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presequence protease, mitochondrial isoform X5 [Macaca mulatta]
Protein Classification
insulinase family protein ( domain architecture ID 1002320 )
insulinase family protein (peptidase M16) is a zinc-dependent peptidase that cleaves small peptides close to a terminus, often including bonds on the amino side of basic residues such as arginine
List of domain hits
Name
Accession
Description
Interval
E-value
Cym1 super family
cl34067 Zn-dependent peptidase, M16 (insulinase) family [Posttranslational modification, protein ...
6-829
0e+00
Zn-dependent peptidase, M16 (insulinase) family [Posttranslational modification, protein turnover, chaperones];
COG1026 :Pssm-ID: 440649 [Multi-domain]
Cd Length: 974
Bit Score: 602.95
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622963945 6 G FLTDNERIFSQH LQ NR L L PD H TY SVV SGGDP LC IP E LT W EQ LKQ FH ATH YHPSNA RFFT YG NFPL E Q HL KQIH EE A LS K 85
Cdd:COG1026 168 G AMSSPDSVLWRA LQ KS L F PD T TY GYN SGGDP EV IP D LT Y EQ FLA FH KKY YHPSNA YIYL YG DIDA E E HL AFLD EE Y LS R 247
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622963945 86 F QKI E PSTT VP A Q TPWDK PRE FQI T -- CGPDS fat D PSKQ T TA S VSF LL PDI TD TF E AFT L S LLS SL L TSGPN SP FY KAL 163
Cdd:COG1026 248 F ERL E VDSE VP D Q KRFSA PRE VEE T yp VAEEE --- D TENK T YL S LNW LL GES TD LE E SLA L Q LLS YV L LGNSA SP LK KAL 324
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622963945 164 IE SGLG T D F S P dv G YNGYT R EAY FS V GL Q G IAEKDI E TVGS L VDR T IDEV VE K G FEDDRI EA L L HKI E IQMKHQSTS --- 240
Cdd:COG1026 325 LD SGLG K D V S G -- G LEDSL R QPV FS I GL K G SEPEKA E AFEK L ILE T LEKL VE E G IDKELL EA A L NQL E FSLREIDGG syp 402
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622963945 241 F GL M L TSYIASC W NHD GDP VE LL KLGNQ L A K F R QCLQ e N P KFLQEKVKQ Y FKN N Q H KLT L SMR PD DKYH E KQAQV E AT KL 320
Cdd:COG1026 403 Y GL Q L ILRALDS W LYG GDP LA LL RYEPA L E K L R EKIK - D P GYFENLIRK Y LLD N P H RVL L TLK PD PGLA E RKEAA E KE KL 481
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622963945 321 KQKVEA LS PGDR Q Q I Y E KGLE L RTQ Q SKPQDA --- SC LP A L KVS DI EPTIPVTE L GVVLTA G d I PV QYCAQP TNG M VY FR 397
Cdd:COG1026 482 AAIKAS LS EEEK Q A I I E QTKA L KER Q EQEDSP eal AT LP K L TLE DI PKEVKEIP L EEEELG G - V PV LFHDLF TNG I VY LD 560
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622963945 398 AFSS L NT LPEEL R PY V PL FCSV L TK LG C G LL DY RKQAQQ I ELK TGG M SAS PH V LPDDSHMDT Y EQGVLF S SLC L D RNL PD 477
Cdd:COG1026 561 LYFD L PA LPEEL L PY L PL LTDL L GE LG T G KY DY LELSNE I AAY TGG I SAS TS V YTNIDDVQE Y RPYFVV S GKA L A RNL DK 640
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622963945 478 MMH L WS EI FN N PC F EEEEHFKV LV KMTAQE L ANGIPD SGH LY A SI RA GRTLT PA GDLQ E TF SG MDQV R LM K RIA E M -- TD 555
Cdd:COG1026 641 LFE L LK EI LL N TR F DDKKRLRE LV AQIKAR L EQSLTG SGH SL A MS RA SSYFS PA AAYS E QL SG LSYY R FL K DLE E N ld EK 720
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622963945 556 IKPILR KL PRIKKH L L N GD N MRC SV NATPQQMSQTE K VV E D F LR S IGRSKKERR pvrphtvekpvpsssggdahvlhgsq 635
Cdd:COG1026 721 LEELAE KL QELADK L F N RP N LLI SV TGEEEELEAFK K AL E A F IA S LPAGTAAPF -------------------------- 774
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622963945 636 iirklvm EPT F KPWQMKTHFLMPFP VNYV GECIRT VP YTDPDHAS L KI LA RLMTAKF L HTE IR E --------- KGG aygg 706
Cdd:COG1026 775 ------- KYP F DAEPKNEGWITSSQ VNYV AKAYNF VP LGHEYAGA L LV LA GILRNGY L WNK IR V qggayggga SFD ---- 843
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622963945 707 gakl S H SG V F TL YSYRDPN TI ETL QSFGK A V DW AKSGKFTQQDIDE A KLSVF S TV D A P VA P SD KG MDH F --- L Y G LSD E M 783
Cdd:COG1026 844 ---- S L SG N F RF YSYRDPN LK ETL DVYDE A P DW LRNFDLSERELEK A IIGTI S SL D K P LS P AG KG KRA F hry L S G RTP E D 919
810 820 830 840
....*....|....*....|....*....|....*....|....*.
