|
Name |
Accession |
Description |
Interval |
E-value |
| AspB |
COG0436 |
Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]; ... |
8-418 |
4.99e-127 |
|
Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]; Aspartate/methionine/tyrosine aminotransferase is part of the Pathway/BioSystem: Isoleucine, leucine, valine biosynthesis
Pssm-ID: 440205 [Multi-domain] Cd Length: 387 Bit Score: 372.16 E-value: 4.99e-127
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 8 AKRIEGLDQNVWVEFTKL-----AADSSVVNLGQGFPDITLPSYVQEELsKAAFIDNLNQYTRGFGHPSLVKALSCLYGK 82
Cdd:COG0436 4 SSRLARLPPSPIREVSALaaelkAAGEDVIDLGIGEPDFPTPDHIREAA-IEALDDGVTGYTPSAGIPELREAIAAYYKR 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 83 IYQKQIDPnEEILVTVGGYGSLFNAIQGLVDPGDEVIIMVPFYDCYEPMVKMAGAVPVFIPLRSKRtdgmkwtssDWTFN 162
Cdd:COG0436 83 RYGVDLDP-DEILVTNGAKEALALALLALLNPGDEVLVPDPGYPSYRAAVRLAGGKPVPVPLDEEN---------GFLPD 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 163 PQELESKFSSKTKAIILNTPHNPIGKVYTREELQVIADLCIKHDTLCISDEVYEWLVYTGHKHIKIATLPGMWERTITIG 242
Cdd:COG0436 153 PEALEAAITPRTKAIVLNSPNNPTGAVYSREELEALAELAREHDLLVISDEIYEELVYDGAEHVSILSLPGLKDRTIVIN 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 243 SAGKTFSVTGWKLGWSIGPGHLIKHLRTVQQNSVYTCATPLQAALAEAFwidikrmDDPECYFNSLPKELEVKRDRMACL 322
Cdd:COG0436 233 SFSKSYAMTGWRIGYAVGPPELIAALLKLQSNLTSCAPTPAQYAAAAAL-------EGPQDYVEEMRAEYRRRRDLLVEG 305
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 323 LNSVGLKPIIPDGGYFIIADVSSLGVDlsdvksdepyDYKFVKWMTKNKKLSAIPVSAFCdseskPHFEKLVRFCFIKKD 402
Cdd:COG0436 306 LNEIGLSVVKPEGAFYLFADVPELGLD----------SEEFAERLLEEAGVAVVPGSAFG-----PAGEGYVRISYATSE 370
|
410
....*....|....*.
gi 1958752305 403 STLDAAEEIFRTWNSR 418
Cdd:COG0436 371 ERLEEALERLARFLER 386
|
|
| PRK07777 |
PRK07777 |
putative succinyldiaminopimelate transaminase DapC; |
10-418 |
4.35e-124 |
|
putative succinyldiaminopimelate transaminase DapC;
Pssm-ID: 236095 [Multi-domain] Cd Length: 387 Bit Score: 364.74 E-value: 4.35e-124
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 10 RIEGLDQNVWVEFTKLAADSSVVNLGQGFPDITLPSYVQEELSKAaFIDNLNQYTRGFGHPSLVKALSCLYGKIYQKQID 89
Cdd:PRK07777 5 RLRPFGTTIFAEMSALAVRTGAVNLGQGFPDEDGPPEMLEAAQEA-IAGGVNQYPPGPGIPELRAAIAAQRRRRYGLEYD 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 90 PNEEILVTVGGYGSLFNAIQGLVDPGDEVIIMVPFYDCYEPMVKMAGAVPVFIPLRSkrtdgmkwTSSDWTFNPQELESK 169
Cdd:PRK07777 84 PDTEVLVTVGATEAIAAAVLGLVEPGDEVLLIEPYYDSYAAVIAMAGAHRVPVPLVP--------DGRGFALDLDALRAA 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 170 FSSKTKAIILNTPHNPIGKVYTREELQVIADLCIKHDTLCISDEVYEWLVYTGHKHIKIATLPGMWERTITIGSAGKTFS 249
Cdd:PRK07777 156 VTPRTRALIVNSPHNPTGTVLTAAELAAIAELAVEHDLLVITDEVYEHLVFDGARHLPLATLPGMRERTVTISSAAKTFN 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 250 VTGWKLGWSIGPGHLIKHLRTVQQNSVYTCATPLQAALAEAfwidikrMDDPECYFNSLPKELEVKRDRMACLLNSVGLK 329
Cdd:PRK07777 236 VTGWKIGWACGPAPLIAAVRAAKQYLTYVGGAPFQPAVAHA-------LDHEDAWVAALRDSLQAKRDRLAAGLAEAGFE 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 330 PIIPDGGYFIIADVSSLGVDLSdvksdepydYKFVKWMTKNKKLSAIPVSAFCDSESkpHFEKLVRFCFIKKDSTLDAAE 409
Cdd:PRK07777 309 VHDSAGTYFLCADPRPLGYDDG---------TEFCRALPERVGVAAIPMSVFYDPAD--AWNHLVRFAFCKRDDTLDEAI 377
|
....*....
gi 1958752305 410 EIFRTWNSR 418
Cdd:PRK07777 378 RRLRALRGR 386
|
|
| PRK08912 |
PRK08912 |
aminotransferase; |
25-418 |
5.23e-124 |
|
aminotransferase;
Pssm-ID: 181580 Cd Length: 387 Bit Score: 364.30 E-value: 5.23e-124
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 25 LAADSSVVNLGQGFPDITLPSYVQEELSkAAFIDNLNQYTRGFGHPSLVKALSCLYGKIYQKQIDPNEEILVTVGGYGSL 104
Cdd:PRK08912 22 LAREHGAINLGQGFPDDPGPEDVRRAAA-DALLDGSNQYPPMMGLPELRQAVAAHYARFQGLDLDPETEVMVTSGATEAL 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 105 FNAIQGLVDPGDEVIIMVPFYDCYEPMVKMAGAVPVFIPLrskrtdgmkwTSSDWTFNPQELESKFSSKTKAIILNTPHN 184
Cdd:PRK08912 101 AAALLALVEPGDEVVLFQPLYDAYLPLIRRAGGVPRLVRL----------EPPHWRLPRAALAAAFSPRTKAVLLNNPLN 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 185 PIGKVYTREELQVIADLCIKHDTLCISDEVYEWLVYTGHKHIKIATLPGMWERTITIGSAGKTFSVTGWKLGWSIGPGHL 264
Cdd:PRK08912 171 PAGKVFPREELALLAEFCQRHDAVAICDEVWEHVVFDGRRHIPLMTLPGMRERTVKIGSAGKIFSLTGWKVGFVCAAPPL 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 265 IKHLRTVQQNSVYTCATPLQAALAEAfwidikrMDDPECYFNSLPKELEVKRDRMACLLNSVGLkPIIPDGG-YFIIADV 343
Cdd:PRK08912 251 LRVLAKAHQFLTFTTPPNLQAAVAYG-------LGKPDDYFEGMRADLARSRDRLAAGLRRIGF-PVLPSQGtYFLTVDL 322
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1958752305 344 SSLGVDLSDVksdepydyKFVKWMTKNKKLSAIPVSAFCDSESKPHfekLVRFCFIKKDSTLDAAEEIFRTWNSR 418
Cdd:PRK08912 323 APLGLAEDDV--------AFCRRLVEEAGVAAIPVSAFYEEDPVTS---VVRFCFAKRDATLDEAVERLAAARRR 386
|
|
| PLN00175 |
PLN00175 |
aminotransferase family protein; Provisional |
8-414 |
1.40e-111 |
|
aminotransferase family protein; Provisional
Pssm-ID: 215089 [Multi-domain] Cd Length: 413 Bit Score: 333.75 E-value: 1.40e-111
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 8 AKRIEGLDQNVWVEFTKLAADSSVVNLGQGFPDITLPSYVQEElSKAAFIDNLNQYTRGFGHPSLVKALSCLYGKIYQKQ 87
Cdd:PLN00175 33 AKRLEKFKTTIFTQMSSLAIKHGAINLGQGFPNFDGPDFVKEA-AIQAIRDGKNQYARGFGVPELNSAIAERFKKDTGLV 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 88 IDPNEEILVTVGGYGSLFNAIQGLVDPGDEVIIMVPFYDCYEPMVKMAGAVPVFIPLRSKrtdgmkwtssDWTFNPQELE 167
Cdd:PLN00175 112 VDPEKEVTVTSGCTEAIAATILGLINPGDEVILFAPFYDSYEATLSMAGAKIKTVTLRPP----------DFAVPEDELK 181
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 168 SKFSSKTKAIILNTPHNPIGKVYTREELQVIADLCIKHDTLCISDEVYEWLVYTGhKHIKIATLPGMWERTITIGSAGKT 247
Cdd:PLN00175 182 AAFTSKTRAILINTPHNPTGKMFTREELELIASLCKENDVLAFTDEVYDKLAFEG-DHISMASLPGMYERTVTMNSLGKT 260
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 248 FSVTGWKLGWSIGPGHLIKHLRTVQQNSVYTCATPLQAALAEAfwidikrMDDPECYFNSLPKELEVKRDRMACLLNSVG 327
Cdd:PLN00175 261 FSLTGWKIGWAIAPPHLTWGVRQAHSFLTFATATPMQWAAVAA-------LRAPESYYEELKRDYSAKKDILVEGLKEVG 333
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 328 LKPIIPDGGYFIIADVSSLGVDlsdvksdepYDYKFVKWMTKNKKLSAIPVSAF-CDSESKPHfekLVRFCFIKKDSTLD 406
Cdd:PLN00175 334 FKVYPSSGTYFVMVDHTPFGFE---------NDIAFCEYLIEEVGVAAIPPSVFyLNPEDGKN---LVRFAFCKDEETLR 401
|
....*...
gi 1958752305 407 AAEEIFRT 414
Cdd:PLN00175 402 AAVERMKT 409
|
|
| PRK09082 |
PRK09082 |
methionine aminotransferase; Validated |
22-410 |
2.96e-106 |
|
methionine aminotransferase; Validated
Pssm-ID: 181642 [Multi-domain] Cd Length: 386 Bit Score: 319.17 E-value: 2.96e-106
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 22 FT---KLAADSSVVNLGQGFPDITLPSYVQEELSKAAfIDNLNQYTRGFGHPSLVKALSCLYGKIYQKQIDPNEEILVTV 98
Cdd:PRK09082 20 FTvmsALAAEHGAINLSQGFPDFDGPPYLVEALAYAM-AAGHNQYPPMTGVAALREAIAAKTARLYGRQYDADSEITVTA 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 99 GGYGSLFNAIQGLVDPGDEVIIMVPFYDCYEPMVKMAGAVPVFIPLRSKrtdgmkwtssdwTFNP--QELESKFSSKTKA 176
Cdd:PRK09082 99 GATEALFAAILALVRPGDEVIVFDPSYDSYAPAIELAGGRAVRVALQPP------------DFRVdwQRFAAAISPRTRL 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 177 IILNTPHNPIGKVYTREELQVIADLCIKHDTLCISDEVYEWLVYTGHKHIKIATLPGMWERTITIGSAGKTFSVTGWKLG 256
Cdd:PRK09082 167 IILNTPHNPSGTVWSAADMRALWQLIAGTDIYVLSDEVYEHIVFDGAGHASVLRHPELRERAFVVSSFGKTYHVTGWKVG 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 257 WSIGPGHLIKHLRTVQQNSVYTCATPLQAALAEAFwidikrMDDPECYfNSLPKELEVKRDRMACLLNSVGLKPIIPDGG 336
Cdd:PRK09082 247 YCVAPAALSAEFRKVHQYNTFTVNTPAQLALADYL------RAEPEHY-LELPAFYQAKRDRFRAALANSRFKLLPCEGT 319
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1958752305 337 YFIIADVSSLGvDLSDVksdepydyKFVKWMTKNKKLSAIPVSAFCDSeskPHFEKLVRFCFIKKDSTLDAAEE 410
Cdd:PRK09082 320 YFQLVDYSAIS-DLDDV--------EFCQWLTREHGVAAIPLSVFYAD---PFPHRLVRLCFAKQEETLDAAAE 381
|
|
| AAT_like |
cd00609 |
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent ... |
32-413 |
1.39e-94 |
|
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. The major groups in this CD corresponds to Aspartate aminotransferase a, b and c, Tyrosine, Alanine, Aromatic-amino-acid, Glutamine phenylpyruvate, 1-Aminocyclopropane-1-carboxylate synthase, Histidinol-phosphate, gene products of malY and cobC, Valine-pyruvate aminotransferase and Rhizopine catabolism regulatory protein.
Pssm-ID: 99734 [Multi-domain] Cd Length: 350 Bit Score: 288.09 E-value: 1.39e-94
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 32 VNLGQGFPDITLPSYVQEELSKAAFIDNLNQYTRGFGHPSLVKALSCLYGKIYQKQIDPnEEILVTVGGYGSLFNAIQGL 111
Cdd:cd00609 1 IDLSIGEPDFPPPPEVLEALAAAALRAGLLGYYPDPGLPELREAIAEWLGRRGGVDVPP-EEIVVTNGAQEALSLLLRAL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 112 VDPGDEVIIMVPFYDCYEPMVKMAGAVPVFIPLRSkrtDGMkwtssdWTFNPQELESKFSSKTKAIILNTPHNPIGKVYT 191
Cdd:cd00609 80 LNPGDEVLVPDPTYPGYEAAARLAGAEVVPVPLDE---EGG------FLLDLELLEAAKTPKTKLLYLNNPNNPTGAVLS 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 192 REELQVIADLCIKHDTLCISDEVYEWLVYTGHKHIkIATLPGMWERTITIGSAGKTFSVTGWKLGWSIGP-GHLIKHLRT 270
Cdd:cd00609 151 EEELEELAELAKKHGILIISDEAYAELVYDGEPPP-ALALLDAYERVIVLRSFSKTFGLPGLRIGYLIAPpEELLERLKK 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 271 VQQNSVYTCATPLQAALAEAfwidikrMDDPECYFNSLPKELEVKRDRMACLLNSVG-LKPIIPDGGYFIIADVSslgvd 349
Cdd:cd00609 230 LLPYTTSGPSTLSQAAAAAA-------LDDGEEHLEELRERYRRRRDALLEALKELGpLVVVKPSGGFFLWLDLP----- 297
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1958752305 350 lsdvksdEPYDYKFVKWMTKNKKLSAIPVSAFCdsESKPHFeklVRFCFIKKDSTLDAAEEIFR 413
Cdd:cd00609 298 -------EGDDEEFLERLLLEAGVVVRPGSAFG--EGGEGF---VRLSFATPEEELEEALERLA 349
|
|
| PRK05764 |
PRK05764 |
aspartate aminotransferase; Provisional |
31-381 |
1.18e-89 |
|
aspartate aminotransferase; Provisional
Pssm-ID: 235596 Cd Length: 393 Bit Score: 276.62 E-value: 1.18e-89
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 31 VVNLGQGFPDITLPSYVQEElSKAAFIDNLNQYTRGFGHPSLVKALSCLYGKIYQKQIDPnEEILVTVGGYGSLFNAIQG 110
Cdd:PRK05764 33 VISLGAGEPDFDTPEHIKEA-AIEALDDGKTKYTPAAGIPELREAIAAKLKRDNGLDYDP-SQVIVTTGAKQALYNAFMA 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 111 LVDPGDEVIIMVPFYDCYEPMVKMAGAVPVFIPLRSkrTDGMKWTssdwtfnPQELESKFSSKTKAIILNTPHNPIGKVY 190
Cdd:PRK05764 111 LLDPGDEVIIPAPYWVSYPEMVKLAGGVPVFVPTGE--ENGFKLT-------VEQLEAAITPKTKALILNSPSNPTGAVY 181
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 191 TREELQVIADLCIKHDTLCISDEVYEWLVYTGHKHIKIATL-PGMWERTITIGSAGKTFSVTGWKLGWSIGPGHLIKHLR 269
Cdd:PRK05764 182 SPEELEAIADVAVEHDIWVLSDEIYEKLVYDGAEFTSIASLsPELRDRTITVNGFSKAYAMTGWRLGYAAGPKELIKAMS 261
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 270 TVQQNSvYTCATPL-QAALAEAF---WIDIKRMDdpecyfnslpKELEVKRDRMACLLNSV-GLKPIIPDGGYFIIADVS 344
Cdd:PRK05764 262 KLQSHS-TSNPTSIaQYAAVAALngpQDEVEEMR----------QAFEERRDLMVDGLNEIpGLECPKPEGAFYVFPNVS 330
|
330 340 350
....*....|....*....|....*....|....*..
