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Conserved domains on  [gi|1958776745|ref|XP_038966001|]
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rootletin isoform X1 [Rattus norvegicus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Rootletin pfam15035
Ciliary rootlet component, centrosome cohesion;
158-334 1.10e-49

Ciliary rootlet component, centrosome cohesion;


:

Pssm-ID: 464459 [Multi-domain]  Cd Length: 190  Bit Score: 175.23  E-value: 1.10e-49
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  158 RRKLQAYQEGQQRQAQLVQRLQAKILQYKKQCSEMEKQLLERSTELEQQRL-------------RDTEHSQDLDRALLRL 224
Cdd:pfam15035    1 RRKLQAYQEAQQRQAQLVQKLQAKVLQYKKRCSELEQQLLEKTSELEKTELllrkltleprlqrLEREHSADLEEALIRL 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  225 EEEQQRSASLAQVNDMLREQLDQANLANQTLSEDICKVTSDWTRSCKELEQREATWRREEESFNAYFSSEHSRLLLLWRQ 304
Cdd:pfam15035   81 EEERQRSESLSQVNSLLREQLEQASRANEALREDLQKLTNDWERAREELEQKESEWRKEEEAFNEYLSSEHSRLLSLWRE 160

                          170       180       190
                   ....*....|....*....|....*....|
gi 1958776745  305 VMGLRRMASEVKMGTERDLLQLGGELVRTS 334
Cdd:pfam15035  161 VVAVRRQFTELKTATERDLSELKTEFSRTS 190
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 532-1072 1.16e-26

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 119.27  E-value: 1.16e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  532 KRQLQVQDMRGRYEASQDLLGSVRKQLSDSEGERRGLEEQLQRLRDQTATSVQAQEDAQREAQRLRSANEILSREKGNLS 611
Cdd:COG1196    222 LKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLE 301

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  612 HSLQVAQQQAEDLRQELEKLQAAQEELRRQHTQLEDQQEDTVQEGARARRELERSHRQLEQLEVKRSGLTKELVEVREAL 691
Cdd:COG1196    302 QDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEEL 381

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  692 SCAVLQRDVLQTEKAEVAEALTKAEAGRAQLELSVTKLRAEEASLRDSLSKMSALNESLAQDKLELNRLIAQLEEEKAAL 771
Cdd:COG1196    382 EELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEAL 461

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  772 LGRQQQAEHATSLAVEKQERLEQLRLEQEVERQGLEGSLCVAEQAREALGQQILVLRSERSHLQEQVAQLSRQLNGRDQE 851
Cdd:COG1196    462 LELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALE 541

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  852 LDQALRESQRQVEALERAAREKEAMAKERAGLAVQLAAAEREGRTLSEETIRLRLEKEALESSLFDVQRQLAQLEARREQ 931
Cdd:COG1196    542 AALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDT 621

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  932 LEADS--QALLLAKETLTGELAGLRQQVTATEEKAALDKELMTQKLVQAERETQASLREQRAAHEEDLQRLQREKEAAWR 1009
Cdd:COG1196    622 LLGRTlvAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLA 701

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1958776745 1010 ELQAERAQLQGQLQQEREELLARMEAEKEELSEEIAALQQERDEGLLLAESEKQQALSLKESE 1072
Cdd:COG1196    702 EEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEE 764
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1118-1851 5.05e-26

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 117.46  E-value: 5.05e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1118 ELRDLRAQLEEATAA-HAQQVKELQEQTGNLGRQREACMREAEELRTQLRLLEDTRDGLRRELLEAQRKVRDSQDSSEAH 1196
Cdd:TIGR02168  214 RYKELKAELRELELAlLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYAL 293

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1197 RQEASELRRSLSEGTKEREALRRSNEELRTAVKKAESERISLKLANEDKEQKLALLEEARMSVAKEAGELRASLQEVERS 1276
Cdd:TIGR02168  294 ANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESR 373

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1277 RLEARRELQELRR-------QMKTLDSDNGRLGRELADLQSRLA-LGERTEKESRREVLGLRQKVLKGESSLEALKQELQ 1348
Cdd:TIGR02168  374 LEELEEQLETLRSkvaqlelQIASLNNEIERLEARLERLEDRRErLQQEIEELLKKLEEAELKELQAELEELEEELEELQ 453

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1349 GSQRKLQEQEAEFRARERGLLGSLEEARGAEKKLLDSARSLELRLEGVRAETSELGLRLSAAEGRAQGLEV--ELARVEA 1426
Cdd:TIGR02168  454 EELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVlsELISVDE 533

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1427 QRRVA-EAQLGG-LRSALRRGLGLGRVSSSPAREAPAGGSG----DGLSSPSPLEYSPRSQPPSPGPVASPAPPDLDPEA 1500
Cdd:TIGR02168  534 GYEAAiEAALGGrLQAVVVENLNAAKKAIAFLKQNELGRVTflplDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPK 613

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1501 VRDALRDFL------QELRSA-----------------------------------------QRERDELRVQTSTLSQQL 1533
Cdd:TIGR02168  614 LRKALSYLLggvlvvDDLDNAlelakklrpgyrivtldgdlvrpggvitggsaktnssilerRREIEELEEKIEELEEKI 693

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1534 AEMEAERDHAASRAKQLQKAVAESEEAWRSADRRLSGAQAELAlqeesvrRSRRECRATLDQMAVLERSLQATESELRAS 1613
Cdd:TIGR02168  694 AELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLA-------RLEAEVEQLEERIAQLSKELTELEAEIEEL 766

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1614 QEKVNKMKATEVKLESDKRRLKEVLDASESRSIKLELQRRALEGELQRSRLGLGDREAHAQALQDRVDSLQRQVADSEVK 1693
Cdd:TIGR02168  767 EERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQ 846

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1694 AGTLQLTVERLSGALAKVEESEGTLRSKVQSLTDALAQSSASLTSsqdknlyLQKALSTCEHDRQVLQERLDAARQALSE 1773
Cdd:TIGR02168  847 IEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALAL-------LRSELEELSEELRELESKRSELRRELEE 919

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1958776745 1774 ARRQSSSLGEQVQTLRGELANLeLQRGDAEGQLQqlqqvlrqrqegEAVALRSVQKLQEERRLLQERLGSLQRALAQL 1851
Cdd:TIGR02168  920 LREKLAQLELRLEGLEVRIDNL-QERLSEEYSLT------------LEEAEALENKIEDDEEEARRRLKRLENKIKEL 984
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1721-1984 2.44e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 59.57  E-value: 2.44e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1721 KVQSLTDALAQSSASLTSSQDKNLYLQKALSTCEHDRQVLQ-ERLDA-----------ARQALSEARRQSSSLGEQVQTL 1788
Cdd:COG1196    214 RYRELKEELKELEAELLLLKLRELEAELEELEAELEELEAElEELEAelaeleaeleeLRLELEELELELEEAQAEEYEL 293

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1789 RGELANLELQRGDAEGQLQQLQQVLRQRQEGEAVALRSVQKLQEERRLLQERLGSLQRALAQLEAEKRELERSALQLDKD 1868
Cdd:COG1196    294 LAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAE 373

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1869 RVALRKTLDKVEREKLRSHEDTLRLNAERGRLDRTLTGAELDLAEAQQQIQHLEAQVVEVLER--NHSPVQVEADEQHLE 1946
Cdd:COG1196    374 LAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEeeEEEEALEEAAEEEAE 453

                          250       260       270
                   ....*....|....*....|....*....|....*...
gi 1958776745 1947 LQQEVERLRSAQVRTERTLEARERAHRQRVSGLEEQVQ 1984
Cdd:COG1196    454 LEEEEEALLELLAELLEEAALLEAALAELLEELAEAAA 491
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 73-480 4.43e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 51.86  E-value: 4.43e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745   73 PEMASLLSLQEENQLLQQELSRVEDLLAQSRAERDELAIKYNAINERLEQAVRLETGELEAQEprglvrQSVELRRQLQE 152
Cdd:COG1196    306 RLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALL------EAEAELAEAEE 379

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  153 EQASYRRKLQAYQEGQQRQAQLVQRLQAKILQYKKQCSEMEKQLLERSTELEQQRLRDTEHSQDLDRALLRLEEEQQRSA 232
Cdd:COG1196    380 ELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEE 459

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  233 SLAQVNDMLREQLDQANLANQTLSEDICKVTSdwtrscKELEQREATWRREEESFNAYFSSEHSRLLLLWRQVMGLRRMA 312
Cdd:COG1196    460 ALLELLAELLEEAALLEAALAELLEELAEAAA------RLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVE 533

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  313 SEVKMGTERDLLQLGGELVRTSRavqEVGLGLSASLQRAESRAEAALEKQKLLQAQLEEQLRAKLLREKDLAQLQVQSDL 392
Cdd:COG1196    534 AAYEAALEAALAAALQNIVVEDD---EVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLRE 610

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  393 DKADLSARVTELALSVEHLQNQNTEKDQVNRTLSDKLEALESLRLQEQTTLDTEDGEGLQQTLRDLAQAALSDTESGVQL 472
Cdd:COG1196    611 ADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAE 690


                   ....*...
gi 1958776745  473 SNSERTAD 480
Cdd:COG1196    691 EELELEEA 698
 
Name Accession Description Interval E-value
Rootletin pfam15035
Ciliary rootlet component, centrosome cohesion;
158-334 1.10e-49

Ciliary rootlet component, centrosome cohesion;


Pssm-ID: 464459 [Multi-domain]  Cd Length: 190  Bit Score: 175.23  E-value: 1.10e-49
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  158 RRKLQAYQEGQQRQAQLVQRLQAKILQYKKQCSEMEKQLLERSTELEQQRL-------------RDTEHSQDLDRALLRL 224
Cdd:pfam15035    1 RRKLQAYQEAQQRQAQLVQKLQAKVLQYKKRCSELEQQLLEKTSELEKTELllrkltleprlqrLEREHSADLEEALIRL 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  225 EEEQQRSASLAQVNDMLREQLDQANLANQTLSEDICKVTSDWTRSCKELEQREATWRREEESFNAYFSSEHSRLLLLWRQ 304
Cdd:pfam15035   81 EEERQRSESLSQVNSLLREQLEQASRANEALREDLQKLTNDWERAREELEQKESEWRKEEEAFNEYLSSEHSRLLSLWRE 160

                          170       180       190
                   ....*....|....*....|....*....|
gi 1958776745  305 VMGLRRMASEVKMGTERDLLQLGGELVRTS 334
Cdd:pfam15035  161 VVAVRRQFTELKTATERDLSELKTEFSRTS 190
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 532-1072 1.16e-26

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 119.27  E-value: 1.16e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  532 KRQLQVQDMRGRYEASQDLLGSVRKQLSDSEGERRGLEEQLQRLRDQTATSVQAQEDAQREAQRLRSANEILSREKGNLS 611
Cdd:COG1196    222 LKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLE 301

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  612 HSLQVAQQQAEDLRQELEKLQAAQEELRRQHTQLEDQQEDTVQEGARARRELERSHRQLEQLEVKRSGLTKELVEVREAL 691
Cdd:COG1196    302 QDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEEL 381

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  692 SCAVLQRDVLQTEKAEVAEALTKAEAGRAQLELSVTKLRAEEASLRDSLSKMSALNESLAQDKLELNRLIAQLEEEKAAL 771
Cdd:COG1196    382 EELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEAL 461

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  772 LGRQQQAEHATSLAVEKQERLEQLRLEQEVERQGLEGSLCVAEQAREALGQQILVLRSERSHLQEQVAQLSRQLNGRDQE 851
Cdd:COG1196    462 LELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALE 541

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  852 LDQALRESQRQVEALERAAREKEAMAKERAGLAVQLAAAEREGRTLSEETIRLRLEKEALESSLFDVQRQLAQLEARREQ 931
Cdd:COG1196    542 AALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDT 621

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  932 LEADS--QALLLAKETLTGELAGLRQQVTATEEKAALDKELMTQKLVQAERETQASLREQRAAHEEDLQRLQREKEAAWR 1009
Cdd:COG1196    622 LLGRTlvAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLA 701

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1958776745 1010 ELQAERAQLQGQLQQEREELLARMEAEKEELSEEIAALQQERDEGLLLAESEKQQALSLKESE 1072
Cdd:COG1196    702 EEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEE 764
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1118-1851 5.05e-26

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 117.46  E-value: 5.05e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1118 ELRDLRAQLEEATAA-HAQQVKELQEQTGNLGRQREACMREAEELRTQLRLLEDTRDGLRRELLEAQRKVRDSQDSSEAH 1196
Cdd:TIGR02168  214 RYKELKAELRELELAlLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYAL 293

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1197 RQEASELRRSLSEGTKEREALRRSNEELRTAVKKAESERISLKLANEDKEQKLALLEEARMSVAKEAGELRASLQEVERS 1276
Cdd:TIGR02168  294 ANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESR 373

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1277 RLEARRELQELRR-------QMKTLDSDNGRLGRELADLQSRLA-LGERTEKESRREVLGLRQKVLKGESSLEALKQELQ 1348
Cdd:TIGR02168  374 LEELEEQLETLRSkvaqlelQIASLNNEIERLEARLERLEDRRErLQQEIEELLKKLEEAELKELQAELEELEEELEELQ 453

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1349 GSQRKLQEQEAEFRARERGLLGSLEEARGAEKKLLDSARSLELRLEGVRAETSELGLRLSAAEGRAQGLEV--ELARVEA 1426
Cdd:TIGR02168  454 EELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVlsELISVDE 533

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1427 QRRVA-EAQLGG-LRSALRRGLGLGRVSSSPAREAPAGGSG----DGLSSPSPLEYSPRSQPPSPGPVASPAPPDLDPEA 1500
Cdd:TIGR02168  534 GYEAAiEAALGGrLQAVVVENLNAAKKAIAFLKQNELGRVTflplDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPK 613

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1501 VRDALRDFL------QELRSA-----------------------------------------QRERDELRVQTSTLSQQL 1533
Cdd:TIGR02168  614 LRKALSYLLggvlvvDDLDNAlelakklrpgyrivtldgdlvrpggvitggsaktnssilerRREIEELEEKIEELEEKI 693

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1534 AEMEAERDHAASRAKQLQKAVAESEEAWRSADRRLSGAQAELAlqeesvrRSRRECRATLDQMAVLERSLQATESELRAS 1613
Cdd:TIGR02168  694 AELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLA-------RLEAEVEQLEERIAQLSKELTELEAEIEEL 766

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1614 QEKVNKMKATEVKLESDKRRLKEVLDASESRSIKLELQRRALEGELQRSRLGLGDREAHAQALQDRVDSLQRQVADSEVK 1693
Cdd:TIGR02168  767 EERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQ 846

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1694 AGTLQLTVERLSGALAKVEESEGTLRSKVQSLTDALAQSSASLTSsqdknlyLQKALSTCEHDRQVLQERLDAARQALSE 1773
Cdd:TIGR02168  847 IEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALAL-------LRSELEELSEELRELESKRSELRRELEE 919

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1958776745 1774 ARRQSSSLGEQVQTLRGELANLeLQRGDAEGQLQqlqqvlrqrqegEAVALRSVQKLQEERRLLQERLGSLQRALAQL 1851
Cdd:TIGR02168  920 LREKLAQLELRLEGLEVRIDNL-QERLSEEYSLT------------LEEAEALENKIEDDEEEARRRLKRLENKIKEL 984
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 535-1356 7.39e-26

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 117.08  E-value: 7.39e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  535 LQVQDMRGRYEASQDLLGSVRKQLSDSEGERRGLEEQLQRLRDQTATSVQAQEDAQREAQRLRSANEILSREKGNLSHSL 614
Cdd:TIGR02168  232 LRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERL 311

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  615 QVAQQQAEDLRQELEKLQAAQEELRRQHTQLEDQQEDTVQEGARARRELERSHRQLEQLEVKRSGLTKELVEVREALSCA 694
Cdd:TIGR02168  312 ANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQL 391

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  695 VLQRDVLQTEkaevaeaLTKAEAGRAQLELSVTKLRAEEASLRDSLS--KMSALNESLAQDKLELNRLIAQLEEEKAALL 772
Cdd:TIGR02168  392 ELQIASLNNE-------IERLEARLERLEDRRERLQQEIEELLKKLEeaELKELQAELEELEEELEELQEELERLEEALE 464

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  773 GRQQQAEHATSLAVEKQERLEQLRLEQEVERQGLEGSLCVAEQAREALGQQilvlrSERSHLQEQVAQLSRQLNGRDQEL 852
Cdd:TIGR02168  465 ELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQ-----SGLSGILGVLSELISVDEGYEAAI 539

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  853 DQALRESQRQ--VEALERAAREKEAMAKERAGLAVQLAAAEREGRTLSEETIRLRLEKEalesslfDVQRQLAQLEARRE 930
Cdd:TIGR02168  540 EAALGGRLQAvvVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIE-------GFLGVAKDLVKFDP 612

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  931 QLEADSQALL---LAKETLTGELAgLRQQVTATEEKAALDKELMTQKLVQAeretqaslreqRAAHEEDLQRLQREKEAA 1007
Cdd:TIGR02168  613 KLRKALSYLLggvLVVDDLDNALE-LAKKLRPGYRIVTLDGDLVRPGGVIT-----------GGSAKTNSSILERRREIE 680

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1008 wrELQAERAQLQGQLQQEREELlarmeaekeelseeiAALQQERDeglllaesEKQQALSLKESEKTALSEKLMGTRHSL 1087
Cdd:TIGR02168  681 --ELEEKIEELEEKIAELEKAL---------------AELRKELE--------ELEEELEQLRKELEELSRQISALRKDL 735

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1088 AAISLEmERQKRDAQSRQEQDRNTVNALTSELRDLRAQLEEATAAHAQQVKELQEQTGNLGRQREACMREAEELRTQLRL 1167
Cdd:TIGR02168  736 ARLEAE-VEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTL 814

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1168 LEDTRDGLRRELLEAQRKVRDSQDSSEAHRQEASELRRSLSEGTKEREALRRSNEELRTAVKKAESERislklanedkeq 1247
Cdd:TIGR02168  815 LNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNER------------ 882

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1248 klALLEEARMSVAKEAGELRASLQEVERSRLEARRELQELRRQMKTLDSDNGRLGRELADLQSRLALGERTEKEsrrevl 1327
Cdd:TIGR02168  883 --ASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLE------ 954

                          810       820
                   ....*....|....*....|....*....
gi 1958776745 1328 GLRQKVLKGESSLEALKQELQGSQRKLQE 1356
Cdd:TIGR02168  955 EAEALENKIEDDEEEARRRLKRLENKIKE 983
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 755-1427 8.85e-23

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 106.68  E-value: 8.85e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  755 LELNRLIAQLEEEKAALLGRQQQAEHATSLAVEKQERLEQLRLEQEVerqgLEGSLCVAEQAREALGQQILVLRSERSHL 834
Cdd:TIGR02168  232 LRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSE----LEEEIEELQKELYALANEISRLEQQKQIL 307

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  835 QEQVAQLSRQLNGRDQELDQALRESQRQVEALERAAREKEAMAKERAGLAVQLAAAEREGRTLSEETIRLRLEKEALESS 914
Cdd:TIGR02168  308 RERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSK 387

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  915 LFDVQRQLAQLEARREQLEADsqalllaKETLTGELAGLRQQVTATEEKAALDKELMTQKLVQAERETQASLREQRAAHE 994
Cdd:TIGR02168  388 VAQLELQIASLNNEIERLEAR-------LERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLE 460

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  995 EDLQRLQREKEAAWRELQAERAQLQgQLQQeREELLARMEAEKEELSEEIAALQQERdEGLLLAESEKQQALSLKESEKT 1074
Cdd:TIGR02168  461 EALEELREELEEAEQALDAAERELA-QLQA-RLDSLERLQENLEGFSEGVKALLKNQ-SGLSGILGVLSELISVDEGYEA 537

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1075 ALSEKLMGTRHSLAAISLEMERQKRDAQSRQEQDRNTVNALTS-------------------------ELRDLRAQLEEA 1129
Cdd:TIGR02168  538 AIEAALGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSikgteiqgndreilkniegflgvakDLVKFDPKLRKA 617

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1130 --------------TAAHAQQVKELQEQT------------------------GNLGRQRE--ACMREAEELRTQLRLLE 1169
Cdd:TIGR02168  618 lsyllggvlvvddlDNALELAKKLRPGYRivtldgdlvrpggvitggsaktnsSILERRREieELEEKIEELEEKIAELE 697

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1170 DTRDGLRRELLEAQRKVRDSQDSSEAHRQEASELRRSLSEGTKEREALRRSNEELRTAVKKAESERISLKLANEDKEQKL 1249
Cdd:TIGR02168  698 KALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEEL 777

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1250 ALLEEARMSVAKEAGELRASLQEVERSRLEARRELQELRRqmktldsDNGRLGRELADLQSRLALGERTEKESRREVLGL 1329
Cdd:TIGR02168  778 AEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNE-------EAANLRERLESLERRIAATERRLEDLEEQIEEL 850

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1330 RQKVLKGESSLEALKQELQGSQRKLQEQEAEFRARERGllgsLEEARGAEKKLLDSARSLELRLEGVRAETSELGLRLSA 1409
Cdd:TIGR02168  851 SEDIESLAAEIEELEELIEELESELEALLNERASLEEA----LALLRSELEELSEELRELESKRSELRRELEELREKLAQ 926

                          730
                   ....*....|....*...
gi 1958776745 1410 AEGRAQGLEVELARVEAQ 1427
Cdd:TIGR02168  927 LELRLEGLEVRIDNLQER 944
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1095-1656 1.48e-22

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 105.79  E-value: 1.48e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1095 ERQKRDAQSRQEqdrntvnaLTSELRDLRAQLEEATAAHAQ-QVKELQEQTGNLGRQREACMREAEELRTQLRLLEDTRD 1173
Cdd:COG1196    206 ERQAEKAERYRE--------LKEELKELEAELLLLKLRELEaELEELEAELEELEAELEELEAELAELEAELEELRLELE 277

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1174 GLRRELLEAQRKVRDSQDSSEAHRQEASELRRSLSEGTKEREALRRSNEELRTAVKKAESERISLKLANEDKEQKLALLE 1253
Cdd:COG1196    278 ELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAE 357

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1254 EARMSVAKEAGELRASLQEVERSRLEARRELQELRRQMKTLDSDNGRLGRELADLQSR----------LALGERTEKESR 1323
Cdd:COG1196    358 AELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERlerleeeleeLEEALAELEEEE 437

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1324 REVLGLRQKVLKGESSLEALKQELQGSQRKLQEQEAEFRARERGLLGSLEEARGAEKKLLDSARSLELRLEGVRAETSEL 1403
Cdd:COG1196    438 EEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLA 517

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1404 GLRLSAAEGR---------AQGLEVELARVEAQRRVAEAQLGGLRSALRRGLGLGRVSSSPAREAPAGGSGDGLSSPSPL 1474
Cdd:COG1196    518 GLRGLAGAVAvligveaayEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAI 597

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1475 EYSPRSQPPSPGPVASPAPPDLDPEAVRDAL-RDFLQELRSAQRERDELRVQTSTLSQQLAEMEAERDHAASRAKQLQKA 1553
Cdd:COG1196    598 GAAVDLVASDLREADARYYVLGDTLLGRTLVaARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEA 677

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1554 VAESEEAWRSADRRLSGAQAELALQEESVRRSRRECRATLDQMAVLERSLQATESELRASQEKVNKMKATEVKLESDKRR 1633
Cdd:COG1196    678 EAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELP 757

                          570       580
                   ....*....|....*....|...
gi 1958776745 1634 LKEVLDASESRSIKLELQRRALE 1656
Cdd:COG1196    758 EPPDLEELERELERLEREIEALG 780
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 813-1404 8.39e-22

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 103.48  E-value: 8.39e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  813 AEQAREALGQQILVLRSERSHLQEQVAQLSRQLNGRDQELDQALRESQRQVEALERAAREKEAMAKERAGLAVQLAAAER 892
Cdd:COG1196    209 AEKAERYRELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQA 288

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  893 EGRTLSEETIRLRLEKEALESSLFDVQRQLAQLEARREQLEADSQALLLAKETLTGELAGLRQQVTATEEKAALDKElmt 972
Cdd:COG1196    289 EEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEE--- 365

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  973 qKLVQAERETQASLREQRAAHEEDLQRLQREKEAAWRELQAERAqlqgqlQQEREELLARMEAEKEELSEEIAALQQERD 1052
Cdd:COG1196    366 -ALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEA------EEALLERLERLEEELEELEEALAELEEEEE 438

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1053 EGLLLAESEKQQALSLKESEKTALSEklmgtRHSLAAISLEMERQKRDAQSRQEQDRNTVNALTSELRDLRAQLEEATAA 1132
Cdd:COG1196    439 EEEEALEEAAEEEAELEEEEEALLEL-----LAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAA 513

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1133 HAQQVKELQEQTGNLGRQREACMREAEELRTQLRLLEDtrdglRRELLEAQRKVRDSQDSSEAHRQEASELRRSLSEGTK 1212
Cdd:COG1196    514 LLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNI-----VVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAAL 588

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1213 EREALRRSNEELRTAVKKAESERISLKLANEDKEQKLALLEEARMSVAKEAGELRASLQEVERSRLEARRELQELRRQMK 1292
Cdd:COG1196    589 AAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRR 668

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1293 TLDSDNGRLGRELADLQSRLALGERTEKESRREVLGLRQKVLKGESSLEALKQELQGSQRKLQEQEAEFRARERGLLGSL 1372
Cdd:COG1196    669 ELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELL 748

                          570       580       590
                   ....*....|....*....|....*....|..
gi 1958776745 1373 EEARGAEKKLLDSARSLELRLEGVRAETSELG 1404
Cdd:COG1196    749 EEEALEELPEPPDLEELERELERLEREIEALG 780
PTZ00121 PTZ00121
MAEBL; Provisional
 526-1283 6.76e-18

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 90.97  E-value: 6.76e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  526 IHSALHKRQLQVQDMRGRYEASQDLLGSVRKQLSDSEG--ERRGLEEQLQRLRDQTATSVQAQEDAQREAQRLRSANEIl 603
Cdd:PTZ00121  1055 NHEGKAEAKAHVGQDEGLKPSYKDFDFDAKEDNRADEAteEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEA- 1133

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  604 srekgnlshslqvaqQQAEDLRQELEKLQAAQEELRRQHTQLEDQQEDTVQEGARARRELERSHRQLEqleVKRSGltke 683
Cdd:PTZ00121  1134 ---------------RKAEDARKAEEARKAEDAKRVEIARKAEDARKAEEARKAEDAKKAEAARKAEE---VRKAE---- 1191

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  684 lvEVREAlscavlqRDVLQTEKAEVAEALTKAE-AGRAQLELSVTKLRAEEASLRDSlskmsalNESLAQDKLELNRLIA 762
Cdd:PTZ00121  1192 --ELRKA-------EDARKAEAARKAEEERKAEeARKAEDAKKAEAVKKAEEAKKDA-------EEAKKAEEERNNEEIR 1255

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  763 QLEEEKAALLGRQQQAEHAtslavEKQERLEQLRLEQEVERqglegslcvAEQAREAlgqqilvlrSERSHLQEqvAQLS 842
Cdd:PTZ00121  1256 KFEEARMAHFARRQAAIKA-----EEARKADELKKAEEKKK---------ADEAKKA---------EEKKKADE--AKKK 1310

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  843 RQLNGRDQELDQALRESQRQVEALERAAREK----EAMAKERAGLAVQLAAAEREGRTLSEETIRLRLEKEALESSLFDV 918
Cdd:PTZ00121  1311 AEEAKKADEAKKKAEEAKKKADAAKKKAEEAkkaaEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEK 1390

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  919 QR-QLAQLEARREQLEADSQALLLAKETLTGELAGLRQQVTATEE--KAALDKELMTQKLVQAERETQASLREQRAaheE 995
Cdd:PTZ00121  1391 KKaDEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEakKKAEEAKKADEAKKKAEEAKKAEEAKKKA---E 1467

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  996 DLQRLQREKEAAWRELQAERAQLQGQLQQEREELLARMEAEKEELSEEIAALQQERDEGLLLAEsEKQQALSLKESEKTA 1075
Cdd:PTZ00121  1468 EAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAE-EAKKADEAKKAEEKK 1546

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1076 LSEKLMGTRHSLAAisleMERQKRDAQSRQEQDRNTVNALTSELRDL---------------------RAQLEEATAAHA 1134
Cdd:PTZ00121  1547 KADELKKAEELKKA----EEKKKAEEAKKAEEDKNMALRKAEEAKKAeearieevmklyeeekkmkaeEAKKAEEAKIKA 1622

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1135 QQVK---ELQEQTGNLGRQREACMREAEELRTQLRLLEDTRDGLRRELLEAQRKVRDSQDSSEAHRQEASELRRSLSEGT 1211
Cdd:PTZ00121  1623 EELKkaeEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAK 1702

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1958776745 1212 KEREALRRSNEELRTA--VKKAESER-ISLKLANEDKEQKLALLEEARMSvAKEAGELRASLQEVERSRLEARRE 1283
Cdd:PTZ00121  1703 KAEELKKKEAEEKKKAeeLKKAEEENkIKAEEAKKEAEEDKKKAEEAKKD-EEEKKKIAHLKKEEEKKAEEIRKE 1776
PTZ00121 PTZ00121
MAEBL; Provisional
 954-1662 1.79e-12

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 73.25  E-value: 1.79e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  954 RQQVTATEEKAALD--KELMTQKLVQAERETQASLREQRAAHEEDLQRLQ--REKEAAWRELQAERAQLQGQLQQEREEL 1029
Cdd:PTZ00121  1088 RADEATEEAFGKAEeaKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEdaRKAEEARKAEDAKRVEIARKAEDARKAE 1167

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1030 LARMEAEKEELSEEIAALQQERDEGLLLAESEK--QQALSLKESEKTALSEKLMGTRHSLAAISLEMERQKRDAQSRQEQ 1107
Cdd:PTZ00121  1168 EARKAEDAKKAEAARKAEEVRKAEELRKAEDARkaEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEE 1247

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1108 DRNTVNALTSELRDLRAQLEEATAAHAQQVKELQEqtgnlgrqreacMREAEELRT--QLRLLEDTR--DGLRRELLEAq 1183
Cdd:PTZ00121  1248 ERNNEEIRKFEEARMAHFARRQAAIKAEEARKADE------------LKKAEEKKKadEAKKAEEKKkaDEAKKKAEEA- 1314

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1184 RKVRDSQDSSEAHRQEASELRRSLSEGTKEREALRRSNEELRTAVKKAESERISLKLANEDKEQKLALL----EEARMS- 1258
Cdd:PTZ00121  1315 KKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAkkkaEEKKKAd 1394

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1259 -VAKEAGELRASLQEVERSRlEARRELQELRRQMKTL-DSDNGRLGREladlQSRLALGERTEKESRREVLGLRQKVLKG 1336
Cdd:PTZ00121  1395 eAKKKAEEDKKKADELKKAA-AAKKKADEAKKKAEEKkKADEAKKKAE----EAKKADEAKKKAEEAKKAEEAKKKAEEA 1469

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1337 ESSLEALKQelqgSQRKLQEQEAEFRARERGllGSLEEARGAE--KKLLDSARSLELRL---EGVRAETSELGLRLSAAE 1411
Cdd:PTZ00121  1470 KKADEAKKK----AEEAKKADEAKKKAEEAK--KKADEAKKAAeaKKKADEAKKAEEAKkadEAKKAEEAKKADEAKKAE 1543

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1412 GRAQGLEV----ELARVEAQRRVAEAQlgglRSALRRGLGLGRVssspareapaggsgdglsspsplEYSPRSQPPSPGP 1487
Cdd:PTZ00121  1544 EKKKADELkkaeELKKAEEKKKAEEAK----KAEEDKNMALRKA-----------------------EEAKKAEEARIEE 1596

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1488 VASPAPPDLDPEAvrdalrdflQELRSAQRERDElrvqtstlSQQLAEMEAERDHAASRAKQLQKAVAESEEAwRSADRR 1567
Cdd:PTZ00121  1597 VMKLYEEEKKMKA---------EEAKKAEEAKIK--------AEELKKAEEEKKKVEQLKKKEAEEKKKAEEL-KKAEEE 1658

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1568 LSGAQAELALQEESVRRSRRECRATldqmavlERSLQATESELRASQEKVNKMKATEVKLESDKRRLKEVLDASESRSIK 1647
Cdd:PTZ00121  1659 NKIKAAEEAKKAEEDKKKAEEAKKA-------EEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIK 1731

                          730
                   ....*....|....*
gi 1958776745 1648 LELQRRALEGELQRS 1662
Cdd:PTZ00121  1732 AEEAKKEAEEDKKKA 1746
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 569-1295 7.25e-11

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 67.84  E-value: 7.25e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  569 EEQLQRLRDQTATSVQaqeDAQReaqRLRSANEILSREKGNLSHSLQVAQQQAEDLRQELEKLQAAQEELRRQHTQLEDQ 648
Cdd:pfam15921   73 KEHIERVLEEYSHQVK---DLQR---RLNESNELHEKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQ 146

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  649 QEDTVQ--EGARARRE--LERSHRQLEQLE---VKRSGLTKE----LVEVREALSCAVLQRDVLQTEK-AEVAEALTKAe 716
Cdd:pfam15921  147 LQNTVHelEAAKCLKEdmLEDSNTQIEQLRkmmLSHEGVLQEirsiLVDFEEASGKKIYEHDSMSTMHfRSLGSAISKI- 225

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  717 agRAQLELSVTKLRAEEASLRDSLSKMsalnESLAQDKLEL------NRLIAQLEEEKAALLGRQQQAEHATSLAVEKQE 790
Cdd:pfam15921  226 --LRELDTEISYLKGRIFPVEDQLEAL----KSESQNKIELllqqhqDRIEQLISEHEVEITGLTEKASSARSQANSIQS 299

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  791 RLEQLR----------------LEQEVE--RQGLEGSLCVAEQAREALGQQILVLRSERSHLQEQVAQLSRQLNGRDQEL 852
Cdd:pfam15921  300 QLEIIQeqarnqnsmymrqlsdLESTVSqlRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQL 379

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  853 DQALRESQRQVEALERAAREKEAMAKERAGLAVQLAAAEREGRTLSEETIRLRLEKEALESSL-FDVQRQLAQLEARREQ 931
Cdd:pfam15921  380 QKLLADLHKREKELSLEKEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECqGQMERQMAAIQGKNES 459

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  932 LEADSqALLLAKETLTGELAGLRQQVTA------TEEKAALDKELMTQKLVQAERETQASLREQRAAHEEDLQRLQ--RE 1003
Cdd:pfam15921  460 LEKVS-SLTAQLESTKEMLRKVVEELTAkkmtleSSERTVSDLTASLQEKERAIEATNAEITKLRSRVDLKLQELQhlKN 538

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1004 KEAAWRELQAERAQLQGQLqQEREELLARMEAEKEELSEEIAalQQERDEGLLLAESEK------QQALSLKESeKTALS 1077
Cdd:pfam15921  539 EGDHLRNVQTECEALKLQM-AEKDKVIEILRQQIENMTQLVG--QHGRTAGAMQVEKAQlekeinDRRLELQEF-KILKD 614

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1078 EKLMGTRHSLAAIS-LEMERQK------------RDAQSRQEQDRNTVNALTSELRDLRAQLEEATAAHAQQVKELQEQT 1144
Cdd:pfam15921  615 KKDAKIRELEARVSdLELEKVKlvnagserlravKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTT 694

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1145 GNLGRQREACMREAEELRTQLRLLEDTRDGLRRELLEAQRKVRDSQDSSEAHRQEASELRRSLSEGTKEREALRRSNEEL 1224
Cdd:pfam15921  695 NKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKL 774

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1958776745 1225 RTAVKKAESERISLKLANEDKEQKLALLEE--ARMSVAKEagelRASLQEVERSRLEARRELQELRRQMK-TLD 1295
Cdd:pfam15921  775 SQELSTVATEKNKMAGELEVLRSQERRLKEkvANMEVALD----KASLQFAECQDIIQRQEQESVRLKLQhTLD 844
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1048-1883 1.92e-09

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 63.07  E-value: 1.92e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1048 QQERDEGLLLAESEKQQALSLKESEKTAL-----SEKLMGTRHSLAAISLEMERQKRDAQSRQEQdRNTVNALTSELRDL 1122
Cdd:pfam02463  182 TENLAELIIDLEELKLQELKLKEQAKKALeyyqlKEKLELEEEYLLYLDYLKLNEERIDLLQELL-RDEQEEIESSKQEI 260

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1123 RAQLEEATAAHAQQVKELQEQtGNLGRQREACMREAEELRTQLRLLEDTRDGLRRELLEAQRKVRDSQDSSEAHRQEASE 1202
Cdd:pfam02463  261 EKEEEKLAQVLKENKEEEKEK-KLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEE 339

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1203 LRRSLSEGTKEREALRRSNEELRTAVKKAESERislklanEDKEQKLALLEEARMSVAKEAGELRASLQEVERSRLEARR 1282
Cdd:pfam02463  340 LEKELKELEIKREAEEEEEEELEKLQEKLEQLE-------EELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLE 412

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1283 ELQELRRQMKTLDSDNGRLGRELADLQSRLALGERTEKESRREVLGLRQKVLKGESSLEALKQELQGSQRKLQEQEAEFR 1362
Cdd:pfam02463  413 LARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSR 492

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1363 ARERGLLGSLEEARGAEKKLLDSARSLELRLEGVRAETSELGLRLSAAEGRAQGLEVELARVEAQRRVAEAQLGGLRSAL 1442
Cdd:pfam02463  493 QKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTE 572

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1443 RRGLGLGRVSSSPAREAPAGGSGDGLSSPSPLEYSPRSQPPSPGPVASPAPPDLDPEAVRDALRDFLQELRSAQRERDEL 1522
Cdd:pfam02463  573 LPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGV 652

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1523 RVQTSTLSQQLAEMEAERDHAASRAKQLQKAVAESEEAWRSADRRLSGAQAELALQEESVRRSRRECRATLDQMAVLERS 1602
Cdd:pfam02463  653 SLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQD 732

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1603 LQATESELrasqekvNKMKATEVKLESDKRRLKEVLDASESRSIKLELQRRALEGELQRSRLGLGDREAHAQALQDRVDS 1682
Cdd:pfam02463  733 KINEELKL-------LKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRA 805

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1683 LQRQVADSEVKAGTLQLTVERLSGALAKVEESEGTLRSKVQSLTDALAQSSASLTSSQDKNLYLQKALSTCEHDRQVLQE 1762
Cdd:pfam02463  806 LEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLK 885

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1763 RLDAARQALSEARRQSSSLGEQVQTLRGELANLELQRGDAEGQLQQLQQVLRQRQEGEAVAlrSVQKLQEERRLLQERLG 1842
Cdd:pfam02463  886 DELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEAD--EKEKEENNKEEEEERNK 963

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|.
gi 1958776745 1843 SLQRALAQLEAEKRELERSALQLDKDRVALRKTLDKVEREK 1883
Cdd:pfam02463  964 RLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEK 1004
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1721-1984 2.44e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 59.57  E-value: 2.44e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1721 KVQSLTDALAQSSASLTSSQDKNLYLQKALSTCEHDRQVLQ-ERLDA-----------ARQALSEARRQSSSLGEQVQTL 1788
Cdd:COG1196    214 RYRELKEELKELEAELLLLKLRELEAELEELEAELEELEAElEELEAelaeleaeleeLRLELEELELELEEAQAEEYEL 293

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1789 RGELANLELQRGDAEGQLQQLQQVLRQRQEGEAVALRSVQKLQEERRLLQERLGSLQRALAQLEAEKRELERSALQLDKD 1868
Cdd:COG1196    294 LAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAE 373

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1869 RVALRKTLDKVEREKLRSHEDTLRLNAERGRLDRTLTGAELDLAEAQQQIQHLEAQVVEVLER--NHSPVQVEADEQHLE 1946
Cdd:COG1196    374 LAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEeeEEEEALEEAAEEEAE 453

                          250       260       270
                   ....*....|....*....|....*....|....*...
gi 1958776745 1947 LQQEVERLRSAQVRTERTLEARERAHRQRVSGLEEQVQ 1984
Cdd:COG1196    454 LEEEEEALLELLAELLEEAALLEAALAELLEELAEAAA 491
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
830-1364 7.47e-08

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 57.74  E-value: 7.47e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  830 ERSHLQEQVAQLSRQLNGRDQELDQALRESQRQVEALERAAREKEAMAKERAGLAVqLAAAEREGRTLSEETIRlrlEKE 909
Cdd:PRK02224   200 EEKDLHERLNGLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERREELET-LEAEIEDLRETIAETER---ERE 275

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  910 ALESSLFDVQRQLAQLEARREQL-------EADSQALLLAKETLTGELAGLRQqvtateekaaldkELMTQKLVQAERET 982
Cdd:PRK02224   276 ELAEEVRDLRERLEELEEERDDLlaeagldDADAEAVEARREELEDRDEELRD-------------RLEECRVAAQAHNE 342

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  983 QA-SLREQRAAHEEDLQRLQREKEAAWRELQAERAQLQgqlqqEREELLARMEAEKEELSEEIAALQQERDEglllAESE 1061
Cdd:PRK02224   343 EAeSLREDADDLEERAEELREEAAELESELEEAREAVE-----DRREEIEELEEEIEELRERFGDAPVDLGN----AEDF 413

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1062 kqqaLSLKESEKTALSEKLMGTRHSL--AAISLEMERQKRDA---------------QSRQEQDRNTVNALTSELRDLRA 1124
Cdd:PRK02224   414 ----LEELREERDELREREAELEATLrtARERVEEAEALLEAgkcpecgqpvegsphVETIEEDRERVEELEAELEDLEE 489

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1125 QLEEATAAH---------AQQVKELQEQTGNLGRQREACMREAEELRTQLRLLEDTRDGLRRELLEAQRKVRDSQDSSEA 1195
Cdd:PRK02224   490 EVEEVEERLeraedlveaEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEE 569

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1196 HRQEASELRRSLSEGTKEREALRRSnEELRTAVKKAESERISLKlaneDKEQKLALLEEARMSVAKEAGELRASLQ-EVE 1274
Cdd:PRK02224   570 AREEVAELNSKLAELKERIESLERI-RTLLAAIADAEDEIERLR----EKREALAELNDERRERLAEKRERKRELEaEFD 644

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1275 RSRLE-ARRELQELRRQMKTLDSDNGRLGRELADLQSRLAlGERTEKESRREVLGLRQKVLKGESSLEALKQELQGSQRK 1353
Cdd:PRK02224   645 EARIEeAREDKERAEEYLEQVEEKLDELREERDDLQAEIG-AVENELEELEELRERREALENRVEALEALYDEAEELESM 723

                          570
                   ....*....|.
gi 1958776745 1354 LQEQEAEFRAR 1364
Cdd:PRK02224   724 YGDLRAELRQR 734
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 73-480 4.43e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 51.86  E-value: 4.43e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745   73 PEMASLLSLQEENQLLQQELSRVEDLLAQSRAERDELAIKYNAINERLEQAVRLETGELEAQEprglvrQSVELRRQLQE 152
Cdd:COG1196    306 RLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALL------EAEAELAEAEE 379

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  153 EQASYRRKLQAYQEGQQRQAQLVQRLQAKILQYKKQCSEMEKQLLERSTELEQQRLRDTEHSQDLDRALLRLEEEQQRSA 232
Cdd:COG1196    380 ELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEE 459

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  233 SLAQVNDMLREQLDQANLANQTLSEDICKVTSdwtrscKELEQREATWRREEESFNAYFSSEHSRLLLLWRQVMGLRRMA 312
Cdd:COG1196    460 ALLELLAELLEEAALLEAALAELLEELAEAAA------RLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVE 533

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  313 SEVKMGTERDLLQLGGELVRTSRavqEVGLGLSASLQRAESRAEAALEKQKLLQAQLEEQLRAKLLREKDLAQLQVQSDL 392
Cdd:COG1196    534 AAYEAALEAALAAALQNIVVEDD---EVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLRE 610

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  393 DKADLSARVTELALSVEHLQNQNTEKDQVNRTLSDKLEALESLRLQEQTTLDTEDGEGLQQTLRDLAQAALSDTESGVQL 472
Cdd:COG1196    611 ADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAE 690


                   ....*...
gi 1958776745  473 SNSERTAD 480
Cdd:COG1196    691 EELELEEA 698
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 55-660 6.38e-05

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 48.19  E-value: 6.38e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745   55 EIITSNLSQPETPAPLQVPEMASLLSLQEE-----NQLLQQELSRVEDLLAQSRAERDELAIKYNAINERLEQAVRLETG 129
Cdd:pfam15921  277 EVEITGLTEKASSARSQANSIQSQLEIIQEqarnqNSMYMRQLSDLESTVSQLRSELREAKRMYEDKIEELEKQLVLANS 356

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  130 EL-EAQEPRGLVRQ-SVELRRQLQEEQASYRRKLQAYQEGQQRQAQLVQR----------LQAKILQYKKQCSEMEKQLL 197
Cdd:pfam15921  357 ELtEARTERDQFSQeSGNLDDQLQKLLADLHKREKELSLEKEQNKRLWDRdtgnsitidhLRRELDDRNMEVQRLEALLK 436

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  198 ERSTELEQQRLRDTEHSQDLDRALlrlEEEQQRSASLAQVNDMLREQLDQANLANQTLsEDICKVTSDWTRSCKELEqre 277
Cdd:pfam15921  437 AMKSECQGQMERQMAAIQGKNESL---EKVSSLTAQLESTKEMLRKVVEELTAKKMTL-ESSERTVSDLTASLQEKE--- 509

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  278 atwrREEESFNAYFSSEHSRLLLLWRQVMGLRRMASEVK-MGTERDLLQLggELVRTSRAVQEVGLGLSASLQRA--ESR 354
Cdd:pfam15921  510 ----RAIEATNAEITKLRSRVDLKLQELQHLKNEGDHLRnVQTECEALKL--QMAEKDKVIEILRQQIENMTQLVgqHGR 583

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  355 AEAALEKQKllqAQLEEQLRAKLLREKDLAQLQVQSDLDKADLSARVTELALSVEHLQNQNTEKDQVNRTLSDKLEALES 434
Cdd:pfam15921  584 TAGAMQVEK---AQLEKEINDRRLELQEFKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQLLN 660

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  435 LRLQEQTTLD--TEDGEGLQQTLRDLAQAALSDTES-GVQLSNSERTADTSDGSFRGLFGqrtptpprhsSPGRGRSPRR 511
Cdd:pfam15921  661 EVKTSRNELNslSEDYEVLKRNFRNKSEEMETTTNKlKMQLKSAQSELEQTRNTLKSMEG----------SDGHAMKVAM 730

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  512 GLspacsdsstltlihsalhkrQLQVQDMRGRYEASQDLLGSVRKQLSDSEGERRGLEEQLQRLRDQTATsvqaqedaqr 591
Cdd:pfam15921  731 GM--------------------QKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELST---------- 780

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1958776745  592 eaqrlrsaneiLSREKGNLSHSLQVAQQQAEDLRQELEKLQAAQEELRRQHTQLEDQQEDTVQEGARAR 660
Cdd:pfam15921  781 -----------VATEKNKMAGELEVLRSQERRLKEKVANMEVALDKASLQFAECQDIIQRQEQESVRLK 838
PspC_subgroup_1 NF033838
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, ...
 1274-1624 9.44e-03

pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.


