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Conserved domains on  [gi|1907179509|ref|XP_036008813|]
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CCR4-NOT transcription complex subunit 3 isoform X2 [Mus musculus]

Protein Classification

CNOT2/3/5 family protein( domain architecture ID 13694845)

CNOT2/3/5 family protein is a component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Not3 pfam04065
Not1 N-terminal domain, CCR4-Not complex component;
211-408 3.00e-111

Not1 N-terminal domain, CCR4-Not complex component;


:

Pssm-ID: 461155 [Multi-domain]  Cd Length: 228  Bit Score: 341.45  E-value: 3.00e-111
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179509 211 LHNAANANQKEKYEADLKKEIKKLQRLRDQIKTWVASNEIKDKRQLIENRKLIETQMERFKVVERETKTKAYSKEGLGLA 290
Cdd:pfam04065  30 LESATNSSQKEKLEADLKKEIKKLQRLRDQIKTWLSSNDIKDKKKLLENRKLIEEAMERFKAVEKESKTKAFSKEGLSLA 109

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179509 291 Q--KVDPAQKEKEEVGQWLTNTIDTLNMQVDQFESEVESLSVQTRkKKGDKDKQDRIEGLKRHIEKHRYHVRMLETILRM 368
Cdd:pfam04065 110 AasKLDPKEKEKAEARDWLSDSIDELNRQIEALEAEIESLQAQKK-KKKKDSEKARLEELEKLIERHKFHIEKLELILRL 188

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 1907179509 369 LDNDSILVDAIRKIKDDVEYYVDSSQDPDFEENEFLYDDL 408
Cdd:pfam04065 189 LENGELDPEQVDDIKEDIEYYVESNQDPDFVEDEDIYDDL 228
NOT2_3_5 pfam04153
NOT2 / NOT3 / NOT5 family; NOT1, NOT2, NOT3, NOT4 and NOT5 form a nuclear complex that ...
 797-922 2.91e-56

NOT2 / NOT3 / NOT5 family; NOT1, NOT2, NOT3, NOT4 and NOT5 form a nuclear complex that negatively regulates the basal and activated transcription of many genes. This family includes NOT2, NOT3 and NOT5.


:

Pssm-ID: 461199  Cd Length: 121  Bit Score: 189.73  E-value: 2.91e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179509 797 AAWHHMPHPSDSERIRQYLPRNPCPTPpyhhQMPPPHSDTVEFYQRLSTETLFFIFYYLEGTKAQYLAAKALKKQSWRFH 876
Cdd:pfam04153   1 YSTFNSPWPLDAERPYEPDFRNPACYP----QEPLPRLESPEKFSKFDDETLFYIFYSMPGDYAQYLAAKELKKRSWRYH 76

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 1907179509 877 TKYMMWFQRHEEPKTITDEFEQGTYIYFDYeKWGQRKKEGFTFEYR 922
Cdd:pfam04153  77 KKLRTWFTRDEEPKVITNEYERGTYIYFDY-TWEQRRKKDFTLDYE 121
Herpes_BLLF1 super family cl37540
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 476-743 1.15e-04

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


The actual alignment was detected with superfamily member pfam05109:

Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 46.06  E-value: 1.15e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179509 476 SQSPAKNGSKPVHSNQHPQSPAVPPTYPSGPPPTTSALSSTPgnNGASTPAAPTSALGPKASPAPSHNSGTPapyAQAVA 555
Cdd:pfam05109 491 SPSPRDNGTESKAPDMTSPTSAVTTPTPNATSPTPAVTTPTP--NATSPTLGKTSPTSAVTTPTPNATSPTP---AVTTP 565

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179509 556 PPNASGPSNAQPRPPSAqpSGGSGGGSGGSSSNSNSGTGGGAGKQNGATSYSSVVADSPAEVTLSSS------GGSSASS 629
Cdd:pfam05109 566 TPNATIPTLGKTSPTSA--VTTPTPNATSPTVGETSPQANTTNHTLGGTSSTPVVTSPPKNATSAVTtgqhniTSSSTSS 643

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179509 630 QALGPTSGPHNPAPSTSKESSTAAPsgagnvASGSGNNSGGPSLLVPLPVNPPSSPTPSFSEAKAAGTL--LNGPPQFST 707
Cdd:pfam05109 644 MSLRPSSISETLSPSTSDNSTSHMP------LLTSAHPTGGENITQVTPASTSTHHVSTSSPAPRPGTTsqASGPGNSST 717

