|
Name |
Accession |
Description |
Interval |
E-value |
| Mitofilin |
pfam09731 |
Mitochondrial inner membrane protein; Mitofilin controls mitochondrial cristae morphology. ... |
43-667 |
0e+00 |
|
Mitochondrial inner membrane protein; Mitofilin controls mitochondrial cristae morphology. Mitofilin is enriched in the narrow space between the inner boundary and the outer membranes, where it forms a homotypic interaction and assembles into a large multimeric protein complex. The first 78 amino acids contain a typical amino-terminal-cleavable mitochondrial presequence rich in positive-charged and hydroxylated residues and a membrane anchor domain. In addition, it has three centrally located coiled coil domains.
Pssm-ID: 430783 [Multi-domain] Cd Length: 618 Bit Score: 572.09 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958769484 43 AGKIAGAGLLFVGGGIGGTILYAKWDSHFRESVEKTIPYSDKLFGMVLGSAPYTVPlpkKPIQSGPLKISSVSEVMTDSE 122
Cdd:pfam09731 4 FGKFFVALVLIVGVGYGGVVLYAYKDDNFRDFFEEYIPYGEEVVLYALGEDPPLAP---KPKTFRPLQPSVVSAVTGESK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958769484 123 LPMAQ--------------------------TQETNGDTP-----ASAALAKSLEDALNQTATVTRQTITAQNAAVQAVK 171
Cdd:pfam09731 81 EPKEEkkqvkiprqsgvssevaeeekeatkdAAEAKAQLPkseqeKEKALEEVLKEAISKAESATAVAKEAKDDAIQAVK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958769484 172 AHSSTLKTAMDNSEIAGEKKSAQWRTVEGALKErrkavdeaadallkakeeleKMKTIIEDAKKREIAGATPYITAAEEK 251
Cdd:pfam09731 161 AHTDSLKEASDTAEISREKATDSALQKAEALAE--------------------KLKEVINLAKQSEEEAAPPLLDAAPET 220
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958769484 252 LHSMIVDLDSVVKKVQAAQSEAKVVSQYHELVVQARDDFRKELDSITPDITPGWKGMSIsdlagtLSTDDLNALIAHAHR 331
Cdd:pfam09731 221 PPKLPEHLDNVEEKVEKAQSLAKLVDQYKELVASERIVFQQELVSIFPDIIPVLKEDNL------LSNDDLNSLIAHAHR 294
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958769484 332 RIDQLNRELAQQKATEKQHIELALERQKlEEKRAFDSAVAKALEHHRS----EIQAEQDRKVEEVRDAMENEMRTQLRRQ 407
Cdd:pfam09731 295 EIDQLSKKLAELKKREEKHIERALEKQK-EELDKLAEELSARLEEVRAadeaQLRLEFEREREEIRESYEEKLRTELERQ 373
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958769484 408 AAAHTDHLRDVLKVQEQELKFEFEQDLSEKLSEQElefhrrsqeqmDNFTLDINTAYARLRGIEQAVQSHAVAEEEARKA 487
Cdd:pfam09731 374 AEAHEEHLKDVLVEQEIELQREFLQDIKEKVEEER-----------AGRLLKLNELLANLKGLEKATSSHSEVEDENRKA 442
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958769484 488 HQLWLSVEALKYSMKTSSAEMPTIPLGSAVEAIRVSCSDNEFTQALTAAIPPESLTRGVYSEETLRARFYAVQKLAGRVA 567
Cdd:pfam09731 443 QQLWLAVEALRSTLEDGSADSRPRPLVRELKALKELASDDEVVKAALASLPEEAYQRGVYTEAALRERFRRVAKEVRKVS 522
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958769484 568 MIDETKNSLYQYFLSYLQSLLLFPPKQlkppAELYPEDINTFKLLSYASYCIEHGDLELAAKFVNQLKGESRRVAQDWLK 647
Cdd:pfam09731 523 LIDPEGAGLLSHALSYLLSKLMFKPKQ----GEADPAGDDVESILARAEYYLEEGDLDSAAREMNSLKGWSKKLASDWLK 598
|
650 660
....*....|....*....|
gi 1958769484 648 EARMTLETKQIVEILTTYAS 667
Cdd:pfam09731 599 EARRRLEVQQALELLQAEAA 618
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
111-498 |
1.75e-10 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 64.78 E-value: 1.75e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958769484 111 ISSVSEVMTDSELPMAQTQETNGDTPASAALAKSLEDALNQTATVTRQTITAQNAAVQAVKAHSSTLKTAMDNSEIAGEK 190
Cdd:PTZ00121 1229 VKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAK 1308
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958769484 191 KSAQWRTVEGALKERRKAVDEAADALLKAKEELEKMktiiEDAKKREIAGATPYITAAEEKLHSMIVDLDSVVKKVQAAQ 270
Cdd:PTZ00121 1309 KKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKA----AEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAK 1384
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958769484 271 SEAKVVSQYHELVVQARDDfRKELDSITPDITPGWKGMSISDLAGTLSTDDLNALIAHAHRRIDQLNR--------ELAQ 342
Cdd:PTZ00121 1385 KKAEEKKKADEAKKKAEED-KKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKkaeeakkaEEAK 1463
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958769484 343 QKATEKQHIELAleRQKLEEKRAFDSAVAKALEHHR----SEIQAEQDRKVEEVRDAMENEMRTQLRR-QAAAHTDHLRD 417
Cdd:PTZ00121 1464 KKAEEAKKADEA--KKKAEEAKKADEAKKKAEEAKKkadeAKKAAEAKKKADEAKKAEEAKKADEAKKaEEAKKADEAKK 1541
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958769484 418 VLKVQEQElkfefEQDLSEKLSEQElefHRRSQEQMDNFTLDINTAYAR---LRGIEQA---------VQSHAVAEEEAR 485
Cdd:PTZ00121 1542 AEEKKKAD-----ELKKAEELKKAE---EKKKAEEAKKAEEDKNMALRKaeeAKKAEEArieevmklyEEEKKMKAEEAK 1613
|
410
....*....|...
