|
Name |
Accession |
Description |
Interval |
E-value |
| Pyridoxal_deC |
pfam00282 |
Pyridoxal-dependent decarboxylase conserved domain; |
88-459 |
3.76e-156 |
|
Pyridoxal-dependent decarboxylase conserved domain;
Pssm-ID: 395219 Cd Length: 373 Bit Score: 450.33 E-value: 3.76e-156
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622962853 88 PNELLQEYNWELADQPQNLEDILMHCQTTLKYAIKTGH-PRYFNQLSTGLDMVGLAADWLTSTANTNMFTYEIAPVFVLL 166
Cdd:pfam00282 1 PGYLKPLLPLAAPIIPEPELQIDGDIRRNLMPGVTTWHsPHFHAYMPTGNSYPSLLGDMLTDAINCNGFTWESSPACTEL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622962853 167 EYVTLKKMREIIGWP----GGSGDGIFSPGGAISNMYAMMIARFKMFPEVKEKGMAAVP-----RLIAFTSEHSHFSLKK 237
Cdd:pfam00282 81 ENVVMNWLGEMLGLPaeflGQEGGGVLQPGSSESNLLALLAARTKWIKRMKAAGKPADSsgilaKLVAYTSDQAHSSIEK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622962853 238 GAAALGIGtdsVILIKCDERGKMIPSDLERRILEAKQKGFVPFLVSATAGTTVYGAFDPLLAVADICKKYKIWMHVDAAW 317
Cdd:pfam00282 161 AALYGGVK---LREIPSDDNGKMRGMDLEKAIEEDKENGLIPFFVVATLGTTGSGAFDDLQELGDICAKHNLWLHVDAAY 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622962853 318 GGGLLMSRKHKWKLSGVERANSVTWNPHKMMGVPLQCSALLVREEGLMQNCNQMHASYLFqqdkHYDLSYDTGDKALQCG 397
Cdd:pfam00282 238 GGSAFICPEFRHWLFGIERADSITFNPHKWMLVLLDCSAVWVKDKEALQQAFQFNPLYLG----HTDSAYDTGHKQIPLS 313
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1622962853 398 RHVDVFKLWLMWRAKGTTGFEAHVDKCLELAEYLYNIIKNREGYEMVFdgKPQHTNVCFWYI 459
Cdd:pfam00282 314 RRFRILKLWFVIRSLGVEGLQNQIRRHVELAQYLEALIRKDGRFEICA--EVGLGLVCFRLK 373
|
|
| DOPA_deC_like |
cd06450 |
DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent ... |
128-531 |
2.44e-145 |
|
DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to DOPA/tyrosine decarboxylase (DDC), histidine decarboxylase (HDC), and glutamate decarboxylase (GDC). DDC is active as a dimer and catalyzes the decarboxylation of tyrosine. GDC catalyzes the decarboxylation of glutamate and HDC catalyzes the decarboxylation of histidine.
Pssm-ID: 99743 [Multi-domain] Cd Length: 345 Bit Score: 421.61 E-value: 2.44e-145
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622962853 128 YFNQLSTGLDMVGLAADWLTSTANTNMFTYEIAPVFVLLEYVTLKKMREIIGWPGGSGDGIFSPGGAISNMYAMMIARFK 207
Cdd:cd06450 1 FLAGFVTTMDPPALLLEMLTSAKNAIDFTWDESPAATEMEAEVVNWLAKLFGLPSEDADGVFTSGGSESNLLALLAARDR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622962853 208 MFPEVKEKGMAAVPRLIAFTSEHSHFSLKKGAAALGIgtdSVILIKCDERGKMIPSDLERRILEAKQKGFVPFLVSATAG 287
Cdd:cd06450 81 ARKRLKAGGGRGIDKLVIVCSDQAHVSVEKAAAYLDV---KVRLVPVDEDGRMDPEALEAAIDEDKAEGLNPIMVVATAG 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622962853 288 TTVYGAFDPLLAVADICKKYKIWMHVDAAWGGGLLMSRKHKWKLSGVERANSVTWNPHKMMGVPLQCSALLVReeglmqn 367
Cdd:cd06450 158 TTDTGAIDPLEEIADLAEKYDLWLHVDAAYGGFLLPFPEPRHLDFGIERVDSISVDPHKYGLVPLGCSAVLVR------- 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622962853 368 cnqmhasylfqqdkhydlsydtgdkalqcgrhvdVFKLWLMWRAKGTTGFEAHVDKCLELAEYLYNIIKNREGYEMVfdG 447
Cdd:cd06450 231 ----------------------------------ALKLWATLRRFGRDGYGEHIDRIVDLAKYLAELIRADPGFELL--G 274
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622962853 448 KPQHTNVCFWYIPPslrtledneermSRLSKVAPVIKARMMEYGTTMVSYQPLGDKvNFFRMVISNPAATHQDIDFLIEE 527
Cdd:cd06450 275 EPNLSLVCFRLKPS------------VKLDELNYDLSDRLNERGGWHVPATTLGGP-NVLRFVVTNPLTTRDDADALLED 341
|
....