Pssm-ID: 468201 [Multi-domain]  Cd Length: 684  Bit Score: 41.15  E-value: 9.44e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1274 ERSRLEARRELQ-ELRRQMKTLDSDNGRLGRELADLQSRLALGERTEK----ESRREVLGLRQKVLK---GESSLEALKQ 1345
Cdd:NF033838   109 EKSEAELTSKTKkELDAAFEQFKKDTLEPGKKVAEATKKVEEAEKKAKdqkeEDRRNYPTNTYKTLEleiAESDVEVKKA 188

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1346 ELQGSQRKLQEQEAEfrarergllgslEEARGAEKKLlDSARSLELRLEGVRAETSElglrlsaAEGRAQGLEVELARVE 1425
Cdd:NF033838   189 ELELVKEEAKEPRDE------------EKIKQAKAKV-ESKKAEATRLEKIKTDREK-------AEEEAKRRADAKLKEA 248

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1426 AQRRVAEAQLGGLRSALRRGlglgrVSSSPAReapaggsgdglssPSPLEYSPRSQPPSPGPVASPApPDLDPEA-VRDA 1504
Cdd:NF033838   249 VEKNVATSEQDKPKRRAKRG-----VLGEPAT-------------PDKKENDAKSSDSSVGEETLPS-PSLKPEKkVAEA 309

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1505 LRDFLQELRSAQRERDELRvqtstlsqqlaemeaeRDHAASRAKQLQKAVAESEEAWRSADRRLSGAQAELALQEESVRR 1584
Cdd:NF033838   310 EKKVEEAKKKAKDQKEEDR----------------RNYPTNTYKTLELEIAESDVKVKEAELELVKEEAKEPRNEEKIKQ 373

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*
gi 1958776745 1585 SRRECRATLDQMAVLE-----RSLQATESELRASQEKVNKMKATE 1624
Cdd:NF033838   374 AKAKVESKKAEATRLEkiktdRKKAEEEAKRKAAEEDKVKEKPAE 418
 
Name Accession Description Interval E-value
Rootletin pfam15035
Ciliary rootlet component, centrosome cohesion;
158-334 1.10e-49

Ciliary rootlet component, centrosome cohesion;


Pssm-ID: 464459 [Multi-domain]  Cd Length: 190  Bit Score: 175.23  E-value: 1.10e-49
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  158 RRKLQAYQEGQQRQAQLVQRLQAKILQYKKQCSEMEKQLLERSTELEQQRL-------------RDTEHSQDLDRALLRL 224
Cdd:pfam15035    1 RRKLQAYQEAQQRQAQLVQKLQAKVLQYKKRCSELEQQLLEKTSELEKTELllrkltleprlqrLEREHSADLEEALIRL 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  225 EEEQQRSASLAQVNDMLREQLDQANLANQTLSEDICKVTSDWTRSCKELEQREATWRREEESFNAYFSSEHSRLLLLWRQ 304
Cdd:pfam15035   81 EEERQRSESLSQVNSLLREQLEQASRANEALREDLQKLTNDWERAREELEQKESEWRKEEEAFNEYLSSEHSRLLSLWRE 160

                          170       180       190
                   ....*....|....*....|....*....|
gi 1958776745  305 VMGLRRMASEVKMGTERDLLQLGGELVRTS 334
Cdd:pfam15035  161 VVAVRRQFTELKTATERDLSELKTEFSRTS 190
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 532-1072 1.16e-26

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 119.27  E-value: 1.16e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  532 KRQLQVQDMRGRYEASQDLLGSVRKQLSDSEGERRGLEEQLQRLRDQTATSVQAQEDAQREAQRLRSANEILSREKGNLS 611
Cdd:COG1196    222 LKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLE 301

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  612 HSLQVAQQQAEDLRQELEKLQAAQEELRRQHTQLEDQQEDTVQEGARARRELERSHRQLEQLEVKRSGLTKELVEVREAL 691
Cdd:COG1196    302 QDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEEL 381

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  692 SCAVLQRDVLQTEKAEVAEALTKAEAGRAQLELSVTKLRAEEASLRDSLSKMSALNESLAQDKLELNRLIAQLEEEKAAL 771
Cdd:COG1196    382 EELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEAL 461

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  772 LGRQQQAEHATSLAVEKQERLEQLRLEQEVERQGLEGSLCVAEQAREALGQQILVLRSERSHLQEQVAQLSRQLNGRDQE 851
Cdd:COG1196    462 LELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALE 541

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  852 LDQALRESQRQVEALERAAREKEAMAKERAGLAVQLAAAEREGRTLSEETIRLRLEKEALESSLFDVQRQLAQLEARREQ 931
Cdd:COG1196    542 AALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDT 621

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  932 LEADS--QALLLAKETLTGELAGLRQQVTATEEKAALDKELMTQKLVQAERETQASLREQRAAHEEDLQRLQREKEAAWR 1009
Cdd:COG1196    622 LLGRTlvAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLA 701

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1958776745 1010 ELQAERAQLQGQLQQEREELLARMEAEKEELSEEIAALQQERDEGLLLAESEKQQALSLKESE 1072
Cdd:COG1196    702 EEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEE 764
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 622-1217 1.48e-26

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 118.89  E-value: 1.48e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  622 EDLRQELEKLQAAQEELRRQHTQLEDQQEDtvqegARARREL--ERSHRQLEQLEVKRSGLTKELVEVREALSCAVLQRD 699
Cdd:COG1196    182 EATEENLERLEDILGELERQLEPLERQAEK-----AERYRELkeELKELEAELLLLKLRELEAELEELEAELEELEAELE 256

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  700 VLQTEKAEVAEALTKAEAGRAQLELSVTKLRAEEASLRDSLSKMSALNESLAQDKLELNRLIAQLEEEKAALLGRQQQAE 779
Cdd:COG1196    257 ELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELE 336

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  780 HATSLAVEKQERLEQLRLEQEVERQGLEGSLCVAEQAREALGQQILVLRSERSHLQEQVAQLSRQLNGRDQELDQALRES 859
Cdd:COG1196    337 EELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERL 416

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  860 QRQVEALERAAREKEAMAKERAGLAVQLAAAEREGRTLSEETIRLRLEKEALESSLFDVQRQLAQLEARREQLEADSQAL 939
Cdd:COG1196    417 ERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLL 496

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  940 LLAKETLTGELAGLRQQVTATEEK---AALDKELMTQKLVQAERETQASLREQRAAHEEDLQRLQREKEAAWRELQAERA 1016
Cdd:COG1196    497 LEAEADYEGFLEGVKAALLLAGLRglaGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATF 576

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1017 QLQGQLQQEREELLARMEAEKEELSEEIAALQQERDEGLLLAESEKQQALSLKESEKTA--LSEKLMGTRHSLAAISLEM 1094
Cdd:COG1196    577 LPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAAlrRAVTLAGRLREVTLEGEGG 656

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1095 ERQKRDAQSRQEQDRNTVNALTSELRDLRAQLEEATAAHAQQVKELQEQTGNLGRQREACMREAEELRTQLRLLEDTRDG 1174
Cdd:COG1196    657 SAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREE 736

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|...
gi 1958776745 1175 LRRELLEAQRKVRDSQDSSEAHRQEASELRRSLSEGTKEREAL 1217
Cdd:COG1196    737 LLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEAL 779
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1118-1851 5.05e-26

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 117.46  E-value: 5.05e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1118 ELRDLRAQLEEATAA-HAQQVKELQEQTGNLGRQREACMREAEELRTQLRLLEDTRDGLRRELLEAQRKVRDSQDSSEAH 1196
Cdd:TIGR02168  214 RYKELKAELRELELAlLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYAL 293

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1197 RQEASELRRSLSEGTKEREALRRSNEELRTAVKKAESERISLKLANEDKEQKLALLEEARMSVAKEAGELRASLQEVERS 1276
Cdd:TIGR02168  294 ANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESR 373

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1277 RLEARRELQELRR-------QMKTLDSDNGRLGRELADLQSRLA-LGERTEKESRREVLGLRQKVLKGESSLEALKQELQ 1348
Cdd:TIGR02168  374 LEELEEQLETLRSkvaqlelQIASLNNEIERLEARLERLEDRRErLQQEIEELLKKLEEAELKELQAELEELEEELEELQ 453

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1349 GSQRKLQEQEAEFRARERGLLGSLEEARGAEKKLLDSARSLELRLEGVRAETSELGLRLSAAEGRAQGLEV--ELARVEA 1426
Cdd:TIGR02168  454 EELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVlsELISVDE 533

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1427 QRRVA-EAQLGG-LRSALRRGLGLGRVSSSPAREAPAGGSG----DGLSSPSPLEYSPRSQPPSPGPVASPAPPDLDPEA 1500
Cdd:TIGR02168  534 GYEAAiEAALGGrLQAVVVENLNAAKKAIAFLKQNELGRVTflplDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPK 613

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1501 VRDALRDFL------QELRSA-----------------------------------------QRERDELRVQTSTLSQQL 1533
Cdd:TIGR02168  614 LRKALSYLLggvlvvDDLDNAlelakklrpgyrivtldgdlvrpggvitggsaktnssilerRREIEELEEKIEELEEKI 693

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1534 AEMEAERDHAASRAKQLQKAVAESEEAWRSADRRLSGAQAELAlqeesvrRSRRECRATLDQMAVLERSLQATESELRAS 1613
Cdd:TIGR02168  694 AELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLA-------RLEAEVEQLEERIAQLSKELTELEAEIEEL 766

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1614 QEKVNKMKATEVKLESDKRRLKEVLDASESRSIKLELQRRALEGELQRSRLGLGDREAHAQALQDRVDSLQRQVADSEVK 1693
Cdd:TIGR02168  767 EERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQ 846

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1694 AGTLQLTVERLSGALAKVEESEGTLRSKVQSLTDALAQSSASLTSsqdknlyLQKALSTCEHDRQVLQERLDAARQALSE 1773
Cdd:TIGR02168  847 IEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALAL-------LRSELEELSEELRELESKRSELRRELEE 919

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1958776745 1774 ARRQSSSLGEQVQTLRGELANLeLQRGDAEGQLQqlqqvlrqrqegEAVALRSVQKLQEERRLLQERLGSLQRALAQL 1851
Cdd:TIGR02168  920 LREKLAQLELRLEGLEVRIDNL-QERLSEEYSLT------------LEEAEALENKIEDDEEEARRRLKRLENKIKEL 984
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 535-1356 7.39e-26

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 117.08  E-value: 7.39e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  535 LQVQDMRGRYEASQDLLGSVRKQLSDSEGERRGLEEQLQRLRDQTATSVQAQEDAQREAQRLRSANEILSREKGNLSHSL 614
Cdd:TIGR02168  232 LRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERL 311

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  615 QVAQQQAEDLRQELEKLQAAQEELRRQHTQLEDQQEDTVQEGARARRELERSHRQLEQLEVKRSGLTKELVEVREALSCA 694
Cdd:TIGR02168  312 ANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQL 391

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  695 VLQRDVLQTEkaevaeaLTKAEAGRAQLELSVTKLRAEEASLRDSLS--KMSALNESLAQDKLELNRLIAQLEEEKAALL 772
Cdd:TIGR02168  392 ELQIASLNNE-------IERLEARLERLEDRRERLQQEIEELLKKLEeaELKELQAELEELEEELEELQEELERLEEALE 464

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  773 GRQQQAEHATSLAVEKQERLEQLRLEQEVERQGLEGSLCVAEQAREALGQQilvlrSERSHLQEQVAQLSRQLNGRDQEL 852
Cdd:TIGR02168  465 ELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQ-----SGLSGILGVLSELISVDEGYEAAI 539

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  853 DQALRESQRQ--VEALERAAREKEAMAKERAGLAVQLAAAEREGRTLSEETIRLRLEKEalesslfDVQRQLAQLEARRE 930
Cdd:TIGR02168  540 EAALGGRLQAvvVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIE-------GFLGVAKDLVKFDP 612

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  931 QLEADSQALL---LAKETLTGELAgLRQQVTATEEKAALDKELMTQKLVQAeretqaslreqRAAHEEDLQRLQREKEAA 1007
Cdd:TIGR02168  613 KLRKALSYLLggvLVVDDLDNALE-LAKKLRPGYRIVTLDGDLVRPGGVIT-----------GGSAKTNSSILERRREIE 680

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1008 wrELQAERAQLQGQLQQEREELlarmeaekeelseeiAALQQERDeglllaesEKQQALSLKESEKTALSEKLMGTRHSL 1087
Cdd:TIGR02168  681 --ELEEKIEELEEKIAELEKAL---------------AELRKELE--------ELEEELEQLRKELEELSRQISALRKDL 735

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1088 AAISLEmERQKRDAQSRQEQDRNTVNALTSELRDLRAQLEEATAAHAQQVKELQEQTGNLGRQREACMREAEELRTQLRL 1167
Cdd:TIGR02168  736 ARLEAE-VEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTL 814

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1168 LEDTRDGLRRELLEAQRKVRDSQDSSEAHRQEASELRRSLSEGTKEREALRRSNEELRTAVKKAESERislklanedkeq 1247
Cdd:TIGR02168  815 LNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNER------------ 882

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1248 klALLEEARMSVAKEAGELRASLQEVERSRLEARRELQELRRQMKTLDSDNGRLGRELADLQSRLALGERTEKEsrrevl 1327
Cdd:TIGR02168  883 --ASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLE------ 954

                          810       820
                   ....*....|....*....|....*....
gi 1958776745 1328 GLRQKVLKGESSLEALKQELQGSQRKLQE 1356
Cdd:TIGR02168  955 EAEALENKIEDDEEEARRRLKRLENKIKE 983
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 529-1053 1.18e-24

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 112.72  E-value: 1.18e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  529 ALHKRQLQVQDMRGRYEASQDLLGSVRKQLSDSEGERRGLEEQLQRLRDQTATSVQAQEDAQREAQRLRSANEILSREKG 608
Cdd:COG1196    261 ELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELE 340

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  609 NLSHSLQVAQQQAEDLRQELEKLQAAQEELRRQHTQLEDQQEDTVQEGARARRELERSHRQLEQLEVKRSGLTKELVEVR 688
Cdd:COG1196    341 ELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLE 420

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  689 EALSCAVLQRDVLQTEKAEVAEALTKAEAGRAQLELSVTKLRAEEASLRDSLskmsalnESLAQDKLELNRLIAQLEEEK 768
Cdd:COG1196    421 EELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEA-------ALLEAALAELLEELAEAAARL 493

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  769 AALLGRQQQAEHATSLAVEKQERLEQLRLEQEVERQGLEGSLCVAEQAREALGQQILVLRSERSHLQEQVAQLSRQLNGR 848
Cdd:COG1196    494 LLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGR 573

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  849 DQELDQALRESQRQVEALERAAREKEAMAKERAGLAVQLAAAEREGRTLSEETIRLRLEKEALESSLFDVQRQLAQLEAR 928
Cdd:COG1196    574 ATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEG 653

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  929 REQLEADSQALLLAKETLTGELAGLRQQVTATEEKAALDKELMTQKLVQAERETQASLREQRAAHEEDLQRLQREKEAAW 1008
Cdd:COG1196    654 EGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAE 733

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....*
gi 1958776745 1009 RELQAERAQLQGQLQQEREELLARMEAEKEELSEEIAALQQERDE 1053
Cdd:COG1196    734 REELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEA 778
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 755-1427 8.85e-23

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 106.68  E-value: 8.85e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  755 LELNRLIAQLEEEKAALLGRQQQAEHATSLAVEKQERLEQLRLEQEVerqgLEGSLCVAEQAREALGQQILVLRSERSHL 834
Cdd:TIGR02168  232 LRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSE----LEEEIEELQKELYALANEISRLEQQKQIL 307

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  835 QEQVAQLSRQLNGRDQELDQALRESQRQVEALERAAREKEAMAKERAGLAVQLAAAEREGRTLSEETIRLRLEKEALESS 914
Cdd:TIGR02168  308 RERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSK 387

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  915 LFDVQRQLAQLEARREQLEADsqalllaKETLTGELAGLRQQVTATEEKAALDKELMTQKLVQAERETQASLREQRAAHE 994
Cdd:TIGR02168  388 VAQLELQIASLNNEIERLEAR-------LERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLE 460

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  995 EDLQRLQREKEAAWRELQAERAQLQgQLQQeREELLARMEAEKEELSEEIAALQQERdEGLLLAESEKQQALSLKESEKT 1074
Cdd:TIGR02168  461 EALEELREELEEAEQALDAAERELA-QLQA-RLDSLERLQENLEGFSEGVKALLKNQ-SGLSGILGVLSELISVDEGYEA 537

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1075 ALSEKLMGTRHSLAAISLEMERQKRDAQSRQEQDRNTVNALTS-------------------------ELRDLRAQLEEA 1129
Cdd:TIGR02168  538 AIEAALGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSikgteiqgndreilkniegflgvakDLVKFDPKLRKA 617

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1130 --------------TAAHAQQVKELQEQT------------------------GNLGRQRE--ACMREAEELRTQLRLLE 1169
Cdd:TIGR02168  618 lsyllggvlvvddlDNALELAKKLRPGYRivtldgdlvrpggvitggsaktnsSILERRREieELEEKIEELEEKIAELE 697

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1170 DTRDGLRRELLEAQRKVRDSQDSSEAHRQEASELRRSLSEGTKEREALRRSNEELRTAVKKAESERISLKLANEDKEQKL 1249
Cdd:TIGR02168  698 KALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEEL 777

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1250 ALLEEARMSVAKEAGELRASLQEVERSRLEARRELQELRRqmktldsDNGRLGRELADLQSRLALGERTEKESRREVLGL 1329
Cdd:TIGR02168  778 AEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNE-------EAANLRERLESLERRIAATERRLEDLEEQIEEL 850

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1330 RQKVLKGESSLEALKQELQGSQRKLQEQEAEFRARERGllgsLEEARGAEKKLLDSARSLELRLEGVRAETSELGLRLSA 1409
Cdd:TIGR02168  851 SEDIESLAAEIEELEELIEELESELEALLNERASLEEA----LALLRSELEELSEELRELESKRSELRRELEELREKLAQ 926

                          730
                   ....*....|....*...
gi 1958776745 1410 AEGRAQGLEVELARVEAQ 1427
Cdd:TIGR02168  927 LELRLEGLEVRIDNLQER 944
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1095-1656 1.48e-22

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 105.79  E-value: 1.48e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1095 ERQKRDAQSRQEqdrntvnaLTSELRDLRAQLEEATAAHAQ-QVKELQEQTGNLGRQREACMREAEELRTQLRLLEDTRD 1173
Cdd:COG1196    206 ERQAEKAERYRE--------LKEELKELEAELLLLKLRELEaELEELEAELEELEAELEELEAELAELEAELEELRLELE 277

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1174 GLRRELLEAQRKVRDSQDSSEAHRQEASELRRSLSEGTKEREALRRSNEELRTAVKKAESERISLKLANEDKEQKLALLE 1253
Cdd:COG1196    278 ELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAE 357

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1254 EARMSVAKEAGELRASLQEVERSRLEARRELQELRRQMKTLDSDNGRLGRELADLQSR----------LALGERTEKESR 1323
Cdd:COG1196    358 AELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERlerleeeleeLEEALAELEEEE 437

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1324 REVLGLRQKVLKGESSLEALKQELQGSQRKLQEQEAEFRARERGLLGSLEEARGAEKKLLDSARSLELRLEGVRAETSEL 1403
Cdd:COG1196    438 EEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLA 517

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1404 GLRLSAAEGR---------AQGLEVELARVEAQRRVAEAQLGGLRSALRRGLGLGRVSSSPAREAPAGGSGDGLSSPSPL 1474
Cdd:COG1196    518 GLRGLAGAVAvligveaayEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAI 597

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1475 EYSPRSQPPSPGPVASPAPPDLDPEAVRDAL-RDFLQELRSAQRERDELRVQTSTLSQQLAEMEAERDHAASRAKQLQKA 1553
Cdd:COG1196    598 GAAVDLVASDLREADARYYVLGDTLLGRTLVaARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEA 677

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1554 VAESEEAWRSADRRLSGAQAELALQEESVRRSRRECRATLDQMAVLERSLQATESELRASQEKVNKMKATEVKLESDKRR 1633
Cdd:COG1196    678 EAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELP 757

                          570       580
                   ....*....|....*....|...
gi 1958776745 1634 LKEVLDASESRSIKLELQRRALE 1656
Cdd:COG1196    758 EPPDLEELERELERLEREIEALG 780
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 568-1153 1.73e-22

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 105.79  E-value: 1.73e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  568 LEEQLQRLRDQTATSVQAQE--------DAQREAQRLRSANEILSREKGNLSHS---LQVAQQQAEDLRQELEKLQAAQE 636
Cdd:COG1196    198 LERQLEPLERQAEKAERYRElkeelkelEAELLLLKLRELEAELEELEAELEELeaeLEELEAELAELEAELEELRLELE 277

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  637 ELRRQHTQLEDQQEDTVQEGARARRELERSHRQLEQLEVKRSGLTKELVEVREALSCAVLQRDVLQTEKAEVAEALTKAE 716
Cdd:COG1196    278 ELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAE 357

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  717 AGRAQLELSVTKLRAEEASLRDSLSKMSALNESLAQDKLELNRLIAQLEEEKAALLGRQQQAEHATSLAVEKQERLEQLR 796
Cdd:COG1196    358 AELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEE 437

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  797 LEqeverqglegslcvAEQAREALGQQILVLRSERSHLQEQVAQLSRQLNGRDQELDQALRESQRqveALERAAREKEAM 876
Cdd:COG1196    438 EE--------------EEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAE---AAARLLLLLEAE 500

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  877 AKERAGLAVQLAAAEREGRTLSEETIRLRLEKEALESSLFDVQRQLAQLEARREQLEADSQALLLAKETLTGELAGLRQQ 956
Cdd:COG1196    501 ADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLD 580

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  957 VTATEEKAALDKELMTQK---LVQAERETQASLREQRAAHEEDLQRLQREKEAAWRELQAERAQLQGQLQQEREELLARM 1033
Cdd:COG1196    581 KIRARAALAAALARGAIGaavDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGG 660

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1034 EAEKEELSEEIAALQQERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLAAisLEMERQKRDAQSRQEQDRNTVN 1113
Cdd:COG1196    661 SLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEER--LEEELEEEALEEQLEAEREELL 738

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|
gi 1958776745 1114 ALTSELRDLRAQLEEATAAHAQQVKELQEQTGNLGRQREA 1153
Cdd:COG1196    739 EELLEEEELLEEEALEELPEPPDLEELERELERLEREIEA 778
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 813-1404 8.39e-22

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 103.48  E-value: 8.39e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  813 AEQAREALGQQILVLRSERSHLQEQVAQLSRQLNGRDQELDQALRESQRQVEALERAAREKEAMAKERAGLAVQLAAAER 892
Cdd:COG1196    209 AEKAERYRELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQA 288

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  893 EGRTLSEETIRLRLEKEALESSLFDVQRQLAQLEARREQLEADSQALLLAKETLTGELAGLRQQVTATEEKAALDKElmt 972
Cdd:COG1196    289 EEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEE--- 365

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  973 qKLVQAERETQASLREQRAAHEEDLQRLQREKEAAWRELQAERAqlqgqlQQEREELLARMEAEKEELSEEIAALQQERD 1052
Cdd:COG1196    366 -ALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEA------EEALLERLERLEEELEELEEALAELEEEEE 438

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1053 EGLLLAESEKQQALSLKESEKTALSEklmgtRHSLAAISLEMERQKRDAQSRQEQDRNTVNALTSELRDLRAQLEEATAA 1132
Cdd:COG1196    439 EEEEALEEAAEEEAELEEEEEALLEL-----LAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAA 513

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1133 HAQQVKELQEQTGNLGRQREACMREAEELRTQLRLLEDtrdglRRELLEAQRKVRDSQDSSEAHRQEASELRRSLSEGTK 1212
Cdd:COG1196    514 LLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNI-----VVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAAL 588

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1213 EREALRRSNEELRTAVKKAESERISLKLANEDKEQKLALLEEARMSVAKEAGELRASLQEVERSRLEARRELQELRRQMK 1292
Cdd:COG1196    589 AAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRR 668

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1293 TLDSDNGRLGRELADLQSRLALGERTEKESRREVLGLRQKVLKGESSLEALKQELQGSQRKLQEQEAEFRARERGLLGSL 1372
Cdd:COG1196    669 ELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELL 748

                          570       580       590
                   ....*....|....*....|....*....|..
gi 1958776745 1373 EEARGAEKKLLDSARSLELRLEGVRAETSELG 1404
Cdd:COG1196    749 EEEALEELPEPPDLEELERELERLEREIEALG 780
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 994-1709 4.85e-21

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 101.29  E-value: 4.85e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  994 EEDLQRLQREKEAA--WRELQAERAQLQGQLQQEReelLARMEAEKEELSEEIAALQQERDEgLLLAESEKQQALSLKES 1071
Cdd:TIGR02168  199 ERQLKSLERQAEKAerYKELKAELRELELALLVLR---LEELREELEELQEELKEAEEELEE-LTAELQELEEKLEELRL 274

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1072 EKTALSEK---LMGTRHSLAAISLEMERQKRDAQSRQEQDRNTVNALTSELRDLRAQLEEATAAHAQQVKELQEQTGNLG 1148
Cdd:TIGR02168  275 EVSELEEEieeLQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELE 354

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1149 RQREacmrEAEELRTQLRLLEDTRDGLRRELLEAQRKVRDSQDSSEAHRQEASELRRSLSEGTKEREALRRSNEELRTAV 1228
Cdd:TIGR02168  355 SLEA----ELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKL 430

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1229 KKAESERISLKLANEDKEqkLALLEEARMSVAKEAGELRASLQEVERSRLEARRELQELRRQMKTLD------SDNGRLG 1302
Cdd:TIGR02168  431 EEAELKELQAELEELEEE--LEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLErlqenlEGFSEGV 508

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1303 RELADLQSRLA-----LGERTEKESRRE-----VLGLR-QKVL-----KGESSLEALKQELQG----------SQRKLQE 1356
Cdd:TIGR02168  509 KALLKNQSGLSgilgvLSELISVDEGYEaaieaALGGRlQAVVvenlnAAKKAIAFLKQNELGrvtflpldsiKGTEIQG 588

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1357 QEAEFRARERGLLGSLEEARGAEKKL--------------------LDSARSLELRLEGVRAETSELGLRLSAAEGRAQG 1416
Cdd:TIGR02168  589 NDREILKNIEGFLGVAKDLVKFDPKLrkalsyllggvlvvddldnaLELAKKLRPGYRIVTLDGDLVRPGGVITGGSAKT 668

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1417 -------------LEVELARVEAQRRVAEAQLGGLRSALRRGLGLGRVSSSPAREAPAGGSGDglsspspleysprsqpp 1483
Cdd:TIGR02168  669 nssilerrreieeLEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISAL----------------- 731

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1484 spgpvaspappDLDPEAVRDALRDFLQELRSAQRERDELRVQTSTLSQQLAEMEAERDHAASRAKQLQKAVAESEEAWRS 1563
Cdd:TIGR02168  732 -----------RKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKA 800

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1564 ADRRLSGAQAELALQEESVRRSRRECRATLDQMAVLERSLQATESELRASQEKVNKMKATEVKLESDKRRLKEVLDASES 1643
Cdd:TIGR02168  801 LREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLN 880

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958776745 1644 RSIKLELQRRALEGELQRSRLGLGDREAHAQALQDRVDSLQRQVADSEVKAGTLQLTVERLSGALA 1709
Cdd:TIGR02168  881 ERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLS 946
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 856-1444 1.27e-20

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 99.63  E-value: 1.27e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  856 LRESQRQVEALER---AAREKEAMAKERAGLAVQLAAAERegRTLSEETIRLRLEKEALESSLFDVQRQLAQLEARREQL 932
Cdd:COG1196    195 LGELERQLEPLERqaeKAERYRELKEELKELEAELLLLKL--RELEAELEELEAELEELEAELEELEAELAELEAELEEL 272

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  933 EADSQALLLAKETLTGELAGLRQQVTATEEKaaldkelmtqklVQAERETQASLREQRAAHEEDLQRLQREKEAAWRELQ 1012
Cdd:COG1196    273 RLELEELELELEEAQAEEYELLAELARLEQD------------IARLEERRRELEERLEELEEELAELEEELEELEEELE 340

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1013 AERAQLQgQLQQEREELLARMEAEKEELSEEIAALQQERDEglllaESEKQQALSLKESEKTALSEKLMGTRHSLAAISL 1092
Cdd:COG1196    341 ELEEELE-EAEEELEEAEAELAEAEEALLEAEAELAEAEEE-----LEELAEELLEALRAAAELAAQLEELEEAEEALLE 414

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1093 EMERQKRDAQSRQEQDRntvnALTSELRDLRAQLEEATAAHAQQVKELQEQTGNLGRQREACMREAEELRTQLRLLEDTR 1172
Cdd:COG1196    415 RLERLEEELEELEEALA----ELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAA 490

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1173 dgLRRELLEAQRKVRDSQDSSEAHRQEASELRRSLSEG------TKEREALRRSNEELRTAVKKAESERISLKLANEDKE 1246
Cdd:COG1196    491 --ARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVavligvEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKA 568

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1247 QKLALLEEARMSVAKEAGELRASLQEVERSRLEARRELQELRRQMKTLDSDNGRLGRELADLQSRLALGE-RTEKESRRE 1325
Cdd:COG1196    569 AKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRaVTLAGRLRE 648

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1326 VLGLRQKVLKGESSLEALKQELQGSQRKLQEQEAEFRARERGLLGSLEEARGAEKKLLDSARSLELRLEGVRAETSELGL 1405
Cdd:COG1196    649 VTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEE 728

                          570       580       590
                   ....*....|....*....|....*....|....*....
gi 1958776745 1406 RLSAAEGRAQGLEVELARVEAQRRVAEAQLGGLRSALRR 1444
Cdd:COG1196    729 QLEAEREELLEELLEEEELLEEEALEELPEPPDLEELER 767
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 89-946 1.75e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 92.81  E-value: 1.75e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745   89 QQELSRVEDLLAQSRAERD------ELAIKYNAINERLEQA-VRLETGELEA---------QEPRGLVRQSVELRRQLQE 152
Cdd:TIGR02168  185 RENLDRLEDILNELERQLKslerqaEKAERYKELKAELRELeLALLVLRLEElreeleelqEELKEAEEELEELTAELQE 264

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  153 EQASY----------RRKLQAYQEGQQRQAQLVQRLQAKILQYKKQCSEMEKQLLERSTELEQQRlrdtehsQDLDRALL 222
Cdd:TIGR02168  265 LEEKLeelrlevselEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELE-------SKLDELAE 337

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  223 RLEEEQQRSASLAQVNDMLREQLDQANLANQtlsedickvtsdwtrsckELEQREATWRREEESFNAYFSSEHSRLLLLW 302
Cdd:TIGR02168  338 ELAELEEKLEELKEELESLEAELEELEAELE------------------ELESRLEELEEQLETLRSKVAQLELQIASLN 399

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  303 RQVMGLRRMASEVKMGTERDLLQLGGELVRTSRA----VQEVGLGLSASLQRAESRAEAALEKQKLLQAQLEEQLRAKLL 378
Cdd:TIGR02168  400 NEIERLEARLERLEDRRERLQQEIEELLKKLEEAelkeLQAELEELEEELEELQEELERLEEALEELREELEEAEQALDA 479

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  379 REKDLAQLQVQSDLDKADLSARVTELALSVEHLQNQNTEKDQVNRtLSDKLEALESLRLQEQTTLdtedGEGLQQTLRDL 458
Cdd:TIGR02168  480 AERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGV-LSELISVDEGYEAAIEAAL----GGRLQAVVVEN 554

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  459 AQAALSDTESGVQlsnsertadtsdgsfrGLFGQRTPTPPRHSSPGRGRSPRRGLSPACSDSSTLTLIH-SALHKRQLQV 537
Cdd:TIGR02168  555 LNAAKKAIAFLKQ----------------NELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLvKFDPKLRKAL 618

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  538 QDMRGRYEASQDLLGSVRKQLSDSEGERrgleeqLQRLRDQTATS--VQAQEDAQREAQRLRSANEILsrekgNLSHSLQ 615
Cdd:TIGR02168  619 SYLLGGVLVVDDLDNALELAKKLRPGYR------IVTLDGDLVRPggVITGGSAKTNSSILERRREIE-----ELEEKIE 687

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  616 VAQQQAEDLRQELEKLQAAQEELRRQHTQLEDQQEDTVQEGARARRELERSHRQLEQLEVKRSGLTKELVEVREALSCAV 695
Cdd:TIGR02168  688 ELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELE 767

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  696 LQRDVLQTEKAEVAEALTKAEAGRAQLELSVTKLRAEEASLRDSLskmSALNESLAQDKLELNRLIAQLEEEKAALLGRQ 775
Cdd:TIGR02168  768 ERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAEL---TLLNEEAANLRERLESLERRIAATERRLEDLE 844

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  776 QQAEHATslavEKQERLEQLRLEQEVERQGLEGSLCVAEQAREALGQQILVLRSERSHLQEQVAQLS---RQLNGRDQEL 852
Cdd:TIGR02168  845 EQIEELS----EDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELEskrSELRRELEEL 920

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  853 DQALRESQRQVEALERAAREKEAMAKERAGLAVQLAAAEREGRTLS-----EETIRLRLEKEALESSLFDVQRQLAQLEA 927
Cdd:TIGR02168  921 REKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDeeearRRLKRLENKIKELGPVNLAAIEEYEELKE 1000

                          890
                   ....*....|....*....
gi 1958776745  928 RREQLEADSQALLLAKETL 946
Cdd:TIGR02168 1001 RYDFLTAQKEDLTEAKETL 1019
PTZ00121 PTZ00121
MAEBL; Provisional
 526-1283 6.76e-18

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 90.97  E-value: 6.76e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  526 IHSALHKRQLQVQDMRGRYEASQDLLGSVRKQLSDSEG--ERRGLEEQLQRLRDQTATSVQAQEDAQREAQRLRSANEIl 603
Cdd:PTZ00121  1055 NHEGKAEAKAHVGQDEGLKPSYKDFDFDAKEDNRADEAteEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEA- 1133

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  604 srekgnlshslqvaqQQAEDLRQELEKLQAAQEELRRQHTQLEDQQEDTVQEGARARRELERSHRQLEqleVKRSGltke 683
Cdd:PTZ00121  1134 ---------------RKAEDARKAEEARKAEDAKRVEIARKAEDARKAEEARKAEDAKKAEAARKAEE---VRKAE---- 1191

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  684 lvEVREAlscavlqRDVLQTEKAEVAEALTKAE-AGRAQLELSVTKLRAEEASLRDSlskmsalNESLAQDKLELNRLIA 762
Cdd:PTZ00121  1192 --ELRKA-------EDARKAEAARKAEEERKAEeARKAEDAKKAEAVKKAEEAKKDA-------EEAKKAEEERNNEEIR 1255

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  763 QLEEEKAALLGRQQQAEHAtslavEKQERLEQLRLEQEVERqglegslcvAEQAREAlgqqilvlrSERSHLQEqvAQLS 842
Cdd:PTZ00121  1256 KFEEARMAHFARRQAAIKA-----EEARKADELKKAEEKKK---------ADEAKKA---------EEKKKADE--AKKK 1310

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  843 RQLNGRDQELDQALRESQRQVEALERAAREK----EAMAKERAGLAVQLAAAEREGRTLSEETIRLRLEKEALESSLFDV 918
Cdd:PTZ00121  1311 AEEAKKADEAKKKAEEAKKKADAAKKKAEEAkkaaEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEK 1390

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  919 QR-QLAQLEARREQLEADSQALLLAKETLTGELAGLRQQVTATEE--KAALDKELMTQKLVQAERETQASLREQRAaheE 995
Cdd:PTZ00121  1391 KKaDEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEakKKAEEAKKADEAKKKAEEAKKAEEAKKKA---E 1467

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  996 DLQRLQREKEAAWRELQAERAQLQGQLQQEREELLARMEAEKEELSEEIAALQQERDEGLLLAEsEKQQALSLKESEKTA 1075
Cdd:PTZ00121  1468 EAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAE-EAKKADEAKKAEEKK 1546

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1076 LSEKLMGTRHSLAAisleMERQKRDAQSRQEQDRNTVNALTSELRDL---------------------RAQLEEATAAHA 1134
Cdd:PTZ00121  1547 KADELKKAEELKKA----EEKKKAEEAKKAEEDKNMALRKAEEAKKAeearieevmklyeeekkmkaeEAKKAEEAKIKA 1622

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1135 QQVK---ELQEQTGNLGRQREACMREAEELRTQLRLLEDTRDGLRRELLEAQRKVRDSQDSSEAHRQEASELRRSLSEGT 1211
Cdd:PTZ00121  1623 EELKkaeEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAK 1702

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1958776745 1212 KEREALRRSNEELRTA--VKKAESER-ISLKLANEDKEQKLALLEEARMSvAKEAGELRASLQEVERSRLEARRE 1283
Cdd:PTZ00121  1703 KAEELKKKEAEEKKKAeeLKKAEEENkIKAEEAKKEAEEDKKKAEEAKKD-EEEKKKIAHLKKEEEKKAEEIRKE 1776
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 995-1881 2.83e-17

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 88.97  E-value: 2.83e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  995 EDLQRLQREKEAA--WRELQAERAQLQGQLQQEREELLARmeaekeelseEIAALQQERDEglllaesekqqalslKESE 1072
Cdd:TIGR02169  198 QQLERLRREREKAerYQALLKEKREYEGYELLKEKEALER----------QKEAIERQLAS---------------LEEE 252

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1073 KTALSEKLMGTRHSLAAISLEMERQKRDAQSRQEQDRNTVNALTSELRDLRAQLEEATAAHAQQVKELQEQTGNLGRQRE 1152
Cdd:TIGR02169  253 LEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEID 332

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1153 ACMREAEELRTQLRLLEDTRDGLRRELLEAQRKVRDSQDSSEAHRQEASELRRSLSEGTKEREALRRSNEELRTAVKKAE 1232
Cdd:TIGR02169  333 KLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQ 412

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1233 SERISLKLANEDKEQKLALLEEARMSVAKEAGELRASLQEVERSRLEARRELQELRRQMKTLDSDNGRLGRELADLQSRL 1312
Cdd:TIGR02169  413 EELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQREL 492

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1313 ALGERTEKESRREVLGLRQKVLKGESSLEALkqelQGSQRKLQEQEAEFRArergllgSLEEARGAEKKL------LDSA 1386
Cdd:TIGR02169  493 AEAEAQARASEERVRGGRAVEEVLKASIQGV----HGTVAQLGSVGERYAT-------AIEVAAGNRLNNvvveddAVAK 561

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1387 RSLE------------LRLEGVRAETSELGLrlsAAEGRAQGLEVELARVEAQRRVAEAQLGG-------LRSALRRGLG 1447
Cdd:TIGR02169  562 EAIEllkrrkagratfLPLNKMRDERRDLSI---LSEDGVIGFAVDLVEFDPKYEPAFKYVFGdtlvvedIEAARRLMGK 638

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1448 LGRVSSSPAREAPAGGSGDGLSSPSPLEYSPRSQPPSPGPVASpappdlDPEAVRDALRDFLQELRSAQRERDELRVQTS 1527
Cdd:TIGR02169  639 YRMVTLEGELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRE------RLEGLKRELSSLQSELRRIENRLDELSQELS 712

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1528 TLSQQLAEMEAERDHAASRAKQLQKAVAESEEAWRSADRRLSGAQAELALQEESVRRSRRECRATLDQMAVLERSLqate 1607
Cdd:TIGR02169  713 DASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARL---- 788

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1608 selraSQEKVNKMKATEVKLESDKRRLKEVLDASESRSIKLELQRRALEGELQrsrlglgDREAHAQALQDRVDSLQRQV 1687
Cdd:TIGR02169  789 -----SHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQ-------ELQEQRIDLKEQIKSIEKEI 856

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1688 ADSEVKAGTLQLTVERLSGALAKVEESEGTLRSKVQSLTDALAQssasltssqdknlyLQKALSTCEHDRQVLQERLDAA 1767
Cdd:TIGR02169  857 ENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRE--------------LERKIEELEAQIEKKRKRLSEL 922

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1768 RQALSEARRQSSSLGEQVQTLRGELANLElqrgDAEGQLQQLQQVLRQRQEGEAVALRSVQKLQEErrllQERLGSLQRA 1847
Cdd:TIGR02169  923 KAKLEALEEELSEIEDPKGEDEEIPEEEL----SLEDVQAELQRVEEEIRALEPVNMLAIQEYEEV----LKRLDELKEK 994

                          890       900       910
                   ....*....|....*....|....*....|....*
gi 1958776745 1848 LAQLEAEKRELERSALQLD-KDRVALRKTLDKVER 1881
Cdd:TIGR02169  995 RAKLEEERKAILERIEEYEkKKREVFMEAFEAINE 1029
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 657-1442 3.18e-17

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 88.59  E-value: 3.18e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  657 ARARRELERSHRQLEQLEVKRSGLTKELVEVREALSCAvLQRDVLQTEKAEVA--EALTKAEAGRAQLElsvtKLRAEEA 734
Cdd:TIGR02169  173 EKALEELEEVEENIERLDLIIDEKRQQLERLRREREKA-ERYQALLKEKREYEgyELLKEKEALERQKE----AIERQLA 247

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  735 SLRDSLSKMSALNESLAQDKLELNRLIAQLEEEKAALLGRQQqaehatslaVEKQERLEQLrleqEVERQGLEGSLCVAE 814
Cdd:TIGR02169  248 SLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQ---------LRVKEKIGEL----EAEIASLERSIAEKE 314

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  815 QAREALGQQILVLRSERSHLQEQVAQLSRQlngrdqeldqaLRESQRQVEALERAAREKEAmakERAGLAVQLAAAEREG 894
Cdd:TIGR02169  315 RELEDAEERLAKLEAEIDKLLAEIEELERE-----------IEEERKRRDKLTEEYAELKE---ELEDLRAELEEVDKEF 380

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  895 RTLSEETIRLRLEKEALESSLFDVQRQLAQLEARREQLeadSQALLLAKETLTGELAGLRQQVTATEEKAALDKELmTQK 974
Cdd:TIGR02169  381 AETRDELKDYREKLEKLKREINELKRELDRLQEELQRL---SEELADLNAAIAGIEAKINELEEEKEDKALEIKKQ-EWK 456

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  975 LVQAeRETQASLREQRAAHEEDLQRLQREKEAAWRELQAERAQLQGQLQQEREEllarmeaekeelseeiAALQQERDEG 1054
Cdd:TIGR02169  457 LEQL-AADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGG----------------RAVEEVLKAS 519

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1055 LLLAESEKQQALSLKESEKTALsEKLMGTRhsLAAISLEMERQKRDA---QSRQEQDRNT---VNALTSELRDLRAQLEE 1128
Cdd:TIGR02169  520 IQGVHGTVAQLGSVGERYATAI-EVAAGNR--LNNVVVEDDAVAKEAielLKRRKAGRATflpLNKMRDERRDLSILSED 596

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1129 ATAAHAQQVKELQEQTGNLGRQREACMREAEELRTQLRLLEDTR-DGLRRELLE-------AQRKVRDSQDSSEAHRQEA 1200
Cdd:TIGR02169  597 GVIGFAVDLVEFDPKYEPAFKYVFGDTLVVEDIEAARRLMGKYRmVTLEGELFEksgamtgGSRAPRGGILFSRSEPAEL 676

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1201 SELRRSLSEGTKEREALRRSNEELRTAVKKAESERISLKLANEDKEQKLALLEEARMSVAKEAGELRASLQEVERSRLEA 1280
Cdd:TIGR02169  677 QRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENV 756

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1281 RRELQELRRQMKTLDSDNGRLGRELADLQSRLA---------LGERTEKESRREVLGLR------QKVLKGESSLEALKQ 1345
Cdd:TIGR02169  757 KSELKELEARIEELEEDLHKLEEALNDLEARLShsripeiqaELSKLEEEVSRIEARLReieqklNRLTLEKEYLEKEIQ 836

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1346 ELQGSQRKLQEQEAEFRARERGLLGSLEEARGAEKKLLDSARSLELRLEGVRAETSELGLRLSAAEGRAQGLEVELARVE 1425
Cdd:TIGR02169  837 ELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKR 916

                          810
                   ....*....|....*..
gi 1958776745 1426 AQRRVAEAQLGGLRSAL 1442
Cdd:TIGR02169  917 KRLSELKAKLEALEEEL 933
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1264-1956 9.86e-17

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 86.91  E-value: 9.86e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1264 GELRASLQEVERSRLEARReLQELRRQMKTLDSDngRLGRELADLQSRLALGERTEKESRREVLGLRQKVLKGESSLEAL 1343
Cdd:COG1196    196 GELERQLEPLERQAEKAER-YRELKEELKELEAE--LLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEEL 272

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1344 KQELQgsqrKLQEQEAEFRARERGLLGSLEEARGAEKKLLDSARSLELRLEGVRAETSELGLRLSAAEGRAQGLEVELAR 1423
Cdd:COG1196    273 RLELE----ELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEE 348

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1424 VEAQRRVAEAQLgglrsalrrglglgrvssspareapaggsgdglsspspleysprsqppspgpvaspappdldpEAVRD 1503
Cdd:COG1196    349 AEEELEEAEAEL---------------------------------------------------------------AEAEE 365

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1504 ALRDFLQELRSAQRERDELRVQTSTLSQQLAEMEAERDHAASRAKQLQKAVAESEEAWRSADRRLSGAQAELALQEESVR 1583
Cdd:COG1196    366 ALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALE 445

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1584 RSRRECRATLDQMAVLERSLQATESELRASQEKVNKMKATEVKLESDKRRLKEVLDASE--SRSIKLELQRRALEGELQR 1661
Cdd:COG1196    446 EAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEgfLEGVKAALLLAGLRGLAGA 525

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1662 SRLGLGDREAHAQALQDRVdslqrqvadsevkAGTLQLTVERLSGALAKVEESEGTLRSKVQSLTDALAQSSASLTSSQD 1741
Cdd:COG1196    526 VAVLIGVEAAYEAALEAAL-------------AAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAAL 592

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1742 KNLYLQKALSTCEHDRQVLQERLDAARQALSEARRQSSSLGEQVQTLRGELANLELQRGDAEGQLQQLQQVLRQRQEGEA 1821
Cdd:COG1196    593 ARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLA 672

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1822 VALRSVQKLQEERRLLQERLGSLQRALAQLEAEKRELERSALQLDKDRVALRKTLDKVEREKLRSHEDTLRLNAERGRLD 1901
Cdd:COG1196    673 ALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEA 752

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1958776745 1902 RTLTGAELDLAEAQQQIQHLEAQVvevleRNHSPVQVEADEQHLELQQEVERLRS 1956
Cdd:COG1196    753 LEELPEPPDLEELERELERLEREI-----EALGPVNLLAIEEYEELEERYDFLSE 802
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1070-1882 3.51e-16

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 85.12  E-value: 3.51e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1070 ESEKTALSEKLMGTRHSLAAISLeMERQKRDAQSRQEQDRNTvnalTSELRDLRAQLEEATA-AHAQQVKELQEQTGNLG 1148
Cdd:TIGR02169  169 DRKKEKALEELEEVEENIERLDL-IIDEKRQQLERLRREREK----AERYQALLKEKREYEGyELLKEKEALERQKEAIE 243

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1149 RQREACMREAEELRTQLRLLEDTRDGLRRELLEAQRKVRDSQDsseahrQEASELRRSLSEGTKEREALRRSNEELRTAV 1228
Cdd:TIGR02169  244 RQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGE------EEQLRVKEKIGELEAEIASLERSIAEKEREL 317

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1229 KKAESERI--------------SLKLANEDKEQKLALLEEARMSVAKEAGELRASLQEVERSRLEARRELQELRRQMKTL 1294
Cdd:TIGR02169  318 EDAEERLAkleaeidkllaeieELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKL 397

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1295 DSDNGRLGRELADLQSRLALGERTEKESRREVLGLRQKVLKGESSLEALKQELQGSQRKLQEQEAEFRARERGLLGSLEE 1374
Cdd:TIGR02169  398 KREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEE 477

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1375 ARGAEKKLLDSARSLELRLEGVRAETSELGLRLSAAEGRAQGLEVELARVEAQRRVAEAQLGGLRSALRRGLGLGRVSS- 1453
Cdd:TIGR02169  478 YDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEVAAGNRLNNVVVEDd 557

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1454 SPAREAPAGGSGDGLSSPSPLEYSPRSQPPSPGPVASPAPP--------DLDPE---AVRDALRDFL--QELRSAQRERD 1520
Cdd:TIGR02169  558 AVAKEAIELLKRRKAGRATFLPLNKMRDERRDLSILSEDGVigfavdlvEFDPKyepAFKYVFGDTLvvEDIEAARRLMG 637

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1521 ELRVqtSTLSQQLAEMEAERDHAASRAKQLQKAVAESEEAWRSADRRLSGAQAELALQEESVRRSRRECRATLDQMAVLE 1600
Cdd:TIGR02169  638 KYRM--VTLEGELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDAS 715

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1601 RSLQATESELRAsqekvnkmkatevkLESDKRRLKEVLDASESRSIKLELQRRALEGELQRSRLGLGDREAHAQALQDRV 1680
Cdd:TIGR02169  716 RKIGEIEKEIEQ--------------LEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEAL 781

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1681 DSLQRQVADSEVKagtlqltverlsgalaKVEESEGTLRSKVQSLTDALAQSSASLTSSQDKNLYLQKALSTCEHDRQVL 1760
Cdd:TIGR02169  782 NDLEARLSHSRIP----------------EIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDL 845

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1761 QERLDAARQALSEARRQSSSLGEQVQTLRGELANLELQRGDAEGQLQQLQQVLRQRQEGEAVALRSVQKLQEERRLLQER 1840
Cdd:TIGR02169  846 KEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAK 925

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|..
gi 1958776745 1841 LGSLQRALAQLEAEKRELERSALQLDKDRVaLRKTLDKVERE 1882
Cdd:TIGR02169  926 LEALEEELSEIEDPKGEDEEIPEEELSLED-VQAELQRVEEE 966
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 815-1618 4.08e-16

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 85.11  E-value: 4.08e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  815 QAREAlgQQILVLRSERSHLQEQVAQLS-RQLNGRDQELDQALRESQRQVEALERAAREKEA----MAKERAGLAVQLAA 889
Cdd:TIGR02168  208 QAEKA--ERYKELKAELRELELALLVLRlEELREELEELQEELKEAEEELEELTAELQELEEkleeLRLEVSELEEEIEE 285

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  890 AEREGRTLSEETIRLRLEKEALESSLFDVQRQLAQLEARREQLEADSQALLLAKETLTGELAGLRQQVTATEEKAaldke 969
Cdd:TIGR02168  286 LQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAEL----- 360

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  970 lmtqklvqaeretqaslrEQRAAHEEDLQRLQREKEAAWRELQAERAQLQGQLQQEREELlARMEAEKEELSEEIAALQQ 1049
Cdd:TIGR02168  361 ------------------EELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEI-ERLEARLERLEDRRERLQQ 421

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1050 ERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLAAISLEMERQKRDAQSRQEQDRNTVNALTSE---LRDLRAQL 1126
Cdd:TIGR02168  422 EIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARldsLERLQENL 501

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1127 EEATAAHAQQVKELQEQTGNLGRQRE----------------------ACMREAEELRTQLRLLEDTRDGLRRELLEAQR 1184
Cdd:TIGR02168  502 EGFSEGVKALLKNQSGLSGILGVLSElisvdegyeaaieaalggrlqaVVVENLNAAKKAIAFLKQNELGRVTFLPLDSI 581

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1185 KVRDSQDSSEAHRQEASELRRSLSEGTKEREALRRSNEELRTAVKKAESERISLKLANEDKEQKLALLEE-----ARMSV 1259
Cdd:TIGR02168  582 KGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKKLRPGYRIVTLDgdlvrPGGVI 661

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1260 AKEAGELRASlqeversRLEARRELQELRRQMKTLDSDNGRLGRELADLQSRLALGERTEKESRREVLGLRQKVLKGESS 1339
Cdd:TIGR02168  662 TGGSAKTNSS-------ILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKD 734

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1340 LEALKQELQGSQRKLQEQE---AEFRARERGLLGSLEEARGAEKKLLDSARSLELRLEGVRAETSELGLRLSAAEGRAQG 1416
Cdd:TIGR02168  735 LARLEAEVEQLEERIAQLSkelTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTL 814

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1417 LEVELARVEAQRRVAEAQLGGLRsalrrglglgrvssspareapaggsgdglsspspleysprsqppspgpvaspappdl 1496
Cdd:TIGR02168  815 LNEEAANLRERLESLERRIAATE--------------------------------------------------------- 837

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1497 dpeavrdalrdflQELRSAQRERDELRVQTSTLSQQLAEMEAERDHAASRAKQLQKAVAESEEAWRSADRRLSGAQAELA 1576
Cdd:TIGR02168  838 -------------RRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELR 904

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|..
gi 1958776745 1577 LQEESVRRSRRECRATLDQMAVLERSLQATESELRASQEKVN 1618
Cdd:TIGR02168  905 ELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLS 946
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1181-1984 1.96e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 82.80  E-value: 1.96e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1181 EAQRKVRDSQDSSEAHRQEASELRR---SLSEGTKEREALRRSNEELRTAvkkaesERISLKLANEDKEQKLALLEEARM 1257
Cdd:TIGR02168  176 ETERKLERTRENLDRLEDILNELERqlkSLERQAEKAERYKELKAELREL------ELALLVLRLEELREELEELQEELK 249

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1258 SVAKEAGELRASLQEVERSRLEARRELQELRRQMKTLDSDNGRLGRELADLQSRLALGERTEKESRREVLGLRQKVLKGE 1337
Cdd:TIGR02168  250 EAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELE 329

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1338 SSLEALKQELQGSQRKLQEQEAEFRArergLLGSLEEARGAEKKLLDSARSLELRLEGVRAETSELGLRLSAAEGRAQGL 1417
Cdd:TIGR02168  330 SKLDELAEELAELEEKLEELKEELES----LEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERL 405

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1418 EVELARVEAQRRVAEAQLGGLRSALrrglglgrvsSSPAREAPAGGSGDGLSSPSPLEysprsqppspgpvaspappdLD 1497
Cdd:TIGR02168  406 EARLERLEDRRERLQQEIEELLKKL----------EEAELKELQAELEELEEELEELQ--------------------EE 455

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1498 PEAVRDALRDFLQELRSAQRERDELRVQTSTLSQQLAEMEAERDHAASRAKQLQKAVAESEEAWRSADRRLSG--AQAEL 1575
Cdd:TIGR02168  456 LERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELisVDEGY 535

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1576 ALQEESVRRSRREcratldqmAVLERSLQATESELrASQEKVNKMKATEVKLESDKRRLKEVLDASESRSIKLELQ---- 1651
Cdd:TIGR02168  536 EAAIEAALGGRLQ--------AVVVENLNAAKKAI-AFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGvakd 606

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1652 --------RRALEGELQRSRLGlgDREAHAQALQDRVDSLQRQVadseVKAGTLQLTVERLSGALAKVEESEGTLRSKVQ 1723
Cdd:TIGR02168  607 lvkfdpklRKALSYLLGGVLVV--DDLDNALELAKKLRPGYRIV----TLDGDLVRPGGVITGGSAKTNSSILERRREIE 680

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1724 SLTDALAQSSASLTSSQDKNLYLQKALSTCEHDRQVLQERLDAARQALSEARRQSSSLGEQVQTLRGELANLELQRGDAE 1803
Cdd:TIGR02168  681 ELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELE 760

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1804 GQLQQLQQVLRQRQEGEAVALRSVQKLQEERRLLQERLGSLQRALAQLEAEKRELERSALQLDKDRVALRKTLDKVEREK 1883
Cdd:TIGR02168  761 AEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRL 840

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1884 LRSHEDTLRLNAERGRLDRTLTGAELDLAEAQQQIQHLEAQVVEVLERNHspvqvEADEQHLELQQEVERLRSAQVRTER 1963
Cdd:TIGR02168  841 EDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALA-----LLRSELEELSEELRELESKRSELRR 915

                          810       820
                   ....*....|....*....|....
gi 1958776745 1964 TLEA---RERAHRQRVSGLEEQVQ 1984
Cdd:TIGR02168  916 ELEElreKLAQLELRLEGLEVRID 939
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 89-684 8.30e-15

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 80.75  E-value: 8.30e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745   89 QQELSRVEDLLAQSRAERDEL------AIKYNAINERLEQAvrletgeleaqeprgLVRQSVELRRQLQEEQASYRRKLQ 162
Cdd:COG1196    185 EENLERLEDILGELERQLEPLerqaekAERYRELKEELKEL---------------EAELLLLKLRELEAELEELEAELE 249

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  163 AYQEGQQRQAQLVQRLQAKILQYKKQCSEMEKQLLERSTELEQQRLRDTEHSQDLDRALLRLEEEQQRSASLAQVNDMLR 242
Cdd:COG1196    250 ELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELE 329

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  243 EQLDQANLANQTLSEDICKVTSDWTRSCKELEQREATWRREEESFNAyfssEHSRLLLLWRQVMGLRRMASEVKMGTERD 322
Cdd:COG1196    330 EELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAE----AEEELEELAEELLEALRAAAELAAQLEEL 405

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  323 LLQLGGELVRTSRAVQEVGLGLSASLQRAESRAEAALEKQKLLQAQLEEQLRAKLLREKDLAQLQVQSDLDK--ADLSAR 400
Cdd:COG1196    406 EEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAalAELLEE 485

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  401 VTELALSVEHLQNQNTEKDQVNRTLSDKLEALESLRLQEQTTLDTEDGEGLQQTLRDLAQAAL-----SDTESGVQLSNS 475
Cdd:COG1196    486 LAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALqnivvEDDEVAAAAIEY 565

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  476 ERTADTSDGSFRGLFGQRTPTPPRHSSPGRGRSPRRGL--SPACSDSSTLTLIHSALHKRQLQVQDMRGRYEASQDLLGS 553
Cdd:COG1196    566 LKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLvaSDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGR 645

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  554 VRKQLSDSEGERRGLEEQLQRLRDQTATSVQAQEDAQREAQRLRSANEILSREKGNLSHSLQVAQQQAEDLRQELEKLQA 633
Cdd:COG1196    646 LREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEA 725

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1958776745  634 AQEELRRQHTQLEDQQEDTVQEGARARRELERSHRQLEQLEVKRSGLTKEL 684
Cdd:COG1196    726 LEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREI 776
PTZ00121 PTZ00121
MAEBL; Provisional
 544-1321 8.70e-15

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 80.96  E-value: 8.70e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  544 YEASQDLLGSVRKQLSDSEGERRGLEEQLQRLRD-QTATSVQAQEDAQR--EAQRLRSANEILSREKGNLSHSLQVAQQ- 619
Cdd:PTZ00121  1093 TEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDaRKAEEARKAEDARKaeEARKAEDAKRVEIARKAEDARKAEEARKa 1172

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  620 ----QAEDLRQELEKLQAAQ----EELRRQHTQLEDQQEDTVQEGARAR--------RELERSHRQLEqlEVKRSGLTKE 683
Cdd:PTZ00121  1173 edakKAEAARKAEEVRKAEElrkaEDARKAEAARKAEEERKAEEARKAEdakkaeavKKAEEAKKDAE--EAKKAEEERN 1250

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  684 LVEVRE----ALSCAVLQRDVLQTEKAEVAEALTKAEAGRAQLEL--SVTKLRAEEASLR-DSLSKMSALNESLAQDKLE 756
Cdd:PTZ00121  1251 NEEIRKfeeaRMAHFARRQAAIKAEEARKADELKKAEEKKKADEAkkAEEKKKADEAKKKaEEAKKADEAKKKAEEAKKK 1330

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  757 LNRLIAQLEEEKAALLGRQQQAEHATSLAVEKQERLEQLRLEQEVERQGLEGSLCVAEQAREAlgQQILVLRSERSHLQE 836
Cdd:PTZ00121  1331 ADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKA--DEAKKKAEEDKKKAD 1408

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  837 QVAQLSRQLNGRDQELDQAlrESQRQVEALERAAREKEAmAKERAGLAVQLAAAEREGRTLSEETIRLRLEKEALESSLF 916
Cdd:PTZ00121  1409 ELKKAAAAKKKADEAKKKA--EEKKKADEAKKKAEEAKK-ADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKA 1485

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  917 D-VQRQLAQLEARREQLEADSQALLLAKETLTGELAGLRQQVTATEEKAALDKELMTQKLVQAERETQAslrEQRAAHEE 995
Cdd:PTZ00121  1486 DeAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKA---EELKKAEE 1562

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  996 DLQRLQREKEAAWRELQAERAQLQGQLQQEREELLARMEAEKeelseeiaalQQERDEGLLLAESEKQQALSLKESEKTA 1075
Cdd:PTZ00121  1563 KKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEE----------KKMKAEEAKKAEEAKIKAEELKKAEEEK 1632

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1076 LSEKLMGTRhslaaislEMERQKRDAQSRQEQDRNTVNAltsELRDLRAQLEEATAAHAQQVKELQEQTGNLGRQREACM 1155
Cdd:PTZ00121  1633 KKVEQLKKK--------EAEEKKKAEELKKAEEENKIKA---AEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEA 1701

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1156 REAEELRTQLRLLEDTRDGLRRELLEAQRKVRDSQDSSEAHRQEASELRRslSEGTKEREALRRSNEELRTAVKKAESER 1235
Cdd:PTZ00121  1702 KKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKK--DEEEKKKIAHLKKEEEKKAEEIRKEKEA 1779

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1236 ISLKLANEDKEQKLALLEE------ARMSVAKEAGE------------LRASLQEVERSRLEARRELQELRRQMKTLDSD 1297
Cdd:PTZ00121  1780 VIEEELDEEDEKRRMEVDKkikdifDNFANIIEGGKegnlvindskemEDSAIKEVADSKNMQLEEADAFEKHKFNKNNE 1859

                          810       820
                   ....*....|....*....|....
gi 1958776745 1298 NGRLGRELADLQSRLALGERTEKE 1321
Cdd:PTZ00121  1860 NGEDGNKEADFNKEKDLKEDDEEE 1883
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1511-2002 8.80e-15

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 80.37  E-value: 8.80e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1511 ELRSAQRERDELRVQTSTLSQQLAEMEAERDHAASRAKQLQKAVAESEEAWRSADRRLSGAQAELALQEESVRRSRRECR 1590
Cdd:COG1196    226 EAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIA 305

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1591 ATLDQMAVLERSLQATESELRASQEKVNKMKATEVKLESDKRRLKEVLDASESRSIKLELQRRALEGELQRSRLGLGDRE 1670
Cdd:COG1196    306 RLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELA 385

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1671 AHAQALQDRVDSLQRQVADSEVKAGTLQLTVERLSGALAKVEESEGTLRSKVQSLTDALAQSSASLTSSQDKNLYLQKAL 1750
Cdd:COG1196    386 EELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELL 465

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1751 STCEHDRQVLQERLDAARQALSEARRQSSSLGEQVQTLRGELA-------NLELQRGDAEGQLQQLQQVLRQRQEGEAVA 1823
Cdd:COG1196    466 AELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEgvkaallLAGLRGLAGAVAVLIGVEAAYEAALEAALA 545

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1824 LRSVQKLQEERRLLQERLGSLQRA---------LAQLEAEKRELERSALQLDKDRVALRKTLDKVEREKLRSHEDTL--- 1891
Cdd:COG1196    546 AALQNIVVEDDEVAAAAIEYLKAAkagratflpLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLlgr 625

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1892 -----------RLNAERGRLDRTLTGAELDLAEAQQQIQHLEAQVVEVLERNHSPVQVEADEQHLELQQEVERLRSAQVR 1960
Cdd:COG1196    626 tlvaarleaalRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEE 705

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|..
gi 1958776745 1961 TERTLEARERAHRQRVSGLEEQVQGPFLREGAGMELWGWRED 2002
Cdd:COG1196    706 ERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEEL 747
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1139-1858 1.63e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 79.60  E-value: 1.63e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1139 ELQEQTGNLGRQREACmREAEELRTQLRLLEDTRDGLRRELLEAQRKVRDSQdsSEAHRQEASELRRSLSEGTKEREALR 1218
Cdd:COG1196    197 ELERQLEPLERQAEKA-ERYRELKEELKELEAELLLLKLRELEAELEELEAE--LEELEAELEELEAELAELEAELEELR 273

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1219 RSNEELRTAVKKAESERISLKLANEDKEQKLALLEEARMSVAKEAGELRASLQEVERSRLEARRELQELRRQMKTLDSDN 1298
Cdd:COG1196    274 LELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEEL 353

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1299 GRLGRELADLQSRLALGERTEKESRREVLGLRQKVLKGESSLEALKQELQGSQRKLQEQE---AEFRARERGLLGSLEEA 1375
Cdd:COG1196    354 EEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLerlERLEEELEELEEALAEL 433

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1376 RGAEKKLLDSARSLELRLEGVRAETSELGLRLSAAEGRAQGLEVELARVEAQRRVAEAQLGGLRSALRRGLGLGRVSSSP 1455
Cdd:COG1196    434 EEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAA 513

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1456 AREAPAGGSGDGLsspspleysprsqppspgpvaspAPPDLDPEAVRDALRDFLQELRSAQRERDELRVQtstlsqqlAE 1535
Cdd:COG1196    514 LLLAGLRGLAGAV-----------------------AVLIGVEAAYEAALEAALAAALQNIVVEDDEVAA--------AA 562

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1536 MEAERDHAASRAKQLQKAVAESEEAWRSADRRLSGAQAELALQEESVRRSRRecrATLDQMAVLERSLQATESELRASQE 1615
Cdd:COG1196    563 IEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADAR---YYVLGDTLLGRTLVAARLEAALRRA 639

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1616 KVNKMKATEVKLESDKRRLKEVLDASESRSIKLELQRRALEGELQRSRLGlgDREAHAQALQDRVDSLQRQVADSEVKAG 1695
Cdd:COG1196    640 VTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLA--EEELELEEALLAEEEEERELAEAEEERL 717

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1696 TLQLTVERLSGALAKVEESEGTLRSKVQSLTDALAQSSASLtssqdknlylqkalstcEHDRQVLQERLDAARQALSEar 1775
Cdd:COG1196    718 EEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPE-----------------PPDLEELERELERLEREIEA-- 778

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1776 rqsssLG-------EQVQTLRGELANLELQRGDaegqlqqlqqvlrqrqegeavalrsvqklqeerrlLQERLGSLQRAL 1848
Cdd:COG1196    779 -----LGpvnllaiEEYEELEERYDFLSEQRED-----------------------------------LEEARETLEEAI 818

                          730
                   ....*....|
gi 1958776745 1849 AQLEAEKREL 1858
Cdd:COG1196    819 EEIDRETRER 828
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1510-1984 5.92e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 77.67  E-value: 5.92e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1510 QELRSAQRERDELRVQTSTLSQQLAEMEAERDHAASRAKQLQKAVAESEEAWRSADRRLSGAQAELALQEESVRRSRREC 1589
Cdd:COG1196    309 ERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEEL 388

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1590 RATLDQMAVLERSLQATESELRASQEKVNKMKATEVKLESDKRRLKEVLDASESRSIKLELQRRALEGELQRSRLGLGDR 1669
Cdd:COG1196    389 LEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAEL 468

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1670 EAHAQALQDRVDSLQRQVADSEVKAGTLQLTVERLSGALAKVEESEG-TLRSKVQSLTDALAQSSASLTSSQDKNLYLQK 1748
Cdd:COG1196    469 LEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLlAGLRGLAGAVAVLIGVEAAYEAALEAALAAAL 548

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1749 ALSTCEHDRQVLQERLDAARQALSEARRQSSSLGEQVQTLRGELANLELQRGDAEGQLQQLQQVLRQRQEGEAVALRSVQ 1828
Cdd:COG1196    549 QNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLV 628

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1829 KLQEERRLLQERLGSLQRALAQLEAEKRELERSALQLDKDRVALRKTLDKVEREKLRSHEDTLRLNAERGRLDRTLTGAE 1908
Cdd:COG1196    629 AARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERE 708

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958776745 1909 LDLAEAQQQIQHLEAQVVEVLERnhspvqvEADEQHLELQQEVERLRSAQVRTERTLEARERAHRQRVSGLEEQVQ 1984
Cdd:COG1196    709 LAEAEEERLEEELEEEALEEQLE-------AEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIE 777
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 81-821 9.10e-14

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 77.40  E-value: 9.10e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745   81 LQEENQLLQQELSRVEDLLAQSRAERDELAIKYNAINERLEQAV-RLETGELEAQEPRGLVRQSVELRRQLQEEQASYRR 159
Cdd:TIGR02168  286 LQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELEsKLDELAEELAELEEKLEELKEELESLEAELEELEA 365

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  160 KLQAYQEGQQRQAQLVQRLQAKILQYKKQCSEMEKQLLERSTELEQ-----QRLRDTEHSQDLDRALLRLEEEQQRSASL 234
Cdd:TIGR02168  366 ELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERledrrERLQQEIEELLKKLEEAELKELQAELEEL 445

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  235 AQVNDMLREQLDQANLANQTLSEDIckvtsdwtrscKELEQREATWRREEESFNAYFSSEHSRLlllwRQVMGLRRMASE 314
Cdd:TIGR02168  446 EEELEELQEELERLEEALEELREEL-----------EEAEQALDAAERELAQLQARLDSLERLQ----ENLEGFSEGVKA 510

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  315 VKMgterDLLQLGGelvrtsravqevGLGLSASLQRAESRAEAALEkqkllqAQLEEQLRAKLLREKDLAQLQVQSDLDK 394
Cdd:TIGR02168  511 LLK----NQSGLSG------------ILGVLSELISVDEGYEAAIE------AALGGRLQAVVVENLNAAKKAIAFLKQN 568

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  395 AdlSARVTELALSVehlqnqntEKDQVNRtlSDKLEALESLRLQEQTTLDTEdgeglqqTLRDLAQAALSDTESGVQLSN 474
Cdd:TIGR02168  569 E--LGRVTFLPLDS--------IKGTEIQ--GNDREILKNIEGFLGVAKDLV-------KFDPKLRKALSYLLGGVLVVD 629

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  475 SERTADTSDGSFRGLFGQRTPTPPRHSSPGR--GRSPRRGLSPACSDS------STLTLIHSALHKRQLQVQDMRGRYEA 546
Cdd:TIGR02168  630 DLDNALELAKKLRPGYRIVTLDGDLVRPGGVitGGSAKTNSSILERRReieeleEKIEELEEKIAELEKALAELRKELEE 709

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  547 SQDLLGSVRKQLSDSEGERRGLEEQLQRLRDQTATSVQAQEDAQREAQRLRSANEILSREKGNLSHSLQVAQQQAEDLRQ 626
Cdd:TIGR02168  710 LEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEA 789

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  627 ELEKLQAAQEELRRQHTQLEDQQEDTVQEGARARRELERSHRQLEQLEVKRSGLTKELVEVREALSCAVLQRDVLQTEKA 706
Cdd:TIGR02168  790 QIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIE 869

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  707 EVAEALTKAEAGRAQLELSVTKLRAEEASLRDSLSKMSALNESLAQDKLELNRLIAQLEEEKAALLGR-QQQAEHATSLA 785
Cdd:TIGR02168  870 ELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRiDNLQERLSEEY 949

                          730       740       750
                   ....*....|....*....|....*....|....*.
gi 1958776745  786 VEKQERLEQLRLEQEVERQGLEGSLCVAEQAREALG 821
Cdd:TIGR02168  950 SLTLEEAEALENKIEDDEEEARRRLKRLENKIKELG 985
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1499-2003 2.04e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 76.13  E-value: 2.04e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1499 EAVRDALRDFLQELRSAQRERDELRVQTSTLSQQLAEMEAERDHAASRAKQLQKAVAESEEAWRSADRRLSGAQAELALQ 1578
Cdd:COG1196    263 AELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEEL 342

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1579 EESVRRSRRECRATLDQMAVLERSLQATESELRASQEKVNKMKATEVKLESDKRRLKEVLDASESRSIKLELQRRALEGE 1658
Cdd:COG1196    343 EEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEE 422

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1659 LQRSRLGLGDREAHAQALQDRVDSLQRQVADSEVKAGTLQLTVERLSGALAKVEESEGTLRSKVQsltDALAQSSASLTS 1738
Cdd:COG1196    423 LEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELA---EAAARLLLLLEA 499

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1739 SQDKNLYLQKALstcehdRQVLQERLDAARQALSEARRQSSSLGEQVQTLRGELANLELQRGDAEGQLQQLQQVLRQRQE 1818
Cdd:COG1196    500 EADYEGFLEGVK------AALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGR 573

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1819 GEAVALRSVQKLQEERRLLQERLGSLQRALAQLEAEKRELERSALQ-------LDKDRVALRKTLDKVEREKLRSHEDTL 1891
Cdd:COG1196    574 ATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGdtllgrtLVAARLEAALRRAVTLAGRLREVTLEG 653

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1892 RLNAERGRLDRTLTGAELDLAEAQQQIQHLEAQVVEVLERNHSPVQVEADEQHLELQQEVERLRSAQVRTERTLEARERA 1971
Cdd:COG1196    654 EGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAE 733

                          490       500       510
                   ....*....|....*....|....*....|..
gi 1958776745 1972 HRQRVSGLEEQVQGPFLREGAGMELWGWREDW 2003
Cdd:COG1196    734 REELLEELLEEEELLEEEALEELPEPPDLEEL 765
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1648-1983 5.44e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 74.59  E-value: 5.44e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1648 LELQRRALEGELQRSRLGLGDREAHAQALQDRVDSLQRQVADSEVKAGTLQLTVERLSGALAKVEESEGTLRSKVQSLTD 1727
Cdd:COG1196    216 RELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLA 295

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1728 ALAQSSASLTSSQDKNLYLQKALSTCEHDRQVLQERLDAARQALSEARRQSSSLGEQVQTLRGELANLELQRGDAEGQLQ 1807
Cdd:COG1196    296 ELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELA 375

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1808 QLQQVLRQRQEGEAVALRSVQKLQEERRLLQERLGSLQRALAQLEAEKRELERSALQLDKDRVALRKTLDKVEREKLRSH 1887
Cdd:COG1196    376 EAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELE 455

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1888 EDTLRLNAERGRLDRTLTGAE-------LDLAEAQQQIQHLEAQVVEVLERNHSPVQVEADEQHLELQQEVERLRSAQVR 1960
Cdd:COG1196    456 EEEEALLELLAELLEEAALLEaalaellEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAA 535

                          330       340
                   ....*....|....*....|...
gi 1958776745 1961 TERTLEARERAHRQRVSGLEEQV 1983
Cdd:COG1196    536 YEAALEAALAAALQNIVVEDDEV 558
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 555-1406 7.55e-13

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 74.33  E-value: 7.55e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  555 RKQLSDSEGERRGLEEQLQRLrdqtatSVQAQEDAQREAQRLRSANEILSREKGNLSHSLQVAQQQAEDLRQELEKLQAA 634
Cdd:TIGR02169  236 ERQKEAIERQLASLEEELEKL------TEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERS 309

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  635 QEELRRQHTQLEDQQEDTVQEGARARRELERSHRQLEQLEVKRSGLTKELVEVREalscavlQRDVLQTEKAEVAEALTK 714
Cdd:TIGR02169  310 IAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKE-------ELEDLRAELEEVDKEFAE 382

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  715 AEAGRAQLELSVTKLRAEEASLRDSLSKMSALNESLAQDKLELNRLIAQLEEEKAALlgrqqqaehatslavekQERLEQ 794
Cdd:TIGR02169  383 TRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINEL-----------------EEEKED 445

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  795 LRLEQEVERQglegslcvaeqarealgqqilvlrsERSHLQEQVAQLSRQLngrdqeldQALRESQRQVEaleraareke 874
Cdd:TIGR02169  446 KALEIKKQEW-------------------------KLEQLAADLSKYEQEL--------YDLKEEYDRVE---------- 482

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  875 amaKERAGLAVQLAAAEREGRTLSEETIRLRLEKEALESSLFDVQRQLAQLEARREQLEAdsqalllAKETLTGelAGLR 954
Cdd:TIGR02169  483 ---KELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERYAT-------AIEVAAG--NRLN 550

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  955 QQVTATEEKAALDKELMtqKLVQAERETQASLREQRAAHEE--------------DLQRLQREKEAAWRELQAERAQLQG 1020
Cdd:TIGR02169  551 NVVVEDDAVAKEAIELL--KRRKAGRATFLPLNKMRDERRDlsilsedgvigfavDLVEFDPKYEPAFKYVFGDTLVVED 628

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1021 QLQQEREELLARMEAEkeelseeiaalqqerdEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLAAISLEMERQKRD 1100
Cdd:TIGR02169  629 IEAARRLMGKYRMVTL----------------EGELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSS 692

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1101 AQSRQEQDRNTVNALTSELRDLRAQLEEATA---AHAQQVKELQEQTGNLGRQREACMREAEELRTQLRLLEDTRDGLRR 1177
Cdd:TIGR02169  693 LQSELRRIENRLDELSQELSDASRKIGEIEKeieQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEE 772

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1178 ELLEAQRKVRDSQDSSEAHRQEasELRRSLSEGTKEREALRRSNEELRTAVKKAESERISLKLANEDKEQKLALLEEARM 1257
Cdd:TIGR02169  773 DLHKLEEALNDLEARLSHSRIP--EIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIK 850

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1258 SVAKEAGELRASLQEVERSRLEARRELQELRRQMKTLDSDNGRLGRELADLQSRL--ALGERTEKESRREVLGLRQKVLK 1335
Cdd:TIGR02169  851 SIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIeeLEAQIEKKRKRLSELKAKLEALE 930

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1336 GE-SSLEALKQELQGS----------QRKLQEQEAEFRARERGLLGSLEEARGAEKKLLDsarsLELRLEGVRAETSELG 1404
Cdd:TIGR02169  931 EElSEIEDPKGEDEEIpeeelsledvQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDE----LKEKRAKLEEERKAIL 1006


                   ..
gi 1958776745 1405 LR 1406
Cdd:TIGR02169 1007 ER 1008
PTZ00121 PTZ00121
MAEBL; Provisional
 954-1662 1.79e-12

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 73.25  E-value: 1.79e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  954 RQQVTATEEKAALD--KELMTQKLVQAERETQASLREQRAAHEEDLQRLQ--REKEAAWRELQAERAQLQGQLQQEREEL 1029
Cdd:PTZ00121  1088 RADEATEEAFGKAEeaKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEdaRKAEEARKAEDAKRVEIARKAEDARKAE 1167

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1030 LARMEAEKEELSEEIAALQQERDEGLLLAESEK--QQALSLKESEKTALSEKLMGTRHSLAAISLEMERQKRDAQSRQEQ 1107
Cdd:PTZ00121  1168 EARKAEDAKKAEAARKAEEVRKAEELRKAEDARkaEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEE 1247

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1108 DRNTVNALTSELRDLRAQLEEATAAHAQQVKELQEqtgnlgrqreacMREAEELRT--QLRLLEDTR--DGLRRELLEAq 1183
Cdd:PTZ00121  1248 ERNNEEIRKFEEARMAHFARRQAAIKAEEARKADE------------LKKAEEKKKadEAKKAEEKKkaDEAKKKAEEA- 1314

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1184 RKVRDSQDSSEAHRQEASELRRSLSEGTKEREALRRSNEELRTAVKKAESERISLKLANEDKEQKLALL----EEARMS- 1258
Cdd:PTZ00121  1315 KKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAkkkaEEKKKAd 1394

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1259 -VAKEAGELRASLQEVERSRlEARRELQELRRQMKTL-DSDNGRLGREladlQSRLALGERTEKESRREVLGLRQKVLKG 1336
Cdd:PTZ00121  1395 eAKKKAEEDKKKADELKKAA-AAKKKADEAKKKAEEKkKADEAKKKAE----EAKKADEAKKKAEEAKKAEEAKKKAEEA 1469

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1337 ESSLEALKQelqgSQRKLQEQEAEFRARERGllGSLEEARGAE--KKLLDSARSLELRL---EGVRAETSELGLRLSAAE 1411
Cdd:PTZ00121  1470 KKADEAKKK----AEEAKKADEAKKKAEEAK--KKADEAKKAAeaKKKADEAKKAEEAKkadEAKKAEEAKKADEAKKAE 1543

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1412 GRAQGLEV----ELARVEAQRRVAEAQlgglRSALRRGLGLGRVssspareapaggsgdglsspsplEYSPRSQPPSPGP 1487
Cdd:PTZ00121  1544 EKKKADELkkaeELKKAEEKKKAEEAK----KAEEDKNMALRKA-----------------------EEAKKAEEARIEE 1596

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1488 VASPAPPDLDPEAvrdalrdflQELRSAQRERDElrvqtstlSQQLAEMEAERDHAASRAKQLQKAVAESEEAwRSADRR 1567
Cdd:PTZ00121  1597 VMKLYEEEKKMKA---------EEAKKAEEAKIK--------AEELKKAEEEKKKVEQLKKKEAEEKKKAEEL-KKAEEE 1658

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1568 LSGAQAELALQEESVRRSRRECRATldqmavlERSLQATESELRASQEKVNKMKATEVKLESDKRRLKEVLDASESRSIK 1647
Cdd:PTZ00121  1659 NKIKAAEEAKKAEEDKKKAEEAKKA-------EEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIK 1731

                          730
                   ....*....|....*
gi 1958776745 1648 LELQRRALEGELQRS 1662
Cdd:PTZ00121  1732 AEEAKKEAEEDKKKA 1746
PTZ00121 PTZ00121
MAEBL; Provisional
 959-1725 4.67e-11

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 68.63  E-value: 4.67e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  959 ATEEKAALDKELMTQKLVQAERETQASLREQRAaheEDLQRLQREKEAAwrelQAERAQLQGQLQQEREELLARMEAEKE 1038
Cdd:PTZ00121  1092 ATEEAFGKAEEAKKTETGKAEEARKAEEAKKKA---EDARKAEEARKAE----DARKAEEARKAEDAKRVEIARKAEDAR 1164

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1039 ELSEEIAALQQERDEGLLLAEsEKQQALSLKESEKTalseklmgtRHSLAAISLEMERQKRDAQSRQEQDRNTVNALTSE 1118
Cdd:PTZ00121  1165 KAEEARKAEDAKKAEAARKAE-EVRKAEELRKAEDA---------RKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEE 1234

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1119 LRDLRAQLEEATAAHAQQVKELQEQTGNLGRQREACMREAEELRT--QLRLLEDTRDGLRRELLEAQRKVRDSQDSSEAH 1196
Cdd:PTZ00121  1235 AKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKadELKKAEEKKKADEAKKAEEKKKADEAKKKAEEA 1314

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1197 RQeASELRRSLSEGTKEREALRRSNEELRTA--VKKAESERISLKLANEDKEQKLAllEEARMSVAKEAGELRASLQEVE 1274
Cdd:PTZ00121  1315 KK-ADEAKKKAEEAKKKADAAKKKAEEAKKAaeAAKAEAEAAADEAEAAEEKAEAA--EKKKEEAKKKADAAKKKAEEKK 1391

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1275 RSRlEARRELQELRRQMKTLdsdngrlgreladlqsrlalgeRTEKESRREVLGLRQKVLKGESSLEALKQELQGSQRKL 1354
Cdd:PTZ00121  1392 KAD-EAKKKAEEDKKKADEL----------------------KKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADE 1448

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1355 QEQEAEFRARERGLLGSLEEARGAE---KKLLDSARSLELRLEGVRAETSELGLRLSAAEGRAQGlevELARVEAQRRVA 1431
Cdd:PTZ00121  1449 AKKKAEEAKKAEEAKKKAEEAKKADeakKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKAD---EAKKAEEAKKAD 1525

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1432 EAQlgglrsalrrglglgrvSSSPAREAPAggsgdglsspspleysprsqppspgpvASPAPPDLDPEAVRDAlrdflQE 1511
Cdd:PTZ00121  1526 EAK-----------------KAEEAKKADE---------------------------AKKAEEKKKADELKKA-----EE 1556

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1512 LRSAQRERDelrvqtstlSQQLAEMEAERDHAASRAKQLQKAVAESEEAWRSADRRLSGAQAELALQEESVRRSRRECRA 1591
Cdd:PTZ00121  1557 LKKAEEKKK---------AEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKK 1627

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1592 TLDQMAVLERSLQATESELRASQ-----EKVNKMKATEV--KLESDKRRLKEVLDASESRSIKLELQRRALEGELQRSRL 1664
Cdd:PTZ00121  1628 AEEEKKKVEQLKKKEAEEKKKAEelkkaEEENKIKAAEEakKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEEL 1707

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1958776745 1665 GLGDREAHAQALQDRVDSLQRQVADSEVKAGTLQltvERLSGALAKVEESEgtlRSKVQSL 1725
Cdd:PTZ00121  1708 KKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEE---DKKKAEEAKKDEEE---KKKIAHL 1762
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 569-1295 7.25e-11

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 67.84  E-value: 7.25e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  569 EEQLQRLRDQTATSVQaqeDAQReaqRLRSANEILSREKGNLSHSLQVAQQQAEDLRQELEKLQAAQEELRRQHTQLEDQ 648
Cdd:pfam15921   73 KEHIERVLEEYSHQVK---DLQR---RLNESNELHEKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQ 146

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  649 QEDTVQ--EGARARRE--LERSHRQLEQLE---VKRSGLTKE----LVEVREALSCAVLQRDVLQTEK-AEVAEALTKAe 716
Cdd:pfam15921  147 LQNTVHelEAAKCLKEdmLEDSNTQIEQLRkmmLSHEGVLQEirsiLVDFEEASGKKIYEHDSMSTMHfRSLGSAISKI- 225

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  717 agRAQLELSVTKLRAEEASLRDSLSKMsalnESLAQDKLEL------NRLIAQLEEEKAALLGRQQQAEHATSLAVEKQE 790
Cdd:pfam15921  226 --LRELDTEISYLKGRIFPVEDQLEAL----KSESQNKIELllqqhqDRIEQLISEHEVEITGLTEKASSARSQANSIQS 299

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  791 RLEQLR----------------LEQEVE--RQGLEGSLCVAEQAREALGQQILVLRSERSHLQEQVAQLSRQLNGRDQEL 852
Cdd:pfam15921  300 QLEIIQeqarnqnsmymrqlsdLESTVSqlRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQL 379

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  853 DQALRESQRQVEALERAAREKEAMAKERAGLAVQLAAAEREGRTLSEETIRLRLEKEALESSL-FDVQRQLAQLEARREQ 931
Cdd:pfam15921  380 QKLLADLHKREKELSLEKEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECqGQMERQMAAIQGKNES 459

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  932 LEADSqALLLAKETLTGELAGLRQQVTA------TEEKAALDKELMTQKLVQAERETQASLREQRAAHEEDLQRLQ--RE 1003
Cdd:pfam15921  460 LEKVS-SLTAQLESTKEMLRKVVEELTAkkmtleSSERTVSDLTASLQEKERAIEATNAEITKLRSRVDLKLQELQhlKN 538

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1004 KEAAWRELQAERAQLQGQLqQEREELLARMEAEKEELSEEIAalQQERDEGLLLAESEK------QQALSLKESeKTALS 1077
Cdd:pfam15921  539 EGDHLRNVQTECEALKLQM-AEKDKVIEILRQQIENMTQLVG--QHGRTAGAMQVEKAQlekeinDRRLELQEF-KILKD 614

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1078 EKLMGTRHSLAAIS-LEMERQK------------RDAQSRQEQDRNTVNALTSELRDLRAQLEEATAAHAQQVKELQEQT 1144
Cdd:pfam15921  615 KKDAKIRELEARVSdLELEKVKlvnagserlravKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTT 694

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1145 GNLGRQREACMREAEELRTQLRLLEDTRDGLRRELLEAQRKVRDSQDSSEAHRQEASELRRSLSEGTKEREALRRSNEEL 1224
Cdd:pfam15921  695 NKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKL 774

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1958776745 1225 RTAVKKAESERISLKLANEDKEQKLALLEE--ARMSVAKEagelRASLQEVERSRLEARRELQELRRQMK-TLD 1295
Cdd:pfam15921  775 SQELSTVATEKNKMAGELEVLRSQERRLKEkvANMEVALD----KASLQFAECQDIIQRQEQESVRLKLQhTLD 844
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 78-674 9.67e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 67.27  E-value: 9.67e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745   78 LLSLQEENQLLQQELSRVEDLLAQSRAERDELAIKYNAINERLEQAvrletgELEAQEPRGLVRQSVELRRQLQEEQASY 157
Cdd:COG1196    234 LRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEEL------ELELEEAQAEEYELLAELARLEQDIARL 307

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  158 RRKLQAYQEGQQRQAQLVQRLQAKILQYKKQCSEMEKQLLERSTELEQQRLRDTEHSQDLDRALLRLEEEQQRSASLAQv 237
Cdd:COG1196    308 EERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAE- 386

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  238 nDMLREQLDQANLANQTLSEDickvtsdwtRSCKELEQREATWRREEESFNAYfSSEHSRLLLLWRQVMGLRRMASEVKM 317
Cdd:COG1196    387 -ELLEALRAAAELAAQLEELE---------EAEEALLERLERLEEELEELEEA-LAELEEEEEEEEEALEEAAEEEAELE 455

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  318 GTERDLLQLGGELVRTSRAVQEVGLGLSASLQRAESRAEAALEKQKLLQAQLEEQLRAKLLREKDLAQLQVQSDLDKADL 397
Cdd:COG1196    456 EEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAA 535

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  398 SARVTELALSVEhLQNQNTEKDQVnrtLSDKLEALESLRLQEQTTLDTEDGEGLQQTLRDLAQAALSDTESGVQLSNSER 477
Cdd:COG1196    536 YEAALEAALAAA-LQNIVVEDDEV---AAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREA 611

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  478 TADTSDGSFRGLFGQRTPTPPRhsspgrgrsprrglspacsdsSTLTLIHSALHKRQLQVQDMRGRYEASQDLLGSVRKQ 557
Cdd:COG1196    612 DARYYVLGDTLLGRTLVAARLE---------------------AALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRREL 670

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  558 LSDSEGERRGLEEQLQRLRDQTATSVQAQEDAQREAQRLRSANEILSREKgnlsHSLQVAQQQAEDLRQELEKLQAAQEE 637
Cdd:COG1196    671 LAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEE----LEEEALEEQLEAEREELLEELLEEEE 746

                          570       580       590
                   ....*....|....*....|....*....|....*..
gi 1958776745  638 LRRQHTQLEDQQEDTVQEgarARRELERSHRQLEQLE 674
Cdd:COG1196    747 LLEEEALEELPEPPDLEE---LERELERLEREIEALG 780
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 959-1713 1.11e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 67.02  E-value: 1.11e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  959 ATEEKAALDKELMTQKLVQAERETQASLREQRAAHEEDLQRLQREKE--------AAWRELQAERAQLQGQLQQEREELl 1030
Cdd:TIGR02169  175 ALEELEEVEENIERLDLIIDEKRQQLERLRREREKAERYQALLKEKReyegyellKEKEALERQKEAIERQLASLEEEL- 253

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1031 ARMEAEKEELSEEIAALQQERDEglllaESEKQQALSLKES-EKTALSEKLMGTRHSLAAISLEMERQKRDAQSRQEQDR 1109
Cdd:TIGR02169  254 EKLTEEISELEKRLEEIEQLLEE-----LNKKIKDLGEEEQlRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLE 328

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1110 NTVNALTSELRDLRAQLEEATAAHAQ---QVKELQEQTGNLGRQREACMREAEELRTQLRLLEDTRDGLRRELLEAQRKV 1186
Cdd:TIGR02169  329 AEIDKLLAEIEELEREIEEERKRRDKlteEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKREL 408

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1187 RDSQDSSEAHRQEASELRRSLSEGTKEREALRRSNEELRTAVKKAESERISLKLANEDKEQKLALLEEARMSVAKEAGEL 1266
Cdd:TIGR02169  409 DRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKL 488

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1267 RASLQEVERSRLEARRELQELRRQMKTLDSDNGRLGRELADLQS---------RLALGER-------------------- 1317
Cdd:TIGR02169  489 QRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSvgeryataiEVAAGNRlnnvvveddavakeaiellk 568

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1318 TEKESRREVLGLRqKVLKGESSLEALKQE-LQGSQRKLQEQEAEFRA------RERGLLGSLEEARgaekKLLDSARSLE 1390
Cdd:TIGR02169  569 RRKAGRATFLPLN-KMRDERRDLSILSEDgVIGFAVDLVEFDPKYEPafkyvfGDTLVVEDIEAAR----RLMGKYRMVT 643

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1391 LRLEGVRAETSELG--LRLSAAEGRAQGLEVELARVEAQRRVAEAQLGGLRSALRRGLGLGRVSSSPAREApaggsgdgl 1468
Cdd:TIGR02169  644 LEGELFEKSGAMTGgsRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDA--------- 714

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1469 sSPSPLEYSPRSQPPspgpvaspappDLDPEAVRDALRDFLQELRSAQRERDELRVQTSTLSQQLAEMEA---------- 1538
Cdd:TIGR02169  715 -SRKIGEIEKEIEQL-----------EQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEdlhkleealn 782

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1539 --ERDHAASRAKQLQ-------KAVAESEEAWRSADRRLSGAQAELALQEESVRRSRRECRATLDQMAVLERSLQATESE 1609
Cdd:TIGR02169  783 dlEARLSHSRIPEIQaelskleEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGK 862

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1610 LRASQEKVNKMKATEVKLESDKRRLKEVLDASESRSIKLELQRRALEGELQRSRLGLGDREAHAQALQDRVDSLQRQVAD 1689
Cdd:TIGR02169  863 KEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGE 942

                          810       820       830
                   ....*....|....*....|....*....|
gi 1958776745 1690 ------SEVKAGTLQLTVERLSGALAKVEE 1713
Cdd:TIGR02169  943 deeipeEELSLEDVQAELQRVEEEIRALEP 972
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 530-1283 1.48e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 66.63  E-value: 1.48e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  530 LHKRQLQVQDMRGRYEASQDLLGSVRKQLSDSEGER--------RGLEEQLQRLRDQTATSVQAQEDAQREAQRLRSANE 601
Cdd:TIGR02169  253 LEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEqlrvkekiGELEAEIASLERSIAEKERELEDAEERLAKLEAEID 332

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  602 ILSREKGNLSHSLQVAQQQAEDLRQELEKLQAAQEELRRQHTQLEDQQEDTVQEGARARRELERSHRQLEQLEVKRSGLT 681
Cdd:TIGR02169  333 KLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQ 412

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  682 KELVEVREALSCAVLQRDVLQTEKAEVAEALT----KAEAGRAQLELSVTKLRAEEASLRDSLSKMSALNESLAQDKLEL 757
Cdd:TIGR02169  413 EELQRLSEELADLNAAIAGIEAKINELEEEKEdkalEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQREL 492

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  758 NRLIAQLEEEKAALLGRQQQ----------------------AEHATSLAVEKQERLEQLRLEQEV----------ERQG 805
Cdd:TIGR02169  493 AEAEAQARASEERVRGGRAVeevlkasiqgvhgtvaqlgsvgERYATAIEVAAGNRLNNVVVEDDAvakeaiellkRRKA 572

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  806 ----------------------LEGSLCVA---------------------------EQAREALGQQILVLrsershLQE 836
Cdd:TIGR02169  573 gratflplnkmrderrdlsilsEDGVIGFAvdlvefdpkyepafkyvfgdtlvvediEAARRLMGKYRMVT------LEG 646

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  837 QVAQLSRQLNGRDQELDQALRESQRQVEALERAAREKEAMAKERAGLAVQLAAAERegrtlseetirlrlEKEALESSLF 916
Cdd:TIGR02169  647 ELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIEN--------------RLDELSQELS 712

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  917 DVQRQLAQLEARREQLEADsqalllaKETLTGELAGLRQQVTATEEKAAldkelmtqklvqAERETQASLREQRAAHEED 996
Cdd:TIGR02169  713 DASRKIGEIEKEIEQLEQE-------EEKLKERLEELEEDLSSLEQEIE------------NVKSELKELEARIEELEED 773

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  997 LQRLQREKEAAWRELQAERAQLQGQLQQEREELLARMEAEKEELSEEIAALQQERDegllLAESEKQqalslkesektal 1076
Cdd:TIGR02169  774 LHKLEEALNDLEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKE----YLEKEIQ------------- 836

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1077 seklmgtrhslaaislEMERQKRDAQSRQEQDRNTVNALTSELRDLRAQLEEATAAhaqqVKELQEQTGNLGRQReacmr 1156
Cdd:TIGR02169  837 ----------------ELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAA----LRDLESRLGDLKKER----- 891

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1157 eaEELRTQLRLLEDTRDGLRRELLEAQRKVRDSQDSSEAHRQEASELRRSLSEGTKEREALrRSNEELRTAVKKAESERI 1236
Cdd:TIGR02169  892 --DELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEE-LSLEDVQAELQRVEEEIR 968

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1958776745 1237 SLKLAN-------EDKEQKLALLEEARMSVAKEAGELRASLQEVERSRLEARRE 1283
Cdd:TIGR02169  969 ALEPVNmlaiqeyEEVLKRLDELKEKRAKLEEERKAILERIEEYEKKKREVFME 1022
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
568-1033 2.20e-10

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 66.22  E-value: 2.20e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  568 LEEQLQRLRDQTATSVQAQEDAQREAQRLRSANEILSREKGNLSHSLQVAQQQAEDLRQELEKLQAAQEELRRQHTQLED 647
Cdd:PRK02224   256 LEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRV 335

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  648 QQEDTVQEGARARRELERSHRQLEQLEVKRSGLTKELVEVREALSCAVLQRDVLQTEKAEVAEALTKAEAGRAQLELSVT 727
Cdd:PRK02224   336 AAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLE 415

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  728 KLRAEEASLRDSLSKMSALNESLAQDKLELNRLiaqLEEEKAALLGRQ-QQAEHATSLA--VEKQERLEQLRLEQEVERQ 804
Cdd:PRK02224   416 ELREERDELREREAELEATLRTARERVEEAEAL---LEAGKCPECGQPvEGSPHVETIEedRERVEELEAELEDLEEEVE 492

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  805 GLEGSLCVAEQAREAlGQQILVLRSERSHLQEQVAQLSRQLNgRDQELDQALRESQRQVEALERAAREKEAMAKERAG-L 883
Cdd:PRK02224   493 EVEERLERAEDLVEA-EDRIERLEERREDLEELIAERRETIE-EKRERAEELRERAAELEAEAEEKREAAAEAEEEAEeA 570

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  884 AVQLAAAEREGRTLSEETIRLrlekEALESSLFDVQRQLAQLEARREQLEADSQALLLAKETLtGELAGLRQQVTATEEK 963
Cdd:PRK02224   571 REEVAELNSKLAELKERIESL----ERIRTLLAAIADAEDEIERLREKREALAELNDERRERL-AEKRERKRELEAEFDE 645

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  964 AAL-----DKELMTQKLVQAERETQA-----------------------SLREQRAAHEEDLQRLQREKEAAwRELQAER 1015
Cdd:PRK02224   646 ARIeeareDKERAEEYLEQVEEKLDElreerddlqaeigaveneleeleELRERREALENRVEALEALYDEA-EELESMY 724

                          490
                   ....*....|....*...
gi 1958776745 1016 AQLQGQLQQEREELLARM 1033
Cdd:PRK02224   725 GDLRAELRQRNVETLERM 742
PTZ00121 PTZ00121
MAEBL; Provisional
 831-1435 6.23e-10

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 64.78  E-value: 6.23e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  831 RSHLQEQVAQLsRQLNGRDQELDQALRESQRQVEALERAAREKEAMAKERAGLAVQLAAAErEGRTLSEETIRLRLEKEA 910
Cdd:PTZ00121  1059 KAEAKAHVGQD-EGLKPSYKDFDFDAKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAE-EAKKKAEDARKAEEARKA 1136

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  911 LESSLFDVQRQLAqlEARREQLEADSQALLLAKETLTGELAGLRQQVTATEE--KAALDKELMTQKLVQAERETQASLRE 988
Cdd:PTZ00121  1137 EDARKAEEARKAE--DAKRVEIARKAEDARKAEEARKAEDAKKAEAARKAEEvrKAEELRKAEDARKAEAARKAEEERKA 1214

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  989 QRAAHEEDLQRLQ---REKEAAWRELQAERAQLQGQLQQEREELLARMEAEKEELSEEIAALQQERDEglLLAESEKQQA 1065
Cdd:PTZ00121  1215 EEARKAEDAKKAEavkKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADE--LKKAEEKKKA 1292

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1066 LSLKESEKTALSEKLMGTRHS------LAAISLEMERQKRDAQSRQEQDRNTVNALTSELRDLRAQLEEA--TAAHAQQV 1137
Cdd:PTZ00121  1293 DEAKKAEEKKKADEAKKKAEEakkadeAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAeeKAEAAEKK 1372

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1138 KELQEQTGNLGRQREACMREAEELRTQLRLLEDTRDGLRREllEAQRKVRDSQDSSEAHRQEASELRRSLSEGTKEREAL 1217
Cdd:PTZ00121  1373 KEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKA--AAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAK 1450

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1218 RRSNEELRT--AVKKAESERISLKLANEDKEQKLAllEEARM---SVAKEAGELRASLQEVERS---------------- 1276
Cdd:PTZ00121  1451 KKAEEAKKAeeAKKKAEEAKKADEAKKKAEEAKKA--DEAKKkaeEAKKKADEAKKAAEAKKKAdeakkaeeakkadeak 1528

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1277 RLEARRELQELRRQMKTLDSDNGRLGRELADLQSRLALGERTEKESRREVLGLRQKVLK-GESSLEALKQELQGSQRKLQ 1355
Cdd:PTZ00121  1529 KAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKkAEEARIEEVMKLYEEEKKMK 1608

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1356 EQEAEFRARERGLLGSLEEARGAEKKLLDSARSLE---LRLEGVRAETSELGLR---LSAAEGRAQGLEVELARVEAQRR 1429
Cdd:PTZ00121  1609 AEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAeekKKAEELKKAEEENKIKaaeEAKKAEEDKKKAEEAKKAEEDEK 1688


                   ....*.
gi 1958776745 1430 VAEAQL 1435
Cdd:PTZ00121  1689 KAAEAL 1694
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 581-1230 7.69e-10

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 64.47  E-value: 7.69e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  581 TSVQAQEDAQREAQRLRSANEILSREKGNLSHSLQVAQQQAEDLRQEL----EKLQAAQEELRRQHTQLEDQQEDTVQEG 656
Cdd:pfam12128  263 LHFGYKSDETLIASRQEERQETSAELNQLLRTLDDQWKEKRDELNGELsaadAAVAKDRSELEALEDQHGAFLDADIETA 342

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  657 ARARRELERSHRQLEQLEVKRSGLTKELVEVREALSCAVLQRDvlqtekAEVAEALTKAEAGRAQLELSVTKLRAEEASL 736
Cdd:pfam12128  343 AADQEQLPSWQSELENLEERLKALTGKHQDVTAKYNRRRSKIK------EQNNRDIAGIKDKLAKIREARDRQLAVAEDD 416

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  737 RDSLSkmSALNESLAQDKLELN----RLIAQLEEEKAALLGRQQQAEHATSLAVeKQERLEQLRLEQEVERQGlegslcv 812
Cdd:pfam12128  417 LQALE--SELREQLEAGKLEFNeeeyRLKSRLGELKLRLNQATATPELLLQLEN-FDERIERAREEQEAANAE------- 486

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  813 aeqaREALGQQILVLRSERSHLQEQVAQLSRQLNGRDQELDQALRESQRQVEALERAAREKEAMAKERAGlavQLAAAER 892
Cdd:pfam12128  487 ----VERLQSELRQARKRRDQASEALRQASRRLEERQSALDELELQLFPQAGTLLHFLRKEAPDWEQSIG---KVISPEL 559

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  893 EGRT--------------LSEETIRLRLEKEALESSLFDVQrqlaQLEARREQLEADSQALLLAKETLTGELAGLRQQVt 958
Cdd:pfam12128  560 LHRTdldpevwdgsvggeLNLYGVKLDLKRIDVPEWAASEE----ELRERLDKAEEALQSAREKQAAAEEQLVQANGEL- 634

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  959 ateEKAALDKELMTQKLVQAeretqaslreqraahEEDLQRLQREKEAAWRELQAERAQLQGQLQQEREELLArmeaEKE 1038
Cdd:pfam12128  635 ---EKASREETFARTALKNA---------------RLDLRRLFDEKQSEKDKKNKALAERKDSANERLNSLEA----QLK 692

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1039 ELSEEIAALQQERDEGLLLAESEKQQALSLKESEKTA----LSEKLMGTRHSLAAISLEMERQKRDAQSRQEQDRNTVNA 1114
Cdd:pfam12128  693 QLDKKHQAWLEEQKEQKREARTEKQAYWQVVEGALDAqlalLKAAIAARRSGAKAELKALETWYKRDLASLGVDPDVIAK 772

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1115 LTSELRDLRAQLE-------EATAAHAQQVKELQEQTGNLGRQREACMREAEELRTQL-RLLEDTRdgLRRELLEAQRKV 1186
Cdd:pfam12128  773 LKREIRTLERKIEriavrrqEVLRYFDWYQETWLQRRPRLATQLSNIERAISELQQQLaRLIADTK--LRRAKLEMERKA 850

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1958776745 1187 RDSQ--DSSEAHRQEASELRR---------------SLSEGTKEREALRRSNEELRTAVKK 1230
Cdd:pfam12128  851 SEKQqvRLSENLRGLRCEMSKlatlkedanseqaqgSIGERLAQLEDLKLKRDYLSESVKK 911
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
854-1357 7.69e-10

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 64.55  E-value: 7.69e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  854 QALRESQRQVEALERAAREKEAMAKERAGLAVQ--------LAAAEREGRTLSEETIRLRLEKEALESSLFDVQRQLAQL 925
Cdd:COG4913    242 EALEDAREQIELLEPIRELAERYAAARERLAELeylraalrLWFAQRRLELLEAELEELRAELARLEAELERLEARLDAL 321

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  926 EARREQLEAD-SQALLLAKETLTGELAGLRQQVTATEEKAALDKELmTQKLVQAERETQASLREQRAAHEEDLQRLQREK 1004
Cdd:COG4913    322 REELDELEAQiRGNGGDRLEQLEREIERLERELEERERRRARLEAL-LAALGLPLPASAEEFAALRAEAAALLEALEEEL 400

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1005 EAAwRELQAERAQLQGQLQQEREELLARmeaekeelseeIAALQQER---DEGLLLAESEKQQALSLKESE--------- 1072
Cdd:COG4913    401 EAL-EEALAEAEAALRDLRRELRELEAE-----------IASLERRKsniPARLLALRDALAEALGLDEAElpfvgelie 468

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1073 --------KTALsEKLMGTRhslaAISLEMERQKRDAQSR---QEQDRNTVN---ALTSELRDLRAQLEEATAAHAQQVK 1138
Cdd:COG4913    469 vrpeeerwRGAI-ERVLGGF----ALTLLVPPEHYAAALRwvnRLHLRGRLVyerVRTGLPDPERPRLDPDSLAGKLDFK 543

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1139 E------LQEQtgnLGRQRE-ACMREAEELRTQLRLLedTRDGLRRELLEAQRK------------VRDSQDSSEAHRQE 1199
Cdd:COG4913    544 PhpfrawLEAE---LGRRFDyVCVDSPEELRRHPRAI--TRAGQVKGNGTRHEKddrrrirsryvlGFDNRAKLAALEAE 618

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1200 ASELRRSLSEGTKEREALRRSNEELRT------AVKKAESERISLKLANE---DKEQKLALLEEARMSVAkeagELRASL 1270
Cdd:COG4913    619 LAELEEELAEAEERLEALEAELDALQErrealqRLAEYSWDEIDVASAEReiaELEAELERLDASSDDLA----ALEEQL 694

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1271 QEVERSRLEARRELQELRRQMKTLDSDNGRLGRELADLQSRLALGERTEKESRREVLGLRQKVLKGESSLEALKQELQGS 1350
Cdd:COG4913    695 EELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVERELRENLEER 774


                   ....*..
gi 1958776745 1351 QRKLQEQ 1357
Cdd:COG4913    775 IDALRAR 781
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
533-1033 1.17e-09

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 63.78  E-value: 1.17e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  533 RQLQVQDMRGRYEASQDLLGSVRKQLSDSEGERRGLEEQLQRLRDQTATSVQAQ-EDAQREAQRLRSANEILSREKGNLS 611
Cdd:COG4913    286 AQRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGGDRlEQLEREIERLERELEERERRRARLE 365

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  612 HSLQVAQQQAEDLRQELEKLQAAQEELRRQHTQLEDQQEDTVQEGARARRELERSHRQLEQ----LEVKRSGLTKELVEV 687
Cdd:COG4913    366 ALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAeiasLERRKSNIPARLLAL 445

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  688 REAL--SCAVLQRDV--------LQTEKAEVAEALTKAEAGRA--------QLELSVTKLRAEEASLRDSLSKMSALNES 749
Cdd:COG4913    446 RDALaeALGLDEAELpfvgelieVRPEEERWRGAIERVLGGFAltllvppeHYAAALRWVNRLHLRGRLVYERVRTGLPD 525

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  750 LAQDKLELNRLIAQLEEEKAALLGRQQQaEHATSLAVEKQERLEQLRLEQE-VERQGL-EGSLCVAEQAREALGQQILVL 827
Cdd:COG4913    526 PERPRLDPDSLAGKLDFKPHPFRAWLEA-ELGRRFDYVCVDSPEELRRHPRaITRAGQvKGNGTRHEKDDRRRIRSRYVL 604

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  828 ----RSERSHLQEQVAQLSRQLngrdQELDQALRESQRQVEALERAAREKEAMAkERAGLAVQLAAAEREGRtlseetiR 903
Cdd:COG4913    605 gfdnRAKLAALEAELAELEEEL----AEAEERLEALEAELDALQERREALQRLA-EYSWDEIDVASAEREIA-------E 672

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  904 LRLEKEALESSLFDvqrqLAQLEARREQLEADSQALLLAKETLTGELAGLRQQVTATEEKAALDKELMTQKLVQAERETQ 983
Cdd:COG4913    673 LEAELERLDASSDD----LAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELR 748

