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Conserved domains on  [gi|1622846561|ref|XP_028685690|]
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anaphase-promoting complex subunit 7 isoform X2 [Macaca mulatta]

Protein Classification

tetratricopeptide repeat protein( domain architecture ID 19960403)

tetratricopeptide repeat (TPR) protein may adopt a right-handed helical structure with an amphipathic channel and may function as an interaction scaffold in the formation of multi-protein complexes

CATH:  1.25.40.10
Gene Ontology:  GO:0005515
PubMed:  10517866|30708253
SCOP:  3001345

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 238-450 1.02e-18

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 85.94  E-value: 1.02e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622846561 238 AEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYL 317
Cdd:COG2956     8 ALGWYFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYL 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622846561 318 ASNSIREAMVMANNVYKTLGANAQTLTLLATVCLE--DPvtqEKAKTLLDKALTQRPDYIKAVVKKAELLSREQKYEDGI 395
Cdd:COG2956    88 KAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQegDW---EKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAI 164

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1622846561 396 ALLRNALANQSDCV-LHRILGDFLVAVNEYQEAMDQYSIALSLDPNDQKSLEGMQK 450
Cdd:COG2956   165 EALEKALKLDPDCArALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAE 220
PEP_TPR_lipo super family cl37187
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 32-325 1.27e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


The actual alignment was detected with superfamily member TIGR02917:

Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 48.16  E-value: 1.27e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622846561  32 PSEIEVKYKMAECYTMLKQDKDAIAILDGIPSRQR-TPKINMMLANLYKKAGQERPSVTSYKEVLRQCP---LALdAILG 107
Cdd:TIGR02917 564 PQEIEPALALAQYYLGKGQLKKALAILNEAADAAPdSPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPdsaLAL-LLLA 642

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622846561 108 LLSLSVKG-AEVASMTMNVIQTVPNLdWLSVWIKAYAFVHTGDNSRAINTICSLEKKSLLRDNVDLLgsLADLYFRAGDN 186
Cdd:TIGR02917 643 DAYAVMKNyAKAITSLKRALELKPDN-TEAQIGLAQLLLAAKRTESAKKIAKSLQKQHPKAALGFEL--EGDLYLRQKDY 719

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622846561 187 KNSVLKFEQAQMLDPYLIKGMDVYGYLLAR------EGRLEDV-----------------------ENLGCRLFNISDQH 237
Cdd:TIGR02917 720 PAAIQAYRKALKRAPSSQNAIKLHRALLASgntaeaVKTLEAWlkthpndavlrtalaelylaqkdYDKAIKHYQTVVKK 799

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622846561 238 AE--PWVVSGCHSFYSKRY-SRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIE 314
Cdd:TIGR02917 800 APdnAVVLNNLAWLYLELKdPRALEYAERALKLAPNIPAILDTLGWLLVEKGEADRALPLLRKAVNIAPEAAAIRYHLAL 879

                         330
                  ....*....|.
gi 1622846561 315 CYLASNSIREA 325
Cdd:TIGR02917 880 ALLATGRKAEA 890
 
Name Accession Description Interval E-value
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 238-450 1.02e-18

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 85.94  E-value: 1.02e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622846561 238 AEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYL 317
Cdd:COG2956     8 ALGWYFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYL 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622846561 318 ASNSIREAMVMANNVYKTLGANAQTLTLLATVCLE--DPvtqEKAKTLLDKALTQRPDYIKAVVKKAELLSREQKYEDGI 395
Cdd:COG2956    88 KAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQegDW---EKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAI 164

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1622846561 396 ALLRNALANQSDCV-LHRILGDFLVAVNEYQEAMDQYSIALSLDPNDQKSLEGMQK 450
Cdd:COG2956   165 EALEKALKLDPDCArALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAE 220
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 78-468 7.33e-09

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 58.56  E-value: 7.33e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622846561  78 YKKAGQERPSVTSYKEVLRQCPLALDA--ILGLLSL---SVKGAE-----VASMTMNVIQTVPNLdwlsvwikAYAFVHT 147
Cdd:TIGR02917  32 YLQKNKYKAAIIQLKNALQKDPNDAEArfLLGKIYLalgDYAAAEkelrkALSLGYPKNQVLPLL--------ARAYLLQ 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622846561 148 GDNSRAINTicsLEKKSLLRDN--VDLLGSLADLYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVYGYLLAREGRLEDVEN 225
Cdd:TIGR02917 104 GKFQQVLDE---LPGKTLLDDEgaAELLALRGLAYLGLGQLELAQKSYEQALAIDPRSLYAKLGLAQLALAENRFDEARA 180

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622846561 226 LGCRLFNISDQHAEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCR 305
Cdd:TIGR02917 181 LIDEVLTADPGNVDALLLKGDLLLSLGNIELALAAYRKAIALRPNNIAVLLALATILIEAGEFEEAEKHADALLKKAPNS 260