gi 1622962853 528 IERL 531
Cdd:cd06450 342 IERA 345
|
|
| GadA |
COG0076 |
Glutamate or tyrosine decarboxylase or a related PLP-dependent protein [Amino acid transport ... |
61-534 |
2.91e-142 |
|
Glutamate or tyrosine decarboxylase or a related PLP-dependent protein [Amino acid transport and metabolism]; Glutamate or tyrosine decarboxylase or a related PLP-dependent protein is part of the Pathway/BioSystem: Pantothenate/CoA biosynthesis
Pssm-ID: 439846 [Multi-domain] Cd Length: 460 Bit Score: 418.08 E-value: 2.91e-142
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622962853 61 LQDVMNILLQYVVKSFDRSTKVIDFHYPNELLQEYNWELADQPQNLEDIL--MHcQTTLKYAIKTGHPRYFNQLSTGLDM 138
Cdd:COG0076 2 FRALLHQALDLAADYLAGLDRPVFGPSPEELRAALDEPLPEEGLPPEEALaeLE-DLVLPGSVDWNHPRFLAFVTGGTTP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622962853 139 VGLAADWLTSTANTNMFTYEIAPVFVLLEYVTLKKMREIIGWPGGSgDGIFSPGGAISNMYAMMIARFKMFPE-VKEKGM 217
Cdd:COG0076 81 AALAADLLASALNQNMGDWDTSPAATELEREVVRWLADLLGLPEGA-GGVFTSGGTEANLLALLAARDRALARrVRAEGL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622962853 218 AAVPRLIAFTSEHSHFSLKKGAAALGIGTDSVILIKCDERGKMIPSDLERRILEAKQKGFVPFLVSATAGTTVYGAFDPL 297
Cdd:COG0076 160 PGAPRPRIVVSEEAHSSVDKAARLLGLGRDALRKVPVDEDGRMDPDALEAAIDEDRAAGLNPIAVVATAGTTNTGAIDPL 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622962853 298 LAVADICKKYKIWMHVDAAWGGGLLMSRKHKWKLSGVERANSVTWNPHKMMGVPLQCSALLVREEGLMQNCNQMHASYLF 377
Cdd:COG0076 240 AEIADIAREHGLWLHVDAAYGGFALPSPELRHLLDGIERADSITVDPHKWLYVPYGCGAVLVRDPELLREAFSFHASYLG 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622962853 378 QQDkhyDLSYDTGDKALQCGRHVDVFKLWLMWRAKGTTGFEAHVDKCLELAEYLYNIIKNREGYEMVfdGKPQHTNVCFW 457
Cdd:COG0076 320 PAD---DGVPNLGDYTLELSRRFRALKLWATLRALGREGYRELIERCIDLARYLAEGIAALPGFELL--APPELNIVCFR 394
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1622962853 458 YIPPSLRTL-EDNEErmsrlskvapvIKARMMEYGTTMVSYQPLGDKVNfFRMVISNPAATHQDIDFLIEEIERLGQD 534
Cdd:COG0076 395 YKPAGLDEEdALNYA-----------LRDRLRARGRAFLSPTKLDGRVV-LRLVVLNPRTTEDDVDALLDDLREAAAE 460
|
|
| PLN02590 |
PLN02590 |
probable tyrosine decarboxylase |
101-521 |
8.00e-41 |
|
probable tyrosine decarboxylase
Pssm-ID: 178200 [Multi-domain] Cd Length: 539 Bit Score: 154.87 E-value: 8.00e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622962853 101 DQPQNLEDILMHCQTTLKYAIKTGH-PRYFNQLSTGLDMVGLAADWLTSTANTNMFTYEIAPVFVLLEYVTLKKMREIIG 179
Cdd:PLN02590 105 ERPESLKELLDDVSKKIMPGITHWQsPSYFAYYASSTSVAGFLGEMLNAGLSVVGFTWLTSPAATELEIIVLDWLAKLLQ 184
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622962853 180 WPG-----GSGDGIFSPGGAISNMYAMMIARFKMFPEVkekGMAAVPRLIAFTSEHSHFSLKKGAAALGIGTDSVILIKC 254
Cdd:PLN02590 185 LPDhflstGNGGGVIQGTGCEAVLVVVLAARDRILKKV---GKTLLPQLVVYGSDQTHSSFRKACLIGGIHEENIRLLKT 261