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|
gi 1958776745  984 ASLREQRAAHEEDLQRlqrekEAAWRELQAERAQLQGQLQQEREELLARM 1033
Cdd:COG4913    749 ALLEERFAAALGDAVE-----RELRENLEERIDALRARLNRAEEELERAM 793
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1048-1883 1.92e-09

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 63.07  E-value: 1.92e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1048 QQERDEGLLLAESEKQQALSLKESEKTAL-----SEKLMGTRHSLAAISLEMERQKRDAQSRQEQdRNTVNALTSELRDL 1122
Cdd:pfam02463  182 TENLAELIIDLEELKLQELKLKEQAKKALeyyqlKEKLELEEEYLLYLDYLKLNEERIDLLQELL-RDEQEEIESSKQEI 260

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1123 RAQLEEATAAHAQQVKELQEQtGNLGRQREACMREAEELRTQLRLLEDTRDGLRRELLEAQRKVRDSQDSSEAHRQEASE 1202
Cdd:pfam02463  261 EKEEEKLAQVLKENKEEEKEK-KLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEE 339

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1203 LRRSLSEGTKEREALRRSNEELRTAVKKAESERislklanEDKEQKLALLEEARMSVAKEAGELRASLQEVERSRLEARR 1282
Cdd:pfam02463  340 LEKELKELEIKREAEEEEEEELEKLQEKLEQLE-------EELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLE 412

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1283 ELQELRRQMKTLDSDNGRLGRELADLQSRLALGERTEKESRREVLGLRQKVLKGESSLEALKQELQGSQRKLQEQEAEFR 1362
Cdd:pfam02463  413 LARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSR 492

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1363 ARERGLLGSLEEARGAEKKLLDSARSLELRLEGVRAETSELGLRLSAAEGRAQGLEVELARVEAQRRVAEAQLGGLRSAL 1442
Cdd:pfam02463  493 QKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTE 572

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1443 RRGLGLGRVSSSPAREAPAGGSGDGLSSPSPLEYSPRSQPPSPGPVASPAPPDLDPEAVRDALRDFLQELRSAQRERDEL 1522
Cdd:pfam02463  573 LPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGV 652

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1523 RVQTSTLSQQLAEMEAERDHAASRAKQLQKAVAESEEAWRSADRRLSGAQAELALQEESVRRSRRECRATLDQMAVLERS 1602
Cdd:pfam02463  653 SLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQD 732

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1603 LQATESELrasqekvNKMKATEVKLESDKRRLKEVLDASESRSIKLELQRRALEGELQRSRLGLGDREAHAQALQDRVDS 1682
Cdd:pfam02463  733 KINEELKL-------LKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRA 805

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1683 LQRQVADSEVKAGTLQLTVERLSGALAKVEESEGTLRSKVQSLTDALAQSSASLTSSQDKNLYLQKALSTCEHDRQVLQE 1762
Cdd:pfam02463  806 LEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLK 885

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1763 RLDAARQALSEARRQSSSLGEQVQTLRGELANLELQRGDAEGQLQQLQQVLRQRQEGEAVAlrSVQKLQEERRLLQERLG 1842
Cdd:pfam02463  886 DELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEAD--EKEKEENNKEEEEERNK 963

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|.
gi 1958776745 1843 SLQRALAQLEAEKRELERSALQLDKDRVALRKTLDKVEREK 1883
Cdd:pfam02463  964 RLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEK 1004
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1070-1432 2.15e-09

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 62.75  E-value: 2.15e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1070 ESEKTALSEKLMGTRHSLAAISLEMER---QKRDAQ----------SRQEQDRNTVNALTSELRDLRAQLEEAT---AAH 1133
Cdd:PRK02224   198 EKEEKDLHERLNGLESELAELDEEIERyeeQREQARetrdeadevlEEHEERREELETLEAEIEDLRETIAETErerEEL 277

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1134 AQQVKELQEQTGNLGRQREACMREAEELRTQLRLLEDTRDGLRRELLEAQRKVRDSQDSSEAHRQEASELRRSLSEGTKE 1213
Cdd:PRK02224   278 AEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEER 357

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1214 REALRRSNEELRTAVKKAESERISLKLANEDKEQKLALLEEARMSVAKEAGELRASLQEVERSRLEARRELQELRRQMKT 1293
Cdd:PRK02224   358 AEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRT 437

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1294 LDsDNGRLGRELADLQSRLALGERTEKESRREVLG-LRQKVLKGESSLEALKQELQGSQRKLQEQEAEFRARERglLGSL 1372
Cdd:PRK02224   438 AR-ERVEEAEALLEAGKCPECGQPVEGSPHVETIEeDRERVEELEAELEDLEEEVEEVEERLERAEDLVEAEDR--IERL 514

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1958776745 1373 EEARGAEKKLLDSARSL----ELRLEGVRAETSElgLRLSAAEGRAQGLEVELARVEAQRRVAE 1432
Cdd:PRK02224   515 EERREDLEELIAERRETieekRERAEELRERAAE--LEAEAEEKREAAAEAEEEAEEAREEVAE 576
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 866-1656 2.36e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 62.78  E-value: 2.36e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  866 LERAAREKEAMAKERAglaVQLAAAEREGRTLSEETIRLRLEKEALESSLFDVQRQLAQLEARREQLEADSQALLLAKET 945
Cdd:TIGR02169  200 LERLRREREKAERYQA---LLKEKREYEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEE 276

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  946 LTGELAGLrqqvtATEEKAALDKEL--MTQKLVQAERETQASLREQraaheEDLQRLQREKEAAWRELQAERAQLQGQLQ 1023
Cdd:TIGR02169  277 LNKKIKDL-----GEEEQLRVKEKIgeLEAEIASLERSIAEKEREL-----EDAEERLAKLEAEIDKLLAEIEELEREIE 346

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1024 QEREELLARMEAekeelseeIAALQQERDEGLLLAESEKQQALSLKEsEKTALSEKLMGTRHSLAAISLEMERQKRDAQS 1103
Cdd:TIGR02169  347 EERKRRDKLTEE--------YAELKEELEDLRAELEEVDKEFAETRD-ELKDYREKLEKLKREINELKRELDRLQEELQR 417

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1104 RQEQDRNTVNALTSeLRDLRAQLEEATAAHAQQVKELQEQTGNLGRQREACMREAEELRTQLRLLEDTRDGLRRELLEAQ 1183
Cdd:TIGR02169  418 LSEELADLNAAIAG-IEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAE 496

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1184 RKVRDSQDSSEAHRQEASELRRSLSEGTKEREALRRSNEELRTAVKKAESERI-------------SLKLANEDKEQKLA 1250
Cdd:TIGR02169  497 AQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEVAAGNRLnnvvveddavakeAIELLKRRKAGRAT 576

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1251 LLEEARM-------SVAKEAGELRASLQEVE-------------------RSRLEARRELQELRrqMKTLDSD------- 1297
Cdd:TIGR02169  577 FLPLNKMrderrdlSILSEDGVIGFAVDLVEfdpkyepafkyvfgdtlvvEDIEAARRLMGKYR--MVTLEGElfeksga 654

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1298 --------NGRLGRELADLQSRLALGERtEKESRREVLGLRQKVLKGESSLEALKQELQGSQRKLQEQEAEFRArergLL 1369
Cdd:TIGR02169  655 mtggsrapRGGILFSRSEPAELQRLRER-LEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQ----LE 729

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1370 GSLEEARGAEKKLLDSARSLELRLEGVRAETSELGLRLSAAEGRAQGLEVELARVEAqrRVAEAQLGGLRSALRRGLGLG 1449
Cdd:TIGR02169  730 QEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEA--RLSHSRIPEIQAELSKLEEEV 807

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1450 RVSSSPAREAPAggsgdGLSSPSPLEYSPRSQppSPGPVASPAPPDLDPEAVRDALRDFLQELRSAQRERDELRVQTSTL 1529
Cdd:TIGR02169  808 SRIEARLREIEQ-----KLNRLTLEKEYLEKE--IQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDL 880

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1530 SQQLAEMEAERDHAASRAKQLQKAVAESEEAWRSADRRLSGAQAELALQEESVRRSRRECRATLDQMAVlERSLQATESE 1609
Cdd:TIGR02169  881 ESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEE-ELSLEDVQAE 959

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|....*..
gi 1958776745 1610 LRASQEKVNKMKATEVKLESDKRRLKEVLDASESRSIKLELQRRALE 1656
Cdd:TIGR02169  960 LQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAIL 1006
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1159-1954 2.97e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 62.39  E-value: 2.97e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1159 EELRTQLRLLEDTRDGLRReLLEAQRKVRDSQDSSEAHRQEAseLRRSLSEGTKEREALRRSNEELRTAVKK--AESERI 1236
Cdd:TIGR02169  194 DEKRQQLERLRREREKAER-YQALLKEKREYEGYELLKEKEA--LERQKEAIERQLASLEEELEKLTEEISEleKRLEEI 270

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1237 SLKLANEDKEQKlALLEEARMSVAKEAGELRASLQEVERSRLEARRELQELRRQMKTLDSDNGRLGRELADLQSRLalge 1316
Cdd:TIGR02169  271 EQLLEELNKKIK-DLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREI---- 345

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1317 rTEKESRREVLglrqkvlkgESSLEALKQELQGSQRKLQEQEAEFRArergllgsleeargaekkLLDSARSLELRLEGV 1396
Cdd:TIGR02169  346 -EEERKRRDKL---------TEEYAELKEELEDLRAELEEVDKEFAE------------------TRDELKDYREKLEKL 397

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1397 RAETSELGLRLSAAEGRAQGLEVELARVEAQRRVAEAQLGGLRSALRRGLGLGRVSSSPAREAPAggsgdglsspspley 1476
Cdd:TIGR02169  398 KREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAA--------------- 462

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1477 sprsqppspgpvaspappdlDPEAVRDALRDFLQELRSAQRERdelrvqtSTLSQQLAEMEAERDhAASRAKQLQKAVAE 1556
Cdd:TIGR02169  463 --------------------DLSKYEQELYDLKEEYDRVEKEL-------SKLQRELAEAEAQAR-ASEERVRGGRAVEE 514

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1557 SEEAWRSAD----RRLSGAQAELALQEESVRRSRREcRATLDQMAVLERSLQATESEL--RASQEKVNKMKATevklESD 1630
Cdd:TIGR02169  515 VLKASIQGVhgtvAQLGSVGERYATAIEVAAGNRLN-NVVVEDDAVAKEAIELLKRRKagRATFLPLNKMRDE----RRD 589

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1631 KRRLKE------------------------------VLDASESRSIKLELQRRALEGEL-----------QRSRLGLGDR 1669
Cdd:TIGR02169  590 LSILSEdgvigfavdlvefdpkyepafkyvfgdtlvVEDIEAARRLMGKYRMVTLEGELfeksgamtggsRAPRGGILFS 669

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1670 ---EAHAQALQDRVDSLQRQVADSEVKAGTLQLTVERLSGALAKVEESEGTLRSKVQSLTDALAQSSASLTSSQDKNLYL 1746
Cdd:TIGR02169  670 rsePAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSL 749

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1747 QKALSTCEHDRQVLQERLDAARQALSEARRQSSSL-----GEQVQTLRGELANLELQRGDAEGQLQQLQQVLRQRQEGEA 1821
Cdd:TIGR02169  750 EQEIENVKSELKELEARIEELEEDLHKLEEALNDLearlsHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKE 829

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1822 VALRSVQKLQEERRLLQERLGSLQRALAQLEAEKRELERSALQLDKDRVALRKTLDKVEREKLRSHEDTLRLNAERGRLD 1901
Cdd:TIGR02169  830 YLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELE 909

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1958776745 1902 RTLTGAELDLAEAQQQIQHLEAQVVEVLERNHSPVQVEADEQHLE-LQQEVERL 1954
Cdd:TIGR02169  910 AQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEdVQAELQRV 963
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1499-1975 3.83e-09

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 62.24  E-value: 3.83e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1499 EAVRDALRDFLqelrsAQRERDELRVQTSTLSQQLAEMEAERDHAASRAKQLQKAVAESEEAWRSAD-RRLSGAQAELAL 1577
Cdd:COG4913    275 EYLRAALRLWF-----AQRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGgDRLEQLEREIER 349

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1578 QEESVRRSRRECRATLDQMAVLERSLQATESELRASQEKVNKMKATevkLESDKRRLKEVLDASESRSIKLELQRRALEG 1657
Cdd:COG4913    350 LERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEA---LEEELEALEEALAEAEAALRDLRRELRELEA 426

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1658 ELQRSRLGLGDREAHAQALQDRvdsLQRQVADSEVKA------------------------GTLQLTV----ERLSGALA 1709
Cdd:COG4913    427 EIASLERRKSNIPARLLALRDA---LAEALGLDEAELpfvgelievrpeeerwrgaiervlGGFALTLlvppEHYAAALR 503

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1710 KVEESEGTLR---SKVQSLTDALAQSSAsltssqDKNLYLQKaLSTCEHD-----RQVLQERLDAAR----QALSEARR- 1776
Cdd:COG4913    504 WVNRLHLRGRlvyERVRTGLPDPERPRL------DPDSLAGK-LDFKPHPfrawlEAELGRRFDYVCvdspEELRRHPRa 576

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1777 --------QSSSLGE-------------------QVQTLRGELANLELQRGDAEGQLQQLQQVLRQRQEgEAVALRSVQK 1829
Cdd:COG4913    577 itragqvkGNGTRHEkddrrrirsryvlgfdnraKLAALEAELAELEEELAEAEERLEALEAELDALQE-RREALQRLAE 655

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1830 LQEErrllQERLGSLQRALAQLEAEKRELERSALQLDkdrvALRKTLDKVEREKLRSHEDTLRLNAERGRLDRTLTGAEL 1909
Cdd:COG4913    656 YSWD----EIDVASAEREIAELEAELERLDASSDDLA----ALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEE 727

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1958776745 1910 DLAEAQQQIQHLEAQVVEVLERNHSPVQVEADEQHLE------LQQEVERLRSAQVRTERTLEARERAHRQR 1975
Cdd:COG4913    728 ELDELQDRLEAAEDLARLELRALLEERFAAALGDAVErelrenLEERIDALRARLNRAEEELERAMRAFNRE 799
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 730-1416 5.13e-09

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 61.78  E-value: 5.13e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  730 RAEEASLRDSLSKMSALNESLAQDKLELNRLIAQLEEEKAALLGRQQQAEHATSLAVEKQERLEQLRLEQeverqglegs 809
Cdd:pfam12128  272 TLIASRQEERQETSAELNQLLRTLDDQWKEKRDELNGELSAADAAVAKDRSELEALEDQHGAFLDADIET---------- 341

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  810 lcvaeqarealgqqilvlrseRSHLQEQVAQLSRQLNGRDQELDqALRESQRQVEAL--ERAAREKEAMAKERAGLAVQL 887
Cdd:pfam12128  342 ---------------------AAADQEQLPSWQSELENLEERLK-ALTGKHQDVTAKynRRRSKIKEQNNRDIAGIKDKL 399

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  888 AAaEREGRTLSEETIRLRLEkeALESSLFDvQRQLAQLEARREQLEADSQAlllaketltGELAGLRQQVTATEEKaaLD 967
Cdd:pfam12128  400 AK-IREARDRQLAVAEDDLQ--ALESELRE-QLEAGKLEFNEEEYRLKSRL---------GELKLRLNQATATPEL--LL 464

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  968 KELMTQKLVQAERETQASLREQRAAHEEDLQRLQREKEAAWRELQAERAQLQgQLQQEREELlarMEAEKEELSEEIAAL 1047
Cdd:pfam12128  465 QLENFDERIERAREEQEAANAEVERLQSELRQARKRRDQASEALRQASRRLE-ERQSALDEL---ELQLFPQAGTLLHFL 540

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1048 QQERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLAAISLEMERQkrdaqsrqeqDRNTVNALTSELRDLRAQLE 1127
Cdd:pfam12128  541 RKEAPDWEQSIGKVISPELLHRTDLDPEVWDGSVGGELNLYGVKLDLKRI----------DVPEWAASEEELRERLDKAE 610

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1128 EATAAHAQQVKELQEQTGNLGRQREACMREAEELRTQlrlLEDTRDGLRRELLEAQRKVRDSQDSSEAHRQEASELRRSL 1207
Cdd:pfam12128  611 EALQSAREKQAAAEEQLVQANGELEKASREETFARTA---LKNARLDLRRLFDEKQSEKDKKNKALAERKDSANERLNSL 687

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1208 SegtKEREALRRSNEELRTAVKKAESErislklANEDKEQKLALLEEARMSVAKEAGELRASLQEVERSRLEARRElqEL 1287
Cdd:pfam12128  688 E---AQLKQLDKKHQAWLEEQKEQKRE------ARTEKQAYWQVVEGALDAQLALLKAAIAARRSGAKAELKALET--WY 756

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1288 RRQMKTLDSDN---GRLGRELADLQSRLALGERTEKESRREVLGLRQKVLKGESSLEALKQELQGSQRKLQEQEAEFRAR 1364
Cdd:pfam12128  757 KRDLASLGVDPdviAKLKREIRTLERKIERIAVRRQEVLRYFDWYQETWLQRRPRLATQLSNIERAISELQQQLARLIAD 836

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1958776745 1365 ERGLLGSLEEARGAEKKLLDSARSLelrLEGVRAETSELG-LRLSAAEGRAQG 1416
Cdd:pfam12128  837 TKLRRAKLEMERKASEKQQVRLSEN---LRGLRCEMSKLAtLKEDANSEQAQG 886
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
815-1313 5.41e-09

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 61.47  E-value: 5.41e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  815 QAREALGQQILVLRSERSHLQEQVAQLSRQLNgrDQELDQALRESQRQVEALERAAREKEAMAKERAGLAVQLAAAEREg 894
Cdd:COG4913    262 ERYAAARERLAELEYLRAALRLWFAQRRLELL--EAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGGD- 338

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  895 rtlseetirlrlEKEALESSLFDVQRQLAQLEARREQLEADSQALLLAKETLTGELAGLRQQVTATEEKAALDKELMTQK 974
Cdd:COG4913    339 ------------RLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEA 406

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  975 LVQAERETQAsLREQRAAHEEDLQRLQREKEAAWRELQAERAQLQGQLQQEREEL--LA--------------------- 1031
Cdd:COG4913    407 LAEAEAALRD-LRRELRELEAEIASLERRKSNIPARLLALRDALAEALGLDEAELpfVGelievrpeeerwrgaiervlg 485

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1032 ----RMEAEKEELSEEIAALQQERDEGLL--LAESEKQQALSLKESEKTALSEKLMGTRHSLAAiSLEMERQKRDA---- 1101
Cdd:COG4913    486 gfalTLLVPPEHYAAALRWVNRLHLRGRLvyERVRTGLPDPERPRLDPDSLAGKLDFKPHPFRA-WLEAELGRRFDyvcv 564

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1102 ----QSRQEQDRNTVNALTSELRDLRA-QLEEATAAH-------AQQVKELQEQTGNLGRQREACMREAEELRTQLRLLE 1169
Cdd:COG4913    565 dspeELRRHPRAITRAGQVKGNGTRHEkDDRRRIRSRyvlgfdnRAKLAALEAELAELEEELAEAEERLEALEAELDALQ 644

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1170 DTRDGLRRelLEAQRKVRDSQDSSEAHRQEASELRRSLSEGTKEREALRRSNEELRTAVKKAESERISLKLANEDKEQKL 1249
Cdd:COG4913    645 ERREALQR--LAEYSWDEIDVASAEREIAELEAELERLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKEL 722

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1958776745 1250 ALLEEARMSVAKEAGELRASLQEVERSRLEARRELQELRRQMKTLDSdngRLGRELADLQSRLA 1313
Cdd:COG4913    723 EQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVERELRE---NLEERIDALRARLN 783
mukB PRK04863
chromosome partition protein MukB;
562-1001 5.45e-09

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 61.90  E-value: 5.45e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  562 EGERRGLEEQLQRLRDQTATSVQAQEDAQREAQRLRSANEILSREKGNLSHSLQVA---QQQAEDLRQELEKLQAAQEEL 638
Cdd:PRK04863   278 ANERRVHLEEALELRRELYTSRRQLAAEQYRLVEMARELAELNEAESDLEQDYQAAsdhLNLVQTALRQQEKIERYQADL 357

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  639 RRQHTQLEDQQEdtVQEGARARRELERSHRQLEQLEVKRsgLTKELVEVREALscavlqrDVLQTEKAEVAEALTKAEAG 718
Cdd:PRK04863   358 EELEERLEEQNE--VVEEADEQQEENEARAEAAEEEVDE--LKSQLADYQQAL-------DVQQTRAIQYQQAVQALERA 426

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  719 RAQLELSvtklraeeaslrdslskmsalneSLAQDKLE--LNRLIAQLEEEKAALLgrqqQAEHATSLAVEKQERLEQ-- 794
Cdd:PRK04863   427 KQLCGLP-----------------------DLTADNAEdwLEEFQAKEQEATEELL----SLEQKLSVAQAAHSQFEQay 479

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  795 ---LRLEQEVERQGlegslcVAEQAREALGQqilvLRSERsHLQEQVAQLSRQLNgrdqELDQALRESQRQVEALERAAR 871
Cdd:PRK04863   480 qlvRKIAGEVSRSE------AWDVARELLRR----LREQR-HLAEQLQQLRMRLS----ELEQRLRQQQRAERLLAEFCK 544

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  872 EKEAMAKERAGLAVQLAAAEREGRTLSEetirlrlEKEALESSLFDVQRQLAQLEARREQLEADSQALLLAKETltgeLA 951
Cdd:PRK04863   545 RLGKNLDDEDELEQLQEELEARLESLSE-------SVSEARERRMALRQQLEQLQARIQRLAARAPAWLAAQDA----LA 613

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1958776745  952 GLRQQVTATEEKAALDKELMTQKLVQaERETQAS---LREQRAAHEEDLQRLQ 1001
Cdd:PRK04863   614 RLREQSGEEFEDSQDVTEYMQQLLER-ERELTVErdeLAARKQALDEEIERLS 665
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 622-1366 5.84e-09

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 61.53  E-value: 5.84e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  622 EDLRQELEKLQAAQEELRRQHTQLEDQQEDTVQEGARARRELERSHRQLEQLEVKRSGLTKELVEVREALSCAVLQRDVL 701
Cdd:pfam02463  169 RKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRD 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  702 QTEKAEVAEALTKAEAGRAQLELSVTKLRAEEASLRDSLSKMSALN-ESLAQDKLELNRLIAQLEEEKAALLGRQQQAEH 780
Cdd:pfam02463  249 EQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEeEELKSELLKLERRKVDDEEKLKESEKEKKKAEK 328

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  781 ATSLAVEKQERLEQLRLEQEVERQGLEGSlcvAEQAREALGQQILVLRSERSHLQEQVAQLSRQLNGRDQELDQALRESQ 860
Cdd:pfam02463  329 ELKKEKEEIEELEKELKELEIKREAEEEE---EEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEK 405

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  861 RQVEALERAAREKEAMAKERAGLAVQLAAAEREGRTLSEETIRLRLEKEALESSLFDVQRQLAQLEARREQLEADSQALL 940
Cdd:pfam02463  406 EAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQ 485

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  941 LAKETLTGELAGLRQQVTATEEKAALDKELMTQKLVQaeRETQASLREQRAAHEEDLQRLQREKEAAWRELQAERAQLQG 1020
Cdd:pfam02463  486 LELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGG--RIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEER 563

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1021 QLQQEREELLARMEAEKE---ELSEEIAALQQERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSL------AAIS 1091
Cdd:pfam02463  564 QKLVRALTELPLGARKLRlliPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTEltklkeSAKA 643

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1092 LEMERQKRDAQSRQEQDRNTVNALTSELRDLRAQLEEATAAHAQQVKELQEQTGNLGRQREACMREAEELRTQLRLLEDT 1171
Cdd:pfam02463  644 KESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELL 723

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1172 RDGLRRELLEAQRKVRDSQDSSEAHRQEASELRRSLSEgtKEREALRRSNEELRTAVKKAESERISLKLANEDKEQKLAL 1251
Cdd:pfam02463  724 ADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEE--KEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEE 801

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1252 LEEARMSVAKEagelraslqEVERSRLEARRELQELRRQMKTLDSDNGRLGRELADLQSRLALGERTEKESRREVLGLRQ 1331
Cdd:pfam02463  802 ELRALEEELKE---------EAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQEL 872

                          730       740       750
                   ....*....|....*....|....*....|....*
gi 1958776745 1332 KVLKGESSLEALKQELQGSQRKLQEQEAEFRARER 1366
Cdd:pfam02463  873 LLKEEELEEQKLKDELESKEEKEKEEKKELEEESQ 907
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
761-1311 1.69e-08

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 59.93  E-value: 1.69e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  761 IAQLEEEKAALLGRQQQAEHATSLaVEKQERLEQLRLEQEVERQGLEG-SLCVAEQAREALGQQILVLRSERSHLQEQVA 839
Cdd:COG4913    234 FDDLERAHEALEDAREQIELLEPI-RELAERYAAARERLAELEYLRAAlRLWFAQRRLELLEAELEELRAELARLEAELE 312

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  840 QLSRQLNGRDQELDQALRE-SQRQVEALERAAREKEAMAKERAGLAVQLAAAEREGRTLSEEtirLRLEKEALESSLFDV 918
Cdd:COG4913    313 RLEARLDALREELDELEAQiRGNGGDRLEQLEREIERLERELEERERRRARLEALLAALGLP---LPASAEEFAALRAEA 389

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  919 QRQLAQLEARREQLEADSQALLLAKETLTGELAGLRQQVTATEEKaaldKELMTQKLVQAEREtqasLREQRAAHEEDLQ 998
Cdd:COG4913    390 AALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERR----KSNIPARLLALRDA----LAEALGLDEAELP 461

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  999 RLQ-----REKEAAWRElQAERA-------------------------QLQGQLQQEREELLARmeaekeelseeiAALQ 1048
Cdd:COG4913    462 FVGelievRPEEERWRG-AIERVlggfaltllvppehyaaalrwvnrlHLRGRLVYERVRTGLP------------DPER 528

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1049 QERDEGLLLAEsekqqaLSLKESEKTALSEKLMGTRHSLA-------------AISLE-MERQKRDAQSRQEQDRNTVN- 1113
Cdd:COG4913    529 PRLDPDSLAGK------LDFKPHPFRAWLEAELGRRFDYVcvdspeelrrhprAITRAgQVKGNGTRHEKDDRRRIRSRy 602

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1114 -------ALTSELRDLRAQLEEATAAHAQQVKELQEQTGNLGRQREACMREAEELRTQLRLledtrDGLRRELLEAQRKV 1186
Cdd:COG4913    603 vlgfdnrAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDV-----ASAEREIAELEAEL 677

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1187 RDSQDSSeahrQEASELRRSLSEGTKEREALRRSNEELRTAVKKAESERISLKLANEDKEQKLALLEEARMSVAKEAGEL 1266
Cdd:COG4913    678 ERLDASS----DDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEE 753

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*
gi 1958776745 1267 RASLQEVERSRLEARRELQElrrQMKTLDSDNGRLGRELADLQSR 1311
Cdd:COG4913    754 RFAAALGDAVERELRENLEE---RIDALRARLNRAEEELERAMRA 795
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
872-1428 1.91e-08

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 59.67  E-value: 1.91e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  872 EKEAMAKERAGLAVQLAAAEREGRTLSEETIRLRLEKEALESSLFDVQRQLAQLEARREQLEadsqalllakeTLTGELA 951
Cdd:PRK02224   193 KAQIEEKEEKDLHERLNGLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERREELE-----------TLEAEIE 261

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  952 GLRQQVTATE-EKAALDKELMTQKlvqAERETQASLREQRAAhEEDLQRLQREKEAAWRE-LQAERAQLQGQLQQEReel 1029
Cdd:PRK02224   262 DLRETIAETErEREELAEEVRDLR---ERLEELEEERDDLLA-EAGLDDADAEAVEARREeLEDRDEELRDRLEECR--- 334

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1030 larmeaekeelseeiAALQQERDEglllAESEKQQALSLKESEKTAlseklmgtRHSLAAISLEMERQKRDAQSRQEQdr 1109
Cdd:PRK02224   335 ---------------VAAQAHNEE----AESLREDADDLEERAEEL--------REEAAELESELEEAREAVEDRREE-- 385

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1110 ntVNALTSELRDLRAQLEEATAAHAQQVKELQEQTGNLGRQREacmrEAEELRTQLRLLEDTRDGlRRELLEAQR----- 1184
Cdd:PRK02224   386 --IEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELRE----REAELEATLRTARERVEE-AEALLEAGKcpecg 458

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1185 -KVRDSQ--DSSEAHRQEASELRRSLSEGTKEREALRR---SNEELRTAVKKAESERISLKLANEDKEQKLALLEEARMS 1258
Cdd:PRK02224   459 qPVEGSPhvETIEEDRERVEELEAELEDLEEEVEEVEErleRAEDLVEAEDRIERLEERREDLEELIAERRETIEEKRER 538

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1259 VA---KEAGELRASLQEVERSRLEARRELQELRRQMKTLDSDNGRLGRE---LADLQSRLALGErtekESRREVLGLRQK 1332
Cdd:PRK02224   539 AEelrERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERiesLERIRTLLAAIA----DAEDEIERLREK 614

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1333 vlkgesslealKQELQGSQRKLQEQEAEFRARERGLLGSLEEARGAEKKllDSARSLELRLEGVRAETSELGLRLSAAEG 1412
Cdd:PRK02224   615 -----------REALAELNDERRERLAEKRERKRELEAEFDEARIEEAR--EDKERAEEYLEQVEEKLDELREERDDLQA 681

                          570
                   ....*....|....*.
gi 1958776745 1413 RAQGLEVELARVEAQR 1428
Cdd:PRK02224   682 EIGAVENELEELEELR 697
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 610-849 1.98e-08

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 58.62  E-value: 1.98e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  610 LSHSLQVAQQQAEDLRQELEKLQAAQEELRRQHTQLEDQQEDTVQEGARARRELERSHRQLEQLEVKRSGLTKELVEVRE 689
Cdd:COG4942     11 LALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEK 90

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  690 ALscAVLQRDvLQTEKAEVAEALTKAEAGRAQLELSVTKLRAEEASLRDSLSKMSALNESLAQDKLELNRLIAQLEEEKA 769
Cdd:COG4942     91 EI--AELRAE-LEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRA 167

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  770 ALLGRQQQAEHATSLAVEKQERLEQLRLEQEVERQGLEGSLCVAEQAREALGQQILVLRSERSHLQEQVAQLSRQLNGRD 849
Cdd:COG4942    168 ELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAG 247
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
615-1179 2.38e-08

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 59.28  E-value: 2.38e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  615 QVAQQQAEDLRQELEKLQAAQEELRRQHTQLEDQQEDTVQEGARARRELERSHRQLEQLEVkrsgLTKELVEVREALSCA 694
Cdd:PRK02224   195 QIEEKEEKDLHERLNGLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERREELET----LEAEIEDLRETIAET 270

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  695 vlqrdvlQTEKAEVAEALTKAEAGRAQLELSVTKLRAEEASLRDSLSKMSALNESLAQDKLELNRliaQLEEEKAALLGR 774
Cdd:PRK02224   271 -------EREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRD---RLEECRVAAQAH 340

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  775 QQQAEHATSLAVEKQERLEQLRLEQEVERQGLegslcvaEQAREALGQQilvlRSERSHLQEQVAQLSRQLNGRDQELDQ 854
Cdd:PRK02224   341 NEEAESLREDADDLEERAEELREEAAELESEL-------EEAREAVEDR----REEIEELEEEIEELRERFGDAPVDLGN 409

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  855 AlresqrqVEALERAAREKEAMAKERAGLAVQLAAAE---REGRTLSEE----TIRLRLEKEALESSLFDVQRQLAQLEA 927
Cdd:PRK02224   410 A-------EDFLEELREERDELREREAELEATLRTARervEEAEALLEAgkcpECGQPVEGSPHVETIEEDRERVEELEA 482

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  928 RREQLEADSQALLLAKETLTgELAGLRQQVTATEEKAALDKELMTQK--LVQAERETQASLREQRAAHEEDLQRlQREKE 1005
Cdd:PRK02224   483 ELEDLEEEVEEVEERLERAE-DLVEAEDRIERLEERREDLEELIAERreTIEEKRERAEELRERAAELEAEAEE-KREAA 560

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1006 AAWRELQAERAQLQGQLQQEREEL------LARMEAEKEELSEEIAALQ--QERDEGLLLAESEKQQALSLKESEKTALS 1077
Cdd:PRK02224   561 AEAEEEAEEAREEVAELNSKLAELkeriesLERIRTLLAAIADAEDEIErlREKREALAELNDERRERLAEKRERKRELE 640

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1078 EKLMGTRhslaaisLEMERQKRDaqsRQEQDRNTVNALTSELRDLRAQLEEATAAHAQQVKELQEQTGNLGRQREACMRe 1157
Cdd:PRK02224   641 AEFDEAR-------IEEAREDKE---RAEEYLEQVEEKLDELREERDDLQAEIGAVENELEELEELRERREALENRVEA- 709

                          570       580
                   ....*....|....*....|..
gi 1958776745 1158 AEELRTQLRLLEDTRDGLRREL 1179
Cdd:PRK02224   710 LEALYDEAEELESMYGDLRAEL 731
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1721-1984 2.44e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 59.57  E-value: 2.44e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1721 KVQSLTDALAQSSASLTSSQDKNLYLQKALSTCEHDRQVLQ-ERLDA-----------ARQALSEARRQSSSLGEQVQTL 1788
Cdd:COG1196    214 RYRELKEELKELEAELLLLKLRELEAELEELEAELEELEAElEELEAelaeleaeleeLRLELEELELELEEAQAEEYEL 293

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1789 RGELANLELQRGDAEGQLQQLQQVLRQRQEGEAVALRSVQKLQEERRLLQERLGSLQRALAQLEAEKRELERSALQLDKD 1868
Cdd:COG1196    294 LAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAE 373

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1869 RVALRKTLDKVEREKLRSHEDTLRLNAERGRLDRTLTGAELDLAEAQQQIQHLEAQVVEVLER--NHSPVQVEADEQHLE 1946
Cdd:COG1196    374 LAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEeeEEEEALEEAAEEEAE 453

                          250       260       270
                   ....*....|....*....|....*....|....*...
gi 1958776745 1947 LQQEVERLRSAQVRTERTLEARERAHRQRVSGLEEQVQ 1984
Cdd:COG1196    454 LEEEEEALLELLAELLEEAALLEAALAELLEELAEAAA 491
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 618-1443 2.57e-08

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 59.42  E-value: 2.57e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  618 QQQAEDLRQELEKLQAAQEELRRQHTQLEDQQEDTVQEGARARRELERSHRQLEQLEVKRSGLTKELVEVREALSCAVLQ 697
Cdd:pfam01576  102 QQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKLEEDILLLEDQNSKLSKERKLLEERISEFTSNLAEEEEKAKSLSKL 181

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  698 RDVLQTEKAEVAEALTKAEAGRAQLELSVTKLRAEEASLRDSLSKMSALNEslaqdklELNRLIAQLEEEKAALLGRQQQ 777
Cdd:pfam01576  182 KNKHEAMISDLEERLKKEEKGRQELEKAKRKLEGESTDLQEQIAELQAQIA-------ELRAQLAKKEEELQAALARLEE 254

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  778 AEHATSLAVEKQERLEQLRLEQEVERQGLEGSLCVAEQAREALGQQILVLRSE--------------RSHLQEQVAQLSR 843
Cdd:pfam01576  255 ETAQKNNALKKIRELEAQISELQEDLESERAARNKAEKQRRDLGEELEALKTEledtldttaaqqelRSKREQEVTELKK 334

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  844 QLNGRDQELDQALRESQRQ--------VEALERAAREKEAMAKERAGLAVQLAAAEREGRTLSEETIRLRLEKEALESSL 915
Cdd:pfam01576  335 ALEEETRSHEAQLQEMRQKhtqaleelTEQLEQAKRNKANLEKAKQALESENAELQAELRTLQQAKQDSEHKRKKLEGQL 414

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  916 FDVQRQLAQLEARREQLEADSQALLLAKETLTGELAGLRQQ-VTATEEKAALDKELM-TQKLVQAE-------------- 979
Cdd:pfam01576  415 QELQARLSESERQRAELAEKLSKLQSELESVSSLLNEAEGKnIKLSKDVSSLESQLQdTQELLQEEtrqklnlstrlrql 494

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  980 RETQASLREQRAAHEEDLQRLQREKEAAWRELQAERAQLQG-------------QLQQEREELLARMEAEKEELSEEIAA 1046
Cdd:pfam01576  495 EDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEdagtlealeegkkRLQRELEALTQQLEEKAAAYDKLEKT 574

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1047 ---LQQERDEGLLLAESEKQQALSLKESEKTAlsEKLMGTRHSLAAISLEmERQKRDAQSRQEQDRntVNALTSELRDLR 1123
Cdd:pfam01576  575 knrLQQELDDLLVDLDHQRQLVSNLEKKQKKF--DQMLAEEKAISARYAE-ERDRAEAEAREKETR--ALSLARALEEAL 649

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1124 AQLEEATAAHAQQVKELQE----------QTGNLGRQREACMREAEELRTQLRLLED----TRDGLRRELLEAQRKVRDS 1189
Cdd:pfam01576  650 EAKEELERTNKQLRAEMEDlvsskddvgkNVHELERSKRALEQQVEEMKTQLEELEDelqaTEDAKLRLEVNMQALKAQF 729

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1190 QDSSEAHRQEASELRRSLSEGTKEREALRrsnEELRTAVKKAESERISLKLANEDKEQKLALLEEARMSVAKEAGELRAS 1269
Cdd:pfam01576  730 ERDLQARDEQGEEKRRQLVKQVRELEAEL---EDERKQRAQAVAAKKKLELDLKELEAQIDAANKGREEAVKQLKKLQAQ 806

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1270 LQEVERSRLEARRELQELRRQMKTLDSDNGRLGRELADLQSRLALGERTEKESRREVLGLRQKVLKGESSLEALKQELQG 1349
Cdd:pfam01576  807 MKDLQRELEEARASRDEILAQSKESEKKLKNLEAELLQLQEDLAASERARRQAQQERDELADEIASGASGKSALQDEKRR 886

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1350 SQRKLQEQEAEfrarergllgsLEEARGAEKKLLDSARSLELRLEGVRAEtselglrLSAAEGRAQGLEVELARVEAQRR 1429
Cdd:pfam01576  887 LEARIAQLEEE-----------LEEEQSNTELLNDRLRKSTLQVEQLTTE-------LAAERSTSQKSESARQQLERQNK 948

                          890
                   ....*....|....
gi 1958776745 1430 VAEAQLGGLRSALR 1443
Cdd:pfam01576  949 ELKAKLQEMEGTVK 962
PTZ00121 PTZ00121
MAEBL; Provisional
 536-1111 4.21e-08

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 59.00  E-value: 4.21e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  536 QVQDMRGRYEASQDLLGSVRKQLSDSEGERRGLEEQLQRLRDQTATSVQAQEdaQREAQRLRSANEILSREKGNLSHSLQ 615
Cdd:PTZ00121  1225 KAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEE--ARKADELKKAEEKKKADEAKKAEEKK 1302

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  616 VAQQ---------QAEDLRQELEKLQAAQEELRRQHTQLEDQQEDTVQEGARARRELERSHRQLEQLEVKRSGLTKELVE 686
Cdd:PTZ00121  1303 KADEakkkaeeakKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADA 1382

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  687 VREALScAVLQRDVLQTEKAEV---AEALTKAEAGRAQLELSVTKL----RAEEASLRDSLSKMSALNESLAQDKLELNR 759
Cdd:PTZ00121  1383 AKKKAE-EKKKADEAKKKAEEDkkkADELKKAAAAKKKADEAKKKAeekkKADEAKKKAEEAKKADEAKKKAEEAKKAEE 1461

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  760 LIAQLEEEKAALLGRQQ-----QAEHATSLAVEKQERLEQLRLEQEVERQGLEgsLCVAEQAREALGQQilvlRSERSHL 834
Cdd:PTZ00121  1462 AKKKAEEAKKADEAKKKaeeakKADEAKKKAEEAKKKADEAKKAAEAKKKADE--AKKAEEAKKADEAK----KAEEAKK 1535

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  835 QEQVAQLSRQLNGRDQELDQALRESQRQVEALE-RAAREKEAMAKERAGLAVQLAAAE-REGRTLSEETIRLRLEKEALE 912
Cdd:PTZ00121  1536 ADEAKKAEEKKKADELKKAEELKKAEEKKKAEEaKKAEEDKNMALRKAEEAKKAEEARiEEVMKLYEEEKKMKAEEAKKA 1615

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  913 SSLFDVQRQLAQLEARREQLEADSQALllAKETLTGElaglrqQVTATEEKAALDKELMTQKLVQAERETQASLR--EQR 990
Cdd:PTZ00121  1616 EEAKIKAEELKKAEEEKKKVEQLKKKE--AEEKKKAE------ELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKaeEDE 1687

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  991 AAHEEDLQRLQREKEAA--WRELQAERAQLQGQLQQERE------ELLARMEAEKEELSEEIAALQQERDEGLLLAESEK 1062
Cdd:PTZ00121  1688 KKAAEALKKEAEEAKKAeeLKKKEAEEKKKAEELKKAEEenkikaEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEE 1767

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*....
gi 1958776745 1063 QQALSLKESEKTALSEKLmgtrhslaaislemerQKRDAQSRQEQDRNT 1111
Cdd:PTZ00121  1768 KKAEEIRKEKEAVIEEEL----------------DEEDEKRRMEVDKKI 1800
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1499-1985 4.27e-08

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 58.51  E-value: 4.27e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1499 EAVRDALRDFLQELRSAQRERDELRVQTSTLSQQLAEMEAERDHAASRAKQLQKAVAESEEawrsadrRLSGAQAELALQ 1578
Cdd:PRK02224   233 RETRDEADEVLEEHEERREELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEE-------ERDDLLAEAGLD 305

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1579 EesvrrsrrecratLDQMAVLER--SLQATESELRASQEKVnkmKATEVKLESDKRRLKEVLDASESRSIKLELQRRALE 1656
Cdd:PRK02224   306 D-------------ADAEAVEARreELEDRDEELRDRLEEC---RVAAQAHNEEAESLREDADDLEERAEELREEAAELE 369

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1657 GELQRSRLGLGDREAHAQALQDRVDSLQRQVADSEVKAGTLQLTVERLSGALAKVEESEGTLRSKVQSLTDALAQSSASL 1736
Cdd:PRK02224   370 SELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTARERVEEAEALL 449

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1737 tssqdknlylqkALSTCEHDRQVLQERLDAArqALSEARrqssslgEQVQTLRGELANLELQRGDAEgqlqqlqqVLRQR 1816
Cdd:PRK02224   450 ------------EAGKCPECGQPVEGSPHVE--TIEEDR-------ERVEELEAELEDLEEEVEEVE--------ERLER 500

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1817 QEGEAVALRSVQKLQEERRLLQERLGSLQRALAQLEAEKRELERSALQLDKDRVALRKTLDKVEREKLRSHEDTLRLNAE 1896
Cdd:PRK02224   501 AEDLVEAEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSK 580

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1897 RGRLDRTLTGAElDLAEAQQQIQHLEAQVVEVLERNHSPVQVEaDEQHLELQQEVERLR--SAQVRTERTLEARERahRQ 1974
Cdd:PRK02224   581 LAELKERIESLE-RIRTLLAAIADAEDEIERLREKREALAELN-DERRERLAEKRERKRelEAEFDEARIEEARED--KE 656

                          490
                   ....*....|.
gi 1958776745 1975 RVSGLEEQVQG 1985
Cdd:PRK02224   657 RAEEYLEQVEE 667
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1129-1353 4.53e-08

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 57.47  E-value: 4.53e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1129 ATAAHAQQVKELQEQTGNLGRQREACMREAEELRTQLRLLEDTRDGLRRELLEAQRKVRDSQDSSEAHRQEASELRRSLS 1208
Cdd:COG4942     14 AAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIA 93

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1209 EGTKEREALRRS-NEELRTAVKKAESERISLKLANEDKEQ---KLALLEEARMSVAKEAGELRASLQEVERSRLEARREL 1284
Cdd:COG4942     94 ELRAELEAQKEElAELLRALYRLGRQPPLALLLSPEDFLDavrRLQYLKYLAPARREQAEELRADLAELAALRAELEAER 173

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1958776745 1285 QELRRQMKTLDSDNGRLGRELADLQSRLALGERTEKESRREVLGLRQKVLKGESSLEALKQELQGSQRK 1353
Cdd:COG4942    174 AELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 766-1357 4.72e-08

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 58.44  E-value: 4.72e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  766 EEKAALLGRQQQAEHATSLAVEKQERLEQLRLEQEVERQGLEGSLCVAEQAREALGQQILVLRSERSHLQEQVAQLSRQL 845
Cdd:TIGR00618  163 KEKKELLMNLFPLDQYTQLALMEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSH 242

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  846 NGRDQELDQALRESQRQVEALERAAREKEAMAKERAglavqlAAAEREGRTLSEETIRLRLEKEALESSLFDVQRQLAQL 925
Cdd:TIGR00618  243 AYLTQKREAQEEQLKKQQLLKQLRARIEELRAQEAV------LEETQERINRARKAAPLAAHIKAVTQIEQQAQRIHTEL 316

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  926 EARREQLEadsqalllakETLTGELAGLRQQVTATEEKAALDKELMTQKLVQAERETQASLREQRAAHEEDLQRL---QR 1002
Cdd:TIGR00618  317 QSKMRSRA----------KLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQHIhtlQQ 386

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1003 EKEAAWRELQAErAQLQGQLQQEREELLARMEAEKEELSEEIAA-----LQQERDEGLLLAESEKQQALSLKESEKTALS 1077
Cdd:TIGR00618  387 QKTTLTQKLQSL-CKELDILQREQATIDTRTSAFRDLQGQLAHAkkqqeLQQRYAELCAAAITCTAQCEKLEKIHLQESA 465

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1078 EKLMGTRHSLA---AISLEMERQKRDAQSRQEQDRNTVNALTSELRDLRAQLEEATAAHAQQ--VKELQEQTGNLGRQRE 1152
Cdd:TIGR00618  466 QSLKEREQQLQtkeQIHLQETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQDIDNPGPLTrrMQRGEQTYAQLETSEE 545

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1153 ACMREAEELRTQLRLLEDTRDGLRRELLEAQRKVRDSQDSSEAHRQEASELRRSLSEGTKEREALR-RSNEELRTAVKKA 1231
Cdd:TIGR00618  546 DVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLAcEQHALLRKLQPEQ 625

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1232 ESERISLKLANEDKEQKLALLEEARMSVAKEAGELRASLQEVERSRLEARRELQELRRQMKTLDSDNGRLGRELADLQSR 1311
Cdd:TIGR00618  626 DLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALSIRVLPKELLASRQLALQKMQSEKEQLTYWKEMLAQCQTL 705

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*.
gi 1958776745 1312 LALGERTEKESRREVLGLRQKVLKGESSLEALKQELQGSQRKLQEQ 1357
Cdd:TIGR00618  706 LRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQ 751
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
830-1364 7.47e-08

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 57.74  E-value: 7.47e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  830 ERSHLQEQVAQLSRQLNGRDQELDQALRESQRQVEALERAAREKEAMAKERAGLAVqLAAAEREGRTLSEETIRlrlEKE 909
Cdd:PRK02224   200 EEKDLHERLNGLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERREELET-LEAEIEDLRETIAETER---ERE 275

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  910 ALESSLFDVQRQLAQLEARREQL-------EADSQALLLAKETLTGELAGLRQqvtateekaaldkELMTQKLVQAERET 982
Cdd:PRK02224   276 ELAEEVRDLRERLEELEEERDDLlaeagldDADAEAVEARREELEDRDEELRD-------------RLEECRVAAQAHNE 342

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  983 QA-SLREQRAAHEEDLQRLQREKEAAWRELQAERAQLQgqlqqEREELLARMEAEKEELSEEIAALQQERDEglllAESE 1061
Cdd:PRK02224   343 EAeSLREDADDLEERAEELREEAAELESELEEAREAVE-----DRREEIEELEEEIEELRERFGDAPVDLGN----AEDF 413

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1062 kqqaLSLKESEKTALSEKLMGTRHSL--AAISLEMERQKRDA---------------QSRQEQDRNTVNALTSELRDLRA 1124
Cdd:PRK02224   414 ----LEELREERDELREREAELEATLrtARERVEEAEALLEAgkcpecgqpvegsphVETIEEDRERVEELEAELEDLEE 489

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1125 QLEEATAAH---------AQQVKELQEQTGNLGRQREACMREAEELRTQLRLLEDTRDGLRRELLEAQRKVRDSQDSSEA 1195
Cdd:PRK02224   490 EVEEVEERLeraedlveaEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEE 569

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1196 HRQEASELRRSLSEGTKEREALRRSnEELRTAVKKAESERISLKlaneDKEQKLALLEEARMSVAKEAGELRASLQ-EVE 1274
Cdd:PRK02224   570 AREEVAELNSKLAELKERIESLERI-RTLLAAIADAEDEIERLR----EKREALAELNDERRERLAEKRERKRELEaEFD 644

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1275 RSRLE-ARRELQELRRQMKTLDSDNGRLGRELADLQSRLAlGERTEKESRREVLGLRQKVLKGESSLEALKQELQGSQRK 1353
Cdd:PRK02224   645 EARIEeAREDKERAEEYLEQVEEKLDELREERDDLQAEIG-AVENELEELEELRERREALENRVEALEALYDEAEELESM 723

                          570
                   ....*....|.
gi 1958776745 1354 LQEQEAEFRAR 1364
Cdd:PRK02224   724 YGDLRAELRQR 734
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 564-770 8.37e-08

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 56.70  E-value: 8.37e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  564 ERRGLEEQLQRLRDQTATSVQAQEDAQREAQRLRSANEILSREKGNLSHSLQVAQQQAEDLRQELEKLQAAQEELRRQHT 643
Cdd:COG4942     21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELE 100

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  644 QLEDQQEDTVQEGARARR--------------ELERSHRQLEQLEVKRSGLTKELVEVREALScavLQRDVLQTEKAEVA 709
Cdd:COG4942    101 AQKEELAELLRALYRLGRqpplalllspedflDAVRRLQYLKYLAPARREQAEELRADLAELA---ALRAELEAERAELE 177

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1958776745  710 EALTKAEAGRAQLELSVTKLRAEEASLRDSLSKMSALNESLAQDKLELNRLIAQLEEEKAA 770
Cdd:COG4942    178 ALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAA 238
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
605-1033 9.12e-08

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 57.47  E-value: 9.12e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  605 REKGNLSHSLQVAQQQAEDLRQELEKLQAAQEELRRQHTQLEDQQE--DTVQEGARARRELERSHRQLEQLEVKRsgltK 682
Cdd:COG4717     81 KEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQllPLYQELEALEAELAELPERLEELEERL----E 156

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  683 ELVEVREALSCAVLQRDVLQTEKAEVAEALTKAEAGR-AQLELSVTKLRAEEASLRDSLSKMSALNESLAQDKLELNRLI 761
Cdd:COG4717    157 ELRELEEELEELEAELAELQEELEELLEQLSLATEEElQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENEL 236

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  762 AQLEEEKAALLGRQQQAEHATSLAvekqerLEQLRLEQEVERQGLEGSLCVAEQAREALGQQILVLRSERSHLQEQVAQL 841
Cdd:COG4717    237 EAAALEERLKEARLLLLIAAALLA------LLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQAL 310

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  842 SRQLNGRDQELDQALRESQRQVEALERAAREKEAMAKERAGLAVQLAAAEREGRTLSEETIRLRLEKEALESSLFDVQRQ 921
Cdd:COG4717    311 PALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIAALLAEAGVEDEEELRAA 390

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  922 LAQLEARREQLEadsqALLLAKETLTGELAGLRQQVTATEEKAALDKELMTQKLVQAERETQASLREQRAAHEEDLQRLQ 1001
Cdd:COG4717    391 LEQAEEYQELKE----ELEELEEQLEELLGELEELLEALDEEELEEELEELEEELEELEEELEELREELAELEAELEQLE 466

                          410       420       430
                   ....*....|....*....|....*....|..
gi 1958776745 1002 REKEAAwrELQAERAQLQGQLQQEREELLARM 1033
Cdd:COG4717    467 EDGELA--ELLQELEELKAELRELAEEWAALK 496
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 592-1001 1.60e-07