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622846561 306 LDC--YEGLIEcyLASNSIREAMvmaNNVYKTLGANAQTLT--LLATVCLEDPVTQEKAKTLLDKALTQRPDYIKAVVKK 381
Cdd:TIGR02917 261 PLAhyLKALVD--FQKKNYEDAR---ETLQDALKSAPEYLPalLLAGASEYQLGNLEQAYQYLNQILKYAPNSHQARRLL 335

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622846561 382 AELLSREQKYEDGIALLRNALA-NQSDCVLHRILGDFLVAVNEYQEAMDQYSIALSLDPND-----QKSLEGMQKMEKEE 455
Cdd:TIGR02917 336 ASIQLRLGRVDEAIATLSPALGlDPDDPAALSLLGEAYLALGDFEKAAEYLAKATELDPENaaartQLGISKLSQGDPSE 415

                         410
                  ....*....|...
gi 1622846561 456 SPTDATQEEDVDD 468
Cdd:TIGR02917 416 AIADLETAAQLDP 428
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 32-325 1.27e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 48.16  E-value: 1.27e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622846561  32 PSEIEVKYKMAECYTMLKQDKDAIAILDGIPSRQR-TPKINMMLANLYKKAGQERPSVTSYKEVLRQCP---LALdAILG 107
Cdd:TIGR02917 564 PQEIEPALALAQYYLGKGQLKKALAILNEAADAAPdSPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPdsaLAL-LLLA 642

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622846561 108 LLSLSVKG-AEVASMTMNVIQTVPNLdWLSVWIKAYAFVHTGDNSRAINTICSLEKKSLLRDNVDLLgsLADLYFRAGDN 186
Cdd:TIGR02917 643 DAYAVMKNyAKAITSLKRALELKPDN-TEAQIGLAQLLLAAKRTESAKKIAKSLQKQHPKAALGFEL--EGDLYLRQKDY 719

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622846561 187 KNSVLKFEQAQMLDPYLIKGMDVYGYLLAR------EGRLEDV-----------------------ENLGCRLFNISDQH 237
Cdd:TIGR02917 720 PAAIQAYRKALKRAPSSQNAIKLHRALLASgntaeaVKTLEAWlkthpndavlrtalaelylaqkdYDKAIKHYQTVVKK 799

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622846561 238 AE--PWVVSGCHSFYSKRY-SRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIE 314
Cdd:TIGR02917 800 APdnAVVLNNLAWLYLELKdPRALEYAERALKLAPNIPAILDTLGWLLVEKGEADRALPLLRKAVNIAPEAAAIRYHLAL 879

                         330
                  ....*....|.
gi 1622846561 315 CYLASNSIREA 325
Cdd:TIGR02917 880 ALLATGRKAEA 890
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
179-303 1.21e-04

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 40.92  E-value: 1.21e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622846561 179 LYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVYGYLLAREGRLEDVENLgcrlfnisdqhaepwvvsgchsfyskrysral 258
Cdd:COG3063     1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIAL-------------------------------- 48

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 1622846561 259 ylgAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAP 303
Cdd:COG3063    49 ---EKALKLDPNNAEALLNLAELLLELGDYDEALAYLERALELDP 90
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 272-303 1.09e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 36.66  E-value: 1.09e-03
                           10        20        30
                   ....*....|....*....|....*....|..
gi 1622846561  272 VQALLLKGAALRNMGRVQEAIIHFREAIRLAP 303
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDP 32
TPR_2 pfam07719
Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats ...
 272-303 1.61e-03

Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats (TPR) that are not matched by pfam00515.


Pssm-ID: 429619 [Multi-domain]  Cd Length: 33  Bit Score: 35.96  E-value: 1.61e-03
                          10        20        30
                  ....*....|....*....|....*....|..
gi 1622846561 272 VQALLLKGAALRNMGRVQEAIIHFREAIRLAP 303
Cdd:pfam07719   1 AEALYNLGLAYYKLGDYEEALEAYEKALELDP 32
 
Name Accession Description Interval E-value
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 238-450 1.02e-18

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 85.94  E-value: 1.02e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622846561 238 AEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYL 317
Cdd:COG2956     8 ALGWYFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYL 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622846561 318 ASNSIREAMVMANNVYKTLGANAQTLTLLATVCLE--DPvtqEKAKTLLDKALTQRPDYIKAVVKKAELLSREQKYEDGI 395
Cdd:COG2956    88 KAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQegDW---EKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAI 164

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1622846561 396 ALLRNALANQSDCV-LHRILGDFLVAVNEYQEAMDQYSIALSLDPNDQKSLEGMQK 450
Cdd:COG2956   165 EALEKALKLDPDCArALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAE 220
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 252-462 1.68e-18