gi 1622963945 784 K Q AH R EQLFAVSHDK L LA V SDR YL GTG K STH g L A IL G P E N p KI AKD 829
Cdd:COG1026 920 R Q KF R DEILSTTLED L RR V AEL YL DVL K EAS - I A VI G N E E - KI EEA 963
Name
Accession
Description
Interval
E-value
Cym1
COG1026 Zn-dependent peptidase, M16 (insulinase) family [Posttranslational modification, protein ...
6-829
0e+00
Zn-dependent peptidase, M16 (insulinase) family [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440649 [Multi-domain]
Cd Length: 974
Bit Score: 602.95
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622963945 6 G FLTDNERIFSQH LQ NR L L PD H TY SVV SGGDP LC IP E LT W EQ LKQ FH ATH YHPSNA RFFT YG NFPL E Q HL KQIH EE A LS K 85
Cdd:COG1026 168 G AMSSPDSVLWRA LQ KS L F PD T TY GYN SGGDP EV IP D LT Y EQ FLA FH KKY YHPSNA YIYL YG DIDA E E HL AFLD EE Y LS R 247
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622963945 86 F QKI E PSTT VP A Q TPWDK PRE FQI T -- CGPDS fat D PSKQ T TA S VSF LL PDI TD TF E AFT L S LLS SL L TSGPN SP FY KAL 163
Cdd:COG1026 248 F ERL E VDSE VP D Q KRFSA PRE VEE T yp VAEEE --- D TENK T YL S LNW LL GES TD LE E SLA L Q LLS YV L LGNSA SP LK KAL 324
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622963945 164 IE SGLG T D F S P dv G YNGYT R EAY FS V GL Q G IAEKDI E TVGS L VDR T IDEV VE K G FEDDRI EA L L HKI E IQMKHQSTS --- 240
Cdd:COG1026 325 LD SGLG K D V S G -- G LEDSL R QPV FS I GL K G SEPEKA E AFEK L ILE T LEKL VE E G IDKELL EA A L NQL E FSLREIDGG syp 402
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622963945 241 F GL M L TSYIASC W NHD GDP VE LL KLGNQ L A K F R QCLQ e N P KFLQEKVKQ Y FKN N Q H KLT L SMR PD DKYH E KQAQV E AT KL 320
Cdd:COG1026 403 Y GL Q L ILRALDS W LYG GDP LA LL RYEPA L E K L R EKIK - D P GYFENLIRK Y LLD N P H RVL L TLK PD PGLA E RKEAA E KE KL 481
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622963945 321 KQKVEA LS PGDR Q Q I Y E KGLE L RTQ Q SKPQDA --- SC LP A L KVS DI EPTIPVTE L GVVLTA G d I PV QYCAQP TNG M VY FR 397
Cdd:COG1026 482 AAIKAS LS EEEK Q A I I E QTKA L KER Q EQEDSP eal AT LP K L TLE DI PKEVKEIP L EEEELG G - V PV LFHDLF TNG I VY LD 560
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622963945 398 AFSS L NT LPEEL R PY V PL FCSV L TK LG C G LL DY RKQAQQ I ELK TGG M SAS PH V LPDDSHMDT Y EQGVLF S SLC L D RNL PD 477
Cdd:COG1026 561 LYFD L PA LPEEL L PY L PL LTDL L GE LG T G KY DY LELSNE I AAY TGG I SAS TS V YTNIDDVQE Y RPYFVV S GKA L A RNL DK 640
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622963945 478 MMH L WS EI FN N PC F EEEEHFKV LV KMTAQE L ANGIPD SGH LY A SI RA GRTLT PA GDLQ E TF SG MDQV R LM K RIA E M -- TD 555