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 56.88  E-value: 1.60e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  592 EAQRLRSANEILSREKGNLSHSLQVAQQQAEDLRQELEKLQAAQEELRRQHTQLEDQQeDTVQEGARARRELERSHRQLE 671
Cdd:COG3096    279 ERRELSERALELRRELFGARRQLAEEQYRLVEMARELEELSARESDLEQDYQAASDHL-NLVQTALRQQEKIERYQEDLE 357

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  672 QLEVK-------RSGLTKELVEVREALSCAVLQRDVLQTEKAEVAEALTKAEAGRAQLELSVTKLRAEEAslrdsLSKMS 744
Cdd:COG3096    358 ELTERleeqeevVEEAAEQLAEAEARLEAAEEEVDSLKSQLADYQQALDVQQTRAIQYQQAVQALEKARA-----LCGLP 432

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  745 ALNESLAQDKLElnRLIAQLEEEKAALLGRQQQAEHATSLAVEKQERLEQLR-LEQEVERQGlegslcVAEQAREALGQQ 823
Cdd:COG3096    433 DLTPENAEDYLA--AFRAKEQQATEEVLELEQKLSVADAARRQFEKAYELVCkIAGEVERSQ------AWQTARELLRRY 504

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  824 ilvlrSERSHLQEQVAQLSRQLngrdQELDQALRESQRQVEALERAAREKEAMAKERAGLAVQLAAAEREGRTLSEETIR 903
Cdd:COG3096    505 -----RSQQALAQRLQQLRAQL----AELEQRLRQQQNAERLLEEFCQRIGQQLDAAEELEELLAELEAQLEELEEQAAE 575

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  904 LRLEKEALesslfdvQRQLAQLEARREQLEADSQALLLAKETLTgelaGLRQQVTATEEKAALDKELMtQKLVQAERETQ 983
Cdd:COG3096    576 AVEQRSEL-------RQQLEQLRARIKELAARAPAWLAAQDALE----RLREQSGEALADSQEVTAAM-QQLLEREREAT 643

                          410       420
                   ....*....|....*....|.
gi 1958776745  984 AS---LREQRAAHEEDLQRLQ 1001
Cdd:COG3096    644 VErdeLAARKQALESQIERLS 664
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
619-1164 2.89e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 56.08  E-value: 2.89e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  619 QQAEDLRQELEKLQAAQEEL---RRQHTQLED-----------QQEDTVQEGARARRELERSHRQLEQLEVKRSGLTKEL 684
Cdd:COG4913    225 EAADALVEHFDDLERAHEALedaREQIELLEPirelaeryaaaRERLAELEYLRAALRLWFAQRRLELLEAELEELRAEL 304

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  685 VEVREALSCAVLQRDVLQTEKAEVAEALtkAEAGRAQLElsvtKLRAEEASLRDSLSKMSALNESLAQDkleLNRLIAQL 764
Cdd:COG4913    305 ARLEAELERLEARLDALREELDELEAQI--RGNGGDRLE----QLEREIERLERELEERERRRARLEAL---LAALGLPL 375

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  765 EEEKAALLGRQQQAEHATSLAVEKQERLEQLRLEQEVERQGLegslcvaEQAREALGQQILVLRSERS----HLQEQVAQ 840
Cdd:COG4913    376 PASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDL-------RRELRELEAEIASLERRKSnipaRLLALRDA 448

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  841 LSRQLNGRDQELDQA-----LRESQRQVE-ALERA------------AREKEAMAKERA--------GLAVQLAAAEREG 894
Cdd:COG4913    449 LAEALGLDEAELPFVgelieVRPEEERWRgAIERVlggfaltllvppEHYAAALRWVNRlhlrgrlvYERVRTGLPDPER 528

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  895 RTLSEETIRLRLEKEalESSLFD-VQRQLAQLEARR-----EQLEADSQALllakeTLTGELAG------------LRQQ 956
Cdd:COG4913    529 PRLDPDSLAGKLDFK--PHPFRAwLEAELGRRFDYVcvdspEELRRHPRAI-----TRAGQVKGngtrhekddrrrIRSR 601

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  957 ----VTATEEKAALDKEL--MTQKLVQAERETQAsLREQRAAHEEDLQRLQREKEAAWRELQAERAQLQ-GQLQQEREEL 1029
Cdd:COG4913    602 yvlgFDNRAKLAALEAELaeLEEELAEAEERLEA-LEAELDALQERREALQRLAEYSWDEIDVASAEREiAELEAELERL 680

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1030 LArmeaekeeLSEEIAALQQERDEglllAESEKQQAlslkESEKTALSEKLMGTRHSLAAIslemERQKRDAQSRQEQDR 1109
Cdd:COG4913    681 DA--------SSDDLAALEEQLEE----LEAELEEL----EEELDELKGEIGRLEKELEQA----EEELDELQDRLEAAE 740

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1958776745 1110 NTVNALTSELRDLRAQLEEATAAHAQQVKELQEQTGNLGRQREACMREAEELRTQ 1164
Cdd:COG4913    741 DLARLELRALLEERFAAALGDAVERELRENLEERIDALRARLNRAEEELERAMRA 795
PTZ00121 PTZ00121
MAEBL; Provisional
 1127-1891 3.47e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 55.92  E-value: 3.47e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1127 EEATAAHAQQVKELQEQTGNLGRQREAcmREAEELRT--QLRLLEDTRDGLRRELLEAQRKVRDSQDSSEAHRQEasELR 1204
Cdd:PTZ00121  1101 EEAKKTETGKAEEARKAEEAKKKAEDA--RKAEEARKaeDARKAEEARKAEDAKRVEIARKAEDARKAEEARKAE--DAK 1176

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1205 RSlsEGTKEREALRRSnEELRTA--VKKAESERislKLANEDKEQKLALLEEARmsvakeagelraSLQEVERSRlEARR 1282
Cdd:PTZ00121  1177 KA--EAARKAEEVRKA-EELRKAedARKAEAAR---KAEEERKAEEARKAEDAK------------KAEAVKKAE-EAKK 1237

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1283 ELQELRRQMKTLDSDNGRLGREladlqSRLALGERTEKESRREVLGLRQKVLKGESSLEAlkQELQGSQRKLQEQEAEFR 1362
Cdd:PTZ00121  1238 DAEEAKKAEEERNNEEIRKFEE-----ARMAHFARRQAAIKAEEARKADELKKAEEKKKA--DEAKKAEEKKKADEAKKK 1310

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1363 ArergllgslEEARGAEKklldsarsLELRLEGVRAETSELGLRlsaAEGRAQGLEVELARVEAQRRVAEAQLGGLRSAL 1442
Cdd:PTZ00121  1311 A---------EEAKKADE--------AKKKAEEAKKKADAAKKK---AEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAE 1370

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1443 RRGLGLGRVSSSPAREAPAGGSGDGLSSPSPlEYSPRSQPPSPGPVASPAPPDLDPEAVRDALRDFLQELRSAQRERDEL 1522
Cdd:PTZ00121  1371 KKKEEAKKKADAAKKKAEEKKKADEAKKKAE-EDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEA 1449

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1523 RVQTStlSQQLAEMEAERDHAASRAKQLQKAVAESEEAWRSADRrlsgaqAELALQEESVRRSRRECRATLDQMAVLERS 1602
Cdd:PTZ00121  1450 KKKAE--EAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKK------AEEAKKKADEAKKAAEAKKKADEAKKAEEA 1521

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1603 LQAteSELRASQEKvnkMKATEVKLESDKRRLKEVLDASESRsiKLELQRRALEGELQRSRLGLGDREAH-AQALQDRVD 1681
Cdd:PTZ00121  1522 KKA--DEAKKAEEA---KKADEAKKAEEKKKADELKKAEELK--KAEEKKKAEEAKKAEEDKNMALRKAEeAKKAEEARI 1594

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1682 SLQRQVADSEVKAGTLQLTVERLSGALAKVEESEGTLRSKVQSLTDALAQSsasltssQDKNLYLQKAlstcEHDRQVLQ 1761
Cdd:PTZ00121  1595 EEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEE-------KKKAEELKKA----EEENKIKA 1663

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1762 ERLdaARQALSEARRQSsslgeqvqtlrgELANLELQRGDAEGQLQQLQQVLRQRQEGEAVALRSVQKLQEERRLLQERL 1841
Cdd:PTZ00121  1664 AEE--AKKAEEDKKKAE------------EAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENK 1729

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1958776745 1842 GSLQRALAQLEAEKRELERSAL-QLDKDRVALRKTLDKVEREKLRSHEDTL 1891
Cdd:PTZ00121  1730 IKAEEAKKEAEEDKKKAEEAKKdEEEKKKIAHLKKEEEKKAEEIRKEKEAV 1780
PTZ00121 PTZ00121
MAEBL; Provisional
 1209-1953 6.92e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 54.76  E-value: 6.92e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1209 EGTKEREALRRSNEELRTAVKKAESERISLKLANEDKEQKLALLEEARMSVAKEAGELRASLQEVERS----RLEARREL 1284
Cdd:PTZ00121  1057 EGKAEAKAHVGQDEGLKPSYKDFDFDAKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAedarKAEEARKA 1136

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1285 QELRR---QMKTLDSDNGRLGRELADLQ----SRLALGERTEKESRREVLGLR-QKVLKGESSLEALKQELQGSQRKLQE 1356
Cdd:PTZ00121  1137 EDARKaeeARKAEDAKRVEIARKAEDARkaeeARKAEDAKKAEAARKAEEVRKaEELRKAEDARKAEAARKAEEERKAEE 1216

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1357 QEAEFRARERGLLGSLEEAR--GAEKKLLDSARSLELRLEGVRAETSELGLRLSAAEGRAQGLEVELARVEAQRRVAEAQ 1434
Cdd:PTZ00121  1217 ARKAEDAKKAEAVKKAEEAKkdAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAK 1296

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1435 lgglRSALRRGLGLGRVSSSPAREAPAGGSGDGLSSPSPLEYSPRSQPPSPGPVASPAppdlDPEAVRDALRDFLQELRS 1514
Cdd:PTZ00121  1297 ----KAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKA----EAEAAADEAEAAEEKAEA 1368

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1515 AQRERDELRVQTSTLSQQlAEMEAERDHAASRAKQLQKAVAE---SEEAWRSADRrlSGAQAELALQEESVRRSRRECRA 1591
Cdd:PTZ00121  1369 AEKKKEEAKKKADAAKKK-AEEKKKADEAKKKAEEDKKKADElkkAAAAKKKADE--AKKKAEEKKKADEAKKKAEEAKK 1445

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1592 TLDQMAVLERSLQATESELRASQEKvnkmKATEVKLESD-KRRLKEVLDASESRSIKLELQRRALEG-----ELQRSRLG 1665
Cdd:PTZ00121  1446 ADEAKKKAEEAKKAEEAKKKAEEAK----KADEAKKKAEeAKKADEAKKKAEEAKKKADEAKKAAEAkkkadEAKKAEEA 1521

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1666 LGDREAHAQALQDRVDSLQRqvADSEVKAGTLQLTVE-RLSGALAKVEESEGTLRSKVQSLTDA-LAQSSASLTSSQDKN 1743
Cdd:PTZ00121  1522 KKADEAKKAEEAKKADEAKK--AEEKKKADELKKAEElKKAEEKKKAEEAKKAEEDKNMALRKAeEAKKAEEARIEEVMK 1599

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1744 LYLQKALSTCEHDRQVLQERLDAARQALSEARRQSSslgEQVQTLRGELANLELQRGDAEGQLQQLQQVLRQRQEGEAVA 1823
Cdd:PTZ00121  1600 LYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKV---EQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKK 1676

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1824 LRSVQKLQEERRLLQERLGSLQRALAQLEAEKRELERSALQLDKDRVALRKTLDKVEREKLRSHEDtlRLNAERGRLDrt 1903
Cdd:PTZ00121  1677 AEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEED--KKKAEEAKKD-- 1752

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1904 ltgaELDLAEAQQQIQHLEAQVVEVLERNHSPVQVEADEQHLELQQEVER 1953
Cdd:PTZ00121  1753 ----EEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDK 1798
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 850-1082 7.93e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 53.61  E-value: 7.93e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  850 QELDQALRESQRQVEALERAAREKEAMAKERAGLAVQLAAAEREGRTLSEETirlrlekEALESSLFDVQRQLAQLEARR 929
Cdd:COG4942     27 AELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQEL-------AALEAELAELEKEIAELRAEL 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  930 EQLEADSQALLLAKETLtGELAGLRQQVTATEEKAALDKELMTQKLVQAERETQASLREQRA---AHEEDLQRLQREKEA 1006
Cdd:COG4942    100 EAQKEELAELLRALYRL-GRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAelaALRAELEAERAELEA 178

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958776745 1007 AWRELQAERAQLQgQLQQEREELLARMEAEKEELSEEIAALQQERDEGLLLAESEKQQALSLKESEKTALSEKLMG 1082
Cdd:COG4942    179 LLAELEEERAALE-ALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGFAALKG 253
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
906-1444 1.36e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 53.77  E-value: 1.36e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  906 LEKEALESSLFDVQRQLAQLEARREQLEADSQALllakETLTGELAGLRQQVTATEEKAALDKELMTQKLVQAEREtQAS 985
Cdd:COG4913    218 LEEPDTFEAADALVEHFDDLERAHEALEDAREQI----ELLEPIRELAERYAAARERLAELEYLRAALRLWFAQRR-LEL 292

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  986 LREQRAAHEEDLQRLQREKEaawrELQAERAQLQGQLQQEREELLARMEAEKEELSEEIAALQQERDEGLLLAESEKQQA 1065
Cdd:COG4913    293 LEAELEELRAELARLEAELE----RLEARLDALREELDELEAQIRGNGGDRLEQLEREIERLERELEERERRRARLEALL 368

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1066 LSLKESEKT------ALSEKLMGTRHSLAAISLEMERQKRDAQSRQEQDRNTVNALTSELRDL--------------RAQ 1125
Cdd:COG4913    369 AALGLPLPAsaeefaALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLerrksniparllalRDA 448

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1126 LEEATAAHAQQVK---ELQEQtgnlgRQREACMREAEE--LRTQ-LRLLEDTRDglRRELLEA--QRKVRDSQDSSEAHR 1197
Cdd:COG4913    449 LAEALGLDEAELPfvgELIEV-----RPEEERWRGAIErvLGGFaLTLLVPPEH--YAAALRWvnRLHLRGRLVYERVRT 521

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1198 QEASELRRSLSEGT-------KEREALRRSNEEL--RTAVKKAESERislKLANEDKeqklALLEEARMSVAKEAGELRA 1268
Cdd:COG4913    522 GLPDPERPRLDPDSlagkldfKPHPFRAWLEAELgrRFDYVCVDSPE---ELRRHPR----AITRAGQVKGNGTRHEKDD 594

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1269 SLQEVE--------RSRLEA-RRELQELRRQMKTLDSDNGRLGRELADLQSRLALGERTEKES---------RREVLGLR 1330
Cdd:COG4913    595 RRRIRSryvlgfdnRAKLAAlEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSwdeidvasaEREIAELE 674

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1331 QK---VLKGESSLEALKQELQGSQRKLQEQEAEFRAReRGLLGSLEEARGAEKKLLDSARSLELRLEGVRAETSELGL-- 1405
Cdd:COG4913    675 AElerLDASSDDLAALEEQLEELEAELEELEEELDEL-KGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLee 753

                          570       580       590
                   ....*....|....*....|....*....|....*....
gi 1958776745 1406 RLSAAEGRAQGLEVElARVEAQRRVAEAQLGGLRSALRR 1444
Cdd:COG4913    754 RFAAALGDAVERELR-ENLEERIDALRARLNRAEEELER 791
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1195-1796 1.59e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 53.38  E-value: 1.59e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1195 AHRQEASELRRSLSEGTKEREALRRSNEE----LRTAVKKAESERISLKLANEDKEQKLALLEEARMSVAKEAGELRASL 1270
Cdd:COG4913    232 EHFDDLERAHEALEDAREQIELLEPIRELaeryAAARERLAELEYLRAALRLWFAQRRLELLEAELEELRAELARLEAEL 311

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1271 QEVERSRLEARRELQELRRQMKTLDsdngrlGRELADLQSRLALGERTEKESRREVLGLRQKvlkgessLEALKQELQGS 1350
Cdd:COG4913    312 ERLEARLDALREELDELEAQIRGNG------GDRLEQLEREIERLERELEERERRRARLEAL-------LAALGLPLPAS 378

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1351 QRKLQEQEAEFRARergllgsleeargaekklldsARSLELRLEGVRAETSELGLRLSAAEGRAQGLEVELARVEAQRRV 1430
Cdd:COG4913    379 AEEFAALRAEAAAL---------------------LEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSN 437

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1431 AEAQLGGLRSALRRGLGLgrvsssPAREAPAGGSgdgLSSPSPLEysPRSQPPSPGPVASPAPPDLDPEAVRDALRDFLQ 1510
Cdd:COG4913    438 IPARLLALRDALAEALGL------DEAELPFVGE---LIEVRPEE--ERWRGAIERVLGGFALTLLVPPEHYAAALRWVN 506

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1511 ELRSAQR-------ERDELRVQTSTLSQQLAEMEAERDHAASR------AKQLQKAVAESEEAWRSADRRLSgaQAELAL 1577
Cdd:COG4913    507 RLHLRGRlvyervrTGLPDPERPRLDPDSLAGKLDFKPHPFRAwleaelGRRFDYVCVDSPEELRRHPRAIT--RAGQVK 584

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1578 QEESVRRS--RRECRATL-------DQMAVLERSLQATESELRASQEKVNKMKATEVKLESDKRRLKEVLDASESRSIKL 1648
Cdd:COG4913    585 GNGTRHEKddRRRIRSRYvlgfdnrAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVA 664

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1649 ELQRRALEGELQRSRLGLGDreahaqalqDRVDSLQRQVAdsevkagTLQLTVERLSGALAKVEESEGTLRSKVQSLTDA 1728
Cdd:COG4913    665 SAEREIAELEAELERLDASS---------DDLAALEEQLE-------ELEAELEELEEELDELKGEIGRLEKELEQAEEE 728

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1958776745 1729 LAQSSASLTSSQDKnlylqkalsTCEHDRQVLQERLDAARQALSEaRRQSSSLGEQVQTLRGELANLE 1796
Cdd:COG4913    729 LDELQDRLEAAEDL---------ARLELRALLEERFAAALGDAVE-RELRENLEERIDALRARLNRAE 786
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
564-978 1.80e-06

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 53.23  E-value: 1.80e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  564 ERRGLEEQLQRLRDQT---ATSVQAQEDAQREAQRLRSANEILSREKGNLSHSLQVAQ--QQAEDLRQELEKLQAAQEEL 638
Cdd:COG4717     72 ELKELEEELKEAEEKEeeyAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPlyQELEALEAELAELPERLEEL 151

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  639 RRQHTQLEDQQEDTvqegARARRELERSHRQLEQLEVKRSGLT-KELVEVREALSCAVLQRDVLQTEKAEVAEALTKAEA 717
Cdd:COG4717    152 EERLEELRELEEEL----EELEAELAELQEELEELLEQLSLATeEELQDLAEELEELQQRLAELEEELEEAQEELEELEE 227

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  718 GRAQLELSVTKLRAEE-----------ASLRDSLSKMSALNESLAQDKLELNRLIAQLEEEKAALLGRQQQAEHATSLAV 786
Cdd:COG4717    228 ELEQLENELEAAALEErlkearlllliAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEEL 307

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  787 E---KQERLEQLRLEQEVERQGLEGSLCVAEQAREALGQQILVLRSERSHLQEQVAQLSRQLNGRDQELDQALRESQRQV 863
Cdd:COG4717    308 QalpALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIAALLAEAGVEDEEEL 387

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  864 EALERAAREKEAMAKERAGLAVQLAAAEREGRTLSEEtirlrLEKEALESSLFDVQRQLAQLEARREQLEADSQALLLAK 943
Cdd:COG4717    388 RAALEQAEEYQELKEELEELEEQLEELLGELEELLEA-----LDEEELEEELEELEEELEELEEELEELREELAELEAEL 462

                          410       420       430
                   ....*....|....*....|....*....|....*...
gi 1958776745  944 ETL--TGELAGLRQQV-TATEEKAALDKELMTQKLVQA 978
Cdd:COG4717    463 EQLeeDGELAELLQELeELKAELRELAEEWAALKLALE 500
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1505-1970 2.03e-06

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 53.14  E-value: 2.03e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1505 LRDFLQELRSAQRERDELRVQTSTLSQQLAEMEAERDHAASRAKQLQKAVAESEEAWRSADRRLsGAQAELALQEESVRR 1584
Cdd:PRK03918   219 LREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKV-KELKELKEKAEEYIK 297

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1585 SRRECRATLDQMAVLERSLQATESELRASQEKVNKMKATEVKLESDKRRLKEVLDASESRSIKLEL--QRRALEGELQRS 1662
Cdd:PRK03918   298 LSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELyeEAKAKKEELERL 377

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1663 RLGLGDR-----EAHAQALQDRVDSLQRQVADSEVKAGTLQLTVERLSGALAKVEESEGTLRSKVQSLTDALAQSSASLT 1737
Cdd:PRK03918   378 KKRLTGLtpeklEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCGRELTEEHRKELLEEY 457

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1738 SSQDKNLylQKALSTCEHDRQVLQERLDAARQALSEARRQSS--SLGEQVQTLRGELANLELQRGDAEGQLQQLQQVLRQ 1815
Cdd:PRK03918   458 TAELKRI--EKELKEIEEKERKLRKELRELEKVLKKESELIKlkELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLI 535

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1816 RQEGEAVALRS----VQKLQEERRLLQERLGSLQRALAQLEAEKRELERSALQLDKDRValrKTLDKVERE--KLRSHED 1889
Cdd:PRK03918   536 KLKGEIKSLKKelekLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERL---KELEPFYNEylELKDAEK 612

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1890 TL-RLNAERGRLDRTLTGAELDLAEAQQQIQHLEAQVVEVLERNHSPVQVEADEQHLELQQEVERLRSAQVRTERTLEAR 1968
Cdd:PRK03918   613 ELeREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEELREEYLELSRELAGLRAELEELEKRREEI 692


                   ..
gi 1958776745 1969 ER 1970
Cdd:PRK03918   693 KK 694
PRK10246 PRK10246
exonuclease subunit SbcC; Provisional
 561-1254 2.53e-06

exonuclease subunit SbcC; Provisional


Pssm-ID: 182330 [Multi-domain]  Cd Length: 1047  Bit Score: 52.88  E-value: 2.53e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  561 SEGERRGLEEQLQRLRDQTATSVQAQEDAQREAQRLRSANEiLSREKGNLSHSLQVAQQQAEDLRQELEKLQAAQEElRR 640
Cdd:PRK10246   214 TPEQVQSLTASLQVLTDEEKQLLTAQQQQQQSLNWLTRLDE-LQQEASRRQQALQQALAAEEKAQPQLAALSLAQPA-RQ 291

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  641 QHTQLEDQQEDTvqegararRELERSHRQLEQLEVKRSGLTKELVEVREalsCAVLQRDVLQTEKAEVAEALTKAEAGRA 720
Cdd:PRK10246   292 LRPHWERIQEQS--------AALAHTRQQIEEVNTRLQSTMALRARIRH---HAAKQSAELQAQQQSLNTWLAEHDRFRQ 360

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  721 qlelsvtklraeeasLRDSLSKMSALNESLAQDKLELNRLIAQLEEEKaallgRQQQAEHATSLAVEKQErleqlrleqe 800
Cdd:PRK10246   361 ---------------WNNELAGWRAQFSQQTSDREQLRQWQQQLTHAE-----QKLNALPAITLTLTADE---------- 410

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  801 verqglegslcvAEQAREALGQQiLVLRSERSHLQEQVAQLSRqlngRDQELDQALRESQRQVEALERAAREKEAMAKER 880
Cdd:PRK10246   411 ------------VAAALAQHAEQ-RPLRQRLVALHGQIVPQQK----RLAQLQVAIQNVTQEQTQRNAALNEMRQRYKEK 473

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  881 AGLAVQLAA-AEREGRTLSEETIRLRLEK------------------EALESSlfDVQRQLAQLEARREQLEADSQALLl 941
Cdd:PRK10246   474 TQQLADVKTiCEQEARIKDLEAQRAQLQAgqpcplcgstshpaveayQALEPG--VNQSRLDALEKEVKKLGEEGAALR- 550

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  942 aketltGELAGLRQQVT-ATEEKAALDKElmTQKLVQAERETQASLREQRAAHEeDLQRLQREKEAAWREL------QAE 1014
Cdd:PRK10246   551 ------GQLDALTKQLQrDESEAQSLRQE--EQALTQQWQAVCASLNITLQPQD-DIQPWLDAQEEHERQLrllsqrHEL 621

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1015 RAQLQGQLQQERE---ELLARMEAEKEELSEEIAALQQERDEGLLLAESEKQ-QALSLKESEKTALSEKLMGTRHSLAAI 1090
Cdd:PRK10246   622 QGQIAAHNQQIIQyqqQIEQRQQQLLTALAGYALTLPQEDEEASWLATRQQEaQSWQQRQNELTALQNRIQQLTPLLETL 701

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1091 SLEMERQKRDAQSRQEQDRNTVN---ALTSELRDLRAQLEEATAAHAQQVKELQEQTGNLGRQREACMREAEELRTQLRL 1167
Cdd:PRK10246   702 PQSDDLPHSEETVALDNWRQVHEqclSLHSQLQTLQQQDVLEAQRLQKAQAQFDTALQASVFDDQQAFLAALLDEETLTQ 781

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1168 LEDTRDGLRRELLEAQRKVRDSQDSSEAHRQEASELRRSLSEGTKEREALRRSNEELRTAVKKAESERISLKLANEDKEQ 1247
Cdd:PRK10246   782 LEQLKQNLENQRQQAQTLVTQTAQALAQHQQHRPDGLDLTVTVEQIQQELAQLAQQLRENTTRQGEIRQQLKQDADNRQQ 861


                   ....*..
gi 1958776745 1248 KLALLEE 1254
Cdd:PRK10246   862 QQALMQQ 868
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 533-1286 2.58e-06

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 53.03  E-value: 2.58e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  533 RQLQVQDMRGRYEASQDLLGSVRKQLSDSEgerRGLEEQlQRLRDQTATSVQAQEDAQR--------------EAQRLRS 598
Cdd:COG3096    373 AAEQLAEAEARLEAAEEEVDSLKSQLADYQ---QALDVQ-QTRAIQYQQAVQALEKARAlcglpdltpenaedYLAAFRA 448

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  599 ANEILSREKGNLSHSLQVAQQQAEDLRQELEKL-------------QAAQEELR--RQHTQLEDQQEDTVQEGARARREL 663
Cdd:COG3096    449 KEQQATEEVLELEQKLSVADAARRQFEKAYELVckiageversqawQTARELLRryRSQQALAQRLQQLRAQLAELEQRL 528

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  664 ERSH---RQLEQLEVKRSGLTKELVEVREALSCAVLQRDVLQTEKAEVAEALTKAEAGRAQLELSVTKLRAEEASLRDSL 740
Cdd:COG3096    529 RQQQnaeRLLEEFCQRIGQQLDAAEELEELLAELEAQLEELEEQAAEAVEQRSELRQQLEQLRARIKELAARAPAWLAAQ 608

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  741 SKMSALNESLAQdklelnrliaQLEEEKAALLGRQQQAEHATSLAVEKQERLEQ-LRLEQEVERQGLEGSlcvAEQAR-- 817
Cdd:COG3096    609 DALERLREQSGE----------ALADSQEVTAAMQQLLEREREATVERDELAARkQALESQIERLSQPGG---AEDPRll 675

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  818 ---EALGQQILVLRSERSHLQEQ---------------VAQLSR---QLNGRD-----------------------QELD 853
Cdd:COG3096    676 alaERLGGVLLSEIYDDVTLEDApyfsalygparhaivVPDLSAvkeQLAGLEdcpedlyliegdpdsfddsvfdaEELE 755

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  854 QA--LRESQRQ--------VEALERAAREK--EAMAKERAGLAVQLAAAEREGRTLSeetiRLRLEKEAL---------- 911
Cdd:COG3096    756 DAvvVKLSDRQwrysrfpeVPLFGRAAREKrlEELRAERDELAEQYAKASFDVQKLQ----RLHQAFSQFvgghlavafa 831

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  912 ---ESSLFDVQRQLAQLEARREQLEADSQALLLAKETLTGELAGLRQQVTateEKAALDKELMTQKLVQAERETQASLRE 988
Cdd:COG3096    832 pdpEAELAALRQRRSELERELAQHRAQEQQLRQQLDQLKEQLQLLNKLLP---QANLLADETLADRLEELREELDAAQEA 908

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  989 QR--AAHEEDLQRLQ------REKEAAWRELQAERAQLQGQLQQEREELLARMEAEKEELSEEIAALQQERDEGLLLAES 1060
Cdd:COG3096    909 QAfiQQHGKALAQLEplvavlQSDPEQFEQLQADYLQAKEQQRRLKQQIFALSEVVQRRPHFSYEDAVGLLGENSDLNEK 988

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1061 EKQQaLSLKESEKTALSEKLMGTRHSLAAISLEMErqkrDAQSRQEQDRNTVNALTSELRDLRAQL-EEATAAHAQQVKE 1139
Cdd:COG3096    989 LRAR-LEQAEEARREAREQLRQAQAQYSQYNQVLA----SLKSSRDAKQQTLQELEQELEELGVQAdAEAEERARIRRDE 1063

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1140 LQEQTGN-------LGRQREACMREAEELRTQLRLLEDTRDGLRRELLEA-------QRKVRDSQDSSEAHR-----QEA 1200
Cdd:COG3096   1064 LHEELSQnrsrrsqLEKQLTRCEAEMDSLQKRLRKAERDYKQEREQVVQAkagwcavLRLARDNDVERRLHRrelayLSA 1143

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1201 SELrRSLSEgtkerEALRrsneELRTAVKKAESERISLKLANEDK--EQKLA--------LLEEARMSVAKEAGELRASL 1270
Cdd:COG3096   1144 DEL-RSMSD-----KALG----ALRLAVADNEHLRDALRLSEDPRrpERKVQfyiavyqhLRERIRQDIIRTDDPVEAIE 1213

                          890
                   ....*....|....*..
gi 1958776745 1271 Q-EVERSRLEARRELQE 1286
Cdd:COG3096   1214 QmEIELARLTEELTSRE 1230
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 569-1434 3.41e-06

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 52.36  E-value: 3.41e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  569 EEQLQRLRDQTaTSVQAQEDAQRE------------AQRLRSANEILSR--EKGNLSHSLQVAQQQAEDLRQELEklQAA 634
Cdd:TIGR00606  216 KEKACEIRDQI-TSKEAQLESSREivksyeneldplKNRLKEIEHNLSKimKLDNEIKALKSRKKQMEKDNSELE--LKM 292

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  635 QEELRRQHTQLEDQQEDTVQEGARARRELERSHRQLEQLEVKRSGLTKELVEVREALSCAVLQRDVLQtEKAEVAEALTK 714
Cdd:TIGR00606  293 EKVFQGTDEQLNDLYHNHQRTVREKERELVDCQRELEKLNKERRLLNQEKTELLVEQGRLQLQADRHQ-EHIRARDSLIQ 371

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  715 AEAGRAQL---------ELSVTKLRAEEASLRDSLSKMSALNESLAQDKLELNRLIAQLEEEKAALLGRQQQAEhaTSLA 785
Cdd:TIGR00606  372 SLATRLELdgfergpfsERQIKNFHTLVIERQEDEAKTAAQLCADLQSKERLKQEQADEIRDEKKGLGRTIELK--KEIL 449

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  786 VEKQERLEQLRLEQEVERQGLEGSLCVAEQAREALGQ--------QILVLRSERSHLQEQVAQLSRQLNGRDQELDQALR 857
Cdd:TIGR00606  450 EKKQEELKFVIKELQQLEGSSDRILELDQELRKAERElskaeknsLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNH 529

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  858 E--SQRQVEALERAAREKEAMAKE----RAGLAVQLAAAEREGRTLSEETIRLRLEKEALESSLFDVQRQLAQLEARREQ 931
Cdd:TIGR00606  530 HttTRTQMEMLTKDKMDKDEQIRKiksrHSDELTSLLGYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNH 609

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  932 LEADsqalllaKETLTGELAGLRQQVTATEEKAALDKEL-MTQKLVQAERETQASLREQRAAHEEDLQRLQREKEAAW-- 1008
Cdd:TIGR00606  610 INNE-------LESKEEQLSSYEDKLFDVCGSQDEESDLeRLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSCCpv 682

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1009 --RELQAErAQLQgQLQQEREELLARMEAEKEELSEEIAALQQERDEGLLLAESeKQQALSLKESEKTALSEKLMGTRHS 1086
Cdd:TIGR00606  683 cqRVFQTE-AELQ-EFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPG-RQSIIDLKEKEIPELRNKLQKVNRD 759

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1087 LAAISLEMERQKRDAQSRQEQDRNTVNALT--SELRDLRAQLEEATAAHAQQVKELQEQTGNLGRQreacmreaeELRTQ 1164
Cdd:TIGR00606  760 IQRLKNDIEEQETLLGTIMPEEESAKVCLTdvTIMERFQMELKDVERKIAQQAAKLQGSDLDRTVQ---------QVNQE 830

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1165 LRLLEDTRDGLRRELLEAQRKVRDSQDSSEAHRQEASEL---RRSLSEGTKEREALRRSNEELRTAVKkaeseriSLKLA 1241
Cdd:TIGR00606  831 KQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNELkseKLQIGTNLQRRQQFEEQLVELSTEVQ-------SLIRE 903

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1242 NEDKEQKLALLEEARMSVAKEAGELRASLQEverSRLEARRELQELRRQMKTLDSDNGRLGRELADLQSRLALGERTEKE 1321
Cdd:TIGR00606  904 IKDAKEQDSPLETFLEKDQQEKEELISSKET---SNKKAQDKVNDIKEKVKNIHGYMKDIENKIQDGKDDYLKQKETELN 980

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1322 SRREVLGLRQKVLKG-ESSLEALKQELQGS-QRKLQEQEAEFRARERGLLGSLEEARGAEKKLLDSARSLELRLE--GVR 1397
Cdd:TIGR00606  981 TVNAQLEECEKHQEKiNEDMRLMRQDIDTQkIQERWLQDNLTLRKRENELKEVEEELKQHLKEMGQMQVLQMKQEhqKLE 1060

                          890       900       910
                   ....*....|....*....|....*....|....*..
gi 1958776745 1398 AETSELGLRLSAAEGRAQGLEVELARVEAQRRVAEAQ 1434
Cdd:TIGR00606 1061 ENIDLIKRNHVLALGRQKGYEKEIKHFKKELREPQFR 1097
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 944-1292 3.50e-06

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 52.05  E-value: 3.50e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  944 ETLTGELAGLRQQVTATEEKAALDKELMTQKLVQAERETQASLREQRAAHEEDLQRLQREKEAawrelQAERAQLQGQLQ 1023
Cdd:pfam17380  269 EFLNQLLHIVQHQKAVSERQQQEKFEKMEQERLRQEKEEKAREVERRRKLEEAEKARQAEMDR-----QAAIYAEQERMA 343

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1024 QEREELLARMEaekeelseeiaalQQERDEGLllaESEKQQALSLKESEKTALSEklmgtrhslaaisLEMERQKRDAQS 1103
Cdd:pfam17380  344 MERERELERIR-------------QEERKREL---ERIRQEEIAMEISRMRELER-------------LQMERQQKNERV 394

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1104 RQEQDRNTVNALTSE--LRDLRAQLEEATAAHAQQVKELQEQTGNLGRQREACMR----EAEELRTQLRLLEDTRDGLRR 1177
Cdd:pfam17380  395 RQELEAARKVKILEEerQRKIQQQKVEMEQIRAEQEEARQREVRRLEEERAREMErvrlEEQERQQQVERLRQQEEERKR 474

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1178 ELLEAQRKVRDSQDSSEAHR----QEASELRRSLSEGTKEREALRRSNEELRTAVKKAESERISLKLANEDKEQKLALLE 1253
Cdd:pfam17380  475 KKLELEKEKRDRKRAEEQRRkileKELEERKQAMIEEERKRKLLEKEMEERQKAIYEEERRREAEEERRKQQEMEERRRI 554

                          330       340       350
                   ....*....|....*....|....*....|....*....
gi 1958776745 1254 EARMSVAKEagelraslqevERSRLEARRELQELRRQMK 1292
Cdd:pfam17380  555 QEQMRKATE-----------ERSRLEAMEREREMMRQIV 582
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
78-259 4.23e-06

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 51.94  E-value: 4.23e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745   78 LLSLQEENQLLQQELSRVEDLLAQSRAERDELAIKYNAINERLEQAVRLETGELEAQEPRGLVRQSVELRRQLQEEQASY 157
Cdd:COG3206    207 LVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDALPELLQSPVIQQLRAQLAELEAELAELSARY 286

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  158 RRKLQAYQEGQQRQAQLVQRLQAKILQYKKQCSEMEKQLLERSTELEQQRLRDTEHSQDLDRALLRLEEEQQRSASLAQV 237
Cdd:COG3206    287 TPNHPDVIALRAQIAALRAQLQQEAQRILASLEAELEALQAREASLQAQLAQLEARLAELPELEAELRRLEREVEVAREL 366

                          170       180
                   ....*....|....*....|..
gi 1958776745  238 NDMLREQLDQANLANQTLSEDI 259
Cdd:COG3206    367 YESLLQRLEEARLAEALTVGNV 388
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 73-480 4.43e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 51.86  E-value: 4.43e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745   73 PEMASLLSLQEENQLLQQELSRVEDLLAQSRAERDELAIKYNAINERLEQAVRLETGELEAQEprglvrQSVELRRQLQE 152
Cdd:COG1196    306 RLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALL------EAEAELAEAEE 379

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  153 EQASYRRKLQAYQEGQQRQAQLVQRLQAKILQYKKQCSEMEKQLLERSTELEQQRLRDTEHSQDLDRALLRLEEEQQRSA 232
Cdd:COG1196    380 ELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEE 459

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  233 SLAQVNDMLREQLDQANLANQTLSEDICKVTSdwtrscKELEQREATWRREEESFNAYFSSEHSRLLLLWRQVMGLRRMA 312
Cdd:COG1196    460 ALLELLAELLEEAALLEAALAELLEELAEAAA------RLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVE 533

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  313 SEVKMGTERDLLQLGGELVRTSRavqEVGLGLSASLQRAESRAEAALEKQKLLQAQLEEQLRAKLLREKDLAQLQVQSDL 392
Cdd:COG1196    534 AAYEAALEAALAAALQNIVVEDD---EVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLRE 610

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  393 DKADLSARVTELALSVEHLQNQNTEKDQVNRTLSDKLEALESLRLQEQTTLDTEDGEGLQQTLRDLAQAALSDTESGVQL 472
Cdd:COG1196    611 ADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAE 690


                   ....*...
gi 1958776745  473 SNSERTAD 480
Cdd:COG1196    691 EELELEEA 698
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
663-1053 4.66e-06

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 51.69  E-value: 4.66e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  663 LERSHRQLEQLEVKRSGLTKELVEVREALSCAVLQRDVLQTEKAEVAEALTKAEAGRAQLELSVTKLRAEEASLRDSLSK 742
Cdd:COG4717     48 LERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQL 127

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  743 MSALNEsLAQDKLELNRLIAQLEEEKAALLGRQQQAEHATSLAVEKQERLEQLRLEQEVERQGLEGSLCVAEQAREALGQ 822
Cdd:COG4717    128 LPLYQE-LEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQ 206

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  823 QILVLRSERSHLQEQVAQLSRQLNGRdqeldqalrESQRQVEALERAAREKEAMAKERAGLAVQLAAAEREGRTLSEET- 901
Cdd:COG4717    207 RLAELEEELEEAQEELEELEEELEQL---------ENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAg 277

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  902 -------------IRLRLEKEALESSLFDVQRQLAQLEARREQLEADSQALLLAKETLTGELAGLRQQVTATEEKAALDK 968
Cdd:COG4717    278 vlflvlgllallfLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAE 357

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  969 ELMTQKLVQAERETQASLREQRAAHEEDLQRLQREKEAAWRELQAERAQLQGQLQQEREELLARMEAEKEEL-SEEIAAL 1047
Cdd:COG4717    358 ELEEELQLEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEElEEELEEL 437


                   ....*.
gi 1958776745 1048 QQERDE 1053
Cdd:COG4717    438 EEELEE 443
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
682-1231 4.85e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 51.84  E-value: 4.85e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  682 KELVEVREALSCAVLQRDVLQtEKAEVAEALTKAEAGRAQLELSVTKLRAEEASLRDSLskmsalneslaqdkleLNRLI 761
Cdd:COG4913    235 DDLERAHEALEDAREQIELLE-PIRELAERYAAARERLAELEYLRAALRLWFAQRRLEL----------------LEAEL 297

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  762 AQLEEEKAALLGRQQQAEHATSLAVEKQERLEQLRLEQEVERqglegsLCVAEQAREALGQQILVLRSERSHLQEQVAQL 841
Cdd:COG4913    298 EELRAELARLEAELERLEARLDALREELDELEAQIRGNGGDR------LEQLEREIERLERELEERERRRARLEALLAAL 371

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  842 SRQLNGRDQELDQALRESQRQVEALERaarEKEAMAKERAGLAVQLAAAEREGRTLSEETIRLRLEKEALESSLFDVQRQ 921
Cdd:COG4913    372 GLPLPASAEEFAALRAEAAALLEALEE---ELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALRDA 448

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  922 LAQ-LEARREQL------------EAD----------SQALLLA--------------KETLTGELAGLR-QQVTATEEK 963
Cdd:COG4913    449 LAEaLGLDEAELpfvgelievrpeEERwrgaiervlgGFALTLLvppehyaaalrwvnRLHLRGRLVYERvRTGLPDPER 528

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  964 AALDKELMTQKLVQAERETQASLRE---QRAAHE--EDLQRLQREKEAAWRELQ----AERAQLQGQLQQEREELLARme 1034
Cdd:COG4913    529 PRLDPDSLAGKLDFKPHPFRAWLEAelgRRFDYVcvDSPEELRRHPRAITRAGQvkgnGTRHEKDDRRRIRSRYVLGF-- 606

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1035 aekeELSEEIAALQQERDEglllAESEKQQALSLKESEKTALseKLMGTRHSLAAISLEMERQKRDAQSRQEQDRNTVNA 1114
Cdd:COG4913    607 ----DNRAKLAALEAELAE----LEEELAEAEERLEALEAEL--DALQERREALQRLAEYSWDEIDVASAEREIAELEAE 676

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1115 LTS---------ELRDLRAQLEEATAAHAQQVKELQEQTGNLGRQREACMREAEELRTQLRLLEDTRDGLRRELLEAQrk 1185
Cdd:COG4913    677 LERldassddlaALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEER-- 754

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*.
gi 1958776745 1186 vRDSQDSSEAHRQEASELRRSLSEGTKEREALRRSNEELRTAVKKA 1231
Cdd:COG4913    755 -FAAALGDAVERELRENLEERIDALRARLNRAEEELERAMRAFNRE 799
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
899-1317 5.48e-06

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 51.31  E-value: 5.48e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  899 EETIRLRLEKEALESSLFDVQRQLAQLEARREQLEADSQALLLAKETLTGELAGLRQQVTATEEKAALDKELMTQKLVQA 978
Cdd:COG4717     74 KELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAELAELPERLEELEE 153

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  979 ERETQASLREQRAAHEEDLQRLQREKEAAWRELQAERAQLQGQLQQEREELLARMEAEKEELSEEIAALQQERDEgLLLA 1058
Cdd:COG4717    154 RLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEE-LEQL 232

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1059 ESEKQQALSLKESEKTALSEKLMGTRHSLAAISLEMERQkrdaqsrqeqdRNTVNALTSELRDLRAQLEEATAAHAQQVK 1138
Cdd:COG4717    233 ENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSL-----------ILTIAGVLFLVLGLLALLFLLLAREKASLG 301

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1139 ELQEQTGNLGRQREACMREAEELRTQLRLLEDTRDGLRRELLEAQRKVRDSQDSSEAHRQEA--SELRRSLSE-----GT 1211
Cdd:COG4717    302 KEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELqlEELEQEIAAllaeaGV 381

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1212 KEREALRRSNEELRTAVK-KAESERISLKLANEDKEQKLALLEEARMSVAKEAGELRASLQEVERSRLEARRELQELRRQ 1290
Cdd:COG4717    382 EDEEELRAALEQAEEYQElKEELEELEEQLEELLGELEELLEALDEEELEEELEELEEELEELEEELEELREELAELEAE 461

                          410       420
                   ....*....|....*....|....*....
gi 1958776745 1291 MKTLDSDN--GRLGRELADLQSRLALGER 1317
Cdd:COG4717    462 LEQLEEDGelAELLQELEELKAELRELAE 490
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
834-1382 6.36e-06

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 51.60  E-value: 6.36e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  834 LQEQVAQLSRQ---LNGRDQELDQALRESQRQVEALERAAREKEAMAKEraglAVQLAAAEREGRTLSEETIRLRLEKEA 910
Cdd:PRK03918   236 LKEEIEELEKElesLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKE----LKELKEKAEEYIKLSEFYEEYLDELRE 311

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  911 LESSLFDVQRQLAQLEARREQLEADSQALllakETLTGELAGLRQQVTATEEKAALDKELMtQKLVQAERETQASLREQR 990
Cdd:PRK03918   312 IEKRLSRLEEEINGIEERIKELEEKEERL----EELKKKLKELEKRLEELEERHELYEEAK-AKKEELERLKKRLTGLTP 386

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  991 AAHEEDLQRLQREKEAAWRELQAERAQLqGQLQQEREELLARMEAEKEELSE--EIAALQQERDEGLLLAESEKQQALSL 1068
Cdd:PRK03918   387 EKLEKELEELEKAKEEIEEEISKITARI-GELKKEIKELKKAIEELKKAKGKcpVCGRELTEEHRKELLEEYTAELKRIE 465

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1069 KESEKTALSEKLMGTRhslaAISLEMERQKRDAQSRQEQDRNTVNALTSELRDLRAQLEEATAAHAQQVKELQEQTGNLG 1148
Cdd:PRK03918   466 KELKEIEEKERKLRKE----LRELEKVLKKESELIKLKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEI 541

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1149 RQREACMREAEELRTQLRLLEDTRDGLRRELLEAQRKVRDSQDSSEahrqeaselrRSLSEGTKEREALRRSNEELRTAV 1228
Cdd:PRK03918   542 KSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESV----------EELEERLKELEPFYNEYLELKDAE 611

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1229 KKAESERISLKLANEDKEQKLALLEEarmsVAKEAGELRASLQEVERSRLEarRELQELRRQMKtldsdngRLGRELADL 1308
Cdd:PRK03918   612 KELEREEKELKKLEEELDKAFEELAE----TEKRLEELRKELEELEKKYSE--EEYEELREEYL-------ELSRELAGL 678

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1958776745 1309 QSRLAlgertEKESRREVLglrqkvlkgESSLEALKQELQGSQRKLQEQEAEFRARERgllgsLEEARGAEKKL 1382
Cdd:PRK03918   679 RAELE-----ELEKRREEI---------KKTLEKLKEELEEREKAKKELEKLEKALER-----VEELREKVKKY 733
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1279-1860 1.05e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 50.68  E-value: 1.05e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1279 EARRELQELRRQMKTLdSDNGRLGRELADLQSRLALGERTEKESRREVLGLRQKVLKGE-SSLEALKQELQGSQRKLQEQ 1357
Cdd:COG4913    239 RAHEALEDAREQIELL-EPIRELAERYAAARERLAELEYLRAALRLWFAQRRLELLEAElEELRAELARLEAELERLEAR 317

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1358 EAEFRARERGLLGSLEEARGAekklldsarslelRLEGVRAETSELGLRLSAAEGRAQGLEVELARVEAQRRVAEAQLGG 1437
Cdd:COG4913    318 LDALREELDELEAQIRGNGGD-------------RLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAA 384

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1438 LRSALRRGLGLGRVSSSPAREAPAggsgdglsspspleysprsqppspgpvaspappdldpeAVRDALRDFLQELRSAQR 1517
Cdd:COG4913    385 LRAEAAALLEALEEELEALEEALA--------------------------------------EAEAALRDLRRELRELEA 426

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1518 ERDELRVQTSTLSQQLAEMEAE-RDHAASRAKQLQKA-----VAESEEAWRSADRRLSGAQAELALQEEsvrrsRRECRA 1591
Cdd:COG4913    427 EIASLERRKSNIPARLLALRDAlAEALGLDEAELPFVgelieVRPEEERWRGAIERVLGGFALTLLVPP-----EHYAAA 501

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1592 TldqmavleRSLQATESELRASQEKVNKMKATEVKLESDKRRLKEVLDASES---RSIKLELQRRAL------EGELQR- 1661
Cdd:COG4913    502 L--------RWVNRLHLRGRLVYERVRTGLPDPERPRLDPDSLAGKLDFKPHpfrAWLEAELGRRFDyvcvdsPEELRRh 573

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1662 ----SRLGLGDREAHAQALQDRVDSLQRQV--ADSEVKAGTLQLTVERLSGALAKVEESEGTLRSKVQSLTD--ALAQSS 1733
Cdd:COG4913    574 praiTRAGQVKGNGTRHEKDDRRRIRSRYVlgFDNRAKLAALEAELAELEEELAEAEERLEALEAELDALQErrEALQRL 653

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1734 ASLTSSQDKNLYLQKALSTCEHDRQ----------VLQERLDAARQALSEARRQSSSLGEQVQTLRGELANLELQRGDAE 1803
Cdd:COG4913    654 AEYSWDEIDVASAEREIAELEAELErldassddlaALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQ 733

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1958776745 1804 GQLQQLQQVLRQRQEGEAVALRSVQKLQEERRLLQERL-GSLQRALAQLEAEKRELER 1860
Cdd:COG4913    734 DRLEAAEDLARLELRALLEERFAAALGDAVERELRENLeERIDALRARLNRAEEELER 791
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1093-1444 1.08e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 50.83  E-value: 1.08e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1093 EMERQKRDAQSRQEQDRNTVNALTSELRDLRAQLEEATAaHAQQVKELQEQTGNLGRQREACMREAEELRTQLRLLEDTR 1172
Cdd:PRK03918   190 NIEELIKEKEKELEEVLREINEISSELPELREELEKLEK-EVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERI 268

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1173 DGLRRELLEAQRKVRDS---------------------QDSSEAHRQEA--SELRRSLSEGTKEREALRRSNEELRTAVK 1229
Cdd:PRK03918   269 EELKKEIEELEEKVKELkelkekaeeyiklsefyeeylDELREIEKRLSrlEEEINGIEERIKELEEKEERLEELKKKLK 348

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1230 KAESERISLKLANEDKEQKLALLEEARMSVAKEAG----ELRASLQEVERSRLEARRELQELRRQMKTLDSDNGRLGREL 1305
Cdd:PRK03918   349 ELEKRLEELEERHELYEEAKAKKEELERLKKRLTGltpeKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAI 428

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1306 ADLQS--------RLALGERTEKESRREVLGLRQKVLKGESSLEALKQELQGSQRKLqEQEAEFRARERGLLGSLEEARG 1377
Cdd:PRK03918   429 EELKKakgkcpvcGRELTEEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELREL-EKVLKKESELIKLKELAEQLKE 507

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1958776745 1378 AEKKL----LDSARSLELRLEGVRAETSELGLRLSAAEG---RAQGLEVELARVEAQRRVAEAQLGGLRSALRR 1444
Cdd:PRK03918   508 LEEKLkkynLEELEKKAEEYEKLKEKLIKLKGEIKSLKKeleKLEELKKKLAELEKKLDELEEELAELLKELEE 581
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 555-1256 1.09e-05

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 50.74  E-value: 1.09e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  555 RKQLSDSEGERRGLEEQLQRLRDQTATSVQAQEDAQREAQRLRSANEILSREKGNLSHSLQVAQQQAEDLRQELEKLQAA 634
Cdd:pfam02463  201 KLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKE 280

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  635 QEELRRQHTQLEDQQEDTVQEGARARRELERSHRQLEQLEVKRSGLTKELVEVREalscavlQRDVLQTEKAEVAEALTK 714
Cdd:pfam02463  281 KKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKE-------EIEELEKELKELEIKREA 353

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  715 AEAGRAQLELSVTKLRAEEASLRDSLSKMSALNESLAQDKLELNRLIAQLEEEKAALLGRQQQAEHATSLA-------VE 787
Cdd:pfam02463  354 EEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEkkeeleiLE 433

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  788 KQERLEQLRLEQEVERQGLEGSLCVAEQAREALGQQILVLRSERSHLQEQVAQLSRQLNGRDQELDQALRESQRQVEALE 867
Cdd:pfam02463  434 EEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLL 513