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 85.55  E-value: 1.68e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622846561 252 KRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMVMANN 331
Cdd:COG2956    56 GEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLER 135

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622846561 332 VYKTLGANAQTLTLLATVCLE--DPvtqEKAKTLLDKALTQRPDYIKAVVKKAELLSREQKYEDGIALLRNALA-NQSDC 408
Cdd:COG2956   136 LLKLGPENAHAYCELAELYLEqgDY---DEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEqDPDYL 212

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1622846561 409 VLHRILGDFLVAVNEYQEAMDQYSIALSLDPNDQKSLEGMQKMEKEESPTDATQ 462
Cdd:COG2956   213 PALPRLAELYEKLGDPEEALELLRKALELDPSDDLLLALADLLERKEGLEAALA 266
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
265-441 3.56e-16

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 78.12  E-value: 3.56e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622846561 265 IQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMVMANNVYKTLGANAQTLT 344
Cdd:COG0457     1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALN 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622846561 345 LLATVC--LEDPvtqEKAKTLLDKALTQRPDYIKAVVKKAELLSREQKYEDGIALLRNALANQSDCV-LHRILGDFLVAV 421
Cdd:COG0457    81 NLGLALqaLGRY---EEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDAdALYNLGIALEKL 157

                         170       180
                  ....*....|....*....|
gi 1622846561 422 NEYQEAMDQYSIALSLDPND 441
Cdd:COG0457   158 GRYEEALELLEKLEAAALAA 177
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 253-443 5.75e-16

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 80.81  E-value: 5.75e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622846561 253 RYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMvmannv 332
Cdd:COG3914    59 LLALAAGEAAAAAAALLLLAALLELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEAL------ 132

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622846561 333 yktlganaqtltllatvcledpvtqekakTLLDKALTQRPDYIKAVVKKAELLSREQKYEDGIALLRNALANQSDCV-LH 411
Cdd:COG3914   133 -----------------------------AALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAeAL 183

                         170       180       190
                  ....*....|....*....|....*....|..
gi 1622846561 412 RILGDFLVAVNEYQEAMDQYSIALSLDPNDQK 443
Cdd:COG3914   184 NNLGNALQDLGRLEEAIAAYRRALELDPDNAD 215
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 176-438 9.48e-16

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 77.46  E-value: 9.48e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622846561 176 LADLYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVYGYLLAREGRLEDVENLGCRLFNISDQHAEPWVVSGCHSFYSKRYS 255
Cdd:COG2956    14 KGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLD 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622846561 256 RALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMVMANNVYKT 335
Cdd:COG2956    94 RAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKL 173

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622846561 336 LGANAQTLTLLATVCLE--DPvtqEKAKTLLDKALTQRPDYIKAVVKKAELLSREQKYEDGIALLRNALANQSDCVLHRI 413
Cdd:COG2956   174 DPDCARALLLLAELYLEqgDY---EEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSDDLLLA 250

                         250       260
                  ....*....|....*....|....*
gi 1622846561 414 LGDFLVAVNEYQEAMDQYSIALSLD 438
Cdd:COG2956   251 LADLLERKEGLEAALALLERQLRRH 275
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 141-371 8.12e-14

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 71.68  E-value: 8.12e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622846561 141 AYAFVHTGDNSRAINTICSLEKKSllRDNVDLLGSLADLYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVYGYLLAREGRL 220
Cdd:COG2956    49 GNLYRRRGEYDRAIRIHQKLLERD--PDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDW 126

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622846561 221 EDVENLGCRLFNISDQHAEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIR 300
Cdd:COG2956   127 EKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALE 206

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1622846561 301 LAPCRLDCYEGLIECYLASNSIREAMVMANNVYKTLGANAQTLTLLAtvCLEDPVTQEKAKTLLDKALTQR 371
Cdd:COG2956   207 QDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSDDLLLALAD--LLERKEGLEAALALLERQLRRH 275
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
168-403 1.82e-13

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 70.04  E-value: 1.82e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622846561 168 DNVDLLGSLADLYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVYGYLLAREGRLEDVENLGCRLFNISDQHAEPWVVSGCH 247
Cdd:COG0457     6 DDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLA 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622846561 248 SFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMV 327
Cdd:COG0457    86 LQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALE 165

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622846561 328 M----ANNVYKTLGANAQTLTLLATVCLEDPVTQEKAKTLLDKALTQRPDYIKAVVKKAELLSREQKYEDGIALLRNALA 403
Cdd:COG0457   166 LleklEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALALLLALRLAALALYQYRA 245
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 166-325 8.98e-12

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 67.33  E-value: 8.98e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622846561 166 LRDNVDLLGSLADLYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVYGYLLAREGRLEDVENLGCRLFNISDQHAEPWVVSG 245
Cdd:COG3914    74 LLLLAALLELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLG 153