gi 1958769484 486 KAHQLWLSVEALK 498
Cdd:PTZ00121 1614 KAEEAKIKAEELK 1626
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
166-490 |
1.94e-08 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 58.02 E-value: 1.94e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958769484 166 AVQAVKAHssTLKTAMDnsEIAGEKKSAQWRTVEGALKERRKAVDEAADALLKAKEELEKMKTIIEDAKKReiagatpyI 245
Cdd:COG1196 209 AEKAERYR--ELKEELK--ELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLE--------L 276
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958769484 246 TAAEEKLHSMIVDLDSVVKKVQAAQSEAKVVSQYHELVVQARDDFRKELDSITpditpgwkgMSISDLAGTLstDDLNAL 325
Cdd:COG1196 277 EELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELE---------EELEELEEEL--EELEEE 345
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958769484 326 IAHAHRRIDQLNRELAQQKAT--EKQHIELALERQKLEEKRAFDSAVAKALEHHRSEIQAEQDRKVEEVRDAMENEMRTQ 403
Cdd:COG1196 346 LEEAEEELEEAEAELAEAEEAllEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEE 425
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958769484 404 LRRQAAAHTDHLRDVLKVQEQELKFEFEQDLSEKLSEQELEFHRRS----QEQMDNFTLDINTAYARLRGIEQAVQSHAV 479
Cdd:COG1196 426 LEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEaallEAALAELLEELAEAAARLLLLLEAEADYEG 505
|
330
....*....|.
gi 1958769484 480 AEEEARKAHQL 490
Cdd:COG1196 506 FLEGVKAALLL 516
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
169-476 |
1.25e-06 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 51.98 E-value: 1.25e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958769484 169 AVKAHSSTLKTamdNSEIagEKKSAQWRTVEGALKERRKAVDEAADALLKAKEELEKMKTIIEDaKKREIAGATPYITAA 248
Cdd:TIGR02168 665 SAKTNSSILER---RREI--EELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEE-LSRQISALRKDLARL 738
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958769484 249 EEKLHSMIVDLDSVVKKVQAAQSEAKVVSQYHELVVQARDDFRKELDSITPDITPGWKGMSISDLAGTLSTDDLNALIAH 328
Cdd:TIGR02168 739 EAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEE 818
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958769484 329 AHRRIDQLNRELAQQKATEKQHIELALERQKLEEKRAFDSAV-----------AKALEHHrSEIQAEQDRKVEEVRDAME 397
Cdd:TIGR02168 819 AANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEieeleelieelESELEAL-LNERASLEEALALLRSELE 897
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958769484 398 NEM---------RTQLRRQAAAHTDHLRDvLKVQEQELKFEFEQdLSEKLSEQ---ELEFHrrsQEQMDNFTLDINTAYA 465
Cdd:TIGR02168 898 ELSeelreleskRSELRRELEELREKLAQ-LELRLEGLEVRIDN-LQERLSEEyslTLEEA---EALENKIEDDEEEARR 972
|
330
....*....|.