gi 1958752305 345 SLGvdlsdvKSDEPYDYKFVKWMTKNKKLSAIPVSAF 381
Cdd:PRK05764 331 KLL------GKSITDSLEFAEALLEEAGVAVVPGIAF 361
|
|
| PRK12414 |
PRK12414 |
putative aminotransferase; Provisional |
24-405 |
8.86e-70 |
|
putative aminotransferase; Provisional
Pssm-ID: 183514 Cd Length: 384 Bit Score: 225.44 E-value: 8.86e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 24 KLAADSSVVNLGQGFPDITLPSYVQEELSKAaFIDNLNQYTRGFGHPSLVKALSCLYGKIYQKQIDPNEEILVTVGGYGS 103
Cdd:PRK12414 24 QLAAQHDALNLSQGAPNFAPDPALVEGVARA-MRDGHNQYAPMAGIAALREALAEKTERLYGARYDPASEVTVIASASEG 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 104 LFNAIQGLVDPGDEVIIMVPFYDCYEPMVKMAGAVPVFIplrskrtdgmKWTSSDWTFNPQELESKFSSKTKAIILNTPH 183
Cdd:PRK12414 103 LYAAISALVHPGDEVIYFEPSFDSYAPIVRLQGATPVAI----------KLSPEDFRVNWDEVAAAITPRTRMIIVNTPH 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 184 NPIGKVYTREELQVIADLCIKHDTLCISDEVYEWLVYTGHKHIKIATLPGMWERTITIGSAGKTFSVTGWKLGWSIGPGH 263
Cdd:PRK12414 173 NPSATVFSAADLARLAQLTRNTDIVILSDEVYEHVVFDGARHHSMARHRELAERSVIVSSFGKSYHVTGWRVGYCLAPAE 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 264 LIKHLRTVQQNSVYTCATPLQAALAEAfwidikrMDDPECYFnSLPKELEVKRDRMACLLNSVGLKPIIPDGGYFIIADV 343
Cdd:PRK12414 253 LMDEIRKVHQFMVFSADTPMQHAFAEA-------LAEPASYL-GLGAFYQRKRDLLARELAGSRFELLPSEGSFFMLARF 324
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1958752305 344 SSLgvdlsdvkSDEPyDYKFVKWMTKNKKLSAIPVSAFCDSESKphfEKLVRFCFIKKDSTL 405
Cdd:PRK12414 325 RHF--------SDES-DSDFVLRLIRDARVATIPLSAFYTDGTD---TGLIRLSFSKDDATL 374
|
|
| PRK07683 |
PRK07683 |
aminotransferase A; Validated |
21-381 |
3.65e-60 |
|
aminotransferase A; Validated
Pssm-ID: 236075 Cd Length: 387 Bit Score: 200.34 E-value: 3.65e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 21 EFTKLAAD-SSVVNLGQGFPDITLPSYVQEElSKAAFIDNLNQYTRGFGHPSLVKALSCLYGKIYQKQIDPNEEILVTVG 99
Cdd:PRK07683 19 QFSNMVQNyDNLISLTIGQPDFPTPSHVKEA-AKRAITENYTSYTHNAGLLELRKAACNFVKDKYDLHYSPESEIIVTIG 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 100 GYGSLFNAIQGLVDPGDEVIIMVPFYDCYEPMVKMAGAVPVFIPLRskrtdgmkwtSSDWTFNPQELESKFSSKTKAIIL 179
Cdd:PRK07683 98 ASEAIDIAFRTILEPGTEVILPAPIYPGYEPIIRLCGAKPVFIDTR----------STGFRLTAEALENAITEKTRCVVL 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 180 NTPHNPIGKVYTREELQVIADLCIKHDTLCISDEVYEWLVYTGhKHIKIATLPGMWERTITIGSAGKTFSVTGWKLGWSI 259
Cdd:PRK07683 168 PYPSNPTGVTLSKEELQDIADVLKDKNIFVLSDEIYSELVYEQ-PHTSIAHFPEMREKTIVINGLSKSHSMTGWRIGFLF 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 260 GPGHLIKHLRTVQQNSVyTCATPL-QAALAEAFWIDIkrmDDPECYFNSLPKELEVKRDRmaclLNSVGLKPIIPDGGYF 338
Cdd:PRK07683 247 APSYLAKHILKVHQYNV-TCASSIsQYAALEALTAGK---DDAKMMRHQYKKRRDYVYNR----LISMGLDVEKPTGAFY 318
|
330 340 350 360
....*....|....*....|....*....|....*....|...
gi 1958752305 339 IIADVSSLGVDlsdvksdepyDYKFVKWMTKNKKLSAIPVSAF 381
Cdd:PRK07683 319 LFPSIGHFTMS----------SFDFALDLVEEAGLAVVPGSAF 351
|
|
| PRK06348 |
PRK06348 |
pyridoxal phosphate-dependent aminotransferase; |
8-381 |
1.03e-57 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 180537 Cd Length: 384 Bit Score: 193.78 E-value: 1.03e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 8 AKRIEGLDQNVWVEFTKLAAD-SSVVNLGQGFPDITlpsyVQEELSKAAFIDNLNQYTR---GFGHPSLVKALSCLYGKI 83
Cdd:PRK06348 7 AKKYQQMEVNIMAEIATLAKKfPDIIDLSLGDPDLI----TDESIINAAFEDAKKGHTRytdSGGDVELIEEIIKYYSKN 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 84 YQKQIDPNEeILVTVGGYGSLFNAIQGLVDPGDEVIIMVPFYDCYEPMVKMAGAVPVFIPLRSKrtdgmkwtsSDWTFNP 163
Cdd:PRK06348 83 YDLSFKRNE-IMATVGACHGMYLALQSILDPGDEVIIHEPYFTPYKDQIEMVGGKPIILETYEE---------DGFQINV 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 164 QELESKFSSKTKAIILNTPHNPIGKVYTREELQVIADLCIKHDTLCISDEVYEWLVYTgHKHIKIATLPGMWERTITIGS 243
Cdd:PRK06348 153 KKLEALITSKTKAIILNSPNNPTGAVFSKETLEEIAKIAIEYDLFIISDEVYDGFSFY-EDFVPMATLAGMPERTITFGS 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 244 AGKTFSVTGWKLGWSIGPGHLIKHLRTVQQNSVYTCATPLQAALAEAFwidikRMDDpecyfNSLPKELEVKRDRMACLL 323
Cdd:PRK06348 232 FSKDFAMTGWRIGYVIAPDYIIETAKIINEGICFSAPTISQRAAIYAL-----KHRD-----TIVPLIKEEFQKRLEYAY 301
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1958752305 324 NSVGLKP----IIPDGGYFIIADVSSLGvdLSDVksdepydyKFVKWMTKNKKLSAIPVSAF 381
Cdd:PRK06348 302 KRIESIPnlslHPPKGSIYAFINIKKTG--LSSV--------EFCEKLLKEAHVLVIPGKAF 353
|
|
| PRK07682 |
PRK07682 |
aminotransferase; |
22-384 |
1.06e-57 |
|
aminotransferase;
Pssm-ID: 181082 [Multi-domain] Cd Length: 378 Bit Score: 193.41 E-value: 1.06e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 22 FTKLAAD-SSVVNLGQGFPDITLPSYVQEelskaAFIDNLNQ----YTRGFGHPSLVKALSCLYGKIYQKQIDPNEEILV 96
Cdd:PRK07682 12 FFDLAANmEGVISLGVGEPDFVTPWNVRE-----ASIRSLEQgytsYTANAGLLELRQEIAKYLKKRFAVSYDPNDEIIV 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 97 TVGGYGSLFNAIQGLVDPGDEVIIMVPFYDCYEPMVKMAGAVPVfiPLRSKRTDGMKwtssdwtFNPQELESKFSSKTKA 176
Cdd:PRK07682 87 TVGASQALDVAMRAIINPGDEVLIVEPSFVSYAPLVTLAGGVPV--PVATTLENEFK-------VQPAQIEAAITAKTKA 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 177 IILNTPHNPIGKVYTREELQVIADLCIKHDTLCISDEVYEWLVYTGhKHIKIATLPGMWERTITIGSAGKTFSVTGWKLG 256
Cdd:PRK07682 158 ILLCSPNNPTGAVLNKSELEEIAVIVEKHDLIVLSDEIYAELTYDE-AYTSFASIKGMRERTILISGFSKGFAMTGWRLG 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 257 WSIGPGHLIKHLRTVQQNSVYTCATPLQAALAEAFWidiKRMDDPECYFNSLPKelevKRDRMACLLNSVGLKPIIPDGG 336
Cdd:PRK07682 237 FIAAPVYFSEAMLKIHQYSMMCAPTMAQFAALEALR---AGNDDVIRMRDSYRK----RRNFFVTSFNEIGLTCHVPGGA 309
|
330 340 350 360
....*....|....*....|....*....|....*....|....*...
gi 1958752305 337 YFIIADVSSLGvdlsdVKSDEpydykFVKWMTKNKKLSAIPVSAFCDS 384
Cdd:PRK07682 310 FYAFPSISSTG-----LSSEE-----FAEQLLLEEKVAVVPGSVFGES 347
|
|
| PRK07309 |
PRK07309 |
pyridoxal phosphate-dependent aminotransferase; |
31-381 |
3.47e-56 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 235985 Cd Length: 391 Bit Score: 189.94 E-value: 3.47e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 31 VVNLGQGFPDITLPSYVQEElSKAAFIDNLNQYTRGFGHPSLVKALSCLYGKIYQKQIDPNEEILVTVGGYGSLFNAIQG 110
Cdd:PRK07309 32 ILKLTLGEPDFTTPDHVKEA-AKRAIDANQSHYTGMAGLLELRQAAADFVKEKYNLDYAPENEILVTIGATEALSASLTA 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 111 LVDPGDEVIIMVPFYDCYEPMVKMAGAVPVFiplrskrtdgMKWTSSDWTFNPQELESKFSS---KTKAIILNTPHNPIG 187
Cdd:PRK07309 111 ILEPGDKVLLPAPAYPGYEPIVNLVGAEIVE----------IDTTENDFVLTPEMLEKAILEqgdKLKAVILNYPANPTG 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 188 KVYTREELQVIADLCIKHDTLCISDEVYEWLVYTGHKHIKIAT-LPgmwERTITIGSAGKTFSVTGWKLGWSIGPGHLIK 266
Cdd:PRK07309 181 VTYSREQIKALADVLKKYDIFVISDEVYSELTYTGEPHVSIAEyLP---DQTILINGLSKSHAMTGWRIGLIFAPAEFTA 257
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 267 HLRTVQQNSVYTCATPLQAALAEAFwidIKRMDDPEcyfnSLPKELEVKRDRMACLLNSVGLKPIIPDGGYFIIADV-SS 345
Cdd:PRK07309 258 QLIKSHQYLVTAATTMAQFAAVEAL---TNGKDDAL----PMKKEYIKRRDYIIEKMTDLGFKIIKPDGAFYIFAKIpAG 330
|
330 340 350
....*....|....*....|....*....|....*.
gi 1958752305 346 LGVDlsdvksdepyDYKFVKWMTKNKKLSAIPVSAF 381
Cdd:PRK07309 331 YNQD----------SFKFLQDFARKKAVAFIPGAAF 356
|
|
| Aminotran_1_2 |
pfam00155 |
Aminotransferase class I and II; |
31-346 |
1.60e-51 |
|
Aminotransferase class I and II;
Pssm-ID: 395103 [Multi-domain] Cd Length: 351 Bit Score: 176.73 E-value: 1.60e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 31 VVNLGQG-FPDITLPSYVQEELSKAAFiDNLNQYTRGFGHPSLVKALSCLYGKIYQKQIDPNEEILVTVGGYGSLFNAIQ 109
Cdd:pfam00155 3 KINLGSNeYLGDTLPAVAKAEKDALAG-GTRNLYGPTDGHPELREALAKFLGRSPVLKLDREAAVVFGSGAGANIEALIF 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 110 GLVDPGDEVIIMVPFYDCYEPMVKMAGAVPVFIPLRSkrtdgmkwtSSDWTFNPQELESKFSSKTKAIILNTPHNPIGKV 189
Cdd:pfam00155 82 LLANPGDAILVPAPTYASYIRIARLAGGEVVRYPLYD---------SNDFHLDFDALEAALKEKPKVVLHTSPHNPTGTV 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 190 YTREELQVIADLCIKHDTLCISDEVYEWLVYTGHKHIKIATL--PGMWerTITIGSAGKTFSVTGWKLGWSIGPGHLIKH 267
Cdd:pfam00155 153 ATLEELEKLLDLAKEHNILLLVDEAYAGFVFGSPDAVATRALlaEGPN--LLVVGSFSKAFGLAGWRVGYILGNAAVISQ 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 268 LRTVqQNSVYTCaTPLQAALAEAfwidikrMDDPE---CYFNSLPKELEVKRDRMACLLNSVGLKPIIPDGGYFIIADVS 344
Cdd:pfam00155 231 LRKL-ARPFYSS-THLQAAAAAA-------LSDPLlvaSELEEMRQRIKERRDYLRDGLQAAGLSVLPSQAGFFLLTGLD 301
|
..
gi 1958752305 345 SL 346
Cdd:pfam00155 302 PE 303
|
|
| PRK07568 |
PRK07568 |
pyridoxal phosphate-dependent aminotransferase; |
33-419 |
1.46e-50 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 181036 Cd Length: 397 Bit Score: 175.43 E-value: 1.46e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 33 NLGQgfPDITLPSYVQEELSKAAFidNLNQYTRGFGHPSLVKALSclygKIYQKQ---IDPnEEILVTVGGYGSLFNAIQ 109
Cdd:PRK07568 36 NIGQ--PDIKTPEVFFEAIKNYDE--EVLAYSHSQGIPELREAFA----KYYKKWgidVEP-DEILITNGGSEAILFAMM 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 110 GLVDPGDEVIIMVPFYDCYEPMVKMAGAVPVfiPLRSKRTDGmkwtssdwtF---NPQELESKFSSKTKAIILNTPHNPI 186
Cdd:PRK07568 107 AICDPGDEILVPEPFYANYNGFATSAGVKIV--PVTTKIEEG---------FhlpSKEEIEKLITPKTKAILISNPGNPT 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 187 GKVYTREELQVIADLCIKHDTLCISDEVYEWLVYTGHKHIKIATLPGMWERTITIGSAGKTFSVTGWKLGWsigpghLIK 266
Cdd:PRK07568 176 GVVYTKEELEMLAEIAKKHDLFLISDEVYREFVYDGLKYTSALSLEGLEDRVIIIDSVSKRYSACGARIGC------LIS 249
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 267 HLRTVQQNSVYTC------ATPLQAALAEAfwidikrMDDPECYFNSLPKELEVKRDRMACLLNSV-GLKPIIPDGGYFI 339
Cdd:PRK07568 250 KNKELIAAAMKLCqarlspPTLEQIGAAAL-------LDTPESYFDEVREEYKKRRDILYEELNKIpGVVCEKPKGAFYI 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 340 IAdvsSLGVDLSDvksdepydyKFVKWMTK-----NKKLSAIPVSAFCDSESKPHFEklVRFCFIKKDSTLDAAEEIFR- 413
Cdd:PRK07568 323 IA---KLPVDDAE---------DFAKWLLTdfnynGETVMVAPASGFYATPGLGKNE--IRIAYVLNEEDLKRAMEILKe 388
|
....*....