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622846561 246 CHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIREA 325
Cdd:COG3914   154 EALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNLLFALRQACDWEVY 233
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
199-440 3.68e-11

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 63.10  E-value: 3.68e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622846561 199 LDPYLIKGMDVYGYLLAREGRLEDVENLGCRLFNISDQHAEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLK 278
Cdd:COG0457     3 LDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNL 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622846561 279 GAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMVMANNVYKTLGANAQTLTLLAtVCLEDPVTQE 358
Cdd:COG0457    83 GLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLG-IALEKLGRYE 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622846561 359 KAKTLLDKALTQRPDYIKAVVKKAELLSREQKYEDGIALLRNALANQSDCVLHRILGDFLVAVNEYQEAMDQYSIALSLD 438
Cdd:COG0457   162 EALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALALLLALRLAALALY 241


                  ..
gi 1622846561 439 PN 440
Cdd:COG0457   242 QY 243
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 176-377 4.25e-11

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 65.40  E-value: 4.25e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622846561 176 LADLYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVYGYLLAREGRLEDVENLGCRLFNISDQHAEPWVVSGCHSFYS---- 251
Cdd:COG3914     7 LALAALAAAALLAAAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLElaal 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622846561 252 -----KRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIREAM 326
Cdd:COG3914    87 llqalGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAI 166

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1622846561 327 VMANNVYKTLGANAQTLTLLATVcLEDPVTQEKAKTLLDKALTQRPDYIKA 377
Cdd:COG3914   167 AALRRALELDPDNAEALNNLGNA-LQDLGRLEEAIAAYRRALELDPDNADA 216
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 211-346 4.72e-11

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 65.01  E-value: 4.72e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622846561 211 GYLLAREGRLEDVENLGCRLFNISDQHAEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQE 290
Cdd:COG3914    85 ALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEE 164

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1622846561 291 AIIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMVMANNVYKTLGANAQTLTLL 346
Cdd:COG3914   165 AIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNL 220
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 269-441 7.79e-10

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 57.12  E-value: 7.79e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622846561 269 SNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMVmannvyktlganaqtltllat 348
Cdd:COG4783     1 AACAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIV--------------------- 59

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622846561 349 vcledpvtqekaktLLDKALTQRPDYIKAVVKKAELLSREQKYEDGIALLRNALANQSDCV-LHRILGDFLVAVNEYQEA 427
Cdd:COG4783    60 --------------LLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALKLDPEHPeAYLRLARAYRALGRPDEA 125

                         170
                  ....*....|....
gi 1622846561 428 MDQYSIALSLDPND 441
Cdd:COG4783   126 IAALEKALELDPDD 139
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 235-407 1.52e-09

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 56.35  E-value: 1.52e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622846561 235 DQHAEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPcrldcYEGLIE 314
Cdd:COG4783     1 AACAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDP-----DEPEAR 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622846561 315 CYLAsnsirEAMVMANNVyktlganaqtltllatvcledpvtqEKAKTLLDKALTQRPDYIKAVVKKAELLSREQKYEDG 394
Cdd:COG4783    76 LNLG-----LALLKAGDY-------------------------DEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEA 125

                         170
                  ....*....|...
gi 1622846561 395 IALLRNALANQSD 407
Cdd:COG4783   126 IAALEKALELDPD 138
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 263-384 2.96e-09

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 55.01  E-value: 2.96e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622846561 263 KAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMVMANNVYKTLGANAQT 342
Cdd:COG4235     8 QALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEA 87

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 1622846561 343 LTLLATVCLE--DPvtqEKAKTLLDKALTQRPDYIKAVVKKAEL 384
Cdd:COG4235    88 LYLLGLAAFQqgDY---AEAIAAWQKLLALLPADAPARLLEASI 128
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 78-468 7.33e-09

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 58.56  E-value: 7.33e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622846561  78 YKKAGQERPSVTSYKEVLRQCPLALDA--ILGLLSL---SVKGAE-----VASMTMNVIQTVPNLdwlsvwikAYAFVHT 147
Cdd:TIGR02917  32 YLQKNKYKAAIIQLKNALQKDPNDAEArfLLGKIYLalgDYAAAEkelrkALSLGYPKNQVLPLL--------ARAYLLQ 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622846561 148 GDNSRAINTicsLEKKSLLRDN--VDLLGSLADLYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVYGYLLAREGRLEDVEN 225
Cdd:TIGR02917 104 GKFQQVLDE---LPGKTLLDDEgaAELLALRGLAYLGLGQLELAQKSYEQALAIDPRSLYAKLGLAQLALAENRFDEARA 180