gi 1958769484 466 RLRGIEQAVQS 476
Cdd:TIGR02168 973 RLKRLENKIKE 983
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
156-451 |
1.51e-06 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 51.84 E-value: 1.51e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958769484 156 TRQTITAQNAAVQAVKAHSSTLKTAmdnseiagekkSAQWRTVEGALKERRKAVDEAADALLKAKEELEKMKTIIEDAKK 235
Cdd:COG4913 666 AEREIAELEAELERLDASSDDLAAL-----------EEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQD 734
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958769484 236 R----EIAGATPYITAAEEKLHSmiVDLDSVVKKVQA------AQSEAKVVSQYHELV--------------------VQ 285
Cdd:COG4913 735 RleaaEDLARLELRALLEERFAA--ALGDAVERELREnleeriDALRARLNRAEEELEramrafnrewpaetadldadLE 812
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958769484 286 ARDDFRKELDSITPDITPG-----------WKGMSISDLAGTLSTDdlnalIAHAHRRIDQLNRELAQQKATEKQHIELA 354
Cdd:COG4913 813 SLPEYLALLDRLEEDGLPEyeerfkellneNSIEFVADLLSKLRRA-----IREIKERIDPLNDSLKRIPFGPGRYLRLE 887
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958769484 355 LERQKLEEKRAFDSAVAKALEHHRSEIQAEQDRKVEEVRDAMEnemrtQLRRQAAAHTDH-LRDVLKVQEQelkFEFEQD 433
Cdd:COG4913 888 ARPRPDPEVREFRQELRAVTSGASLFDEELSEARFAALKRLIE-----RLRSEEEESDRRwRARVLDVRNH---LEFDAE 959
|
330
....*....|....*...
gi 1958769484 434 LSEKLSEQELEFHRRSQE 451
Cdd:COG4913 960 EIDREDGEEVETYSSSGG 977
|
|
| ARGLU |
pfam15346 |
Arginine and glutamate-rich 1; ARGLU, arginine and glutamate-rich 1 protein family, is ... |
355-489 |
7.62e-06 |
|
Arginine and glutamate-rich 1; ARGLU, arginine and glutamate-rich 1 protein family, is required for the oestrogen-dependent expression of ESR1 target genes. It functions in cooperation with MED1. The family of proteins is found in eukaryotes.
Pssm-ID: 405931 [Multi-domain] Cd Length: 151 Bit Score: 46.20 E-value: 7.62e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958769484 355 LERQKLEE------KRAFDSAVAKALEHHRSEIQAEQDRKVEEVRDAMENEMRTQLRRQAAAhtdhlrdvlKVQEQELKF 428
Cdd:pfam15346 3 AESKLLEEetarrvEEAVAKRVEEELEKRKDEIEAEVERRVEEARKIMEKQVLEELEREREA---------ELEEERRKE 73
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1958769484 429 EFEQDLSEKLSEQELEFHRRSQEQMDNFTLDINTAYARLRGIEQAVQSHAVAEEEARKAHQ 489
Cdd:pfam15346 74 EEERKKREELERILEENNRKIEEAQRKEAEERLAMLEEQRRMKEERQRREKEEEEREKREQ 134
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
203-498 |
9.22e-06 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 49.16 E-value: 9.22e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958769484 203 KERRKAVDEAA----------DALLK---AKEELEKMKTII--------------EDAKK-----------------REI 238
Cdd:COG1196 155 EERRAIIEEAAgiskykerkeEAERKleaTEENLERLEDILgelerqleplerqaEKAERyrelkeelkeleaelllLKL 234
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958769484 239 AGATPYITAAEEKLHSMIVDLDSVVKKVQAAQSEAKVVSQYHELVVQARDDFRKELDSITpditpgwkgMSISDLAGTLs 318
Cdd:COG1196 235 RELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELL---------AELARLEQDI- 304
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958769484 319 tDDLNALIAHAHRRIDQLNRELAQQKATEKQH--------IELALERQKLEEKRAFDSAVAKALEHHRSEIQAEQDRKVE 390
Cdd:COG1196 305 -ARLEERRRELEERLEELEEELAELEEELEELeeeleeleEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEE 383
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958769484 391 EVRDAME------------NEMRTQLRRQAAAHTDHLRDVLKVQEQELKFEFEQDLSEKLSEQELEFHRRSQEQMDNFTL 458
Cdd:COG1196 384 LAEELLEalraaaelaaqlEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLE 463
|
330 340 350 360
....*....|....*....|....*....|....*....|
gi 1958769484 459 DINTAYARLRGIEQAVQshAVAEEEARKAHQLWLSVEALK 498
Cdd:COG1196 464 LLAELLEEAALLEAALA--ELLEELAEAAARLLLLLEAEA 501
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
127-441 |
1.14e-05 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 49.07 E-value: 1.14e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958769484 127 QTQETNGDTPASAALAKSLEDALNQTATVTRQTITAQNAAVQAVKAHSSTLKTAMdnseiagekkSAQWRTVEGALKERR 206
Cdd:pfam12128 662 KQSEKDKKNKALAERKDSANERLNSLEAQLKQLDKKHQAWLEEQKEQKREARTEK----------QAYWQVVEGALDAQL 731
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958769484 207 KAVDEAADAL-LKAKEELEKMKTiiedAKKREIAGATPyitaAEEKLHSMIVDLDSVVKKV-QAAQSEAKVVSQ---YHE 281
Cdd:pfam12128 732 ALLKAAIAARrSGAKAELKALET----WYKRDLASLGV----DPDVIAKLKREIRTLERKIeRIAVRRQEVLRYfdwYQE 803
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958769484 282 LVVQARDDFRKELDSITpditpgwkgMSISDLagtlsTDDLNALIAHAHRRIDQLNRELaqqKATEKQHIELALERQKLe 361
Cdd:pfam12128 804 TWLQRRPRLATQLSNIE---------RAISEL-----QQQLARLIADTKLRRAKLEMER---KASEKQQVRLSENLRGL- 865
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958769484 362 ekRAFDSAVAKALEHHRSE----IQAEQDRKVEEVRDAMENEMrtqlrRQAAAHTDHLRDVLKVQEQELKFEFEQDLSEK 437
Cdd:pfam12128 866 --RCEMSKLATLKEDANSEqaqgSIGERLAQLEDLKLKRDYLS-----ESVKKYVEHFKNVIADHSGSGLAETWESLREE 938
|
....