gi 1958752305 414 ---TWNSRK 419
Cdd:PRK07568 389 aleKYNKRK 397
|
|
| PRK08361 |
PRK08361 |
aspartate aminotransferase; Provisional |
22-411 |
1.23e-49 |
|
aspartate aminotransferase; Provisional
Pssm-ID: 236248 [Multi-domain] Cd Length: 391 Bit Score: 172.75 E-value: 1.23e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 22 FTKLAADSSVVNLGQGFPDITLPSYVQEElSKAAFIDNLNQYTRGFGHPSLVKALSCLYGKIYQKQIDPnEEILVTVGGY 101
Cdd:PRK08361 26 FERASKMENVISLGIGEPDFDTPKNIKEA-AKRALDEGWTHYTPNAGIPELREAIAEYYKKFYGVDVDV-DNVIVTAGAY 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 102 GSLFNAIQGLVDPGDEVIIMVPFYDCYEPMVKMAGAVPVFIPLRSKrtdgmkwtsSDWTFNPQELESKFSSKTKAIILNT 181
Cdd:PRK08361 104 EATYLAFESLLEEGDEVIIPDPAFVCYVEDAKIAEAKPIRIPLREE---------NEFQPDPDELLELITKRTRMIVINY 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 182 PHNPIGKVYTREELQVIADLCIKHDTLCISDEVYEWLVYTGHKH---IKIATlpgmwERTITIGSAGKTFSVTGWKLGWS 258
Cdd:PRK08361 175 PNNPTGATLDKEVAKAIADIAEDYNIYILSDEPYEHFLYEGAKHypmIKYAP-----DNTILANSFSKTFAMTGWRLGFV 249
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 259 IGPGHLIKHLRTVQQNSVYTCATPLQAALAEAF-----WIDIKRMDdpecyfnslpKELEVKRDRMACLLNSV-GLKPII 332
Cdd:PRK08361 250 IAPEQVIKDMIKLHAYIIGNVASFVQIAGIEALrskesWKAVEEMR----------KEYNERRKLVLKRLKEMpHIKVFE 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 333 PDGGYFIIADVSSLGVdlsdvkSDEpydyKFVKWMTKNKKLSAIPVSAFcdsesKPHFEKLVRFCF-IKKDSTLDAAEEI 411
Cdd:PRK08361 320 PKGAFYVFANIDETGM------SSE----DFAEWLLEKARVVVIPGTAF-----GKAGEGYIRISYaTSKEKLIEAMERM 384
|
|
| PRK06107 |
PRK06107 |
aspartate transaminase; |
26-339 |
3.01e-46 |
|
aspartate transaminase;
Pssm-ID: 180403 Cd Length: 402 Bit Score: 164.14 E-value: 3.01e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 26 AADSSVVNLGQGFPDITLPSYVQEELSkAAFIDNLNQYTRGFGHPSLVKALSCLYGKIYQKQIDPNEeILVTVGGYGSLF 105
Cdd:PRK06107 30 AAGRSIVDLTVGEPDFDTPDHIKQAAV-AAIERGETKYTLVNGTPALRKAIIAKLERRNGLHYADNE-ITVGGGAKQAIF 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 106 NAIQGLVDPGDEVIIMVPFYDCYEPMVKMAGAVPVFIPlrSKRTDGMKWTssdwtfnPQELESKFSSKTKAIILNTPHNP 185
Cdd:PRK06107 108 LALMATLEAGDEVIIPAPYWVSYPDMVLANDGTPVIVA--CPEEQGFKLT-------PEALEAAITPRTRWLILNAPSNP 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 186 IGKVYTREELQVIADLCIKH-DTLCISDEVYEWLVYTGHK--HIkIATLPGMWERTITIGSAGKTFSVTGWKLGWSIGPG 262
Cdd:PRK06107 179 TGAVYSRAELRALADVLLRHpHVLVLTDDIYDHIRFDDEPtpHL-LAAAPELRDRVLVTNGVSKTYAMTGWRIGYAAGPA 257
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1958752305 263 HLIKHLRTVQQNSVYTCATPLQAALAEAFWIDikrmddpECYFNSLPKELEVKRDRMACLLNSV-GLKPIIPDGGYFI 339
Cdd:PRK06107 258 DLIAAINKLQSQSSSCPSSISQAAAAAALNGD-------QSFVTESVAVYKQRRDYALALLNAIpGLSCLVPDGAFYL 328
|
|
| PRK06108 |
PRK06108 |
pyridoxal phosphate-dependent aminotransferase; |
31-415 |
5.44e-43 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 180404 Cd Length: 382 Bit Score: 154.72 E-value: 5.44e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 31 VVNLGQGFPDItLPSYVQE-ELSKAAFI-----DNLNQ----YTRGFGHPSLVKALSCLYGKIYQKQIDPnEEILVTVGG 100
Cdd:PRK06108 16 VANAGRGREGV-LPLWFGEsDLPTPDFIrdaaaAALADgetfYTHNLGIPELREALARYVSRLHGVATPP-ERIAVTSSG 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 101 YGSLFNAIQGLVDPGDEVIIMVPFYDCYEPMVKMAGAVPVFIPLRskrtdgmkWTSSDWTFNPQELESKFSSKTKAIILN 180
Cdd:PRK06108 94 VQALMLAAQALVGPGDEVVAVTPLWPNLVAAPKILGARVVCVPLD--------FGGGGWTLDLDRLLAAITPRTRALFIN 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 181 TPHNPIGKVYTREELQVIADLCIKHDTLCISDEVYEWLVYTGH----KHIKIATlPGmwERTITIGSAGKTFSVTGWKLG 256
Cdd:PRK06108 166 SPNNPTGWTASRDDLRAILAHCRRHGLWIVADEVYERLYYAPGgrapSFLDIAE-PD--DRIIFVNSFSKNWAMTGWRLG 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 257 WSIGPGHLIKHLRTVQQNSVYTCATPLQAALAEAfwidikrMDDPECYFNSLPKELEVKRDRMACLLNSV-GLKPIIPDG 335
Cdd:PRK06108 243 WLVAPPALGQVLEKLIEYNTSCVAQFVQRAAVAA-------LDEGEDFVAELVARLRRSRDHLVDALRALpGVEVAKPDG 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 336 GYFIIADVSslGVDLSdvksdepydYKFVKWMTKNKKLSAIPVSAFcdsesKPHFEKLVRFCFIKKDSTLDAAEEIFRTW 415
Cdd:PRK06108 316 AMYAFFRIP--GVTDS---------LALAKRLVDEAGLGLAPGTAF-----GPGGEGFLRWCFARDPARLDEAVERLRRF 379
|
|
| MalY |
COG1168 |
Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor ... |
63-361 |
4.44e-41 |
|
Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism, General function prediction only];
Pssm-ID: 440782 Cd Length: 387 Bit Score: 149.86 E-value: 4.44e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 63 YTrgFGHPSLVKALSCLYGKIYQKQIDPnEEILVTVGGYGSLFNAIQGLVDPGDEVIIMVPFYDCYEPMVKMAGAVPVFI 142
Cdd:COG1168 62 YT--APPDEYYEAIIDWLKRRHGWEIDP-EWIVFTPGVVPGLALAIRAFTEPGDGVLIQTPVYPPFFKAIENNGRELVEN 138
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 143 PLrsKRTDGmkwtssDWTFNPQELESKFSSKTKAIILNTPHNPIGKVYTREELQVIADLCIKHDTLCISDEVYEWLVYTG 222
Cdd:COG1168 139 PL--ILEDG------RYRIDFDDLEAKLDPGVKLLLLCNPHNPTGRVWTREELERLAELCERHDVLVISDEIHADLVLPG 210
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 223 HKHIKIATL-PGMWERTITIGSAGKTFSVTGWKLGWSIGP-----GHLIKHLRTVQQNSVYTCAtplQAALAEAF----- 291
Cdd:COG1168 211 HKHTPFASLsEEAADRTITLTSPSKTFNLAGLKASYAIIPnpalrARFARALEGLGLPSPNVLG---LVATEAAYregee 287
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1958752305 292 WIDikrmddpecyfnSLPKELEVKRDRMACLLNSV--GLKPIIPDGGYFIIADVSSLGVDlsdvkSDEPYDY 361
Cdd:COG1168 288 WLD------------ELLAYLRGNRDLLAEFLAEHlpGVKVTPPEATYLAWLDCRALGLD-----DEELAEF 342
|
|
| PRK05957 |
PRK05957 |
pyridoxal phosphate-dependent aminotransferase; |
32-272 |
2.00e-40 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 235654 Cd Length: 389 Bit Score: 147.91 E-value: 2.00e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 32 VNLGQGFPDITLPSYVQEELSKAAFIDNLNQYTRGFGHPSLVKALSclyGKIYQK---QIDPNEEILVTVGGYGSLFNAI 108
Cdd:PRK05957 30 ISLGQGVVSYPPPPEAIEALNNFLANPENHKYQAVQGIPPLLEAIT---QKLQQDngiELNNEQAIVVTAGSNMAFMNAI 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 109 QGLVDPGDEVIIMVPFYDCYEPMVKMAGAVPVFIPlrskrtdgmkwTSSDWTFNPQELESKFSSKTKAIILNTPHNPIGK 188
Cdd:PRK05957 107 LAITDPGDEIILNTPYYFNHEMAITMAGCQPILVP-----------TDDNYQLQPEAIEQAITPKTRAIVTISPNNPTGV 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 189 VYTREELQVIADLCIKHDTLCISDEVYEWLVYTGHKHIKIATLPGMWERTITIGSAGKTFSVTGWKLGWSIGPGHLIKHL 268
Cdd:PRK05957 176 VYPEALLRAVNQICAEHGIYHISDEAYEYFTYDGVKHFSPGSIPGSGNHTISLYSLSKAYGFASWRIGYMVIPIHLLEAI 255
|
....
gi 1958752305 269 RTVQ 272
Cdd:PRK05957 256 KKIQ 259
|
|
| PRK07337 |
PRK07337 |
pyridoxal phosphate-dependent aminotransferase; |
6-347 |
2.31e-40 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 180937 Cd Length: 388 Bit Score: 147.90 E-value: 2.31e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 6 KNAKRIEGLDQNVWVEFTKLA-----ADSSVVNLGQGFPDITLPSYVQEELSKAAfIDNLNQYTRGFGHPSLVKALSCLY 80
Cdd:PRK07337 2 RLAARVDAIEPFYVMELAKEAqalerAGRDIIHMGIGEPDFTAPEPVVEAAARAL-RRGVTQYTSALGLAPLREAIAAWY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 81 GKIYQKQIDPnEEILVTVGGYGSLFNAIQGLVDPGDEVIIMVPFYDCYEPMVKMAGAVPVFIPlrskrtdgmkwTSSDWT 160
Cdd:PRK07337 81 ARRFGLDVAP-ERIVVTAGASAALLLACLALVERGDEVLMPDPSYPCNRHFVAAAEGRPVLVP-----------SGPAER 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 161 F--NPQELESKFSSKTKAIILNTPHNPIGKVYTREELQVIADLCIKHDTLCISDEVYEWLVYTGHKHIKIAtlpgMWERT 238
Cdd:PRK07337 149 FqlTAADVEAAWGERTRGVLLASPSNPTGTSIAPDELRRIVEAVRARGGFTIVDEIYQGLSYDAAPVSALS----LGDDV 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 239 ITIGSAGKTFSVTGWKLGWSIGPGHLIKHLRTVQQNsVYTCATPL--QAALA----EAFWIDIKRMDdpecyfnslpkEL 312
Cdd:PRK07337 225 ITINSFSKYFNMTGWRLGWLVVPEALVGTFEKLAQN-LFICASALaqHAALAcfepDTLAIYERRRA-----------EF 292
|
330 340 350
....*....|....*....|....*....|....*.
gi 1958752305 313 EVKRDRMACLLNSVGLK-PIIPDGGYFIIADVSSLG 347
Cdd:PRK07337 293 KRRRDFIVPALESLGFKvPVMPDGAFYVYADCRGVA 328
|
|
| C_S_lyase_PatB |
TIGR04350 |
putative C-S lyase; Members of this subfamily are probable C-S lyases from a family of ... |
40-354 |
1.03e-39 |
|
putative C-S lyase; Members of this subfamily are probable C-S lyases from a family of pyridoxal phosphate-dependent enzymes that tend to be (mis)annotated as probable aminotransferases. One member is PatB of Bacillus subtilis, a proven C-S-lyase. Another is the virulence factor cystalysin from Treponema denticola, whose hemolysin activity may stem from H2S production. Members of the seed alignment occur next to examples of the enzyme 5-histidylcysteine sulfoxide synthase, from ovothiol A biosynthesis, and would be expected to perform a C-S cleavage of 5-histidylcysteine sulfoxide to leave 1-methyl-4-mercaptohistidine (ovothiol A).
Pssm-ID: 275146 Cd Length: 384 Bit Score: 145.92 E-value: 1.03e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 40 DITLPSYVQEELSKaafidNLNQYTRGFGHP--SLVKALSCLYGKIYQKQIDPnEEILVTVGGYGSLFNAIQGLVDPGDE 117
Cdd:TIGR04350 36 DFATPPAVLEALKQ-----RLEHPVFGYTLPpdSLYAAVINWLAQRHGWQIDP-EDIVFLPGVVPSLFAAVRALTAPGEG 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 118 VIIMVPFYDCYEPMVKMAGAVPVFIPLrskrtdgmKWTSSDWTFNPQELESKFSSKTKAIILNTPHNPIGKVYTREELQV 197
Cdd:TIGR04350 110 VIVQTPVYPPFLSAVKSNGRELVLNPL--------KLDEGRYRFDLEDLEDAITEKARLLLLCSPHNPVGRVWTREELTR 181
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 198 IADLCIKHDTLCISDEVYEWLVYTGHKHIKIATL-PGMWERTITIGSAGKTFSVTGWKLGWSIGPGH-LIKHLRTVQQNS 275
Cdd:TIGR04350 182 LAELCLRHNVVVVSDEIHADLVYPPNKHIPLASLsPEPAERTVTLLSPGKTFNIAGLNISFAIIPNPeLRRAFQEAAQRV 261
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 276 VYTCATPLQAALAEAFWidikrmDDPECYFNSLPKELEVKRDRMACLLNSV--GLKPIIPDGGYFIIADVSSLGVDLSDV 353
Cdd:TIGR04350 262 HIQHGNLFGYVAFEAAY------RDGEPWLDALLAYLRGNRDLVEEFIAKRlpQIRVRPPEATYLAWLDCRALGLDDADL 335
|
.
gi 1958752305 354 K 354
Cdd:TIGR04350 336 R 336
|
|
| PRK08960 |
PRK08960 |
pyridoxal phosphate-dependent aminotransferase; |
26-349 |
1.81e-39 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 181595 Cd Length: 387 Bit Score: 145.58 E-value: 1.81e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 26 AADSSVVNLGQGFPDITLPSYVQEElSKAAFIDNLNQYTRGFGHPSLVKALSCLYGKIYQKQIDPnEEILVTVGGYGSLF 105
Cdd:PRK08960 29 AAGHDVIHLEIGEPDFTTAEPIVAA-GQAALAAGHTRYTAARGLPALREAIAGFYAQRYGVDVDP-ERILVTPGGSGALL 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 106 NAIQGLVDPGDEVIIMVPFYDCYEPMVKMAGAVPVFIPLRSkrtdgmkwtSSDWTFNPQELESKFSSKTKAIILNTPHNP 185
Cdd:PRK08960 107 LASSLLVDPGKHWLLADPGYPCNRHFLRLVEGAAQLVPVGP---------DSRYQLTPALVERHWNADTVGALVASPANP 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 186 IGKVYTREELQVIADLCIKHDTLCISDEVYEWLVYTghkhIKIATLPGMWERTITIGSAGKTFSVTGWKLGWSIGPGHLI 265
Cdd:PRK08960 178 TGTLLSRDELAALSQALRARGGHLVVDEIYHGLTYG----VDAASVLEVDDDAFVLNSFSKYFGMTGWRLGWLVAPPAAV 253
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 266 KHLRTVQQNsVYTCA-TPLQ-AALAeAFwidikrmdDPECY--FNSLPKELEVKRDRMACLLNSVGLK-PIIPDGGYFII 340
Cdd:PRK08960 254 PELEKLAQN-LYISAsTPAQhAALA-CF--------EPETLaiLEARRAEFARRRDFLLPALRELGFGiAVEPQGAFYLY 323
|
....*....