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622846561 226 LGCRLFNISDQHAEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCR 305
Cdd:TIGR02917 181 LIDEVLTADPGNVDALLLKGDLLLSLGNIELALAAYRKAIALRPNNIAVLLALATILIEAGEFEEAEKHADALLKKAPNS 260

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622846561 306 LDC--YEGLIEcyLASNSIREAMvmaNNVYKTLGANAQTLT--LLATVCLEDPVTQEKAKTLLDKALTQRPDYIKAVVKK 381
Cdd:TIGR02917 261 PLAhyLKALVD--FQKKNYEDAR---ETLQDALKSAPEYLPalLLAGASEYQLGNLEQAYQYLNQILKYAPNSHQARRLL 335

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622846561 382 AELLSREQKYEDGIALLRNALA-NQSDCVLHRILGDFLVAVNEYQEAMDQYSIALSLDPND-----QKSLEGMQKMEKEE 455
Cdd:TIGR02917 336 ASIQLRLGRVDEAIATLSPALGlDPDDPAALSLLGEAYLALGDFEKAAEYLAKATELDPENaaartQLGISKLSQGDPSE 415

                         410
                  ....*....|...
gi 1622846561 456 SPTDATQEEDVDD 468
Cdd:TIGR02917 416 AIADLETAAQLDP 428
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 210-325 7.38e-09

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 54.43  E-value: 7.38e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622846561 210 YGYLLAREGRLEDVENLGCRLFNISDQHAEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQ 289
Cdd:COG4783    10 LAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYD 89

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 1622846561 290 EAIIHFREAIRLAPCRLDCYEGLIECYLASNSIREA 325
Cdd:COG4783    90 EALALLEKALKLDPEHPEAYLRLARAYRALGRPDEA 125
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 140-442 5.30e-08

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 55.47  E-value: 5.30e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622846561 140 KAYAFVHTGDNSRAINticSLEKK-SLLRDNVDLLGSLADLYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVYGYLLAREG 218
Cdd:TIGR02917 471 LGAIYLGKGDLAKARE---AFEKAlSIEPDFFPAAANLARIDIQEGNPDDAIQRFEKVLTIDPKNLRAILALAGLYLRTG 547

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622846561 219 RLEDVENLGCRLFNISDQHAEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREA 298
Cdd:TIGR02917 548 NEEEAVAWLEKAAELNPQEIEPALALAQYYLGKGQLKKALAILNEAADAAPDSPEAWLMLGRAQLAAGDLNKAVSSFKKL 627

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622846561 299 IRLAPcrldcyegliecylasnsireamvmannvyktlgANAQTLTLLATVCLEDPVTqEKAKTLLDKALTQRPDYIKAV 378
Cdd:TIGR02917 628 LALQP----------------------------------DSALALLLLADAYAVMKNY-AKAITSLKRALELKPDNTEAQ 672

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1622846561 379 VKKAELLSREQKYEDGIALLRN-ALANQSDCVLHRILGDFLVAVNEYQEAMDQYSIALSLDPNDQ 442
Cdd:TIGR02917 673 IGLAQLLLAAKRTESAKKIAKSlQKQHPKAALGFELEGDLYLRQKDYPAAIQAYRKALKRAPSSQ 737
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 176-303 5.97e-08

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 51.73  E-value: 5.97e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622846561 176 LADLYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVYGYLLAREGRLEDVENLGCRLFNISDQHAEPWVVSGCHSFYSKRYS 255
Cdd:COG4783    10 LAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYD 89

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 1622846561 256 RALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAP 303
Cdd:COG4783    90 EALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDP 137
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
339-448 1.19e-07

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 52.70  E-value: 1.19e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622846561 339 NAQTLTLLATVC--LEDPvtqEKAKTLLDKALTQRPDYIKAVVKKAELLSREQKYEDGIALLRNALANQSDCVLHRI-LG 415
Cdd:COG0457     7 DAEAYNNLGLAYrrLGRY---EEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNnLG 83

                          90       100       110
                  ....*....|....*....|....*....|...
gi 1622846561 416 DFLVAVNEYQEAMDQYSIALSLDPNDQKSLEGM 448
Cdd:COG0457    84 LALQALGRYEEALEDYDKALELDPDDAEALYNL 116
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 254-442 2.69e-07

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 53.16  E-value: 2.69e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622846561 254 YSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMVMANNVY 333
Cdd:TIGR02917 379 FEKAAEYLAKATELDPENAAARTQLGISKLSQGDPSEAIADLETAAQLDPELGRADLLLILSYLRSGQFDKALAAAKKLE 458

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622846561 334 KTLGANAQTLTLLATVCL--EDPvtqEKAKTLLDKALTQRPDYIKAVVKKAELLSREQKYEDGIALLRNALA-NQSDCVL 410
Cdd:TIGR02917 459 KKQPDNASLHNLLGAIYLgkGDL---AKAREAFEKALSIEPDFFPAAANLARIDIQEGNPDDAIQRFEKVLTiDPKNLRA 535

