pre-mRNA-processing factor 40 homolog B isoform X9 [Homo sapiens]
pre-mRNA-processing factor 40 family protein( domain architecture ID 13418230)
pre-mRNA-processing factor 40 (PRPF40) family protein similar to mammalian PRPF40 homologs A and B that may be involved in pre-mRNA splicing; contains WW and FF domains
List of domain hits
Name | Accession | Description | Interval | E-value | ||||||||
PRP40 super family | cl34905 | Splicing factor [RNA processing and modification]; |
84-576 | 8.14e-46 | ||||||||
Splicing factor [RNA processing and modification]; The actual alignment was detected with superfamily member COG5104: Pssm-ID: 227435 [Multi-domain] Cd Length: 590 Bit Score: 174.11 E-value: 8.14e-46
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FF | smart00441 | Contains two conserved F residues; A novel motif that often accompanies WW domains. Often ... |
628-676 | 1.21e-05 | ||||||||
Contains two conserved F residues; A novel motif that often accompanies WW domains. Often contains two conserved Phe (F) residues. : Pssm-ID: 128718 [Multi-domain] Cd Length: 55 Bit Score: 43.33 E-value: 1.21e-05
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Name | Accession | Description | Interval | E-value | ||||||||
PRP40 | COG5104 | Splicing factor [RNA processing and modification]; |
84-576 | 8.14e-46 | ||||||||
Splicing factor [RNA processing and modification]; Pssm-ID: 227435 [Multi-domain] Cd Length: 590 Bit Score: 174.11 E-value: 8.14e-46
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FF | pfam01846 | FF domain; This domain has been predicted to be involved in protein-protein interaction. This ... |
273-322 | 2.41e-14 | ||||||||
FF domain; This domain has been predicted to be involved in protein-protein interaction. This domain was recently shown to bind the hyperphosphorylated C-terminal repeat domain of RNA polymerase II, confirming its role in protein-protein interactions. Pssm-ID: 426471 [Multi-domain] Cd Length: 50 Bit Score: 67.87 E-value: 2.41e-14
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WW | cd00201 | Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; ... |
132-161 | 6.79e-09 | ||||||||
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other peptide recognition proteins such as antibodies and receptors; WW domains have a single groove formed by a conserved Trp and Tyr which recognizes a pair of residues of the sequence X-Pro; variable loops and neighboring domains confer specificity in this domain; there are five distinct groups based on binding: 1) PPXY motifs 2) the PPLP motif; 3) PGM motifs; 4) PSP or PTP motifs; 5) PR motifs. Pssm-ID: 238122 [Multi-domain] Cd Length: 31 Bit Score: 51.76 E-value: 6.79e-09
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FF | smart00441 | Contains two conserved F residues; A novel motif that often accompanies WW domains. Often ... |
272-325 | 1.77e-08 | ||||||||
Contains two conserved F residues; A novel motif that often accompanies WW domains. Often contains two conserved Phe (F) residues. Pssm-ID: 128718 [Multi-domain] Cd Length: 55 Bit Score: 51.42 E-value: 1.77e-08
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FF | smart00441 | Contains two conserved F residues; A novel motif that often accompanies WW domains. Often ... |
628-676 | 1.21e-05 | ||||||||
Contains two conserved F residues; A novel motif that often accompanies WW domains. Often contains two conserved Phe (F) residues. Pssm-ID: 128718 [Multi-domain] Cd Length: 55 Bit Score: 43.33 E-value: 1.21e-05
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Name | Accession | Description | Interval | E-value | ||||||||
PRP40 | COG5104 | Splicing factor [RNA processing and modification]; |
84-576 | 8.14e-46 | ||||||||
Splicing factor [RNA processing and modification]; Pssm-ID: 227435 [Multi-domain] Cd Length: 590 Bit Score: 174.11 E-value: 8.14e-46
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FF | pfam01846 | FF domain; This domain has been predicted to be involved in protein-protein interaction. This ... |
273-322 | 2.41e-14 | ||||||||
FF domain; This domain has been predicted to be involved in protein-protein interaction. This domain was recently shown to bind the hyperphosphorylated C-terminal repeat domain of RNA polymerase II, confirming its role in protein-protein interactions. Pssm-ID: 426471 [Multi-domain] Cd Length: 50 Bit Score: 67.87 E-value: 2.41e-14