gi 1958752305 341 ADVSSLGVD 349
Cdd:PRK08960 324 ADISAFGGD 332
|
|
| PRK07681 |
PRK07681 |
LL-diaminopimelate aminotransferase; |
3-411 |
7.42e-36 |
|
LL-diaminopimelate aminotransferase;
Pssm-ID: 181081 Cd Length: 399 Bit Score: 136.09 E-value: 7.42e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 3 LRFKNAKRIEGLDQNVWVEFT-----KLAADSSVVNLGQGFPDITLPSYVQEELSKAAFIDNLNQYTRGfGHPSLVKALS 77
Cdd:PRK07681 1 MTYTLATRMKAFQSSIFSELGaykkeKIAAGHKMIDLSIGNPDMPPADFVREEMVHTANQKESYGYTLS-GIQEFHEAVT 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 78 CLYGKIYQKQIDPNEEILVTVGGYGSLFNAIQGLVDPGDEVIIMVPFYDCYEPMVKMAGAVPVFIPLRSKrtdgmkwtsS 157
Cdd:PRK07681 80 EYYNNTHNVILNADKEVLLLMGSQDGLVHLPMVYANPGDIILVPDPGYTAYETGIQMAGATSYYMPLKKE---------N 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 158 DWTFNPQELESKFSSKTKAIILNTPHNPIGKVYTREELQVIADLCIKHDTLCISDEVYEWLVYTGHKHIKIATLPGMWER 237
Cdd:PRK07681 151 DFLPDLELIPEEIADKAKMMILNFPGNPVPAMAHEDFFKEVIAFAKKHNIIVVHDFAYAEFYFDGNKPISFLSVPGAKEV 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 238 TITIGSAGKTFSVTGWKLGWSIGPGHLIKHLRTVQQNSVYTCATPLQAALAEAFwidikRMDDPECYFNslpKEL-EVKR 316
Cdd:PRK07681 231 GVEINSLSKSYSLAGSRIGYMIGNEEIVRALTQFKSNTDYGVFLPIQKAACAAL-----RNGAAFCEKN---RGIyQERR 302
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 317 DRMACLLNSVGLKPIIPDGGYFIIADVSSLGVDLSdvksdepydykFVKWMTKNKKLSAIPVSAFcdsesKPHFEKLVRF 396
Cdd:PRK07681 303 DTLVDGFRTFGWNVDKPAGSMFVWAEIPKGWTSLS-----------FAYALMDRANVVVTPGHAF-----GPHGEGFVRI 366
|
410
....*....|....*.
gi 1958752305 397 CFIKKDSTL-DAAEEI 411
Cdd:PRK07681 367 ALVQDEEVLqQAVENI 382
|
|
| PRK08363 |
PRK08363 |
alanine aminotransferase; Validated |
31-419 |
1.19e-35 |
|
alanine aminotransferase; Validated
Pssm-ID: 181402 Cd Length: 398 Bit Score: 135.32 E-value: 1.19e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 31 VVNLGQGFP---DITLPSYVQEELSKAaFIDNLNQYTRGFGHPSLVKALSCLYGKIYQKQIDPnEEILVTVGGYGSLFNA 107
Cdd:PRK08363 32 VIRLNIGDPvkfDFQPPEHMKEAYCRA-IKEGHNYYGPSEGLPELREAIVKREKRKNGVDITP-DDVRVTAAVTEALQLI 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 108 IQGLVDPGDEVIIMVPFYDCYEPMVKMAGAVPVFipLRSKRTDGmkwtssdWTFNPQELESKFSSKTKAIILNTPHNPIG 187
Cdd:PRK08363 110 FGALLDPGDEILIPGPSYPPYTGLVKFYGGVPVE--YRTIEEEG-------WQPDIDDIRKKITEKTKAIAVINPNNPTG 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 188 KVYTREELQVIADLCIKHDTLCISDEVYEWLVYTGhKHIKIATLPGMwERTITIGSAGKTFSVTGWKLGWS--IGPGHLI 265
Cdd:PRK08363 181 ALYEKKTLKEILDIAGEHDLPVISDEIYDLMTYEG-KHVSPGSLTKD-VPVIVMNGLSKVYFATGWRLGYIyfVDPEGKL 258
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 266 KHLRTV--QQNSVYTCA-TPLQAALAEAFwidIKRMDdpecYFNSLPKELEVKRDRMACLLNSV-GLKPIIPDGGYFIIA 341
Cdd:PRK08363 259 AEVREAidKLARIRLCPnTPAQFAAIAGL---TGPMD----YLEEYMKKLKERRDYIYKRLNEIpGISTTKPQGAFYIFP 331
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1958752305 342 DvsslgVDLSDVKSDEpydyKFVKWMTKNKKLSAIPVSAFCDSESKpHFeklvRFCFIKKDSTLDAAEEIFRTWNSRK 419
Cdd:PRK08363 332 R-----IEEGPWKDDK----EFVLDVLHEAHVLFVHGSGFGEYGAG-HF----RLVFLPPVEILEEAMDRFEEFMRER 395
|
|
| PRK06836 |
PRK06836 |
pyridoxal phosphate-dependent aminotransferase; |
37-395 |
2.46e-34 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 180720 Cd Length: 394 Bit Score: 131.47 E-value: 2.46e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 37 GFPDITLPSYVQEELSKAAF--IDNLNQYTRGFGHPSLVKALSCLYGKIYQKQIDPnEEILVTVGGYGSLFNAIQGLVDP 114
Cdd:PRK06836 41 GNPSVPPPAAVKEALRELAEeeDPGLHGYMPNAGYPEVREAIAESLNRRFGTPLTA-DHIVMTCGAAGALNVALKAILNP 119
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 115 GDEVIIMVPFYDCYEPMVKMAGAVPVFIPLRSKrtdgmkwtssDWTFNPQELESKFSSKTKAIILNTPHNPIGKVYTREE 194
Cdd:PRK06836 120 GDEVIVFAPYFVEYRFYVDNHGGKLVVVPTDTD----------TFQPDLDALEAAITPKTKAVIINSPNNPTGVVYSEET 189
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 195 LQVIADLC------IKHDTLCISDEVYEWLVYTGhkhIKIATLPGMWERTITIGSAGKTFSVTGWKLGWSI------GPG 262
Cdd:PRK06836 190 LKALAALLeekskeYGRPIYLISDEPYREIVYDG---AEVPYIFKYYDNSIVVYSFSKSLSLPGERIGYIAvnpemeDAD 266
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 263 HLIKHLrtVQQNSV--YTCATPL-QAALAEAfwIDIKRmdDPECYfnslpkelEVKRDRMACLLNSVGLKPIIPDGGYFI 339
Cdd:PRK06836 267 DLVAAL--VFANRIlgFVNAPALmQRVVAKC--LDATV--DVSIY--------KRNRDLLYDGLTELGFECVKPQGAFYL 332
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1958752305 340 IadvsslgvdlsdVKSDEPYDYKFVKwMTKNKKLSAIPVS----------AFCDSE-----SKPHFEKLVR 395
Cdd:PRK06836 333 F------------PKSPEEDDVAFCE-KAKKHNLLLVPGSgfgcpgyfrlSYCVDTetierSLPAFEKLAK 390
|
|
| PRK09276 |
PRK09276 |
LL-diaminopimelate aminotransferase; Provisional |
4-343 |
1.24e-30 |
|
LL-diaminopimelate aminotransferase; Provisional
Pssm-ID: 181749 Cd Length: 385 Bit Score: 121.17 E-value: 1.24e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 4 RFKNAKRIEGLDQNVWVEFTKLAADS-----SVVNLGQGFPDITLPSYVQEELSKAAFIDNLNQYTRGFGHPSLVKALSC 78
Cdd:PRK09276 1 MMKLADRIKNLPPYLFAEIDKKKAEKiargvDVISLGIGDPDLPTPDHIIEAMCKAVEDPENHQYPSYEGMLEFRKAVAD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 79 LYGKIYQKQIDPNEEILVTVG---GYGSLFNAiqgLVDPGDEVIIMVPFYDCYEPMVKMAGAVPVFIPLrsKRTDGMKwt 155
Cdd:PRK09276 81 WYKRRFGVELDPETEVISLIGskeGIAHIPLA---FVNPGDVVLVPDPGYPVYKIGTIFAGGEPYFMPL--KEENGFL-- 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 156 sSDWTFNPQELeskfSSKTKAIILNTPHNPIGKVYTREELQVIADLCIKHDTLCISDEVYEWLVYTGHKHIKIATLPGMW 235
Cdd:PRK09276 154 -PDLDAIPEDV----AKKAKLMFINYPNNPTGAVADLEFFEEVVDFAKKYDIIVCHDAAYSEIAYDGYKPPSFLEVPGAK 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 236 ERTITIGSAGKTFSVTGWKLGWSIGPGHLIKHLRTVQQN---SVYTcatplqaALAEAfwiDIKRMDDPECYFNSLPKEL 312
Cdd:PRK09276 229 DVGIEFHSLSKTYNMTGWRIGFAVGNADLIAGLGKVKSNvdsGVFQ-------AIQEA---GIAALNGPQEVVEELRKIY 298
|
330 340 350
....*....|....*....|....*....|.
gi 1958752305 313 EVKRDRMACLLNSVGLKPIIPDGGYFIIADV 343
Cdd:PRK09276 299 QERRDILVEGLRKLGLEVEPPKATFYVWAPV 329
|
|
| ARO8 |
COG1167 |
DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain ... |
25-398 |
2.06e-30 |
|
DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain [Transcription, Amino acid transport and metabolism]; DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain is part of the Pathway/BioSystem: Lysine biosynthesis
Pssm-ID: 440781 [Multi-domain] Cd Length: 471 Bit Score: 121.86 E-value: 2.06e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 25 LAADSSVVNLGQGFPDITLPSY--VQEELSKAAFIDN--LNQYTRGFGHPSLVKALSCLYGK--IyqkQIDPnEEILVTV 98
Cdd:COG1167 102 LEAAPGVIDLGSGAPDPDLFPLaaLRRALRRALRRLPpaLLGYGDPQGLPELREAIARYLARrgV---PASP-DQILITS 177
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 99 GGYGSLFNAIQGLVDPGDEVIIMVPfydCYEPMV---KMAGAVPVFIPLRSkrtDGMkwtssdwtfNPQELESKFS-SKT 174
Cdd:COG1167 178 GAQQALDLALRALLRPGDTVAVESP---TYPGALaalRAAGLRLVPVPVDE---DGL---------DLDALEAALRrHRP 242
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 175 KAIILnTP--HNPIGKVYTREELQVIADLCIKHDTLCISDEVYEWLVYTGHKHIKIATLPGMwERTITIGSAGKTFSvTG 252
Cdd:COG1167 243 RAVYV-TPshQNPTGATMSLERRRALLELARRHGVPIIEDDYDSELRYDGRPPPPLAALDAP-GRVIYIGSFSKTLA-PG 319
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 253 WKLGWSIGPGHLIKHLRTVQQNSVYTCATPLQAALAEafWID-------IKRMddpecyfnslPKELEVKRDRMACLLNS 325
Cdd:COG1167 320 LRLGYLVAPGRLIERLARLKRATDLGTSPLTQLALAE--FLEsghydrhLRRL----------RREYRARRDLLLAALAR 387
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958752305 326 V---GLKPIIPDGGYFIIadvsslgVDLSDVKSDEpydyKFVKWMtKNKKLSAIPVSAFCDSESKPHFeklVRFCF 398
Cdd:COG1167 388 HlpdGLRVTGPPGGLHLW-------LELPEGVDAE----ALAAAA-LARGILVAPGSAFSADGPPRNG---LRLGF 448
|
|
| tyr_nico_aTase |
TIGR01265 |
tyrosine/nicotianamine family aminotransferase; This subfamily of pyridoxal ... |
22-381 |
8.77e-29 |
|
tyrosine/nicotianamine family aminotransferase; This subfamily of pyridoxal phosphate-dependent enzymes includes known examples of both tyrosine aminotransferase from animals and nicotianamine aminotransferase from barley.
Pssm-ID: 188123 Cd Length: 403 Bit Score: 116.29 E-value: 8.77e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 22 FTKLAADSSVVNLGQG----FPDITLPSYVQEELSKAAFIDNLNQYTRGFGHPSLVKALSCLYGKIYQKQIDPNEEILvT 97
Cdd:TIGR01265 24 KVKPNPEKPVIPLSHGdpsvFGNLRTDPEAEEAVKDALRSGKFNGYAPSVGALAAREAVAEYLSSDLPGKLTADDVVL-T 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 98 VGGYGSLFNAIQGLVDPGDEVIIMVPFYDCYEpmvkmagAVPVFIPLRSKRTDGMkwTSSDWTFNPQELESKFSSKTKAI 177
Cdd:TIGR01265 103 SGCSQAIEICIEALANPGANILVPRPGFPLYD-------TRAAFSGLEVRLYDLL--PEKDWEIDLDGLESLADEKTVAI 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 178 ILNTPHNPIGKVYTREELQVIADLCIKHDTLCISDEVYEWLVYTGHKHIKIATLPGMWERtITIGSAGKTFSVTGWKLGW 257
Cdd:TIGR01265 174 VVINPSNPCGSVFSRDHLQKIAEVAEKLGIPIIADEIYGHMVFGDAPFIPMASFASIVPV-LSLGGISKRWVVPGWRLGW 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 258 -------SIGPGHLIKHLRTVQQNSVYTCaTPLQAALAEAFwidikrMDDPECYFNSLPKELevKRDRMAC---LLNSVG 327
Cdd:TIGR01265 253 iiihdphGIFRDTVLQGLKNLLQRILGPA-TIVQGALPDIL------ENTPQEFFDGKISVL--KSNAELCyeeLKDIPG 323
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*..
gi 1958752305 328 LKPIIPDGGYFIIadvssLGVDLS---DVKSdepyDYKFVKWMTKNKKLSAIPVSAF 381
Cdd:TIGR01265 324 LVCPKPEGAMYLM-----VKLELElfpEIKD----DVDFCEKLAREESVICLPGSAF 371
|
|
| PTZ00433 |
PTZ00433 |
tyrosine aminotransferase; Provisional |
6-356 |
9.77e-28 |
|
tyrosine aminotransferase; Provisional
Pssm-ID: 185613 Cd Length: 412 Bit Score: 113.73 E-value: 9.77e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 6 KNAKRIEGLDQNVWVEFTKLAADSSVVNLGQGFP----DITLPSYVQEELSKAAFIDNLNQYTRGFGHPSLVKALSCLYG 81
Cdd:PTZ00433 10 KHAGRVFNPLRTVTDNAKPSPSPKSIIKLSVGDPtldgNLLTPAIQTKALVEAVDSQECNGYPPTVGSPEAREAVATYWR 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 82 KIY-----QKQIDPNEEILVTVGGYGSLFNAIQGLVDPGDEVIIMVPFYDCYEPMVKMAGAVPVFIPLRSkrtdgmkwtS 156
Cdd:PTZ00433 90 NSFvhkesLKSTIKKDNVVLCSGVSHAILMALTALCDEGDNILVPAPGFPHYETVCKAYGIEMRFYNCRP---------E 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 157 SDWTFNPQELESKFSSKTKAIILNTPHNPIGKVYTREELQVIADLCIKHDTLCISDEVYEWLVYTGHKHIKIATLPGMWE 236
Cdd:PTZ00433 161 KDWEADLDEIRRLVDDRTKALIMTNPSNPCGSNFSRKHVEDIIRLCEELRLPLISDEIYAGMVFNGATFTSVADFDTTVP 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 237 RTITIGSAgKTFSVTGWKLGWSI---GPGHLIKHLRTVQQNSVYTCA--TPLQAALAEAFwidikrMDDPECYFNSLPKE 311
Cdd:PTZ00433 241 RVILGGTA-KNLVVPGWRLGWLLlvdPHGNGGDFLDGMKRLGMLVCGpcSVVQAALGEAL------LNTPQEHLEQIVAK 313
|
330 340 350 360
....*....|....*....|....*....|....*....|....*....