Cdd:COG1026 641 LFE L LK EI LL N TR F DDKKRLRE LV AQIKAR L EQSLTG SGH SL A MS RA SSYFS PA AAYS E QL SG LSYY R FL K DLE E N ld EK 720
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622963945 556 IKPILR KL PRIKKH L L N GD N MRC SV NATPQQMSQTE K VV E D F LR S IGRSKKERR pvrphtvekpvpsssggdahvlhgsq 635
Cdd:COG1026 721 LEELAE KL QELADK L F N RP N LLI SV TGEEEELEAFK K AL E A F IA S LPAGTAAPF -------------------------- 774
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622963945 636 iirklvm EPT F KPWQMKTHFLMPFP VNYV GECIRT VP YTDPDHAS L KI LA RLMTAKF L HTE IR E --------- KGG aygg 706
Cdd:COG1026 775 ------- KYP F DAEPKNEGWITSSQ VNYV AKAYNF VP LGHEYAGA L LV LA GILRNGY L WNK IR V qggayggga SFD ---- 843
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622963945 707 gakl S H SG V F TL YSYRDPN TI ETL QSFGK A V DW AKSGKFTQQDIDE A KLSVF S TV D A P VA P SD KG MDH F --- L Y G LSD E M 783
Cdd:COG1026 844 ---- S L SG N F RF YSYRDPN LK ETL DVYDE A P DW LRNFDLSERELEK A IIGTI S SL D K P LS P AG KG KRA F hry L S G RTP E D 919
810 820 830 840
....*....|....*....|....*....|....*....|....*.
gi 1622963945 784 K Q AH R EQLFAVSHDK L LA V SDR YL GTG K STH g L A IL G P E N p KI AKD 829
Cdd:COG1026 920 R Q KF R DEILSTTLED L RR V AEL YL DVL K EAS - I A VI G N E E - KI EEA 963
M16C_assoc
pfam08367 Peptidase M16C associated; This domain appears in eukaryotes as well as bacteria and tends to ...
302-550
2.34e-104
Peptidase M16C associated; This domain appears in eukaryotes as well as bacteria and tends to be found near the C-terminus of the metalloprotease M16C (pfam05193).
Pssm-ID: 462447 [Multi-domain]
Cd Length: 248
Bit Score: 321.78
E-value: 2.34e-104
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622963945 302 M R PD DKYH E KQAQV E ATK L KQ K VEA LS PGDRQQ I Y E KG LEL RTQ Q SK P -- Q D A SCLP A L KV SDI EPT I P V TE lgv VLTA G 379
Cdd:pfam08367 1 M K PD EGLS E ELEEE E KER L AA K KAS LS EEEKEK I V E RT LEL KER Q EA P ds E D L SCLP T L TL SDI PRE I E V EP --- EEEI G 77
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622963945 380 DI PV QYCAQ PTNG M VYFRA FSS L NT LPEEL R PY V PLF C SVLT K LG CGLL DY RKQA Q Q I E LKTGG M SASP H V LP D DSHM D T 459
Cdd:pfam08367 78 GV PV LHHDV PTNG I VYFRA IFD L SD LPEEL L PY L PLF T SVLT E LG TKKY DY EELE Q E I N LKTGG I SASP S V SS D PDDL D K 157
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622963945 460 YE Q G VLF S SLC LDRN L P D M MH L WS EI FNNPC F EEE E HF K V LV KMTAQE L A N G I PD SGH L YA SI RA GRT L T PAG D L Q E TF S 539
Cdd:pfam08367 158 YE P G FVV S GKA LDRN V P K M FD L LR EI LLETK F DDK E RL K E LV QESKSR L E N S I AS SGH S YA MS RA ASY L S PAG A L S E QL S 237
250
....*....|.