gi 1958769484 438 LSEQ 441
Cdd:pfam12128 939 DHYQ 942
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
201-466 |
4.67e-05 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 46.83 E-value: 4.67e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958769484 201 ALKERRKAVDEAADALLKAKEELEKMKTIIEDAKKREIAgatpyitaaeeklHSMIVDLDSVVKKVQAAQSEakvvsqyh 280
Cdd:COG4913 611 KLAALEAELAELEEELAEAEERLEALEAELDALQERREA-------------LQRLAEYSWDEIDVASAERE-------- 669
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958769484 281 elvVQARDDFRKELDSitpditpgwkgmSISDLAGtlstddLNALIAHAHRRIDQLNRELA----QQKATEKQHIELALE 356
Cdd:COG4913 670 ---IAELEAELERLDA------------SSDDLAA------LEEQLEELEAELEELEEELDelkgEIGRLEKELEQAEEE 728
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958769484 357 RQKLEEkrAFDSAVAKALEHHRSEI-----QAEQDRKVEEVRDAMENEmRTQLRRQAAAHTDHLRDVLkvqeQELKFEFE 431
Cdd:COG4913 729 LDELQD--RLEAAEDLARLELRALLeerfaAALGDAVERELRENLEER-IDALRARLNRAEEELERAM----RAFNREWP 801
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 1958769484 432 QDLSE----------------KLSEQEL-----EFHRRSQEQMDNFTLDINTAYAR 466
Cdd:COG4913 802 AETADldadleslpeylalldRLEEDGLpeyeeRFKELLNENSIEFVADLLSKLRR 857
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
126-490 |
6.27e-05 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 46.67 E-value: 6.27e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958769484 126 AQTQETNGDTPASAALAKSLEDALnQTATVTRQTITAQNAAVQAVKAHSSTLKTAMDNSEIAGEKKSAQWRTVEGALKER 205
Cdd:PTZ00121 1348 AKAEAEAAADEAEAAEEKAEAAEK-KKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKK 1426
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958769484 206 RKAVDEAADALLKAKE--ELEKMKTIIEDAKKREIAGATpyitaAEEKlhsmivdldsvvKKVQAAQSEAKVVSQYHELV 283
Cdd:PTZ00121 1427 AEEKKKADEAKKKAEEakKADEAKKKAEEAKKAEEAKKK-----AEEA------------KKADEAKKKAEEAKKADEAK 1489
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958769484 284 VQArDDFRKELDSITPDITPGWKGMSISDLAGTLSTDDLNAliAHAHRRIDQLNRELAQQKATEKQHIElalERQKLEEK 363
Cdd:PTZ00121 1490 KKA-EEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKK--AEEAKKADEAKKAEEKKKADELKKAE---ELKKAEEK 1563
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958769484 364 RAFDSAVAKALEHHRSEIQAEQDRKVEEVRDAMENEMRTQLRRQAAAHTDHLRDVLKVQEQELKFEFEQDLSEKLSEQEL 443
Cdd:PTZ00121 1564 KKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEA 1643
|
330 340 350 360
....*....|....*....|....*....|....*....|....*..
gi 1958769484 444 EFHRRSQEqmdnftLDINTAYARLRGIEQAVQshavAEEEARKAHQL 490
Cdd:PTZ00121 1644 EEKKKAEE------LKKAEEENKIKAAEEAKK----AEEDKKKAEEA 1680
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
329-490 |
2.42e-04 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 44.75 E-value: 2.42e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958769484 329 AHRRIDQLNRELAQQKATEKQHIElalERQKLEEKRAFDSAvAKALEHHRSEI--------QAEQDRKVEEVRDAMENEM 400
Cdd:PTZ00121 1120 AKKKAEDARKAEEARKAEDARKAE---EARKAEDAKRVEIA-RKAEDARKAEEarkaedakKAEAARKAEEVRKAEELRK 1195
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958769484 401 RTQLRR-QAAAHTDHLRDVLKVQEQELKFEFEQDLSEKLSEQELEFHRRSQEQMDNFTLdinTAYARLRGIEQAVQSHAV 479
Cdd:PTZ00121 1196 AEDARKaEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEI---RKFEEARMAHFARRQAAI 1272
|
170
....*....|.