                         170       180       190
                  ....*....|....*....|....*....|..
gi 1622846561 411 HRILGDFLVAVNEYQEAMDQYSIALSLDPNDQ 442
Cdd:TIGR02917 536 ILALAGLYLRTGNEEEAVAWLEKAAELNPQEI 567
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 169-441 1.26e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 51.24  E-value: 1.26e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622846561 169 NVDLLGSLADLYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVYGYLLAREGRLEDVENLGCRLFNISDQHAEPWVVSGCHS 248
Cdd:TIGR02917 532 NLRAILALAGLYLRTGNEEEAVAWLEKAAELNPQEIEPALALAQYYLGKGQLKKALAILNEAADAAPDSPEAWLMLGRAQ 611

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622846561 249 FYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMVM 328
Cdd:TIGR02917 612 LAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKRALELKPDNTEAQIGLAQLLLAAKRTESAKKI 691

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622846561 329 ANNVYKTLGANAQTLTLLATVCLEDPVTQEkAKTLLDKALTQRPDYiKAVVKKAELLSREQKYEDGIALLRNALANQ-SD 407
Cdd:TIGR02917 692 AKSLQKQHPKAALGFELEGDLYLRQKDYPA-AIQAYRKALKRAPSS-QNAIKLHRALLASGNTAEAVKTLEAWLKTHpND 769

                         250       260       270
                  ....*....|....*....|....*....|....
gi 1622846561 408 CVLHRILGDFLVAVNEYQEAMDQYSIALSLDPND 441
Cdd:TIGR02917 770 AVLRTALAELYLAQKDYDKAIKHYQTVVKKAPDN 803
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
358-440 1.84e-06

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 46.32  E-value: 1.84e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622846561 358 EKAKTLLDKALTQRPDYIKAVVKKAELLSREQKYEDGIALLRNALANQSDCVLHRILGDFLVAVNEYQEAMDQYSIALSL 437
Cdd:COG3063     9 EEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIALEKALKLDPNNAEALLNLAELLLELGDYDEALAYLERALEL 88


                  ...
gi 1622846561 438 DPN 440
Cdd:COG3063    89 DPS 91
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 190-303 2.50e-06

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 46.92  E-value: 2.50e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622846561 190 VLKFEQAQMLDPYLIKGMDVYGYLLAREGRLEDVENLGCRLFNISDQHAEPWVVSGCHSFYSKRYSRALYLGAKAIQLNS 269
Cdd:COG4235     3 IARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDP 82

                          90       100       110
                  ....*....|....*....|....*....|....
gi 1622846561 270 NSVQALLLKGAALRNMGRVQEAIIHFREAIRLAP 303
Cdd:COG4235    83 DNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLP 116
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 359-445 2.55e-06

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 46.92  E-value: 2.55e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622846561 359 KAKTLLDKALTQRPDYIKAVVKKAELLSREQKYEDGIALLRNALA-NQSDCVLHRILGDFLVAVNEYQEAMDQYSIALSL 437
Cdd:COG4235     1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRlDPDNADALLDLAEALLAAGDTEEAEELLERALAL 80


                  ....*...
gi 1622846561 438 DPNDQKSL 445
Cdd:COG4235    81 DPDNPEAL 88
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 358-441 5.25e-06

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 45.77  E-value: 5.25e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622846561 358 EKAKTLLDKALTQRPDYIKAVVKKAELLSREQKYEDGIALLRNALANQSDCV-LHRILGDFLVAVNEYQEAMDQYSIALS 436
Cdd:COG4235    34 DEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPeALYLLGLAAFQQGDYAEAIAAWQKLLA 113


                  ....*
gi 1622846561 437 LDPND 441
Cdd:COG4235   114 LLPAD 118
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 32-325 1.27e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 48.16  E-value: 1.27e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622846561  32 PSEIEVKYKMAECYTMLKQDKDAIAILDGIPSRQR-TPKINMMLANLYKKAGQERPSVTSYKEVLRQCP---LALdAILG 107
Cdd:TIGR02917 564 PQEIEPALALAQYYLGKGQLKKALAILNEAADAAPdSPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPdsaLAL-LLLA 642

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622846561 108 LLSLSVKG-AEVASMTMNVIQTVPNLdWLSVWIKAYAFVHTGDNSRAINTICSLEKKSLLRDNVDLLgsLADLYFRAGDN 186
Cdd:TIGR02917 643 DAYAVMKNyAKAITSLKRALELKPDN-TEAQIGLAQLLLAAKRTESAKKIAKSLQKQHPKAALGFEL--EGDLYLRQKDY 719