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  868 RAAREKE-------AMAKERAGLAVQLAAAEREGRTLSEETIRLRLEKEALESSLFDVQRQL----AQLEARREQLEADS 936
Cdd:pfam02463  514 ALIKDGVggriisaHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLgarkLRLLIPKLKLPLKS 593

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  937 QALLLAKETLTGELAGLRQQVTATEEKAALDKELMTQKLVQAERETQASLREQRAAH-EEDLQRLQREKEAAWRELQAER 1015
Cdd:pfam02463  594 IAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKgVSLEEGLAEKSEVKASLSELTK 673

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1016 AQLQGQLQQEREELLARMEAEKEELSEEIAALQQERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLAAISLEME 1095
Cdd:pfam02463  674 ELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEE 753

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1096 RQKRDaqsrQEQDRNTVNALTSELRDLRAQLEEATAAHAQQVKELQEQTGNLGRQREACMREAEELRTQLRLLEDTRDGL 1175
Cdd:pfam02463  754 KSRLK----KEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEK 829

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1176 RRELLEAQRKVRDSQDSSEAhrQEASELRRSLSEGTKEREALRRSNEELRTAVKKAESERISLKLANEDKEQKLALLEEA 1255
Cdd:pfam02463  830 IKEEELEELALELKEEQKLE--KLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQ 907


                   .
gi 1958776745 1256 R 1256
Cdd:pfam02463  908 K 908
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 545-752 1.38e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 49.76  E-value: 1.38e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  545 EASQDLLGSVRKQLSDSEGERRGLEEQLQRLRDQTATSVQAQEDAQREAQRLRSANEILSREKGNLSHSLQVAQQQAEDL 624
Cdd:COG4942     23 AEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQ 102

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  625 RQELEK-LQAAQEELRRQHTQLEDQQEDTVQEGARA----------RRELERSHRQLEQLEVKRSGLTKELVEVREALSC 693
Cdd:COG4942    103 KEELAElLRALYRLGRQPPLALLLSPEDFLDAVRRLqylkylaparREQAEELRADLAELAALRAELEAERAELEALLAE 182

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1958776745  694 AVLQRDVLQTEKAEVAEALTKAEAGRAQLELSVTKLRAEEASLRDSLSKMSALNESLAQ 752
Cdd:COG4942    183 LEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAE 241
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1549-1985 1.46e-05

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 50.42  E-value: 1.46e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1549 QLQKAVAESEEAwrSADRRLSGAQAELALQEESVRR---SRRECRATLDQMAVLERSLQATESELRASQEKVNKMKATEV 1625
Cdd:PRK02224   191 QLKAQIEEKEEK--DLHERLNGLESELAELDEEIERyeeQREQARETRDEADEVLEEHEERREELETLEAEIEDLRETIA 268

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1626 KLESDKRRLKEVLDASESRSIKLELQRRALEGELQRSRLGLGDREAHAQALQDRVDSLQRQVADSEVKAGTLQLTVERLS 1705
Cdd:PRK02224   269 ETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLR 348

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1706 GALAKVEESEGTLRSKVQSLTDALAQSSASLTSSQDKNLYLQKALSTCEH-------DRQVLQERLDAARQALSEARRQS 1778
Cdd:PRK02224   349 EDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRErfgdapvDLGNAEDFLEELREERDELRERE 428

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1779 SSLGEQVQTLRGELAnlELQRGDAEGQLQQLQQVLRQRQEGEAVALRSVQ--KLQEERRLLQERLGSLQRALAQLEAEK- 1855
Cdd:PRK02224   429 AELEATLRTARERVE--EAEALLEAGKCPECGQPVEGSPHVETIEEDRERveELEAELEDLEEEVEEVEERLERAEDLVe 506

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1856 --RELERSALQLD--KDRVALRKTLDKVEREKLRS-HEDTLRLNAERGRLDRTLTGAELDLAEAQQQIQHLEAQVVEVLE 1930
Cdd:PRK02224   507 aeDRIERLEERREdlEELIAERRETIEEKRERAEElRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKE 586

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1958776745 1931 RNHSPVQVEADEQHLE-LQQEVERLRSA-QVRTERTLEARER--AHRQRVSGLEEQVQG 1985
Cdd:PRK02224   587 RIESLERIRTLLAAIAdAEDEIERLREKrEALAELNDERRERlaEKRERKRELEAEFDE 645
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1543-1782 1.51e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 49.38  E-value: 1.51e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1543 AASRAKQLQKAVAESEEAWRSADRRLSGAQAELALQEESVRRSRRECRATLDQMAVLERSLQATESELRASQEKVNKMKA 1622
Cdd:COG4942     11 LALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEK 90

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1623 TEVKLESDKRRLKEVLDASESRSIKLELQRRALEGELQRSRLGLGDR----EAHAQALQDRVDSLQRQVADSEVKAGTLQ 1698
Cdd:COG4942     91 EIAELRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRlqylKYLAPARREQAEELRADLAELAALRAELE 170

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1699 LTVERLSGALAKVEESEGTLRSKVQSLTDALAQSSASLTSSQDKNLYLQKalstcehDRQVLQERLDAARQALSEARRQS 1778
Cdd:COG4942    171 AERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQ-------EAEELEALIARLEAEAAAAAERT 243


                   ....
gi 1958776745 1779 SSLG 1782
Cdd:COG4942    244 PAAG 247
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 822-1108 1.63e-05

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 50.12  E-value: 1.63e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  822 QQILVLRSERSHLQEQVAQLSRQLNGRDQ-ELDQALRESQRQVEALERAAREKEAMAKERAGLAVQLAAAEREGRTLSEE 900
Cdd:pfam17380  289 QQEKFEKMEQERLRQEKEEKAREVERRRKlEEAEKARQAEMDRQAAIYAEQERMAMERERELERIRQEERKRELERIRQE 368

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  901 TIRLRLEKealesslfdvQRQLAQLEARREQleadsqalllAKETLTGELAGLRQQVTATEEKaaldkelmTQKLVQAER 980
Cdd:pfam17380  369 EIAMEISR----------MRELERLQMERQQ----------KNERVRQELEAARKVKILEEER--------QRKIQQQKV 420

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  981 ETQASLREQRAAHEEDLQRLQREKEAAWRELQAERAQLQGQLQQERE-ELLARMEAEKEELSEEIAALQQERDEGLLLAE 1059
Cdd:pfam17380  421 EMEQIRAEQEEARQREVRRLEEERAREMERVRLEEQERQQQVERLRQqEEERKRKKLELEKEKRDRKRAEEQRRKILEKE 500

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*....
gi 1958776745 1060 SEKQQALSLKESEKTALSEKLMGTRHSlaAISLEMERQKRDAQSRQEQD 1108
Cdd:pfam17380  501 LEERKQAMIEEERKRKLLEKEMEERQK--AIYEEERRREAEEERRKQQE 547
mukB PRK04863
chromosome partition protein MukB;
525-1240 1.73e-05

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 50.34  E-value: 1.73e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  525 LIHSALHKRQlQVQDMRGRYEASQDLLGSVRKQLSDSEGERRGLEEQLQRLRDQTAtSVQAQEDAQREAQRLRSANEILS 604
Cdd:PRK04863   284 HLEEALELRR-ELYTSRRQLAAEQYRLVEMARELAELNEAESDLEQDYQAASDHLN-LVQTALRQQEKIERYQADLEELE 361

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  605 REkgnLSHSLQVAQQQAEDLRQELEKLQAAQEELRRQHTQLEDQQE-------------DTVQEGARARRELERSHRQLE 671
Cdd:PRK04863   362 ER---LEEQNEVVEEADEQQEENEARAEAAEEEVDELKSQLADYQQaldvqqtraiqyqQAVQALERAKQLCGLPDLTAD 438

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  672 QLEVKRSGLTKELVEVREALSCAVLQRDVLQTEKAEVAEALTKAEAGRAQLELSVTKLRAEEASLRdsLSKMSALNESLA 751
Cdd:PRK04863   439 NAEDWLEEFQAKEQEATEELLSLEQKLSVAQAAHSQFEQAYQLVRKIAGEVSRSEAWDVARELLRR--LREQRHLAEQLQ 516

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  752 QDKLELNRLIAQLEEEKAALlGRQQQAEHATSLAVEKQERLEQLRLEQEVERQGLEGSLCVAEQAREALGQQILVLRSER 831
Cdd:PRK04863   517 QLRMRLSELEQRLRQQQRAE-RLLAEFCKRLGKNLDDEDELEQLQEELEARLESLSESVSEARERRMALRQQLEQLQARI 595

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  832 SHL----------QEQVAQLSRQLnGRDQELDQALRESQRQVEALERAAREkeamakERAGLAVQLAAAEREGRTLS--- 898
Cdd:PRK04863   596 QRLaarapawlaaQDALARLREQS-GEEFEDSQDVTEYMQQLLERERELTV------ERDELAARKQALDEEIERLSqpg 668

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  899 -EETIRLRLEKE----ALESSLFD----------------------------VQRQLAQLEARREQL---EADSQAL--- 939
Cdd:PRK04863   669 gSEDPRLNALAErfggVLLSEIYDdvsledapyfsalygparhaivvpdlsdAAEQLAGLEDCPEDLyliEGDPDSFdds 748

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  940 -----LLAKEtLTGELAGLRQQVTATEE-----KAALDKELmtqKLVQAERETQASLREQRAAHEEDLQRL--------- 1000
Cdd:PRK04863   749 vfsveELEKA-VVVKIADRQWRYSRFPEvplfgRAAREKRI---EQLRAEREELAERYATLSFDVQKLQRLhqafsrfig 824

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1001 -------QREKEAAWRELQAERAQLQGQLQQEREELLaRMEAEKEELSEEIAALQQERDE-GLLLAESEKQQALSLKESE 1072
Cdd:PRK04863   825 shlavafEADPEAELRQLNRRRVELERALADHESQEQ-QQRSQLEQAKEGLSALNRLLPRlNLLADETLADRVEEIREQL 903

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1073 KTALSEKLMGTRHSLAAISLE---------------MERQKRDAQSRQEQDRNTVNALTS-------------------- 1117
Cdd:PRK04863   904 DEAEEAKRFVQQHGNALAQLEpivsvlqsdpeqfeqLKQDYQQAQQTQRDAKQQAFALTEvvqrrahfsyedaaemlakn 983

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1118 -----------------------ELRDLRAQLEEATAAHA----------QQVKELQEQTGNLG---------------- 1148
Cdd:PRK04863   984 sdlneklrqrleqaeqertrareQLRQAQAQLAQYNQVLAslkssydakrQMLQELKQELQDLGvpadsgaeerararrd 1063

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1149 -----------------RQREACMREAEELRTQLRLLEDTRDGLRRELLEAQ-------RKVRDSQDSSEAHRQEASELr 1204
Cdd:PRK04863  1064 elharlsanrsrrnqleKQLTFCEAEMDNLTKKLRKLERDYHEMREQVVNAKagwcavlRLVKDNGVERRLHRRELAYL- 1142

                          890       900       910
                   ....*....|....*....|....*....|....*.
gi 1958776745 1205 rslsEGTKEREALRRSNEELRTAVKKAESERISLKL 1240
Cdd:PRK04863  1143 ----SADELRSMSDKALGALRLAVADNEHLRDVLRL 1174
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1510-1739 2.16e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.99  E-value: 2.16e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1510 QELRSAQRERDELRVQTSTLSQQLAEMEAERDHAASRAKQLQKAVAESEEAWRSADRRLSGAQAELA---LQEESVRRSR 1586
Cdd:COG4942     20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAeleKEIAELRAEL 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1587 RECRATL-DQMAVLERSLQATESELRASQEKVNKMKATEVKLESDKRRLKEVLDASESRSIKLELQRRALEGELQRsrlg 1665
Cdd:COG4942    100 EAQKEELaELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAE---- 175

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1958776745 1666 lgdREAHAQALQDRVDSLQRQVADSEVKAGTLQLTVERLSGALAKVEESEGTLRSKVQSLTDALAQSSASLTSS 1739
Cdd:COG4942    176 ---LEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAA 246
mukB PRK04863
chromosome partition protein MukB;
791-1208 2.21e-05

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 49.96  E-value: 2.21e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  791 RLEQLRLEQEVERQGLEGSLCVAEQAREALGQQILVLRSERSHLQEQVAQLSRQLNgrdqeldqALRESQRQVEALERAA 870
Cdd:PRK04863   283 VHLEEALELRRELYTSRRQLAAEQYRLVEMARELAELNEAESDLEQDYQAASDHLN--------LVQTALRQQEKIERYQ 354

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  871 REKEAM--AKERAGLAVQLAAAEREGRtlSEETIRLRLEKEALESSLFDVQRQLAQLEARREQLEADSQAL-----LLAK 943
Cdd:PRK04863   355 ADLEELeeRLEEQNEVVEEADEQQEEN--EARAEAAEEEVDELKSQLADYQQALDVQQTRAIQYQQAVQALerakqLCGL 432

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  944 ETLTGELAGLRQQVTATEEKAALDKELMT-QKLVQAE----RETQASLREQRAAHE---EDLQRLQREKEAAWRELQAER 1015
Cdd:PRK04863   433 PDLTADNAEDWLEEFQAKEQEATEELLSLeQKLSVAQaahsQFEQAYQLVRKIAGEvsrSEAWDVARELLRRLREQRHLA 512

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1016 AQLQgQLQQEREELLARmeaekeelseeiaaLQQERDEGLLLAESEKQQALSL-KESEKTALSEKLMGTRHSLaaislem 1094
Cdd:PRK04863   513 EQLQ-QLRMRLSELEQR--------------LRQQQRAERLLAEFCKRLGKNLdDEDELEQLQEELEARLESL------- 570

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1095 ERQKRDAQSRQEQDRNTVNALTSELRDLRAQLEEATAAHAQqVKELQEQTGNLGRQREACMreaeelrtqlrlledtrdG 1174
Cdd:PRK04863   571 SESVSEARERRMALRQQLEQLQARIQRLAARAPAWLAAQDA-LARLREQSGEEFEDSQDVT------------------E 631

                          410       420       430
                   ....*....|....*....|....*....|....
gi 1958776745 1175 LRRELLEAQRKVRDSQDSSEAHRQEASELRRSLS 1208
Cdd:PRK04863   632 YMQQLLERERELTVERDELAARKQALDEEIERLS 665
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1565-1799 2.60e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 49.53  E-value: 2.60e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1565 DRRLSGAQAELALQE-ESVRRSRRECRATLDQMAVLERslqateseLRASQEKVNKMKATEVKLESDKRRLKevLDASES 1643
Cdd:COG4913    219 EEPDTFEAADALVEHfDDLERAHEALEDAREQIELLEP--------IRELAERYAAARERLAELEYLRAALR--LWFAQR 288

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1644 RSIKLELQRRALEGELQRSRLGLGDREAHAQALQDRVDSLQRQVADSEVKAgtlqltVERLSGALAKVEESEGTLRSKVQ 1723
Cdd:COG4913    289 RLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGGDR------LEQLEREIERLERELEERERRRA 362

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958776745 1724 SLTDALAQSSASLTSSQDKnlyLQKALSTCEHDRQVLQERLDAARQALSEARRQSSSLGEQVQTLRGELANLELQR 1799
Cdd:COG4913    363 RLEALLAALGLPLPASAEE---FAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRK 435
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
617-1235 2.97e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 49.29  E-value: 2.97e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  617 AQQQAEDLRQELEKLQAAQEELRRQHTQLEDQQEDTVQEGARARRELERSHRQLEQLEVKRSGLTKELVEV---REALSC 693
Cdd:PRK03918   163 AYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELeelKEEIEE 242

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  694 AVLQRDVLQTEKAEVAEALTKAEAGRAQLELSVTKLRAEEASLRdSLSKMSALNESLAQDKLELNRLIAQLEEEKAALLG 773
Cdd:PRK03918   243 LEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELK-ELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEE 321

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  774 RQQQAEHATSLAVEKQERLEQLRLEQEverqGLEGSLCVAEQAREALgQQILVLRSERSHLQEQVAQLS-RQLNGRDQEL 852
Cdd:PRK03918   322 EINGIEERIKELEEKEERLEELKKKLK----ELEKRLEELEERHELY-EEAKAKKEELERLKKRLTGLTpEKLEKELEEL 396

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  853 DQALRESQRQVEALERAAREKEAMAKERAGLAVQLAAAERE----GRTLSEETIRLRLEKEALEssLFDVQRQLAQLEAR 928
Cdd:PRK03918   397 EKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKcpvcGRELTEEHRKELLEEYTAE--LKRIEKELKEIEEK 474

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  929 REQLEADSQAL--LLAKETLTGELAGLRQQVTATEEKAaldKELMTQKLVQAERETQaSLREQRAAHEEDLQRLQREKEA 1006
Cdd:PRK03918   475 ERKLRKELRELekVLKKESELIKLKELAEQLKELEEKL---KKYNLEELEKKAEEYE-KLKEKLIKLKGEIKSLKKELEK 550

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1007 AwRELQAERAQLQ---GQLQQEREELLARMEAEKEELSEEIAALQQERDE------GLLLAESEKQQALSLKESEKTALS 1077
Cdd:PRK03918   551 L-EELKKKLAELEkklDELEEELAELLKELEELGFESVEELEERLKELEPfyneylELKDAEKELEREEKELKKLEEELD 629

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1078 ---EKLMGTRHSLAAISLEMER-QKRDAQSRQEQDRNTVNALTSELRDLRAQLEEATaAHAQQVKELQEQTGNLGRQREA 1153
Cdd:PRK03918   630 kafEELAETEKRLEELRKELEElEKKYSEEEYEELREEYLELSRELAGLRAELEELE-KRREEIKKTLEKLKEELEEREK 708

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1154 CMREAEELRTQLRLLEDTRDGLRRelLEAQRKVRDSQDSSEAhrqeASELRRSLSEGTKEREALRRSNEELRTAVKKAES 1233
Cdd:PRK03918   709 AKKELEKLEKALERVEELREKVKK--YKALLKERALSKVGEI----ASEIFEELTEGKYSGVRVKAEENKVKLFVVYQGK 782


                   ..
gi 1958776745 1234 ER 1235
Cdd:PRK03918   783 ER 784
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 968-1835 3.42e-05

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 49.20  E-value: 3.42e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  968 KELMTQKLVQAERETQASLREQRAAHEEDLQRLQREKEAAWR---------ELQAERAQLQGQLQQEREELLARMEAEKE 1038
Cdd:pfam02463  168 KRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKAleyyqlkekLELEEEYLLYLDYLKLNEERIDLLQELLR 247

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1039 ELSEEIAALQQERDeglllAESEKQQALSLKESEKTALSEKLMGTRHSLAAISLEMERQKRDAQSRQEQDRNTVNALTSE 1118
Cdd:pfam02463  248 DEQEEIESSKQEIE-----KEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKE 322

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1119 LRDLRAQLEEATAAHAQQVKELQEQTgnlgRQREACMREAEELRTQLRLLEDTRDGLRRELLEAQrkvRDSQDSSEAHRQ 1198
Cdd:pfam02463  323 KKKAEKELKKEKEEIEELEKELKELE----IKREAEEEEEEELEKLQEKLEQLEEELLAKKKLES---ERLSSAAKLKEE 395

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1199 EASELRRSLSEGTKEREALRRSNEELRTAVKKAESERISLKLANEDKEQKLALLEEARMSVAKEAGELRASLQEVERSRL 1278
Cdd:pfam02463  396 ELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLK 475

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1279 EARRELQELRRQmktldsdngrLGRELADLQSRLALGERTEKESRREVLGLRQKVLkgessleALKQELQGSQRKLQEQE 1358
Cdd:pfam02463  476 ETQLVKLQEQLE----------LLLSRQKLEERSQKESKARSGLKVLLALIKDGVG-------GRIISAHGRLGDLGVAV 538

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1359 AEFRARERGLLGSLEEARGAEKKLLDSARSLELRLEGVRAETSELGLRLSAAEGRAQGLEVELARVEAQRRVAEAQLGGL 1438
Cdd:pfam02463  539 ENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADED 618

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1439 RSALRRGLGLGRVSSSPAREAPAGGSGDGLSSPSPLEYSpRSQPPSPGPVASPAPPDLDPEAVRDALRDFLQELRSAQRE 1518
Cdd:pfam02463  619 DKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEG-LAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRR 697

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1519 RDELRVQTSTLSQQLAEMEAERDHAASRAKQLQKAVAESEEAWRSADRRLSGAQAELALQEESVRRSRRECRATLDQMAV 1598
Cdd:pfam02463  698 QLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELA 777

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1599 LERSLQATESELRASQEKVNKMKATEVKLESDKRRLKEVLDASESRSIKLELQRRALEGELQRSRLGLGDREAHAQALQD 1678
Cdd:pfam02463  778 EEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELE 857

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1679 RVDSLQRQVADSEVKAGTLQLT-----VERLSGALAKVEESEGTLRSKVQSLTDALAQSSASLTSSQDKNLYLQKALSTC 1753
Cdd:pfam02463  858 RLEEEITKEELLQELLLKEEELeeqklKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEP 937

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1754 EHDRQVLQERLDAARQALSEARRQSSSLGEQVQTLRGELANLELQRGDAEGQLQQLQQVLRQRQEGEAVALRSVQKLQEE 1833
Cdd:pfam02463  938 EELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQ 1017


                   ..
gi 1958776745 1834 RR 1835
Cdd:pfam02463 1018 RL 1019
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 1497-1974 3.57e-05

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 49.18  E-value: 3.57e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1497 DPEAVRDALRDFLQELRSAQRERDELRvQTSTLSQQLAEMEAERDhaASRAKQLQKAVAESEEAWRSADRRLSGAQAELA 1576
Cdd:COG3096    233 DMEAALRENRMTLEAIRVTQSDRDLFK-HLITEATNYVAADYMRH--ANERRELSERALELRRELFGARRQLAEEQYRLV 309

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1577 lqeesvrrsrrecrATLDQMAVLERSLQATESELRASQEKVNKMKATEVKLESDKRRLKEVLDASEsrsiKLELQRRALE 1656
Cdd:COG3096    310 --------------EMARELEELSARESDLEQDYQAASDHLNLVQTALRQQEKIERYQEDLEELTE----RLEEQEEVVE 371

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1657 gELQRSRLglgDREAHAQALQDRVDSLQRQVAD-------SEVKAGTLQLTVERLSGA----------LAKVEESEGTLR 1719
Cdd:COG3096    372 -EAAEQLA---EAEARLEAAEEEVDSLKSQLADyqqaldvQQTRAIQYQQAVQALEKAralcglpdltPENAEDYLAAFR 447

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1720 SKVQSLTDALAQSSASLTSSQDKNLYLQKALSTCEH--DRQVLQERLDAARQALSEARRQSSsLGEQVQTLRGELANLEl 1797
Cdd:COG3096    448 AKEQQATEEVLELEQKLSVADAARRQFEKAYELVCKiaGEVERSQAWQTARELLRRYRSQQA-LAQRLQQLRAQLAELE- 525

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1798 qrgdaegqlqqlqqvlrqrqegeavalRSVQKLQEERRLLQE---RLGS-------LQRALAQLEAEKRELERSALQLDK 1867
Cdd:COG3096    526 ---------------------------QRLRQQQNAERLLEEfcqRIGQqldaaeeLEELLAELEAQLEELEEQAAEAVE 578

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1868 DRVALRKTLDKVEREKlrshedtlrlnaergrldRTLTGAELDLAEAQQQIQHLEAQVVEVLErnhSPVQVEAdeqhlEL 1947
Cdd:COG3096    579 QRSELRQQLEQLRARI------------------KELAARAPAWLAAQDALERLREQSGEALA---DSQEVTA-----AM 632

                          490       500
                   ....*....|....*....|....*..
gi 1958776745 1948 QQEVERLRSAQVRTERTLEARERAHRQ 1974
Cdd:COG3096    633 QQLLEREREATVERDELAARKQALESQ 659
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 619-1411 3.89e-05

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 49.02  E-value: 3.89e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  619 QQAEDLRQELEKLQAAQE----------ELRRQHTQLEDQQeDTVQEGARARRELersHRQLEQLEVKRSGLTKELVEVR 688
Cdd:pfam01576    2 RQEEEMQAKEEELQKVKErqqkaeselkELEKKHQQLCEEK-NALQEQLQAETEL---CAEAEEMRARLAARKQELEEIL 77

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  689 EALSCAVLQRD----VLQTEKAEVAEALTKAEAGRAQLELSVTKLRAEEASLRDSLSKMSALNESLAQDKLELNRLIAQL 764
Cdd:pfam01576   78 HELESRLEEEEersqQLQNEKKKMQQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKLEEDILLLEDQNSKLSKERKLL 157

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  765 EEEKAALLGRQQQAEhatslavEKQERLEQLRLEQEVERQGLEGSLCVAEQAREALGQQILVLRSERSHLQEQVAQLSRQ 844
Cdd:pfam01576  158 EERISEFTSNLAEEE-------EKAKSLSKLKNKHEAMISDLEERLKKEEKGRQELEKAKRKLEGESTDLQEQIAELQAQ 230

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  845 LNGRDQELDQALRESQRQVEALERAAREKEAMAKERAGLAVQLA------AAEREGRTLSEETIR-LRLEKEALESSLFD 917
Cdd:pfam01576  231 IAELRAQLAKKEEELQAALARLEEETAQKNNALKKIRELEAQISelqedlESERAARNKAEKQRRdLGEELEALKTELED 310

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  918 VQRQLAQLEARREQLEADSQALllaKETLTGELAGLRQQVTATEEKAALDKELMTQKLVQAER------ETQASLREQRA 991
Cdd:pfam01576  311 TLDTTAAQQELRSKREQEVTEL---KKALEEETRSHEAQLQEMRQKHTQALEELTEQLEQAKRnkanleKAKQALESENA 387

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  992 AHEEDLQRLQREKEAAWRELQAERAQLQ------GQLQQEREELLARMEAEKEELSEEIAALQQERDEGLLLA------E 1059
Cdd:pfam01576  388 ELQAELRTLQQAKQDSEHKRKKLEGQLQelqarlSESERQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLSkdvsslE 467

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1060 SEKQQALSLKESE---KTALSEKLMGTRHSLAAIsleMERQKRDAQSRQEQDRNtVNALTSELRDLRAQLEEATAAhaqq 1136
Cdd:pfam01576  468 SQLQDTQELLQEEtrqKLNLSTRLRQLEDERNSL---QEQLEEEEEAKRNVERQ-LSTLQAQLSDMKKKLEEDAGT---- 539

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1137 VKELQEQTGNLGRQREACMREAEELRTQLRLLEDTRDGLRREL------LEAQRKV------------------------ 1186
Cdd:pfam01576  540 LEALEEGKKRLQRELEALTQQLEEKAAAYDKLEKTKNRLQQELddllvdLDHQRQLvsnlekkqkkfdqmlaeekaisar 619

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1187 -RDSQDSSEAHRQE----ASELRRSLSEGTKEREALRRSNEELRTAVKKAESERISLKLANEDKEQKLALLEEARMSVAK 1261
Cdd:pfam01576  620 yAEERDRAEAEAREketrALSLARALEEALEAKEELERTNKQLRAEMEDLVSSKDDVGKNVHELERSKRALEQQVEEMKT 699

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1262 EAGELRASLQEVERSRLEARRELQELR----RQMKTLDSDNGRLGRELADLQSRLALGERTEKESRREVLGLRQKVLKGE 1337
Cdd:pfam01576  700 QLEELEDELQATEDAKLRLEVNMQALKaqfeRDLQARDEQGEEKRRQLVKQVRELEAELEDERKQRAQAVAAKKKLELDL 779

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1958776745 1338 SSLEALKQELQGSQRKLQEQEAEFRARERGLLGSLEEARGAEKKLLDSARSLELRLEGVRAETSELGLRLSAAE 1411
Cdd:pfam01576  780 KELEAQIDAANKGREEAVKQLKKLQAQMKDLQRELEEARASRDEILAQSKESEKKLKNLEAELLQLQEDLAASE 853
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
528-876 3.96e-05

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 48.88  E-value: 3.96e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  528 SALHKRQLQVQDMRGRYEASQDLLGSVRKQLSDSEGERRGLEEQLQRLRDQTA---TSVQAQEDAQREAQRLRSANEI-- 602
Cdd:PRK02224   377 EAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAeleATLRTARERVEEAEALLEAGKCpe 456

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  603 --LSREKGNLSHSLQVAQQQAEDLRQELEKLQAAQEELRRQHTQLEDQQEdtvqegararrelerSHRQLEQLEVKRSGL 680
Cdd:PRK02224   457 cgQPVEGSPHVETIEEDRERVEELEAELEDLEEEVEEVEERLERAEDLVE---------------AEDRIERLEERREDL 521

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  681 TKELVEVREALSCAVLQRDVLQTEKAEVAEALTKAEAGRAQLELSVTKLRAEEASLRDSLSKMSALNESLAQdkleLNRL 760
Cdd:PRK02224   522 EELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLER----IRTL 597

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  761 IAQLEEEKAALLGRQQQAEHATSLAVEKQERLEQLR-----LEQEVERQGLEGSLCVAEQAREALGQ---QILVLRSERS 832
Cdd:PRK02224   598 LAAIADAEDEIERLREKREALAELNDERRERLAEKRerkreLEAEFDEARIEEAREDKERAEEYLEQveeKLDELREERD 677

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*.
gi 1958776745  833 HLQEQVAQLSRQLNGRD--QELDQALRESQRQVEALERAAREKEAM 876
Cdd:PRK02224   678 DLQAEIGAVENELEELEelRERREALENRVEALEALYDEAEELESM 723
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 895-1660 5.53e-05

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 48.58  E-value: 5.53e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  895 RTLSEETIRLRLEKEALESSLFDVQRQLAQLearreQLEADSQALLLAKETLTGELAGLRQQVTATEEKAA--LDKELMT 972
Cdd:pfam15921   92 RRLNESNELHEKQKFYLRQSVIDLQTKLQEM-----QMERDAMADIRRRESQSQEDLRNQLQNTVHELEAAkcLKEDMLE 166

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  973 QKLVQAERETQASLREQRAAHE-----EDLQRLQREK--------EAAWRELQAERAQLQGQLQQEREELLARMEAEKEE 1039
Cdd:pfam15921  167 DSNTQIEQLRKMMLSHEGVLQEirsilVDFEEASGKKiyehdsmsTMHFRSLGSAISKILRELDTEISYLKGRIFPVEDQ 246

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1040 LSEEIAALQQERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLAAISLEMERQKRDAQSRQEQDRNTVNALTSEL 1119
Cdd:pfam15921  247 LEALKSESQNKIELLLQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQARNQNSMYMRQLSDLESTV 326

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1120 RDLRAQLEEATAAHAQQVKELQEQ-------TGNLGRQREACMREAEELRTQLRLLEDTRDGLRRELLEAQRKVRDSQDS 1192
Cdd:pfam15921  327 SQLRSELREAKRMYEDKIEELEKQlvlanseLTEARTERDQFSQESGNLDDQLQKLLADLHKREKELSLEKEQNKRLWDR 406

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1193 SEAHRQEASELRRSLSEGTKEREALRRSNEELRTAVK-KAESERISLKLANEDKEQKLAL---LEEARMSVAKEAGELRA 1268
Cdd:pfam15921  407 DTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECQgQMERQMAAIQGKNESLEKVSSLtaqLESTKEMLRKVVEELTA 486

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1269 ---SLQEVERSRLEARRELQELRRQMKTLDSDNGRLgRELADLQSRLALGERTEKESRREVlglrqkvlkgESSLEALKQ 1345
Cdd:pfam15921  487 kkmTLESSERTVSDLTASLQEKERAIEATNAEITKL-RSRVDLKLQELQHLKNEGDHLRNV----------QTECEALKL 555

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1346 ELQGSQRKLQ--EQEAEFRARERGLLGSLEEARGAEKKLLDSA---RSLELRLEGVRAETSELGLRlsAAEGRAQGLEVE 1420
Cdd:pfam15921  556 QMAEKDKVIEilRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEindRRLELQEFKILKDKKDAKIR--ELEARVSDLELE 633

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1421 ---LARVEAQRRVAEAQLGGLRSALRRGLGLGRVSSSPAREapaggsgdglsSPSPLEYSPRSQppspgpvaspappdld 1497
Cdd:pfam15921  634 kvkLVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSE-----------DYEVLKRNFRNK---------------- 686

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1498 PEAVRDALRDFLQELRSAQRERDELRvqtstlsQQLAEMEAERDHAASRAKQLQKAVAESE---EAWRSADRRLSGAQAE 1574
Cdd:pfam15921  687 SEEMETTTNKLKMQLKSAQSELEQTR-------NTLKSMEGSDGHAMKVAMGMQKQITAKRgqiDALQSKIQFLEEAMTN 759

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1575 LALQEESVRRSRRECRATLDQMAVlERSLQATESELRASQEKVNKMKATEVKLESDKRRL-----KEVLDASESRSIKLE 1649
Cdd:pfam15921  760 ANKEKHFLKEEKNKLSQELSTVAT-EKNKMAGELEVLRSQERRLKEKVANMEVALDKASLqfaecQDIIQRQEQESVRLK 838

                          810
                   ....*....|.
gi 1958776745 1650 LQRRALEGELQ 1660
Cdd:pfam15921  839 LQHTLDVKELQ 849
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 521-1028 6.05e-05

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 48.43  E-value: 6.05e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  521 STLTLIHSALHKRQLQVQDMRGRYEASQDL--LGSVRKQLSDSEGERRGLEEQLQRLRDQTATSVQAQEDAQREAQRLRS 598
Cdd:TIGR00618  318 SKMRSRAKLLMKRAAHVKQQSSIEEQRRLLqtLHSQEIHIRDAHEVATSIREISCQQHTLTQHIHTLQQQKTTLTQKLQS 397

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  599 ANEILSREKgNLSHSLQVAQQQAEDLRQELEKLQAAQEELRRQHTQLEDQQEDTVQEGARARRELERSHRQLEQLEVKRS 678
Cdd:TIGR00618  398 LCKELDILQ-REQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQ 476

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  679 GLTKELVEVREALSCAVLQRDVLQTEKAEVAEALTKAEAGRAQLELSvtklRAEEASLRDSLSKMSALNESLAQDKLELN 758
Cdd:TIGR00618  477 TKEQIHLQETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQDIDNP----GPLTRRMQRGEQTYAQLETSEEDVYHQLT 552

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  759 RLIAQLEEEKAALLGRQQQAEHATSLAVEKQERLEQLRLEQEVERQGLEGSLcvaeqarEALGQQILVLRSERSHLQEQV 838
Cdd:TIGR00618  553 SERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLS-------EAEDMLACEQHALLRKLQPEQ 625

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  839 AQLSRQLNGRDQELDQALRESQRQVEALERAA-REKEAMAKERAGLAVQLAAAEREGRTLSEETIRLRLEKEALESSLFD 917
Cdd:TIGR00618  626 DLQDVRLHLQQCSQELALKLTALHALQLTLTQeRVREHALSIRVLPKELLASRQLALQKMQSEKEQLTYWKEMLAQCQTL 705

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  918 VQRQLAQLEARREQLEADSQALLLAKETLTGELAGLRQQVTATEEKAalDKELMTQKLVQAERETQASLREQRAAHEEDL 997
Cdd:TIGR00618  706 LRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQA--RTVLKARTEAHFNNNEEVTAALQTGAELSHL 783

                          490       500       510
                   ....*....|....*....|....*....|.
gi 1958776745  998 QRLQREKEAAWRELQAERAQLQGQLQQEREE 1028
Cdd:TIGR00618  784 AAEIQFFNRLREEDTHLLKTLEAEIGQEIPS 814
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
600-824 6.25e-05

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 48.09  E-value: 6.25e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  600 NEILSREKGNLSHSLQVAQQQAEDLRQELEKLQAAQEELRRQH--TQLEDQQEDTVQEGARARRELERSHRQLEQLEVKR 677
Cdd:COG3206    163 EQNLELRREEARKALEFLEEQLPELRKELEEAEAALEEFRQKNglVDLSEEAKLLLQQLSELESQLAEARAELAEAEARL 242

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  678 SGLTKELVEVREALScAVLQRDVLQTEKAEVAEALTKAEAGRAQLE---LSVTKLRAEEASLRdslskmSALNESLAQDK 754
Cdd:COG3206    243 AALRAQLGSGPDALP-ELLQSPVIQQLRAQLAELEAELAELSARYTpnhPDVIALRAQIAALR------AQLQQEAQRIL 315

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  755 LELNRLIAQLEEEKAALLGRQQQAEHATSLAVEKQERLEQLRLEQEVERQGLEGSLCVAEQAREALGQQI 824
Cdd:COG3206    316 ASLEAELEALQAREASLQAQLAQLEARLAELPELEAELRRLEREVEVARELYESLLQRLEEARLAEALTV 385
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 55-660 6.38e-05

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 48.19  E-value: 6.38e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745   55 EIITSNLSQPETPAPLQVPEMASLLSLQEE-----NQLLQQELSRVEDLLAQSRAERDELAIKYNAINERLEQAVRLETG 129
Cdd:pfam15921  277 EVEITGLTEKASSARSQANSIQSQLEIIQEqarnqNSMYMRQLSDLESTVSQLRSELREAKRMYEDKIEELEKQLVLANS 356

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  130 EL-EAQEPRGLVRQ-SVELRRQLQEEQASYRRKLQAYQEGQQRQAQLVQR----------LQAKILQYKKQCSEMEKQLL 197
Cdd:pfam15921  357 ELtEARTERDQFSQeSGNLDDQLQKLLADLHKREKELSLEKEQNKRLWDRdtgnsitidhLRRELDDRNMEVQRLEALLK 436

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  198 ERSTELEQQRLRDTEHSQDLDRALlrlEEEQQRSASLAQVNDMLREQLDQANLANQTLsEDICKVTSDWTRSCKELEqre 277
Cdd:pfam15921  437 AMKSECQGQMERQMAAIQGKNESL---EKVSSLTAQLESTKEMLRKVVEELTAKKMTL-ESSERTVSDLTASLQEKE--- 509

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  278 atwrREEESFNAYFSSEHSRLLLLWRQVMGLRRMASEVK-MGTERDLLQLggELVRTSRAVQEVGLGLSASLQRA--ESR 354
Cdd:pfam15921  510 ----RAIEATNAEITKLRSRVDLKLQELQHLKNEGDHLRnVQTECEALKL--QMAEKDKVIEILRQQIENMTQLVgqHGR 583

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  355 AEAALEKQKllqAQLEEQLRAKLLREKDLAQLQVQSDLDKADLSARVTELALSVEHLQNQNTEKDQVNRTLSDKLEALES 434
Cdd:pfam15921  584 TAGAMQVEK---AQLEKEINDRRLELQEFKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQLLN 660

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  435 LRLQEQTTLD--TEDGEGLQQTLRDLAQAALSDTES-GVQLSNSERTADTSDGSFRGLFGqrtptpprhsSPGRGRSPRR 511
Cdd:pfam15921  661 EVKTSRNELNslSEDYEVLKRNFRNKSEEMETTTNKlKMQLKSAQSELEQTRNTLKSMEG----------SDGHAMKVAM 730

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  512 GLspacsdsstltlihsalhkrQLQVQDMRGRYEASQDLLGSVRKQLSDSEGERRGLEEQLQRLRDQTATsvqaqedaqr 591
Cdd:pfam15921  731 GM--------------------QKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELST---------- 780

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1958776745  592 eaqrlrsaneiLSREKGNLSHSLQVAQQQAEDLRQELEKLQAAQEELRRQHTQLEDQQEDTVQEGARAR 660
Cdd:pfam15921  781 -----------VATEKNKMAGELEVLRSQERRLKEKVANMEVALDKASLQFAECQDIIQRQEQESVRLK 838
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 530-1323 7.08e-05

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 48.25  E-value: 7.08e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  530 LHKRQLQVQDMRGRYEASQDLLGSVRKQLSDSEGERRGLEEQLQRLRDQTATSVQAQEDAQREAQRLRSANEilsrekgN 609
Cdd:pfam01576  238 LAKKEEELQAALARLEEETAQKNNALKKIRELEAQISELQEDLESERAARNKAEKQRRDLGEELEALKTELE-------D 310

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  610 LSHSLQVAQQQAEDLRQELEKLQAAQEELRRQH-TQLEDQQEDTVQEGARARRELERSHRQLEQLEVKRSGLTKELVEVR 688
Cdd:pfam01576  311 TLDTTAAQQELRSKREQEVTELKKALEEETRSHeAQLQEMRQKHTQALEELTEQLEQAKRNKANLEKAKQALESENAELQ 390

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  689 EALScavlqrdVLQTEKAEVAEALTKAEAGRAQLELSVTKLRAEEASLRDSLSKMSALNESLAQDKLELNRLIAQLEEEK 768
Cdd:pfam01576  391 AELR-------TLQQAKQDSEHKRKKLEGQLQELQARLSESERQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDV 463

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  769 AALLGRQQQAEHATSLAVEKQERLEQLRLEQEVERQGLEGSLCVAEQAREALGQQILVLRSERSHLQEQVAQLSRQLNGR 848
Cdd:pfam01576  464 SSLESQLQDTQELLQEETRQKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEAL 543

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  849 DQELDQALRESQRQVEALERAAREKEAMAKERAGLAVQLAAAEREGRTLSEETIRLRLEKEALESSLFDVQRQLAQLEAR 928
Cdd:pfam01576  544 EEGKKRLQRELEALTQQLEEKAAAYDKLEKTKNRLQQELDDLLVDLDHQRQLVSNLEKKQKKFDQMLAEEKAISARYAEE 623

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  929 REQLEADsqalllAKETLTGELAGLRQQVTATEEKAALDKelmTQKLVQAERETQASLREQRAAHEEDLQRLQREKEAAW 1008
Cdd:pfam01576  624 RDRAEAE------AREKETRALSLARALEEALEAKEELER---TNKQLRAEMEDLVSSKDDVGKNVHELERSKRALEQQV 694

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1009 RELQAERAQLQGQLqqereellarmeaekeelseeiaalqQERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLA 1088
Cdd:pfam01576  695 EEMKTQLEELEDEL--------------------------QATEDAKLRLEVNMQALKAQFERDLQARDEQGEEKRRQLV 748

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1089 AISLEMERQKRDAQSRQEQDRNTVNALTSELRDLRAQLEEATAAH---AQQVKELQEQTGNLGRQREACMREAEELRTQL 1165
Cdd:pfam01576  749 KQVRELEAELEDERKQRAQAVAAKKKLELDLKELEAQIDAANKGReeaVKQLKKLQAQMKDLQRELEEARASRDEILAQS 828

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1166 RLLEDTRDGLRRELLEAQRKVRDSQDSSEAHRQEASELRRSLSEGTKEREALRRSNEELRTAVKKAESERISLKLANEDK 1245
Cdd:pfam01576  829 KESEKKLKNLEAELLQLQEDLAASERARRQAQQERDELADEIASGASGKSALQDEKRRLEARIAQLEEELEEEQSNTELL 908

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1246 EQKLALLEEARMSVAKEAGELRASLQEVERSRLEARRELQELRRQMKTLDSD-NGRLGRELADLQSRLA-LGERTEKESR 1323
Cdd:pfam01576  909 NDRLRKSTLQVEQLTTELAAERSTSQKSESARQQLERQNKELKAKLQEMEGTvKSKFKSSIAALEAKIAqLEEQLEQESR 988
PRK11281 PRK11281
mechanosensitive channel MscK;
579-869 7.92e-05

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 47.98  E-value: 7.92e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  579 TATSVQAQEDAQREaqrlrsaNEILSREKGNLSHSLQVAQ---QQAEDLRQELEKLQA----AQEELRRQHTQLEDQQED 651
Cdd:PRK11281    37 TEADVQAQLDALNK-------QKLLEAEDKLVQQDLEQTLallDKIDRQKEETEQLKQqlaqAPAKLRQAQAELEALKDD 109

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  652 TVQEgarARRELERshRQLEQLEVKRSGLTKELVEVREALSCAVLQRDVLQTEKAEVAEALTKAEAGRAQLELSVTKLRA 731
Cdd:PRK11281   110 NDEE---TRETLST--LSLRQLESRLAQTLDQLQNAQNDLAEYNSQLVSLQTQPERAQAALYANSQRLQQIRNLLKGGKV 184

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  732 EEASLRDSLSKM-----SALNESLAQDKLEL---NRLIAQLEEEKAALLGRQQQAEHATSLAvekQERLEQLRLEQEver 803
Cdd:PRK11281   185 GGKALRPSQRVLlqaeqALLNAQNDLQRKSLegnTQLQDLLQKQRDYLTARIQRLEHQLQLL---QEAINSKRLTLS--- 258

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1958776745  804 qglegslcvAEQAREALGQQILVLRSERSHLQEQVA---QLSRQLNGRDQELDQALRESQRQVEALERA 869
Cdd:PRK11281   259 ---------EKTVQEAQSQDEAARIQANPLVAQELEinlQLSQRLLKATEKLNTLTQQNLRVKNWLDRL 318
mukB PRK04863
chromosome partition protein MukB;
1497-1975 8.93e-05

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 48.03  E-value: 8.93e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1497 DPEAVRDALRDFLQELRSAQRERDELR----VQTSTLSQQLAEMEAERDHAASRAKQLQKAVAESEEAWRSADRRLSGAQ 1572
Cdd:PRK04863   234 DMEAALRENRMTLEAIRVTQSDRDLFKhlitESTNYVAADYMRHANERRVHLEEALELRRELYTSRRQLAAEQYRLVEMA 313

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1573 AELALQEESvrrsrrecratldqmavlersLQATESELRASQEKVNKMKATEVKLESDKRRLKEVLDASEsrsiKLELQR 1652
Cdd:PRK04863   314 RELAELNEA---------------------ESDLEQDYQAASDHLNLVQTALRQQEKIERYQADLEELEE----RLEEQN 368

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1653 RALEGelqrSRLGLGDREAHAQALQDRVDSLQRQVAD-------SEVKAGTLQLTVERLSGA----------LAKVEESE 1715
Cdd:PRK04863   369 EVVEE----ADEQQEENEARAEAAEEEVDELKSQLADyqqaldvQQTRAIQYQQAVQALERAkqlcglpdltADNAEDWL 444

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1716 GTLRSKVQSLTDALAQSSASLTSSQDKNLYLQKALS-----TCEHDRQVLQerlDAARQALSEARRQSSsLGEQVQTLRG 1790
Cdd:PRK04863   445 EEFQAKEQEATEELLSLEQKLSVAQAAHSQFEQAYQlvrkiAGEVSRSEAW---DVARELLRRLREQRH-LAEQLQQLRM 520

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1791 ELANLElQRgdaegqlqqlqqvlrqrqegeavaLRSVQKLQEERRLLQERLGS-------LQRALAQLEAEKRELERSAL 1863
Cdd:PRK04863   521 RLSELE-QR------------------------LRQQQRAERLLAEFCKRLGKnlddedeLEQLQEELEARLESLSESVS 575

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1864 QLDKDRVALRKTLDKvereklrshedtlrLNAERGRLDRTltgaELDLAEAQQQIQHLEAQVVEVLErnhSPVQVEAdeq 1943
Cdd:PRK04863   576 EARERRMALRQQLEQ--------------LQARIQRLAAR----APAWLAAQDALARLREQSGEEFE---DSQDVTE--- 631

                          490       500       510
                   ....*....|....*....|....*....|..
gi 1958776745 1944 hlELQQEVERLRSAQVRTERTLEARERAHRQR 1975
Cdd:PRK04863   632 --YMQQLLERERELTVERDELAARKQALDEEI 661
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
817-1143 9.13e-05

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 47.20  E-value: 9.13e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  817 REALGQQILVLRSERSHLQEQVAQLSRQLNGRDQELDQALRESQRQVEALERAAREKEAMAKERAGLAVQLAAAEREGRT 896
Cdd:COG4372     19 RPKTGILIAALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQ 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  897 LSEETIRLRLEKEALESSLFDVQRQLAQLEARREQLEADSQALLLAKETLTGELAGLRQQVTATEEKAAldkELMTQKLV 976
Cdd:COG4372     99 AQEELESLQEEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELA---ALEQELQA 175

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  977 QAERETQASLREQRAAHEEDLQRLQREKEAAWRELQAERAQLQGQLQQEREELLARMEAEKEELSEEIAALQQERDEGLL 1056
Cdd:COG4372    176 LSEAEAEQALDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEV 255

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1057 LAESEKQQALSLKESEKTALSEKLMGTRHSLAAISLEMERQKRDAQSRQEQDRNTVNALTSELRDLRAQLEEATAAHAQQ 1136
Cdd:COG4372    256 ILKEIEELELAILVEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLELALAIL 335


                   ....*..
gi 1958776745 1137 VKELQEQ 1143
Cdd:COG4372    336 LAELADL 342
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1499-1713 9.20e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.07  E-value: 9.20e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1499 EAVRDALRDFLQELRSAQRERDELRVQTSTLSQQLAEMEAERDHAASRAKQLQKAVAESEEAWRSADRRLSGAQAELALQ 1578
Cdd:COG4942     23 AEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQ 102

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1579 EES----VRRSRRECRATLDQMAVLERSLQATESELRASQEKVNKMKATEVKLESDKRRLKEVLDASESRSIKLELQRRA 1654
Cdd:COG4942    103 KEElaelLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAE 182

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1958776745 1655 LEGELQRSRLGLGDREAHAQALQDRVDSLQRQVADSEVKAGTLQLTVERLSGALAKVEE 1713
Cdd:COG4942    183 LEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAE 241
CHASE3 COG5278
Extracytoplasmic sensor domain CHASE3 (specificity unknown) [Signal transduction mechanisms];
615-1061 1.01e-04

Extracytoplasmic sensor domain CHASE3 (specificity unknown) [Signal transduction mechanisms];


Pssm-ID: 444089 [Multi-domain]  Cd Length: 530  Bit Score: 47.21  E-value: 1.01e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  615 QVAQQQAEDLRQELEKLQAAQEELRRQHTQLEDQQEDTVQEGARARRELERSHRQLEQLEVKRSGLTKELVEVREALSCA 694
Cdd:COG5278     82 EEARAEIDELLAELRSLTADNPEQQARLDELEALIDQWLAELEQVIALRRAGGLEAALALVRSGEGKALMDEIRARLLLL 161

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  695 VLQRDVLQTEKAEVAEALTKAEAGRAQLELSVTKLRAEEASLRDSLSKMSALNESLAQDKLELNRLIAQLEEEKAALLGR 774
Cdd:COG5278    162 ALALAALLLAAAALLLLLLALAALLALAELLLLALARALAALLLLLLLEAELAAAAALLAAAAALAALAALELLAALALA 241

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  775 QQQAEHATSLAVEKQERLEQLRLEQEVERQGLEGSLCVAEQAREALGQQILVLRSERSHLQEQVAQLSRQLNGRDQELDQ 854
Cdd:COG5278    242 LALLLAALLLALLAALALAALLAAALLALAALLLALAAAAALAAAAALELAAAEALALAELELELLLAAAAAAAAAAAAA 321

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  855 ALRESQRQVEALERAAREKEAMAKERAGLAVQLAAAEREGRTLSEETIRLRLEKEALESSLFDVQRQLAQLEARREQLEA 934
Cdd:COG5278    322 AAALAALLALALATALAAAAAALALLAALLAEAAAAAAEEAEAAAEAAAAALAGLAEVEAEGAAEAVELEVLAIAAAAAA 401

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  935 DSQALLLAKETLTGELAGLRQQVTATEEKAALDKELMTQKLVQAERETQASLREQRAAHEEDLQRLQREKEAAWRELQAE 1014
Cdd:COG5278    402 AAAEAAAAAAAAAAASAAEALELAEALAEALALAEEEALALAAASSELAEAGAALALAAAEALAEELAAVAALAALAAAA 481

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*..
gi 1958776745 1015 RAQLQGQLQQEREELLARMEAEKEELSEEIAALQQERDEGLLLAESE 1061
Cdd:COG5278    482 AALAEAEAAAALAAAAALSLALALAALLLAAAEAALAAALAAALASA 528
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 621-1029 1.03e-04

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 47.74  E-value: 1.03e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  621 AEDLRQELEKLQAAQ--------EELRRQHTQLEDQQE--DTVQEGARARRELERSHRQLEQlevKRSGLTKELVEVREA 690
Cdd:PRK10929    25 EKQITQELEQAKAAKtpaqaeivEALQSALNWLEERKGslERAKQYQQVIDNFPKLSAELRQ---QLNNERDEPRSVPPN 101

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  691 LSCAVLQRDVLQTeKAEVAEaltkaEAGRAQLElsvtKLRAEEASlrDSLSKmsalnesLAQDKLELNRLIAQLEEEKAA 770
Cdd:PRK10929   102 MSTDALEQEILQV-SSQLLE-----KSRQAQQE----QDRAREIS--DSLSQ-------LPQQQTEARRQLNEIERRLQT 162