gi 1958752305 312 LEVKRDRMACLL-NSVGLKPIIPDGGYFIiadvsSLGVDLS---DVKSD 356
Cdd:PTZ00433 314 LEEGAMVLYNHIgECIGLSPTMPRGSMFL-----MSRLDLEkfrDIKSD 357
|
|
| PRK06207 |
PRK06207 |
pyridoxal phosphate-dependent aminotransferase; |
88-411 |
5.82e-26 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 235742 Cd Length: 405 Bit Score: 108.31 E-value: 5.82e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 88 IDPNEEILVTVGGYGSLFNAIQGLVDPGDEVIIMVPFYDCYEPMVKMAGAVPVFIPLRSKRTDgmkwtsSDWTFNPQELE 167
Cdd:PRK06207 99 VDAADELIITPGTQGALFLAVAATVARGDKVAIVQPDYFANRKLVEFFEGEMVPVQLDYLSAD------KRAGLDLDQLE 172
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 168 SKFSSKTKAIILNTPHNPIGKVYTREELQVIADLCIKHDTLCISDEVYEWLVYTGHKHIKIATLPGMWERTITIGSAGKT 247
Cdd:PRK06207 173 EAFKAGVRVFLFSNPNNPAGVVYSAEEIAQIAALARRYGATVIVDQLYSRLLYDGTSYTHLRALPIDPENVITIMGPSKT 252
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 248 FSVTGWKLGWSIGPGHLIKHLRTVQQNSVYTCATPLQAALAEAFwidikrmDDPECYFNSLPKELEVKRDRMACLLNSV- 326
Cdd:PRK06207 253 ESLSGYRLGVAFGSPAIIDRMEKLQAIVSLRAAGYSQAVLRTWF-------SEPDGWMKDRIARHQAIRDDLLRVLRGVe 325
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 327 GLKPIIPDGGYFIIADVSSLGVDLSDvksdepydykFVKWMTKNKKLSAIPVSAFcdsesKPHFEKLVRFCFIK-KDSTL 405
Cdd:PRK06207 326 GVFVRAPQAGSYLFPRLPRLAVSLHD----------FVKILRLQAGVIVTPGTEF-----SPHTADSIRLNFSQdHAAAV 390
|
....*.
gi 1958752305 406 DAAEEI 411
Cdd:PRK06207 391 AAAERI 396
|
|
| tyr_amTase_E |
TIGR01264 |
tyrosine aminotransferase, eukaryotic; This model describes tyrosine aminotransferase as found ... |
61-411 |
6.16e-26 |
|
tyrosine aminotransferase, eukaryotic; This model describes tyrosine aminotransferase as found in animals and Trypanosoma cruzi. It is the first enzyme of a pathway of tyrosine degradation via homogentisate. Several plant enzyme designated as probable tyrosine aminotransferases are very closely related to an experimentally demonstrated nicotianamine aminotransferase, an enzyme in a siderophore (iron uptake chelator) biosynthesis pathway. These plant sequences are excluded from the model seed and score between the trusted an noise cutoffs. [Energy metabolism, Amino acids and amines]
Pssm-ID: 273529 [Multi-domain] Cd Length: 401 Bit Score: 108.33 E-value: 6.16e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 61 NQYTRGFGHPSLVKALSCLYGKIyQKQIDPNEEILvTVGGYGSLFNAIQGLVDPGDEVIIMVPFYDCYEPMVKMAGAVPV 140
Cdd:TIGR01264 67 NGYAPTVGALSAREAIASYYHNP-DGPIEADDVVL-CSGCSHAIEMCIAALANAGQNILVPRPGFPLYETLAESMGIEVK 144
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 141 FIPLRskrtdgmkwTSSDWTFNPQELESKFSSKTKAIILNTPHNPIGKVYTREELQVIADLCIKHDTLCISDEVYEWLVY 220
Cdd:TIGR01264 145 LYNLL---------PDKSWEIDLKQLESLIDEKTAALIVNNPSNPCGSVFSRQHLEEILAVAERQCLPIIADEIYGDMVF 215
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 221 TGHKHIKIATLPGMWERtITIGSAGKTFSVTGWKLGWSIGPGH------LIKHLRTVQQNSVYTCaTPLQAALAEAFwid 294
Cdd:TIGR01264 216 SGATFEPLASLSSTVPI-LSCGGLAKRWLVPGWRLGWIIIHDRrgilrdIRDGLVKLSQRILGPC-TIVQGALPSIL--- 290
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 295 ikrMDDPECYFNSLPKELEVKRDRMACLLNSV-GLKPIIPDGGYFIIadvssLGVDLSDVKSDEPyDYKFVKWMTKNKKL 373
Cdd:TIGR01264 291 ---LRTPQEYFDGTLSVLESNAMLCYGALAAVpGLRPVMPSGAMYMM-----VGIEMEHFPEFKN-DVEFTERLVAEQSV 361
|
330 340 350
....*....|....*....|....*....|....*...
gi 1958752305 374 SAIPVSAFcdseSKPHFEKLVRFCfiKKDSTLDAAEEI 411
Cdd:TIGR01264 362 FCLPGSCF----EYPGFFRVVLTV--PVVMMEEACSRI 393
|
|
| PRK08068 |
PRK08068 |
transaminase; Reviewed |
23-338 |
1.65e-25 |
|
transaminase; Reviewed
Pssm-ID: 181219 Cd Length: 389 Bit Score: 106.93 E-value: 1.65e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 23 TKLAADSSVVNLGQGFPDITLPSYVQEELSKAAFIDNLNQYTRGFGHPSLVKALSCLYGKIYQKQIDPNEEILVTVGGYG 102
Cdd:PRK08068 26 KKVAEGHDVINLGQGNPDQPTPEHIVEALQEAAENPANHKYSPFRGYPFLKEAAADFYKREYGVTLDPETEVAILFGGKA 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 103 SLFNAIQGLVDPGDEVIIMVPFYDCYEPMVKMAGAVPVFIPLRSKRtdgmkwtssDWTFNPQELESKFSSKTKAIILNTP 182
Cdd:PRK08068 106 GLVELPQCLMNPGDTILVPDPGYPDYLSGVALARAQFETMPLIAEN---------NFLPDYTKIPEEVAEKAKLMYLNYP 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 183 HNPIGKVYTREELQVIADLCIKHDTLCISDEVYEWLVYTGHKHIKIATLPGMWERTITIGSAGKTFSVTGWKLGWSIGPG 262
Cdd:PRK08068 177 NNPTGAVATKAFFEETVAFAKKHNIGVVHDFAYGAIGFDGQKPVSFLQTPGAKDVGIELYTLSKTFNMAGWRVAFAVGNE 256
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1958752305 263 HLIKHLRTVqQNSVYTCATP-LQAALAEAFwidikrMDDPECyFNSLPKELEVKRDRMACLLNSVGLKPIIPDGGYF 338
Cdd:PRK08068 257 SVIEAINLL-QDHLFVSLFGaIQDAAIEAL------LSDQSC-VAELVARYESRRNAFISACREIGWEVDAPKGSFF 325
|
|
| PRK09265 |
PRK09265 |
aminotransferase AlaT; Validated |
107-266 |
1.69e-25 |
|
aminotransferase AlaT; Validated
Pssm-ID: 181738 Cd Length: 404 Bit Score: 107.20 E-value: 1.69e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 107 AIQGLVDPGDEVIIMVPFYDCYEPMVKMAGAVPVFIplrskRTDgmkwTSSDWTFNPQELESKFSSKTKAIILNTPHNPI 186
Cdd:PRK09265 111 AMQALLNNGDEVLVPAPDYPLWTAAVSLSGGKPVHY-----LCD----EEAGWFPDLDDIRSKITPRTKAIVIINPNNPT 181
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 187 GKVYTREELQVIADLCIKHDTLCISDEVYEWLVYTGHKHIKIATL-PGMWerTITIGSAGKTFSVTGWKLGWSI--GPGH 263
Cdd:PRK09265 182 GAVYSKELLEEIVEIARQHNLIIFADEIYDKILYDGAVHISIASLaPDLL--CVTFNGLSKAYRVAGFRVGWMVlsGPKK 259
|
...
gi 1958752305 264 LIK 266
Cdd:PRK09265 260 HAK 262
|
|
| PRK09148 |
PRK09148 |
LL-diaminopimelate aminotransferase; |
10-290 |
3.58e-25 |
|
LL-diaminopimelate aminotransferase;
Pssm-ID: 181674 [Multi-domain] Cd Length: 405 Bit Score: 106.30 E-value: 3.58e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 10 RIEGLDQNVWVEFTKL-----AADSSVVNLGQGFPDITLPSYVQEELSKAAFIDNLNQYTRGFGHPSLVKALSCLYGKIY 84
Cdd:PRK09148 6 RIRRLPPYVFEQVNRLkaaarAAGADIIDLGMGNPDLPTPQHIVDKLCETAQDPRTHRYSASKGIPGLRRAQAAYYARRF 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 85 QKQIDPNEEILVTVGGYGSLFNAIQGLVDPGDEVIIMVPFYDCYEPMVKMAGAVPVFIPLrskrtdgmkwTSSDWTFNPQ 164
Cdd:PRK09148 86 GVKLNPDTQVVATLGSKEGFANMAQAITAPGDVILCPNPSYPIHAFGFIMAGGVIRSVPA----------EPDEEFFPAL 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 165 ELESKFS-SKTKAIILNTPHNPIGKVYTREELQVIADLCIKHDTLCISDEVYEWLVYTGHKHIKIATLPGMWERTITIGS 243
Cdd:PRK09148 156 ERAVRHSiPKPIALIVNYPSNPTAYVADLDFYKDVVAFAKKHDIIILSDLAYSEIYFDGNPPPSVLQVPGAKDVTVEFTS 235
|
250 260 270 280
....*....|....*....|....*....|....*....|....*..
gi 1958752305 244 AGKTFSVTGWKLGWSIGPGHLIKHLRTVQQNSVYTCATPLQAALAEA 290
Cdd:PRK09148 236 MSKTFSMAGWRMGFAVGNERLIAALTRVKSYLDYGAFTPIQVAATAA 282
|
|
| PRK07324 |
PRK07324 |
transaminase; Validated |
68-269 |
1.11e-24 |
|
transaminase; Validated
Pssm-ID: 235989 Cd Length: 373 Bit Score: 104.25 E-value: 1.11e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 68 GHPSLVKALSCLYgkiyqKQIDPnEEILVTVGGYGSLFNAIQGLVDPGDEVIIMVPFYDCYEPMVKMAGAVPVFIPLRSK 147
Cdd:PRK07324 63 GSPEFKEAVASLY-----QNVKP-ENILQTNGATGANFLVLYALVEPGDHVISVYPTYQQLYDIPESLGAEVDYWQLKEE 136
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 148 rtdgmkwtsSDWTFNPQELESKFSSKTKAIILNTPHNPIGKVYTREELQVIADLCIKHDTLCISDEVYEWLVYTGhkhiK 227
Cdd:PRK07324 137 ---------NGWLPDLDELRRLVRPNTKLICINNANNPTGALMDRAYLEEIVEIARSVDAYVLSDEVYRPLDEDG----S 203
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 1958752305 228 IATLPGMWERTITIGSAGKTFSVTGWKLGWSIGPGHLIKHLR 269
Cdd:PRK07324 204 TPSIADLYEKGISTNSMSKTYSLPGIRVGWIAANEEVIDILR 245
|
|
| PRK08175 |
PRK08175 |
aminotransferase; Validated |
31-400 |
5.56e-24 |
|
aminotransferase; Validated
Pssm-ID: 181268 [Multi-domain] Cd Length: 395 Bit Score: 102.48 E-value: 5.56e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 31 VVNLGQGFPDITLPSYVQEELSKAAFIDNLNQYTRGFGHPSLVKALSCLYGKIYQKQIDPNEEILVTVGGYGSLFNAIQG 110
Cdd:PRK08175 31 IIDFSMGNPDGPTPPHIVEKLCEVAQRPDTHGYSTSRGIPRLRRAISRWYQDRYDVDIDPESEAIVTIGSKEGLAHLMLA 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 111 LVDPGDEVIIMVPFYDCYEPMVKMAGAVPVFIPLrskrTDGMKWtssdwtFNPQELESKFS-SKTKAIILNTPHNPIGKV 189
Cdd:PRK08175 111 TLDHGDTVLVPNPSYPIHIYGAVIAGAQVRSVPL----VEGVDF------FNELERAIRESyPKPKMMILGFPSNPTAQC 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 190 YTREELQVIADLCIKHDTLCISDEVYEWLVYTGHKHIKIATLPGMWERTITIGSAGKTFSVTGWKLGWSIGPGHLIKHLR 269
Cdd:PRK08175 181 VELEFFEKVVALAKRYDVLVVHDLAYADIVYDGWKAPSIMQVPGAKDVAVEFFTLSKSYNMAGWRIGFMVGNPELVSALA 260
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 270 TVQQNSVYTCATPLQAAlaeafwiDIKRMDDPECYFNSLPKELEVKRDRMACLLNSVGLKPIIPDGGYFIIADVSslgvd 349
Cdd:PRK08175 261 RIKSYHDYGTFTPLQVA-------AIAALEGDQQCVRDIAEQYKRRRDVLVKGLHEAGWMVEMPKASMYVWAKIP----- 328
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*
gi 1958752305 350 lsdvksdEPY----DYKFVKWMTKNKKLSAIPVSAFCDseskpHFEKLVRFCFIK 400
Cdd:PRK08175 329 -------EPYaamgSLEFAKKLLNEAKVCVSPGIGFGD-----YGDTHVRFALIE 371
|
|
| HisC |
COG0079 |
Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase [Amino acid ... |
43-343 |
2.17e-23 |
|
Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase [Amino acid transport and metabolism]; Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis
Pssm-ID: 439849 [Multi-domain] Cd Length: 341 Bit Score: 100.21 E-value: 2.17e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 43 LPSYVQEELSKAAfiDNLNQYTRGfGHPSLVKALSCLYGkiyqkqIDPnEEILVTVGGYGSLFNAIQGLVDPGDEVIIMV 122
Cdd:COG0079 27 PPPKVLEAIAAAL--DALNRYPDP-DATALREALAEYYG------VPP-EQVLVGNGSDELIQLLARAFLGPGDEVLVPE 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 123 PFYDCYEPMVKMAGAVPVFIPLRSkrtdgmkwtssDWTFNPQELESKFSSKTKAIILNTPHNPIGKVYTREELQVIADLC 202
Cdd:COG0079 97 PTFSEYPIAARAAGAEVVEVPLDE-----------DFSLDLDALLAAITERTDLVFLCNPNNPTGTLLPREELEALLEAL 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 203 iKHDTLCISDEVY-EwlvYTGHKHiKIATLPGMWERTITIGSAGKTFSVTGWKLGWSIGPGHLIKHLRTVQQnsVYTCAT 281
Cdd:COG0079 166 -PADGLVVVDEAYaE---FVPEED-SALPLLARYPNLVVLRTFSKAYGLAGLRLGYAIASPELIAALRRVRG--PWNVNS 238
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1958752305 282 PLQAALAEAfwidikrMDDPEcYFNSLPKELEVKRDRMACLLNSVGLKPiIPDGGYFIIADV 343
Cdd:COG0079 239 LAQAAALAA-------LEDRA-YLEETRARLRAERERLAAALRALGLTV-YPSQANFVLVRV 291
|
|
| PRK07550 |
PRK07550 |
aminotransferase; |
26-338 |
2.37e-23 |
|
aminotransferase;
Pssm-ID: 181026 [Multi-domain] Cd Length: 386 Bit Score: 100.80 E-value: 2.37e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 26 AADSSVVNLGQGFPDITLPSYVQEELSKAAFIDNLNQYTRGFGHPSLVKALSCLYGKIYQKQIDPnEEILVTVGGYGSLF 105
Cdd:PRK07550 26 GADGPLIDLSQAVPGYPPPPELLRALAEAAADPAAHLYGPVEGLPELREAYAAHYSRLYGAAISP-EQVHITSGCNQAFW 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 106 NAIQGLVDPGDEVIIMVPFYDCYEPMVKMAGAVPVFIPLRSKRtDGMKwtssdwtfNPQELESKFSSKTKAIILNTPHNP 185
Cdd:PRK07550 105 AAMVTLAGAGDEVILPLPWYFNHKMWLDMLGIRPVYLPCDEGP-GLLP--------DPAAAEALITPRTRAIALVTPNNP 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 186 IGKVYTREELQVIADLCIKHDTLCISDEVY-EWLVYTGHKHIKIATlPGmWERT-ITIGSAGKTFSVTGWKLGWSIGPGH 263
Cdd:PRK07550 176 TGVVYPPELLHELYDLARRHGIALILDETYrDFDSGGGAPHDLFAD-PD-WDDTlVHLYSFSKSYALTGHRVGAVVASPA 253
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 264 LIKHLRTVQQNsVYTCATPL-QAALAEAF-----WIDIKRMddpecyfnslpkELEVKRDRMACLLNSVGLKPIIPDGGY 337
Cdd:PRK07550 254 RIAEIEKFMDT-VAICAPRIgQIAVAWGLpnladWRAGNRA------------EIARRRDAFRAVFARLPGWELLASGAY 320
|
.