gi 1622963945 540 G MD Q VRLM K RI 550
Cdd:pfam08367 238 G LS Q YKFL K DL 248
PTZ00432
PTZ00432 falcilysin; Provisional
15-791
2.34e-52
falcilysin; Provisional
Pssm-ID: 240416 [Multi-domain]
Cd Length: 1119
Bit Score: 198.10
E-value: 2.34e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622963945 15 F SQHLQNRL L PDHT Y SVV SGGDP LC I P ELT W E Q L KQ F HA T H Y H P SN A RFFT YG -------- N F p LEQH L KQIHEEALSKF 86
Cdd:PTZ00432 259 F GYSVIYQN L FSNV Y KYD SGGDP KD I V ELT Y E E L VE F YK T Y Y G P KT A TVYF YG pndvterl E F - VDNY L TKHPKTGQLSH 337
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622963945 87 QKIEPS -- TTVPAQTPW DKP R ---- E F Q i TCGPD ------- S FATD P SKQTTASVSFL L P D IT D tfe AFT L SL L SS LL TS 153
Cdd:PTZ00432 338 TAYRED ad ENLLYEEYK DKP K hvkk K F S - SHSEE eenlmsv S WLLN P KHNGSKDYDKS L I D PV D --- YLA L LV L NY LL LG 413
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622963945 154 G P N S PF YKALI E SGLG TDFS p DV G YNG Y TREAY FS V GL Q GI A E KD ------- IE T VGSL V DRTIDE VV EK GF EDDRI EA L 226
Cdd:PTZ00432 414 T P E S VL YKALI D SGLG KKVV - GS G LDD Y FKQSI FS I GL K GI K E TN ekrkdkv HY T FEKV V LNALTK VV TE GF NKSAV EA S 492
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622963945 227 L HK IE IQ MK - HQSTSF -- GLML TSYIA S CWNHDG DP V E L L KLGNQ L AKFRQCLQENP K F L QEKVKQYFK NN Q H KL T LSMR 303
Cdd:PTZ00432 493 L NN IE FV MK e LNLGTY pk GLML IFLMQ S RLQYGK DP F E I L RFEKL L NELKLRIDNES K Y L EKLIEKHLL NN N H RV T VHLE 572
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622963945 304 PDD -- KY HEKQAQVEATK LK QKVEA L SPGDRQQI --- YEK GLEL R TQQSK P QDASCL P A L KV SD IEP --- T IP VT ----- 370
Cdd:PTZ00432 573 AVE ss KY EKEFNKLVKDE LK ERLSH L TKEQVDEM eka YEK FKKE R EADDD P EHLDSF P I L SL SD LNK ete E IP TK lykls 652
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622963945 371 ---- ELGVV L TA -- G DIP V QYCAQPTN G MV Y FRAFS SL NT L P - E EL R p Y VP LF CSV L TKL G CGL L DYRKQAQQI E LKT GG 443
Cdd:PTZ00432 653 sdsl KENMD L DS dg G SVT V LVHPIESR G IL Y LDFAF SL DS L T v D EL K - Y LN LF KAL L KEN G TDK L SSEEFTYKR E KNL GG 731
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622963945 444 M SAS PHVLPDDSHM --- D T Y E - Q G V L - FSSLC L DRNLPD M MHLWS E IFNNPC F EEEEHFKVLV K MTAQELANGIPDS GH L 518
Cdd:PTZ00432 732 L SAS TAFYSETNNL tyd D P Y N g V G Y L n VRAKV L KHKVNE M VDIVL E ALKDAD F SNSKKGVEIL K RKINGMKTVFSSK GH K 811
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622963945 519 Y A SI R AGRTLTPAGDLQ E TFS G MD Q VRLM K ---- RI AE m T D IKPILR KL PR I KKH LL NGD N MRCS V NATPQQMSQ tek VV 594
Cdd:PTZ00432 812 F A LK R MKSKFSVSDYAD E LVN G YS Q LLFL K etlv PL AE - K D WSKVES KL NE I RNK LL SMK N LTVN V TGDSELLDS --- LL 887
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622963945 595 E D --- FL RSIGRSK KE rrpvrphtvekpvps SSGGDAHVLHGSQIIR K LV ME PTF K pwqm KTHFLM P FP VN Y VG ECIRTV 671
Cdd:PTZ00432 888 D D stt FL KKLSSTF KE --------------- NDNKSSDKVWVKEVLD K KL ME SVD K ---- NEFIVL P TR VN F VG MGGKLF 948
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622963945 672 PYT D PDHA S LKILARLMTAKF L HTEI R EKG GAYG GG A K L SHS G VFTLY SY R DPN TIE TL QSFGKAVDWAKSG -- KF T QQ D 749
Cdd:PTZ00432 949 DKS D KVDG S FQVIVHYLKNSY L WKTV R MSL GAYG VF A D L LYT G HVIFM SY A DPN FEK TL EVYKEVASALREA ae TL T DK D 1028
810 820 830 840
....*....|....*....|....*....|....*....|....*
gi 1622963945 750 IDEA K LSVF S TV D A P VAPSDKGMDHF --- LYGL SDE MK Q AH R EQL 791
Cdd:PTZ00432 1029 LLRY K IGKI S NI D K P LHVDELSKLAL lri IRNE SDE DR Q KF R KDI 1073
Name
Accession
Description
Interval
E-value
Cym1
COG1026 Zn-dependent peptidase, M16 (insulinase) family [Posttranslational modification, protein ...
