi 2217264602  273 ATVLRNLGMAHNALGNYQEAREFHQKAADL 302
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALEL 30
TPR_12 pfam13424
Tetratricopeptide repeat;
122-186 5.00e-03

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 35.83  E-value: 5.00e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217264602 122 NVALAYHALGELPQALAWYHRALGHYQPQG-----DQGEAWAKMGACYQALGQPELAAHCLQEASQAYAQ 186
Cdd:pfam13424   8 NLAAVLRRLGRYDEALELLEKALEIARRLLgpdhpLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 164-303 9.77e-03

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 36.86  E-value: 9.77e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217264602 164 YQALGQPELAAHCLQEASQAYAQERQLRAAALALGAAAGCMLKSGRHRVGEVVQVLEKSRRLAERSTErrllghLYNDLG 243
Cdd:COG5010    22 TLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPE------LYYNLA 95

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217264602 244 LGYSQLQLFPLAVEAFLQALPLCwvpGEQATVLRNLGMAHNALGNYQEAREFHQKAADLH 303
Cdd:COG5010    96 LLYSRSGDKDEAKEYYEKALALS---PDNPNAYSNLAALLLSLGQDDEAKAALQRALGTS 152
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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