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Conserved domains on  [gi|1958660523|ref|XP_038942607|]
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nuclear receptor corepressor 1 isoform X5 [Rattus norvegicus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
GPS2_interact super family cl24372
G-protein pathway suppressor 2-interacting domain; GPS2_interact is the more N-terminal domain ...
 162-251 2.04e-27

G-protein pathway suppressor 2-interacting domain; GPS2_interact is the more N-terminal domain of two co-repressor protein-families found in vertebrates. The domain is found in NCoR and SMRT proteins; N-CoR (nuclear receptor co-repressor) and SMRT (silencing mediator for retinoid and thyroid receptors) are related corepressors that mediate transcriptional repression by unliganded nuclear receptors and other classes of transcriptional repressors. GPS2 is a stoichiometric subunit of the N-CoR-HDAC3 complex. GPS2 links the complex to membrane receptor-related intracellular JNK (c-Jun amino-terminal kinase) signalling pathways.


The actual alignment was detected with superfamily member pfam15784:

Pssm-ID: 464868 [Multi-domain]  Cd Length: 89  Bit Score: 107.64  E-value: 2.04e-27
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958660523  162 FGGKHEAPSSPLAGqPCGDDQNASPSKLSKEELIQSMDRVDREIAKVEQQILKLKKKQQQLEEEAAKPPEPEKPVSPPPV 241
Cdd:pfam15784    1 YYPQVEAISPTLPS-PEGQDQELSPFRSSKDELLQNIDKVDREIAKVEQQISKLKKKQQQLEEEAAKPPEPEEPVSPPPS 79

                           90
                   ....*....|
gi 1958660523  242 EQKHRSIVQI 251
Cdd:pfam15784   80 ESKHRSLAQI 89
Myb_DNA-binding pfam00249
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 649-692 6.47e-12

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


:

Pssm-ID: 459731 [Multi-domain]  Cd Length: 46  Bit Score: 62.14  E-value: 6.47e-12
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....
gi 1958660523  649 RWTEEEMEVAKKGLVEHGRNWAAIAKMVGTKSEAQCKNFYFNYK 692
Cdd:pfam00249    3 PWTPEEDELLLEAVEKLGNRWKKIAKLLPGRTDNQCKNRWQNYL 46
LGT super family cl00478
Prolipoprotein diacylglyceryl transferase;
772-938 4.01e-05

Prolipoprotein diacylglyceryl transferase;


The actual alignment was detected with superfamily member PRK13108:

Pssm-ID: 469786 [Multi-domain]  Cd Length: 460  Bit Score: 48.82  E-value: 4.01e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958660523  772 VEAAKSSEDSsenAASRGN---TEPVAELEATTDPAPC-ASPSSAVPTTKPAESESVEAqVTDSASVETAEPMDVDHEEC 847
Cdd:PRK13108   273 ILAPKGREAP---GALRGSeyvVDEALEREPAELAAAAvASAASAVGPVGPGEPNQPDD-VAEAVKAEVAEVTDEVAAES 348

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958660523  848 GAQGSSVLDPPAPTKADSVDPEIQVPENTASKGEGDAKDR---------DLESASEKTEARDEDLVVAEQMQRPEPQSDN 918
Cdd:PRK13108   349 VVQVADRDGESTPAVEETSEADIEREQPGDLAGQAPAAHQvdaeaasaaPEEPAALASEAHDETEPEVPEKAAPIPDPAK 428

                          170       180
                   ....*....|....*....|
gi 1958660523  919 DSSATCSADEDVDGEPERQR 938
Cdd:PRK13108   429 PDELAVAGPGDDPAEPDGIR 448
SANT cd00167
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ...
 462-504 1.33e-04

'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.


:

Pssm-ID: 238096 [Multi-domain]  Cd Length: 45  Bit Score: 41.41  E-value: 1.33e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....
gi 1958660523  462 WTDHEKEIFKDKFIQHP-KNFGLIASYLERKSVPDCVLYYYLTK 504
Cdd:cd00167      2 WTEEEDELLLEAVKKYGkNNWEKIAKELPGRTPKQCRERWRNLL 45
PRK10263 super family cl35903
DNA translocase FtsK; Provisional
 2087-2272 2.28e-03

DNA translocase FtsK; Provisional


The actual alignment was detected with superfamily member PRK10263:

Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 43.54  E-value: 2.28e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958660523 2087 YEAPSDAIEVISPASSPAPPQEKPQ-AYQP-------EMVKANQAENESPQ-QYEGPLHHYRSQQGSPSPQQQPPLPPSS 2157
Cdd:PRK10263   333 WAAPVEPVTQTPPVASVDVPPAQPTvAWQPvpgpqtgEPVIAPAPEGYPQQsQYAQPAVQYNEPLQQPVQPQQPYYAPAA 412