gi 1958769484 480 AEEEARKAHQL 490
Cdd:PTZ00121 1273 KAEEARKADEL 1283
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
212-449 |
2.46e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 43.98 E-value: 2.46e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958769484 212 AADALLKAKEELEKMKTIIEdAKKREIAGATPYITAAEEKLHSMIVDLDSVVKKVQAAQSEAKVVSQYHELVVQARDDFR 291
Cdd:COG4942 18 QADAAAEAEAELEQLQQEIA-ELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELR 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958769484 292 KELDSITPDITP----GWKGMSISDLAGTLSTDDLNALIAHAhRRIDQLNRELAQQ-KATEKQHIELALERQKLEEKRAF 366
Cdd:COG4942 97 AELEAQKEELAEllraLYRLGRQPPLALLLSPEDFLDAVRRL-QYLKYLAPARREQaEELRADLAELAALRAELEAERAE 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958769484 367 DSAVAKALEHHRSEIQAEQDRKveevrdameNEMRTQLRRQAAAHTDHLRDvLKVQEQELkfefeQDLSEKLSEQELEFH 446
Cdd:COG4942 176 LEALLAELEEERAALEALKAER---------QKLLARLEKELAELAAELAE-LQQEAEEL-----EALIARLEAEAAAAA 240
|
...
gi 1958769484 447 RRS 449
Cdd:COG4942 241 ERT 243
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
233-489 |
4.46e-04 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 43.89 E-value: 4.46e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958769484 233 AKKREIAGATPYITAAEEKLHsmivdldsvvkkvqAAQSEAKVVSQYHELVVQARDDFRKELDSITPDItpgwkgmsisd 312
Cdd:TIGR02168 674 ERRREIEELEEKIEELEEKIA--------------ELEKALAELRKELEELEEELEQLRKELEELSRQI----------- 728
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958769484 313 lagtlstDDLNALIAHAHRRIDQLNRELAQQKATEKqhiELALERQKLEEKRAFDSAVAKALEHHRseiqAEQDRKVEEV 392
Cdd:TIGR02168 729 -------SALRKDLARLEAEVEQLEERIAQLSKELT---ELEAEIEELEERLEEAEEELAEAEAEI----EELEAQIEQL 794
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958769484 393 RDAMENEmRTQLRRQAAAHTDHLRDVLKVQEQELKFEFEQDLSEKLSEQELEFHRRSQEQMDNFTLDINTAYARLRGIEQ 472
Cdd:TIGR02168 795 KEELKAL-REALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELES 873
|
250 260
....*....|....*....|
gi 1958769484 473 AVQSHAV---AEEEARKAHQ 489
Cdd:TIGR02168 874 ELEALLNeraSLEEALALLR 893
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
162-507 |
5.99e-04 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 43.59 E-value: 5.99e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958769484 162 AQNAAVQAVKAHSSTLKTAMDNSEIAGEKKSAQWRTVEGALKERRKAVDEAADALLKAKEELEKMKTI---IEDAKKREI 238
Cdd:PTZ00121 1089 ADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIarkAEDARKAEE 1168
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958769484 239 AGATPYITAAEEKLHSMIVDLDSVVKKVQAAQsEAKVVSQYHElvVQARDDFRKELDSitpditpgwkgmsisdlagtls 318
Cdd:PTZ00121 1169 ARKAEDAKKAEAARKAEEVRKAEELRKAEDAR-KAEAARKAEE--ERKAEEARKAEDA---------------------- 1223
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958769484 319 tddlnaliahahRRIDQLNR-ELAQQKATEKQHIElalERQKLEEKRAFDSAVAKALEHHRSEIQAEQDRKVEEVRDAME 397
Cdd:PTZ00121 1224 ------------KKAEAVKKaEEAKKDAEEAKKAE---EERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEE 1288
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958769484 398 NEMRTQLRRQaaahtdhlRDVLKVQEQELKFEfEQDLSEKLSEQELEFHRRSQEQMDNFTLDINTAYARlRGIEQAVQSH 477
Cdd:PTZ00121 1289 KKKADEAKKA--------EEKKKADEAKKKAE-EAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAA-KAEAEAAADE 1358
|
330 340 350
....*....|....*....|....*....|
gi 1958769484 478 AVAEEEARKAHQLWLSVEALKYSMKTSSAE 507
Cdd:PTZ00121 1359 AEAAEEKAEAAEKKKEEAKKKADAAKKKAE 1388
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
248-470 |
1.56e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 41.82 E-value: 1.56e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958769484 248 AEEKLHSMIVDLDSVVKKVQAAQSEAKVVSQYHELVVQARDDFRKELDSITPDItpgwkgmsisDLAGtlstddlnalia 327
Cdd:COG4913 608 NRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEI----------DVAS------------ 665
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958769484 328 hAHRRIDQLNRELAQQKATEKQHIELALERQKLEEKRafdsavaKALEHHRSEIQAEQDRKVEEvrdamenemRTQLRRQ 407
Cdd:COG4913 666 -AEREIAELEAELERLDASSDDLAALEEQLEELEAEL-------EELEEELDELKGEIGRLEKE---------LEQAEEE 728
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1958769484 408 AAAHTDHLRDVLKVQEQELKFEFEQDLSE-KLSEQELEFHRRSQEQMDNFTLDINTAYARLRGI 470
Cdd:COG4913 729 LDELQDRLEAAEDLARLELRALLEERFAAaLGDAVERELRENLEERIDALRARLNRAEEELERA 792
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
334-489 |
1.76e-03 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 41.88 E-value: 1.76e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958769484 334 DQLNRELAQQKATEKQHIELALERQKLEEKRAFDSAVAKALEHHRSEIQAEQDRKVEEVRDAMENEMRTQLRRQAAAH-- 411
Cdd:TIGR00618 256 LKKQQLLKQLRARIEELRAQEAVLEETQERINRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHvk 335
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958769484 412 -------TDHLRDVLKVQEQELKFEFEQDLS---EKLSEQELEFHRRSQEQMDNFTLDINTAYARLRGIEQAVQSHAVAE 481
Cdd:TIGR00618 336 qqssieeQRRLLQTLHSQEIHIRDAHEVATSireISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQREQATIDTR 415
|
....*...
