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Conserved domains on  [gi|2047972720|ref|XP_041809348|]
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ragulator complex protein LAMTOR3 [Chelmon rostratus]

Protein Classification

MAPKK1_Int domain-containing protein( domain architecture ID 10556417)

MAPKK1_Int domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
MAPKK1_Int pfam08923
Mitogen-activated protein kinase kinase 1 interacting; Mitogen-activated protein kinase kinase ...
 3-121 3.29e-68

Mitogen-activated protein kinase kinase 1 interacting; Mitogen-activated protein kinase kinase 1 interacting protein is a small subcellular adaptor protein required for MAPK signaling and ERK1/2 activation. The overall topology of this domain has a central five-stranded beta-sheet sandwiched between a two alpha-helix and a one alpha-helix layer.


:

Pssm-ID: 462635  Cd Length: 119  Bit Score: 200.65  E-value: 3.29e-68
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2047972720   3 DDLKRYLYKQLQSVEGLHAIVVTDRDGVPVIKVANDNAPVHALRPGFLSTFALATDQGSKLGLSKNKSIICYYNTYQIVQ 82
Cdd:pfam08923   1 DDVKRFLYKKLSSVDGLHAIFITDRDGVPLLKVGDDSSPDSALRPSFISTFATATDQASKLGLGKNKSIISYYEDYQVVQ 80

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 2047972720  83 FNRLPLVISFIASSNANTGLIMSLEKELAPLIEELRQVV 121
Cdd:pfam08923  81 FNKLPLILSFIASTNCNTGLILSLEQELFPLLNELKSVV 119
 
Name Accession Description Interval E-value
MAPKK1_Int pfam08923
Mitogen-activated protein kinase kinase 1 interacting; Mitogen-activated protein kinase kinase ...
 3-121 3.29e-68

Mitogen-activated protein kinase kinase 1 interacting; Mitogen-activated protein kinase kinase 1 interacting protein is a small subcellular adaptor protein required for MAPK signaling and ERK1/2 activation. The overall topology of this domain has a central five-stranded beta-sheet sandwiched between a two alpha-helix and a one alpha-helix layer.


Pssm-ID: 462635  Cd Length: 119  Bit Score: 200.65  E-value: 3.29e-68
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2047972720   3 DDLKRYLYKQLQSVEGLHAIVVTDRDGVPVIKVANDNAPVHALRPGFLSTFALATDQGSKLGLSKNKSIICYYNTYQIVQ 82
Cdd:pfam08923   1 DDVKRFLYKKLSSVDGLHAIFITDRDGVPLLKVGDDSSPDSALRPSFISTFATATDQASKLGLGKNKSIISYYEDYQVVQ 80

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 2047972720  83 FNRLPLVISFIASSNANTGLIMSLEKELAPLIEELRQVV 121
Cdd:pfam08923  81 FNKLPLILSFIASTNCNTGLILSLEQELFPLLNELKSVV 119
 
Name Accession Description Interval E-value
MAPKK1_Int pfam08923
Mitogen-activated protein kinase kinase 1 interacting; Mitogen-activated protein kinase kinase ...
 3-121 3.29e-68

Mitogen-activated protein kinase kinase 1 interacting; Mitogen-activated protein kinase kinase 1 interacting protein is a small subcellular adaptor protein required for MAPK signaling and ERK1/2 activation. The overall topology of this domain has a central five-stranded beta-sheet sandwiched between a two alpha-helix and a one alpha-helix layer.


Pssm-ID: 462635  Cd Length: 119  Bit Score: 200.65  E-value: 3.29e-68
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2047972720   3 DDLKRYLYKQLQSVEGLHAIVVTDRDGVPVIKVANDNAPVHALRPGFLSTFALATDQGSKLGLSKNKSIICYYNTYQIVQ 82
Cdd:pfam08923   1 DDVKRFLYKKLSSVDGLHAIFITDRDGVPLLKVGDDSSPDSALRPSFISTFATATDQASKLGLGKNKSIISYYEDYQVVQ 80

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 2047972720  83 FNRLPLVISFIASSNANTGLIMSLEKELAPLIEELRQVV 121
Cdd:pfam08923  81 FNKLPLILSFIASTNCNTGLILSLEQELFPLLNELKSVV 119
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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