|
Name |
Accession |
Description |
Interval |
E-value |
| DENN |
smart00799 |
Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN; The ... |
1-90 |
1.78e-39 |
|
Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN; The DENN domain is found in a variety of signalling proteins involved in Rab-mediated processes or regulation of MAPKs signalling pathways. The DENN domain is always encircled on both sides by more divergent domains, called uDENN (for upstream DENN) and dDENN (for downstream DENN). The function of the DENN domain remains to date unclear, although it appears to represent a good candidate for a GTP/GDP exchange activity.
:
Pssm-ID: 214823 Cd Length: 183 Bit Score: 144.26 E-value: 1.78e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138289 1 MLHLYASMLYERRILIICSKLSTLTACIHGSAAMLYPMYWQHVYIPVLPPHLLDYCCAPMPYLIGIHLSLMEKVRNMALD 80
Cdd:smart00799 94 ILQLFAALLLERRIIFTSSNLSTLSAVIEALLALLYPFVWQHIYIPILPASLLDVLSAPTPFIIGVHSSYFEEVKELPDE 173
|
90
....*....|
gi 1907138289 81 DVVILNVDTN 90
Cdd:smart00799 174 DVVVVDLDTG 183
|
|
| dDENN |
smart00801 |
Domain always found downstream of DENN domain, found in a variety of signalling proteins; The ... |
122-188 |
1.50e-16 |
|
Domain always found downstream of DENN domain, found in a variety of signalling proteins; The dDENN domain is part of the tripartite DENN domain. It is always found downstream of the DENN domain itself, which is found in a variety of signalling proteins involved in Rab-mediated processes or regulation of MAPKs signalling pathways. The DENN domain is always encircled on both sides by more divergent domains, called uDENN (for upstream DENN) and dDENN (for downstream DENN). The function of the DENN domain remains to date unclear, although it appears to represent a good candidate for a GTP/GDP exchange activity.
:
Pssm-ID: 129037 Cd Length: 69 Bit Score: 74.63 E-value: 1.50e-16
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138289 122 GDGVARAFLKAQAAFFGSYRNALK---IEPEEPITFSEEAFVSHyRSGAMKQFLQNATQLQLFKQFIDGR 188
Cdd:smart00801 1 NDEIREAFLRFFVNLFGGYRNFLRelrKEPGPVITFDKESFLKS-RPSSERPFLSKFLETQMFSQFIEER 69
|
|
| PHA03247 super family |
cl33720 |
large tegument protein UL36; Provisional |
466-792 |
2.67e-13 |
|
large tegument protein UL36; Provisional
The actual alignment was detected with superfamily member PHA03247:
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 74.20 E-value: 2.67e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138289 466 PSKPSITSPEKPSAllGTSPAlPLRPQNQEGILSPSIKEETPIPTPGSITIPRPQGRKTPELGIVPPPPTARPAKLQAAG 545
Cdd:PHA03247 2616 PLPPDTHAPDPPPP--SPSPA-ANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTV 2692
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138289 546 GPLGDFSSEPLQ--MDRERQAALSPALLSGLLPRAVPQG---PTELLQPPSPAPGAAGTGSDALLALLDPLNTAWSGSTI 620
Cdd:PHA03247 2693 GSLTSLADPPPPppTPEPAPHALVSATPLPPGPAAARQAspaLPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPP 2772
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138289 621 PSHPATPSAATPFIPQLSFPPTVTPTPFVQTPLNPfVPSVPVVPPSMPLSSTPARPFGTPPASL--GPAYAPSIL---LS 695
Cdd:PHA03247 2773 AAPAAGPPRRLTRPAVASLSESRESLPSPWDPADP-PAAVLAPAAALPPAASPAGPLPPPTSAQptAPPPPPGPPppsLP 2851
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138289 696 SSGFYAP----HRSQPNLSALSMPNLFGQIPMG-----AHTSPLQPLGPPAVAPSRIRTLPLARSSARAAEAKQglALRP 766
Cdd:PHA03247 2852 LGGSVAPggdvRRRPPSRSPAAKPAAPARPPVRrlarpAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPP--PPQP 2929
|
330 340
....*....|....*....|....*.
gi 1907138289 767 GESPLLPPRPPQSLQPTPQPSVPTQA 792
Cdd:PHA03247 2930 QPPPPPPPRPQPPLAPTTDPAGAGEP 2955
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| DENN |
smart00799 |
Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN; The ... |
1-90 |
1.78e-39 |
|
Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN; The DENN domain is found in a variety of signalling proteins involved in Rab-mediated processes or regulation of MAPKs signalling pathways. The DENN domain is always encircled on both sides by more divergent domains, called uDENN (for upstream DENN) and dDENN (for downstream DENN). The function of the DENN domain remains to date unclear, although it appears to represent a good candidate for a GTP/GDP exchange activity.
Pssm-ID: 214823 Cd Length: 183 Bit Score: 144.26 E-value: 1.78e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138289 1 MLHLYASMLYERRILIICSKLSTLTACIHGSAAMLYPMYWQHVYIPVLPPHLLDYCCAPMPYLIGIHLSLMEKVRNMALD 80
Cdd:smart00799 94 ILQLFAALLLERRIIFTSSNLSTLSAVIEALLALLYPFVWQHIYIPILPASLLDVLSAPTPFIIGVHSSYFEEVKELPDE 173
|
90
....*....|
gi 1907138289 81 DVVILNVDTN 90
Cdd:smart00799 174 DVVVVDLDTG 183
|
|
| DENN |
pfam02141 |
DENN (AEX-3) domain; DENN (after differentially expressed in neoplastic vs normal cells) is a ... |
1-90 |
3.53e-30 |
|
DENN (AEX-3) domain; DENN (after differentially expressed in neoplastic vs normal cells) is a domain which occurs in several proteins involved in Rab- mediated processes or regulation of MAPK signalling pathways.
Pssm-ID: 460461 Cd Length: 186 Bit Score: 117.67 E-value: 3.53e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138289 1 MLHLYASMLYERRILIICSKLSTLTACIHGSAAMLYPMYWQHVYIPVLPPHLLDYCCAPMPYLIGIHLSLMEKVRNmALD 80
Cdd:pfam02141 98 ILQLFEAALLERRIIFLSSDLARLTLVAEAVVALLYPFVWQHIYIPVLPASLLDVLSAPTPFIIGVHSRYFDLLED-PLD 176
|
90
....*....|
gi 1907138289 81 DVVILNVDTN 90
Cdd:pfam02141 177 DVVLVDLDTG 186
|
|
| dDENN |
smart00801 |
Domain always found downstream of DENN domain, found in a variety of signalling proteins; The ... |
122-188 |
1.50e-16 |
|
Domain always found downstream of DENN domain, found in a variety of signalling proteins; The dDENN domain is part of the tripartite DENN domain. It is always found downstream of the DENN domain itself, which is found in a variety of signalling proteins involved in Rab-mediated processes or regulation of MAPKs signalling pathways. The DENN domain is always encircled on both sides by more divergent domains, called uDENN (for upstream DENN) and dDENN (for downstream DENN). The function of the DENN domain remains to date unclear, although it appears to represent a good candidate for a GTP/GDP exchange activity.
Pssm-ID: 129037 Cd Length: 69 Bit Score: 74.63 E-value: 1.50e-16
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138289 122 GDGVARAFLKAQAAFFGSYRNALK---IEPEEPITFSEEAFVSHyRSGAMKQFLQNATQLQLFKQFIDGR 188
Cdd:smart00801 1 NDEIREAFLRFFVNLFGGYRNFLRelrKEPGPVITFDKESFLKS-RPSSERPFLSKFLETQMFSQFIEER 69
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
466-792 |
2.67e-13 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 74.20 E-value: 2.67e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138289 466 PSKPSITSPEKPSAllGTSPAlPLRPQNQEGILSPSIKEETPIPTPGSITIPRPQGRKTPELGIVPPPPTARPAKLQAAG 545
Cdd:PHA03247 2616 PLPPDTHAPDPPPP--SPSPA-ANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTV 2692
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138289 546 GPLGDFSSEPLQ--MDRERQAALSPALLSGLLPRAVPQG---PTELLQPPSPAPGAAGTGSDALLALLDPLNTAWSGSTI 620
Cdd:PHA03247 2693 GSLTSLADPPPPppTPEPAPHALVSATPLPPGPAAARQAspaLPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPP 2772
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138289 621 PSHPATPSAATPFIPQLSFPPTVTPTPFVQTPLNPfVPSVPVVPPSMPLSSTPARPFGTPPASL--GPAYAPSIL---LS 695
Cdd:PHA03247 2773 AAPAAGPPRRLTRPAVASLSESRESLPSPWDPADP-PAAVLAPAAALPPAASPAGPLPPPTSAQptAPPPPPGPPppsLP 2851
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138289 696 SSGFYAP----HRSQPNLSALSMPNLFGQIPMG-----AHTSPLQPLGPPAVAPSRIRTLPLARSSARAAEAKQglALRP 766
Cdd:PHA03247 2852 LGGSVAPggdvRRRPPSRSPAAKPAAPARPPVRrlarpAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPP--PPQP 2929
|
330 340
....*....|....*....|....*.
gi 1907138289 767 GESPLLPPRPPQSLQPTPQPSVPTQA 792
Cdd:PHA03247 2930 QPPPPPPPRPQPPLAPTTDPAGAGEP 2955
|
|
| dDENN |
pfam03455 |
dDENN domain; This region is always found associated with pfam02141. It is predicted to form a ... |
154-205 |
3.11e-07 |
|
dDENN domain; This region is always found associated with pfam02141. It is predicted to form a globular domain. Although not statistically supported it has been suggested that this domain may be similar to members of the Rho/Rac/Cdc42 GEF family. This N-terminal region of DENN folds into a longin module, consisting of a central antiparallel beta-sheet layered between helix H1 and helices H2 and H3 (strands S1-S5). Rab35 interacts with dDENN via residues in helix 1 and in the loop S3-S4.
Pssm-ID: 460925 Cd Length: 48 Bit Score: 47.57 E-value: 3.11e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 1907138289 154 FSEEAFVSHyRSGAMKQFLQNATQLQLFKQFIDGRLDLLNsgeGFSDVFEEE 205
Cdd:pfam03455 1 FDKEAFLKS-LPSDSRPFLSQFLETQMFNEFIEERLESSD---PSIDLFDEE 48
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
467-796 |
8.18e-05 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 46.30 E-value: 8.18e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138289 467 SKPSITSPEK------PSALLGTSPALPLRPQNQEGILSPSikeETPIPTPGSITIPRPQGRKTPELGIVPPPPTARPAK 540
Cdd:pfam03154 144 TSPSIPSPQDnesdsdSSAQQQILQTQPPVLQAQSGAASPP---SPPPPGTTQAATAGPTPSAPSVPPQGSPATSQPPNQ 220
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138289 541 LQAAGGPLGDFSSEPlQMDRERQAALSPALLSGLLPRAVPQGPTELLQPPS------PAPGAAGTGsdallalldplnta 614
Cdd:pfam03154 221 TQSTAAPHTLIQQTP-TLHPQRLPSPHPPLQPMTQPPPPSQVSPQPLPQPSlhgqmpPMPHSLQTG-------------- 285
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138289 615 wsgstiPSHPATPSAATPF-IPQLSFPPTVTPTPFVQTPLNPFVPSVPVVPPSMPLSSTPARPFGTPPASLGPAYA---- 689
Cdd:pfam03154 286 ------PSHMQHPVPPQPFpLTPQSSQSQVPPGPSPAAPGQSQQRIHTPPSQSQLQSQQPPREQPLPPAPLSMPHIkppp 359
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138289 690 ----PSILLSSSGFYAPHRSQPnlSALSMPNLFGQIPMGAHTSPLQPLGPPAVAPSRIRTLPLARSSARAAEAKQGLAlr 765
Cdd:pfam03154 360 ttpiPQLPNPQSHKHPPHLSGP--SPFQMNSNLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQQLPPPPAQPPVLT-- 435
|
330 340 350
....*....|....*....|....*....|.
gi 1907138289 766 pgESPLLPprPPQSLQPTPQPSVPTQARDPF 796
Cdd:pfam03154 436 --QSQSLP--PPAASHPPTSGLHQVPSQSPF 462
|
|
| PPE |
COG5651 |
PPE-repeat protein [Function unknown]; |
532-742 |
9.85e-05 |
|
PPE-repeat protein [Function unknown];
Pssm-ID: 444372 [Multi-domain] Cd Length: 385 Bit Score: 45.65 E-value: 9.85e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138289 532 PPPTARPAKLQAAGGPLGDFSSEPLQMD---RERQAALSPALLSGLLPRAVPQGPTELLQPPSPApGAAGTGSDALLALL 608
Cdd:COG5651 165 TPFTQPPPTITNPGGLLGAQNAGSGNTSsnpGFANLGLTGLNQVGIGGLNSGSGPIGLNSGPGNT-GFAGTGAAAGAAAA 243
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138289 609 DPLNTAWSGSTIPSHPATPSAATPFIPQLSFPPTVTPTPFVQTPLNPFVPSVPVVPPSMP----LSSTPARPFGTPPASL 684
Cdd:COG5651 244 AAAAAAAAGAGASAALASLAATLLNASSLGLAATAASSAATNLGLAGSPLGLAGGGAGAAaatgLGLGAGGAAGAAGATG 323
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 1907138289 685 GPAYAPSILLSSSGFYAPHRSQPNLSALSMPNLFGQIPMGAHTSPLQPLGPPAVAPSR 742
Cdd:COG5651 324 AGAALGAGAAAAAAGAAAGAGAAAAAAAGGAGGGGGGALGAGGGGGSAGAAAGAASGG 381
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| DENN |
smart00799 |
Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN; The ... |
1-90 |
1.78e-39 |
|
Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN; The DENN domain is found in a variety of signalling proteins involved in Rab-mediated processes or regulation of MAPKs signalling pathways. The DENN domain is always encircled on both sides by more divergent domains, called uDENN (for upstream DENN) and dDENN (for downstream DENN). The function of the DENN domain remains to date unclear, although it appears to represent a good candidate for a GTP/GDP exchange activity.
Pssm-ID: 214823 Cd Length: 183 Bit Score: 144.26 E-value: 1.78e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138289 1 MLHLYASMLYERRILIICSKLSTLTACIHGSAAMLYPMYWQHVYIPVLPPHLLDYCCAPMPYLIGIHLSLMEKVRNMALD 80
Cdd:smart00799 94 ILQLFAALLLERRIIFTSSNLSTLSAVIEALLALLYPFVWQHIYIPILPASLLDVLSAPTPFIIGVHSSYFEEVKELPDE 173
|
90
....*....|
gi 1907138289 81 DVVILNVDTN 90
Cdd:smart00799 174 DVVVVDLDTG 183
|
|
| DENN |
pfam02141 |
DENN (AEX-3) domain; DENN (after differentially expressed in neoplastic vs normal cells) is a ... |
1-90 |
3.53e-30 |
|
DENN (AEX-3) domain; DENN (after differentially expressed in neoplastic vs normal cells) is a domain which occurs in several proteins involved in Rab- mediated processes or regulation of MAPK signalling pathways.
Pssm-ID: 460461 Cd Length: 186 Bit Score: 117.67 E-value: 3.53e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138289 1 MLHLYASMLYERRILIICSKLSTLTACIHGSAAMLYPMYWQHVYIPVLPPHLLDYCCAPMPYLIGIHLSLMEKVRNmALD 80
Cdd:pfam02141 98 ILQLFEAALLERRIIFLSSDLARLTLVAEAVVALLYPFVWQHIYIPVLPASLLDVLSAPTPFIIGVHSRYFDLLED-PLD 176
|
90
....*....|
gi 1907138289 81 DVVILNVDTN 90
Cdd:pfam02141 177 DVVLVDLDTG 186
|
|
| dDENN |
smart00801 |
Domain always found downstream of DENN domain, found in a variety of signalling proteins; The ... |
122-188 |
1.50e-16 |
|
Domain always found downstream of DENN domain, found in a variety of signalling proteins; The dDENN domain is part of the tripartite DENN domain. It is always found downstream of the DENN domain itself, which is found in a variety of signalling proteins involved in Rab-mediated processes or regulation of MAPKs signalling pathways. The DENN domain is always encircled on both sides by more divergent domains, called uDENN (for upstream DENN) and dDENN (for downstream DENN). The function of the DENN domain remains to date unclear, although it appears to represent a good candidate for a GTP/GDP exchange activity.
Pssm-ID: 129037 Cd Length: 69 Bit Score: 74.63 E-value: 1.50e-16
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138289 122 GDGVARAFLKAQAAFFGSYRNALK---IEPEEPITFSEEAFVSHyRSGAMKQFLQNATQLQLFKQFIDGR 188
Cdd:smart00801 1 NDEIREAFLRFFVNLFGGYRNFLRelrKEPGPVITFDKESFLKS-RPSSERPFLSKFLETQMFSQFIEER 69
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
466-792 |
2.67e-13 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 74.20 E-value: 2.67e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138289 466 PSKPSITSPEKPSAllGTSPAlPLRPQNQEGILSPSIKEETPIPTPGSITIPRPQGRKTPELGIVPPPPTARPAKLQAAG 545
Cdd:PHA03247 2616 PLPPDTHAPDPPPP--SPSPA-ANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTV 2692
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138289 546 GPLGDFSSEPLQ--MDRERQAALSPALLSGLLPRAVPQG---PTELLQPPSPAPGAAGTGSDALLALLDPLNTAWSGSTI 620
Cdd:PHA03247 2693 GSLTSLADPPPPppTPEPAPHALVSATPLPPGPAAARQAspaLPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPP 2772
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138289 621 PSHPATPSAATPFIPQLSFPPTVTPTPFVQTPLNPfVPSVPVVPPSMPLSSTPARPFGTPPASL--GPAYAPSIL---LS 695
Cdd:PHA03247 2773 AAPAAGPPRRLTRPAVASLSESRESLPSPWDPADP-PAAVLAPAAALPPAASPAGPLPPPTSAQptAPPPPPGPPppsLP 2851
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138289 696 SSGFYAP----HRSQPNLSALSMPNLFGQIPMG-----AHTSPLQPLGPPAVAPSRIRTLPLARSSARAAEAKQglALRP 766
Cdd:PHA03247 2852 LGGSVAPggdvRRRPPSRSPAAKPAAPARPPVRrlarpAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPP--PPQP 2929
|
330 340
....*....|....*....|....*.
gi 1907138289 767 GESPLLPPRPPQSLQPTPQPSVPTQA 792
Cdd:PHA03247 2930 QPPPPPPPRPQPPLAPTTDPAGAGEP 2955
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
466-791 |
5.99e-12 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 69.97 E-value: 5.99e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138289 466 PSKPSITSPE-KPSAllgtsPALPLRPQnqegilspsikeeTPIPTPGSITIPRPQGRKTPELGIVPPPPTARPAKLQAA 544
Cdd:PHA03247 2577 PSEPAVTSRArRPDA-----PPQSARPR-------------APVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEP 2638
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138289 545 GGPLGDFSSEPLQMD------RERQAALSPALLSGLLPRAVPQGPTELLQPPSPAPGAAGTGSDALLALLDPLNTAW-SG 617
Cdd:PHA03247 2639 DPHPPPTVPPPERPRddpapgRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSLTSLADPPPPPPTPEPAPHALvSA 2718
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138289 618 STIPSHPATPSAATPFIPQLSFPPTVTPTPfvQTPLNPFVPSVPVVPPSMPLSSTPARPFGTPPASLGPAYAPSILLSSS 697
Cdd:PHA03247 2719 TPLPPGPAAARQASPALPAAPAPPAVPAGP--ATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRE 2796
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138289 698 GFYAPHRSQPNLSALSMPNLFGQI------PMGAHTSPLQPLGPPAVAPSRIRTLPLARSSARAAEAKQGLALRPGESPL 771
Cdd:PHA03247 2797 SLPSPWDPADPPAAVLAPAAALPPaaspagPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPGGDVRRRPPSRSPAAKPA 2876
|
330 340
....*....|....*....|
gi 1907138289 772 LPPRPPQSLQPTPQPSVPTQ 791
Cdd:PHA03247 2877 APARPPVRRLARPAVSRSTE 2896
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
314-793 |
8.14e-11 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 66.12 E-value: 8.14e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138289 314 VRPPRPhvVRRPkSNITVEGRRTSVSSPEQPQPYRTlkesdsaEGDETESPeqlvREPWGPTPAPPDRAASidlleDVFS 393
Cdd:PHA03247 2568 VPPPRP--APRP-SEPAVTSRARRPDAPPQSARPRA-------PVDDRGDP----RGPAPPSPLPPDTHAP-----DPPP 2628
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138289 394 SLDVEAPLQPLGQAKSLEDLRAPKDLREQPGSFDYQRlDLCRSERGLSMAAALKLAHPYTKLWSLGQ-DDMAIPSKPSIT 472
Cdd:PHA03247 2629 PSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPR-RARRLGRAAQASSPPQRPRRRAARPTVGSlTSLADPPPPPPT 2707
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138289 473 SPEKPSAllgTSPALPLRPQNQEGILSPSIKEETPIPTPGSITIPRPQGRKTPElgivPPPPTARPAKLQAAGGPLGdfs 552
Cdd:PHA03247 2708 PEPAPHA---LVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPA----RPPTTAGPPAPAPPAAPAA--- 2777
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138289 553 SEPLQMDRERQAALSPALLSGLLPRAvPQGPTELLQPPSPAPGAAGTGSDALLALLDPLNTAWSGSTIPSHPATP--SAA 630
Cdd:PHA03247 2778 GPPRRLTRPAVASLSESRESLPSPWD-PADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPlgGSV 2856
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138289 631 TPFIPQLSFPPTVTPTPFVQTPLNPfvpsvPVVPPSMPLSSTPARPFGTPPASLGPAYAPSIllsssgfYAPHRSQPNLS 710
Cdd:PHA03247 2857 APGGDVRRRPPSRSPAAKPAAPARP-----PVRRLARPAVSRSTESFALPPDQPERPPQPQA-------PPPPQPQPQPP 2924
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138289 711 ALSMPNLFGQIPmGAHTSPLQPLGPPAVAPSRIRTLPlarssaraaeAKQGLALRPGESPLLPPRPPQSLQPTPQPSVPT 790
Cdd:PHA03247 2925 PPPQPQPPPPPP-PRPQPPLAPTTDPAGAGEPSGAVP----------QPWLGALVPGRVAVPRFRVPQPAPSREAPASST 2993
|
...
gi 1907138289 791 QAR 793
Cdd:PHA03247 2994 PPL 2996
|
|
| dDENN |
pfam03455 |
dDENN domain; This region is always found associated with pfam02141. It is predicted to form a ... |
154-205 |
3.11e-07 |
|
dDENN domain; This region is always found associated with pfam02141. It is predicted to form a globular domain. Although not statistically supported it has been suggested that this domain may be similar to members of the Rho/Rac/Cdc42 GEF family. This N-terminal region of DENN folds into a longin module, consisting of a central antiparallel beta-sheet layered between helix H1 and helices H2 and H3 (strands S1-S5). Rab35 interacts with dDENN via residues in helix 1 and in the loop S3-S4.
Pssm-ID: 460925 Cd Length: 48 Bit Score: 47.57 E-value: 3.11e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 1907138289 154 FSEEAFVSHyRSGAMKQFLQNATQLQLFKQFIDGRLDLLNsgeGFSDVFEEE 205
Cdd:pfam03455 1 FDKEAFLKS-LPSDSRPFLSQFLETQMFNEFIEERLESSD---PSIDLFDEE 48
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
278-647 |
3.43e-06 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 51.09 E-value: 3.43e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138289 278 SSAEDPLPKTMPSPQAETQDPRLREDRRPITVHFGQVRPPRPHV------VRRPKsNITVEGRRTSVSSPEQPQPYRTLK 351
Cdd:PHA03247 2611 PAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDdpapgrVSRPR-RARRLGRAAQASSPPQRPRRRAAR 2689
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138289 352 E-----SDSAEGDETESPEQLVREPWGP-TPAPP----DRAASIDLLEDVFSSLDVEAPLQPLGQAKsledlRAPKDLRE 421
Cdd:PHA03247 2690 PtvgslTSLADPPPPPPTPEPAPHALVSaTPLPPgpaaARQASPALPAAPAPPAVPAGPATPGGPAR-----PARPPTTA 2764
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138289 422 QPGSFDYQRLDLCRSERGLSMAAALKLAHPYTKLWS----LGQDDMAIPSKPSITSPEKPSALLGTSP-ALPLRPQNQEG 496
Cdd:PHA03247 2765 GPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSpwdpADPPAAVLAPAAALPPAASPAGPLPPPTsAQPTAPPPPPG 2844
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138289 497 ILSPSIKEETPIpTPGSITIPRPQGRKTPELGIVPPPPTARPAKLQAAGGPLGDFSSEPLQMDRERQAALSPALLSGLLP 576
Cdd:PHA03247 2845 PPPPSLPLGGSV-APGGDVRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQP 2923
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1907138289 577 RAVPQGPTELLQPPSP-APGAAGTGSDALLALLDPLNTAWSGSTIPSHPATPSAATPfIPQLSFPPTVTPTP 647
Cdd:PHA03247 2924 PPPPQPQPPPPPPPRPqPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVP-QPAPSREAPASSTP 2994
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
487-733 |
2.87e-05 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 47.56 E-value: 2.87e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138289 487 LPLRPQNQEGILSPsikeetpiPTPGSITIPRPQGRKTPELGIVPPPPTARPAKLQAAGgplgdfSSEPLQMDRERQAAL 566
Cdd:PRK12323 361 LAFRPGQSGGGAGP--------ATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPA------AAAAARAVAAAPARR 426
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138289 567 SPAL--LSGLLPRAVPQGPTELLQPPSPAPGAAGTGSDALLALLDPLNTAWSGSTIPSHPATPSAATPFIPQLSFPPTVT 644
Cdd:PRK12323 427 SPAPeaLAAARQASARGPGGAPAPAPAPAAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDDPPPWEELPPEF 506
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138289 645 PTPFVQtPLNPFVPSVPVVPPSMPLSSTPARPFGTPPASLGPAYAPSILLSSSGFYAPHRsqPNLSALSMPNLF-GQIPM 723
Cdd:PRK12323 507 ASPAPA-QPDAAPAGWVAESIPDPATADPDDAFETLAPAPAAAPAPRAAAATEPVVAPRP--PRASASGLPDMFdGDWPA 583
|
250
....*....|
gi 1907138289 724 GAHTSPLQPL 733
Cdd:PRK12323 584 LAARLPVRGL 593
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
457-800 |
3.42e-05 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 48.01 E-value: 3.42e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138289 457 SLGQDDMAIPSKPSITSPekpSALLGTSPALPLRPQNQEGI--LSPSIKEETPIPTPGSITIPRPqgrKTPELGIVPPPP 534
Cdd:PHA03247 2500 GGGPPDPDAPPAPSRLAP---AILPDEPVGEPVHPRMLTWIrgLEELASDDAGDPPPPLPPAAPP---AAPDRSVPPPRP 2573
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138289 535 TARPAklQAAGGPLGDFSSEPLQMDRERQAALSPALLSGLLPRAVPQGPTELLQPPSPAPGAAGT----GSDALLALLDP 610
Cdd:PHA03247 2574 APRPS--EPAVTSRARRPDAPPQSARPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANepdpHPPPTVPPPER 2651
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138289 611 LNTAWSGSTI--------PSHPATPSAATPFIPQLSFPPTVTPTPFVQTPLNPFVPSVPVVPPSMPLSSTPARPFGTPPA 682
Cdd:PHA03247 2652 PRDDPAPGRVsrprrarrLGRAAQASSPPQRPRRRAARPTVGSLTSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQA 2731
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138289 683 SLGPAYAPSILLSSSGFYAP--HRSQPNLSALSMPNLfGQIPMGAHTSPLQPLGPPAVAPSRIRTLPLARSSARAAEAKQ 760
Cdd:PHA03247 2732 SPALPAAPAPPAVPAGPATPggPARPARPPTTAGPPA-PAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAA 2810
|
330 340 350 360
....*....|....*....|....*....|....*....|
gi 1907138289 761 GLALRPGESPLLPPRPPQSLQPTPQPSVPTQARDPFEDLL 800
Cdd:PHA03247 2811 VLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSL 2850
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
467-796 |
8.18e-05 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 46.30 E-value: 8.18e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138289 467 SKPSITSPEK------PSALLGTSPALPLRPQNQEGILSPSikeETPIPTPGSITIPRPQGRKTPELGIVPPPPTARPAK 540
Cdd:pfam03154 144 TSPSIPSPQDnesdsdSSAQQQILQTQPPVLQAQSGAASPP---SPPPPGTTQAATAGPTPSAPSVPPQGSPATSQPPNQ 220
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138289 541 LQAAGGPLGDFSSEPlQMDRERQAALSPALLSGLLPRAVPQGPTELLQPPS------PAPGAAGTGsdallalldplnta 614
Cdd:pfam03154 221 TQSTAAPHTLIQQTP-TLHPQRLPSPHPPLQPMTQPPPPSQVSPQPLPQPSlhgqmpPMPHSLQTG-------------- 285
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138289 615 wsgstiPSHPATPSAATPF-IPQLSFPPTVTPTPFVQTPLNPFVPSVPVVPPSMPLSSTPARPFGTPPASLGPAYA---- 689
Cdd:pfam03154 286 ------PSHMQHPVPPQPFpLTPQSSQSQVPPGPSPAAPGQSQQRIHTPPSQSQLQSQQPPREQPLPPAPLSMPHIkppp 359
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138289 690 ----PSILLSSSGFYAPHRSQPnlSALSMPNLFGQIPMGAHTSPLQPLGPPAVAPSRIRTLPLARSSARAAEAKQGLAlr 765
Cdd:pfam03154 360 ttpiPQLPNPQSHKHPPHLSGP--SPFQMNSNLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQQLPPPPAQPPVLT-- 435
|
330 340 350
....*....|....*....|....*....|.
gi 1907138289 766 pgESPLLPprPPQSLQPTPQPSVPTQARDPF 796
Cdd:pfam03154 436 --QSQSLP--PPAASHPPTSGLHQVPSQSPF 462
|
|
| PPE |
COG5651 |
PPE-repeat protein [Function unknown]; |
532-742 |
9.85e-05 |
|
PPE-repeat protein [Function unknown];
Pssm-ID: 444372 [Multi-domain] Cd Length: 385 Bit Score: 45.65 E-value: 9.85e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138289 532 PPPTARPAKLQAAGGPLGDFSSEPLQMD---RERQAALSPALLSGLLPRAVPQGPTELLQPPSPApGAAGTGSDALLALL 608
Cdd:COG5651 165 TPFTQPPPTITNPGGLLGAQNAGSGNTSsnpGFANLGLTGLNQVGIGGLNSGSGPIGLNSGPGNT-GFAGTGAAAGAAAA 243
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138289 609 DPLNTAWSGSTIPSHPATPSAATPFIPQLSFPPTVTPTPFVQTPLNPFVPSVPVVPPSMP----LSSTPARPFGTPPASL 684
Cdd:COG5651 244 AAAAAAAAGAGASAALASLAATLLNASSLGLAATAASSAATNLGLAGSPLGLAGGGAGAAaatgLGLGAGGAAGAAGATG 323
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 1907138289 685 GPAYAPSILLSSSGFYAPHRSQPNLSALSMPNLFGQIPMGAHTSPLQPLGPPAVAPSR 742
Cdd:COG5651 324 AGAALGAGAAAAAAGAAAGAGAAAAAAAGGAGGGGGGALGAGGGGGSAGAAAGAASGG 381
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
465-788 |
1.40e-04 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 45.53 E-value: 1.40e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138289 465 IPSKPSITSPEKPSALLGTSPALPLRPQNQEGILS-PSIKEETPIPTPGSITIPRPQGRKTPelgiVPPPPTARPAKLQA 543
Cdd:pfam03154 231 IQQTPTLHPQRLPSPHPPLQPMTQPPPPSQVSPQPlPQPSLHGQMPPMPHSLQTGPSHMQHP----VPPQPFPLTPQSSQ 306
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138289 544 AGGPLGDFSSEPLQM-DRERQAALSPALLSGLLPRAVPQGPTELLQPPSPAPGAAGTGSDALLALLdplntawsgstipS 622
Cdd:pfam03154 307 SQVPPGPSPAAPGQSqQRIHTPPSQSQLQSQQPPREQPLPPAPLSMPHIKPPPTTPIPQLPNPQSH-------------K 373
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138289 623 HPATPSAATPFIPQLSFPPTVTPTPFVQTPLNPFVPSVPVVPPSMP----LSSTPARPFG-------TPPASLGPAYAPS 691
Cdd:pfam03154 374 HPPHLSGPSPFQMNSNLPPPPALKPLSSLSTHHPPSAHPPPLQLMPqsqqLPPPPAQPPVltqsqslPPPAASHPPTSGL 453
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138289 692 ILLSSSGFYAPHRSQPNLSALSMPNLFGQIPMGAHTSPLQPlgPPAVAPSRIRTLPLARSSARAAEAKQGLALRPGESPL 771
Cdd:pfam03154 454 HQVPSQSPFPQHPFVPGGPPPITPPSGPPTSTSSAMPGIQP--PSSASVSSSGPVPAAVSCPLPPVQIKEEALDEAEEPE 531
|
330
....*....|....*..
gi 1907138289 772 LPPRPPQSlqPTPQPSV 788
Cdd:pfam03154 532 SPPPPPRS--PSPEPTV 546
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
463-807 |
2.12e-04 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 45.16 E-value: 2.12e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138289 463 MAIPSKPSITSPEKPSALLGTSPALPLRPQNQEGILSPSIKEETPIPTPGSITIPRPQGRKTPELGIVPPPPTARPAKLQ 542
Cdd:PHA03307 60 AACDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTLAPASPAREGSPTPPGPSSPDPPPPTPPPASPPPSPAPDLSEMLR 139
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138289 543 AAG--GPLGDFSSEPLQMDRERQAA-----LSPALLSGLLPRAVPQGPTELLQPPSPAPGAAGTGSDALLALLDPLNTAW 615
Cdd:PHA03307 140 PVGspGPPPAASPPAAGASPAAVASdaassRQAALPLSSPEETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASS 219
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138289 616 SGSTIPSHPATPSAATPFIPQLSFPPTVTPTPFVQTPL---NPFVPSVPVVPPSMPLSSTPARPFGTPPASLGPAYAPSI 692
Cdd:PHA03307 220 PAPAPGRSAADDAGASSSDSSSSESSGCGWGPENECPLprpAPITLPTRIWEASGWNGPSSRPGPASSSSSPRERSPSPS 299
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138289 693 LLSSSGFYAPHRSQPNLSALSMPNLFGQIPMGAHTSPLQPLGPPAVAPSRIRTLPlarssaraaeakqglalrPGESPLL 772
Cdd:PHA03307 300 PSSPGSGPAPSSPRASSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPSRSPSPS------------------RPPPPAD 361
|
330 340 350
....*....|....*....|....*....|....*
gi 1907138289 773 PPRPPQSlqPTPQPSVPTQARDPFEDLLRKTKQDV 807
Cdd:PHA03307 362 PSSPRKR--PRPSRAPSSPAASAGRPTRRRARAAV 394
|
|
| PLN03209 |
PLN03209 |
translocon at the inner envelope of chloroplast subunit 62; Provisional |
465-735 |
8.55e-04 |
|
translocon at the inner envelope of chloroplast subunit 62; Provisional
Pssm-ID: 178748 [Multi-domain] Cd Length: 576 Bit Score: 42.99 E-value: 8.55e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138289 465 IPSKPsiTSPEKPSALLGTSPAlPLRPQNQEGILSPSIKEetpiPTPGSITIPRPQGRKTPELGIVPPpptARPAKLQAA 544
Cdd:PLN03209 323 IPSQR--VPPKESDAADGPKPV-PTKPVTPEAPSPPIEEE----PPQPKAVVPRPLSPYTAYEDLKPP---TSPIPTPPS 392
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138289 545 GGPLGDFSSEPLQMDRERQAALSPALLSGLLPRAVPQGPTELLQPPSPApgaagtgsdallalldplnTAWSGSTIPSHP 624
Cdd:PLN03209 393 SSPASSKSVDAVAKPAEPDVVPSPGSASNVPEVEPAQVEAKKTRPLSPY-------------------ARYEDLKPPTSP 453
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138289 625 aTPSAATPFIPQLSFPPTVTPTPFVQTPLNPFVPSVPVVPPSMPLSSTPARPFGTPPASLGPAyapsillSSSGFYAPHR 704
Cdd:PLN03209 454 -SPTAPTGVSPSVSSTSSVPAVPDTAPATAATDAAAPPPANMRPLSPYAVYDDLKPPTSPSPA-------APVGKVAPSS 525
|
250 260 270
....*....|....*....|....*....|..
gi 1907138289 705 SQPNLSALSMPNLFGQIPMGAHTSPLQ-PLGP 735
Cdd:PLN03209 526 TNEVVKVGNSAPPTALADEQHHAQPKPrPLSP 557
|
|
| |
