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Conserved domains on  [gi|1622825618|ref|XP_028700558|]
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zinc finger MYM-type protein 4 isoform X4 [Macaca mulatta]

Protein Classification

eL24 family ribosomal protein( domain architecture ID 10534361)

eL24 family ribosomal protein such as archaea 50S ribosomal protein L24, and algae 60S ribosomal protein L24

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DUF3504 pfam12012
Domain of unknown function (DUF3504); This presumed domain is functionally uncharacterized. ...
 1033-1203 7.99e-87

Domain of unknown function (DUF3504); This presumed domain is functionally uncharacterized. This domain is found in eukaryotes. This domain is typically between 156 to 173 amino acids in length.


:

Pssm-ID: 463430  Cd Length: 162  Bit Score: 278.38  E-value: 7.99e-87
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622825618 1033 MFSRIEEEHLWECKQLGAYSPIVLLNTLLFFNTKYFQLKNVTEHLKLSFAHVMRRTRTLKYsTKMTYLRFFPPlqkqese 1112
Cdd:pfam12012    1 VFSRVEEEHLWECKQLGAHSPIVLLNTLVYFNTKYFNLRTVEEHRRLSFSNVVRHTKPNPR-EKSTYLRYYEP------- 72

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622825618 1113 PDKLTVGKRKRNEDDEVPVgVEMAENTDNPLRCPVRLYEFYLSKCSESVKQRNDVFYLQPERSCVPNSPMWYSTFPIDPG 1192
Cdd:pfam12012   73 PDQVETGGRKKRDEGVNKV-VEQHENSENPLRCPVKLYEFYLSKCPESVKQRKDVFYLQPEPSCVPDSPLWYSSQPLGRN 151

                          170
                   ....*....|.
gi 1622825618 1193 TLDTMLTRILM 1203
Cdd:pfam12012  152 TLESMLTRILL 162
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 157-197 2.94e-06

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


:

Pssm-ID: 428958  Cd Length: 40  Bit Score: 45.05  E-value: 2.94e-06
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|.
gi 1622825618  157 LTMNCCENCGGYCYSGSGQcHMLQIEGQSKKFCSSSCITAY 197
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTV-IVLQNDGSVGQFCSQSCLDSY 40
TRASH smart00746
metallochaperone-like domain;
65-105 2.16e-05

metallochaperone-like domain;


:

Pssm-ID: 214799  Cd Length: 39  Bit Score: 42.75  E-value: 2.16e-05
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|.
gi 1622825618    65 CSSCSKDILNPKDVISAQFENTTtsKDFCSQSCLSTYELKK 105
Cdd:smart00746    1 CSFCGKDIYNPGTGIMVVNDGKV--YYFCSSKCLSKFKKKR 39
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 12-49 6.99e-04

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


:

Pssm-ID: 428958  Cd Length: 40  Bit Score: 38.51  E-value: 6.99e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 1622825618   12 AVRVSCSGCKKILQKGQTAY--QRKGSTQLFCSTLCLTGY 49
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTVIvlQNDGSVGQFCSQSCLDSY 40
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 401-436 2.13e-03

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


:

Pssm-ID: 428958  Cd Length: 40  Bit Score: 36.97  E-value: 2.13e-03
                           10        20        30
                   ....*....|....*....|....*....|....*....
gi 1622825618  401 VMAMCEYCKIEKIVKET---VRFSGADKSFCSEGCKLLY 436
Cdd:pfam06467    2 VKATCWFCKKLIKNKPTvivLQNDGSVGQFCSQSCLDSY 40
TRASH smart00746
metallochaperone-like domain;
207-245 9.54e-03

metallochaperone-like domain;


:

Pssm-ID: 214799  Cd Length: 39  Bit Score: 35.05  E-value: 9.54e-03
                            10        20        30
                    ....*....|....*....|....*....|....*....
gi 1622825618   207 CALCKSLRSSAEMIENTNSLGKTELFCSVNCLSAYRVKM 245
Cdd:smart00746    1 CSFCGKDIYNPGTGIMVVNDGKVYYFCSSKCLSKFKKKR 39
 
Name Accession Description Interval E-value
DUF3504 pfam12012
Domain of unknown function (DUF3504); This presumed domain is functionally uncharacterized. ...
 1033-1203 7.99e-87

Domain of unknown function (DUF3504); This presumed domain is functionally uncharacterized. This domain is found in eukaryotes. This domain is typically between 156 to 173 amino acids in length.


