NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|2217289717|ref|XP_047285015|]
View 

protein FAM90A1 isoform X1 [Homo sapiens]

Protein Classification

transcription initiation factor TFIID subunit 1( domain architecture ID 10633817)

transcription initiation factor TFIID subunit 1 (TAF1) is part of the TFIID complex that plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
zf-CCHC_6 pfam15288
Zinc knuckle; This Zinc knuckle is found in FAM90A mammalian proteins.
 41-82 8.74e-17

Zinc knuckle; This Zinc knuckle is found in FAM90A mammalian proteins.


:

Pssm-ID: 464616 [Multi-domain]  Cd Length: 42  Bit Score: 73.57  E-value: 8.74e-17
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 2217289717  41 RLKCKNCEAFGHTARSTRCPMKCWKAALVPPNFGEKEGKENL 82
Cdd:pfam15288   1 RVKCKNCGAFGHTARSKRCPIKCWNGALVPQPLGSKKEKENL 42
PHA03247 super family cl33720
large tegument protein UL36; Provisional
 25-371 9.45e-06

large tegument protein UL36; Provisional


The actual alignment was detected with superfamily member PHA03247:

Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 48.40  E-value: 9.45e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217289717   25 RAPVGPRAPPPDEEDPRLKcknceAFGHTARSTRCPMKCWKAALVPPNFGEKEGKENLKPwkPQVEANPGPLNKDKGEKE 104
Cdd:PHA03247  2609 RGPAPPSPLPPDTHAPDPP-----PPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSR--PRRARRLGRAAQASSPPQ 2681

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217289717  105 ERPRPQDPQRKALLHIFSRKPPEKPLPnQKGSTESSDYLRVASGPMPVHTTSKRPRVDPVLSDRSATEMSDRGSvlaSLS 184
Cdd:PHA03247  2682 RPRRRAARPTVGSLTSLADPPPPPPTP-EPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGP---ARP 2757

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217289717  185 PLRKASLSSSSSLGPKERQTGAAADIPQTAVRHQGPEPLLVVKPTHSSPAGGCREVPQAASKTHGLLQAVSPQAQDKRPA 264
Cdd:PHA03247  2758 ARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPT 2837

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217289717  265 VTSQPCPPAATHSLGLGSNLSFGPGAKRSAPAPIQACLNFPKKPRLGPFQIPESAIQGGELGAPENLQPPPAATELGPRT 344
Cdd:PHA03247  2838 APPPPPGPPPPSLPLGGSVAPGGDVRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPP 2917

                          330       340
                   ....*....|....*....|....*..
gi 2217289717  345 SPQTGTRTPAQVLSGDRQPPHSRPCLP 371
Cdd:PHA03247  2918 QPQPQPPPPPQPQPPPPPPPRPQPPLA 2944
 
Name Accession Description Interval E-value
zf-CCHC_6 pfam15288
Zinc knuckle; This Zinc knuckle is found in FAM90A mammalian proteins.
 41-82 8.74e-17

Zinc knuckle; This Zinc knuckle is found in FAM90A mammalian proteins.


Pssm-ID: 464616 [Multi-domain]  Cd Length: 42  Bit Score: 73.57  E-value: 8.74e-17
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 2217289717  41 RLKCKNCEAFGHTARSTRCPMKCWKAALVPPNFGEKEGKENL 82
Cdd:pfam15288   1 RVKCKNCGAFGHTARSKRCPIKCWNGALVPQPLGSKKEKENL 42
PHA03247 PHA03247
large tegument protein UL36; Provisional
 25-371 9.45e-06

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 48.40  E-value: 9.45e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217289717   25 RAPVGPRAPPPDEEDPRLKcknceAFGHTARSTRCPMKCWKAALVPPNFGEKEGKENLKPwkPQVEANPGPLNKDKGEKE 104
Cdd:PHA03247  2609 RGPAPPSPLPPDTHAPDPP-----PPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSR--PRRARRLGRAAQASSPPQ 2681

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217289717  105 ERPRPQDPQRKALLHIFSRKPPEKPLPnQKGSTESSDYLRVASGPMPVHTTSKRPRVDPVLSDRSATEMSDRGSvlaSLS 184
Cdd:PHA03247  2682 RPRRRAARPTVGSLTSLADPPPPPPTP-EPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGP---ARP 2757

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217289717  185 PLRKASLSSSSSLGPKERQTGAAADIPQTAVRHQGPEPLLVVKPTHSSPAGGCREVPQAASKTHGLLQAVSPQAQDKRPA 264
Cdd:PHA03247  2758 ARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPT 2837

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217289717  265 VTSQPCPPAATHSLGLGSNLSFGPGAKRSAPAPIQACLNFPKKPRLGPFQIPESAIQGGELGAPENLQPPPAATELGPRT 344
Cdd:PHA03247  2838 APPPPPGPPPPSLPLGGSVAPGGDVRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPP 2917

                          330       340
                   ....*....|....*....|....*..
gi 2217289717  345 SPQTGTRTPAQVLSGDRQPPHSRPCLP 371
Cdd:PHA03247  2918 QPQPQPPPPPQPQPPPPPPPRPQPPLA 2944
 
Name Accession Description Interval E-value
zf-CCHC_6 pfam15288
Zinc knuckle; This Zinc knuckle is found in FAM90A mammalian proteins.
 41-82 8.74e-17

Zinc knuckle; This Zinc knuckle is found in FAM90A mammalian proteins.


Pssm-ID: 464616 [Multi-domain]  Cd Length: 42  Bit Score: 73.57  E-value: 8.74e-17
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 2217289717  41 RLKCKNCEAFGHTARSTRCPMKCWKAALVPPNFGEKEGKENL 82
Cdd:pfam15288   1 RVKCKNCGAFGHTARSKRCPIKCWNGALVPQPLGSKKEKENL 42
PHA03247 PHA03247
large tegument protein UL36; Provisional
 25-371 9.45e-06

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 48.40  E-value: 9.45e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217289717   25 RAPVGPRAPPPDEEDPRLKcknceAFGHTARSTRCPMKCWKAALVPPNFGEKEGKENLKPwkPQVEANPGPLNKDKGEKE 104
Cdd:PHA03247  2609 RGPAPPSPLPPDTHAPDPP-----PPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSR--PRRARRLGRAAQASSPPQ 2681

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217289717  105 ERPRPQDPQRKALLHIFSRKPPEKPLPnQKGSTESSDYLRVASGPMPVHTTSKRPRVDPVLSDRSATEMSDRGSvlaSLS 184
Cdd:PHA03247  2682 RPRRRAARPTVGSLTSLADPPPPPPTP-EPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGP---ARP 2757

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217289717  185 PLRKASLSSSSSLGPKERQTGAAADIPQTAVRHQGPEPLLVVKPTHSSPAGGCREVPQAASKTHGLLQAVSPQAQDKRPA 264
Cdd:PHA03247  2758 ARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPT 2837

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217289717  265 VTSQPCPPAATHSLGLGSNLSFGPGAKRSAPAPIQACLNFPKKPRLGPFQIPESAIQGGELGAPENLQPPPAATELGPRT 344
Cdd:PHA03247  2838 APPPPPGPPPPSLPLGGSVAPGGDVRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPP 2917

                          330       340
                   ....*....|....*....|....*..
gi 2217289717  345 SPQTGTRTPAQVLSGDRQPPHSRPCLP 371
Cdd:PHA03247  2918 QPQPQPPPPPQPQPPPPPPPRPQPPLA 2944
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH