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Conserved domains on  [gi|2217352778|ref|XP_047272411|]
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uncharacterized protein KIAA0232 isoform X3 [Homo sapiens]

Protein Classification

DUF4603 domain-containing protein( domain architecture ID 10634086)

DUF4603 domain-containing protein similar to Homo sapiens protein KIAA0232

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DUF4603 pfam15376
Domain of unknown function (DUF4603); This protein family is a domain of unknown function. In ...
 27-1322 0e+00

Domain of unknown function (DUF4603); This protein family is a domain of unknown function. In particular, this domain lies at the C-terminal end of a protein found in eukaryotes.


:

Pssm-ID: 464684  Cd Length: 1293  Bit Score: 2254.69  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217352778   27 VSEMSLLHALGPVQTWLGQELEKCGIDAMIYTRYVLSLLLHDSYDYDLQEQENDIFLGWEKGAYKKWGKSKKKCSDLTLE 106
Cdd:pfam15376    5 ASEMSLLQSLGPVQTWLGQELEKCGIDAMIYTRYVLSLLLHDSYDYDLQDQENDIFLGWEKGAGKKWGKSKKKGTDLSLE 84

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217352778  107 EMKKQAAVQCLRSASDESSGIETLVEELCSRLKDLQSKQ--EEKIHKKLEGSPSPEAELSPPAKDQVEMYYEAFPPLSEK 184
Cdd:pfam15376   85 EMKKQAAVQCLRSASDENSGIESLVEELCSKLKDLQNKQkeEKKINKKSEGSQSPERDESPSSKDQVEMYYEAFPPLSEK 164

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217352778  185 PVCLQEIMTVWNKSKVCSYSSSSSSSTAPPAStDTSSPKDCNSESEVTKERSSEVPTTVHEKT-QSKSKNEKENKFSNGT 263
Cdd:pfam15376  165 PVCLQEIMTVWNKAKACSYSSSSSSAAPQTST-DTSSPKDCNSEGEATKERNSEAPATTSERTqQRRSKKEKENRFHNGA 243

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217352778  264 IEEKPALY-KKQIRHKPEGKIRPRSWSSGSSEAGSSSSGNQGELKASMKYVKVRHKARE-IRNKKGRNGQSRLSLKHGEK 341
Cdd:pfam15376  244 AEEKSAVHsKKQVRHRSEGKYRPRSWSSGSSEAGSSSSGNQGDMKTSIKFVKVRHKSREaVRNKKGRNGQVKLALKVIDK 323

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217352778  342 AERNIHTGSSSSSSSGSVK-QLCKRGKRPLKEIgRKDPGSTEGKDLYMENRKDTEYKEEPLWYTEPIAEYFVPLSRKSKL 420
Cdd:pfam15376  324 EERRNAGGSSSSASGGSIKqQLCKKGKRPLKEI-RKDPGWVEGKESGGEARNKKEYMEEPLWYTEPITEYFVPLSRKSKL 402

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217352778  421 ETTYRNRQDTSDL--TSEAVEELSESVHGLCISNNNLHKTYLAAGTFIDGHFVEMPAVINEDIDLTGTSLCSLPEDNKYL 498
Cdd:pfam15376  403 ETKYRSKEDSPDGfaLSIDVEELSERVQGICIANSNIQRAYLAAGTFIDGHFVEMPAEGNEAADLNGTSSCPQPEDNKDL 482

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217352778  499 DDIHLSELTHFYEVDIDQSMLDPGASETMQgESRILNMIRQKSKENTDFEAECCIVLDGMELQGERAIWTDSTSSVGAEG 578
Cdd:pfam15376  483 DDEHLSEFTHFYEVDIYQSILDPSASDSVQ-ESRILNMIRQKSKEQRDFEAECCIVLDGLELQGESAIRADSTSASGAEG 561

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217352778  579 LFLQDLGNLAQFWECCS-SSSGDADGESFGGDSPVRLSPILDSTVLNSHLLAGNQE-LFSDINEGSGIN-SCFSVFEVQC 655
Cdd:pfam15376  562 FLMQDLENIAQVWECCSsSSSEDADGESFGGDSPIRLSPLLDSVSFNLSKLSGNQEeLFSEANEGSGLNsSCFSLFEVQY 641

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217352778  656 SNSVLPFSFETLNLGNENTDSS--ANMLGKTQSRLLIWTKNSAFEENEHCSNLSTRTCSPWSHSEETRSDNETLNIQFEE 733
Cdd:pfam15376  642 DSSTFPFPRDSLTLGHENTDSSscLNPLGNKQSRLLIWTKNSAFDETEHCSNLSTRTCSPWSHSEETRSDNEQFNAQAEE 721

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217352778  734 STQFNAEDINYVVPRVSSNYVDEELLDFLQDETCQQNSRTLGEIPTLVFKKTSKLESVCGIQLEQKtENKNFETTQVC-- 811
Cdd:pfam15376  722 SAQFGNEEINCVIPPLSSTYLEEELLDFLQEESCHQEEVSVSTASNQTFKKKSKLESVCGIALEQD-ESKQYESTGVFsd 800

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217352778  812 NESPHGDGYSSGVIKDIWTKMADTNSVATVEIERTDAELFSADVNNY-CCCLDAEAELETLQEPDKAVRRSEYHLWEGQK 890
Cdd:pfam15376  801 NSNQQGDDYSSGIIKDIWTAIGDRDSVITLGAEKMDEGLFSEEVNSYcCCCLDVEAKGEPLQEQKKAVQRSEYHLWEGQK 880

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217352778  891 ESLEKRAFASSELSNVDGGDYTTPSKPWDVAQDKENTFILGGVYGELKTFNSDGEWAVVPPSHTKGSLLQCAASDVVTIA 970
Cdd:pfam15376  881 ENLEEQALAKNELSKVDGGDYTTPSKPWDVNSDKESTFILGGVYGELKTFSSDGEWAVVPPSDSRGSLLQCAASDVVTIA 960

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217352778  971 GTDVFMTPGNSFAPGHRQLWKPFVSFEQNDQP-KSGENGLNKGFSFIFHEDLLGACGNFQVEDPGLEYSFSSFDLSNPFS 1049
Cdd:pfam15376  961 GTDVFMNTGNCFAPGHRPLWRPLVSFGQNEQAiKGGGDGLNKGFSFIFHEDLLGSCGNFRGEEPGLEYPFSSFDLNNPFS 1040

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217352778 1050 QVLHVECSFEPEGIASFSPSFKPKSILCSDSDSEVFHPRICGVDRTQYRAIRISPRTHFRPISASELSPGGGSESEFESE 1129
Cdd:pfam15376 1041 QVLHVECSFEPEDIASFSPGFKPKSILCSDSENEVFHPRIYGINRTQYRAIRISPRTHFRPISASELSPGGGSESEAESE 1120

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217352778 1130 KDEANIPIPSQVDIFEDPQADLKPLEEDAEKEGHYYGKSELESGKFLPRLKKSGMEKSAQTSLDSQEESTGILSVGKQNQ 1209
Cdd:pfam15376 1121 KEEASIPVLSQVDVFDDPQADLKPLEEDAECEGPYYGKSELESGKFLPRLKKSGMEKSAQTSLDSQEGSGGLLPIAEQEI 1200

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217352778 1210 CLECSMNESLE-IDLESSEANCKIMAQCEEEI---NNFCGCKAGCQFPAYEDNPVSSGQLEEigkkekeerskilhhttt 1285
Cdd:pfam15376 1201 CLDCSIAASLEsISTEGSKTNCKIGEPQKEESsgeKEFCSCKAACQIPKYGKAYDFAGDLPE------------------ 1262

                         1290      1300      1310
                   ....*....|....*....|....*....|....*..
gi 2217352778 1286 iflrflFPVLNTDIQGMNRSQEKQTWWEKALYSPLFP 1322
Cdd:pfam15376 1263 ------FPLLNIDLQGGTGSQQEECWWQKALCSPLFP 1293
 
Name Accession Description Interval E-value
DUF4603 pfam15376
Domain of unknown function (DUF4603); This protein family is a domain of unknown function. In ...
 27-1322 0e+00

Domain of unknown function (DUF4603); This protein family is a domain of unknown function. In particular, this domain lies at the C-terminal end of a protein found in eukaryotes.


Pssm-ID: 464684  Cd Length: 1293  Bit Score: 2254.69  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217352778   27 VSEMSLLHALGPVQTWLGQELEKCGIDAMIYTRYVLSLLLHDSYDYDLQEQENDIFLGWEKGAYKKWGKSKKKCSDLTLE 106
Cdd:pfam15376    5 ASEMSLLQSLGPVQTWLGQELEKCGIDAMIYTRYVLSLLLHDSYDYDLQDQENDIFLGWEKGAGKKWGKSKKKGTDLSLE 84

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217352778  107 EMKKQAAVQCLRSASDESSGIETLVEELCSRLKDLQSKQ--EEKIHKKLEGSPSPEAELSPPAKDQVEMYYEAFPPLSEK 184
Cdd:pfam15376   85 EMKKQAAVQCLRSASDENSGIESLVEELCSKLKDLQNKQkeEKKINKKSEGSQSPERDESPSSKDQVEMYYEAFPPLSEK 164

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217352778  185 PVCLQEIMTVWNKSKVCSYSSSSSSSTAPPAStDTSSPKDCNSESEVTKERSSEVPTTVHEKT-QSKSKNEKENKFSNGT 263
Cdd:pfam15376  165 PVCLQEIMTVWNKAKACSYSSSSSSAAPQTST-DTSSPKDCNSEGEATKERNSEAPATTSERTqQRRSKKEKENRFHNGA 243

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217352778  264 IEEKPALY-KKQIRHKPEGKIRPRSWSSGSSEAGSSSSGNQGELKASMKYVKVRHKARE-IRNKKGRNGQSRLSLKHGEK 341
Cdd:pfam15376  244 AEEKSAVHsKKQVRHRSEGKYRPRSWSSGSSEAGSSSSGNQGDMKTSIKFVKVRHKSREaVRNKKGRNGQVKLALKVIDK 323

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217352778  342 AERNIHTGSSSSSSSGSVK-QLCKRGKRPLKEIgRKDPGSTEGKDLYMENRKDTEYKEEPLWYTEPIAEYFVPLSRKSKL 420
Cdd:pfam15376  324 EERRNAGGSSSSASGGSIKqQLCKKGKRPLKEI-RKDPGWVEGKESGGEARNKKEYMEEPLWYTEPITEYFVPLSRKSKL 402

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217352778  421 ETTYRNRQDTSDL--TSEAVEELSESVHGLCISNNNLHKTYLAAGTFIDGHFVEMPAVINEDIDLTGTSLCSLPEDNKYL 498
Cdd:pfam15376  403 ETKYRSKEDSPDGfaLSIDVEELSERVQGICIANSNIQRAYLAAGTFIDGHFVEMPAEGNEAADLNGTSSCPQPEDNKDL 482

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217352778  499 DDIHLSELTHFYEVDIDQSMLDPGASETMQgESRILNMIRQKSKENTDFEAECCIVLDGMELQGERAIWTDSTSSVGAEG 578
Cdd:pfam15376  483 DDEHLSEFTHFYEVDIYQSILDPSASDSVQ-ESRILNMIRQKSKEQRDFEAECCIVLDGLELQGESAIRADSTSASGAEG 561

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217352778  579 LFLQDLGNLAQFWECCS-SSSGDADGESFGGDSPVRLSPILDSTVLNSHLLAGNQE-LFSDINEGSGIN-SCFSVFEVQC 655
Cdd:pfam15376  562 FLMQDLENIAQVWECCSsSSSEDADGESFGGDSPIRLSPLLDSVSFNLSKLSGNQEeLFSEANEGSGLNsSCFSLFEVQY 641

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217352778  656 SNSVLPFSFETLNLGNENTDSS--ANMLGKTQSRLLIWTKNSAFEENEHCSNLSTRTCSPWSHSEETRSDNETLNIQFEE 733
Cdd:pfam15376  642 DSSTFPFPRDSLTLGHENTDSSscLNPLGNKQSRLLIWTKNSAFDETEHCSNLSTRTCSPWSHSEETRSDNEQFNAQAEE 721

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217352778  734 STQFNAEDINYVVPRVSSNYVDEELLDFLQDETCQQNSRTLGEIPTLVFKKTSKLESVCGIQLEQKtENKNFETTQVC-- 811
Cdd:pfam15376  722 SAQFGNEEINCVIPPLSSTYLEEELLDFLQEESCHQEEVSVSTASNQTFKKKSKLESVCGIALEQD-ESKQYESTGVFsd 800

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217352778  812 NESPHGDGYSSGVIKDIWTKMADTNSVATVEIERTDAELFSADVNNY-CCCLDAEAELETLQEPDKAVRRSEYHLWEGQK 890
Cdd:pfam15376  801 NSNQQGDDYSSGIIKDIWTAIGDRDSVITLGAEKMDEGLFSEEVNSYcCCCLDVEAKGEPLQEQKKAVQRSEYHLWEGQK 880

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217352778  891 ESLEKRAFASSELSNVDGGDYTTPSKPWDVAQDKENTFILGGVYGELKTFNSDGEWAVVPPSHTKGSLLQCAASDVVTIA 970
Cdd:pfam15376  881 ENLEEQALAKNELSKVDGGDYTTPSKPWDVNSDKESTFILGGVYGELKTFSSDGEWAVVPPSDSRGSLLQCAASDVVTIA 960

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217352778  971 GTDVFMTPGNSFAPGHRQLWKPFVSFEQNDQP-KSGENGLNKGFSFIFHEDLLGACGNFQVEDPGLEYSFSSFDLSNPFS 1049
Cdd:pfam15376  961 GTDVFMNTGNCFAPGHRPLWRPLVSFGQNEQAiKGGGDGLNKGFSFIFHEDLLGSCGNFRGEEPGLEYPFSSFDLNNPFS 1040

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217352778 1050 QVLHVECSFEPEGIASFSPSFKPKSILCSDSDSEVFHPRICGVDRTQYRAIRISPRTHFRPISASELSPGGGSESEFESE 1129
Cdd:pfam15376 1041 QVLHVECSFEPEDIASFSPGFKPKSILCSDSENEVFHPRIYGINRTQYRAIRISPRTHFRPISASELSPGGGSESEAESE 1120

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217352778 1130 KDEANIPIPSQVDIFEDPQADLKPLEEDAEKEGHYYGKSELESGKFLPRLKKSGMEKSAQTSLDSQEESTGILSVGKQNQ 1209
Cdd:pfam15376 1121 KEEASIPVLSQVDVFDDPQADLKPLEEDAECEGPYYGKSELESGKFLPRLKKSGMEKSAQTSLDSQEGSGGLLPIAEQEI 1200

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217352778 1210 CLECSMNESLE-IDLESSEANCKIMAQCEEEI---NNFCGCKAGCQFPAYEDNPVSSGQLEEigkkekeerskilhhttt 1285
Cdd:pfam15376 1201 CLDCSIAASLEsISTEGSKTNCKIGEPQKEESsgeKEFCSCKAACQIPKYGKAYDFAGDLPE------------------ 1262

                         1290      1300      1310
                   ....*....|....*....|....*....|....*..
gi 2217352778 1286 iflrflFPVLNTDIQGMNRSQEKQTWWEKALYSPLFP 1322
Cdd:pfam15376 1263 ------FPLLNIDLQGGTGSQQEECWWQKALCSPLFP 1293
 
Name Accession Description Interval E-value
DUF4603 pfam15376
Domain of unknown function (DUF4603); This protein family is a domain of unknown function. In ...
 27-1322 0e+00

Domain of unknown function (DUF4603); This protein family is a domain of unknown function. In particular, this domain lies at the C-terminal end of a protein found in eukaryotes.


Pssm-ID: 464684  Cd Length: 1293  Bit Score: 2254.69  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217352778   27 VSEMSLLHALGPVQTWLGQELEKCGIDAMIYTRYVLSLLLHDSYDYDLQEQENDIFLGWEKGAYKKWGKSKKKCSDLTLE 106
Cdd:pfam15376    5 ASEMSLLQSLGPVQTWLGQELEKCGIDAMIYTRYVLSLLLHDSYDYDLQDQENDIFLGWEKGAGKKWGKSKKKGTDLSLE 84

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217352778  107 EMKKQAAVQCLRSASDESSGIETLVEELCSRLKDLQSKQ--EEKIHKKLEGSPSPEAELSPPAKDQVEMYYEAFPPLSEK 184
Cdd:pfam15376   85 EMKKQAAVQCLRSASDENSGIESLVEELCSKLKDLQNKQkeEKKINKKSEGSQSPERDESPSSKDQVEMYYEAFPPLSEK 164

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217352778  185 PVCLQEIMTVWNKSKVCSYSSSSSSSTAPPAStDTSSPKDCNSESEVTKERSSEVPTTVHEKT-QSKSKNEKENKFSNGT 263
Cdd:pfam15376  165 PVCLQEIMTVWNKAKACSYSSSSSSAAPQTST-DTSSPKDCNSEGEATKERNSEAPATTSERTqQRRSKKEKENRFHNGA 243

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217352778  264 IEEKPALY-KKQIRHKPEGKIRPRSWSSGSSEAGSSSSGNQGELKASMKYVKVRHKARE-IRNKKGRNGQSRLSLKHGEK 341
Cdd:pfam15376  244 AEEKSAVHsKKQVRHRSEGKYRPRSWSSGSSEAGSSSSGNQGDMKTSIKFVKVRHKSREaVRNKKGRNGQVKLALKVIDK 323

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217352778  342 AERNIHTGSSSSSSSGSVK-QLCKRGKRPLKEIgRKDPGSTEGKDLYMENRKDTEYKEEPLWYTEPIAEYFVPLSRKSKL 420
Cdd:pfam15376  324 EERRNAGGSSSSASGGSIKqQLCKKGKRPLKEI-RKDPGWVEGKESGGEARNKKEYMEEPLWYTEPITEYFVPLSRKSKL 402

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217352778  421 ETTYRNRQDTSDL--TSEAVEELSESVHGLCISNNNLHKTYLAAGTFIDGHFVEMPAVINEDIDLTGTSLCSLPEDNKYL 498
Cdd:pfam15376  403 ETKYRSKEDSPDGfaLSIDVEELSERVQGICIANSNIQRAYLAAGTFIDGHFVEMPAEGNEAADLNGTSSCPQPEDNKDL 482

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217352778  499 DDIHLSELTHFYEVDIDQSMLDPGASETMQgESRILNMIRQKSKENTDFEAECCIVLDGMELQGERAIWTDSTSSVGAEG 578
Cdd:pfam15376  483 DDEHLSEFTHFYEVDIYQSILDPSASDSVQ-ESRILNMIRQKSKEQRDFEAECCIVLDGLELQGESAIRADSTSASGAEG 561

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217352778  579 LFLQDLGNLAQFWECCS-SSSGDADGESFGGDSPVRLSPILDSTVLNSHLLAGNQE-LFSDINEGSGIN-SCFSVFEVQC 655
Cdd:pfam15376  562 FLMQDLENIAQVWECCSsSSSEDADGESFGGDSPIRLSPLLDSVSFNLSKLSGNQEeLFSEANEGSGLNsSCFSLFEVQY 641

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217352778  656 SNSVLPFSFETLNLGNENTDSS--ANMLGKTQSRLLIWTKNSAFEENEHCSNLSTRTCSPWSHSEETRSDNETLNIQFEE 733
Cdd:pfam15376  642 DSSTFPFPRDSLTLGHENTDSSscLNPLGNKQSRLLIWTKNSAFDETEHCSNLSTRTCSPWSHSEETRSDNEQFNAQAEE 721

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217352778  734 STQFNAEDINYVVPRVSSNYVDEELLDFLQDETCQQNSRTLGEIPTLVFKKTSKLESVCGIQLEQKtENKNFETTQVC-- 811
Cdd:pfam15376  722 SAQFGNEEINCVIPPLSSTYLEEELLDFLQEESCHQEEVSVSTASNQTFKKKSKLESVCGIALEQD-ESKQYESTGVFsd 800

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217352778  812 NESPHGDGYSSGVIKDIWTKMADTNSVATVEIERTDAELFSADVNNY-CCCLDAEAELETLQEPDKAVRRSEYHLWEGQK 890
Cdd:pfam15376  801 NSNQQGDDYSSGIIKDIWTAIGDRDSVITLGAEKMDEGLFSEEVNSYcCCCLDVEAKGEPLQEQKKAVQRSEYHLWEGQK 880

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217352778  891 ESLEKRAFASSELSNVDGGDYTTPSKPWDVAQDKENTFILGGVYGELKTFNSDGEWAVVPPSHTKGSLLQCAASDVVTIA 970
Cdd:pfam15376  881 ENLEEQALAKNELSKVDGGDYTTPSKPWDVNSDKESTFILGGVYGELKTFSSDGEWAVVPPSDSRGSLLQCAASDVVTIA 960

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217352778  971 GTDVFMTPGNSFAPGHRQLWKPFVSFEQNDQP-KSGENGLNKGFSFIFHEDLLGACGNFQVEDPGLEYSFSSFDLSNPFS 1049
Cdd:pfam15376  961 GTDVFMNTGNCFAPGHRPLWRPLVSFGQNEQAiKGGGDGLNKGFSFIFHEDLLGSCGNFRGEEPGLEYPFSSFDLNNPFS 1040

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217352778 1050 QVLHVECSFEPEGIASFSPSFKPKSILCSDSDSEVFHPRICGVDRTQYRAIRISPRTHFRPISASELSPGGGSESEFESE 1129
Cdd:pfam15376 1041 QVLHVECSFEPEDIASFSPGFKPKSILCSDSENEVFHPRIYGINRTQYRAIRISPRTHFRPISASELSPGGGSESEAESE 1120

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217352778 1130 KDEANIPIPSQVDIFEDPQADLKPLEEDAEKEGHYYGKSELESGKFLPRLKKSGMEKSAQTSLDSQEESTGILSVGKQNQ 1209
Cdd:pfam15376 1121 KEEASIPVLSQVDVFDDPQADLKPLEEDAECEGPYYGKSELESGKFLPRLKKSGMEKSAQTSLDSQEGSGGLLPIAEQEI 1200

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217352778 1210 CLECSMNESLE-IDLESSEANCKIMAQCEEEI---NNFCGCKAGCQFPAYEDNPVSSGQLEEigkkekeerskilhhttt 1285
Cdd:pfam15376 1201 CLDCSIAASLEsISTEGSKTNCKIGEPQKEESsgeKEFCSCKAACQIPKYGKAYDFAGDLPE------------------ 1262

                         1290      1300      1310
                   ....*....|....*....|....*....|....*..
gi 2217352778 1286 iflrflFPVLNTDIQGMNRSQEKQTWWEKALYSPLFP 1322
Cdd:pfam15376 1263 ------FPLLNIDLQGGTGSQQEECWWQKALCSPLFP 1293
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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