gi 1958752305 338 F 338
Cdd:PRK07550 321 F 321
|
|
| PRK13355 |
PRK13355 |
bifunctional HTH-domain containing protein/aminotransferase; Provisional |
100-259 |
1.82e-22 |
|
bifunctional HTH-domain containing protein/aminotransferase; Provisional
Pssm-ID: 237361 [Multi-domain] Cd Length: 517 Bit Score: 99.43 E-value: 1.82e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 100 GYGSLFN-AIQGLVDPGDEVIIMVPFYDCYEPMVKMAGAVPVFIplrskRTDgmkwTSSDWTFNPQELESKFSSKTKAII 178
Cdd:PRK13355 216 GVSELINlSMSALLDDGDEVLIPSPDYPLWTACVNLAGGTAVHY-----RCD----EQSEWYPDIDDIRSKITSRTKAIV 286
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 179 LNTPHNPIGKVYTREELQVIADLCIKHDTLCISDEVYEWLVYTGHKHIKIATL-PGMWerTITIGSAGKTFSVTGWKLGW 257
Cdd:PRK13355 287 IINPNNPTGALYPREVLQQIVDIAREHQLIIFSDEIYDRLVMDGLEHTSIASLaPDLF--CVTFSGLSKSHMIAGYRIGW 364
|
..
gi 1958752305 258 SI 259
Cdd:PRK13355 365 MI 366
|
|
| PRK05942 |
PRK05942 |
aspartate aminotransferase; Provisional |
8-317 |
5.10e-22 |
|
aspartate aminotransferase; Provisional
Pssm-ID: 180317 Cd Length: 394 Bit Score: 97.10 E-value: 5.10e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 8 AKRIEGLDQNVWVEFTKLAADS-----SVVNLGQGFPDITLPSYVQEElSKAAFIDNLNQYTRGF-GHPSLVKALSCLYG 81
Cdd:PRK05942 9 ADRLQALPPYVFARLDELKARAreqglDLIDLGMGNPDGAAPQPVIEA-AIAALADPQNHGYPPFeGTASFRQAITDWYH 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 82 KIYQKQIDPNEEILVTVGGYGSLFNAIQGLVDPGDEVIIMVPFYDCY--EPMVkmAGAVPVFIPLRSKRtdgmkwtssDW 159
Cdd:PRK05942 88 RRYGVELDPDSEALPLLGSKEGLTHLALAYVNPGDVVLVPSPAYPAHfrGPLI--AGAQIYPIILKPEN---------DW 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 160 TFNPQELESKFSSKTKAIILNTPHNPIGKVYTREELQVIADLCIKHDTLCISDEVYEWLVYTGHKHIKIATLPGMWERTI 239
Cdd:PRK05942 157 LIDLSSIPEEVAQQAKILYFNYPSNPTTATAPREFFEEIVAFARKYEIMLVHDLCYAELAFDGYQPTSLLEIPGAKDIGV 236
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1958752305 240 TIGSAGKTFSVTGWKLGWSIGPGHLIKHLRTVQQNSVYTCATPLQAALAEAFWIdikrmddPECYFNSLPKELEVKRD 317
Cdd:PRK05942 237 EFHTLSKTYNMAGWRVGFVVGNRHIIQGLRTLKTNLDYGIFSALQKAAETALQL-------PDSYLQQVQERYRTRRD 307
|
|
| PRK06290 |
PRK06290 |
LL-diaminopimelate aminotransferase; |
28-377 |
1.61e-20 |
|
LL-diaminopimelate aminotransferase;
Pssm-ID: 235772 Cd Length: 410 Bit Score: 92.79 E-value: 1.61e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 28 DSSVVNLGQGFPDITLPSYVQEELSK-AAFIDNlnqytRGF---GHPSLVKALSCLYGKIYQ-KQIDPNEEILVTVGGYG 102
Cdd:PRK06290 43 DMELIDMGVGEPDEMADESVVEVLCEeAKKPEN-----RGYadnGIQEFKEAAARYMEKVFGvKDIDPVTEVIHSIGSKP 117
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 103 SLFNAIQGLVDPGDEVIIMVPFYDCYEPMVKMAGAVPVFIPLRSKRTdgmkwtssdwtFNPqELES---KFSSKTKAIIL 179
Cdd:PRK06290 118 ALAMLPSCFINPGDVTLMTVPGYPVTGTHTKYYGGEVYNLPLLEENN-----------FLP-DLDSipkDIKEKAKLLYL 185
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 180 NTPHNPIGKVYTREELQVIADLCIKHDTLCISDEVYEWLVYTGhKHIKIATLPGMWERTITIGSAGKTFSVTGWKLGWSI 259
Cdd:PRK06290 186 NYPNNPTGAVATKEFYEEVVDFAKENNIIVVQDAAYAALTFDG-KPLSFLSVPGAKEVGVEIHSLSKAYNMTGWRLAFVV 264
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 260 GPGHLIKHLRTVQQNSVYTCATPLQAALAEAfwidikrMDDPEcyfnsLPKELEVKRDR----MACLLNSVGLKPIIPDG 335
Cdd:PRK06290 265 GNELIVKAFATVKDNNDSGQFIAIQKAGIYA-------LDHPE-----ITEKIREKYSRrldkLVKILNEVGFKAEMPGG 332
|
330 340 350 360
....*....|....*....|....*....|....*....|..
gi 1958752305 336 GYFIIADVSSLGVDLSDVKSDEpydyKFVKWMTKNKKLSAIP 377
Cdd:PRK06290 333 TFYLYVKAPKGTKSGIKFENAE----EFSQYLIKEKLISTVP 370
|
|
| PRK06225 |
PRK06225 |
pyridoxal phosphate-dependent aminotransferase; |
21-353 |
1.49e-18 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 235749 [Multi-domain] Cd Length: 380 Bit Score: 86.73 E-value: 1.49e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 21 EFTKLAADSSVVNLGQGFPDITLPSYVQEELSKAAFIDNLNQYTRGFGHPSLVKALSCLYGKiyqkqidPNEEILVTVGG 100
Cdd:PRK06225 20 FFDYVFKDKEMIWMGQNTNHLGPHEEVREAMIRCIEEGEYCKYPPPEGFPELRELILKDLGL-------DDDEALITAGA 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 101 YGSLFNAIQGLVDPGDEVIIMVPFYDCYEPMVKMAGAVPVFIPLRSKrtdgmkwtSSDWTFNPQELESKFSSKTKAIILN 180
Cdd:PRK06225 93 TESLYLVMRAFLSPGDNAVTPDPGYLIIDNFASRFGAEVIEVPIYSE--------ECNYKLTPELVKENMDENTRLIYLI 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 181 TPHNPIGKVYTREELQVIADLCIKHDTLCISDEVYEWLVYTGHKHIKIATlpgmwERTITIGSAGKTFSVTGWKLGWSIG 260
Cdd:PRK06225 165 DPLNPLGSSYTEEEIKEFAEIARDNDAFLLHDCTYRDFAREHTLAAEYAP-----EHTVTSYSFSKIFGMAGLRIGAVVA 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 261 PGHLIKHLRTVQQNSVYTCATPLQAALA----EAFWID-IKRmddpECYFNslpKELeVKRDRMACllnsVGLK-PIIPD 334
Cdd:PRK06225 240 TPDLIEVVKSIVINDLGTNVIAQEAAIAglkvKDEWIDrIRR----TTFKN---QKL-IKEAVDEI----EGVFlPVYPS 307
|
330
....*....|....*....
gi 1958752305 335 GGYFIIADVSSLGVDLSDV 353
Cdd:PRK06225 308 HGNMMVIDISEAGIDPEDL 326
|
|
| PRK08636 |
PRK08636 |
LL-diaminopimelate aminotransferase; |
10-325 |
6.02e-15 |
|
LL-diaminopimelate aminotransferase;
Pssm-ID: 236316 Cd Length: 403 Bit Score: 75.90 E-value: 6.02e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 10 RIEGLDQNVWVEFT--KLA---ADSSVVNLGQGFPDITLPSYVQEELSKAAFIDNLNQYTRGFGHPSLVKALSCLYGKIY 84
Cdd:PRK08636 9 KIKRLPKYVFAEVNelKMAarrAGEDIIDFSMGNPDGPTPQHIIDKLCESAQKPKTHGYSVSKGIYKLRLAICNWYKRKY 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 85 QKQIDPNEEILVTVG---GYGSLFNAIqglVDPGDEVIIMVPFYDCYEPMVKMAGAVPVFIPLrsKRTDGMKWTSSDWTF 161
Cdd:PRK08636 89 NVDLDPETEVVATMGskeGYVHLVQAI---TNPGDVAIVPDPAYPIHSQAFILAGGNVHKMPL--EYNEDFELDEDQFFE 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 162 NPQELESKFSSKTKAIILNTPHNPIGKVYTREELQVIADLCIKHDTLCISDEVYEWLVYTGHKHIKIATLPGMWERTITI 241
Cdd:PRK08636 164 NLEKALRESSPKPKYVVVNFPHNPTTATVEKSFYERLVALAKKERFYIISDIAYADITFDGYKTPSILEVEGAKDVAVES 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 242 GSAGKTFSVTGWKLGWSIGPGHLIKHLRTVQQNSVYTCATPLQAALAEAFwidikrMDDPECYfnslpKEL-EVKRDRMA 320
Cdd:PRK08636 244 YTLSKSYNMAGWRVGFVVGNKKLVGALKKIKSWLDYGMFTPIQVAATIAL------DGDQSCV-----EEIrETYRKRRD 312
|
....*
gi 1958752305 321 CLLNS 325
Cdd:PRK08636 313 VLIES 317
|
|
| PRK05839 |
PRK05839 |
succinyldiaminopimelate transaminase; |
34-317 |
7.23e-15 |
|
succinyldiaminopimelate transaminase;
Pssm-ID: 180281 Cd Length: 374 Bit Score: 75.49 E-value: 7.23e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 34 LGQGFPDITLPSYVQEEL-SKAAFidnLNQYTRGFGHPSLVKALSCLYGKIYQKQIDPNEeILVTVGGYGSLFNAIQ-GL 111
Cdd:PRK05839 29 LTIGEPQFETPKFIQDALkNNAHL---LNKYPKSAGEESLREAQRGFFKRRFKIELKENE-LIPTFGTREVLFNFPQfVL 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 112 VDPGDEVIIMV-PFYDCYEPMVKMAGAVPVFIPLrSKRTDgmkwtssdwtFNPqELESKFSSKTKAIILNTPHNPIGKVY 190
Cdd:PRK05839 105 FDKQNPTIAYPnPFYQIYEGAAIASRAKVLLMPL-TKEND----------FTP-SLNEKELQEVDLVILNSPNNPTGRTL 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 191 TREELQVIADLCIKHDTLCISDEVYEWLvYTGHKhikiatLPGMWERTITIG-----------SAGKTFSVTGWKLGWSI 259
Cdd:PRK05839 173 SLEELIEWVKLALKHDFILINDECYSEI-YENTP------PPSLLEASILVGnesfknvlvinSISKRSSAPGLRSGFIA 245
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*...
gi 1958752305 260 GPGHLIKHLRTVQQNSVYTCATPLQAAlAEAFWIDikrMDDPECYFNSLPKELEVKRD 317
Cdd:PRK05839 246 GDASILKKYKAYRTYLGCASPLPLQKA-AAVAWLD---DEHAEFFRNIYAKNLKLARE 299
|
|
| PRK07366 |
PRK07366 |
LL-diaminopimelate aminotransferase; |
8-272 |
7.36e-15 |
|
LL-diaminopimelate aminotransferase;
Pssm-ID: 180947 Cd Length: 388 Bit Score: 75.49 E-value: 7.36e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 8 AKRIEGLDQNVWVEFTK-----LAADSSVVNLGQGFPDITLPSYVQEELSKAAFIDNLNQYTRGFGHPSLVKALSCLYGK 82
Cdd:PRK07366 4 AQRLQPLQSNVFADMDRakaqaRAAGKELIDLSLGSSDLPAPAHALEAIAQSLHDPSTHGYLLFHGTLDFREAAAQWYEQ 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 83 IYQKQIDPNEEILVTVG---GYGSLFNAIqglVDPGDEVIIMVPFYDCYEPMVKMAGAVPVFIPLRSKRTdgmkwtssdw 159
Cdd:PRK07366 84 RFGLAVDPETEVLPLIGsqeGTAHLPLAV---LNPGDFALLLDPGYPSHAGGVYLAGGQIYPMPLRAEND---------- 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 160 tFNPQ--ELESKFSSKTKAIILNTPHNPIGKVYTREELQVIADLCIKHDTLCISDEVYEWLVYTGhkhikIATLPGMW-- 235
Cdd:PRK07366 151 -FLPVfaDIPTEVLAQARLMVLSYPHNPTTAIAPLSFFQEAVAFCQQHDLVLVHDFPYVDLVFDG-----EVEPPSILqa 224
|
250 260 270 280
....*....|....*....|....*....|....*....|.
gi 1958752305 236 --ERTITIG--SAGKTFSVTGWKLGWSIGPGHLIKHLRTVQ 272
Cdd:PRK07366 225 dpEKSVSIEffTLSKSYNMGGFRIGFAIGNAQLIQALRQVK 265
|
|
| PLN00145 |
PLN00145 |
tyrosine/nicotianamine aminotransferase; Provisional |
31-257 |
5.24e-14 |
|
tyrosine/nicotianamine aminotransferase; Provisional
Pssm-ID: 215074 [Multi-domain] Cd Length: 430 Bit Score: 73.27 E-value: 5.24e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 31 VVNLGQG----FPDITLPSYVQEELSKAAFIDNLNQYTRGFGHPSLVKALSCLYGKIYQKQIDPNEeILVTVGGYGSLFN 106
Cdd:PLN00145 54 VLPLGHGdpsaFPCFRTAPEAEDAVAAALRSGKYNSYSTCVGLLPARRAIAEYLSRDLPYELSTDD-IYLTAGCAQAIEI 132
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 107 AIQGLVDPGDEVIIMVPFYDCYEpmvkmagAVPVFIPLRSKRTDGMKwtSSDWTFNPQELESKFSSKTKAIILNTPHNPI 186
Cdd:PLN00145 133 IMSVLAQPGANILLPRPGYPLYE-------ARAVFSGLEVRHFDLLP--ERGWEVDLEGVEALADENTVAMVIINPNNPC 203
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1958752305 187 GKVYTREELQVIADLCIKHDTLCISDEVYEWLVYTGHKHIKIATLpGMWERTITIGSAGKTFSVTGWKLGW 257
Cdd:PLN00145 204 GSVYSYEHLAKIAETARKLGILVIADEVYDHLTFGSKPFVPMGVF-GEVAPVLTLGSISKRWVVPGWRLGW 273
|
|
| PLN02656 |
PLN02656 |
tyrosine transaminase |
27-287 |
2.52e-13 |
|
tyrosine transaminase
Pssm-ID: 178262 [Multi-domain] Cd Length: 409 Bit Score: 71.11 E-value: 2.52e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 27 ADSSVVNLGQGFPDI-----TLPsYVQEELSKAAFIDNLNQYTRGFGHPSLVKALSCLYGKIYQKQIDpNEEILVTVGGY 101
Cdd:PLN02656 29 NGKRVISLGMGDPTAyscfhTTH-VAQEAVVDALQSNKFNGYAPTVGLPQARRAIAEYLSRDLPYKLS-LDDVFITSGCT 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 102 GSLFNAIQGLVDPGDEVIIMVPFYDCYEPMVKMAGAVPVFIPLRSKRtdgmkwtssDWTFNPQELESKFSSKTKAIILNT 181
Cdd:PLN02656 107 QAIDVALSMLARPGANILLPRPGFPIYELCAAFRHLEVRYVDLLPEK---------GWEVDLDAVEALADQNTVALVIIN 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 182 PHNPIGKVYTREELQVIADLCIKHDTLCISDEVYEWLVYTGHKHIKIATLpGMWERTITIGSAGKTFSVTGWKLGWSI-- 259
Cdd:PLN02656 178 PGNPCGNVYSYQHLKKIAETAEKLKILVIADEVYGHLAFGSNPFVPMGVF-GSIVPVLTLGSLSKRWIVPGWRLGWFVtt 256
|
250 260 270
....*....|....*....|....*....|...