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958660523 2158 QAEGMGQVPRTHRLITLA-DHICQIITQDFARNQVPSQPSTSTFQTSPSALSSTPVrTKPSSRYSPESQSQTVlhpRPGP 2236
Cdd:PRK10263   413 EQPAQQPYYAPAPEQPAQqPYYAPAPEQPVAGNAWQAEEQQSTFAPQSTYQTEQTY-QQPAAQEPLYQQPQPV---EQQP 488

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*.
gi 1958660523 2237 RVSPENLVDKSRGSRP----------GKSPERSHIPSEpYEPISPP 2272
Cdd:PRK10263   489 VVEPEPVVEETKPARPplyyfeeveeKRAREREQLAAW-YQPIPEP 533
 
Name Accession Description Interval E-value
GPS2_interact pfam15784
G-protein pathway suppressor 2-interacting domain; GPS2_interact is the more N-terminal domain ...
 162-251 2.04e-27

G-protein pathway suppressor 2-interacting domain; GPS2_interact is the more N-terminal domain of two co-repressor protein-families found in vertebrates. The domain is found in NCoR and SMRT proteins; N-CoR (nuclear receptor co-repressor) and SMRT (silencing mediator for retinoid and thyroid receptors) are related corepressors that mediate transcriptional repression by unliganded nuclear receptors and other classes of transcriptional repressors. GPS2 is a stoichiometric subunit of the N-CoR-HDAC3 complex. GPS2 links the complex to membrane receptor-related intracellular JNK (c-Jun amino-terminal kinase) signalling pathways.


Pssm-ID: 464868 [Multi-domain]  Cd Length: 89  Bit Score: 107.64  E-value: 2.04e-27
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958660523  162 FGGKHEAPSSPLAGqPCGDDQNASPSKLSKEELIQSMDRVDREIAKVEQQILKLKKKQQQLEEEAAKPPEPEKPVSPPPV 241
Cdd:pfam15784    1 YYPQVEAISPTLPS-PEGQDQELSPFRSSKDELLQNIDKVDREIAKVEQQISKLKKKQQQLEEEAAKPPEPEEPVSPPPS 79

                           90
                   ....*....|
gi 1958660523  242 EQKHRSIVQI 251
Cdd:pfam15784   80 ESKHRSLAQI 89
Myb_DNA-binding pfam00249
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 649-692 6.47e-12

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 459731 [Multi-domain]  Cd Length: 46  Bit Score: 62.14  E-value: 6.47e-12
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....
gi 1958660523  649 RWTEEEMEVAKKGLVEHGRNWAAIAKMVGTKSEAQCKNFYFNYK 692
Cdd:pfam00249    3 PWTPEEDELLLEAVEKLGNRWKKIAKLLPGRTDNQCKNRWQNYL 46
SANT cd00167
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ...
 649-692 1.40e-10

'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.


Pssm-ID: 238096 [Multi-domain]  Cd Length: 45  Bit Score: 58.36  E-value: 1.40e-10
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*
gi 1958660523  649 RWTEEEMEVAKKGLVEHG-RNWAAIAKMVGTKSEAQCKNFYFNYK 692
Cdd:cd00167      1 PWTEEEDELLLEAVKKYGkNNWEKIAKELPGRTPKQCRERWRNLL 45
SANT smart00717
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;
649-694 2.23e-10

SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;


Pssm-ID: 197842 [Multi-domain]  Cd Length: 49  Bit Score: 58.00  E-value: 2.23e-10
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*..
gi 1958660523   649 RWTEEEMEVAKKGLVEHG-RNWAAIAKMVGTKSEAQCKNFYFNYKRR 694
Cdd:smart00717    3 EWTEEEDELLIELVKKYGkNNWEKIAKELPGRTAEQCRERWRNLLKP 49
PRK13108 PRK13108
prolipoprotein diacylglyceryl transferase; Reviewed
 772-938 4.01e-05

prolipoprotein diacylglyceryl transferase; Reviewed


Pssm-ID: 237284 [Multi-domain]  Cd Length: 460  Bit Score: 48.82  E-value: 4.01e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958660523  772 VEAAKSSEDSsenAASRGN---TEPVAELEATTDPAPC-ASPSSAVPTTKPAESESVEAqVTDSASVETAEPMDVDHEEC 847
Cdd:PRK13108   273 ILAPKGREAP---GALRGSeyvVDEALEREPAELAAAAvASAASAVGPVGPGEPNQPDD-VAEAVKAEVAEVTDEVAAES 348

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958660523  848 GAQGSSVLDPPAPTKADSVDPEIQVPENTASKGEGDAKDR---------DLESASEKTEARDEDLVVAEQMQRPEPQSDN 918
Cdd:PRK13108   349 VVQVADRDGESTPAVEETSEADIEREQPGDLAGQAPAAHQvdaeaasaaPEEPAALASEAHDETEPEVPEKAAPIPDPAK 428