6-829
0e+00
Zn-dependent peptidase, M16 (insulinase) family [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440649 [Multi-domain]
Cd Length: 974
Bit Score: 602.95
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622963945 6 G FLTDNERIFSQH LQ NR L L PD H TY SVV SGGDP LC IP E LT W EQ LKQ FH ATH YHPSNA RFFT YG NFPL E Q HL KQIH EE A LS K 85
Cdd:COG1026 168 G AMSSPDSVLWRA LQ KS L F PD T TY GYN SGGDP EV IP D LT Y EQ FLA FH KKY YHPSNA YIYL YG DIDA E E HL AFLD EE Y LS R 247
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622963945 86 F QKI E PSTT VP A Q TPWDK PRE FQI T -- CGPDS fat D PSKQ T TA S VSF LL PDI TD TF E AFT L S LLS SL L TSGPN SP FY KAL 163
Cdd:COG1026 248 F ERL E VDSE VP D Q KRFSA PRE VEE T yp VAEEE --- D TENK T YL S LNW LL GES TD LE E SLA L Q LLS YV L LGNSA SP LK KAL 324
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622963945 164 IE SGLG T D F S P dv G YNGYT R EAY FS V GL Q G IAEKDI E TVGS L VDR T IDEV VE K G FEDDRI EA L L HKI E IQMKHQSTS --- 240
Cdd:COG1026 325 LD SGLG K D V S G -- G LEDSL R QPV FS I GL K G SEPEKA E AFEK L ILE T LEKL VE E G IDKELL EA A L NQL E FSLREIDGG syp 402
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622963945 241 F GL M L TSYIASC W NHD GDP VE LL KLGNQ L A K F R QCLQ e N P KFLQEKVKQ Y FKN N Q H KLT L SMR PD DKYH E KQAQV E AT KL 320
Cdd:COG1026 403 Y GL Q L ILRALDS W LYG GDP LA LL RYEPA L E K L R EKIK - D P GYFENLIRK Y LLD N P H RVL L TLK PD PGLA E RKEAA E KE KL 481
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622963945 321 KQKVEA LS PGDR Q Q I Y E KGLE L RTQ Q SKPQDA --- SC LP A L KVS DI EPTIPVTE L GVVLTA G d I PV QYCAQP TNG M VY FR 397
Cdd:COG1026 482 AAIKAS LS EEEK Q A I I E QTKA L KER Q EQEDSP eal AT LP K L TLE DI PKEVKEIP L EEEELG G - V PV LFHDLF TNG I VY LD 560
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622963945 398 AFSS L NT LPEEL R PY V PL FCSV L TK LG C G LL DY RKQAQQ I ELK TGG M SAS PH V LPDDSHMDT Y EQGVLF S SLC L D RNL PD 477
Cdd:COG1026 561 LYFD L PA LPEEL L PY L PL LTDL L GE LG T G KY DY LELSNE I AAY TGG I SAS TS V YTNIDDVQE Y RPYFVV S GKA L A RNL DK 640
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622963945 478 MMH L WS EI FN N PC F EEEEHFKV LV KMTAQE L ANGIPD SGH LY A SI RA GRTLT PA GDLQ E TF SG MDQV R LM K RIA E M -- TD 555
Cdd:COG1026 641 LFE L LK EI LL N TR F DDKKRLRE LV AQIKAR L EQSLTG SGH SL A MS RA SSYFS PA AAYS E QL SG LSYY R FL K DLE E N ld EK 720