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622846561 187 KNSVLKFEQAQMLDPYLIKGMDVYGYLLAR------EGRLEDV-----------------------ENLGCRLFNISDQH 237
Cdd:TIGR02917 720 PAAIQAYRKALKRAPSSQNAIKLHRALLASgntaeaVKTLEAWlkthpndavlrtalaelylaqkdYDKAIKHYQTVVKK 799

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622846561 238 AE--PWVVSGCHSFYSKRY-SRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIE 314
Cdd:TIGR02917 800 APdnAVVLNNLAWLYLELKdPRALEYAERALKLAPNIPAILDTLGWLLVEKGEADRALPLLRKAVNIAPEAAAIRYHLAL 879

                         330
                  ....*....|.
gi 1622846561 315 CYLASNSIREA 325
Cdd:TIGR02917 880 ALLATGRKAEA 890
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 195-325 2.03e-05

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 44.95  E-value: 2.03e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622846561 195 QAQMLDPYLIKGMDVYGYLLAREGRLEDVENLGCRLFNISDQHAEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQA 274
Cdd:COG5010    11 PLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPEL 90

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1622846561 275 LLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIREA 325
Cdd:COG5010    91 YYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEA 141
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 358-439 5.67e-05

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 43.41  E-value: 5.67e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622846561 358 EKAKTLLDKALTQRPDYIKAVVKKAELLSREQKYEDGIALLRNALA-NQSDCVLHRILGDFLVAVNEYQEAMDQYSIALS 436
Cdd:COG5010    71 EESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALAlSPDNPNAYSNLAALLLSLGQDDEAKAALQRALG 150


                  ...
gi 1622846561 437 LDP 439
Cdd:COG5010   151 TSP 153
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
179-303 1.21e-04

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 40.92  E-value: 1.21e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622846561 179 LYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVYGYLLAREGRLEDVENLgcrlfnisdqhaepwvvsgchsfyskrysral 258
Cdd:COG3063     1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIAL-------------------------------- 48

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 1622846561 259 ylgAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAP 303
Cdd:COG3063    49 ---EKALKLDPNNAEALLNLAELLLELGDYDEALAYLERALELDP 90
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 194-303 1.45e-04

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 42.25  E-value: 1.45e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622846561 194 EQAQMLDPYLIKGMDVYGYLLAREGRLEDVENLGCRLFNISDQHAEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQ 273
Cdd:COG5010    44 AAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPN 123

                          90       100       110
                  ....*....|....*....|....*....|
gi 1622846561 274 ALLLKGAALRNMGRVQEAIIHFREAIRLAP 303
Cdd:COG5010   124 AYSNLAALLLSLGQDDEAKAALQRALGTSP 153
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
245-368 3.70e-04

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 41.82  E-value: 3.70e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622846561 245 GCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCrlDCYEGLIECylasnsIRE 324
Cdd:COG4785   114 GLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLGRYELAIADLEKALELDPN--DPERALWLY------LAE 185

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 1622846561 325 AMVMANNVYKTLGANAQTLTLLatvcLEDPvtqEKAKTLLDKAL 368
Cdd:COG4785   186 RKLDPEKALALLLEDWATAYLL----QGDT---EEARELFKLAL 222
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 253-372 7.92e-04

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 39.94  E-value: 7.92e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622846561 253 RYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMVMANNV 332
Cdd:COG5010    35 NNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKA 114

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 1622846561 333 YKTLGANAQTLTLLATVcLEDPVTQEKAKTLLDKALTQRP 372
Cdd:COG5010   115 LALSPDNPNAYSNLAAL-LLSLGQDDEAKAALQRALGTSP 153
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 272-303 1.09e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 36.66  E-value: 1.09e-03
                           10        20        30
                   ....*....|....*....|....*....|..
gi 1622846561  272 VQALLLKGAALRNMGRVQEAIIHFREAIRLAP 303
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDP 32
TPR_2 pfam07719
Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats ...
 272-303 1.61e-03

Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats (TPR) that are not matched by pfam00515.


Pssm-ID: 429619 [Multi-domain]  Cd Length: 33  Bit Score: 35.96  E-value: 1.61e-03
                          10        20        30
                  ....*....|....*....|....*....|..
gi 1622846561 272 VQALLLKGAALRNMGRVQEAIIHFREAIRLAP 303
Cdd:pfam07719   1 AEALYNLGLAYYKLGDYEEALEAYEKALELDP 32
TPR_1 pfam00515
Tetratricopeptide repeat;
272-303 1.92e-03

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 35.86  E-value: 1.92e-03
                          10        20        30
                  ....*....|....*....|....*....|..
gi 1622846561 272 VQALLLKGAALRNMGRVQEAIIHFREAIRLAP 303
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELNP 32
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
281-373 4.07e-03