                          170       180
                   ....*....|....*....|
gi 1958660523  919 DSSATCSADEDVDGEPERQR 938
Cdd:PRK13108   429 PDELAVAGPGDDPAEPDGIR 448
MDN1 COG5271
Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal ...
 724-935 4.58e-05

Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444083 [Multi-domain]  Cd Length: 1028  Bit Score: 49.24  E-value: 4.58e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958660523  724 VSQCESVASTVSAQEDEDIEASNEEENPEDSEGAEN--------SSDTESAPSP-SPVEAAKSSEDSSENAASRGNTEPV 794
Cdd:COG5271    589 ESADESEEAEASEDEAAEEEEADDDEADADADGAADeeeteeeaAEDEAAEPETdASEAADEDADAETEAEASADESEEE 668

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958660523  795 AELEATTDPAPCASPSSAVPTTKPAESESVEA---------QVTDSASVETAEPMDVDHEECGAQGSSVLDPPA---PTK 862
Cdd:COG5271    669 AEDESETSSEDAEEDADAAAAEASDDEEETEEadedaetasEEADAEEADTEADGTAEEAEEAAEEAESADEEAaslPDE 748

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1958660523  863 ADSVDPEIQVPENTASKGEGDAKDRDLESASEKTEARDEDLVVAEqmqrPEPQSDNDSSATCSADEDVDGEPE 935
Cdd:COG5271    749 ADAEEEAEEAEEAEEDDADGLEEALEEEKADAEEAATDEEAEAAA----EEKEKVADEDQDTDEDALLDEAEA 817
SANT cd00167
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ...
 462-504 1.33e-04

'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.


Pssm-ID: 238096 [Multi-domain]  Cd Length: 45  Bit Score: 41.41  E-value: 1.33e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....
gi 1958660523  462 WTDHEKEIFKDKFIQHP-KNFGLIASYLERKSVPDCVLYYYLTK 504
Cdd:cd00167      2 WTEEEDELLLEAVKKYGkNNWEKIAKELPGRTPKQCRERWRNLL 45
SANT smart00717
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;
460-505 4.12e-04

SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;


Pssm-ID: 197842 [Multi-domain]  Cd Length: 49  Bit Score: 40.28  E-value: 4.12e-04
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*..
gi 1958660523   460 NVWTDHEKEIFKDKFIQHP-KNFGLIASYLERKSVPDCVLYYYLTKK 505
Cdd:smart00717    2 GEWTEEEDELLIELVKKYGkNNWEKIAKELPGRTAEQCRERWRNLLK 48
Myb_DNA-binding pfam00249
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 462-501 5.48e-04

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 459731 [Multi-domain]  Cd Length: 46  Bit Score: 39.79  E-value: 5.48e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 1958660523  462 WTDHEKEIFKDKFIQHPKNFGLIASYLERKSVPDCVLYYY 501
Cdd:pfam00249    4 WTPEEDELLLEAVEKLGNRWKKIAKLLPGRTDNQCKNRWQ 43
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 2087-2272 2.28e-03

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 43.54  E-value: 2.28e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958660523 2087 YEAPSDAIEVISPASSPAPPQEKPQ-AYQP-------EMVKANQAENESPQ-QYEGPLHHYRSQQGSPSPQQQPPLPPSS 2157
Cdd:PRK10263   333 WAAPVEPVTQTPPVASVDVPPAQPTvAWQPvpgpqtgEPVIAPAPEGYPQQsQYAQPAVQYNEPLQQPVQPQQPYYAPAA 412

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958660523 2158 QAEGMGQVPRTHRLITLA-DHICQIITQDFARNQVPSQPSTSTFQTSPSALSSTPVrTKPSSRYSPESQSQTVlhpRPGP 2236
Cdd:PRK10263   413 EQPAQQPYYAPAPEQPAQqPYYAPAPEQPVAGNAWQAEEQQSTFAPQSTYQTEQTY-QQPAAQEPLYQQPQPV---EQQP 488

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*.
gi 1958660523 2237 RVSPENLVDKSRGSRP----------GKSPERSHIPSEpYEPISPP 2272
Cdd:PRK10263   489 VVEPEPVVEETKPARPplyyfeeveeKRAREREQLAAW-YQPIPEP 533
AIF-MLS pfam14962
Mitochondria localization Sequence; This family contains a protein found in eukaryotes. ...
 747-867 6.83e-03

Mitochondria localization Sequence; This family contains a protein found in eukaryotes. Proteins in this family are typically between 240 and 613 amino acids in length. The family is found in association with pfam07992. This protein family is an N-terminal domain for the mitochondrial localization sequence for an apoptosis-inducing factor. The protein is also known as Corneal endothelium-specific protein 1 or as Ovary-specific acidic protein. It is thought to be important for membrane function and is expressed in the ovary and corneal endothelium.