Pssm-ID: 463430  Cd Length: 162  Bit Score: 278.38  E-value: 7.99e-87
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622825618 1033 MFSRIEEEHLWECKQLGAYSPIVLLNTLLFFNTKYFQLKNVTEHLKLSFAHVMRRTRTLKYsTKMTYLRFFPPlqkqese 1112
Cdd:pfam12012    1 VFSRVEEEHLWECKQLGAHSPIVLLNTLVYFNTKYFNLRTVEEHRRLSFSNVVRHTKPNPR-EKSTYLRYYEP------- 72

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622825618 1113 PDKLTVGKRKRNEDDEVPVgVEMAENTDNPLRCPVRLYEFYLSKCSESVKQRNDVFYLQPERSCVPNSPMWYSTFPIDPG 1192
Cdd:pfam12012   73 PDQVETGGRKKRDEGVNKV-VEQHENSENPLRCPVKLYEFYLSKCPESVKQRKDVFYLQPEPSCVPDSPLWYSSQPLGRN 151

                          170
                   ....*....|.
gi 1622825618 1193 TLDTMLTRILM 1203
Cdd:pfam12012  152 TLESMLTRILL 162
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 157-197 2.94e-06

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 45.05  E-value: 2.94e-06
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|.
gi 1622825618  157 LTMNCCENCGGYCYSGSGQcHMLQIEGQSKKFCSSSCITAY 197
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTV-IVLQNDGSVGQFCSQSCLDSY 40
TRASH smart00746
metallochaperone-like domain;
65-105 2.16e-05

metallochaperone-like domain;


Pssm-ID: 214799  Cd Length: 39  Bit Score: 42.75  E-value: 2.16e-05
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|.
gi 1622825618    65 CSSCSKDILNPKDVISAQFENTTtsKDFCSQSCLSTYELKK 105
Cdd:smart00746    1 CSFCGKDIYNPGTGIMVVNDGKV--YYFCSSKCLSKFKKKR 39
TRASH smart00746
metallochaperone-like domain;
162-200 2.36e-05

metallochaperone-like domain;


Pssm-ID: 214799  Cd Length: 39  Bit Score: 42.36  E-value: 2.36e-05
                            10        20        30
                    ....*....|....*....|....*....|....*....
gi 1622825618   162 CENCGGYCYSGSGQcHMLQIEGQSKKFCSSSCITAYKQK 200
Cdd:smart00746    1 CSFCGKDIYNPGTG-IMVVNDGKVYYFCSSKCLSKFKKK 38
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 60-101 1.85e-04

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 40.05  E-value: 1.85e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|..
gi 1622825618   60 LTKKTCSSCSKDILNPKDVIsaQFENTTTSKDFCSQSCLSTY 101
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTVI--VLQNDGSVGQFCSQSCLDSY 40
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 12-49 6.99e-04

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 38.51  E-value: 6.99e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 1622825618   12 AVRVSCSGCKKILQKGQTAY--QRKGSTQLFCSTLCLTGY 49
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTVIvlQNDGSVGQFCSQSCLDSY 40
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 401-436 2.13e-03

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 36.97  E-value: 2.13e-03
                           10        20        30
                   ....*....|....*....|....*....|....*....
gi 1622825618  401 VMAMCEYCKIEKIVKET---VRFSGADKSFCSEGCKLLY 436
Cdd:pfam06467    2 VKATCWFCKKLIKNKPTvivLQNDGSVGQFCSQSCLDSY 40
TRASH smart00746
metallochaperone-like domain;
207-245 9.54e-03

metallochaperone-like domain;


Pssm-ID: 214799  Cd Length: 39  Bit Score: 35.05  E-value: 9.54e-03
                            10        20        30
                    ....*....|....*....|....*....|....*....
gi 1622825618   207 CALCKSLRSSAEMIENTNSLGKTELFCSVNCLSAYRVKM 245
Cdd:smart00746    1 CSFCGKDIYNPGTGIMVVNDGKVYYFCSSKCLSKFKKKR 39
 
Name Accession Description Interval E-value
DUF3504 pfam12012
Domain of unknown function (DUF3504); This presumed domain is functionally uncharacterized. ...
 1033-1203 7.99e-87

Domain of unknown function (DUF3504); This presumed domain is functionally uncharacterized. This domain is found in eukaryotes. This domain is typically between 156 to 173 amino acids in length.