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622963945 556 IKPILR KL PRIKKH L L N GD N MRC SV NATPQQMSQTE K VV E D F LR S IGRSKKERR pvrphtvekpvpsssggdahvlhgsq 635
Cdd:COG1026 721 LEELAE KL QELADK L F N RP N LLI SV TGEEEELEAFK K AL E A F IA S LPAGTAAPF -------------------------- 774
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622963945 636 iirklvm EPT F KPWQMKTHFLMPFP VNYV GECIRT VP YTDPDHAS L KI LA RLMTAKF L HTE IR E --------- KGG aygg 706
Cdd:COG1026 775 ------- KYP F DAEPKNEGWITSSQ VNYV AKAYNF VP LGHEYAGA L LV LA GILRNGY L WNK IR V qggayggga SFD ---- 843
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622963945 707 gakl S H SG V F TL YSYRDPN TI ETL QSFGK A V DW AKSGKFTQQDIDE A KLSVF S TV D A P VA P SD KG MDH F --- L Y G LSD E M 783
Cdd:COG1026 844 ---- S L SG N F RF YSYRDPN LK ETL DVYDE A P DW LRNFDLSERELEK A IIGTI S SL D K P LS P AG KG KRA F hry L S G RTP E D 919
810 820 830 840
....*....|....*....|....*....|....*....|....*.
gi 1622963945 784 K Q AH R EQLFAVSHDK L LA V SDR YL GTG K STH g L A IL G P E N p KI AKD 829
Cdd:COG1026 920 R Q KF R DEILSTTLED L RR V AEL YL DVL K EAS - I A VI G N E E - KI EEA 963
M16C_assoc
pfam08367 Peptidase M16C associated; This domain appears in eukaryotes as well as bacteria and tends to ...
302-550
2.34e-104
Peptidase M16C associated; This domain appears in eukaryotes as well as bacteria and tends to be found near the C-terminus of the metalloprotease M16C (pfam05193).
Pssm-ID: 462447 [Multi-domain]
Cd Length: 248
Bit Score: 321.78
E-value: 2.34e-104
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622963945 302 M R PD DKYH E KQAQV E ATK L KQ K VEA LS PGDRQQ I Y E KG LEL RTQ Q SK P -- Q D A SCLP A L KV SDI EPT I P V TE lgv VLTA G 379
Cdd:pfam08367 1 M K PD EGLS E ELEEE E KER L AA K KAS LS EEEKEK I V E RT LEL KER Q EA P ds E D L SCLP T L TL SDI PRE I E V EP --- EEEI G 77
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622963945 380 DI PV QYCAQ PTNG M VYFRA FSS L NT LPEEL R PY V PLF C SVLT K LG CGLL DY RKQA Q Q I E LKTGG M SASP H V LP D DSHM D T 459
Cdd:pfam08367 78 GV PV LHHDV PTNG I VYFRA IFD L SD LPEEL L PY L PLF T SVLT E LG TKKY DY EELE Q E I N LKTGG I SASP S V SS D PDDL D K 157
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622963945 460 YE Q G VLF S SLC LDRN L P D M MH L WS EI FNNPC F EEE E HF K V LV KMTAQE L A N G I PD SGH L YA SI RA GRT L T PAG D L Q E TF S 539
Cdd:pfam08367 158 YE P G FVV S GKA LDRN V P K M FD L LR EI LLETK F DDK E RL K E LV QESKSR L E N S I AS SGH S YA MS RA ASY L S PAG A L S E QL S 237
250
....*....|.