Pssm-ID: 464407 [Multi-domain]  Cd Length: 192  Bit Score: 40.20  E-value: 6.83e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958660523  747 EEENPEDSEGAenSSDtesAPSPSPVEAakSSEDSSENaasrgntePVAELEATTDPAPCASPSSAVPTTKPAESESVEA 826
Cdd:pfam14962   95 EKENVAEAEKA--SSE---APEVSVVEA--EVVDAEEI--------PDATAAVIEEASACPGDVEAAPVETTAVGAETGP 159

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|.
gi 1958660523  827 QVTDSASVETAepmdvdheECGAQGSSVLDPPAPTKADSVD 867
Cdd:pfam14962  160 EVTDAATGETT--------EVSAETTPEVTSAAPDEAVAID 192
 
Name Accession Description Interval E-value
GPS2_interact pfam15784
G-protein pathway suppressor 2-interacting domain; GPS2_interact is the more N-terminal domain ...
 162-251 2.04e-27

G-protein pathway suppressor 2-interacting domain; GPS2_interact is the more N-terminal domain of two co-repressor protein-families found in vertebrates. The domain is found in NCoR and SMRT proteins; N-CoR (nuclear receptor co-repressor) and SMRT (silencing mediator for retinoid and thyroid receptors) are related corepressors that mediate transcriptional repression by unliganded nuclear receptors and other classes of transcriptional repressors. GPS2 is a stoichiometric subunit of the N-CoR-HDAC3 complex. GPS2 links the complex to membrane receptor-related intracellular JNK (c-Jun amino-terminal kinase) signalling pathways.


Pssm-ID: 464868 [Multi-domain]  Cd Length: 89  Bit Score: 107.64  E-value: 2.04e-27
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958660523  162 FGGKHEAPSSPLAGqPCGDDQNASPSKLSKEELIQSMDRVDREIAKVEQQILKLKKKQQQLEEEAAKPPEPEKPVSPPPV 241
Cdd:pfam15784    1 YYPQVEAISPTLPS-PEGQDQELSPFRSSKDELLQNIDKVDREIAKVEQQISKLKKKQQQLEEEAAKPPEPEEPVSPPPS 79

                           90
                   ....*....|
gi 1958660523  242 EQKHRSIVQI 251
Cdd:pfam15784   80 ESKHRSLAQI 89
Myb_DNA-binding pfam00249
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 649-692 6.47e-12

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 459731 [Multi-domain]  Cd Length: 46  Bit Score: 62.14  E-value: 6.47e-12
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....
gi 1958660523  649 RWTEEEMEVAKKGLVEHGRNWAAIAKMVGTKSEAQCKNFYFNYK 692
Cdd:pfam00249    3 PWTPEEDELLLEAVEKLGNRWKKIAKLLPGRTDNQCKNRWQNYL 46
SANT cd00167
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ...
 649-692 1.40e-10

'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.


Pssm-ID: 238096 [Multi-domain]  Cd Length: 45  Bit Score: 58.36  E-value: 1.40e-10
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*
gi 1958660523  649 RWTEEEMEVAKKGLVEHG-RNWAAIAKMVGTKSEAQCKNFYFNYK 692
Cdd:cd00167      1 PWTEEEDELLLEAVKKYGkNNWEKIAKELPGRTPKQCRERWRNLL 45
SANT smart00717
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;
649-694 2.23e-10

SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;


Pssm-ID: 197842 [Multi-domain]  Cd Length: 49  Bit Score: 58.00  E-value: 2.23e-10
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*..
gi 1958660523   649 RWTEEEMEVAKKGLVEHG-RNWAAIAKMVGTKSEAQCKNFYFNYKRR 694
Cdd:smart00717    3 EWTEEEDELLIELVKKYGkNNWEKIAKELPGRTAEQCRERWRNLLKP 49
PRK13108 PRK13108
prolipoprotein diacylglyceryl transferase; Reviewed
 772-938 4.01e-05

prolipoprotein diacylglyceryl transferase; Reviewed


Pssm-ID: 237284 [Multi-domain]  Cd Length: 460  Bit Score: 48.82  E-value: 4.01e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958660523  772 VEAAKSSEDSsenAASRGN---TEPVAELEATTDPAPC-ASPSSAVPTTKPAESESVEAqVTDSASVETAEPMDVDHEEC 847
Cdd:PRK13108   273 ILAPKGREAP---GALRGSeyvVDEALEREPAELAAAAvASAASAVGPVGPGEPNQPDD-VAEAVKAEVAEVTDEVAAES 348