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622962853 255 DERGK--MIPSDLERRILEAKQKGFVPFLVSATAGTTVYGAFDPLLAVADICKKYKIWMHVDAAWGGGLLMSRKHKWKLS 332
Cdd:PLN02590 262 DSSTNygMPPESLEEAISHDLAKGFIPFFICATVGTTSSAAVDPLVPLGNIAKKYGIWLHVDAAYAGNACICPEYRKFID 341
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622962853 333 GVERANSVTWNPHKMMGVPLQCSALLVREEGLMQNCNQMHASYLFQQDKHYDLSYDTGDKALQCGRHVDVFKLWLMWRAK 412
Cdd:PLN02590 342 GIENADSFNMNAHKWLFANQTCSPLWVKDRYSLIDALKTNPEYLEFKVSKKDTVVNYKDWQISLSRRFRSLKLWMVLRLY 421
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622962853 413 GTTGFEAHVDKCLELAEYLYNIIKNREGYEMVfdGKPQHTNVCFWYIPpslrtLEDNEERMSRLSKvapVIKARMMEYGT 492
Cdd:PLN02590 422 GSENLRNFIRDHVNLAKHFEDYVAQDPSFEVV--TTRYFSLVCFRLAP-----VDGDEDQCNERNR---ELLAAVNSTGK 491
|
410 420
....*....|....*....|....*....
gi 1622962853 493 TMVSYQPLGDKVnFFRMVISNPAATHQDI 521
Cdd:PLN02590 492 IFISHTALSGKF-VLRFAVGAPLTEEKHV 519
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| Pyridoxal_deC |
pfam00282 |
Pyridoxal-dependent decarboxylase conserved domain; |
88-459 |
3.76e-156 |
|
Pyridoxal-dependent decarboxylase conserved domain;
Pssm-ID: 395219 Cd Length: 373 Bit Score: 450.33 E-value: 3.76e-156
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622962853 88 PNELLQEYNWELADQPQNLEDILMHCQTTLKYAIKTGH-PRYFNQLSTGLDMVGLAADWLTSTANTNMFTYEIAPVFVLL 166
Cdd:pfam00282 1 PGYLKPLLPLAAPIIPEPELQIDGDIRRNLMPGVTTWHsPHFHAYMPTGNSYPSLLGDMLTDAINCNGFTWESSPACTEL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622962853 167 EYVTLKKMREIIGWP----GGSGDGIFSPGGAISNMYAMMIARFKMFPEVKEKGMAAVP-----RLIAFTSEHSHFSLKK 237
Cdd:pfam00282 81 ENVVMNWLGEMLGLPaeflGQEGGGVLQPGSSESNLLALLAARTKWIKRMKAAGKPADSsgilaKLVAYTSDQAHSSIEK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622962853 238 GAAALGIGtdsVILIKCDERGKMIPSDLERRILEAKQKGFVPFLVSATAGTTVYGAFDPLLAVADICKKYKIWMHVDAAW 317
Cdd:pfam00282 161 AALYGGVK---LREIPSDDNGKMRGMDLEKAIEEDKENGLIPFFVVATLGTTGSGAFDDLQELGDICAKHNLWLHVDAAY 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622962853 318 GGGLLMSRKHKWKLSGVERANSVTWNPHKMMGVPLQCSALLVREEGLMQNCNQMHASYLFqqdkHYDLSYDTGDKALQCG 397
Cdd:pfam00282 238 GGSAFICPEFRHWLFGIERADSITFNPHKWMLVLLDCSAVWVKDKEALQQAFQFNPLYLG----HTDSAYDTGHKQIPLS 313
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1622962853 398 RHVDVFKLWLMWRAKGTTGFEAHVDKCLELAEYLYNIIKNREGYEMVFdgKPQHTNVCFWYI 459
Cdd:pfam00282 314 RRFRILKLWFVIRSLGVEGLQNQIRRHVELAQYLEALIRKDGRFEICA--EVGLGLVCFRLK 373
|
|
| DOPA_deC_like |
cd06450 |
DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent ... |
128-531 |
2.44e-145 |
|
DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to DOPA/tyrosine decarboxylase (DDC), histidine decarboxylase (HDC), and glutamate decarboxylase (GDC). DDC is active as a dimer and catalyzes the decarboxylation of tyrosine. GDC catalyzes the decarboxylation of glutamate and HDC catalyzes the decarboxylation of histidine.