Pssm-ID: 463430  Cd Length: 162  Bit Score: 278.38  E-value: 7.99e-87
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622825618 1033 MFSRIEEEHLWECKQLGAYSPIVLLNTLLFFNTKYFQLKNVTEHLKLSFAHVMRRTRTLKYsTKMTYLRFFPPlqkqese 1112
Cdd:pfam12012    1 VFSRVEEEHLWECKQLGAHSPIVLLNTLVYFNTKYFNLRTVEEHRRLSFSNVVRHTKPNPR-EKSTYLRYYEP------- 72

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622825618 1113 PDKLTVGKRKRNEDDEVPVgVEMAENTDNPLRCPVRLYEFYLSKCSESVKQRNDVFYLQPERSCVPNSPMWYSTFPIDPG 1192
Cdd:pfam12012   73 PDQVETGGRKKRDEGVNKV-VEQHENSENPLRCPVKLYEFYLSKCPESVKQRKDVFYLQPEPSCVPDSPLWYSSQPLGRN 151

                          170
                   ....*....|.
gi 1622825618 1193 TLDTMLTRILM 1203
Cdd:pfam12012  152 TLESMLTRILL 162
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 157-197 2.94e-06

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 45.05  E-value: 2.94e-06
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|.
gi 1622825618  157 LTMNCCENCGGYCYSGSGQcHMLQIEGQSKKFCSSSCITAY 197
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTV-IVLQNDGSVGQFCSQSCLDSY 40
TRASH smart00746
metallochaperone-like domain;
65-105 2.16e-05

metallochaperone-like domain;


Pssm-ID: 214799  Cd Length: 39  Bit Score: 42.75  E-value: 2.16e-05
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|.
gi 1622825618    65 CSSCSKDILNPKDVISAQFENTTtsKDFCSQSCLSTYELKK 105
Cdd:smart00746    1 CSFCGKDIYNPGTGIMVVNDGKV--YYFCSSKCLSKFKKKR 39
TRASH smart00746
metallochaperone-like domain;
162-200 2.36e-05

metallochaperone-like domain;


Pssm-ID: 214799  Cd Length: 39  Bit Score: 42.36  E-value: 2.36e-05
                            10        20        30
                    ....*....|....*....|....*....|....*....
gi 1622825618   162 CENCGGYCYSGSGQcHMLQIEGQSKKFCSSSCITAYKQK 200
Cdd:smart00746    1 CSFCGKDIYNPGTG-IMVVNDGKVYYFCSSKCLSKFKKK 38
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 60-101 1.85e-04

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 40.05  E-value: 1.85e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|..
gi 1622825618   60 LTKKTCSSCSKDILNPKDVIsaQFENTTTSKDFCSQSCLSTY 101
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTVI--VLQNDGSVGQFCSQSCLDSY 40
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 12-49 6.99e-04

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 38.51  E-value: 6.99e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 1622825618   12 AVRVSCSGCKKILQKGQTAY--QRKGSTQLFCSTLCLTGY 49
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTVIvlQNDGSVGQFCSQSCLDSY 40
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 401-436 2.13e-03

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 36.97  E-value: 2.13e-03
                           10        20        30
                   ....*....|....*....|....*....|....*....
gi 1622825618  401 VMAMCEYCKIEKIVKET---VRFSGADKSFCSEGCKLLY 436
Cdd:pfam06467    2 VKATCWFCKKLIKNKPTvivLQNDGSVGQFCSQSCLDSY 40
TRASH smart00746
metallochaperone-like domain;
207-245 9.54e-03

metallochaperone-like domain;


Pssm-ID: 214799  Cd Length: 39  Bit Score: 35.05  E-value: 9.54e-03
                            10        20        30
                    ....*....|....*....|....*....|....*....
gi 1622825618   207 CALCKSLRSSAEMIENTNSLGKTELFCSVNCLSAYRVKM 245
Cdd:smart00746    1 CSFCGKDIYNPGTGIMVVNDGKVYYFCSSKCLSKFKKKR 39
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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