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958660523  848 GAQGSSVLDPPAPTKADSVDPEIQVPENTASKGEGDAKDR---------DLESASEKTEARDEDLVVAEQMQRPEPQSDN 918
Cdd:PRK13108   349 VVQVADRDGESTPAVEETSEADIEREQPGDLAGQAPAAHQvdaeaasaaPEEPAALASEAHDETEPEVPEKAAPIPDPAK 428

                          170       180
                   ....*....|....*....|
gi 1958660523  919 DSSATCSADEDVDGEPERQR 938
Cdd:PRK13108   429 PDELAVAGPGDDPAEPDGIR 448
MDN1 COG5271
Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal ...
 724-935 4.58e-05

Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444083 [Multi-domain]  Cd Length: 1028  Bit Score: 49.24  E-value: 4.58e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958660523  724 VSQCESVASTVSAQEDEDIEASNEEENPEDSEGAEN--------SSDTESAPSP-SPVEAAKSSEDSSENAASRGNTEPV 794
Cdd:COG5271    589 ESADESEEAEASEDEAAEEEEADDDEADADADGAADeeeteeeaAEDEAAEPETdASEAADEDADAETEAEASADESEEE 668

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958660523  795 AELEATTDPAPCASPSSAVPTTKPAESESVEA---------QVTDSASVETAEPMDVDHEECGAQGSSVLDPPA---PTK 862
Cdd:COG5271    669 AEDESETSSEDAEEDADAAAAEASDDEEETEEadedaetasEEADAEEADTEADGTAEEAEEAAEEAESADEEAaslPDE 748

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1958660523  863 ADSVDPEIQVPENTASKGEGDAKDRDLESASEKTEARDEDLVVAEqmqrPEPQSDNDSSATCSADEDVDGEPE 935
Cdd:COG5271    749 ADAEEEAEEAEEAEEDDADGLEEALEEEKADAEEAATDEEAEAAA----EEKEKVADEDQDTDEDALLDEAEA 817
MDN1 COG5271
Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal ...
 730-937 4.98e-05

Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444083 [Multi-domain]  Cd Length: 1028  Bit Score: 48.86  E-value: 4.98e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958660523  730 VASTVSAQEDEDIEASNEEENPEDSEGAENSSDTESAPSPSPVEAAKSSEDSSENAASRGNTEPVAE------------- 796
Cdd:COG5271    436 VTSAEDDIATDEEADSLADEEEEAEAELDTEEDTESAEEDADGDEATDEDDASDDGDEEEAEEDAEAeadsdeltaeets 515

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958660523  797 --LEATTDPAPcASPSSAVPTTKPAESESVEAQVTDSASVETAEPMDVDHEECGAQGSS-VLDPPAPTKADSVDPEIQvp 873
Cdd:COG5271    516 adDGADTDAAA-DPEDSDEDALEDETEGEENAPGSDQDADETDEPEATAEEDEPDEAEAeTEDATENADADETEESAD-- 592

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1958660523  874 ENTASKGEGDAKDRDLESASEKTEAR-----DEDLVVAEQMQRPEPQSDNDSSATCSADEDVDGEPERQ 937
Cdd:COG5271    593 ESEEAEASEDEAAEEEEADDDEADADadgaaDEEETEEEAAEDEAAEPETDASEAADEDADAETEAEAS 661
MDN1 COG5271
Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal ...
 715-935 8.63e-05

Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444083 [Multi-domain]  Cd Length: 1028  Bit Score: 48.09  E-value: 8.63e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958660523  715 SRKPREERDVSQCESVASTVSAQEDEDIEASNEEE-------NPEDSEGAENSSDTE------SAPSPSPVEAAKSSEDS 781
Cdd:COG5271    524 AAADPEDSDEDALEDETEGEENAPGSDQDADETDEpeataeeDEPDEAEAETEDATEnadadeTEESADESEEAEASEDE 603

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958660523  782 SENAASRGNTEPVAELEATTDPAPCASPSSAVPtTKPAESESVEAQVTDSASVETAEPmDVDHEECGAQgssvLDPPAPT 861
Cdd:COG5271    604 AAEEEEADDDEADADADGAADEEETEEEAAEDE-AAEPETDASEAADEDADAETEAEA-SADESEEEAE----DESETSS 677

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1958660523  862 KADSVDPEIQVPENTASKGEGDAKDRDLESASEKTEARDEDlvvaEQMQRPEPQSDNDSSATCSADEDVDGEPE 935
Cdd:COG5271    678 EDAEEDADAAAAEASDDEEETEEADEDAETASEEADAEEAD----TEADGTAEEAEEAAEEAESADEEAASLPD 747
SANT cd00167
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ...
 462-504 1.33e-04

'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.