gi 1958769484 482 EEARKAHQ 489
Cdd:TIGR00618 416 TSAFRDLQ 423
|
|
| PRK05035 |
PRK05035 |
electron transport complex protein RnfC; Provisional |
126-274 |
2.13e-03 |
|
electron transport complex protein RnfC; Provisional
Pssm-ID: 235334 [Multi-domain] Cd Length: 695 Bit Score: 41.47 E-value: 2.13e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958769484 126 AQTQETNGDTPASAALAKSLEDALNQTATVTRQTITAQN------AAVQAVKAHSSTLKTAMDNSEIAGEKKSAQwrtve 199
Cdd:PRK05035 535 AEKQAAAAADPKKAAVAAAIARAKAKKAAQQAANAEAEEevdpkkAAVAAAIARAKAKKAAQQAASAEPEEQVAE----- 609
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958769484 200 galKERRKAVDEAADALLKAKEELEKMKTI---IEDAKKREIAGATPYITA----AEEKLHSMIVDLDSVVKKVQAAQSE 272
Cdd:PRK05035 610 ---VDPKKAAVAAAIARAKAKKAEQQANAEpeePVDPRKAAVAAAIARAKArkaaQQQANAEPEEAEDPKKAAVAAAIAR 686
|
..
gi 1958769484 273 AK 274
Cdd:PRK05035 687 AK 688
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
320-488 |
2.30e-03 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 41.59 E-value: 2.30e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958769484 320 DDLNALIAHAHRRIDQLNRELAQQKAtekqhiELALERQKLEEKRAFDSAVAKALEHHRSEIQ------AEQDRKVEEVR 393
Cdd:TIGR02169 705 DELSQELSDASRKIGEIEKEIEQLEQ------EEEKLKERLEELEEDLSSLEQEIENVKSELKeleariEELEEDLHKLE 778
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958769484 394 DAMEN-----------EMRTQLRRQAAAHTDhLRDVLKVQEQEL-KFEFEQDLSEKLSEQELEFHRRSQEQMDNFTLDIN 461
Cdd:TIGR02169 779 EALNDlearlshsripEIQAELSKLEEEVSR-IEARLREIEQKLnRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIE 857
|
170 180
....*....|....*....|....*..
gi 1958769484 462 TAYARLRGIEQAVQSHAVAEEEARKAH 488
Cdd:TIGR02169 858 NLNGKKEELEEELEELEAALRDLESRL 884
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
320-491 |
2.38e-03 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 41.29 E-value: 2.38e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958769484 320 DDLNALIAHAHRRIDQLNRELAQQKATEKQHIELALERQKLEEKRAFDSAVAKALEHHRSEIQAEQDRKVEEVR-DAMEN 398
Cdd:COG4717 74 KELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAELAELPERlEELEE 153
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958769484 399 EMRTqlRRQAAAHTDHLRDVLKVQEQELKFEFEQDLSEKLSEQE--LEFHRRSQEQMDNFTLDINTAYARLRGIEQAVQS 476
Cdd:COG4717 154 RLEE--LRELEEELEELEAELAELQEELEELLEQLSLATEEELQdlAEELEELQQRLAELEEELEEAQEELEELEEELEQ 231
|
170
....*....|....*
gi 1958769484 477 HAVAEEEARKAHQLW 491
Cdd:COG4717 232 LENELEAAALEERLK 246
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
137-444 |
2.41e-03 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 41.46 E-value: 2.41e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958769484 137 ASAALAKSLEDALNQTATVTRQTITAQNAAVQAVKAHSSTLKTAMDNSEIAG----EKKSAQWRTVEGAL-------KER 205
Cdd:COG1196 457 EEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEgvkaALLLAGLRGLAGAVavligveAAY 536
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958769484 206 RKAVDEAADALLKAK--EELEKMKTIIEDAKKREIAGAT--PYITAAEEKLHSMIVDLDSVVKKVQAAQSEAkvvsQYHE 281
Cdd:COG1196 537 EAALEAALAAALQNIvvEDDEVAAAAIEYLKAAKAGRATflPLDKIRARAALAAALARGAIGAAVDLVASDL----READ 612
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958769484 282 LVVQARDDFRKELDSITPDITPGWKGMSISDLAGTLSTDDLNALIAHAHRRIDQLNRELAQQKATEKQhielaLERQKLE 361
Cdd:COG1196 613 ARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAE-----LEELAER 687
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958769484 362 EKRAFDSAVAKALEHHRSEIQAEQDRKVEEVRDAMENEMRTQLRRQAAAHTDHLRDVLKVQEQELKFEFEQDLSEKLSEQ 441
Cdd:COG1196 688 LAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELER 767
|
...