gi 1958752305 260 GPGHLIKHLRTVQQNSVY-----TCATPLQAAL 287
Cdd:PLN02656 257 DPSGSFRDPKIVERIKKYfdilgGPATFIQAAV 289
|
|
| PLN00143 |
PLN00143 |
tyrosine/nicotianamine aminotransferase; Provisional |
87-377 |
1.29e-12 |
|
tyrosine/nicotianamine aminotransferase; Provisional
Pssm-ID: 165711 [Multi-domain] Cd Length: 409 Bit Score: 68.89 E-value: 1.29e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 87 QIDPnEEILVTVGGYGSLFNAIQGLVDPGDEVIIMVPFYDCYEpmvkmagAVPVFIPLRSKRTDGMKwtSSDWTFNPQEL 166
Cdd:PLN00143 94 QLSP-DDVYLTLGCKHAAEIIIKVLARPEANILLPRPGFPDVE-------TYAIFHHLEIRHFDLLP--EKGWEVDLDAV 163
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 167 ESKFSSKTKAIILNTPHNPIGKVYTREELQVIADLCIKHDTLCISDEVYEWLVYtGHKHIKIATLPGMWERTITIGSAGK 246
Cdd:PLN00143 164 EAIADENTIAMVIINPGNPCGSVYSYEHLNKIAETARKLGILVIADEVYGHIVF-GSKPFVPMGLFASIVPVITLGSISK 242
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 247 TFSVTGWKLGWSI--GPGHLIKHLRTVQQNSVYTCATPLQAALAEAFWIDIKRMDDPECY---FNSLPKELEVKRDRMA- 320
Cdd:PLN00143 243 RWMIPGWGLGWLVtcDPSGLLQICEIADSIKKALNPAPFPPTFIQAAIPEILEKTTEDFFsktINILRAALAFCYDKLKe 322
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 321 --CLlnsvgLKPIIPDGGYFIIADVS-SLGVDLSDvksdepyDYKFVKWMTKNKKLSAIP 377
Cdd:PLN00143 323 ipCI-----MCPQKAEGAFFALVKLNlLLLEDIED-------DMEFCLKLAKEESLIILP 370
|
|
| PLN02187 |
PLN02187 |
rooty/superroot1 |
28-287 |
6.59e-12 |
|
rooty/superroot1
Pssm-ID: 215119 [Multi-domain] Cd Length: 462 Bit Score: 67.06 E-value: 6.59e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 28 DSSVVNLGQGFPDItLPSYVQEELSKAAFIDNL-----NQYTRGFGHPSLVKALSCLYGKIYQKQIDPnEEILVTVGGYG 102
Cdd:PLN02187 65 NKTILPLGHGDPSV-YPCFRTCIEAEDAVVDVLrsgkgNSYGPGAGILPARRAVADYMNRDLPHKLTP-EDIFLTAGCNQ 142
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 103 SLFNAIQGLVDPGDEVIIMVPFYDCYEPMVKMAGavpvfipLRSKRTDGMKwtSSDWTFNPQELESKFSSKTKAIILNTP 182
Cdd:PLN02187 143 GIEIVFESLARPNANILLPRPGFPHYDARAAYSG-------LEVRKFDLLP--EKEWEIDLEGIEAIADENTVAMVVINP 213
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 183 HNPIGKVYTREELQVIADLCIKHDTLCISDEVYEWLVYTGHKHIKIATLPGMWErTITIGSAGKTFSVTGWKLGWSI--- 259
Cdd:PLN02187 214 NNPCGNVYSHDHLKKVAETARKLGIMVISDEVYDRTIFGDNPFVSMGKFASIVP-VLTLAGISKGWVVPGWKIGWIAlnd 292
|
250 260 270
....*....|....*....|....*....|..
gi 1958752305 260 --GPGHLIKHLRTVQQNSVYT--CATPLQAAL 287
Cdd:PLN02187 293 peGVFETTKVLQSIKQNLDVTpdPATIIQAAL 324
|
|
| PRK09147 |
PRK09147 |
succinyldiaminopimelate transaminase; Provisional |
22-215 |
7.06e-12 |
|
succinyldiaminopimelate transaminase; Provisional
Pssm-ID: 236393 Cd Length: 396 Bit Score: 66.44 E-value: 7.06e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 22 FTKLA---------ADSSVVNLGQGFPDITLPSYVQEELskAAFIDNLNQYTRGFGHPSLVKALSCLYGKIYQKQ-IDPN 91
Cdd:PRK09147 13 FEKLRalfagvtppADLPPISLSIGEPKHPTPAFIKDAL--AANLDGLASYPTTAGLPALREAIAAWLERRYGLPaLDPA 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 92 EEILVTVGGYGSLFNAIQGLVDPGDEVIIMV---PFYDCYEPMVKMAGAVPVFIPLRSKRTDGMkwtssDWTFNPQELes 168
Cdd:PRK09147 91 TQVLPVNGSREALFAFAQTVIDRDGPGPLVVcpnPFYQIYEGAALLAGAEPYFLNCDPANNFAP-----DFDAVPAEV-- 163
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 1958752305 169 kfSSKTKAIILNTPHNPIGKVYTREELQVIADLCIKHDTLCISDEVY 215
Cdd:PRK09147 164 --WARTQLLFVCSPGNPTGAVLPLDDWKKLFALSDRYGFVIASDECY 208
|
|
| PLN02607 |
PLN02607 |
1-aminocyclopropane-1-carboxylate synthase |
68-256 |
2.45e-10 |
|
1-aminocyclopropane-1-carboxylate synthase
Pssm-ID: 215327 [Multi-domain] Cd Length: 447 Bit Score: 61.83 E-value: 2.45e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 68 GHPSLVKALSCLYGKIY--QKQIDPnEEILVTVGGYGS--LFNAIqgLVDPGDEVIIMVPFYDCYEPMVKMAGAVPVfIP 143
Cdd:PLN02607 96 GLKSFRQAMASFMEQIRggKARFDP-DRIVLTAGATAAneLLTFI--LADPGDALLVPTPYYPGFDRDLRWRTGVKI-VP 171
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 144 LRSKRTDGMKWTssdwtfnPQELESKFSS------KTKAIILNTPHNPIGKVYTREELQVIADLCIKHDTLCISDEVYEW 217
Cdd:PLN02607 172 IHCDSSNNFQVT-------PQALEAAYQEaeaaniRVRGVLITNPSNPLGATVQRSVLEDILDFVVRKNIHLVSDEIYSG 244
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 1958752305 218 LVYTGHKHIKIATL------PGMWERTITIGSAGKTFSVTGWKLG 256
Cdd:PLN02607 245 SVFSASEFVSVAEIveargyKGVAERVHIVYSLSKDLGLPGFRVG 289
|
|
| PTZ00377 |
PTZ00377 |
alanine aminotransferase; Provisional |
63-224 |
3.56e-10 |
|
alanine aminotransferase; Provisional
Pssm-ID: 240391 [Multi-domain] Cd Length: 481 Bit Score: 61.52 E-value: 3.56e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 63 YTRGFGHPSLVKALSCLYGKIYQKQIDPNEeILVTVGGYGSLFNAIQGLV-DPGDEVIIMVPFYDCYEPMVKMAGAVPVF 141
Cdd:PTZ00377 111 YTDSAGYPFVRKAVAAFIERRDGVPKDPSD-IFLTDGASSGIKLLLQLLIgDPSDGVMIPIPQYPLYSAAITLLGGKQVP 189
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 142 IPLRSkrtdgmkwtSSDWTFNPQELESKFS------SKTKAIILNTPHNPIGKVYTREELQVIADLCIKHDTLCISDEVY 215
Cdd:PTZ00377 190 YYLDE---------EKGWSLDQEELEEAYEqavrngITPRALVVINPGNPTGQVLTRDVMEEIIKFCYEKGIVLMADEVY 260
|
....*....
gi 1958752305 216 EWLVYTGHK 224
Cdd:PTZ00377 261 QENIYDGEK 269
|
|
| PRK06855 |
PRK06855 |
pyridoxal phosphate-dependent aminotransferase; |
158-257 |
1.18e-09 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 180734 Cd Length: 433 Bit Score: 59.96 E-value: 1.18e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 158 DWTFNPQELES--KFSSKTKAIILNTPHNPIGKVYTREELQVIADLCIKHDTLCISDEVYEWLVYTGHKHIKIATL---- 231
Cdd:PRK06855 154 NWYPDLDDLENkvKYNPSIAGILLINPDNPTGAVYPKEILREIVDIAREYDLFIICDEIYNNIVYNGKKTVPLSEVigdv 233
|
90 100
....*....|....*....|....*.
gi 1958752305 232 PGMWERTITigsagKTFSVTGWKLGW 257
Cdd:PRK06855 234 PGIALKGIS-----KELPWPGSRCGW 254
|
|
| PLN02376 |
PLN02376 |
1-aminocyclopropane-1-carboxylate synthase |
89-229 |
1.58e-09 |
|
1-aminocyclopropane-1-carboxylate synthase
Pssm-ID: 178004 [Multi-domain] Cd Length: 496 Bit Score: 59.71 E-value: 1.58e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 89 DPnEEILVTVGGYGSLFNAIQGLVDPGDEVIIMVPFYDCYEPMVKMAGAVPVfIPLRSKRTDGMKWT--SSDWTFNPQEL 166
Cdd:PLN02376 118 DP-ERVVMSGGATGANETIMFCLADPGDVFLIPSPYYAAFDRDLRWRTGVEI-IPVPCSSSDNFKLTvdAADWAYKKAQE 195
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1958752305 167 ESKfssKTKAIILNTPHNPIGKVYTREELQVIADLCIKHDTLCISDEVYEWLVYTGHKHIKIA 229
Cdd:PLN02376 196 SNK---KVKGLILTNPSNPLGTMLDKDTLTNLVRFVTRKNIHLVVDEIYAATVFAGGDFVSVA 255
|
|
| PRK03321 |
PRK03321 |
putative aminotransferase; Provisional |
43-215 |
3.41e-09 |
|
putative aminotransferase; Provisional
Pssm-ID: 179559 Cd Length: 352 Bit Score: 58.05 E-value: 3.41e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 43 LPSyVQEELSKAAfiDNLNQYTrGFGHPSLVKALSCLYGkiyqkqIDPnEEILVTVGGYGSLFNAIQGLVDPGDEVIIMV 122
Cdd:PRK03321 37 LPS-VRAAIARAA--AGVNRYP-DMGAVELRAALAEHLG------VPP-EHVAVGCGSVALCQQLVQATAGPGDEVIFAW 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 123 PFYDCYEPMVKMAGAVPVFIPLRSKRT---DGMKWTSSDwtfnpqeleskfssKTKAIILNTPHNPIGKVYTREELQVIA 199
Cdd:PRK03321 106 RSFEAYPILVQVAGATPVQVPLTPDHThdlDAMAAAITD--------------RTRLIFVCNPNNPTGTVVTPAELARFL 171
|
170
....*....|....*.
gi 1958752305 200 DlCIKHDTLCISDEVY 215
Cdd:PRK03321 172 D-AVPADVLVVLDEAY 186
|
|
| PLN03026 |
PLN03026 |
histidinol-phosphate aminotransferase; Provisional |
90-356 |
6.24e-09 |
|
histidinol-phosphate aminotransferase; Provisional
Pssm-ID: 178597 Cd Length: 380 Bit Score: 57.40 E-value: 6.24e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 90 PNEEILVTVGGyGSLFNAIQGLV-DPGDEVIIMVPFYDCYEPMVKMAGAVPVFIPlrskRTDGMKWTSsdwtfnPQELES 168
Cdd:PLN03026 102 ESENILVGCGA-DELIDLLMRCVlDPGDKIIDCPPTFGMYVFDAAVNGAEVIKVP----RTPDFSLDV------PRIVEA 170
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 169 KFSSKTKAIILNTPHNPIGKVYTREELQVIADLCIkhdtLCISDEVYewlvytghkhIKIATLPGM------WERTITIG 242
Cdd:PLN03026 171 VETHKPKLLFLTSPNNPDGSIISDDDLLKILELPI----LVVLDEAY----------IEFSTQESRmkwvkkYDNLIVLR 236
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 243 SAGKTFSVTGWKLGWSIGPGHLIKHLRTVQQNSVYTCATPLQAALAeafwidikrMDDPEcYFNSLPKELEVKRDRMACL 322
Cdd:PLN03026 237 TFSKRAGLAGLRVGYGAFPLSIIEYLWRAKQPYNVSVAAEVAACAA---------LSNPK-YLEDVKNALVEERERLFGL 306
|
250 260 270
....*....|....*....|....*....|....*
gi 1958752305 323 LNSVG-LKPiIPDGGYFIIADVSSlGVDLSDVKSD 356
Cdd:PLN03026 307 LKEVPfLEP-YPSDANFILCRVTS-GRDAKKLKED 339
|
|
| PLN02450 |
PLN02450 |
1-aminocyclopropane-1-carboxylate synthase |
68-228 |
7.46e-08 |
|
1-aminocyclopropane-1-carboxylate synthase
Pssm-ID: 178069 [Multi-domain] Cd Length: 468 Bit Score: 54.37 E-value: 7.46e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 68 GHPSLVKALSCLYGKI--YQKQIDPNEeILVTVGGYGSLFNAIQGLVDPGDEVIIMVPFYDCYEPMVKMAGAVPVfIPLR 145
Cdd:PLN02450 87 GLPAFKNALAEFMSEIrgNKVTFDPNK-LVLTAGATSANETLMFCLAEPGDAFLLPTPYYPGFDRDLKWRTGVEI-VPIH 164
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 146 SKRTDGMKWTSSDWTFNPQELEsKFSSKTKAIILNTPHNPIGKVYTREELQVIADLCIKHDTLCISDEVYEWLVYTGHKH 225
Cdd:PLN02450 165 CSSSNGFQITESALEEAYQQAQ-KLNLKVKGVLITNPSNPLGTTTTRTELNLLVDFITAKNIHLISDEIYSGTVFDSPGF 243
|
...
gi 1958752305 226 IKI 228
Cdd:PLN02450 244 VSV 246
|
|
| AAT_I |
cd01494 |
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP) ... |
91-215 |
5.61e-06 |
|
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. Structure and sequence analysis has revealed that the PLP dependent enzymes can be classified into four major groups of different evolutionary origin: aspartate aminotransferase superfamily (fold type I), tryptophan synthase beta superfamily (fold type II), alanine racemase superfamily (fold type III), and D-amino acid superfamily (fold type IV) and Glycogen phophorylase family (fold type V).