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 36.69  E-value: 4.07e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622846561 281 ALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMVMaNNVYKTLGANAQTLTLLATVCLEDPvTQEKA 360
Cdd:COG3063     1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIAL-EKALKLDPNNAEALLNLAELLLELG-DYDEA 78

                          90
                  ....*....|...
gi 1622846561 361 KTLLDKALTQRPD 373
Cdd:COG3063    79 LAYLERALELDPS 91
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
252-303 5.58e-03

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 38.36  E-value: 5.58e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1622846561 252 KRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAP 303
Cdd:COG4785    87 GDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDP 138
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 148-478 7.39e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 38.91  E-value: 7.39e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622846561 148 GDNSRAINTICSLEKKSllRDNVDLLGSLADLYFRAGDNKNSVLKFEQAQMLDP-----YLIKGMdvyGYLL---AREG- 218
Cdd:TIGR02917 343 GRVDEAIATLSPALGLD--PDDPAALSLLGEAYLALGDFEKAAEYLAKATELDPenaaaRTQLGI---SKLSqgdPSEAi 417

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622846561 219 -RLEDVENLGCRLfnisdQHAEPWVVSgcHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFRE 297
Cdd:TIGR02917 418 aDLETAAQLDPEL-----GRADLLLIL--SYLRSGQFDKALAAAKKLEKKQPDNASLHNLLGAIYLGKGDLAKAREAFEK 490

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622846561 298 AIRLAP---------CRLDCYEGLIEcylASNSIREAMVMAN-----------NVYKTLGANAQTLTLLATVCLEDPVTQ 357
Cdd:TIGR02917 491 ALSIEPdffpaaanlARIDIQEGNPD---DAIQRFEKVLTIDpknlrailalaGLYLRTGNEEEAVAWLEKAAELNPQEI 567

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622846561 358 EKAKTL---------LDKALTQRPDYIKAVVKKAE---LLSREQ----KYEDGIALLRNALANQSDCVL-HRILGDFLVA 420
Cdd:TIGR02917 568 EPALALaqyylgkgqLKKALAILNEAADAAPDSPEawlMLGRAQlaagDLNKAVSSFKKLLALQPDSALaLLLLADAYAV 647

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1622846561 421 VNEYQEAMDQYSIALSLDPNDQKSLEGMQKMEKEESPTDAT-------QEEDVDDMEGSGEEGDL 478
Cdd:TIGR02917 648 MKNYAKAITSLKRALELKPDNTEAQIGLAQLLLAAKRTESAkkiakslQKQHPKAALGFELEGDL 712
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
214-441 8.62e-03

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 37.97  E-value: 8.62e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622846561 214 LAREGRLEDVENLGCRLFNISDQHAEPWVVSGCHSFYSKRYSRALYLGAK-AIQLNSNSVQALLLKGAALRNMGRVQEAI 292
Cdd:COG4785    14 LAAAAASKAAILLAALLFAAVLALAIALADLALALAAAALAAAALAAERIdRALALPDLAQLYYERGVAYDSLGDYDLAI 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622846561 293 IHFREAIRLAPCRLDCYEGLIECYLASNSIREAmvmannvyktlganaqtltllatvcLEDpvtqekaktlLDKALTQRP 372
Cdd:COG4785    94 ADFDQALELDPDLAEAYNNRGLAYLLLGDYDAA-------------------------LED----------FDRALELDP 138

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1622846561 373 DYIKAvvkkaeLLSReqkyedGIALLRnalanqsdcvlhriLGDflvavneYQEAMDQYSIALSLDPND 441
Cdd:COG4785   139 DYAYA------YLNR------GIALYY--------------LGR-------YELAIADLEKALELDPND 174
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 32-226 9.23e-03

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 38.17  E-value: 9.23e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622846561  32 PSEIEVKYKMAECYTMLKQDKDAIAILD-GIPSRQRTPKINMMLANLYKKAGQERPSVTSYKEVLRQCPLALDAILGLls 110
Cdd:COG2956   107 PDDAEALRLLAEIYEQEGDWEKAIEVLErLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLL-- 184

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622846561 111 lsvkgaevasmtmnviqtvpnldwlsvwikAYAFVHTGDNSRAINTICSLEKKSllRDNVDLLGSLADLYFRAGDNKNSV 190
Cdd:COG2956   185 ------------------------------AELYLEQGDYEEAIAALERALEQD--PDYLPALPRLAELYEKLGDPEEAL 232

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 1622846561 191 LKFEQAQMLDPYLIKgMDVYGYLLAREGRLEDVENL 226
Cdd:COG2956   233 ELLRKALELDPSDDL-LLALADLLERKEGLEAALAL 267
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 165-222 9.35e-03

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 36.52  E-value: 9.35e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1622846561 165 LLRDNVDLLGSLADLYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVYGYLLAREGRLED 222
Cdd:COG4235    46 LDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLAAFQQGDYAE 103
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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