gi 1958769484 442 ELE 444
Cdd:COG1196 768 ELE 770
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
338-511 |
2.71e-03 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 41.26 E-value: 2.71e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958769484 338 RELAQQKATEKQHIELA-LERQKLEEKRAFDSAVAKALEHHRSEIQAEQDRKVEEVRDAMENEMRTqlRRQAAAHTDHLR 416
Cdd:pfam17380 438 RRLEEERAREMERVRLEeQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEE--RKQAMIEEERKR 515
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958769484 417 DVLK---------VQEQELKFEFEQdlsEKLSEQELEFHRRSQEQMDNFTLDINTAYARLRgiEQAVQSHAVAEEEARKA 487
Cdd:pfam17380 516 KLLEkemeerqkaIYEEERRREAEE---ERRKQQEMEERRRIQEQMRKATEERSRLEAMER--EREMMRQIVESEKARAE 590
|
170 180
....*....|....*....|....*.
gi 1958769484 488 HQLWLSVEALK--YSMKTSSAEMPTI 511
Cdd:pfam17380 591 YEATTPITTIKpiYRPRISEYQPPDV 616
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
320-489 |
3.50e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 40.67 E-value: 3.50e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958769484 320 DDLNAL---IAHAHRRIDQL-----NRELAQQKATEKQHIELALERQKLEEKRAFDSAVAKALEHHRSEIQAEQDRK--- 388
Cdd:COG4913 235 DDLERAheaLEDAREQIELLepireLAERYAAARERLAELEYLRAALRLWFAQRRLELLEAELEELRAELARLEAELerl 314
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958769484 389 ------VEEVRDAMENEMR-------TQLRRQAAAHTDHLRDVLKVQEQelkfeFEQ-----DLSEKLSEQEL-EFHRRS 449
Cdd:COG4913 315 earldaLREELDELEAQIRgnggdrlEQLEREIERLERELEERERRRAR-----LEAllaalGLPLPASAEEFaALRAEA 389
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 1958769484 450 QEQMDNFTldintayARLRGIEQAVQSHAVAEEEARKAHQ 489
Cdd:COG4913 390 AALLEALE-------EELEALEEALAEAEAALRDLRRELR 422
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
138-426 |
5.37e-03 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 40.02 E-value: 5.37e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958769484 138 SAALAKS-LEDALNQTATVTRQTITAQNAAVQAVKAHSSTLKTAMdNSEIAGEKKSAqwRTVEGALKERRKAVDEAADAL 216
Cdd:PRK02224 296 DDLLAEAgLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAH-NEEAESLREDA--DDLEERAEELREEAAELESEL 372
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958769484 217 LKAKEELEKMKTIIEDAKKReiagatpyITAAEEKLHSMIVDLDSVvkkvqaaqseakvvSQYHELVVQARDDFRKELDS 296
Cdd:PRK02224 373 EEAREAVEDRREEIEELEEE--------IEELRERFGDAPVDLGNA--------------EDFLEELREERDELREREAE 430
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958769484 297 ITPDITPGWK-----------------GMSISDLAGTLSTDDlnaliahAHRRIDQLNRELAQQKATE----------KQ 349
Cdd:PRK02224 431 LEATLRTARErveeaealleagkcpecGQPVEGSPHVETIEE-------DRERVEELEAELEDLEEEVeeveerleraED 503
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958769484 350 HIELALERQKLEEKRafdSAVAKALEHHRSEIQAEQDRkVEEVR---DAMENEMRTQLRRQAAAH--TDHLRDVLKVQEQ 424
Cdd:PRK02224 504 LVEAEDRIERLEERR---EDLEELIAERRETIEEKRER-AEELReraAELEAEAEEKREAAAEAEeeAEEAREEVAELNS 579
|
..