Pssm-ID: 99743 [Multi-domain] Cd Length: 345 Bit Score: 421.61 E-value: 2.44e-145
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622962853 128 YFNQLSTGLDMVGLAADWLTSTANTNMFTYEIAPVFVLLEYVTLKKMREIIGWPGGSGDGIFSPGGAISNMYAMMIARFK 207
Cdd:cd06450 1 FLAGFVTTMDPPALLLEMLTSAKNAIDFTWDESPAATEMEAEVVNWLAKLFGLPSEDADGVFTSGGSESNLLALLAARDR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622962853 208 MFPEVKEKGMAAVPRLIAFTSEHSHFSLKKGAAALGIgtdSVILIKCDERGKMIPSDLERRILEAKQKGFVPFLVSATAG 287
Cdd:cd06450 81 ARKRLKAGGGRGIDKLVIVCSDQAHVSVEKAAAYLDV---KVRLVPVDEDGRMDPEALEAAIDEDKAEGLNPIMVVATAG 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622962853 288 TTVYGAFDPLLAVADICKKYKIWMHVDAAWGGGLLMSRKHKWKLSGVERANSVTWNPHKMMGVPLQCSALLVReeglmqn 367
Cdd:cd06450 158 TTDTGAIDPLEEIADLAEKYDLWLHVDAAYGGFLLPFPEPRHLDFGIERVDSISVDPHKYGLVPLGCSAVLVR------- 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622962853 368 cnqmhasylfqqdkhydlsydtgdkalqcgrhvdVFKLWLMWRAKGTTGFEAHVDKCLELAEYLYNIIKNREGYEMVfdG 447
Cdd:cd06450 231 ----------------------------------ALKLWATLRRFGRDGYGEHIDRIVDLAKYLAELIRADPGFELL--G 274
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622962853 448 KPQHTNVCFWYIPPslrtledneermSRLSKVAPVIKARMMEYGTTMVSYQPLGDKvNFFRMVISNPAATHQDIDFLIEE 527
Cdd:cd06450 275 EPNLSLVCFRLKPS------------VKLDELNYDLSDRLNERGGWHVPATTLGGP-NVLRFVVTNPLTTRDDADALLED 341
|
....