Pssm-ID: 238096 [Multi-domain]  Cd Length: 45  Bit Score: 41.41  E-value: 1.33e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....
gi 1958660523  462 WTDHEKEIFKDKFIQHP-KNFGLIASYLERKSVPDCVLYYYLTK 504
Cdd:cd00167      2 WTEEEDELLLEAVKKYGkNNWEKIAKELPGRTPKQCRERWRNLL 45
SANT smart00717
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;
460-505 4.12e-04

SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;


Pssm-ID: 197842 [Multi-domain]  Cd Length: 49  Bit Score: 40.28  E-value: 4.12e-04
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*..
gi 1958660523   460 NVWTDHEKEIFKDKFIQHP-KNFGLIASYLERKSVPDCVLYYYLTKK 505
Cdd:smart00717    2 GEWTEEEDELLIELVKKYGkNNWEKIAKELPGRTAEQCRERWRNLLK 48
Myb_DNA-binding pfam00249
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 462-501 5.48e-04

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 459731 [Multi-domain]  Cd Length: 46  Bit Score: 39.79  E-value: 5.48e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 1958660523  462 WTDHEKEIFKDKFIQHPKNFGLIASYLERKSVPDCVLYYY 501
Cdd:pfam00249    4 WTPEEDELLLEAVEKLGNRWKKIAKLLPGRTDNQCKNRWQ 43
MDN1 COG5271
Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal ...
 733-935 8.14e-04

Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444083 [Multi-domain]  Cd Length: 1028  Bit Score: 45.01  E-value: 8.14e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958660523  733 TVSAQEDEDIEASNEEENPEDSEGAENSSDTESAPSPSPVEAAKSSEDSSENAASRGNTEPVAELEATTDPAPCASPSSA 812
Cdd:COG5271    266 GTPDTDDEATDDADGLEAAEDDALDAELTAAQAADPESDDDADDSTLAALEGAAEDTEIATADELAAADDEDDDDSAAED 345

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958660523  813 VPTTKPAESESVEAQVTDSASVETAEPMDVDHEECGAQGSSVLDPPAPTKADSVDPEIQVPENTASKGEGDAKDRDLESA 892
Cdd:COG5271    346 AAEEAATAEDSAAEDTQDAEDEAAGEAADESEGADTDAAADEADAAADDSADDEEASADGGTSPTSDTDEEEEEADEDAS 425

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|...
gi 1958660523  893 SEKTEARDEDLVVAEQMqrpepqSDNDSSATCSADEDVDGEPE 935
Cdd:COG5271    426 AGETEDESTDVTSAEDD------IATDEEADSLADEEEEAEAE 462
SANT_MTA3_like cd11661
Myb-Like Dna-Binding Domain of MTA3 and related proteins; Members in this SANT/myb family ...
 462-505 1.01e-03

Myb-Like Dna-Binding Domain of MTA3 and related proteins; Members in this SANT/myb family include domains found in mouse metastasis-associated protein 3 (MTA3) proteins and arginine-glutamic dipeptide (RERE) repeats proteins. SANT (SWI3, ADA2, N-CoR and TFIIIB) DNA-binding domains are a diverse set of proteins that share a common 3 alpha-helix bundle. MTA3 has been shown to interact with nucleosome remodeling and deacetylase (NuRD) proteins CHD4 and HDAC1, and the core cohesin complex protein RAD21 in the ovary, and regulate G2/M progression in proliferating granulosa cells. RERE belongs to the atrophin family and has been identified as a nuclear receptor corepressor; altered expression levels of RERE are associated with cancer in humans while mutations of Rere in mice cause failure in closing the anterior neural tube and fusion of the telencephalic and optic vesicles during embryogenesis.


Pssm-ID: 212559 [Multi-domain]  Cd Length: 46  Bit Score: 39.13  E-value: 1.01e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*
gi 1958660523  462 WTDHEKEIFKDKFIQHPKNFGLI-ASYLERKSVPDCVLYYYLTKK 505
Cdd:cd11661      2 WSESEAKLFEEGLRKYGKDFHDIrQDFLPWKSVGELVEFYYMWKK 46
PRK13108 PRK13108
prolipoprotein diacylglyceryl transferase; Reviewed
 742-898 1.43e-03

prolipoprotein diacylglyceryl transferase; Reviewed


Pssm-ID: 237284 [Multi-domain]  Cd Length: 460  Bit Score: 43.81  E-value: 1.43e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958660523  742 IEASNEEENPEDSEGAENSSDTESAPSPSPVEAAKSSEDSSENAASRGNT------------EPVAELEATTDPAPCASP 809
Cdd:PRK13108   273 ILAPKGREAPGALRGSEYVVDEALEREPAELAAAAVASAASAVGPVGPGEpnqpddvaeavkAEVAEVTDEVAAESVVQV 352

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958660523  810 SSAVPTTKPAESESVEAQVTDSASVETAEPMDVDHEECGAQGSSvlDPPAPTKADSVDPEIQVPEnTASKGEGDA-KDRD 888
Cdd:PRK13108   353 ADRDGESTPAVEETSEADIEREQPGDLAGQAPAAHQVDAEAASA--APEEPAALASEAHDETEPE-VPEKAAPIPdPAKP 429

                          170
                   ....*....|
gi 1958660523  889 LESASEKTEA 898
Cdd:PRK13108   430 DELAVAGPGD 439
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 2087-2272 2.28e-03

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 43.54  E-value: 2.28e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958660523 2087 YEAPSDAIEVISPASSPAPPQEKPQ-AYQP-------EMVKANQAENESPQ-QYEGPLHHYRSQQGSPSPQQQPPLPPSS 2157
Cdd:PRK10263   333 WAAPVEPVTQTPPVASVDVPPAQPTvAWQPvpgpqtgEPVIAPAPEGYPQQsQYAQPAVQYNEPLQQPVQPQQPYYAPAA 412

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958660523 2158 QAEGMGQVPRTHRLITLA-DHICQIITQDFARNQVPSQPSTSTFQTSPSALSSTPVrTKPSSRYSPESQSQTVlhpRPGP 2236
Cdd:PRK10263   413 EQPAQQPYYAPAPEQPAQqPYYAPAPEQPVAGNAWQAEEQQSTFAPQSTYQTEQTY-QQPAAQEPLYQQPQPV---EQQP 488

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*.
gi 1958660523 2237 RVSPENLVDKSRGSRP----------GKSPERSHIPSEpYEPISPP 2272
Cdd:PRK10263   489 VVEPEPVVEETKPARPplyyfeeveeKRAREREQLAAW-YQPIPEP 533
Myb_DNA-bind_6 pfam13921
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 650-697 2.83e-03

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 372817 [Multi-domain]  Cd Length: 60  Bit Score: 38.06  E-value: 2.83e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*...
gi 1958660523  650 WTEEEMEVAKKGLVEHGRNWAAIAKMVGTKSEAQCKnFYFNYKRRHNL 697
Cdd:pfam13921    1 WTEEEDEKLLKLVEKYGNDWKQIAKELGRRTPKQCF-DRWRRKLNPKI 47
PRK11907 PRK11907
bifunctional 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase;
729-836 3.78e-03

bifunctional 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase;


Pssm-ID: 237019 [Multi-domain]  Cd Length: 814  Bit Score: 42.53  E-value: 3.78e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958660523  729 SVASTVSAQEDEDIEASNEEENPEDSEGAENSSDTESAP-SPSPVEAAKSSEDSSENAASRGNTEPVAELEATTDPAPCA 807
Cdd:PRK11907    19 TASNPKLAQAEEIVTTTPATSTEAEQTTPVESDATEEADnTETPVAATTAAEAPSSSETAETSDPTSEATDTTTSEARTV 98

                           90       100
                   ....*....|....*....|....*....
gi 1958660523  808 SPSSAVpTTKPAESESVEAQVTDSASVET 836
Cdd:PRK11907    99 TPAATE-TSKPVEGQTVDVRILSTTDLHT 126
PHA03169 PHA03169
hypothetical protein; Provisional
 692-901 3.92e-03

hypothetical protein; Provisional


Pssm-ID: 223003 [Multi-domain]  Cd Length: 413  Bit Score: 42.27  E-value: 3.92e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958660523  692 KRRHNLDNLLQQH-KQKVSRAVVASRKPREERDVSQCESVASTVSAQEDEDIEASNEEENPEDSEGAENSSDTESAPSPS 770
Cdd:PHA03169    10 RSRHTLRSSCRGHcKRHGGTREQAGRRRGTAARAAKPAPPAPTTSGPQVRAVAEQGHRQTESDTETAEESRHGEKEERGQ 89

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958660523  771 PVEAAKSSEDSSENAASRGNTEPV----AELEATTDPAPCASPSSAVPTTKPAESESVEaqvtdSASVETAEPMDVDHEE 846
Cdd:PHA03169    90 GGPSGSGSESVGSPTPSPSGSAEElasgLSPENTSGSSPESPASHSPPPSPPSHPGPHE-----PAPPESHNPSPNQQPS 164

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958660523  847 CGAQGSSVLDPPAPTKADSVDPEI-----QVPENTASKGEGDAKDRDLESASEKTEARDE 901
Cdd:PHA03169   165 SFLQPSHEDSPEEPEPPTSEPEPDspgppQSETPTSSPPPQSPPDEPGEPQSPTPQQAPS 224
rne PRK10811
ribonuclease E; Reviewed
 713-879 6.33e-03

ribonuclease E; Reviewed


Pssm-ID: 236766 [Multi-domain]  Cd Length: 1068  Bit Score: 41.95  E-value: 6.33e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958660523  713 VASRKPREERDVSQCESVASTVSAQEDEDIEASNEEENPEDSEGAENSSDTESAPSPSPVEAAKSSEDSSENAASRGNTE 792
Cdd:PRK10811   847 VVRPQDVQVEEQREAEEVQVQPVVAEVPVAAAVEPVVSAPVVEAVAEVVEEPVVVAEPQPEEVVVVETTHPEVIAAPVTE 926