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|
gi 1907179509 708 TPEikaPEPLSSLKSMAERAAIS----SGIEDPVPTLHLT 743
Cdd:pfam05109 718 STK---PGEVNVTKGTPPKNATSpqapSGQKTAVPTVTST 754
 
Name Accession Description Interval E-value
Not3 pfam04065
Not1 N-terminal domain, CCR4-Not complex component;
211-408 3.00e-111

Not1 N-terminal domain, CCR4-Not complex component;


Pssm-ID: 461155 [Multi-domain]  Cd Length: 228  Bit Score: 341.45  E-value: 3.00e-111
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179509 211 LHNAANANQKEKYEADLKKEIKKLQRLRDQIKTWVASNEIKDKRQLIENRKLIETQMERFKVVERETKTKAYSKEGLGLA 290
Cdd:pfam04065  30 LESATNSSQKEKLEADLKKEIKKLQRLRDQIKTWLSSNDIKDKKKLLENRKLIEEAMERFKAVEKESKTKAFSKEGLSLA 109

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179509 291 Q--KVDPAQKEKEEVGQWLTNTIDTLNMQVDQFESEVESLSVQTRkKKGDKDKQDRIEGLKRHIEKHRYHVRMLETILRM 368
Cdd:pfam04065 110 AasKLDPKEKEKAEARDWLSDSIDELNRQIEALEAEIESLQAQKK-KKKKDSEKARLEELEKLIERHKFHIEKLELILRL 188

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 1907179509 369 LDNDSILVDAIRKIKDDVEYYVDSSQDPDFEENEFLYDDL 408
Cdd:pfam04065 189 LENGELDPEQVDDIKEDIEYYVESNQDPDFVEDEDIYDDL 228
NOT2_3_5 pfam04153
NOT2 / NOT3 / NOT5 family; NOT1, NOT2, NOT3, NOT4 and NOT5 form a nuclear complex that ...
 797-922 2.91e-56

NOT2 / NOT3 / NOT5 family; NOT1, NOT2, NOT3, NOT4 and NOT5 form a nuclear complex that negatively regulates the basal and activated transcription of many genes. This family includes NOT2, NOT3 and NOT5.


Pssm-ID: 461199  Cd Length: 121  Bit Score: 189.73  E-value: 2.91e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179509 797 AAWHHMPHPSDSERIRQYLPRNPCPTPpyhhQMPPPHSDTVEFYQRLSTETLFFIFYYLEGTKAQYLAAKALKKQSWRFH 876
Cdd:pfam04153   1 YSTFNSPWPLDAERPYEPDFRNPACYP----QEPLPRLESPEKFSKFDDETLFYIFYSMPGDYAQYLAAKELKKRSWRYH 76

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 1907179509 877 TKYMMWFQRHEEPKTITDEFEQGTYIYFDYeKWGQRKKEGFTFEYR 922
Cdd:pfam04153  77 KKLRTWFTRDEEPKVITNEYERGTYIYFDY-TWEQRRKKDFTLDYE 121
CDC36 COG5601
General negative regulator of transcription subunit [Transcription];
822-925 4.11e-14

General negative regulator of transcription subunit [Transcription];


Pssm-ID: 227888  Cd Length: 172  Bit Score: 71.16  E-value: 4.11e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179509 822 TPPYHHQMPPPHSDTVEFYQR----LSTETLFFIFYYLEGTKAQYLAAKALKKQSWRFHTKYMMW--FQRHEEPKTITDE 895
Cdd:COG5601    64 LPNCYPNAPNPPIFKVNIEDMkmdnFHDETLFYIFYSFPNDVLQEKAYDELLKRNWRFHKMLKCWltFNPGMSPATADHV 143

                          90       100       110
                  ....*....|....*....|....*....|
gi 1907179509 896 FEQGTYIYFDYEKWGQRKKEgFTFEYRYLE 925
Cdd:COG5601   144 KERGSYVFFDPFSWSKVSLD-FLLDYKAVR 172
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
221-395 9.83e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 46.21  E-value: 9.83e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179509 221 EKYEA---DLKKEIKKLQRLRDQIKTWVASNEIkdkrqlIENRklIETQMERFKVVERETKTKaySKEGLGLAQKVDPAQ 297
Cdd:PRK03918  158 DDYENaykNLGEVIKEIKRRIERLEKFIKRTEN------IEEL--IKEKEKELEEVLREINEI--SSELPELREELEKLE 227

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179509 298 KEKEEVGQwLTNTIDTLNMQVDQFESEVESLSvqtrkkkgdkdkqDRIEGLKRHIEKHRYHVRMLETILRMLDNDSILVD 377
Cdd:PRK03918  228 KEVKELEE-LKEEIEELEKELESLEGSKRKLE-------------EKIRELEERIEELKKEIEELEEKVKELKELKEKAE 293

                         170
                  ....*....|....*...
gi 1907179509 378 AIRKIKDDVEYYVDSSQD 395
Cdd:PRK03918  294 EYIKLSEFYEEYLDELRE 311
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 476-743 1.15e-04

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 46.06  E-value: 1.15e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179509 476 SQSPAKNGSKPVHSNQHPQSPAVPPTYPSGPPPTTSALSSTPgnNGASTPAAPTSALGPKASPAPSHNSGTPapyAQAVA 555
Cdd:pfam05109 491 SPSPRDNGTESKAPDMTSPTSAVTTPTPNATSPTPAVTTPTP--NATSPTLGKTSPTSAVTTPTPNATSPTP---AVTTP 565

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179509 556 PPNASGPSNAQPRPPSAqpSGGSGGGSGGSSSNSNSGTGGGAGKQNGATSYSSVVADSPAEVTLSSS------GGSSASS 629
Cdd:pfam05109 566 TPNATIPTLGKTSPTSA--VTTPTPNATSPTVGETSPQANTTNHTLGGTSSTPVVTSPPKNATSAVTtgqhniTSSSTSS 643

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179509 630 QALGPTSGPHNPAPSTSKESSTAAPsgagnvASGSGNNSGGPSLLVPLPVNPPSSPTPSFSEAKAAGTL--LNGPPQFST 707
Cdd:pfam05109 644 MSLRPSSISETLSPSTSDNSTSHMP------LLTSAHPTGGENITQVTPASTSTHHVSTSSPAPRPGTTsqASGPGNSST 717

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|
gi 1907179509 708 TPEikaPEPLSSLKSMAERAAIS----SGIEDPVPTLHLT 743
Cdd:pfam05109 718 STK---PGEVNVTKGTPPKNATSpqapSGQKTAVPTVTST 754
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 521-662 5.27e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 43.82  E-value: 5.27e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179509 521 GASTPAAPTSALGPKASPAPSHNSGTPAPYAQAVAPPNASGPSNAQPRPPSAQPSGGSGGGSGGSSSNSnsgtgggagkQ 600
Cdd:PRK07764  389 GGAGAPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPP----------P 458

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1907179509 601 NGATSYSSVVADSPAEvtlsssggsSASSQALGPTSGPHNPAPSTSKESSTAAPSGAGNVAS 662
Cdd:PRK07764  459 AAAPSAQPAPAPAAAP---------EPTAAPAPAPPAAPAPAAAPAAPAAPAAPAGADDAAT 511
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 221-328 1.99e-03

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 41.93  E-value: 1.99e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179509 221 EKYEADLKKEIKKLQRLRDQIKTWVA--SNEIKD-KRQLIENRKLIETQMERFKVVERETKTkayskeglgLAQKVDPAQ 297
Cdd:TIGR04523 446 TNQDSVKELIIKNLDNTRESLETQLKvlSRSINKiKQNLEQKQKELKSKEKELKKLNEEKKE---------LEEKVKDLT 516

                          90       100       110
                  ....*....|....*....|....*....|.
gi 1907179509 298 KEKEEvgqwLTNTIDTLNMQVDQFESEVESL 328
Cdd:TIGR04523 517 KKISS----LKEKIEKLESEKKEKESKISDL 543
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
218-413 7.29e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 39.89  E-value: 7.29e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179509 218 NQKEKYEADLKKEIKKLQRLRDQIKtwvasneiKDKRQLIENRKLIETQMERFKVVERETKT-----KAYSKEGLGLAQK 292
Cdd:COG4372    59 EELEQLEEELEQARSELEQLEEELE--------ELNEQLQAAQAELAQAQEELESLQEEAEElqeelEELQKERQDLEQQ 130

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179509 293 VDPAQKEKEEVGQWLTNT---IDTLNMQVDQFESEVESLSvQTRKKKGDKDKQDRIEGLKRHIEKHRYHVRMLETILRML 369
Cdd:COG4372   131 RKQLEAQIAELQSEIAEReeeLKELEEQLESLQEELAALE-QELQALSEAEAEQALDELLKEANRNAEKEEELAEAEKLI 209

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 1907179509 370 DNDSI-LVDAIRKIKDDVEYYVDSSQDPDFEENEFLYDDLDLEDI 413
Cdd:COG4372   210 ESLPReLAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEE 254
 
Name Accession Description Interval E-value
Not3 pfam04065
Not1 N-terminal domain, CCR4-Not complex component;
211-408 3.00e-111

Not1 N-terminal domain, CCR4-Not complex component;


Pssm-ID: 461155 [Multi-domain]  Cd Length: 228  Bit Score: 341.45  E-value: 3.00e-111
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179509 211 LHNAANANQKEKYEADLKKEIKKLQRLRDQIKTWVASNEIKDKRQLIENRKLIETQMERFKVVERETKTKAYSKEGLGLA 290
Cdd:pfam04065  30 LESATNSSQKEKLEADLKKEIKKLQRLRDQIKTWLSSNDIKDKKKLLENRKLIEEAMERFKAVEKESKTKAFSKEGLSLA 109

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179509 291 Q--KVDPAQKEKEEVGQWLTNTIDTLNMQVDQFESEVESLSVQTRkKKGDKDKQDRIEGLKRHIEKHRYHVRMLETILRM 368
Cdd:pfam04065 110 AasKLDPKEKEKAEARDWLSDSIDELNRQIEALEAEIESLQAQKK-KKKKDSEKARLEELEKLIERHKFHIEKLELILRL 188

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 1907179509 369 LDNDSILVDAIRKIKDDVEYYVDSSQDPDFEENEFLYDDL 408
Cdd:pfam04065 189 LENGELDPEQVDDIKEDIEYYVESNQDPDFVEDEDIYDDL 228
NOT2_3_5 pfam04153
NOT2 / NOT3 / NOT5 family; NOT1, NOT2, NOT3, NOT4 and NOT5 form a nuclear complex that ...
 797-922 2.91e-56

NOT2 / NOT3 / NOT5 family; NOT1, NOT2, NOT3, NOT4 and NOT5 form a nuclear complex that negatively regulates the basal and activated transcription of many genes. This family includes NOT2, NOT3 and NOT5.


Pssm-ID: 461199  Cd Length: 121  Bit Score: 189.73  E-value: 2.91e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179509 797 AAWHHMPHPSDSERIRQYLPRNPCPTPpyhhQMPPPHSDTVEFYQRLSTETLFFIFYYLEGTKAQYLAAKALKKQSWRFH 876
Cdd:pfam04153   1 YSTFNSPWPLDAERPYEPDFRNPACYP----QEPLPRLESPEKFSKFDDETLFYIFYSMPGDYAQYLAAKELKKRSWRYH 76

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 1907179509 877 TKYMMWFQRHEEPKTITDEFEQGTYIYFDYeKWGQRKKEGFTFEYR 922
Cdd:pfam04153  77 KKLRTWFTRDEEPKVITNEYERGTYIYFDY-TWEQRRKKDFTLDYE 121
CDC36 COG5601
General negative regulator of transcription subunit [Transcription];
822-925 4.11e-14

General negative regulator of transcription subunit [Transcription];


Pssm-ID: 227888  Cd Length: 172  Bit Score: 71.16  E-value: 4.11e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179509 822 TPPYHHQMPPPHSDTVEFYQR----LSTETLFFIFYYLEGTKAQYLAAKALKKQSWRFHTKYMMW--FQRHEEPKTITDE 895
Cdd:COG5601    64 LPNCYPNAPNPPIFKVNIEDMkmdnFHDETLFYIFYSFPNDVLQEKAYDELLKRNWRFHKMLKCWltFNPGMSPATADHV 143

                          90       100       110
                  ....*....|....*....|....*....|
gi 1907179509 896 FEQGTYIYFDYEKWGQRKKEgFTFEYRYLE 925
Cdd:COG5601   144 KERGSYVFFDPFSWSKVSLD-FLLDYKAVR 172
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
221-395 9.83e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 46.21  E-value: 9.83e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179509 221 EKYEA---DLKKEIKKLQRLRDQIKTWVASNEIkdkrqlIENRklIETQMERFKVVERETKTKaySKEGLGLAQKVDPAQ 297
Cdd:PRK03918  158 DDYENaykNLGEVIKEIKRRIERLEKFIKRTEN------IEEL--IKEKEKELEEVLREINEI--SSELPELREELEKLE 227

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179509 298 KEKEEVGQwLTNTIDTLNMQVDQFESEVESLSvqtrkkkgdkdkqDRIEGLKRHIEKHRYHVRMLETILRMLDNDSILVD 377
Cdd:PRK03918  228 KEVKELEE-LKEEIEELEKELESLEGSKRKLE-------------EKIRELEERIEELKKEIEELEEKVKELKELKEKAE 293

                         170
                  ....*....|....*...
gi 1907179509 378 AIRKIKDDVEYYVDSSQD 395
Cdd:PRK03918  294 EYIKLSEFYEEYLDELRE 311
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 476-743 1.15e-04

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 46.06  E-value: 1.15e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179509 476 SQSPAKNGSKPVHSNQHPQSPAVPPTYPSGPPPTTSALSSTPgnNGASTPAAPTSALGPKASPAPSHNSGTPapyAQAVA 555
Cdd:pfam05109 491 SPSPRDNGTESKAPDMTSPTSAVTTPTPNATSPTPAVTTPTP--NATSPTLGKTSPTSAVTTPTPNATSPTP---AVTTP 565

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179509 556 PPNASGPSNAQPRPPSAqpSGGSGGGSGGSSSNSNSGTGGGAGKQNGATSYSSVVADSPAEVTLSSS------GGSSASS 629
Cdd:pfam05109 566 TPNATIPTLGKTSPTSA--VTTPTPNATSPTVGETSPQANTTNHTLGGTSSTPVVTSPPKNATSAVTtgqhniTSSSTSS 643

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179509 630 QALGPTSGPHNPAPSTSKESSTAAPsgagnvASGSGNNSGGPSLLVPLPVNPPSSPTPSFSEAKAAGTL--LNGPPQFST 707
Cdd:pfam05109 644 MSLRPSSISETLSPSTSDNSTSHMP------LLTSAHPTGGENITQVTPASTSTHHVSTSSPAPRPGTTsqASGPGNSST 717

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|
gi 1907179509 708 TPEikaPEPLSSLKSMAERAAIS----SGIEDPVPTLHLT 743
Cdd:pfam05109 718 STK---PGEVNVTKGTPPKNATSpqapSGQKTAVPTVTST 754
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 521-662 5.27e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 43.82  E-value: 5.27e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179509 521 GASTPAAPTSALGPKASPAPSHNSGTPAPYAQAVAPPNASGPSNAQPRPPSAQPSGGSGGGSGGSSSNSnsgtgggagkQ 600
Cdd:PRK07764  389 GGAGAPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPP----------P 458

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1907179509 601 NGATSYSSVVADSPAEvtlsssggsSASSQALGPTSGPHNPAPSTSKESSTAAPSGAGNVAS 662
Cdd:PRK07764  459 AAAPSAQPAPAPAAAP---------EPTAAPAPAPPAAPAPAAAPAAPAAPAAPAGADDAAT 511
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 391-672 1.39e-03

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 42.47  E-value: 1.39e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179509  391 DSSQDPDFEEN-EFLYDDLDLEDIPQALVATS----------PPSHSHMEDEIFNQSSSTPTSTTSSSPIPPSPANCTTE 459
Cdd:PHA03307    30 DAADDLLSGSQgQLVSDSAELAAVTVVAGAAAcdrfepptgpPPGPGTEAPANESRSTPTWSLSTLAPASPAREGSPTPP 109

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179509  460 NSEDDKKRGRSTDSEVSQSPAKNGSKPVHSNQHPQSPAVPPTYPSGPPPTTSALSSTPGNNGASTPAAPTSAL-----GP 534
Cdd:PHA03307   110 GPSSPDPPPPTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAALPLSSPEETarapsSP 189

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179509  535 KASPAPSHNSGTPAPYAQAVAPPNASGPSNAQPRPPSAQPSGGSGGGSGGSSSNSNSGTGGGAGKQNGATSYSSVVADSP 614
Cdd:PHA03307   190 PAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRSAADDAGASSSDSSSSESSGCGWGPENECPLPRPAPITLPTRI 269

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1907179509  615 AEVTLSSSGGSSASSQALGPTSGPHNPAPSTSKESSTAAPSGAGNVASGSGNNSGGPS 672
Cdd:PHA03307   270 WEASGWNGPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRESSSS 327
PHA03247 PHA03247
large tegument protein UL36; Provisional
 493-836 1.41e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 42.62  E-value: 1.41e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179509  493 PQSPAVPPTYPSGPPPTTSALSSTPGNNGASTPAAPTSALGPKASPAPSHNSGTPAPYA------------------QAV 554
Cdd:PHA03247  2577 PSEPAVTSRARRPDAPPQSARPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAAnepdphppptvppperprDDP 2656

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179509  555 APPNASGPSNAQ--------------PRPPSA---------------QPSGGSGGGSGGSSSNSNSGTGGGAGKQNGATS 605
Cdd:PHA03247  2657 APGRVSRPRRARrlgraaqassppqrPRRRAArptvgsltsladpppPPPTPEPAPHALVSATPLPPGPAAARQASPALP 2736

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179509  606 YSSVVADSPAEVTLSSSGGSSASSQAlgpTSGPHNPAPSTSKESSTAAPSGAGNVASGSGNNSGGPSLLVPLPVNPPSSP 685
Cdd:PHA03247  2737 AAPAPPAVPAGPATPGGPARPARPPT---TAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLA 2813

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179509  686 TPSFSEAKAAGTLLNGPPQFST-TPEIKAPEPLSSLKSM----------AERAAISSGIEDPVPTLHLTDRDIilsstsa 754
Cdd:PHA03247  2814 PAAALPPAASPAGPLPPPTSAQpTAPPPPPGPPPPSLPLggsvapggdvRRRPPSRSPAAKPAAPARPPVRRL------- 2886

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179509  755 pptsSQPPLQLSEVNIPLSlgvcPLGPVSLTKEQLYQQAMEEAAWHHMPhpsdserirqyLPRNPCPTPPYHHQMPPPHS 834
Cdd:PHA03247  2887 ----ARPAVSRSTESFALP----PDQPERPPQPQAPPPPQPQPQPPPPP-----------QPQPPPPPPPRPQPPLAPTT 2947


                   ..
gi 1907179509  835 DT 836
Cdd:PHA03247  2948 DP 2949
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 221-328 1.99e-03

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 41.93  E-value: 1.99e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179509 221 EKYEADLKKEIKKLQRLRDQIKTWVA--SNEIKD-KRQLIENRKLIETQMERFKVVERETKTkayskeglgLAQKVDPAQ 297
Cdd:TIGR04523 446 TNQDSVKELIIKNLDNTRESLETQLKvlSRSINKiKQNLEQKQKELKSKEKELKKLNEEKKE---------LEEKVKDLT 516

                          90       100       110
                  ....*....|....*....|....*....|.
gi 1907179509 298 KEKEEvgqwLTNTIDTLNMQVDQFESEVESL 328
Cdd:TIGR04523 517 KKISS----LKEKIEKLESEKKEKESKISDL 543
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 517-735 2.84e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 41.51  E-value: 2.84e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179509 517 PGNNGASTPAAPTSALGPKASPAPSHNSGTPAPyAQAVAPPNASGPSNAQPRPPSAQPSGGSGGGSGGSSSNSNSGTGGG 596
Cdd:PRK07764  592 PGAAGGEGPPAPASSGPPEEAARPAAPAAPAAP-AAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWP 670

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179509 597 AGKQNGATSYSSVVADSPAevtlsssggsSASSQALGPTSGPHNPAPSTSKESSTAAPSGAGNVASGSGNNSGGPSLLVP 676
Cdd:PRK07764  671 AKAGGAAPAAPPPAPAPAA----------PAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVP 740

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1907179509 677 LPVNPPSSPTPSFSEAKAAGTLLNGPPQFSTTPeiKAPEPLSSLKSMAERAAISSGIED 735
Cdd:PRK07764  741 LPPEPDDPPDPAGAPAQPPPPPAPAPAAAPAAA--PPPSPPSEEEEMAEDDAPSMDDED 797
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
217-328 3.02e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 41.59  E-value: 3.02e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179509 217 ANQKEKYEADLKKEIKKLQRLRDQIKTWVasneikdkrQLIENRKLIETQMERFKvvereTKTKAYSKEglGLAQKVDPA 296
Cdd:PRK03918  333 LEEKEERLEELKKKLKELEKRLEELEERH---------ELYEEAKAKKEELERLK-----KRLTGLTPE--KLEKELEEL 396

                          90       100       110
                  ....*....|....*....|....*....|..
gi 1907179509 297 QKEKEEVgqwlTNTIDTLNMQVDQFESEVESL 328
Cdd:PRK03918  397 EKAKEEI----EEEISKITARIGELKKEIKEL 424
DUF5585 pfam17823
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
 511-824 3.24e-03

Family of unknown function (DUF5585); This is a family of unknown function found in chordata.


Pssm-ID: 465521 [Multi-domain]  Cd Length: 506  Bit Score: 41.10  E-value: 3.24e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179509 511 SALSSTPGNNGASTPAA----PTSALGPKASPAPShnsgTPAPYAQAVAPPNASGPSNAQPRPPSAqpsggsgggsggss 586
Cdd:pfam17823 117 AAASSSPSSAAQSLPAAiaalPSEAFSAPRAAACR----ANASAAPRAAIAAASAPHAASPAPRTA-------------- 178

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179509 587 snsnsGTGGGAGKQNGATSYSSVVADSPAEVTLSssggssassqalgPTSGPHNPAPSTSKESSTAAPSGAGNVASGSGN 666
Cdd:pfam17823 179 -----ASSTTAASSTTAASSAPTTAASSAPATLT-------------PARGISTAATATGHPAAGTALAAVGNSSPAAGT 240

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179509 667 NSGGPSLLVPLPVNPPSSPTPSFseAKAAGTLLNGPPQfSTTPeikAPEPLSSLKSMAERAAISSGIEDPVPTLHLT-DR 745
Cdd:pfam17823 241 VTAAVGTVTPAALATLAAAAGTV--ASAAGTINMGDPH-ARRL---SPAKHMPSDTMARNPAAPMGAQAQGPIIQVStDQ 314

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179509 746 DIIlssTSAPPTSSQPPLQLSEVNIPLSLGVCPLGPVSLTKEQLYQQAmeeAAWHHMPHPSDSERIRQYLP-RNPCPTPP 824
Cdd:pfam17823 315 PVH---NTAGEPTPSPSNTTLEPNTPKSVASTNLAVVTTTKAQAKEPS---ASPVPVLHTSMIPEVEATSPtTQPSPLLP 388
PHA03247 PHA03247
large tegument protein UL36; Provisional
 486-845 5.30e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 40.69  E-value: 5.30e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179509  486 PVHSNQHPQSPavpPTYPSGPPPTTSALSSTPGNNGASTPAAPTSALGPkASPAPSHNSGTPAPYAQAVAPPNASGPsnA 565
Cdd:PHA03247  2694 SLTSLADPPPP---PPTPEPAPHALVSATPLPPGPAAARQASPALPAAP-APPAVPAGPATPGGPARPARPPTTAGP--P 2767

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179509  566 QPRPPSAQPSGGSGGGSGGSSSNSNSGTGGGAGKQNGATSYSSVVADSPAEVTLSSSGGSSASSQALGPTSGPHNPAPST 645
Cdd:PHA03247  2768 APAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPP 2847

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179509  646 SKESStaapsgAGNVASGSGNNSGGPSLLVPLPVNPPSSPTpsfseakaAGTLLNGPPQFSTTPEIKAPEPLSSLKSMAE 725
Cdd:PHA03247  2848 PSLPL------GGSVAPGGDVRRRPPSRSPAAKPAAPARPP--------VRRLARPAVSRSTESFALPPDQPERPPQPQA 2913

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179509  726 RAAISSGIEDPVPTLhltdrdiilsstsapptsSQPPLQlsevniPLSLGVCPLGPVSLTKEQLYQQAMEEAAWHHMPHP 805
Cdd:PHA03247  2914 PPPPQPQPQPPPPPQ------------------PQPPPP------PPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVP 2969

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|
gi 1907179509  806 SDSERIRQylpRNPCPTPPYHHQMPPPHSDTVEFYQRLST 845
Cdd:PHA03247  2970 GRVAVPRF---RVPQPAPSREAPASSTPPLTGHSLSRVSS 3006
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
218-413 7.29e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 39.89  E-value: 7.29e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179509 218 NQKEKYEADLKKEIKKLQRLRDQIKtwvasneiKDKRQLIENRKLIETQMERFKVVERETKT-----KAYSKEGLGLAQK 292
Cdd:COG4372    59 EELEQLEEELEQARSELEQLEEELE--------ELNEQLQAAQAELAQAQEELESLQEEAEElqeelEELQKERQDLEQQ 130

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179509 293 VDPAQKEKEEVGQWLTNT---IDTLNMQVDQFESEVESLSvQTRKKKGDKDKQDRIEGLKRHIEKHRYHVRMLETILRML 369
Cdd:COG4372   131 RKQLEAQIAELQSEIAEReeeLKELEEQLESLQEELAALE-QELQALSEAEAEQALDELLKEANRNAEKEEELAEAEKLI 209

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 1907179509 370 DNDSI-LVDAIRKIKDDVEYYVDSSQDPDFEENEFLYDDLDLEDI 413
Cdd:COG4372   210 ESLPReLAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEE 254
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
513-696 7.42e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 40.22  E-value: 7.42e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179509 513 LSSTPGNNGASTPAAPTSALGPKASPAPSHNSGTPAPYAQAVAPPNASGPSNAQPRPPSAQPSGGSGGGSGGSSSNSNSG 592
Cdd:PRK07003  356 LAFEPAVTGGGAPGGGVPARVAGAVPAPGARAAAAVGASAVPAVTAVTGAAGAALAPKAAAAAAATRAEAPPAAPAPPAT 435

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179509 593 TGGgAGKQNGATSYSSVVADSPAEVTLSSSGGSSASSQALGPTSGPHNPAPSTSK----------ESSTAAPSGAGNVAS 662
Cdd:PRK07003  436 ADR-GDDAADGDAPVPAKANARASADSRCDERDAQPPADSGSASAPASDAPPDAAfepapraaapSAATPAAVPDARAPA 514

                         170       180       190
                  ....*....|....*....|....*....|....
gi 1907179509 663 GSGNNSGGPSLLVPLPVNPPSSPTPSFSEAKAAG 696
Cdd:PRK07003  515 AASREDAPAAAAPPAPEARPPTPAAAAPAARAGG 548
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 478-657 7.75e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 39.97  E-value: 7.75e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179509 478 SPAKNGSKPVHSNQHPQSPAVPPTYPSGPPPTTSALSSTPGNNGASTPAAPTSALGPKASPAPS-------HNSGTPAPY 550
Cdd:PRK07764  600 PPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASdggdgwpAKAGGAAPA 679

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179509 551 AQAVAPPNASGPSNAQPRPPSAQPsggsgggSGGSSSNSNSGTGGGAGKQNGATSYSSVVADSPAEVTLSSSGGSSAssq 630
Cdd:PRK07764  680 APPPAPAPAAPAAPAGAAPAQPAP-------APAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPPEPDDPP--- 749

                         170       180
                  ....*....|....*....|....*..
gi 1907179509 631 ALGPTSGPHNPAPSTSKESSTAAPSGA 657
Cdd:PRK07764  750 DPAGAPAQPPPPPAPAPAAAPAAAPPP 776
PRK14971 PRK14971
DNA polymerase III subunit gamma/tau;
474-572 8.06e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237874 [Multi-domain]  Cd Length: 614  Bit Score: 39.76  E-value: 8.06e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179509 474 EVSQSPAKNGSKPvhSNQHPQSP---AVPPTYPSGPPPTTSALSSTPGNNG-ASTPAAPTSALGPKASPAP-SHNSGTPA 548
Cdd:PRK14971  358 QLAQLTQKGDDAS--GGRGPKQHikpVFTQPAAAPQPSAAAAASPSPSQSSaAAQPSAPQSATQPAGTPPTvSVDPPAAV 435

                          90       100
                  ....*....|....*....|....
gi 1907179509 549 PYAQAVAPPNASGPSNAQPRPPSA 572
Cdd:PRK14971  436 PVNPPSTAPQAVRPAQFKEEKKIP 459
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
518-728 8.95e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 39.86  E-value: 8.95e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179509 518 GNNGASTPAAPTSALGPKASPAPSHNSGTPAPYAQAVAPPNASGPSNAQPRPPSAQPSGGSGGGSGGSSSNSNSGTGGGA 597
Cdd:PRK12323  367 QSGGGAGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGPGG 446

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179509 598 GKQNGATSYSSVVADSPAEVtlsssggssassQALGPTSGPHNPAPSTSKESSTAAPSGAGNVASgsgnNSGGPSLLVPL 677
Cdd:PRK12323  447 APAPAPAPAAAPAAAARPAA------------AGPRPVAAAAAAAPARAAPAAAPAPADDDPPPW----EELPPEFASPA 510

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1907179509 678 PVNPPSSPTPSFSEAKAAGTLLNGPPQFSTTPEIKAPEPLSSLKSMAERAA 728
Cdd:PRK12323  511 PAQPDAAPAGWVAESIPDPATADPDDAFETLAPAPAAAPAPRAAAATEPVV 561
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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