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  771 LLGRQQQAEHATSLAVEKQERLEQLRLEQeverqgLEGSLCVAEQAREALGQQILVLRSERSHLQEQVAQLSRQLNgrdq 850
Cdd:PRK10929   163 LGTPNTPLAQAQLTALQAESAALKALVDE------LELAQLSANNRQELARLRSELAKKRSQQLDAYLQALRNQLN---- 232

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  851 eldqalreSQRQVEAlERAAREKEAMAKERAGLAVQLAAAEREGRTLSEEtirlrLEKEALESSLF-DVQRQLAQ--LEA 927
Cdd:PRK10929   233 --------SQRQREA-ERALESTELLAEQSGDLPKSIVAQFKINRELSQA-----LNQQAQRMDLIaSQQRQAASqtLQV 298

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  928 RREQLEADSQALLLAKETLTGElaGLRQQVTATEEKAaldkelmtqKLVQAERETqASLREQRAAHEEDLQRLQRE---K 1004
Cdd:PRK10929   299 RQALNTLREQSQWLGVSNALGE--ALRAQVARLPEMP---------KPQQLDTEM-AQLRVQRLRYEDLLNKQPQLrqiR 366

                          410       420
                   ....*....|....*....|....*.
gi 1958776745 1005 EAAWRELQAERAQ-LQGQLQQEREEL 1029
Cdd:PRK10929   367 QADGQPLTAEQNRiLDAQLRTQRELL 392
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1212-1445 1.11e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 46.68  E-value: 1.11e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1212 KEREALRRSNEELRTAVKKAESERISLKLANEDKEQKLALLEEARMSVAKEAGELRASLQEVERSRLEARRELQELRRQM 1291
Cdd:COG4942     27 AELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEEL 106

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1292 KTLDSDNGRLGR-----------ELADLQSRLALGERTEKESRREVLGLRQKVLKgessLEALKQELQGSQRKLQEQEAE 1360
Cdd:COG4942    107 AELLRALYRLGRqpplalllspeDFLDAVRRLQYLKYLAPARREQAEELRADLAE----LAALRAELEAERAELEALLAE 182

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1361 FRARERgllgSLEEARGAEKKLLDSarslelrlegVRAETSELGLRLSAAEGRAQGLEVELARVEAQRRVAEAQLGGLRS 1440
Cdd:COG4942    183 LEEERA----ALEALKAERQKLLAR----------LEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGF 248


                   ....*
gi 1958776745 1441 ALRRG 1445
Cdd:COG4942    249 AALKG 253
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
891-1429 1.38e-04

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 46.98  E-value: 1.38e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  891 EREGRTLSEETIRLRLEKEALESSLF---DVQRQLAQLEARREQLEADSQALLLAKETLTGELAGLRQQVTATEEKAALD 967
Cdd:PRK03918   161 ENAYKNLGEVIKEIKRRIERLEKFIKrteNIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEI 240

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  968 KELMTQKL-----VQAERETQASLREQRAAHEEDLQRLqREKEAAWRELQ--AERAQLQGQLQQEREELLARMEAEKEEL 1040
Cdd:PRK03918   241 EELEKELEslegsKRKLEEKIRELEERIEELKKEIEEL-EEKVKELKELKekAEEYIKLSEFYEEYLDELREIEKRLSRL 319

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1041 SEEIAALQQERDEglllaesekqqaLSLKESEKTALSEKLMGTRHSLAAISlEMERQKRDAQSRQEQDRNTVNALTS-EL 1119
Cdd:PRK03918   320 EEEINGIEERIKE------------LEEKEERLEELKKKLKELEKRLEELE-ERHELYEEAKAKKEELERLKKRLTGlTP 386

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1120 RDLRAQLEEATAAHaqqvKELQEQTGNLGRQREACMREAEELRTQLRLLEDTRDGL---RRELLEAQRKvrdsqDSSEAH 1196
Cdd:PRK03918   387 EKLEKELEELEKAK----EEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCpvcGRELTEEHRK-----ELLEEY 457

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1197 RQEASELRRSLSEGTKEREALRRSNEELRTAVKKAESERISLKLANEDKEQKLAL----LEEARMSvAKEAGELRASLQE 1272
Cdd:PRK03918   458 TAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQLKELEEKLkkynLEELEKK-AEEYEKLKEKLIK 536

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1273 VE---RSRLEARRELQELRRQMKTLDSDNGRLGRELADLQSRLA-LGERTEKESRREVLGLRQ------KVLKGESSLEA 1342
Cdd:PRK03918   537 LKgeiKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEeLGFESVEELEERLKELEPfyneylELKDAEKELER 616

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1343 LKQELQGSQRKLQEQEAEF---RARERGLLGSLEEARGA-----EKKLLDSARSLELRLEGVRAETSELGLRLSAAEGRA 1414
Cdd:PRK03918   617 EEKELKKLEEELDKAFEELaetEKRLEELRKELEELEKKyseeeYEELREEYLELSRELAGLRAELEELEKRREEIKKTL 696

                          570
                   ....*....|....*
gi 1958776745 1415 QGLEVELARVEAQRR 1429
Cdd:PRK03918   697 EKLKEELEEREKAKK 711
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 877-1357 1.57e-04

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 46.87  E-value: 1.57e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  877 AKERAGLAVQLAAAEREGRTLSEEtirLRLEKEALEsslfDVQRQLAQLEARREQLEADSQAlllAKETLTGELAGLRQQ 956
Cdd:COG3096    277 ANERRELSERALELRRELFGARRQ---LAEEQYRLV----EMARELEELSARESDLEQDYQA---ASDHLNLVQTALRQQ 346

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  957 VTATEEKAALDKelMTQKLVQAEretqaslrEQRAAHEEDLQRLQREKEAAWRELQAERAQLqGQLQQEREELLARmeae 1036
Cdd:COG3096    347 EKIERYQEDLEE--LTERLEEQE--------EVVEEAAEQLAEAEARLEAAEEEVDSLKSQL-ADYQQALDVQQTR---- 411

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1037 keelseeiaALQQerdeglllaesekQQALSLKESEKTALSeklmgtrhsLAAISLEmerqkrDAQSRQEQDRNTVNALT 1116
Cdd:COG3096    412 ---------AIQY-------------QQAVQALEKARALCG---------LPDLTPE------NAEDYLAAFRAKEQQAT 454

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1117 SELRDLRAQLEEATAAHAQQVKELQEQTGNLGR-QREACMREAEELRTQ---LRLLEDTRDGLRRELLEAQRKVRdsqds 1192
Cdd:COG3096    455 EEVLELEQKLSVADAARRQFEKAYELVCKIAGEvERSQAWQTARELLRRyrsQQALAQRLQQLRAQLAELEQRLR----- 529

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1193 seaHRQEASELRRSLSegtkerealRRSNEELRTAvkkaeserislklanEDKEQKLALLEEARMSVAKEAGELRASLQE 1272
Cdd:COG3096    530 ---QQQNAERLLEEFC---------QRIGQQLDAA---------------EELEELLAELEAQLEELEEQAAEAVEQRSE 582

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1273 VERSRLEARRELQELRRQMKTLdsdngrlgRELADLQSRLALGERTEKESRREVLGLRQKVLKGESSLEALKQELQGSQR 1352
Cdd:COG3096    583 LRQQLEQLRARIKELAARAPAW--------LAAQDALERLREQSGEALADSQEVTAAMQQLLEREREATVERDELAARKQ 654


                   ....*
gi 1958776745 1353 KLQEQ 1357
Cdd:COG3096    655 ALESQ 659
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 1194-1867 1.60e-04

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 47.14  E-value: 1.60e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1194 EAHRQEASELRRSLSEGTKEREALRRSNEELRTAVKKAESERISLKLANEDKEQKLALLEEARMSVAKEAGELRASLQEV 1273
Cdd:pfam12128  269 SDETLIASRQEERQETSAELNQLLRTLDDQWKEKRDELNGELSAADAAVAKDRSELEALEDQHGAFLDADIETAAADQEQ 348

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1274 ERSrleARRELQELRRQMKTLDSDNGRLGRELADLQSRLALgertekESRREVLGLRQKVlkgESSLEALKQELQGSQRK 1353
Cdd:pfam12128  349 LPS---WQSELENLEERLKALTGKHQDVTAKYNRRRSKIKE------QNNRDIAGIKDKL---AKIREARDRQLAVAEDD 416

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1354 LQEQEAEFRARergLLGSLEEARGAEKKLLDSARSLELRLEGVRAeTSELGLRLSAAEGRAQGLEVELARVEAQRRVA-- 1431
Cdd:pfam12128  417 LQALESELREQ---LEAGKLEFNEEEYRLKSRLGELKLRLNQATA-TPELLLQLENFDERIERAREEQEAANAEVERLqs 492

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1432 -EAQLGGLRSALRRGLGLGRVSSSPAREAPAGGSGDGLSSPSPLEYSPRSQPP----SPGPVASPA---PPDLDPEAVRD 1503
Cdd:pfam12128  493 eLRQARKRRDQASEALRQASRRLEERQSALDELELQLFPQAGTLLHFLRKEAPdweqSIGKVISPEllhRTDLDPEVWDG 572

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1504 ALRDFLQ----ELRSAQRERDELRVQTSTLSQQLAEMEAERDHAASRAKQLQKAVAESEEAWRSADRRLSGAQAELALQE 1579
Cdd:pfam12128  573 SVGGELNlygvKLDLKRIDVPEWAASEEELRERLDKAEEALQSAREKQAAAEEQLVQANGELEKASREETFARTALKNAR 652

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1580 ESVRRSRRECRATLDQMAvlerslQATESELRASQEKVNKMKATEVKLESDKRRLKEVL--DASESRSIKLElQRRALEG 1657
Cdd:pfam12128  653 LDLRRLFDEKQSEKDKKN------KALAERKDSANERLNSLEAQLKQLDKKHQAWLEEQkeQKREARTEKQA-YWQVVEG 725

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1658 ELQRSRLGLGDREAHAQ-ALQDRVDSLQRQVADSEVKAGTLQLTVERLSGALAKVEesegtlrskvQSLTDALAQSSASL 1736
Cdd:pfam12128  726 ALDAQLALLKAAIAARRsGAKAELKALETWYKRDLASLGVDPDVIAKLKREIRTLE----------RKIERIAVRRQEVL 795

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1737 TssqdknlYLQKALSTCEHDRQVLQERLDAARQALSEARRQsssLGEQVQTLRGELANLELQRGDAEgqlqqlqqVLRQR 1816
Cdd:pfam12128  796 R-------YFDWYQETWLQRRPRLATQLSNIERAISELQQQ---LARLIADTKLRRAKLEMERKASE--------KQQVR 857

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1958776745 1817 QEGEAVALRSVQKLQEERRLLQ---ERLGSLQRALAQLEAEKRELERSALQLDK 1867
Cdd:pfam12128  858 LSENLRGLRCEMSKLATLKEDAnseQAQGSIGERLAQLEDLKLKRDYLSESVKK 911
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 855-1029 1.70e-04

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 45.30  E-value: 1.70e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  855 ALRESQRQVEALERAAREKEAMAKERAGLAVQLAAAEREGRTLSEETIRLRLEKEALESSLFDVQRQLAQLEARREQLEA 934
Cdd:COG1579      1 AMPEDLRALLDLQELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEE 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  935 DSQALLLAKE--TLTGELAGLRQQVTATEEKAaldKELMTQklVQAERETQASLREQRAAHEEDLQRLQREKEAAWRELQ 1012
Cdd:COG1579     81 QLGNVRNNKEyeALQKEIESLKRRISDLEDEI---LELMER--IEELEEELAELEAELAELEAELEEKKAELDEELAELE 155

                          170
                   ....*....|....*..
gi 1958776745 1013 AERAQLQGQLQQEREEL 1029
Cdd:COG1579    156 AELEELEAEREELAAKI 172
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1092-1619 1.78e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 46.83  E-value: 1.78e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1092 LEMERQKRDAQSRQEQDRNTVNALTSELRDLRAQLEEATAAHAQQVKELQEQtgnlgrQREACMREAEELRTQLRLLEDT 1171
Cdd:COG4913    244 LEDAREQIELLEPIRELAERYAAARERLAELEYLRAALRLWFAQRRLELLEA------ELEELRAELARLEAELERLEAR 317

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1172 RDGLRRELLEAQRKVRDSQDsseahrQEASELRRSLSEGTKEREALRRSNEELRTAVK----KAESERISLKLANEDKEQ 1247
Cdd:COG4913    318 LDALREELDELEAQIRGNGG------DRLEQLEREIERLERELEERERRRARLEALLAalglPLPASAEEFAALRAEAAA 391

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1248 KLALLEEARMSVAKEAGELRASLQEVERSRLEARRELQELRRQMKTLDSDNGRLGRELAD---------------LQSR- 1311
Cdd:COG4913    392 LLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALRDALAEalgldeaelpfvgelIEVRp 471

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1312 ----------LALG---------ERTEKESRREV----LGLR---QKVLKGESSLEALKQELQGSQRKLQEQEAEFRARE 1365
Cdd:COG4913    472 eeerwrgaieRVLGgfaltllvpPEHYAAALRWVnrlhLRGRlvyERVRTGLPDPERPRLDPDSLAGKLDFKPHPFRAWL 551

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1366 RGLLG---------SLEEARGAEKKLL------DSARSLELRLEGVRAETSELGL----RLSAAEGRAQGLEVELARVEA 1426
Cdd:COG4913    552 EAELGrrfdyvcvdSPEELRRHPRAITragqvkGNGTRHEKDDRRRIRSRYVLGFdnraKLAALEAELAELEEELAEAEE 631

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1427 QRRVAEAQLGGLRSALRRGLGLGRVSSSPAREAPAggsgdglsspspleysprsqppspgpvaspappdldpEAVRDALR 1506
Cdd:COG4913    632 RLEALEAELDALQERREALQRLAEYSWDEIDVASA-------------------------------------EREIAELE 674

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1507 DFLQELRSAQRERDELRVQTSTLSQQLAEMEAERDHAASRAKQLQKAVAESEEAWRSADRRLSGAQAELALQE----ESV 1582
Cdd:COG4913    675 AELERLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELrallEER 754

                          570       580       590
                   ....*....|....*....|....*....|....*..
gi 1958776745 1583 RRSRRECRATLDQMAVLERSLQATESELRASQEKVNK 1619
Cdd:COG4913    755 FAAALGDAVERELRENLEERIDALRARLNRAEEELER 791
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1495-1913 1.92e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 46.57  E-value: 1.92e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1495 DLDPEAVRDALRDFLQELRSAQRERDELRVQTSTLSQQLAEMEAERDHAASRAKQLQKAVAESEEAWRSADRRLSGAQAE 1574
Cdd:PRK02224   306 DADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREE 385

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1575 LALQEESVRRSRRECRATLDQMAVLERSLQATESELRASQEKVNKMKATEVKLESDKRRLKEVLDASESRSIKLELQRRA 1654
Cdd:PRK02224   386 IEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTARERVEEAEALLEAGKCPECGQPVEGSP 465

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1655 LEGELQRSRlglgdreahaqalqDRVDSLQRQVADSEVKAGTLQLTVERLSgALAKVEESEGTLRSKVQSLTDALAQSSA 1734
Cdd:PRK02224   466 HVETIEEDR--------------ERVEELEAELEDLEEEVEEVEERLERAE-DLVEAEDRIERLEERREDLEELIAERRE 530

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1735 SLTSSQDKNLYLQKALSTCEHDRQVLQERLDAARQALSEARRQSSSLGEQVQTLRGELANLELQRGDAEGQLQQLQQVLR 1814
Cdd:PRK02224   531 TIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLERIRTLLAAIADAEDEIER 610

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1815 QRQEGEAVAlrsvqKLQEERRllqERLGSLQRALAQLEAEKRELERSALQLDKDRVAlrKTLDKVErEKLRshedtlRLN 1894
Cdd:PRK02224   611 LREKREALA-----ELNDERR---ERLAEKRERKRELEAEFDEARIEEAREDKERAE--EYLEQVE-EKLD------ELR 673

                          410
                   ....*....|....*....
gi 1958776745 1895 AERGRLDRTLTGAELDLAE 1913
Cdd:PRK02224   674 EERDDLQAEIGAVENELEE 692
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1044-1301 2.19e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.91  E-value: 2.19e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1044 IAALQQERDEgLLLAESEKQQALSLKESEKTALSEKLMGTRHSLAAIslemERQKRDAQSRQEQDRNTVNALTSELRDLR 1123
Cdd:COG4942     22 AAEAEAELEQ-LQQEIAELEKELAALKKEEKALLKQLAALERRIAAL----ARRIRALEQELAALEAELAELEKEIAELR 96

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1124 AQLEEATAAHAQQVKELQEQtgnlgrqreacmreaeELRTQLRLLEDTRDglrreLLEAQRKVRDSQDSSEAHRQEASEL 1203
Cdd:COG4942     97 AELEAQKEELAELLRALYRL----------------GRQPPLALLLSPED-----FLDAVRRLQYLKYLAPARREQAEEL 155

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1204 RRSLSEGTKEREALRRSNEELRTAVKKAESERISLKLANEDKEQKLALLEEARMSVAKEAGELRASLQEVER--SRLEAR 1281
Cdd:COG4942    156 RADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEAliARLEAE 235

                          250       260
                   ....*....|....*....|
gi 1958776745 1282 RELQELRRQMKTLDSDNGRL 1301
Cdd:COG4942    236 AAAAAERTPAAGFAALKGKL 255
PRK11637 PRK11637
AmiB activator; Provisional
 618-873 2.20e-04

AmiB activator; Provisional


Pssm-ID: 236942 [Multi-domain]  Cd Length: 428  Bit Score: 45.84  E-value: 2.20e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  618 QQQAEDLRQELEKLQAAQEELRRQHTQLEDQQEDTVQEGARARRELERSHRQLEQLEVKRSGLTKelvevrealSCAVLQ 697
Cdd:PRK11637    46 RDQLKSIQQDIAAKEKSVRQQQQQRASLLAQLKKQEEAISQASRKLRETQNTLNQLNKQIDELNA---------SIAKLE 116

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  698 RDVLQTEK---AEVAEALTKAEAGRAQLELSvtklraEEASLRDS--LSKMSALNESLAQDKLELNRLIAQLEEEKAALL 772
Cdd:PRK11637   117 QQQAAQERllaAQLDAAFRQGEHTGLQLILS------GEESQRGEriLAYFGYLNQARQETIAELKQTREELAAQKAELE 190

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  773 GRQQQAEHATSLAVEKQERLEQLRLEQEVERQGLEGSLcvaeqarEALGQQILVLRSERSHLQEQVAQLSRQLNGR-DQE 851
Cdd:PRK11637   191 EKQSQQKTLLYEQQAQQQKLEQARNERKKTLTGLESSL-------QKDQQQLSELRANESRLRDSIARAEREAKARaERE 263

                          250       260
                   ....*....|....*....|..
gi 1958776745  852 LDQALRESQRQVEALERAAREK 873
Cdd:PRK11637   264 AREAARVRDKQKQAKRKGSTYK 285
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
536-810 2.66e-04

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 45.66  E-value: 2.66e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  536 QVQDMRGRYEASQDLLGSVRKQLSDSEGERRGLEEQLQRLRDQTATSVQAQEDAQREAQRLRSANEILSREkgnlshsLQ 615
Cdd:COG4372     32 QLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEE-------LE 104

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  616 VAQQQAEDLRQELEKLQAAQEELRRQHTQLEDQQEDTVQEGARARRELERSHRQLEQLEVKRSGLTKELVEVREALSCAV 695
Cdd:COG4372    105 SLQEEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAEAEQA 184

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  696 LQRDVLQTEKAEVAEALTKAEAGRAQLELSVTKLRAEEASLRDSLSKMSALNESLAQDKLELNRLIAQLEEEKAALLGRQ 775
Cdd:COG4372    185 LDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELE 264

                          250       260       270
                   ....*....|....*....|....*....|....*
gi 1958776745  776 QQAEHATSLAVEKQERLEQLRLEQEVERQGLEGSL 810
Cdd:COG4372    265 LAILVEKDTEEEELEIAALELEALEEAALELKLLA 299
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1170-1689 2.75e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 46.19  E-value: 2.75e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1170 DTRDGLRRelLEAQRKVRDSQDSSEAHRQEASELRRSLSEGTKEREALRRSNEELRTAVKKAESERISLKLANEDKEQKL 1249
Cdd:PRK02224   173 DARLGVER--VLSDQRGSLDQLKAQIEEKEEKDLHERLNGLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERR 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1250 ALLEEarmsVAKEAGELRASLQEVERSRLEARRELQELRRQMKTLDSDNgrlgrelADLQSRLALGErtekeSRREVLGL 1329
Cdd:PRK02224   251 EELET----LEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEER-------DDLLAEAGLDD-----ADAEAVEA 314

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1330 RQkvlkgeSSLEALKQELQGSQRKLQEQEAEFRARERGLLGSLEEARGAEKKLLDSARSLELRLEGVRAETSELGLRLSA 1409
Cdd:PRK02224   315 RR------EELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEE 388

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1410 AEGRAQGLEVELARVEAQRRVAEAQLGGL---RSALRRGLGLGRVSSSPAREAPAGG-----SGDGLSSPSPLEYSPR-- 1479
Cdd:PRK02224   389 LEEEIEELRERFGDAPVDLGNAEDFLEELreeRDELREREAELEATLRTARERVEEAealleAGKCPECGQPVEGSPHve 468

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1480 SQPPSPGPVASPAPPDLDPEAVRDALR---DFLQELRSAQRERDELRVQTSTLSQQLAEMEAERDHAASRAKQLQKAVAE 1556
Cdd:PRK02224   469 TIEEDRERVEELEAELEDLEEEVEEVEerlERAEDLVEAEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAE 548

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1557 SE---EAWRSADRRLSGAQAELALQEESVRRSRRECRATLDQMAVLERSLQATESELRASQEKVNKMKATEVKLESDKRR 1633
Cdd:PRK02224   549 LEaeaEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLERIRTLLAAIADAEDEIERLREKREALAELNDERRER 628

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1958776745 1634 LKEVLDasesrsiklelQRRALEGELQrsrlglGDREAHAQALQDRVDSLQRQVAD 1689
Cdd:PRK02224   629 LAEKRE-----------RKRELEAEFD------EARIEEAREDKERAEEYLEQVEE 667
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 961-1169 2.97e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.53  E-value: 2.97e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  961 EEKAALDKELM-TQKLVQAERETQASLREQRAAHEEDLQRLQREKEAAWRELQAERAQLQgQLQQEREELLARMEAEKEE 1039
Cdd:COG4942     27 AELEQLQQEIAeLEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELA-ELEKEIAELRAELEAQKEE 105

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1040 LSEEIAALQQ--ERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLAAISLEMERQKRDaqsrQEQDRNTVNALTS 1117
Cdd:COG4942    106 LAELLRALYRlgRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAE----LEAERAELEALLA 181

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1958776745 1118 ELRDLRAQLEEATAAHAQQVKELQEQTGNLGRQREACMREAEELRTQLRLLE 1169
Cdd:COG4942    182 ELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLE 233
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
 903-1014 3.24e-04

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 45.84  E-value: 3.24e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  903 RLRLEKEALESSLFDVQRQLAQLEARREQLEADSQALLLAK-ETLTGELAGLRQQVTATEEKAALDKELMTQklVQAERE 981
Cdd:COG0542    401 RVRMEIDSKPEELDELERRLEQLEIEKEALKKEQDEASFERlAELRDELAELEEELEALKARWEAEKELIEE--IQELKE 478

                           90       100       110
                   ....*....|....*....|....*....|...
gi 1958776745  982 TQASLREQRAAHEEDLQRLQREKEAAWRELQAE 1014
Cdd:COG0542    479 ELEQRYGKIPELEKELAELEEELAELAPLLREE 511
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1756-1984 3.65e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.14  E-value: 3.65e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1756 DRQVLQERLDAARQALSEARRQSSSLGEQVQTLRGELANLELQRGDAEgqlqqlqqvlrqrqegeavalRSVQKLQEERR 1835
Cdd:COG4942     21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALA---------------------RRIRALEQELA 79

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1836 LLQERLGSLQRALAQLEAEKRELErsalQLDKDRVALRKTLDKVEREKLRSHEDTLRLNAERGRLDRTLTGAELDLAEAQ 1915
Cdd:COG4942     80 ALEAELAELEKEIAELRAELEAQK----EELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEEL 155

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1958776745 1916 QQIQHLEAQVVEVLERNHSPVQVEADEQhLELQQEVERLRSAQVRTERTLEARERAHRQRVSGLEEQVQ 1984
Cdd:COG4942    156 RADLAELAALRAELEAERAELEALLAEL-EEERAALEALKAERQKLLARLEKELAELAAELAELQQEAE 223
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 774-1022 3.95e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.14  E-value: 3.95e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  774 RQQQAEHATSLAVEKQERLEQLRLEQEVERQGLEGSLCVAEQAREALGQQILVLRSERSHLQEQVAQLSRQLNGRDQELD 853
Cdd:COG4942     21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELE 100

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  854 QALRESQRQVEALERAAREKEAMAKERAGLAVQLAAAEREGRTLSEetirlrlekeALESSLFDVQRQLAQLEARREQLE 933
Cdd:COG4942    101 AQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAP----------ARREQAEELRADLAELAALRAELE 170

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  934 ADSQALLLAKETLTGELAGLRQQVtatEEKAALDKELMTQKlvQAERETQASLREQRAAHEEDLQRLQREKEAAWRELQA 1013
Cdd:COG4942    171 AERAELEALLAELEEERAALEALK---AERQKLLARLEKEL--AELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245

                          250
                   ....*....|
gi 1958776745 1014 ER-AQLQGQL 1022
Cdd:COG4942    246 AGfAALKGKL 255
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 603-1072 3.95e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 45.40  E-value: 3.95e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  603 LSREKGNLSHSLQVAQQQAEDLRQELEKLQAAQEELRRQHTQLEDQQEDTVQEGARARRELERSHRQLEQLEVKRSGLTK 682
Cdd:TIGR04523  223 LKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNN 302

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  683 E-----LVEVREALSCAVLQRDVLQTEKAEVAEALTKAEAGRAQLELSVTKLRAEEASLRDSLSKMSALNESLAQDKLEL 757
Cdd:TIGR04523  303 QkeqdwNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSY 382

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  758 NRLIAQLEEEKAALlgrQQQAEHATSLAVEKQERLEQLRLEQEVerqglegslcvAEQAREALGQQILVLRSERSHLQEQ 837
Cdd:TIGR04523  383 KQEIKNLESQINDL---ESKIQNQEKLNQQKDEQIKKLQQEKEL-----------LEKEIERLKETIIKNNSEIKDLTNQ 448

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  838 VAQLSRQLNgrdqELDQALRESQRQVEALERAAREKEAmakeraglavQLAAAEREGRTLSEETIRLRLEKEALESSLFD 917
Cdd:TIGR04523  449 DSVKELIIK----NLDNTRESLETQLKVLSRSINKIKQ----------NLEQKQKELKSKEKELKKLNEEKKELEEKVKD 514

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  918 VQRQLAQLEARREQLEADSQALLLAKETLTGELAGLRQQVTATEEKAALDKElmTQKLVQAERETQASLREQRAAhEEDL 997
Cdd:TIGR04523  515 LTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELKKENLEKEIDEK--NKEIEELKQTQKSLKKKQEEK-QELI 591

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1958776745  998 QRLQREKEAAWRELqAERAQLQGQLQQEREELlarmEAEKEELSEEIAALQQERDEGLLLAESEKQQALSLKESE 1072
Cdd:TIGR04523  592 DQKEKEKKDLIKEI-EEKEKKISSLEKELEKA----KKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKEIRNKW 661
CHASE3 COG5278
Extracytoplasmic sensor domain CHASE3 (specificity unknown) [Signal transduction mechanisms];
696-1153 4.01e-04

Extracytoplasmic sensor domain CHASE3 (specificity unknown) [Signal transduction mechanisms];


Pssm-ID: 444089 [Multi-domain]  Cd Length: 530  Bit Score: 45.28  E-value: 4.01e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  696 LQRDVLQTEKAEVAEALTKAEAGRAQLELSVTKLRAEEASLRDSLSKMSALNESLAQDKLELNRLIAQLEEEKAALLGRQ 775
Cdd:COG5278     55 LLSALLDAETGQRGYLLTGDESFLEPYEEARAEIDELLAELRSLTADNPEQQARLDELEALIDQWLAELEQVIALRRAGG 134

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  776 QQAEHATSLAVEKQERLEQLRLEQEVERQGLEGSLCVAEQAREALGQQILVLRSERSHLQEQVAQLSRQLNGRDQELDQA 855
Cdd:COG5278    135 LEAALALVRSGEGKALMDEIRARLLLLALALAALLLAAAALLLLLLALAALLALAELLLLALARALAALLLLLLLEAELA 214

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  856 LRESQRQVEALERAAREKEAMAKERAGLAVQLAAAEREGRTLSEETIRLRLEKEALESSLFDVQRQLAQLEARREQLEAD 935
Cdd:COG5278    215 AAAALLAAAAALAALAALELLAALALALALLLAALLLALLAALALAALLAAALLALAALLLALAAAAALAAAAALELAAA 294

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  936 SQALLLAKETLTGELAGLRQQVTATEEKAALDKELMTQKLVQAERETQASLREQRAAHEEDLQRLQREKEAAWRELQAER 1015
Cdd:COG5278    295 EALALAELELELLLAAAAAAAAAAAAAAAALAALLALALATALAAAAAALALLAALLAEAAAAAAEEAEAAAEAAAAALA 374

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1016 AQLQGQLQQEREELLARMEAEKEELSEEIAALQQERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLAAISLEME 1095
Cdd:COG5278    375 GLAEVEAEGAAEAVELEVLAIAAAAAAAAAEAAAAAAAAAAASAAEALELAEALAEALALAEEEALALAAASSELAEAGA 454

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1958776745 1096 RQKRDAQSRQEQDRNTVNALTSELRDLRAQLEEATAAHAQQVKELQEQTGNLGRQREA 1153
Cdd:COG5278    455 ALALAAAEALAEELAAVAALAALAAAAAALAEAEAAAALAAAAALSLALALAALLLAA 512
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 711-939 4.12e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.14  E-value: 4.12e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  711 ALTKAEAGRAQLELSVTKLRAEEASLRDSLSKMSALNESLAQDKLELNRLIAQLEEEKAALlgrQQQAEHATSLAVEKQE 790
Cdd:COG4942     14 AAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRAL---EQELAALEAELAELEK 90

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  791 RLEQLRLEQEVERQGLEGSLcVAEQAREALGQQILVLRSERSHLQEQVAQLSRQLNGRDQELDQALRESQRQVEALeraa 870
Cdd:COG4942     91 EIAELRAELEAQKEELAELL-RALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAAL---- 165

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1958776745  871 reKEAMAKERAGLAVQLAAAEREGRTLSEETIRLRLEKEALESSLFDVQRQLAQLEARREQLEADSQAL 939
Cdd:COG4942    166 --RAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARL 232
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 562-883 4.90e-04

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 44.89  E-value: 4.90e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  562 EGERRGLEEQLQRLRDQTATSVQAQEDAQREAQRLRSANEILSREKGNLSHSLQVAQQQAEDLRQELEKLQAAQEELRRQ 641
Cdd:pfam07888   72 ERQRRELESRVAELKEELRQSREKHEELEEKYKELSASSEELSEEKDALLAQRAAHEARIRELEEDIKTLTQRVLERETE 151

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  642 HTQLEDQQEDTVQEGARARRELERSHRQLEQLEVKRSGLTKELVEVREALSCAVLQRDVLQTEKAEVAEALTKAEAGRAQ 721
Cdd:pfam07888  152 LERMKERAKKAGAQRKEEEAERKQLQAKLQQTEEELRSLSKEFQELRNSLAQRDTQVLQLQDTITTLTQKLTTAHRKEAE 231

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  722 LELSVTKLRAEEASLRDSLSKMSALNESLAQDKLELNRLIAQLEEekaallGRQQQAEHATSLAvEKQERLEQLRLEQEV 801
Cdd:pfam07888  232 NEALLEELRSLQERLNASERKVEGLGEELSSMAAQRDRTQAELHQ------ARLQAAQLTLQLA-DASLALREGRARWAQ 304

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  802 ERQGLEGSLCVAEQAREALGQQIL----VLRSERSHLQEQVAQLSRQLNGRDQELDQALRESQRQVEALERAAREKEAMA 877
Cdd:pfam07888  305 ERETLQQSAEADKDRIEKLSAELQrleeRLQEERMEREKLEVELGREKDCNRVQLSESRRELQELKASLRVAQKEKEQLQ 384


                   ....*.
gi 1958776745  878 KERAGL 883
Cdd:pfam07888  385 AEKQEL 390
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
529-956 4.93e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 45.14  E-value: 4.93e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  529 ALHKRQLQVQDMRGRYEASQDLLGSVRKQLSDSEGERRGLEEQLQRLRDQTATSVQAQEDAQREAQRLRSANEilsREKG 608
Cdd:COG4717    119 EKLEKLLQLLPLYQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATE---EELQ 195

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  609 NLSHSLQVAQQQAEDLRQELEKLQAAQEELRRQHTQLEDQQEDTVQEgararrelershRQLEQLEVKRSGLTkelvevr 688
Cdd:COG4717    196 DLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALE------------ERLKEARLLLLIAA------- 256

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  689 eALSCAVLQRDVLQTEKAEVAEALTKAEAGRAQLELSVTKLRAEEASLRDSLSKMSAL----NESLAQDKLELNRLIAQL 764
Cdd:COG4717    257 -ALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALeeleEEELEELLAALGLPPDLS 335

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  765 EEEKAALLGRQQQAEHATSLAVEKQERLEQLRLEQEVErQGLEGSLCVAEQAREALGQQIlvlrSERSHLQEQVAQLSRQ 844
Cdd:COG4717    336 PEELLELLDRIEELQELLREAEELEEELQLEELEQEIA-ALLAEAGVEDEEELRAALEQA----EEYQELKEELEELEEQ 410

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  845 LNGRDQELDQALresqrqvealerAAREKEAMAKERAGLAVQLAAAEREGRTLSEETIRLRLEKEALESS--LFDVQRQL 922
Cdd:COG4717    411 LEELLGELEELL------------EALDEEELEEELEELEEELEELEEELEELREELAELEAELEQLEEDgeLAELLQEL 478

                          410       420       430
                   ....*....|....*....|....*....|....
gi 1958776745  923 AQLEARREQLEADSQALLLAKETLTGELAGLRQQ 956
Cdd:COG4717    479 EELKAELRELAEEWAALKLALELLEEAREEYREE 512
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1175-1708 5.01e-04

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 45.05  E-value: 5.01e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1175 LRRELLEAQRKVRDSQDSSEAHRQEASELRRSLSEGTKEREALRRSNEELRTAVKKAESERISLklanEDKEQKLALLEE 1254
Cdd:PRK03918   170 VIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKEL----EELKEEIEELEK 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1255 ARMSVAKEAGELRASLQEVERSRLEARRELQELRRQMKTLDSDngrlgRELADLQSRLalgerteKESRREVLGLRQKVL 1334
Cdd:PRK03918   246 ELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKEL-----KEKAEEYIKL-------SEFYEEYLDELREIE 313

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1335 KGESSLEALKQELQGSQRKLQEQEA---EFRARERGLLGSLEEARGAEkKLLDSARSLELRLEGVRAETSELGL-----R 1406
Cdd:PRK03918   314 KRLSRLEEEINGIEERIKELEEKEErleELKKKLKELEKRLEELEERH-ELYEEAKAKKEELERLKKRLTGLTPeklekE 392

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1407 LSAAEGRAQGLEVELARVEAQRRVAEAQLGGLRSALRRGLGLGRVSSSPAREapaggsgdglsspspleysprsqppspg 1486
Cdd:PRK03918   393 LEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCGRE---------------------------- 444

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1487 pvaspappdLDPEAVRDALRDFLQELRSAQRERDELRVQTSTLSQQLAEMEAERDHAASRAKQLQKAvaeseEAWRSADR 1566
Cdd:PRK03918   445 ---------LTEEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELA-----EQLKELEE 510

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1567 RLSGaqaelaLQEESVRRSRRECRATLDQMAVLERSLQATESELRASQEKVNKMKATEVKLESDKRRLKEVLDASESRSI 1646
Cdd:PRK03918   511 KLKK------YNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGF 584

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958776745 1647 K----LELQRRALEgELQRSRLGLGDREAHAQALQDRVDSLQRQVADSEVKAGTLQLTVERLSGAL 1708
Cdd:PRK03918   585 EsveeLEERLKELE-PFYNEYLELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKEL 649
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 620-1031 5.07e-04

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 44.89  E-value: 5.07e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  620 QAEDLRQELEKLQAAQEELRRQHTQLEDQQEDTVQEGARARRELERSHRQLEqlevkrsgltkelvevrealscavlqrd 699
Cdd:pfam07888   28 RAELLQNRLEECLQERAELLQAQEAANRQREKEKERYKRDREQWERQRRELE---------------------------- 79

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  700 vlqtekaevaEALTKAEAGRAQLELSVTKLRAEEASLRDSLSKMSALNESLAQDKLELNRLIAQLEEEKAALLGRQQQAE 779
Cdd:pfam07888   80 ----------SRVAELKEELRQSREKHEELEEKYKELSASSEELSEEKDALLAQRAAHEARIRELEEDIKTLTQRVLERE 149

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  780 HATSLAVEKQERLEQLRLEQEVERQGLEGSLCVAEQAREALGQQILVLRSERSHLQEQVAQLSRQLNGRDQELDQAlres 859
Cdd:pfam07888  150 TELERMKERAKKAGAQRKEEEAERKQLQAKLQQTEEELRSLSKEFQELRNSLAQRDTQVLQLQDTITTLTQKLTTA---- 225

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  860 qrqvealERAAREKEAMAKERAGLAVQLAAAEREGRTLSEETIRLRLEKEALESSLFDVQRQLAQLEArreQLEADSQAL 939
Cdd:pfam07888  226 -------HRKEAENEALLEELRSLQERLNASERKVEGLGEELSSMAAQRDRTQAELHQARLQAAQLTL---QLADASLAL 295

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  940 LLAKETLTGELAGLRQQVTATEEK-AALDKELMTQKLVQAERETQASLREQRAAHEEDLQRLQREKeaAWRELQAERAQL 1018
Cdd:pfam07888  296 REGRARWAQERETLQQSAEADKDRiEKLSAELQRLEERLQEERMEREKLEVELGREKDCNRVQLSE--SRRELQELKASL 373

                          410
                   ....*....|...
gi 1958776745 1019 QgQLQQEREELLA 1031
Cdd:pfam07888  374 R-VAQKEKEQLQA 385
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 544-1102 6.54e-04

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 44.71  E-value: 6.54e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  544 YEASQDLLGSVRKQLSDSEGERRGLEEQLQRLRDQTATSVQAQEDAQREAQRLRSANEILSRekgnlshSLQVAQQQAED 623
Cdd:pfam05483  221 HEKIQHLEEEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKANQLEEKTKLQDE-------NLKELIEKKDH 293

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  624 LRQELEKLQAAQEELRRQHTQLEDQQEDTVQEGARARRELERSHRQLEQLEVKRSGLTKELvevrEALSCAV---LQRDV 700
Cdd:pfam05483  294 LTKELEDIKMSLQRSMSTQKALEEDLQIATKTICQLTEEKEAQMEELNKAKAAHSFVVTEF----EATTCSLeelLRTEQ 369

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  701 LQTEKAEVAEALTKAEAGRAQLELS-VTKLRAEEASLRDSLSKMSALNESLAQDKLELNRLIAQLEEEKAALLGRQQQAE 779
Cdd:pfam05483  370 QRLEKNEDQLKIITMELQKKSSELEeMTKFKNNKEVELEELKKILAEDEKLLDEKKQFEKIAEELKGKEQELIFLLQARE 449

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  780 --------HATSLAVEKQERLEQLR-LEQEVERQGLEGSLCVAEQAREALGQQILVlrSERSHLQEQVAQLSRQLNGRDQ 850
Cdd:pfam05483  450 keihdleiQLTAIKTSEEHYLKEVEdLKTELEKEKLKNIELTAHCDKLLLENKELT--QEASDMTLELKKHQEDIINCKK 527

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  851 ELDQALRESQRQVEALERAAREKEAMAKE----RAGLAVQLAAAEREGRTLSEETIRLRLEKEALESSLFDVQRQLAQLE 926
Cdd:pfam05483  528 QEERMLKQIENLEEKEMNLRDELESVREEfiqkGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKN 607

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  927 ARREQLEADSQALLLAKETLTGELAGLRQQVTATEekaaLDKELMTQKLVQAERETQASLREQRAAHEEDLQRLQREKEA 1006
Cdd:pfam05483  608 KNIEELHQENKALKKKGSAENKQLNAYEIKVNKLE----LELASAKQKFEEIIDNYQKEIEDKKISEEKLLEEVEKAKAI 683

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1007 AwrelqAERAQLQGQLQQEREELLARMEAEKEELSEEIAALQQERDEGLLLAESEKQQALSLKESEKTALSE---KLMGT 1083
Cdd:pfam05483  684 A-----DEAVKLQKEIDKRCQHKIAEMVALMEKHKHQYDKIIEERDSELGLYKNKEQEQSSAKAALEIELSNikaELLSL 758

                          570
                   ....*....|....*....
gi 1958776745 1084 RHSLAAISLEMERQKRDAQ 1102
Cdd:pfam05483  759 KKQLEIEKEEKEKLKMEAK 777
CHASE3 COG5278
Extracytoplasmic sensor domain CHASE3 (specificity unknown) [Signal transduction mechanisms];
570-996 6.63e-04

Extracytoplasmic sensor domain CHASE3 (specificity unknown) [Signal transduction mechanisms];


Pssm-ID: 444089 [Multi-domain]  Cd Length: 530  Bit Score: 44.51  E-value: 6.63e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  570 EQLQRLRDQTATSVQAQEDAQREAQRLRSANEILSREKGNLSHSLQVAQQQAEDLRQELEKLQAAQEELRRQHTQLEDQQ 649
Cdd:COG5278    104 EQQARLDELEALIDQWLAELEQVIALRRAGGLEAALALVRSGEGKALMDEIRARLLLLALALAALLLAAAALLLLLLALA 183

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  650 EDTVQEGARARRELERSHRQLEQLEVKRSGLTKELVEVREALSCAVLQRDVLQTEKAEVAEALTKAEAGRAQLELSVTKL 729
Cdd:COG5278    184 ALLALAELLLLALARALAALLLLLLLEAELAAAAALLAAAAALAALAALELLAALALALALLLAALLLALLAALALAALL 263

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  730 RAEEASLRDSLSKMSALNESLAQDKLELNRLIAQLEEEKAALLGRQQQAEHATSLAVEKQERLEQLRLEQEVERQGLEGS 809
Cdd:COG5278    264 AAALLALAALLLALAAAAALAAAAALELAAAEALALAELELELLLAAAAAAAAAAAAAAAALAALLALALATALAAAAAA 343

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  810 LCVAEQAREALGQQILVLRSERSHLQEQVAQLSRQLNGRDQELDQALRESQRQVEALERAAREKEAMAKERAGLAVQLAA 889
Cdd:COG5278    344 LALLAALLAEAAAAAAEEAEAAAEAAAAALAGLAEVEAEGAAEAVELEVLAIAAAAAAAAAEAAAAAAAAAAASAAEALE 423

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  890 AEREGRTLSEETIRLRLEKEALESSLFDVQRQLAQLEARREQLEADSQALLLAKETLTGELAGLRQQVTATEEKAALDKE 969
Cdd:COG5278    424 LAEALAEALALAEEEALALAAASSELAEAGAALALAAAEALAEELAAVAALAALAAAAAALAEAEAAAALAAAAALSLAL 503

                          410       420
                   ....*....|....*....|....*..
gi 1958776745  970 LMTQKLVQAERETQASLREQRAAHEED 996
Cdd:COG5278    504 ALAALLLAAAEAALAAALAAALASAEL 530
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
529-752 7.06e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 44.91  E-value: 7.06e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  529 ALHKRQLQVQDMRGRYEASQDLLGSVRKQLSDSEGERRGLEEQLQRLRDQTATSVQAQEDAQREAQRLRSANEilsrekg 608
Cdd:COG4913    665 SAEREIAELEAELERLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLE------- 737

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  609 nlshslQVAQQQAEDLRQELEKL--QAAQEELRRQ-HTQLEDQQEDTVQEGARARRELERSHRQ-LEQLEVKRSGLTKEL 684
Cdd:COG4913    738 ------AAEDLARLELRALLEERfaAALGDAVERElRENLEERIDALRARLNRAEEELERAMRAfNREWPAETADLDADL 811

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1958776745  685 VEVREALS-CAVLQRDVLQTEKAEVAEALTKAEagRAQLELSVTKLRAEEASLRDSLSKmsaLNESLAQ 752
Cdd:COG4913    812 ESLPEYLAlLDRLEEDGLPEYEERFKELLNENS--IEFVADLLSKLRRAIREIKERIDP---LNDSLKR 875
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 118-908 7.36e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 44.67  E-value: 7.36e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  118 ERLEQAVR-LETGELEAQEPRGLVRQSVELRRQLQEEqasyRRKLQAYQEGQQRQAQLVQRLQAKILQ-YKKQCSEMEKQ 195
Cdd:TIGR02169  170 RKKEKALEeLEEVEENIERLDLIIDEKRQQLERLRRE----REKAERYQALLKEKREYEGYELLKEKEaLERQKEAIERQ 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  196 LLERSTELEQQRLRDTEHSQDLDRALLRLEEEQQR-------------------SASLAQVNDMLREQLDQANLANQTLS 256
Cdd:TIGR02169  246 LASLEEELEKLTEEISELEKRLEEIEQLLEELNKKikdlgeeeqlrvkekigelEAEIASLERSIAEKERELEDAEERLA 325

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  257 EDICKVtSDWTRSCKELEQREATWRREEESFNAYFSSEHSRLLLLWRQVMGLRRMASEVK---MGTERDLLQLG---GEL 330
Cdd:TIGR02169  326 KLEAEI-DKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRdelKDYREKLEKLKreiNEL 404

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  331 VRTSRAVQEVGLGLSASLQRAESRAEAALEKQKLLQAQLEEQLRAKLLREKDLAQLQVQSDLDKADLSARVTELALSVEH 410
Cdd:TIGR02169  405 KRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKE 484

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  411 LQNQNTEKDQVNRTLSDKLEALESLRLQEqtTLDTEDGEGLQQTLRDLAQ-----AALSDTESGVQLSNSERTADTSDGS 485
Cdd:TIGR02169  485 LSKLQRELAEAEAQARASEERVRGGRAVE--EVLKASIQGVHGTVAQLGSvgeryATAIEVAAGNRLNNVVVEDDAVAKE 562

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  486 FRGLFGQRTPTPPRHSSPGRGRSPRRGLSPACSDSSTLTLIHSALHKRQLQ------------VQDMrgryEASQDLLGS 553
Cdd:TIGR02169  563 AIELLKRRKAGRATFLPLNKMRDERRDLSILSEDGVIGFAVDLVEFDPKYEpafkyvfgdtlvVEDI----EAARRLMGK 638

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  554 VR-------------------KQLSDSEGERRGLEEQLQRLRDQtatsvqaQEDAQREAQRLRSANEILSREKGNLSHSL 614
Cdd:TIGR02169  639 YRmvtlegelfeksgamtggsRAPRGGILFSRSEPAELQRLRER-------LEGLKRELSSLQSELRRIENRLDELSQEL 711

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  615 QVAQQQAEDLRQELEKLQAAQEELRRQHTQLEDQQEDTVQEGARARRELERSHRQLEQLEVKRSGLTKELVEVREALSCA 694
Cdd:TIGR02169  712 SDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHS 791

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  695 VLQRdvLQTEKAEVAEALTKAEAGRAQLELSVTKLRAEEASLRDSLSKMSALNESLAQDKLELNRLIAQLEEEKAALLGR 774
Cdd:TIGR02169  792 RIPE--IQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEE 869

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  775 QQQAEHATSLAVEKQERLEQLRLEQEVERQGLEGSLCVAEQAREALGQQILVLRSERSHLQEQVAQLSRQLnGRDQE--- 851
Cdd:TIGR02169  870 LEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPK-GEDEEipe 948

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1958776745  852 -------LDQALRESQRQVEALE----RAAREKEAMAKERAGLAVQLAAAEREGRTLSEETIRLRLEK 908
Cdd:TIGR02169  949 eelsledVQAELQRVEEEIRALEpvnmLAIQEYEEVLKRLDELKEKRAKLEEERKAILERIEEYEKKK 1016
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1722-1934 7.76e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.98  E-value: 7.76e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1722 VQSLTDALAQSSASLTSSQDKNLYLQKALSTCEHDRQVLQERLDAARQALSEARRQSSSLGEQVQTLRGELANLELQRGD 1801
Cdd:COG4942     15 AAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAE 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1802 AEGQLQQLQQVLRQR------------------QEGEAVALRSVQKLQEERRLLQERLGSLQRALAQLEAEKRELERSAL 1863
Cdd:COG4942     95 LRAELEAQKEELAELlralyrlgrqpplalllsPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERA 174

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1958776745 1864 QLDKDRVALRKTLDKVEREKLRSHEDTLRLNAERGRLDRTLTGAELDLAEAQQQIQHLEAQVVEVLERNHS 1934
Cdd:COG4942    175 ELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 898-1403 8.50e-04

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 44.33  E-value: 8.50e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  898 SEETIRLRLEKEALESSLFDVQRQLAQLEARREQLEADSQALLLAKETLTGELAGLRQQVTATEEKAALDKELMTQKLVQ 977
Cdd:pfam05483  168 AEKTKKYEYEREETRQVYMDLNNNIEKMILAFEELRVQAENARLEMHFKLKEDHEKIQHLEEEYKKEINDKEKQVSLLLI 247

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  978 AERETQASLREQRAAHEEDLQRLQR--EKEAAWRELQAERAQLQGQLQQEREELLARMEAEKEELSEEIAALQQERDEGL 1055
Cdd:pfam05483  248 QITEKENKMKDLTFLLEESRDKANQleEKTKLQDENLKELIEKKDHLTKELEDIKMSLQRSMSTQKALEEDLQIATKTIC 327

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1056 LLAESEKQQalsLKESEKTALSEKLMGTRhsLAAISLEMERQKRDAQSRQEQDRNTVNALTSELRDLRAQLEEATAAHAQ 1135
Cdd:pfam05483  328 QLTEEKEAQ---MEELNKAKAAHSFVVTE--FEATTCSLEELLRTEQQRLEKNEDQLKIITMELQKKSSELEEMTKFKNN 402

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1136 QVKELQEQTGNLGrQREACMREAEELRTQLRLLEDTRDGLRRELLEAQRKVRDSQDSSEAHRQEASELRRSLSEGTKERE 1215
Cdd:pfam05483  403 KEVELEELKKILA-EDEKLLDEKKQFEKIAEELKGKEQELIFLLQAREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELE 481

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1216 ALRRSNEELRTAVKKAESERISLKLANEDKEQKLALLEEARMSVAKEAGELRASLQEVERSRLEARRELQELRRQMKtld 1295
Cdd:pfam05483  482 KEKLKNIELTAHCDKLLLENKELTQEASDMTLELKKHQEDIINCKKQEERMLKQIENLEEKEMNLRDELESVREEFI--- 558

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1296 sdngrlgRELADLQSRLALGERTEKESRREVLGLRQKVLKGESSLEALKQELQGSQRKLQEQEAEFRArergllgsLEEA 1375
Cdd:pfam05483  559 -------QKGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKA--------LKKK 623

                          490       500       510
                   ....*....|....*....|....*....|..
gi 1958776745 1376 RGAEKKLLDS----ARSLELRLEGVRAETSEL 1403
Cdd:pfam05483  624 GSAENKQLNAyeikVNKLELELASAKQKFEEI 655
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 870-1444 9.42e-04

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 44.58  E-value: 9.42e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  870 AREKEAMAKERAGLAVQLAAAEREGRTLSEETIRLRLEKEALESSLFDVQRQLAQLEARREQLEADSQALLLAKETLTGE 949
Cdd:pfam02463  165 SRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQE 244

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  950 LAGLRQQVTAT---EEKAALDKELMTQKLVQAERETQASLREQRAAHEEDLQRLQREKEAAWRELQAERAQLQGQLQQER 1026
Cdd:pfam02463  245 LLRDEQEEIESskqEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKK 324