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958660523  793 PVAELEATTDPAPCASPSSAVPTTKPAESESVEAQVTDSASVETAEPMDVDHEECGAQGSSVLDPPAPTKADSVDPEIQV 872
Cdd:PRK10811   927 QPQVITESDVAVAQEVAEHAEPVVEPQDETADIEEAAETAEVVVAEPEVVAQPAAPVVAEVAAEVETVTAVEPEVAPAQV 1006


                   ....*..
gi 1958660523  873 PENTASK 879
Cdd:PRK10811  1007 PEATVEH 1013
AIF-MLS pfam14962
Mitochondria localization Sequence; This family contains a protein found in eukaryotes. ...
 747-867 6.83e-03

Mitochondria localization Sequence; This family contains a protein found in eukaryotes. Proteins in this family are typically between 240 and 613 amino acids in length. The family is found in association with pfam07992. This protein family is an N-terminal domain for the mitochondrial localization sequence for an apoptosis-inducing factor. The protein is also known as Corneal endothelium-specific protein 1 or as Ovary-specific acidic protein. It is thought to be important for membrane function and is expressed in the ovary and corneal endothelium.


Pssm-ID: 464407 [Multi-domain]  Cd Length: 192  Bit Score: 40.20  E-value: 6.83e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958660523  747 EEENPEDSEGAenSSDtesAPSPSPVEAakSSEDSSENaasrgntePVAELEATTDPAPCASPSSAVPTTKPAESESVEA 826
Cdd:pfam14962   95 EKENVAEAEKA--SSE---APEVSVVEA--EVVDAEEI--------PDATAAVIEEASACPGDVEAAPVETTAVGAETGP 159

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|.
gi 1958660523  827 QVTDSASVETAepmdvdheECGAQGSSVLDPPAPTKADSVD 867
Cdd:pfam14962  160 EVTDAATGETT--------EVSAETTPEVTSAAPDEAVAID 192
motB PRK12799
flagellar motor protein MotB; Reviewed
 737-879 6.96e-03

flagellar motor protein MotB; Reviewed


Pssm-ID: 183756 [Multi-domain]  Cd Length: 421  Bit Score: 41.62  E-value: 6.96e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958660523  737 QEDEDIEASNEEE---NPEDSEGAENSSDTESAPSPSPVEAAKSSEDSSENAASRGNTEPVAELEATTDP--APCASPSS 811
Cdd:PRK12799   267 QSQHDIEHENLDNralDIEKATGLKQIDTHGTVPVAAVTPSSAVTQSSAITPSSAAIPSPAVIPSSVTTQsaTTTQASAV 346

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1958660523  812 AVPTTKPAESESVEAQVTDSASVET----AEPMDVDHEECGAQGSSVLDPPAPTKADSVDPEIQVPENTASK 879
Cdd:PRK12799   347 ALSSAGVLPSDVTLPGTVALPAAEPvnmqPQPMSTTETQQSSTGNITSTANGPTTSLPAAPASNIPVSPTSR 418
MDN1 COG5271
Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal ...
 735-937 8.93e-03

Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444083 [Multi-domain]  Cd Length: 1028  Bit Score: 41.54  E-value: 8.93e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958660523  735 SAQEDEDIEASNEEENPED---------SEGAENSSDTEsapspSPVEAAKSSEDSSENAASRGNTEpvaelEATTDPAP 805
Cdd:COG5271    645 SEAADEDADAETEAEASADeseeeaedeSETSSEDAEED-----ADAAAAEASDDEEETEEADEDAE-----TASEEADA 714

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958660523  806 CASPSSAVPTTKPAESESVEAQVTDSASVETAEPMDVDHEECGAQGSSVLDppAPTKADSVDPEIQVPENTASKGEGDAK 885
Cdd:COG5271    715 EEADTEADGTAEEAEEAAEEAESADEEAASLPDEADAEEEAEEAEEAEEDD--ADGLEEALEEEKADAEEAATDEEAEAA 792

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1958660523  886 DRDLESASEKTEARDEDLVVAEQ------MQRPEPQSDNDSSATCSADEDVDGEPERQ 937
Cdd:COG5271    793 AEEKEKVADEDQDTDEDALLDEAeadeeeDLDGEDEETADEALEDIEAGIAEDDEEDD 850
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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