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WW | cd00201 | Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; ... |
132-161 | 6.79e-09 | ||||||||
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other peptide recognition proteins such as antibodies and receptors; WW domains have a single groove formed by a conserved Trp and Tyr which recognizes a pair of residues of the sequence X-Pro; variable loops and neighboring domains confer specificity in this domain; there are five distinct groups based on binding: 1) PPXY motifs 2) the PPLP motif; 3) PGM motifs; 4) PSP or PTP motifs; 5) PR motifs. Pssm-ID: 238122 [Multi-domain] Cd Length: 31 Bit Score: 51.76 E-value: 6.79e-09
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WW | pfam00397 | WW domain; The WW domain is a protein module with two highly conserved tryptophans that binds ... |
93-118 | 1.47e-08 | ||||||||
WW domain; The WW domain is a protein module with two highly conserved tryptophans that binds proline-rich peptide motifs in vitro. Pssm-ID: 459800 [Multi-domain] Cd Length: 30 Bit Score: 50.97 E-value: 1.47e-08
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FF | smart00441 | Contains two conserved F residues; A novel motif that often accompanies WW domains. Often ... |
272-325 | 1.77e-08 | ||||||||
Contains two conserved F residues; A novel motif that often accompanies WW domains. Often contains two conserved Phe (F) residues. Pssm-ID: 128718 [Multi-domain] Cd Length: 55 Bit Score: 51.42 E-value: 1.77e-08
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WW | smart00456 | Domain with 2 conserved Trp (W) residues; Also known as the WWP or rsp5 domain. Binds ... |
133-161 | 4.12e-08 | ||||||||
Domain with 2 conserved Trp (W) residues; Also known as the WWP or rsp5 domain. Binds proline-rich polypeptides. Pssm-ID: 197736 [Multi-domain] Cd Length: 33 Bit Score: 49.52 E-value: 4.12e-08
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WW | pfam00397 | WW domain; The WW domain is a protein module with two highly conserved tryptophans that binds ... |
133-159 | 5.73e-08 | ||||||||
WW domain; The WW domain is a protein module with two highly conserved tryptophans that binds proline-rich peptide motifs in vitro. Pssm-ID: 459800 [Multi-domain] Cd Length: 30 Bit Score: 49.04 E-value: 5.73e-08
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WW | cd00201 | Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; ... |
93-118 | 1.10e-07 | ||||||||
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other peptide recognition proteins such as antibodies and receptors; WW domains have a single groove formed by a conserved Trp and Tyr which recognizes a pair of residues of the sequence X-Pro; variable loops and neighboring domains confer specificity in this domain; there are five distinct groups based on binding: 1) PPXY motifs 2) the PPLP motif; 3) PGM motifs; 4) PSP or PTP motifs; 5) PR motifs. Pssm-ID: 238122 [Multi-domain] Cd Length: 31 Bit Score: 48.29 E-value: 1.10e-07
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WW | smart00456 | Domain with 2 conserved Trp (W) residues; Also known as the WWP or rsp5 domain. Binds ... |
93-118 | 2.67e-07 | ||||||||
Domain with 2 conserved Trp (W) residues; Also known as the WWP or rsp5 domain. Binds proline-rich polypeptides. Pssm-ID: 197736 [Multi-domain] Cd Length: 33 Bit Score: 47.21 E-value: 2.67e-07
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FF | pfam01846 | FF domain; This domain has been predicted to be involved in protein-protein interaction. This ... |
487-542 | 9.13e-07 | ||||||||
FF domain; This domain has been predicted to be involved in protein-protein interaction. This domain was recently shown to bind the hyperphosphorylated C-terminal repeat domain of RNA polymerase II, confirming its role in protein-protein interactions. Pssm-ID: 426471 [Multi-domain] Cd Length: 50 Bit Score: 46.30 E-value: 9.13e-07
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FF | smart00441 | Contains two conserved F residues; A novel motif that often accompanies WW domains. Often ... |
628-676 | 1.21e-05 | ||||||||
Contains two conserved F residues; A novel motif that often accompanies WW domains. Often contains two conserved Phe (F) residues. Pssm-ID: 128718 [Multi-domain] Cd Length: 55 Bit Score: 43.33 E-value: 1.21e-05
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Blast search parameters | ||||
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