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1027 EELLARMEAEKEELSEEIAALQQERDEGLLLAESEKQQALSLKESEKtalSEKLMGTRHSLAAISLEMERQKRDAQSRQE 1106
Cdd:pfam02463  325 KAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQL---EEELLAKKKLESERLSSAAKLKEEELELKS 401

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1107 QDRNTVNALTSELRDLRAQLEEATAAHAQQVKELQEQTGNLGRQREACMREAEELRTQLRLLEDTRDGLRRELLEAQRKV 1186
Cdd:pfam02463  402 EEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVK 481

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1187 RDSQDSSEAHRQEASELRRSLSEGTKEREALRRSNEELRTAVKKAESERISLKLANEDKE--QKLALLEEARMSVAKEAG 1264
Cdd:pfam02463  482 LQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYkvAISTAVIVEVSATADEVE 561

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1265 ELRASLQEVERSRLEARRELQELR-RQMKTLDSDNGRLGRELADLQSRLALGERTEKESRREVLGLRQKVLKGESSLEAL 1343
Cdd:pfam02463  562 ERQKLVRALTELPLGARKLRLLIPkLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESA 641

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1344 KQELQGSQRKLQEQEAEFRARERGLLGSLEEARGAEKKLLDSARSLELRLEGVRAETSELGLRLSAAEGRAQGLEVELAR 1423
Cdd:pfam02463  642 KAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEE 721

                          570       580
                   ....*....|....*....|.
gi 1958776745 1424 VEAQRRVAEAQLGGLRSALRR 1444
Cdd:pfam02463  722 LLADRVQEAQDKINEELKLLK 742
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 1157-1366 1.06e-03

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 44.27  E-value: 1.06e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1157 EAEELRTQLRLLEDTRDGLRRELLEAQRKVRDSQDSSEAHRQEASELRRSLSEGTKEREALRRSNEELRTAVKkaeseRI 1236
Cdd:PRK10929    24 DEKQITQELEQAKAAKTPAQAEIVEALQSALNWLEERKGSLERAKQYQQVIDNFPKLSAELRQQLNNERDEPR-----SV 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1237 SLKLANEDKEQKL-----ALLEEARMSVAKE--AGELRASLQEVERSRLEARRELQELRRQMKTLDSDNGRLGR-ELADL 1308
Cdd:PRK10929    99 PPNMSTDALEQEIlqvssQLLEKSRQAQQEQdrAREISDSLSQLPQQQTEARRQLNEIERRLQTLGTPNTPLAQaQLTAL 178

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1958776745 1309 QSRLALGERTEKE---------SRREVLGLRQKVLKGESS-LEALKQELQGSQRKLQEQEAEfRARER 1366
Cdd:PRK10929   179 QAESAALKALVDElelaqlsanNRQELARLRSELAKKRSQqLDAYLQALRNQLNSQRQREAE-RALES 245
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 647-906 1.06e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.60  E-value: 1.06e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  647 DQQEDTVQEGARARRELERSHRQLEQLEVKRSGLTKELVEVREALSCAVLQRDVLQTEKAEVAEALTKAEAGRAQLELSV 726
Cdd:COG4942     20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  727 TKLRAEEASLRDSLSKMSALNeslaqdklelnrliaqleeeKAALLGRQQQAEHAtslaVEKQERLEQLRLEQEVERQGL 806
Cdd:COG4942    100 EAQKEELAELLRALYRLGRQP--------------------PLALLLSPEDFLDA----VRRLQYLKYLAPARREQAEEL 155

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  807 EGSLCVAEQAREALGQQILVLRSERSHLQEQVAQLSRQLNGRDQELDQALRESQRQVEALERAAREKEAMAKERAGLAVQ 886
Cdd:COG4942    156 RADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAE 235

                          250       260
                   ....*....|....*....|
gi 1958776745  887 LAAAEREGRTLSEETIRLRL 906
Cdd:COG4942    236 AAAAAERTPAAGFAALKGKL 255
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1640-1899 1.17e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.60  E-value: 1.17e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1640 ASESRSIKLELQRRALEGELQRSRLGLGDREAHAQALQDRVDSLQRQVADSEVKAGTLQLTVERLSGALAKVEESEGTLR 1719
Cdd:COG4942     17 AQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELR 96

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1720 SKVQSLTDALAQSSASLTSSQDKNlYLQKALSTCEHDRQVlqeRLDAARQALSEARRqssslgEQVQTLRGELANLELQR 1799
Cdd:COG4942     97 AELEAQKEELAELLRALYRLGRQP-PLALLLSPEDFLDAV---RRLQYLKYLAPARR------EQAEELRADLAELAALR 166

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1800 GDAEGQLQQLQQVLrqrqegeavalrsvQKLQEERRLLQERLGSLQRALAQLEAEKRELERSALQLDKDRVALRKTLDKV 1879
Cdd:COG4942    167 AELEAERAELEALL--------------AELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARL 232

                          250       260
                   ....*....|....*....|
gi 1958776745 1880 EREKLRSHEDTLRLNAERGR 1899
Cdd:COG4942    233 EAEAAAAAERTPAAGFAALK 252
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 528-725 1.23e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.60  E-value: 1.23e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  528 SALHKRQLQVQDMRGRYEASQDLLGSVRKQLSDSEGERRGLEEQLQRLRDQTATSVQAqedAQREAQRLRSANEILSREK 607
Cdd:COG4942     55 KQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAELLRA---LYRLGRQPPLALLLSPEDF 131

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  608 GNLSHSLQVAQQQAEDLRQELEKLQAAQEELRRQHTQLEDQQEDTvqegARARRELERSHRQLEQLEVKRSGLTKELVEV 687
Cdd:COG4942    132 LDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAEL----EALLAELEEERAALEALKAERQKLLARLEKE 207

                          170       180       190
                   ....*....|....*....|....*....|....*...
gi 1958776745  688 REALSCAVLQRDVLQTEKAEVAEALTKAEAGRAQLELS 725
Cdd:COG4942    208 LAELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 553-847 1.23e-03

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 43.86  E-value: 1.23e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  553 SVRKQLSDSEGERRGLEEQLQRLRDQTATSVQAQEDAQREAQRLRSANEILSREKGNLSHSLQVAQQQAEDLRQELEKLQ 632
Cdd:TIGR04523  346 QLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLE 425

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  633 AAQEELRRQHTQLEDQQEDTVQEGARARRELERSHRQLEQLEVKRSGLTKE-------LVEVREALSCAVLQRDVLQTEK 705
Cdd:TIGR04523  426 KEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSinkikqnLEQKQKELKSKEKELKKLNEEK 505

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  706 AEVAEALTKAEAGRAQLELSVTKLRAE----EASLRDSLSKMSALNESLAQDKLE-----LNRLIAQLEEEKAALLGRQQ 776
Cdd:TIGR04523  506 KELEEKVKDLTKKISSLKEKIEKLESEkkekESKISDLEDELNKDDFELKKENLEkeideKNKEIEELKQTQKSLKKKQE 585

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1958776745  777 QA-EHATSLAVEKQERLEQLrLEQEVERQGLEGSLCVAEQAREALGQQILVLRSERSHLQEQVAQLSRQLNG 847
Cdd:TIGR04523  586 EKqELIDQKEKEKKDLIKEI-EEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKE 656
PRK09039 PRK09039
peptidoglycan -binding protein;
1702-1796 1.32e-03

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 43.03  E-value: 1.32e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1702 ERLSGALAKVEESEGTLRSKVQSLTDALAQSSASLTSSQDKNLYLQKALSTCEHDRQVLQER-------LDAARQALSEA 1774
Cdd:PRK09039    56 DRLNSQIAELADLLSLERQGNQDLQDSVANLRASLSAAEAERSRLQALLAELAGAGAAAEGRagelaqeLDSEKQVSARA 135

                           90       100
                   ....*....|....*....|..
gi 1958776745 1775 RRQSSSLGEQVQTLRGELANLE 1796
Cdd:PRK09039   136 LAQVELLNQQIAALRRQLAALE 157
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1584-1939 1.39e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 43.90  E-value: 1.39e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1584 RSRRECRATLDQMAVLERSLQATESELRASQEKVNKMKATEVKLESDKRRLKEVldasesRSIKLELQRRALEGELQRSR 1663
Cdd:TIGR02169  170 RKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAERYQALLKEKREY------EGYELLKEKEALERQKEAIE 243

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1664 LGLGDREAHAQALQDRVDSLQRQVADSEVKAGTLQLTVERLSgalakvEESEGTLRSKVQSLTDALAQSSASLTSSQDKN 1743
Cdd:TIGR02169  244 RQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLG------EEEQLRVKEKIGELEAEIASLERSIAEKEREL 317

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1744 LYLQKALSTCEHDRQVLQERLDAARQALSEARRQSSSLGEQVQTLRGELANLELQRGDAEGQLqqlqqvlrqrqegeAVA 1823
Cdd:TIGR02169  318 EDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEF--------------AET 383

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1824 LRSVQKLQEERRLLQERLGSLQRALAQLEAEKREL--------------ERSALQLDKDRVALRKTLDKVEREKLRSHED 1889
Cdd:TIGR02169  384 RDELKDYREKLEKLKREINELKRELDRLQEELQRLseeladlnaaiagiEAKINELEEEKEDKALEIKKQEWKLEQLAAD 463

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1890 TLRLNAERGRLDRTLTGAELDLAEAQQQIQHLEAQVVEVLERNHSPVQVE 1939
Cdd:TIGR02169  464 LSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVE 513
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 1025-1663 1.79e-03

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 43.56  E-value: 1.79e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1025 EREELLARMEAEKEELSEEIAALQQERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRHslaaISLEMERQKRDAQSR 1104
Cdd:pfam05483   71 ENSEGLSRLYSKLYKEAEKIKKWKVSIEAELKQKENKLQENRKIIEAQRKAIQELQFENEK----VSLKLEEEIQENKDL 146

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1105 QEQDrNTVNALTSELRDLRAQLEEATAAHAQQVKELQEQTGNLGRQREACMREAEELRTQLrllEDTRDGLRRELLEAQR 1184
Cdd:pfam05483  147 IKEN-NATRHLCNLLKETCARSAEKTKKYEYEREETRQVYMDLNNNIEKMILAFEELRVQA---ENARLEMHFKLKEDHE 222

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1185 KVR----DSQDSSEAHRQEASELRRSLSEGTKEREALRRSNEELRTAVKKAES----ERISLKLANEDKEQKLALLEEAR 1256
Cdd:pfam05483  223 KIQhleeEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKANQLEEktklQDENLKELIEKKDHLTKELEDIK 302

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1257 MSVAKEAGELRASLQEVERSRLEARRELQELRRQMKTLDSDNGRLGRELADLQSRLALGERTEKESRrevlglrQKVLKG 1336
Cdd:pfam05483  303 MSLQRSMSTQKALEEDLQIATKTICQLTEEKEAQMEELNKAKAAHSFVVTEFEATTCSLEELLRTEQ-------QRLEKN 375

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1337 ESSLEALKQELQGSQRKLQEQeAEFRARERGLLGSLEEARGAEKKLLDSARSLELRLEGVRAETSELGLRLSAAEGRAQG 1416
Cdd:pfam05483  376 EDQLKIITMELQKKSSELEEM-TKFKNNKEVELEELKKILAEDEKLLDEKKQFEKIAEELKGKEQELIFLLQAREKEIHD 454

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1417 LEVELARVEAQRRVAEAQLGGLRSALRRglglgrvssSPAREAPAGGSGDGLSspspLEYSPRSQPPSPGPVASPAPPDl 1496
Cdd:pfam05483  455 LEIQLTAIKTSEEHYLKEVEDLKTELEK---------EKLKNIELTAHCDKLL----LENKELTQEASDMTLELKKHQE- 520

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1497 DPEAVRDALRDFLQELRSAQRE----RDELRVQTSTLSQQLAEMEAERDHAASRAKQLQKAVAESEEAWRSADRRLSGAQ 1572
Cdd:pfam05483  521 DIINCKKQEERMLKQIENLEEKemnlRDELESVREEFIQKGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLK 600

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1573 AELALQEESVRRSRRECRAtldqmavLERSLQATESELRASQEKVNKMkatEVKLESDKRRLKEVLDASESRSIKLELQR 1652
Cdd:pfam05483  601 KQIENKNKNIEELHQENKA-------LKKKGSAENKQLNAYEIKVNKL---ELELASAKQKFEEIIDNYQKEIEDKKISE 670

                          650
                   ....*....|.
gi 1958776745 1653 RALEGELQRSR 1663
Cdd:pfam05483  671 EKLLEEVEKAK 681
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 525-1326 1.90e-03

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 43.40  E-value: 1.90e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  525 LIHSALHKRQlQVQDMRGRYEASQDLLGSVRKQLSDSEGERRGLEEQLQRLRDQTA---TSVQAQEDAQREAQRLRSANE 601
Cdd:COG3096    283 LSERALELRR-ELFGARRQLAEEQYRLVEMARELEELSARESDLEQDYQAASDHLNlvqTALRQQEKIERYQEDLEELTE 361

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  602 ilsrekgNLSHSLQVAQQQAEDLRQELEKLQAAQEELRRQHTQLEDQQE--DTVQEGA----RARRELERSHRQLEQLEV 675
Cdd:COG3096    362 -------RLEEQEEVVEEAAEQLAEAEARLEAAEEEVDSLKSQLADYQQalDVQQTRAiqyqQAVQALEKARALCGLPDL 434

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  676 KRSGLTKELVEVREALSCAVLQRDVLQTEKAEVAEALTKAEAGRAQLELSVTKLRAEEAS------LRDSLSkMSALNES 749
Cdd:COG3096    435 TPENAEDYLAAFRAKEQQATEEVLELEQKLSVADAARRQFEKAYELVCKIAGEVERSQAWqtarelLRRYRS-QQALAQR 513

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  750 LAQDKLELNRLIAQLEEEKAAllgRQQQAEHATSLA--VEKQERLEQLRLEQEVERQGLEgslcvaEQAREAlGQQILVL 827
Cdd:COG3096    514 LQQLRAQLAELEQRLRQQQNA---ERLLEEFCQRIGqqLDAAEELEELLAELEAQLEELE------EQAAEA-VEQRSEL 583

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  828 RSERSHLQEQVAQLSRQ----------LNGRDQELDQALRESQRQVEALERAAREKEAMAKERAGLAVQLAAAEREGRTL 897
Cdd:COG3096    584 RQQLEQLRARIKELAARapawlaaqdaLERLREQSGEALADSQEVTAAMQQLLEREREATVERDELAARKQALESQIERL 663

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  898 S----EETIRLRLEKEA----LESSLFD----------------------------VQRQLAQLEARREQL---EADSQA 938
Cdd:COG3096    664 SqpggAEDPRLLALAERlggvLLSEIYDdvtledapyfsalygparhaivvpdlsaVKEQLAGLEDCPEDLyliEGDPDS 743

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  939 ----LLLAKETLTGELAGLRQQV--------------TATEEKAAldkELMTQKLVQAERETQASLREQR---------- 990
Cdd:COG3096    744 fddsVFDAEELEDAVVVKLSDRQwrysrfpevplfgrAAREKRLE---ELRAERDELAEQYAKASFDVQKlqrlhqafsq 820

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  991 -------AAHEEDLQRLQREKEAAWRELQAERAQLQGQLQQEReellarmeaekeelseeiaalqqerdeglllaesekQ 1063
Cdd:COG3096    821 fvgghlaVAFAPDPEAELAALRQRRSELERELAQHRAQEQQLR------------------------------------Q 864

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1064 QALSLKESekTALSEKLMGTRHSLAAISLemerqkrdaqsrqeQDRntvnaltseLRDLRAQLEEATAA------HAQQV 1137
Cdd:COG3096    865 QLDQLKEQ--LQLLNKLLPQANLLADETL--------------ADR---------LEELREELDAAQEAqafiqqHGKAL 919

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1138 KELQEQTGNLGRQREacmrEAEELRTQLRLLEDTRDGLRRELLE----AQRKVRDSQDSSEAHRQEASELRRSLSEGTKE 1213
Cdd:COG3096    920 AQLEPLVAVLQSDPE----QFEQLQADYLQAKEQQRRLKQQIFAlsevVQRRPHFSYEDAVGLLGENSDLNEKLRARLEQ 995

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1214 RE-ALRRSNEELRTAVKKAES---ERISLKLANEDKEQKLALLEEaRMsvakEAGELRASLQEVERSRLEARR---ELQE 1286
Cdd:COG3096    996 AEeARREAREQLRQAQAQYSQynqVLASLKSSRDAKQQTLQELEQ-EL----EELGVQADAEAEERARIRRDElheELSQ 1070

                          890       900       910       920
                   ....*....|....*....|....*....|....*....|
gi 1958776745 1287 LRRQMKTLDSDNGRLGRELADLQSRLALGERTEKESRREV 1326
Cdd:COG3096   1071 NRSRRSQLEKQLTRCEAEMDSLQKRLRKAERDYKQEREQV 1110
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1270-1895 2.13e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 43.13  E-value: 2.13e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1270 LQEVERSRLEARRELQELRRQMKTLDSDNGRLGRELADLQSRLALGERTEKESRREVLGLRQKVLKgessLEALKQELQG 1349
Cdd:PRK03918   167 LGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKE----LEELKEEIEE 242

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1350 SQRKLQEQEAEFRARE---RGLLGSLEEARGAEKKLLDSARSLElRLEGVRAETSELGLRLSAAEGRAQGLEVELARVEA 1426
Cdd:PRK03918   243 LEKELESLEGSKRKLEekiRELEERIEELKKEIEELEEKVKELK-ELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEE 321

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1427 QRRVAEAQLGGLRSALRRGLGLGRVSSSPAREApaggsgdGLSSPSPLEYSPRSQPPSPGPVASPAPPDLDPEAVRdalr 1506
Cdd:PRK03918   322 EINGIEERIKELEEKEERLEELKKKLKELEKRL-------EELEERHELYEEAKAKKEELERLKKRLTGLTPEKLE---- 390

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1507 dflQELRSAQRERDELRVQTSTLSQQLAEMEaerdhaaSRAKQLQKAVaeseEAWRSADRRLSGAQAElaLQEESVRRSR 1586
Cdd:PRK03918   391 ---KELEELEKAKEEIEEEISKITARIGELK-------KEIKELKKAI----EELKKAKGKCPVCGRE--LTEEHRKELL 454

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1587 RECRATLDQMAVLERSLQATESELRASQEKVNKmkatEVKLESDKRRLKEVLDasESRSIKLELQRRALEgELQRSRLGL 1666
Cdd:PRK03918   455 EEYTAELKRIEKELKEIEEKERKLRKELRELEK----VLKKESELIKLKELAE--QLKELEEKLKKYNLE-ELEKKAEEY 527

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1667 GDREAHAQALQDRVDSLQRQVADSEVKAGTLQLTVERLSGALAKVEESEGTLRSKVQSLTDALAQSSASLTSSQDKNLYL 1746
Cdd:PRK03918   528 EKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKELEPFYNEYLEL 607

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1747 QKAlstcEHDRQVLQERLDAARQALSEARRQSSSLGEQVQTLRGELANLELQRGDAEgqlqqlqqvlRQRQEGEAVALRS 1826
Cdd:PRK03918   608 KDA----EKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEE----------YEELREEYLELSR 673

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1958776745 1827 -VQKLQEERRLLQERLGSLQRALAQLEAEKRELERSALQLDKdrvaLRKTLDKVE--REKLRSHEDTLRLNA 1895
Cdd:PRK03918   674 eLAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKELEK----LEKALERVEelREKVKKYKALLKERA 741
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 518-1029 2.90e-03

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 42.90  E-value: 2.90e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  518 SDSSTLTLIHSALHKRQLQVQDMRGRYEASQDLlgSVRKQLSDSEGERRGLEEQLQRLRDQTATSVQAQEDAQREA--QR 595
Cdd:pfam12128  354 SELENLEERLKALTGKHQDVTAKYNRRRSKIKE--QNNRDIAGIKDKLAKIREARDRQLAVAEDDLQALESELREQleAG 431

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  596 LRSANEILSREKGNLSH-SLQVAQQQAE-----DLRQELEKLQAAQEELRRQHTQLEDQQEDTVQegARARRE-LERSHR 668
Cdd:pfam12128  432 KLEFNEEEYRLKSRLGElKLRLNQATATpelllQLENFDERIERAREEQEAANAEVERLQSELRQ--ARKRRDqASEALR 509

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  669 QLEQLEVKRSGLTKELVEVREALSCAVLQrdVLQTEKAEVAEALTKAeAGRAQLELSVTKLRAEEASLRDSLSKMSAlne 748
Cdd:pfam12128  510 QASRRLEERQSALDELELQLFPQAGTLLH--FLRKEAPDWEQSIGKV-ISPELLHRTDLDPEVWDGSVGGELNLYGV--- 583

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  749 SLAQDKLELNRLIAQLEE--EKAALLGRQQQAEHATSLAVEKQerLEQLRLEQEVERQGLEGSLCVAEQAREALGQQILV 826
Cdd:pfam12128  584 KLDLKRIDVPEWAASEEElrERLDKAEEALQSAREKQAAAEEQ--LVQANGELEKASREETFARTALKNARLDLRRLFDE 661

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  827 LRSERSHLQEQVAQLSRQLNGR----DQELDQALRESQRQVEALERAARE-----------------------KEAMAKE 879
Cdd:pfam12128  662 KQSEKDKKNKALAERKDSANERlnslEAQLKQLDKKHQAWLEEQKEQKREartekqaywqvvegaldaqlallKAAIAAR 741

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  880 RAGLAVQLAAAERE------GRTLSEETI-RLRLEKEALESSLFDVQRQLAQLEA----RREQLEADSQALLLAKETLTG 948
Cdd:pfam12128  742 RSGAKAELKALETWykrdlaSLGVDPDVIaKLKREIRTLERKIERIAVRRQEVLRyfdwYQETWLQRRPRLATQLSNIER 821

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  949 ELAGLRQQVTATEEKAALD-KELMTQK--LVQAERETQASLREQRA-----------AHEEDLQRLQREKEAAWRELQAE 1014
Cdd:pfam12128  822 AISELQQQLARLIADTKLRrAKLEMERkaSEKQQVRLSENLRGLRCemsklatlkedANSEQAQGSIGERLAQLEDLKLK 901

                          570
                   ....*....|....*
gi 1958776745 1015 RAQLQGQLQQEREEL 1029
Cdd:pfam12128  902 RDYLSESVKKYVEHF 916
mukB PRK04863
chromosome partition protein MukB;
850-1368 3.02e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 42.64  E-value: 3.02e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  850 QELDQALRESQRQVEALERAARE----KEAMAKERAGLAVQLAAAEREGRTLSEETIRLRLEK-------EALESSLFDV 918
Cdd:PRK04863   233 QDMEAALRENRMTLEAIRVTQSDrdlfKHLITESTNYVAADYMRHANERRVHLEEALELRRELytsrrqlAAEQYRLVEM 312

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  919 QRQLAQLEARREQLEADSQAlllAKETLTGELAGLRQQvtATEEKAALDKELMTQKLvqaerETQASLREQraAHEEdLQ 998
Cdd:PRK04863   313 ARELAELNEAESDLEQDYQA---ASDHLNLVQTALRQQ--EKIERYQADLEELEERL-----EEQNEVVEE--ADEQ-QE 379

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  999 RLQREKEAAwrelQAERAQLQGQLQ--QEREELLARMeaekeelseeiaALQQerdeglllaesekQQALSLKESEKTAL 1076
Cdd:PRK04863   380 ENEARAEAA----EEEVDELKSQLAdyQQALDVQQTR------------AIQY-------------QQAVQALERAKQLC 430

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1077 SeklmgtrhsLAAISLEmerqkrDAQSRQEQDRNTVNALTSELRDLRAQLEEATAAHAQQVKELQEQTGNLGR-QREACM 1155
Cdd:PRK04863   431 G---------LPDLTAD------NAEDWLEEFQAKEQEATEELLSLEQKLSVAQAAHSQFEQAYQLVRKIAGEvSRSEAW 495

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1156 REAeelrtqlrlledtrdglrRELLEAQRKVRDSQDSSEAHRQEASELRRSLSEgtkerealRRSNEELRTAVKKaeseR 1235
Cdd:PRK04863   496 DVA------------------RELLRRLREQRHLAEQLQQLRMRLSELEQRLRQ--------QQRAERLLAEFCK----R 545

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1236 ISLKLANEDKEQKLALLEEARMSvakeagELRASLQEVERSRLEARRELQELRRQMKTLDSdngrLGRELADLQSRLA-L 1314
Cdd:PRK04863   546 LGKNLDDEDELEQLQEELEARLE------SLSESVSEARERRMALRQQLEQLQARIQRLAA----RAPAWLAAQDALArL 615

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1958776745 1315 GERT--EKESRREVLGLRQKVLKGESSL-------EALKQELQGSQRKLQEQEAEFRARERGL 1368
Cdd:PRK04863   616 REQSgeEFEDSQDVTEYMQQLLERERELtverdelAARKQALDEEIERLSQPGGSEDPRLNAL 678
COG5281 COG5281
Phage-related minor tail protein [Mobilome: prophages, transposons];
1045-1454 3.36e-03

Phage-related minor tail protein [Mobilome: prophages, transposons];


Pssm-ID: 444092 [Multi-domain]  Cd Length: 603  Bit Score: 42.29  E-value: 3.36e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1045 AALQQERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLAAISLEMERQKRDAQSRQEQDRNTVNALTSELRDLRA 1124
Cdd:COG5281     17 AAASAAAAAAAAALAAAAAAAAAAAGLAAAAAAAAAASLAAAAAAAALAAAAAAAAAAAAADALAAALAEDAAAAAAAAE 96

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1125 QLEEATAAHAQQVKELQEQTGNLGRQREACMREAEELRTQLRLLEDTRDGLRRELLEAQRKVRDSQDSSE-AHRQEASEL 1203
Cdd:COG5281     97 AALAALAAAALALAAAALAEAALAAAAAAAAAAAAAAAAAAAAAAAAAEAAKAAAAAAAAAALAAAAAAAaAAAAAAAAA 176

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1204 RRSLSEGTKEREALRRSNEELRTAVKKAESERISLKLANEDKEQKLALLEEARMsVAKEAGELRASLQEVERSRLEARRE 1283
Cdd:COG5281    177 AALAAASAAAAAAAAKAAAEAAAEAAAAAEAAAAAAAAAAEAAAAEAQALAAAA-LAEQAALAAASAAAQALAALAAAAA 255

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1284 LQELRRQMKTLDSDNGRLGRELADLQSRLALGERTEKESRREVLGLRQKVLKGESSLEALKQELQGSQRKLQEQEAEFRA 1363
Cdd:COG5281    256 AAALALAAAAELALTAQAEAAAAAAAAAAAAAQAAEAAAAAAEAQALAAAAAAAAAQLAAAAAAAAQALRAAAQALAALA 335

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1364 RERGLLGSLEEARGAEKKLLDSARSLELRLEGVRAETSELGLRLSAAEGRAQGL----EVELARVEAQRRVAEAQLGGLR 1439
Cdd:COG5281    336 QRALAAAALAAAAQEAALAAAAAALQAALEAAAAAAAAELAAAGDWAAGAKAALaeyaDSATNVAAQVAQAATSAFSGLT 415

                          410
                   ....*....|....*
gi 1958776745 1440 SALRRGLGLGRVSSS 1454
Cdd:COG5281    416 DALAGAVTTGKLLFD 430
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 377-915 3.95e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 42.41  E-value: 3.95e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  377 LLREKDLAQLQVQ--SDLDKADLSARVTELALSVEHLQNQNTEKDQVNrTLSDKLEALESL--RLQEQTTLDTEDGEGLQ 452
Cdd:pfam15921  417 LRRELDDRNMEVQrlEALLKAMKSECQGQMERQMAAIQGKNESLEKVS-SLTAQLESTKEMlrKVVEELTAKKMTLESSE 495

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  453 QTLRDLAqAALSDTESGVQLSNSERTADTSDGSFRGLFGQRTPTPPRHSSPGRGRSPRRGLSPACSDSstltlIHSALHK 532
Cdd:pfam15921  496 RTVSDLT-ASLQEKERAIEATNAEITKLRSRVDLKLQELQHLKNEGDHLRNVQTECEALKLQMAEKDK-----VIEILRQ 569

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  533 RQLQVQDMRGRYEASQDLLGSVRKQLSDSEGERRGLEEQLQRLRDQTATSVQAQE----DAQREAQRLRSANEILSREKG 608
Cdd:pfam15921  570 QIENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEFKILKDKKDAKIRELEarvsDLELEKVKLVNAGSERLRAVK 649

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  609 NLSHSLQVAQQQAEDLRQELEKLQAAQEELRRQHTQLEDQQEDTVQ----EGARARRELERSHRQLEQLEVKRSGLTKEL 684
Cdd:pfam15921  650 DIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNklkmQLKSAQSELEQTRNTLKSMEGSDGHAMKVA 729

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  685 VEVREALSCAVLQRDVLQTEKAEVAEALTKAEAGRAQLELSVTKLRAEEASLRDSLSKMSALNESLAQDKLELNRLIAQL 764
Cdd:pfam15921  730 MGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANM 809

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  765 EE--EKAALlgrqQQAEHATSLAVEKQERLeQLRLEQEVERQGLEGSlcvAEQAREALGQQILVLRS-ERSHLQEQVAQL 841
Cdd:pfam15921  810 EValDKASL----QFAECQDIIQRQEQESV-RLKLQHTLDVKELQGP---GYTSNSSMKPRLLQPASfTRTHSNVPSSQS 881

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1958776745  842 SRQLNGRDQELDQALRESqrQVEALERAAREKEAMAKERAglAVQLAAAEREGRTLSEETIRLRLEKEALESSL 915
Cdd:pfam15921  882 TASFLSHHSRKTNALKED--PTRDLKQLLQELRSVINEEP--TVQLSKAEDKGRAPSLGALDDRVRDCIIESSL 951
PRK09039 PRK09039
peptidoglycan -binding protein;
838-967 3.98e-03

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 41.88  E-value: 3.98e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  838 VAQ--LSRQLNGRDQELDQALRESQRQVEALERAAREKEAMAKERAGLAVQLAAAEREGRtlseetiRLRLEKEALESSL 915
Cdd:PRK09039    39 VAQffLSREISGKDSALDRLNSQIAELADLLSLERQGNQDLQDSVANLRASLSAAEAERS-------RLQALLAELAGAG 111

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1958776745  916 FDVQRQLAQLEARREQLEADSQALLLAKETLTGELAGLRQQVTATEekAALD 967
Cdd:PRK09039   112 AAAEGRAGELAQELDSEKQVSARALAQVELLNQQIAALRRQLAALE--AALD 161
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
787-1146 4.10e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 41.81  E-value: 4.10e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  787 EKQERLEQLRLEQEVERQGLEGSLCVAEQAREALGQQILVLRSERSHLQEQVAQLSRQLNGRDQELDQALRESQRQVEAL 866
Cdd:COG4372     10 KARLSLFGLRPKTGILIAALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQL 89

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  867 ERAAREKEAMAKERAGLAVQLAAAEREGRTLSEETIRLRLEKEALESSLFDVQRQLAQLEARREQLEADSQALLLAKETL 946
Cdd:COG4372     90 QAAQAELAQAQEELESLQEEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAAL 169

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  947 TGELAGLRQQvTATEEKAALDKELMTQKLVQAERETQASLREQRAAhEEDLQRLQREKEAAWRELQAERAQLQGQLQQER 1026
Cdd:COG4372    170 EQELQALSEA-EAEQALDELLKEANRNAEKEEELAEAEKLIESLPR-ELAEELLEAKDSLEAKLGLALSALLDALELEED 247

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1027 EELLARMEAEKEELSEEIAALQQERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLAAISLEMERQKRDAQSRQE 1106
Cdd:COG4372    248 KEELLEEVILKEIEELELAILVEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKK 327

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|
gi 1958776745 1107 QDRNTVNALTSELRDLRAQLEEATAAHAQQVKELQEQTGN 1146
Cdd:COG4372    328 LELALAILLAELADLLQLLLVGLLDNDVLELLSKGAEAGV 367
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
 854-982 4.62e-03

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 41.99  E-value: 4.62e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  854 QALRESQRQVEALERaarEKEAMAKER-AGLAVQLAAAEREGRTLSEETIRLRLEKEALESSLFDVQRQLAQLEARREQL 932
Cdd:COG0542    411 EELDELERRLEQLEI---EKEALKKEQdEASFERLAELRDELAELEEELEALKARWEAEKELIEEIQELKEELEQRYGKI 487

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1958776745  933 EADSQALLLAKETLTGELAGLRQQVTATEEKAALDKelMT----QKLVQAERET 982
Cdd:COG0542    488 PELEKELAELEEELAELAPLLREEVTEEDIAEVVSR--WTgipvGKLLEGEREK 539
PstA COG4985
ABC-type phosphate transport system, auxiliary component PstA [Inorganic ion transport and ...
 775-854 5.02e-03

ABC-type phosphate transport system, auxiliary component PstA [Inorganic ion transport and metabolism];


Pssm-ID: 444009 [Multi-domain]  Cd Length: 545  Bit Score: 41.83  E-value: 5.02e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  775 QQQAEHATSL-----AVEKQE------RLEQLRLEQevERQGLEGSLCVAEQARealgqqilvLRSERSHLQEQVAQLSR 843
Cdd:COG4985    161 QQRLERALELrdqidDIEKGDigainyQLERLRLKE--RRLELDGQLDDEAQAD---------IEAERAELEAEYAVLEQ 229

                           90
                   ....*....|.
gi 1958776745  844 QLNGRDQELDQ 854
Cdd:COG4985    230 QLDALRQQINR 240
MAD pfam05557
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ...
 587-1020 5.08e-03

Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.


Pssm-ID: 461677 [Multi-domain]  Cd Length: 660  Bit Score: 41.65  E-value: 5.08e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  587 EDAQREAQRLRSANEILSREKGNLSHSLQVAQQQAEDLRQELEKLQAAQEELRRQHTQLEDQQEDTV---QEGARARREL 663
Cdd:pfam05557   41 RQLDRESDRNQELQKRIRLLEKREAEAEEALREQAELNRLKKKYLEALNKKLNEKESQLADAREVISclkNELSELRRQI 120

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  664 ERSHRQLEQLEVKRSGLTKELVEVREALSCAVLQRDVLQTEKAEVAEA------LTKAEAGRAQLELSVTKLRAEEASLR 737
Cdd:pfam05557  121 QRAELELQSTNSELEELQERLDLLKAKASEAEQLRQNLEKQQSSLAEAeqrikeLEFEIQSQEQDSEIVKNSKSELARIP 200

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  738 DSLSKMSALNESLAQDKlELNRLIAQLEEEKAALLGRQQQAEHATSLAVEKQerLEQLRLEQEV-ERQGLEGSLCVAEQA 816
Cdd:pfam05557  201 ELEKELERLREHNKHLN-ENIENKLLLKEEVEDLKRKLEREEKYREEAATLE--LEKEKLEQELqSWVKLAQDTGLNLRS 277

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  817 REALGQQILVLRSERSHLQEQVAQL---SRQLNGRDQELDQALRESQRQVEALERAAREKEAMaKERAGLAVQLAAAERE 893
Cdd:pfam05557  278 PEDLSRRIEQLQQREIVLKEENSSLtssARQLEKARRELEQELAQYLKKIEDLNKKLKRHKAL-VRRLQRRVLLLTKERD 356

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  894 G-----------RTLSEETIRLRLEKEALESSLFDVQRQLAQLEARREQLEADSQALLLAKETLTGELAGLRQQVTATEe 962
Cdd:pfam05557  357 GyrailesydkeLTMSNYSPQLLERIEEAEDMTQKMQAHNEEMEAQLSVAEEELGGYKQQAQTLERELQALRQQESLAD- 435

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1958776745  963 kaaldkelmtqklVQAERETQASLREQRAAHEEDLQRLQREKEAAwrELQAERAQLQG 1020
Cdd:pfam05557  436 -------------PSYSKEEVDSLRRKLETLELERQRLREQKNEL--EMELERRCLQG 478
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
 747-846 5.11e-03

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 41.99  E-value: 5.11e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  747 NESLAQDKLELNRLIAQLEEEKAALLGRQQQA--EHATSLAVE---KQERLEQLRLEQEVERQGLEGSLCVAEQAREALG 821
Cdd:COG0542    406 IDSKPEELDELERRLEQLEIEKEALKKEQDEAsfERLAELRDElaeLEEELEALKARWEAEKELIEEIQELKEELEQRYG 485

                           90       100
                   ....*....|....*....|....*
gi 1958776745  822 qQILVLRSERSHLQEQVAQLSRQLN 846
Cdd:COG0542    486 -KIPELEKELAELEEELAELAPLLR 509
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 677-1027 5.50e-03

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 41.86  E-value: 5.50e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  677 RSGLTKELVEVREALSCAVLQRDVLQTEKAEVAEALTKAEAGRAQLElsvtklrAEEASLRDSLSKMS---ALNESLAQD 753
Cdd:COG3096    280 RRELSERALELRRELFGARRQLAEEQYRLVEMARELEELSARESDLE-------QDYQAASDHLNLVQtalRQQEKIERY 352

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  754 KLELNRLIAQLEEEKAALLGRQQQAEHATSLAVEKQERLEQLRLEQEVERQGLEgslcvaEQAREALGQQILVLRSERSH 833
Cdd:COG3096    353 QEDLEELTERLEEQEEVVEEAAEQLAEAEARLEAAEEEVDSLKSQLADYQQALD------VQQTRAIQYQQAVQALEKAR 426

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  834 --------LQEQVAQLSRQLNGRDQELDQALRESQRQVEALERAAREKEAM--AKERAGLAVQLAAAEREGRTLSEETIR 903
Cdd:COG3096    427 alcglpdlTPENAEDYLAAFRAKEQQATEEVLELEQKLSVADAARRQFEKAyeLVCKIAGEVERSQAWQTARELLRRYRS 506

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  904 LRL---EKEALESSLFDVQRQLAQLEARREQLEADSQAL---LLAKETLTGELAGLRQQVTATEEKAALDKELMTQkLVQ 977
Cdd:COG3096    507 QQAlaqRLQQLRAQLAELEQRLRQQQNAERLLEEFCQRIgqqLDAAEELEELLAELEAQLEELEEQAAEAVEQRSE-LRQ 585

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1958776745  978 AERETQASLREQRA------AHEEDLQRLQREKEAAWRELQAERAQLQGQLQQERE 1027
Cdd:COG3096    586 QLEQLRARIKELAArapawlAAQDALERLREQSGEALADSQEVTAAMQQLLERERE 641
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
 574-708 5.86e-03

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 41.61  E-value: 5.86e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  574 RLRDQTATSVQAQEDAQREAQRLRSANEILSREKGNLShslqvaQQQAEDLRQELEKLQAAQEELRRQHtqleDQQEDTV 653
Cdd:COG0542    401 RVRMEIDSKPEELDELERRLEQLEIEKEALKKEQDEAS------FERLAELRDELAELEEELEALKARW----EAEKELI 470

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1958776745  654 QEGARARRELERSHRQLEQLEVKRSGLTKELVEVREALSCAVLQRDVlqtekAEV 708
Cdd:COG0542    471 EEIQELKEELEQRYGKIPELEKELAELEEELAELAPLLREEVTEEDI-----AEV 520
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 568-930 6.06e-03

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 41.42  E-value: 6.06e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  568 LEEQLQRLRDQTATSVQAQEDAQR----EAQRLRSANEILSREKGNLSHSLQVAQQQAEDLRQELEKLQAAQEELRRQHT 643
Cdd:pfam07888   32 LQNRLEECLQERAELLQAQEAANRqrekEKERYKRDREQWERQRRELESRVAELKEELRQSREKHEELEEKYKELSASSE 111

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  644 QLEDQQEDTVQEGARARRELERSHRQLEQLEVKRSGLTKELVEVREALSCAVLQRDVLQTEKAEVAEALTKAEAGRAQLE 723
Cdd:pfam07888  112 ELSEEKDALLAQRAAHEARIRELEEDIKTLTQRVLERETELERMKERAKKAGAQRKEEEAERKQLQAKLQQTEEELRSLS 191

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  724 LSVTKLRAEEASLRDSLSKMSALNESLAQDKLELNRLIAQLEEEKAALLGRQQQAEHATSLAVEKQERLEQLRLEQEVER 803
Cdd:pfam07888  192 KEFQELRNSLAQRDTQVLQLQDTITTLTQKLTTAHRKEAENEALLEELRSLQERLNASERKVEGLGEELSSMAAQRDRTQ 271

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  804 QGLEGSLCVAEQAREALGQQILVLRSERSHLQEQVAQLSRQLNGRDQELDQALRESQRQVEALERAAREKEA----MAKE 879
Cdd:pfam07888  272 AELHQARLQAAQLTLQLADASLALREGRARWAQERETLQQSAEADKDRIEKLSAELQRLEERLQEERMEREKleveLGRE 351

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1958776745  880 RAGLAVQLAAAEREGRTLSEETIRLRLEKEALESSLFDVQRQLAQLEARRE 930
Cdd:pfam07888  352 KDCNRVQLSESRRELQELKASLRVAQKEKEQLQAEKQELLEYIRQLEQRLE 402
COG5281 COG5281
Phage-related minor tail protein [Mobilome: prophages, transposons];
973-1471 7.28e-03

Phage-related minor tail protein [Mobilome: prophages, transposons];


Pssm-ID: 444092 [Multi-domain]  Cd Length: 603  Bit Score: 41.13  E-value: 7.28e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  973 QKLVQAERETQASLREQRAAHEEDLQRLQREKEAAWRELQAERAQLQGQLQQEREELLARMEAEKEELSEEIAALQQERD 1052
Cdd:COG5281      2 AALAAAAALAAAAAAAAASAAAAAAAAALAAAAAAAAAAAGLAAAAAAAAAASLAAAAAAAALAAAAAAAAAAAAADALA 81

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1053 EGLLLAESEKQQALSLKESEKTALSEKLmgTRHSLAAISLEMERQKRDAQSRQEQDRNTVNALTSELRDLRAQLEEATAA 1132
Cdd:COG5281     82 AALAEDAAAAAAAAEAALAALAAAALAL--AAAALAEAALAAAAAAAAAAAAAAAAAAAAAAAAAEAAKAAAAAAAAAAL 159

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1133 HAQQVKELQEQTGNLGRQREACMREAEELRTQLRLLEDTRDGLRRELLEAQRKVRDSQDSSEAHRQEASELRRSLSEGTK 1212
Cdd:COG5281    160 AAAAAAAAAAAAAAAAAAALAAASAAAAAAAAKAAAEAAAEAAAAAEAAAAAAAAAAEAAAAEAQALAAAALAEQAALAA 239

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1213 EREALRRSNEELRTAVKKAESERISLKLANEdkEQKLALLEEARMSVAKEAGELRASLQEVERSRLEARRELQELRRQMK 1292
Cdd:COG5281    240 ASAAAQALAALAAAAAAAALALAAAAELALT--AQAEAAAAAAAAAAAAAQAAEAAAAAAEAQALAAAAAAAAAQLAAAA 317

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1293 TLDSDNGRLGRELADLQSRLALGERTEKESRREVLGLRQKVLKGESSLEALKQELQGSQRKLQEQEAEFRARERGLLGSL 1372
Cdd:COG5281    318 AAAAQALRAAAQALAALAQRALAAAALAAAAQEAALAAAAAALQAALEAAAAAAAAELAAAGDWAAGAKAALAEYADSAT 397

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1373 EEARGAEKKLLDSARSLELRLEGVRAETSELGLRLSAAEGRAQGLEVELARVEAQRRVAEAQLGGLRSALRRGLGLGRVS 1452
Cdd:COG5281    398 NVAAQVAQAATSAFSGLTDALAGAVTTGKLLFDALASSIASIADALANAALASAADALGGALAGALGGLFGGGGGAAAGA 477

                          490
                   ....*....|....*....
gi 1958776745 1453 SSPAREAPAGGSGDGLSSP 1471
Cdd:COG5281    478 AVYAGALGPFASGGVVSGP 496
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 532-1172 7.70e-03

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 41.49  E-value: 7.70e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  532 KRQLQVQDMRGRYEASQDLLGSVRKQlsdseGERRGLEEQLQRLRDQTATSVQAQEDAQREAQRLRSANEILSREkgnLS 611
Cdd:TIGR00618  257 KKQQLLKQLRARIEELRAQEAVLEET-----QERINRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKL---LM 328

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  612 HSLQVAQQQA--EDLRQELEKLQAAQEELRRQHTQLEDQQEDTVQEGARaRRELERSHRQLEQLEVKRSGLTKELVEVRE 689
Cdd:TIGR00618  329 KRAAHVKQQSsiEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTL-TQHIHTLQQQKTTLTQKLQSLCKELDILQR 407

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  690 A--------LSCAVLQRDVLQTEKAEVAEaLTKAEAGRAQLELSVTKLRAEEASLRDSLSKMSALNESLAQDKLelnrlI 761
Cdd:TIGR00618  408 EqatidtrtSAFRDLQGQLAHAKKQQELQ-QRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQ-----I 481

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  762 AQLEEEKAALLGRQQQAEHATSLAVEKQERLEQLRLEQEVERQGLEGSLCVAEQAREALGQQILVLRSERSHLQEQVAQL 841
Cdd:TIGR00618  482 HLQETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQDIDNPGPLTRRMQRGEQTYAQLETSEEDVYHQLTSERKQRASL 561

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  842 SRQLNGRDQELDQALRESQRQVEALERAAREKEAMAKEraglavqlaaaereGRTLSEETIRLRLEKEALESSLfdvQRQ 921
Cdd:TIGR00618  562 KEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDL--------------TEKLSEAEDMLACEQHALLRKL---QPE 624

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  922 LAQLEARREQLEAdSQALLLAKETLTGELAGLRQQvtATEEKAALDKELMTQKLVQAEREtqaslrEQRAAHEEDLQRLQ 1001
Cdd:TIGR00618  625 QDLQDVRLHLQQC-SQELALKLTALHALQLTLTQE--RVREHALSIRVLPKELLASRQLA------LQKMQSEKEQLTYW 695

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1002 REKEAAWRELQAERAQLQGQLQQEREELLARMEAEKEELSEEIAALQQerdeglLLAESEKQQALSLKESEKTALSEKLM 1081
Cdd:TIGR00618  696 KEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQ------SLKELMHQARTVLKARTEAHFNNNEE 769

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1082 GTrhSLAAISLEMERQKRDAQSRQEQDRNTVNALTSELRDLRAQLEEATAAHAQQVKELQEQTGNLGRQREACMREAEEL 1161
Cdd:TIGR00618  770 VT--AALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQEEEQFLSRLEEKSATLGEI 847

                          650
                   ....*....|.
gi 1958776745 1162 RTQLRLLEDTR 1172
Cdd:TIGR00618  848 THQLLKYEECS 858
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
1115-1235 8.10e-03

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 41.00  E-value: 8.10e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1115 LTSELRDLRAQLEEATAAHAQ-QVKELQEQTGNLGRQREACMREAEELRTQLRLLEDTRDGLRRELLEAQRKVRDSQDSS 1193
Cdd:COG2433    385 LIEKELPEEEPEAEREKEHEErELTEEEEEIRRLEEQVERLEAEVEELEAELEEKDERIERLERELSEARSEERREIRKD 464

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*
gi 1958776745 1194 ---EAHRQEASELRRSLSEGTKEREALRRSNEELRTAVKKAESER 1235
Cdd:COG2433    465 reiSRLDREIERLERELEEERERIEELKRKLERLKELWKLEHSGE 509
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
617-883 8.70e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 40.66  E-value: 8.70e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  617 AQQQAEDLRQELEKLQAAQEELRRQHTQLEDQQEDTVQEGARARRELERSHRQLEQLEVKRSGLTKELVEVREALSCAVL 696
Cdd:COG4372     29 LSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQE 108

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  697 QRDVLQTEKAEVAEALTKAEAGRAQLELSVTKLRAEEASLRDSLSKMSALNESLAQDKLELNRLIAQLEEEKAALLGRQQ 776
Cdd:COG4372    109 EAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAEAEQALDEL 188

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  777 QAEHATSLAVEKQERLEQLRLEQEVERQGLEGSLCVAEQAREALGQQILVLRSERSHLQEQVAQLSRQLNGRDQELDQAL 856
Cdd:COG4372    189 LKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELELAIL 268

                          250       260
                   ....*....|....*....|....*..
gi 1958776745  857 RESQRQVEALERAAREKEAMAKERAGL 883
Cdd:COG4372    269 VEKDTEEEELEIAALELEALEEAALEL 295
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
886-1218 9.16e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 40.66  E-value: 9.16e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  886 QLAAAEREGRTLSEETIRLRLEKEALESSLFDVQRQLAQLEARREQLEADSQALLLAKETLTGELAGLRQQVTATEEK-A 964
Cdd:COG4372     39 ELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQEEAEELQEElE 118

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  965 ALDKELMT-QKLVQAERETQASLREQRAAHEEDLQRLQREKEAAWRELQAERAQLQGQLQQEREELLARMEAEKEELSEE 1043
Cdd:COG4372    119 ELQKERQDlEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAEAEQALDELLKEANRNAEK 198

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1044 IAALQQERDEGLLLAESEKQQALSLKESEKTALSEklmGTRHSLAAISLEMERQKRDAQSRQEQDRNTVNALTSELRDLR 1123
Cdd:COG4372    199 EEELAEAEKLIESLPRELAEELLEAKDSLEAKLGL---ALSALLDALELEEDKEELLEEVILKEIEELELAILVEKDTEE 275

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1124 AQLEEATAAHAQQVKELQEQTGNLGRQREACMREAEELRTQLRLLEDTRDGLRRELLEAQRKVRDSQDSSEAHRQEASEL 1203
Cdd:COG4372    276 EELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLELALAILLAELADLLQLLLVGLLDNDV 355

                          330
                   ....*....|....*
gi 1958776745 1204 RRSLSEGTKEREALR 1218
Cdd:COG4372    356 LELLSKGAEAGVADG 370
PspC_subgroup_1 NF033838
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, ...
 1274-1624 9.44e-03

pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.


Pssm-ID: 468201 [Multi-domain]  Cd Length: 684  Bit Score: 41.15  E-value: 9.44e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1274 ERSRLEARRELQ-ELRRQMKTLDSDNGRLGRELADLQSRLALGERTEK----ESRREVLGLRQKVLK---GESSLEALKQ 1345
Cdd:NF033838   109 EKSEAELTSKTKkELDAAFEQFKKDTLEPGKKVAEATKKVEEAEKKAKdqkeEDRRNYPTNTYKTLEleiAESDVEVKKA 188

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1346 ELQGSQRKLQEQEAEfrarergllgslEEARGAEKKLlDSARSLELRLEGVRAETSElglrlsaAEGRAQGLEVELARVE 1425
Cdd:NF033838   189 ELELVKEEAKEPRDE------------EKIKQAKAKV-ESKKAEATRLEKIKTDREK-------AEEEAKRRADAKLKEA 248

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1426 AQRRVAEAQLGGLRSALRRGlglgrVSSSPAReapaggsgdglssPSPLEYSPRSQPPSPGPVASPApPDLDPEA-VRDA 1504
Cdd:NF033838   249 VEKNVATSEQDKPKRRAKRG-----VLGEPAT-------------PDKKENDAKSSDSSVGEETLPS-PSLKPEKkVAEA 309

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745 1505 LRDFLQELRSAQRERDELRvqtstlsqqlaemeaeRDHAASRAKQLQKAVAESEEAWRSADRRLSGAQAELALQEESVRR 1584
Cdd:NF033838   310 EKKVEEAKKKAKDQKEEDR----------------RNYPTNTYKTLELEIAESDVKVKEAELELVKEEAKEPRNEEKIKQ 373

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*
gi 1958776745 1585 SRRECRATLDQMAVLE-----RSLQATESELRASQEKVNKMKATE 1624
Cdd:NF033838   374 AKAKVESKKAEATRLEkiktdRKKAEEEAKRKAAEEDKVKEKPAE 418
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 80-286 9.61e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 40.52  E-value: 9.61e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745   80 SLQEENQLLQQELSRVEDLLAQSRAERDELAIKYNAINERLEQAVRlETGELEAQ------EPRGLVRQSVELRRQLQEE 153
Cdd:COG4942     24 EAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALAR-RIRALEQElaaleaELAELEKEIAELRAELEAQ 102

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776745  154 QASYRRKLQA-YQEGQQRQAQLV---------QRLQAKILQYKKQCSEMEKQLLERSTELEQQRLRDTEHSQDLDRALLR 223
Cdd:COG4942    103 KEELAELLRAlYRLGRQPPLALLlspedfldaVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAE 182

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1958776745  224 LEEEQQRSASLAQVNDMLREQLDQANLANQTLSEDICKVTSDWTRSCKELEQREATWRREEES 286
Cdd:COG4942    183 LEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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