gi 1622962853 528 IERL 531
Cdd:cd06450 342 IERA 345
|
|
| GadA |
COG0076 |
Glutamate or tyrosine decarboxylase or a related PLP-dependent protein [Amino acid transport ... |
61-534 |
2.91e-142 |
|
Glutamate or tyrosine decarboxylase or a related PLP-dependent protein [Amino acid transport and metabolism]; Glutamate or tyrosine decarboxylase or a related PLP-dependent protein is part of the Pathway/BioSystem: Pantothenate/CoA biosynthesis
Pssm-ID: 439846 [Multi-domain] Cd Length: 460 Bit Score: 418.08 E-value: 2.91e-142
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622962853 61 LQDVMNILLQYVVKSFDRSTKVIDFHYPNELLQEYNWELADQPQNLEDIL--MHcQTTLKYAIKTGHPRYFNQLSTGLDM 138
Cdd:COG0076 2 FRALLHQALDLAADYLAGLDRPVFGPSPEELRAALDEPLPEEGLPPEEALaeLE-DLVLPGSVDWNHPRFLAFVTGGTTP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622962853 139 VGLAADWLTSTANTNMFTYEIAPVFVLLEYVTLKKMREIIGWPGGSgDGIFSPGGAISNMYAMMIARFKMFPE-VKEKGM 217
Cdd:COG0076 81 AALAADLLASALNQNMGDWDTSPAATELEREVVRWLADLLGLPEGA-GGVFTSGGTEANLLALLAARDRALARrVRAEGL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622962853 218 AAVPRLIAFTSEHSHFSLKKGAAALGIGTDSVILIKCDERGKMIPSDLERRILEAKQKGFVPFLVSATAGTTVYGAFDPL 297
Cdd:COG0076 160 PGAPRPRIVVSEEAHSSVDKAARLLGLGRDALRKVPVDEDGRMDPDALEAAIDEDRAAGLNPIAVVATAGTTNTGAIDPL 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622962853 298 LAVADICKKYKIWMHVDAAWGGGLLMSRKHKWKLSGVERANSVTWNPHKMMGVPLQCSALLVREEGLMQNCNQMHASYLF 377
Cdd:COG0076 240 AEIADIAREHGLWLHVDAAYGGFALPSPELRHLLDGIERADSITVDPHKWLYVPYGCGAVLVRDPELLREAFSFHASYLG 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622962853 378 QQDkhyDLSYDTGDKALQCGRHVDVFKLWLMWRAKGTTGFEAHVDKCLELAEYLYNIIKNREGYEMVfdGKPQHTNVCFW 457
Cdd:COG0076 320 PAD---DGVPNLGDYTLELSRRFRALKLWATLRALGREGYRELIERCIDLARYLAEGIAALPGFELL--APPELNIVCFR 394
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1622962853 458 YIPPSLRTL-EDNEErmsrlskvapvIKARMMEYGTTMVSYQPLGDKVNfFRMVISNPAATHQDIDFLIEEIERLGQD 534
Cdd:COG0076 395 YKPAGLDEEdALNYA-----------LRDRLRARGRAFLSPTKLDGRVV-LRLVVLNPRTTEDDVDALLDDLREAAAE 460
|
|
| PLN02590 |
PLN02590 |
probable tyrosine decarboxylase |
101-521 |
8.00e-41 |
|
probable tyrosine decarboxylase
Pssm-ID: 178200 [Multi-domain] Cd Length: 539 Bit Score: 154.87 E-value: 8.00e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622962853 101 DQPQNLEDILMHCQTTLKYAIKTGH-PRYFNQLSTGLDMVGLAADWLTSTANTNMFTYEIAPVFVLLEYVTLKKMREIIG 179
Cdd:PLN02590 105 ERPESLKELLDDVSKKIMPGITHWQsPSYFAYYASSTSVAGFLGEMLNAGLSVVGFTWLTSPAATELEIIVLDWLAKLLQ 184
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622962853 180 WPG-----GSGDGIFSPGGAISNMYAMMIARFKMFPEVkekGMAAVPRLIAFTSEHSHFSLKKGAAALGIGTDSVILIKC 254
Cdd:PLN02590 185 LPDhflstGNGGGVIQGTGCEAVLVVVLAARDRILKKV---GKTLLPQLVVYGSDQTHSSFRKACLIGGIHEENIRLLKT 261
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622962853 255 DERGK--MIPSDLERRILEAKQKGFVPFLVSATAGTTVYGAFDPLLAVADICKKYKIWMHVDAAWGGGLLMSRKHKWKLS 332
Cdd:PLN02590 262 DSSTNygMPPESLEEAISHDLAKGFIPFFICATVGTTSSAAVDPLVPLGNIAKKYGIWLHVDAAYAGNACICPEYRKFID 341
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622962853 333 GVERANSVTWNPHKMMGVPLQCSALLVREEGLMQNCNQMHASYLFQQDKHYDLSYDTGDKALQCGRHVDVFKLWLMWRAK 412
Cdd:PLN02590 342 GIENADSFNMNAHKWLFANQTCSPLWVKDRYSLIDALKTNPEYLEFKVSKKDTVVNYKDWQISLSRRFRSLKLWMVLRLY 421
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622962853 413 GTTGFEAHVDKCLELAEYLYNIIKNREGYEMVfdGKPQHTNVCFWYIPpslrtLEDNEERMSRLSKvapVIKARMMEYGT 492
Cdd:PLN02590 422 GSENLRNFIRDHVNLAKHFEDYVAQDPSFEVV--TTRYFSLVCFRLAP-----VDGDEDQCNERNR---ELLAAVNSTGK 491
|
410 420
....*....|....*....|....*....
gi 1622962853 493 TMVSYQPLGDKVnFFRMVISNPAATHQDI 521
Cdd:PLN02590 492 IFISHTALSGKF-VLRFAVGAPLTEEKHV 519
|
|
| PLN02880 |
PLN02880 |
tyrosine decarboxylase |
101-477 |
1.37e-34 |
|
tyrosine decarboxylase
Pssm-ID: 215475 [Multi-domain] Cd Length: 490 Bit Score: 136.19 E-value: 1.37e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622962853 101 DQPQNLEDILMHCQTTLKYAIKTGH-PRYF--------------NQLSTGLDMVGLAadWLTSTANTNmftyeiapvfvl 165
Cdd:PLN02880 57 NQPETLDQVLDDVQAKILPGVTHWQsPNYFayypsnssvagflgEMLSAGLNIVGFS--WITSPAATE------------ 122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622962853 166 LEYVTLKKMREIIGWP-----GGSGDGIFSPGGAISNMYAMMIARFKMfpeVKEKGMAAVPRLIAFTSEHSHFSLKKGAA 240
Cdd:PLN02880 123 LEMIVLDWLAKLLNLPeqflsTGNGGGVIQGTASEAVLVVLLAARDRV---LRKVGKNALEKLVVYASDQTHSALQKACQ 199
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622962853 241 ALGIGTDSVILIK--CDERGKMIPSDLERRILEAKQKGFVPFLVSATAGTTVYGAFDPLLAVADICKKYKIWMHVDAAWG 318
Cdd:PLN02880 200 IAGIHPENCRLLKtdSSTNYALAPELLSEAISTDLSSGLIPFFLCATVGTTSSTAVDPLLELGKIAKSNGMWFHVDAAYA 279
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622962853 319 GGLLMSRKHKWKLSGVERANSVTWNPHKMMGVPLQCSALLVREEGLMQNCNQMHASYLFQQDKHYDLSYDTGDKALQCGR 398
Cdd:PLN02880 280 GSACICPEYRHYIDGVEEADSFNMNAHKWFLTNFDCSLLWVKDRNALIQSLSTNPEFLKNKASQANSVVDYKDWQIPLGR 359
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1622962853 399 HVDVFKLWLMWRAKGTTGFEAHVDKCLELAEYLYNIIKNREGYEMVfdGKPQHTNVCFWYIPPSlrtleDNEERMSRLS 477
Cdd:PLN02880 360 RFRSLKLWMVLRLYGVENLQSYIRNHIKLAKEFEQLVAQDSRFEVV--TPRIFSLVCFRLVPPK-----NNEDNGNKLN 431
|
|
| PRK02769 |
PRK02769 |
histidine decarboxylase; Provisional |
187-439 |
5.00e-21 |
|
histidine decarboxylase; Provisional
Pssm-ID: 235068 [Multi-domain] Cd Length: 380 Bit Score: 95.11 E-value: 5.00e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622962853 187 GIFSPGGAISNMYAMMIARfKMFPEVkekgmaavprlIAFTSEHSHFSLKKGAAALGIGTDsviLIKCDERGKMIPSDLE 266
Cdd:PRK02769 87 GYITNGGTEGNLYGCYLAR-ELFPDG-----------TLYYSKDTHYSVSKIARLLRIKSR---VITSLPNGEIDYDDLI 151
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622962853 267 RRILEAKQKgfvPFLVSATAGTTVYGAFDPLLAVADICKKYKI---WMHVDAAWGGGLLMSRKHKWKLSGVERANSVTWN 343
Cdd:PRK02769 152 SKIKENKNQ---PPIIFANIGTTMTGAIDNIKEIQEILKKIGIddyYIHADAALSGMILPFVNNPPPFSFADGIDSIAIS 228
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622962853 344 PHKMMGVPLQCSALLVREEGLMQNcnqmhasylfqqdkHYDLSY-DTGDKALQCGR--HVDVFkLWLMWRAKGTTGFEAH 420
Cdd:PRK02769 229 GHKFIGSPMPCGIVLAKKKYVERI--------------SVDVDYiGSRDQTISGSRngHTALL-LWAAIRSLGSKGLRQR 293
|
250
....*....|....*....
gi 1622962853 421 VDKCLELAEYLYNIIKNRE 439
Cdd:PRK02769 294 VQHCLDMAQYAVDRLQANG 312
|
|
| PLN03032 |
PLN03032 |
serine decarboxylase; Provisional |
221-431 |
7.39e-13 |
|
serine decarboxylase; Provisional
Pssm-ID: 166673 [Multi-domain] Cd Length: 374 Bit Score: 70.24 E-value: 7.39e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622962853 221 PRLIAFTSEHSHFSLKKGAAALGIGTDSVILIkcdERGKMIPSDLERRILEAKQKgfvPFLVSATAGTTVYGAFDPLLAV 300
Cdd:PLN03032 110 PDGILYASRESHYSVFKAARMYRMEAVKVPTL---PSGEIDYDDLERALAKNRDK---PAILNVNIGTTVKGAVDDLDRI 183
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622962853 301 ADICKKYKI-----WMHVDAAWGGGLLMSRKHKWKLSGVERANSVTWNPHKMMGVPLQCSALLVREEGLMQncnqmhasy 375
Cdd:PLN03032 184 LRILKELGYtedrfYIHCDGALFGLMMPFVSRAPEVTFRKPIGSVSVSGHKFLGCPMPCGVALTRKKHVKA--------- 254
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 1622962853 376 lFQQDKHYDLSYDTGDKALQCGrHVDVFkLWLMWRAKGTTGFEAHVDKCLELAEYL 431
Cdd:PLN03032 255 -LSQNVEYLNSRDATIMGSRNG-HAPLY-LWYTLRRKGYRGIKRDVQHCMRNAHYL 307
|
|
| PLN02263 |
PLN02263 |
serine decarboxylase |
193-431 |
8.43e-12 |
|
serine decarboxylase
Pssm-ID: 177904 [Multi-domain] Cd Length: 470 Bit Score: 67.15 E-value: 8.43e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622962853 193 GAISNMYAMMIARfKMFPEVkekgmaavprlIAFTSEHSHFSLKKGAAALGIGtdsVILIKCDERGKMIPSDLERRILEA 272
Cdd:PLN02263 161 GTEGNLHGILVGR-EVFPDG-----------ILYASRESHYSVFKAARMYRME---CVKVDTLVSGEIDCADFKAKLLAN 225
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622962853 273 KQKgfvPFLVSATAGTTVYGAFDPLLAVADICKKY-----KIWMHVDAAWGGGLLMSRKHKWKLSGVERANSVTWNPHKM 347
Cdd:PLN02263 226 KDK---PAIINVNIGTTVKGAVDDLDLVIKTLEECgfsqdRFYIHCDGALFGLMMPFVKRAPKVTFKKPIGSVSVSGHKF 302
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622962853 348 MGVPLQCSALLVREEglmqncnqmHASYLfQQDKHYDLSYDTGDKALQCGrHVDVFkLWLMWRAKGTTGFEAHVDKCLEL 427
Cdd:PLN02263 303 VGCPMPCGVQITRME---------HINVL-SSNVEYLASRDATIMGSRNG-HAPIF-LWYTLNRKGYRGFQKEVQKCLRN 370
|
....
gi 1622962853 428 AEYL 431
Cdd:PLN02263 371 AHYL 374
|
|
| AAT_I |
cd01494 |
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP) ... |
259-360 |
3.96e-11 |
|
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. Structure and sequence analysis has revealed that the PLP dependent enzymes can be classified into four major groups of different evolutionary origin: aspartate aminotransferase superfamily (fold type I), tryptophan synthase beta superfamily (fold type II), alanine racemase superfamily (fold type III), and D-amino acid superfamily (fold type IV) and Glycogen phophorylase family (fold type V).