Pssm-ID: 99742 [Multi-domain] Cd Length: 170 Bit Score: 46.22 E-value: 5.61e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 91 NEEILVTVGGYGSLFNAIQGLVDPGDEVII-MVPFYDCYEPMVKMAGAVPVFIPlrSKRTDGMKWtssdwtfNPQELE-S 168
Cdd:cd01494 17 NDKAVFVPSGTGANEAALLALLGPGDEVIVdANGHGSRYWVAAELAGAKPVPVP--VDDAGYGGL-------DVAILEeL 87
|
90 100 110 120
....*....|....*....|....*....|....*....|....*..
gi 1958752305 169 KFSSKTKAIILNTPHNPIGKVYTREElqvIADLCIKHDTLCISDEVY 215
Cdd:cd01494 88 KAKPNVALIVITPNTTSGGVLVPLKE---IRKIAKEYGILLLVDAAS 131
|
|
| PRK05166 |
PRK05166 |
histidinol-phosphate transaminase; |
90-343 |
1.36e-05 |
|
histidinol-phosphate transaminase;
Pssm-ID: 179950 Cd Length: 371 Bit Score: 47.05 E-value: 1.36e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 90 PNEEILVtvgGYGS--LFNAI-QGLVDPGDEVIIMVPFYDCYEPMVKMAGAvpvfiplRSKRTDgmkwTSSDWTFNPQEL 166
Cdd:PRK05166 87 PADRIIL---GNGSedLIAVIcRAVLRPGDRVVTLYPSFPLHEDYPTMMGA-------RVERVT----VTPDLGFDLDAL 152
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 167 ESKFSSKTKAIILNTPHNPIGKVYTREELQVIADLCiKHDTLCISDEVYeWLVYTGHKHIKIAT------LPGMWERTIT 240
Cdd:PRK05166 153 CAAVARAPRMLMFSNPSNPVGSWLTADQLARVLDAT-PPETLIVVDEAY-AEYAAGDDYPSALTllkargLPWIVLRTFS 230
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 241 igsagKTFSVTGWKLGWSI-GPGHLIKHLRTVQqnsvytcaTPL---QAALAEAfwidIKRMDDPEcYFNSLPKELEVKR 316
Cdd:PRK05166 231 -----KAYGLAGLRVGYGLvSDPELVGLLDRVR--------TPFnvnGAAQAAA----LAALDDEE-HLAKGVALALAER 292
|
250 260
....*....|....*....|....*..
gi 1958752305 317 DRMACLLNSVGLKpIIPDGGYFIIADV 343
Cdd:PRK05166 293 ERLKKELAEMGYR-IAPSRANFLFFDA 318
|
|
| PRK09275 |
PRK09275 |
bifunctional aspartate transaminase/aspartate 4-decarboxylase; |
104-372 |
6.33e-05 |
|
bifunctional aspartate transaminase/aspartate 4-decarboxylase;
Pssm-ID: 236444 Cd Length: 527 Bit Score: 45.24 E-value: 6.33e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 104 LFNAIQ--GLVDPGDEVIIMVPFYDCYEPMVKMAGAVPVFIPLRSKRtdgmkwtSSDWTFNPQELESKFSSKTKAIILNT 181
Cdd:PRK09275 177 IFDSLKenGLLKAGDKIALMTPIFTPYLEIPELPRYDLEVVHINADE-------ENEWQYPDSELEKLRDPSIKALFLVN 249
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 182 PHNPIGKVYTREELQVIADLCIKH--DTLCISDEVYEWLVyTGHKHIkIATLPgmwERTITIGSAGKTFSVTGWKLGwSI 259
Cdd:PRK09275 250 PSNPPSVAMSDESLEKIADIVNEKrpDLMIITDDVYGTFV-DDFRSL-FAVLP---YNTILVYSFSKYFGATGWRLG-VI 323
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 260 GPgH-------LIKHL--------------------------------RTVQQNSVYTCATPLQA--ALAEAFWIdikrM 298
Cdd:PRK09275 324 AL-HednvfdkLIAKLpeekkkeldkrysslttdpeklkfidrlvadsRQVALNHTAGLSTPQQVqmALFSLFAL----L 398
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958752305 299 DDPECYFNSLpKELeVKRdRMACLLNSVGLKPIIP--DGGYFIIADVSSLGVDLsdvksdepYDYKFVKWMTKNKK 372
Cdd:PRK09275 399 DEEDAYKKAM-KDI-IRR-RYKALYEGLGLPEPEDpnNAAYYTLIDLEEWAEKN--------YGKEFADYLKKNYS 463
|
|
| WecE |
COG0399 |
dTDP-4-amino-4,6-dideoxygalactose transaminase [Cell wall/membrane/envelope biogenesis]; |
112-178 |
1.00e-04 |
|
dTDP-4-amino-4,6-dideoxygalactose transaminase [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440168 Cd Length: 364 Bit Score: 44.29 E-value: 1.00e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1958752305 112 VDPGDEVIimVP---FYDCYEPmVKMAGAVPVFIplrskrtDgmkwtsSD-WTFN--PQELESKFSSKTKAII 178
Cdd:COG0399 67 IGPGDEVI--TPaftFVATANA-ILYVGATPVFV-------D------IDpDTYNidPEALEAAITPRTKAII 123
|
|
| PLN02368 |
PLN02368 |
alanine transaminase |
54-220 |
1.21e-04 |
|
alanine transaminase
Pssm-ID: 177996 [Multi-domain] Cd Length: 407 Bit Score: 44.02 E-value: 1.21e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 54 AAFIDNLNQYTRGFGHPSLVKALSCLYGKIYQKQIDPnEEILVTVG---GYGSLFNAIqgLVDPGDEVIIMVPFYDCYEP 130
Cdd:PLN02368 94 SLTSGGLGAYSDSRGLPGVRKEVAEFIERRDGYPSDP-ELIFLTDGaskGVMQILNAV--IRGEKDGVLVPVPQYPLYSA 170
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 131 MVKMAGA--VPVFIPlrskrtdgmkwTSSDWTFNPQELESKFSSK------TKAIILNTPHNPIGKVYTREELQVIADLC 202
Cdd:PLN02368 171 TISLLGGtlVPYYLE-----------ESENWGLDVNNLRQSVAQArskgitVRAMVIINPGNPTGQCLSEANLREILKFC 239
|
170
....*....|....*...
gi 1958752305 203 IKHDTLCISDEVYEWLVY 220
Cdd:PLN02368 240 YQERLVLLGDEVYQQNIY 257
|
|
| PRK15407 |
PRK15407 |
lipopolysaccharide biosynthesis protein RfbH; Provisional |
114-212 |
1.70e-04 |
|
lipopolysaccharide biosynthesis protein RfbH; Provisional
Pssm-ID: 237960 Cd Length: 438 Bit Score: 43.72 E-value: 1.70e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 114 PGDEVI-IMVPFYDCYEPMVKmAGAVPVF----IPlrskrtdgmkwtssdwTFN--PQELESKFSSKTKAIILntPH--- 183
Cdd:PRK15407 110 PGDEVItVAAGFPTTVNPIIQ-NGLVPVFvdveLP----------------TYNidASLLEAAVSPKTKAIMI--AHtlg 170
|
90 100
....*....|....*....|....*....
gi 1958752305 184 NPIgkvytreELQVIADLCIKHDTLCISD 212
Cdd:PRK15407 171 NPF-------DLAAVKAFCDKHNLWLIED 192
|
|
| PLN02231 |
PLN02231 |
alanine transaminase |
89-243 |
2.34e-04 |
|
alanine transaminase
Pssm-ID: 177876 [Multi-domain] Cd Length: 534 Bit Score: 43.39 E-value: 2.34e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 89 DPNEeILVTVGGYGSLFNAIQGLV-DPGDEVIIMVPFYDCYEPMVKMAGA--VPVFIPlrskrtdgmkwTSSDWTFNPQE 165
Cdd:PLN02231 190 DPND-IFLTDGASPAVHMMMQLLIrSEKDGILCPIPQYPLYSASIALHGGtlVPYYLD-----------EATGWGLEISE 257
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 166 LESKFS-SKTK-----AIILNTPHNPIGKVYTREELQVIADLCIKHDTLCISDEVYEWLVYTGHKHI----KIATLPGMW 235
Cdd:PLN02231 258 LKKQLEdARSKgitvrALVVINPGNPTGQVLAEENQRDIVEFCKQEGLVLLADEVYQENVYVPDKKFhsfkKVARSMGYG 337
|
....*...
gi 1958752305 236 ERTITIGS 243
Cdd:PLN02231 338 EKDISLVS 345
|
|
| PRK08637 |
PRK08637 |
hypothetical protein; Provisional |
112-220 |
1.32e-03 |
|
hypothetical protein; Provisional
Pssm-ID: 181512 Cd Length: 388 Bit Score: 40.71 E-value: 1.32e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 112 VDPGDEVIIMVPFYDCYEPMVK-MAGAVPVFIPLRSKR----TDGMKwtssdwtfnpQELESKFSSKTKAIILNTPHNPI 186
Cdd:PRK08637 90 VDQGDTVLLPDHNWGNYKLTFNtRRGAEIVTYPIFDEDggfdTDALK----------EALQAAYNKGKVIVILNFPNNPT 159
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 1958752305 187 GKVYTREELQVIADLcIKH------DTLCISDEVYEWLVY 220
Cdd:PRK08637 160 GYTPTEKEATAIVEA-IKEladagtKVVAVVDDAYFGLFY 198
|
|
| PRK08354 |
PRK08354 |
putative aminotransferase; Provisional |
44-260 |
1.73e-03 |
|
putative aminotransferase; Provisional
Pssm-ID: 169399 Cd Length: 311 Bit Score: 40.10 E-value: 1.73e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 44 PSYVQEELSKAAFIDNLNQYTRGfghpsLVKALSCLYGkiyqkqidpnEEILVTVGGYGSLFnAIQGLVDPGDEVIIMVP 123
Cdd:PRK08354 22 PEWLDEMFERAKEISGRYTYYEW-----LEEEFSKLFG----------EPIVITAGITEALY-LIGILALRDRKVIIPRH 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 124 FYDCYEPMVKMAGAVPVFIPLrskrtdgmkwtssdwtfNPQELEsKFSSKTKAIILNTPHNPIGKVYTREELQVIADLCI 203
Cdd:PRK08354 86 TYGEYERVARFFAARIIKGPN-----------------DPEKLE-ELVERNSVVFFCNPNNPDGKFYNFKELKPLLDAVE 147
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1958752305 204 KHDTLCISDEVYEWLV-----YTGHKHIKIatlpgmweRTITigsagKTFSVTGWKLGWSIG 260
Cdd:PRK08354 148 DRNALLILDEAFIDFVkkpesPEGENIIKL--------RTFT-----KSYGLPGIRVGYVKG 196
|
|
| PRK08247 |
PRK08247 |
methionine biosynthesis PLP-dependent protein; |
160-212 |
2.70e-03 |
|
methionine biosynthesis PLP-dependent protein;
Pssm-ID: 181320 [Multi-domain] Cd Length: 366 Bit Score: 39.69 E-value: 2.70e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 1958752305 160 TFNPQELESKFSSKTKAIILNTPHNPIGKVytrEELQVIADLCIKHDTLCISD 212
Cdd:PRK08247 123 TASLKAIEQAITPNTKAIFIETPTNPLMQE---TDIAAIAKIAKKHGLLLIVD 172
|
|
| PRK07503 |
PRK07503 |
methionine gamma-lyase; Provisional |
92-215 |
3.49e-03 |
|
methionine gamma-lyase; Provisional
Pssm-ID: 181005 [Multi-domain] Cd Length: 403 Bit Score: 39.40 E-value: 3.49e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 92 EEILVTVGGYGSLFNAIQGLVDPGDEVIIMVPFYDCyepmvkmagavpVFIPLRSKRTD-GMKWTSSDWTfNPQELESKF 170
Cdd:PRK07503 81 EAAVALASGMGAITATLWTLLRPGDEVIVDQTLYGC------------TFAFLHHGLGEfGVTVRHVDLT-DPAALKAAI 147
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 1958752305 171 SSKTKAIILNTPHNPIGKVYtreELQVIADLCIKHDTLCISDEVY 215
Cdd:PRK07503 148 SDKTRMVYFETPANPNMRLV---DIAAVAEIAHGAGAKVVVDNTY 189
|
|
| CGS_like |
cd00614 |
CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed ... |
45-212 |
3.73e-03 |
|
CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of antimicrobials and herbicides. This subgroup also includes cystathionine gamma-lyases (CGL), O-acetylhomoserine sulfhydrylases and O-acetylhomoserine thiol lyases. CGL's are very similar to CGS's. Members of this group are widely distributed among all three forms of life.
Pssm-ID: 99738 [Multi-domain] Cd Length: 369 Bit Score: 39.11 E-value: 3.73e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 45 SYVQEELSKAAFIDNL----NQYTRGfGHP---SLVKALSCLYGkiyqkqidpNEEILVTVGGYGSLFNAIQGLVDPGDE 117
Cdd:cd00614 12 TFVFPSPAEAADLFALreggYIYSRI-GNPtvdALEKKLAALEG---------GEAALAFSSGMAAISTVLLALLKAGDH 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 118 ViimVPFYDCYepmvkmaGAVPVFIPLRSKRTdGMKWTSSDwTFNPQELESKFSSKTKAIILNTPHNPIGKVYtreELQV 197
Cdd:cd00614 82 V---VASDDLY-------GGTYRLFERLLPKL-GIEVTFVD-PDDPEALEAAIKPETKLVYVESPTNPTLKVV---DIEA 146
|
170
....*....|....*
gi 1958752305 198 IADLCIKHDTLCISD 212
Cdd:cd00614 147 IAELAHEHGALLVVD 161
|
|
| AHBA_syn |
cd00616 |
3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal ... |
112-178 |
5.41e-03 |
|
3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary metabolites. Some well studied proteins in this CD are AHBA_synthase, protein product of pleiotropic regulatory gene degT, Arnb aminotransferase and pilin glycosylation protein. The prototype of this family, the AHBA_synthase, is a dimeric PLP dependent enzyme. AHBA_syn is the terminal enzyme of 3-amino-5-hydroxybenzoic acid (AHBA) formation which is involved in the biosynthesis of ansamycin antibiotics, including rifamycin B. Some members of this CD are involved in 4-amino-6-deoxy-monosaccharide D-perosamine synthesis. Perosamine is an important element in the glycosylation of several cell products, such as antibiotics and lipopolysaccharides of gram-positive and gram-negative bacteria. The pilin glycosylation protein encoded by gene pglA, is a galactosyltransferase involved in pilin glycosylation. Additionally, this CD consists of ArnB (PmrH) aminotransferase, a 4-amino-4-deoxy-L-arabinose lipopolysaccharide-modifying enzyme. This CD also consists of several predicted pyridoxal phosphate-dependent enzymes apparently involved in regulation of cell wall biogenesis. The catalytic lysine which is present in all characterized PLP dependent enzymes is replaced by histidine in some members of this CD.
Pssm-ID: 99740 [Multi-domain] Cd Length: 352 Bit Score: 38.68 E-value: 5.41e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1958752305 112 VDPGDEVIimVPfydcyePM--------VKMAGAVPVFI---PlrskrtdgmkwtsSDWTFNPQELESKFSSKTKAII 178
Cdd:cd00616 55 IGPGDEVI--VP------SFtfvatanaILLLGATPVFVdidP-------------DTYNIDPELIEAAITPRTKAII 111
|
|
| DegT_DnrJ_EryC1 |
pfam01041 |
DegT/DnrJ/EryC1/StrS aminotransferase family; The members of this family are probably all ... |
112-212 |
6.37e-03 |
|
DegT/DnrJ/EryC1/StrS aminotransferase family; The members of this family are probably all pyridoxal-phosphate-dependent aminotransferase enzymes with a variety of molecular functions. The family includes StsA, StsC and StsS. The aminotransferase activity was demonstrated for purified StsC protein as the L-glutamine:scyllo-inosose aminotransferase EC:2.6.1.50, which catalyzes the first amino transfer in the biosynthesis of the streptidine subunit of streptomycin.
Pssm-ID: 395827 Cd Length: 360 Bit Score: 38.42 E-value: 6.37e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752305 112 VDPGDEVIiMVPF-YDCYEPMVKMAGAVPVFIPLRSKrtdgmkwtssDWTFNPQELESKFSSKTKAIIlntPHNPIGKVY 190
Cdd:pfam01041 61 VGPGDEVI-TPSFtFVATANAALRLGAKPVFVDIDPD----------TYNIDPEAIEAAITPRTKAII---PVHLYGQPA 126
|
90 100
....*....|....*....|..
gi 1958752305 191 treELQVIADLCIKHDTLCISD 212
Cdd:pfam01041 127 ---DMDAIRAIAARHGLPVIED 145
|
|
| |