gi 1622963945 540 G MD Q VRLM K RI 550
Cdd:pfam08367 238 G LS Q YKFL K DL 248
PTZ00432
PTZ00432 falcilysin; Provisional
15-791
2.34e-52
falcilysin; Provisional
Pssm-ID: 240416 [Multi-domain]
Cd Length: 1119
Bit Score: 198.10
E-value: 2.34e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622963945 15 F SQHLQNRL L PDHT Y SVV SGGDP LC I P ELT W E Q L KQ F HA T H Y H P SN A RFFT YG -------- N F p LEQH L KQIHEEALSKF 86
Cdd:PTZ00432 259 F GYSVIYQN L FSNV Y KYD SGGDP KD I V ELT Y E E L VE F YK T Y Y G P KT A TVYF YG pndvterl E F - VDNY L TKHPKTGQLSH 337
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622963945 87 QKIEPS -- TTVPAQTPW DKP R ---- E F Q i TCGPD ------- S FATD P SKQTTASVSFL L P D IT D tfe AFT L SL L SS LL TS 153
Cdd:PTZ00432 338 TAYRED ad ENLLYEEYK DKP K hvkk K F S - SHSEE eenlmsv S WLLN P KHNGSKDYDKS L I D PV D --- YLA L LV L NY LL LG 413
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622963945 154 G P N S PF YKALI E SGLG TDFS p DV G YNG Y TREAY FS V GL Q GI A E KD ------- IE T VGSL V DRTIDE VV EK GF EDDRI EA L 226
Cdd:PTZ00432 414 T P E S VL YKALI D SGLG KKVV - GS G LDD Y FKQSI FS I GL K GI K E TN ekrkdkv HY T FEKV V LNALTK VV TE GF NKSAV EA S 492
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622963945 227 L HK IE IQ MK - HQSTSF -- GLML TSYIA S CWNHDG DP V E L L KLGNQ L AKFRQCLQENP K F L QEKVKQYFK NN Q H KL T LSMR 303
Cdd:PTZ00432 493 L NN IE FV MK e LNLGTY pk GLML IFLMQ S RLQYGK DP F E I L RFEKL L NELKLRIDNES K Y L EKLIEKHLL NN N H RV T VHLE 572
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622963945 304 PDD -- KY HEKQAQVEATK LK QKVEA L SPGDRQQI --- YEK GLEL R TQQSK P QDASCL P A L KV SD IEP --- T IP VT ----- 370
Cdd:PTZ00432 573 AVE ss KY EKEFNKLVKDE LK ERLSH L TKEQVDEM eka YEK FKKE R EADDD P EHLDSF P I L SL SD LNK ete E IP TK lykls 652
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622963945 371 ---- ELGVV L TA -- G DIP V QYCAQPTN G MV Y FRAFS SL NT L P - E EL R p Y VP LF CSV L TKL G CGL L DYRKQAQQI E LKT GG 443
Cdd:PTZ00432 653 sdsl KENMD L DS dg G SVT V LVHPIESR G IL Y LDFAF SL DS L T v D EL K - Y LN LF KAL L KEN G TDK L SSEEFTYKR E KNL GG 731
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622963945 444 M SAS PHVLPDDSHM --- D T Y E - Q G V L - FSSLC L DRNLPD M MHLWS E IFNNPC F EEEEHFKVLV K MTAQELANGIPDS GH L 518
Cdd:PTZ00432 732 L SAS TAFYSETNNL tyd D P Y N g V G Y L n VRAKV L KHKVNE M VDIVL E ALKDAD F SNSKKGVEIL K RKINGMKTVFSSK GH K 811
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622963945 519 Y A SI R AGRTLTPAGDLQ E TFS G MD Q VRLM K ---- RI AE m T D IKPILR KL PR I KKH LL NGD N MRCS V NATPQQMSQ tek VV 594
Cdd:PTZ00432 812 F A LK R MKSKFSVSDYAD E LVN G YS Q LLFL K etlv PL AE - K D WSKVES KL NE I RNK LL SMK N LTVN V TGDSELLDS --- LL 887
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622963945 595 E D --- FL RSIGRSK KE rrpvrphtvekpvps SSGGDAHVLHGSQIIR K LV ME PTF K pwqm KTHFLM P FP VN Y VG ECIRTV 671
Cdd:PTZ00432 888 D D stt FL KKLSSTF KE --------------- NDNKSSDKVWVKEVLD K KL ME SVD K ---- NEFIVL P TR VN F VG MGGKLF 948
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622963945 672 PYT D PDHA S LKILARLMTAKF L HTEI R EKG GAYG GG A K L SHS G VFTLY SY R DPN TIE TL QSFGKAVDWAKSG -- KF T QQ D 749
Cdd:PTZ00432 949 DKS D KVDG S FQVIVHYLKNSY L WKTV R MSL GAYG VF A D L LYT G HVIFM SY A DPN FEK TL EVYKEVASALREA ae TL T DK D 1028
810 820 830 840
....*....|....*....|....*....|....*....|....*
gi 1622963945 750 IDEA K LSVF S TV D A P VAPSDKGMDHF --- LYGL SDE MK Q AH R EQL 791
Cdd:PTZ00432 1029 LLRY K IGKI S NI D K P LHVDELSKLAL lri IRNE SDE DR Q KF R KDI 1073
Peptidase_M16_C
pfam05193 Peptidase M16 inactive domain; Peptidase M16 consists of two structurally related domains. One ...