Pssm-ID: 99742 [Multi-domain] Cd Length: 170 Bit Score: 61.63 E-value: 3.96e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622962853 259 KMIPSD------LERRILEAKQKGFVPFLVSATAGTTVYGAFDPLLAVADICKKYKIWMHVDAAWGGGllmSRKHKWKLS 332
Cdd:cd01494 67 VPVPVDdagyggLDVAILEELKAKPNVALIVITPNTTSGGVLVPLKEIRKIAKEYGILLLVDAASAGG---ASPAPGVLI 143
|
90 100
....*....|....*....|....*...
gi 1622962853 333 GVERANSVTWNPHKMMGVPlQCSALLVR 360
Cdd:cd01494 144 PEGGADVVTFSLHKNLGGE-GGGVVIVK 170
|
|
| Beta_elim_lyase |
pfam01212 |
Beta-eliminating lyase; |
230-316 |
1.79e-04 |
|
Beta-eliminating lyase;
Pssm-ID: 426128 [Multi-domain] Cd Length: 288 Bit Score: 43.36 E-value: 1.79e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622962853 230 HSHFSLKKGAAALGIGTdsVILIKCDERGKMIPSDLERRILEAKQKGFVPF-LVSAT-----AGTTVYgAFDPLLAVADI 303
Cdd:pfam01212 81 HIHFDETGGHAELGGVQ--PRPLDGDEAGNMDLEDLEAAIREVGADIFPPTgLISLEnthnsAGGQVV-SLENLREIAAL 157
|
90
....*....|...
gi 1622962853 304 CKKYKIWMHVDAA 316
Cdd:pfam01212 158 AREHGIPVHLDGA 170
|
|
| Aminotran_5 |
pfam00266 |
Aminotransferase class-V; This domain is found in amino transferases, and other enzymes ... |
252-456 |
1.57e-03 |
|
Aminotransferase class-V; This domain is found in amino transferases, and other enzymes including cysteine desulphurase EC:4.4.1.-.
Pssm-ID: 425567 [Multi-domain] Cd Length: 368 Bit Score: 41.08 E-value: 1.57e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622962853 252 IKCDERGKMIPSDLERRILEaKQKgfvpfLVSATAGTTVYGAFDPLLAVADICKKYKIWMHVDAAWGgglLMSRKHKWKL 331
Cdd:pfam00266 119 LPLDEDGLLDLDELEKLITP-KTK-----LVAITHVSNVTGTIQPVPEIGKLAHQYGALVLVDAAQA---IGHRPIDVQK 189
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622962853 332 SGVERANSVTwnpHKMMGvPLQCSALLVREEGLmqncNQMH-----ASYLFQQDKHYDLSYDTGDK----------ALQC 396
Cdd:pfam00266 190 LGVDFLAFSG---HKLYG-PTGIGVLYGRRDLL----EKMPpllggGGMIETVSLQESTFADAPWKfeagtpniagIIGL 261
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622962853 397 GRHVDvfklWLMwrakgTTGFEAHVDKCLELAEYLYNIIKNREGYEmVFDGKPQHTNVCF 456
Cdd:pfam00266 262 GAALE----YLS-----EIGLEAIEKHEHELAQYLYERLLSLPGIR-LYGPERRASIISF 311
|
|
| Orn_deC_like |
cd00615 |
Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent ... |
289-374 |
3.00e-03 |
|
Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine decarboxylase (LDC). ODC is a dodecamer composed of six homodimers and catalyzes the decarboxylation of tryptophan. ADC catalyzes the decarboxylation of arginine and LDC catalyzes the decarboxylation of lysine. Members of this family are widely found in all three forms of life.
Pssm-ID: 99739 [Multi-domain] Cd Length: 294 Bit Score: 39.92 E-value: 3.00e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622962853 289 TVYGAFDPLLAVADICKKYKIWMHVDAAWGGGLLMS---RKHKWKLSGVERANSVtwnpHKMMGVPLQCSALLVREEGL- 364
Cdd:cd00615 164 TYYGICYNLRKIVEEAHHRGLPVLVDEAHGAHFRFHpilPSSAAMAGADIVVQST----HKTLPALTQGSMIHVKGDLVn 239
|
90
....*....|...
gi 1622962853 365 ---MQNCNQMHAS 374
Cdd:cd00615 240 pdrVNEALNLHQS 252
|
|
| |
