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Conserved domains on  [gi|2217337325|ref|XP_047296634|]
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heat shock factor 2-binding protein isoform X8 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
COG6 super family cl19764
Conserved oligomeric complex COG6; COG6 is a component of the conserved oligomeric golgi ...
 47-106 8.35e-03

Conserved oligomeric complex COG6; COG6 is a component of the conserved oligomeric golgi complex, which is composed of eight different subunits and is required for normal golgi morphology and localization.


The actual alignment was detected with superfamily member pfam06419:

Pssm-ID: 473207  Cd Length: 611  Bit Score: 37.20  E-value: 8.35e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2217337325  47 NGEVLESFQKLKiveKNLERKEQELEQLKMDCEHFKARLETV---------QADNIREKKEKLALRQQL 106
Cdd:pfam06419  32 NGEFLKEFGPVV---EQLKRIETDVEKLNNSCDEMRKRLSAAkedtaplleEASSLQEQKKKIELKQKL 97
 
Name Accession Description Interval E-value
COG6 pfam06419
Conserved oligomeric complex COG6; COG6 is a component of the conserved oligomeric golgi ...
 47-106 8.35e-03

Conserved oligomeric complex COG6; COG6 is a component of the conserved oligomeric golgi complex, which is composed of eight different subunits and is required for normal golgi morphology and localization.


Pssm-ID: 461904  Cd Length: 611  Bit Score: 37.20  E-value: 8.35e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2217337325  47 NGEVLESFQKLKiveKNLERKEQELEQLKMDCEHFKARLETV---------QADNIREKKEKLALRQQL 106
Cdd:pfam06419  32 NGEFLKEFGPVV---EQLKRIETDVEKLNNSCDEMRKRLSAAkedtaplleEASSLQEQKKKIELKQKL 97
PRK12704 PRK12704
phosphodiesterase; Provisional
 17-118 8.48e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 37.07  E-value: 8.48e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217337325  17 KEEFVKvRKKDLERlttEVmqirdflpRILNGEVLESFQKLKIVEKNLERKEQELEQLKMDCEHFKARLETVQaDNIREK 96
Cdd:PRK12704   63 KEEIHK-LRNEFEK---EL--------RERRNELQKLEKRLLQKEENLDRKLELLEKREEELEKKEKELEQKQ-QELEKK 129

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 2217337325  97 KEKL-ALRQQLN------------EAKQQLLQQAE 118
Cdd:PRK12704  130 EEELeELIEEQLqelerisgltaeEAKEILLEKVE 164
 
Name Accession Description Interval E-value
COG6 pfam06419
Conserved oligomeric complex COG6; COG6 is a component of the conserved oligomeric golgi ...
 47-106 8.35e-03

Conserved oligomeric complex COG6; COG6 is a component of the conserved oligomeric golgi complex, which is composed of eight different subunits and is required for normal golgi morphology and localization.


Pssm-ID: 461904  Cd Length: 611  Bit Score: 37.20  E-value: 8.35e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2217337325  47 NGEVLESFQKLKiveKNLERKEQELEQLKMDCEHFKARLETV---------QADNIREKKEKLALRQQL 106
Cdd:pfam06419  32 NGEFLKEFGPVV---EQLKRIETDVEKLNNSCDEMRKRLSAAkedtaplleEASSLQEQKKKIELKQKL 97
PRK12704 PRK12704
phosphodiesterase; Provisional
 17-118 8.48e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 37.07  E-value: 8.48e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217337325  17 KEEFVKvRKKDLERlttEVmqirdflpRILNGEVLESFQKLKIVEKNLERKEQELEQLKMDCEHFKARLETVQaDNIREK 96
Cdd:PRK12704   63 KEEIHK-LRNEFEK---EL--------RERRNELQKLEKRLLQKEENLDRKLELLEKREEELEKKEKELEQKQ-QELEKK 129

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 2217337325  97 KEKL-ALRQQLN------------EAKQQLLQQAE 118
Cdd:PRK12704  130 EEELeELIEEQLqelerisgltaeEAKEILLEKVE 164
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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