gi 1958769484 425 EL 426
Cdd:PRK02224 580 KL 581
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
206-427 |
6.35e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 39.90 E-value: 6.35e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958769484 206 RKAVDEAADALLKAKEELEKMKTIIEDAK-KREIAGATPYITAAEEKLHSMIVDLDSVVKKVQAAQSEAKVvsqyhELVV 284
Cdd:COG4913 220 EPDTFEAADALVEHFDDLERAHEALEDAReQIELLEPIRELAERYAAARERLAELEYLRAALRLWFAQRRL-----ELLE 294
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958769484 285 QARDDFRKELDSITPDItpgwkgmsisdlagtlstDDLNALIAHAHRRIDQLNRELAQQKATEKQHIE-----LALERQK 359
Cdd:COG4913 295 AELEELRAELARLEAEL------------------ERLEARLDALREELDELEAQIRGNGGDRLEQLEreierLERELEE 356
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1958769484 360 LEEKRA-FDSAV----------AKALEHHRSEIQAEQDRkVEEVRDAMENEmRTQLRRQAAAHTDHLRDVlkvqEQELK 427
Cdd:COG4913 357 RERRRArLEALLaalglplpasAEEFAALRAEAAALLEA-LEEELEALEEA-LAEAEAALRDLRRELREL----EAEIA 429
|
|
| HMMR_N |
pfam15905 |
Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of ... |
328-451 |
8.92e-03 |
|
Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of eukaryotic hyaluronan-mediated motility receptor proteins. The protein is functionally associated with BRCA1 and thus predicted to be a common, low-penetrance breast cancer candidate.
Pssm-ID: 464932 [Multi-domain] Cd Length: 329 Bit Score: 39.02 E-value: 8.92e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958769484 328 HAHRRIDQLNRELaqqKATEKQHIELALERQKLEEKRAFDSAVAKALEHHRSEIQaeqdrKVEEVRDAMENEMRTqLRRQ 407
Cdd:pfam15905 195 HSKGKVAQLEEKL---VSTEKEKIEEKSETEKLLEYITELSCVSEQVEKYKLDIA-----QLEELLKEKNDEIES-LKQS 265
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 1958769484 408 AAAHTDHLRDVLKVQEQELKfEFEQDLSEKLSEQELEFHRRSQE 451
Cdd:pfam15905 266 LEEKEQELSKQIKDLNEKCK-LLESEKEELLREYEEKEQTLNAE 308
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
198-392 |
9.11e-03 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 38.37 E-value: 9.11e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958769484 198 VEGALKERRKAVDEAADALLKAKEELEKMKTIIEDAkKREIAgatpyitaaeeKLHSMIVDLDSVVKKVQAAQSEAKVVS 277
Cdd:COG1579 22 LEHRLKELPAELAELEDELAALEARLEAAKTELEDL-EKEIK-----------RLELEIEEVEARIKKYEEQLGNVRNNK 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958769484 278 QYHELvvqarddfRKELDSITPDItpgwkgmsisdlagtlstDDLNALIAHAHRRIDQLNRELAQQKAtekqhiELALER 357
Cdd:COG1579 90 EYEAL--------QKEIESLKRRI------------------SDLEDEILELMERIEELEEELAELEA------ELAELE 137
|
170 180 190
....*....|....*....|....*....|....*.
gi 1958769484 358 QKLEEKRA-FDSAVAKaLEHHRSEIQAEQDRKVEEV 392
Cdd:COG1579 138 AELEEKKAeLDEELAE-LEAELEELEAEREELAAKI 172
|
|
| COG4223 |
COG4223 |
Uncharacterized conserved protein [Function unknown]; |
465-668 |
9.21e-03 |
|
Uncharacterized conserved protein [Function unknown];
Pssm-ID: 443367 [Multi-domain] Cd Length: 259 Bit Score: 38.49 E-value: 9.21e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958769484 465 ARLRGIEQAVQSHAVAEEEARKAHQLWLSVEALKYSMKTSSaemptiPLGSAVEAIRVSCSDNEFTQALTAAippesLTR 544
Cdd:COG4223 67 ARLAALEAKAAAPEAEAAAAARAAALALAAAALRAAVERGQ------PFAAELAALEALAPDAPALAALAAF-----AAT 135
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958769484 545 GVYSEETLRARFYAVQKLAGRVAMIDETKNSLYQYFLSYLQSLLlfppkQLKPPAElyPEDINTFKLLSYASYCIEHGDL 624
Cdd:COG4223 136 GVPTLAALRAEFPAAARAALAAARAPEADASWLDRLLAFARSLV-----TVRRVGP--VEGDDPDAILARAEAALAAGDL 208
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 1958769484 625 ELAAKFVNQLKGESRRVAQDWLKEARMTLETKQIVEILTTYASA 668
Cdd:COG4223 209 AGALAELEALPEAAQAAAAPWIAKAEARLAADAALQALAAQALA 252
|
|
| |
