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Conserved domains on  [gi|2217301912|ref|XP_047288743|]
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protein Lines homolog 1 isoform X3 [Homo sapiens]

Protein Classification

BLUF domain-containing protein( domain architecture ID 10631368)

BLUF domain-containing protein similar to Rhodobacter sphaeroides transcriptional antirepressor AppA that senses both the light climate and the intracellular redox state

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
LINES_N pfam14694
Lines N-terminus; This family represents the N-terminus of protein lines. In Drosophila this ...
193-409 1.05e-119

Lines N-terminus; This family represents the N-terminus of protein lines. In Drosophila this protein is involved in embryonic segmentation and may function as a transcriptional regulator.


:

Pssm-ID: 464266  Cd Length: 351  Bit Score: 351.62  E-value: 1.05e-119
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217301912 193 TLTAIIKEIFKDSCSQKTEILKQFLTHFDTIFEVFYNSLFSQHFENCRDTSKIVNILMCFLDLLELLIASRIHLKLHFTC 272
Cdd:pfam14694   1 TLTAVIKEILKDTCSQKTEILKQLLAPLDTLFEVFYNSLFSQHFENSQQTSKLTNSLISFLDLLELLIASRINLSLHFIC 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217301912 273 QRILFLKPSCMLEVITWPIQAFVKRKVIIFLKKCLLCKVGEDLCRGSVPALMPPDHHVAVDMLALANAVLQAVNSGLLKT 352
Cdd:pfam14694  81 QRPLFLKLSCFLDLLNSPVPYFVKKKLILLLKKCLLYKSGEDLCRGSVPATLALDDMLDEDMLALAHAVLQAVDLGLLDS 160
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2217301912 353 LSVYEKHSFFGGDEVQPECELITSPDHVILRAASLVIMKSLEIKFQNYSSASEVKGA 409
Cdd:pfam14694 161 LPVRGKPSRFGGSEVQPGCGGRGGPDHVLLRAASLLVLKSLEIKVQETRSASEIKRS 217
 
Name Accession Description Interval E-value
LINES_N pfam14694
Lines N-terminus; This family represents the N-terminus of protein lines. In Drosophila this ...
193-409 1.05e-119

Lines N-terminus; This family represents the N-terminus of protein lines. In Drosophila this protein is involved in embryonic segmentation and may function as a transcriptional regulator.


Pssm-ID: 464266  Cd Length: 351  Bit Score: 351.62  E-value: 1.05e-119
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217301912 193 TLTAIIKEIFKDSCSQKTEILKQFLTHFDTIFEVFYNSLFSQHFENCRDTSKIVNILMCFLDLLELLIASRIHLKLHFTC 272
Cdd:pfam14694   1 TLTAVIKEILKDTCSQKTEILKQLLAPLDTLFEVFYNSLFSQHFENSQQTSKLTNSLISFLDLLELLIASRINLSLHFIC 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217301912 273 QRILFLKPSCMLEVITWPIQAFVKRKVIIFLKKCLLCKVGEDLCRGSVPALMPPDHHVAVDMLALANAVLQAVNSGLLKT 352
Cdd:pfam14694  81 QRPLFLKLSCFLDLLNSPVPYFVKKKLILLLKKCLLYKSGEDLCRGSVPATLALDDMLDEDMLALAHAVLQAVDLGLLDS 160
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2217301912 353 LSVYEKHSFFGGDEVQPECELITSPDHVILRAASLVIMKSLEIKFQNYSSASEVKGA 409
Cdd:pfam14694 161 LPVRGKPSRFGGSEVQPGCGGRGGPDHVLLRAASLLVLKSLEIKVQETRSASEIKRS 217
 
Name Accession Description Interval E-value
LINES_N pfam14694
Lines N-terminus; This family represents the N-terminus of protein lines. In Drosophila this ...
193-409 1.05e-119

Lines N-terminus; This family represents the N-terminus of protein lines. In Drosophila this protein is involved in embryonic segmentation and may function as a transcriptional regulator.


Pssm-ID: 464266  Cd Length: 351  Bit Score: 351.62  E-value: 1.05e-119
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217301912 193 TLTAIIKEIFKDSCSQKTEILKQFLTHFDTIFEVFYNSLFSQHFENCRDTSKIVNILMCFLDLLELLIASRIHLKLHFTC 272
Cdd:pfam14694   1 TLTAVIKEILKDTCSQKTEILKQLLAPLDTLFEVFYNSLFSQHFENSQQTSKLTNSLISFLDLLELLIASRINLSLHFIC 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217301912 273 QRILFLKPSCMLEVITWPIQAFVKRKVIIFLKKCLLCKVGEDLCRGSVPALMPPDHHVAVDMLALANAVLQAVNSGLLKT 352
Cdd:pfam14694  81 QRPLFLKLSCFLDLLNSPVPYFVKKKLILLLKKCLLYKSGEDLCRGSVPATLALDDMLDEDMLALAHAVLQAVDLGLLDS 160
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2217301912 353 LSVYEKHSFFGGDEVQPECELITSPDHVILRAASLVIMKSLEIKFQNYSSASEVKGA 409
Cdd:pfam14694 161 LPVRGKPSRFGGSEVQPGCGGRGGPDHVLLRAASLLVLKSLEIKVQETRSASEIKRS 217
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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