43-230
7.63e-19
Peptidase M16 inactive domain; Peptidase M16 consists of two structurally related domains. One is the active peptidase, whereas the other is inactive. The two domains hold the substrate like a clamp.
Pssm-ID: 428362 [Multi-domain]
Cd Length: 181
Bit Score: 85.14
E-value: 7.63e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622963945 43 LT W E Q L KQ F HAT HY H P S N ARFFTY G NFPL E QH L KQI h E EALSKFQK iepstt V P AQT P WDK P R E FQITC G PDSF - ATDPS 121
Cdd:pfam05193 2 LT R E D L RD F YKK HY S P D N MVLVIV G DVDH E EL L DLA - E KYFGDLPA ------ S P KGK P RPP P L E PAKLK G REVV v PKKDE 74
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622963945 122 K Q TTASVS F LL P DITDTFEAFT L SL L SS LL TS G PN S PFYKA L I E - S GL GTDF S P dv GYNG Y TREAY F SVGLQGIA E K d IE 200
Cdd:pfam05193 75 P Q AHLALA F PG P PLNNDEDSLA L DV L NE LL GG G MS S RLFQE L R E k E GL AYSV S S -- FNDS Y SDSGL F GIYATVDP E N - VD 151
170 180 190
....*....|....*....|....*....|
gi 1622963945 201 T V GS L VDRTIDEVVEK G FEDDRI E ALLHKI 230
Cdd:pfam05193 152 E V IE L ILEELEKLAQE G VTEEEL E RAKNQL 181
PqqL
COG0612 Predicted Zn-dependent peptidase, M16 family [General function prediction only];
8-307
1.60e-16
Predicted Zn-dependent peptidase, M16 family [General function prediction only];
Pssm-ID: 440377 [Multi-domain]
Cd Length: 427
Bit Score: 82.66
E-value: 1.60e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622963945 8 LT D NERIFSQH L QNR L LP DH T Y SVVSG G DPLC I PEL T W E Q L KQ F HATH Y H P S NA RFFTY G NFPL E QH L KQI h E EALSKFQ 87
Cdd:COG0612 144 ED D PDGLAFEA L LAA L YG DH P Y GRPII G TEES I EAI T R E D L RA F YKRY Y R P N NA VLVVV G DVDP E EV L ALV - E KYFGDLP 222
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622963945 88 KIE - P STTV PA QT P WDK PR EFQIT cgpdsfa TDPSK Q TTASVSFLL P DIT D T f EAFT L SL L SSL L TS G PN S PFYKA L I E S 166
Cdd:COG0612 223 AGP a P PRPD PA EP P QTG PR RVVVD ------- DPDAE Q AHILLGYPG P ARD D P - DYYA L DV L NEI L GG G FS S RLFQE L R E K 294
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622963945 167 GLGTD f S PDVGYNG Y TREAY F SVGL q G I A EKDI E TVGSLVDRTIDEVVEK G FEDDRI E ALLHKIEIQM - KHQSTSF GL M l 245
Cdd:COG0612 295 KGLAY - S VGSSFSP Y RDAGL F TIYA - G T A PDKL E EALAAILEELERLAKE G VTEEEL E RAKNQLLGSL a LSLESNS GL A - 371
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1622963945 246 t S YIASCWNHD GD P vellklg NQ L AKFRQCLQE - NPKFL Q EKVKQ Y FKNNQH k LTLSMR P DD K 307
Cdd:COG0612 372 - S QLGRYELYG GD L ------- DY L EEYLERIEA v TAEDV Q AVARK Y LDPDNL - VVVVVG P KK K 425
Peptidase_M16_C
pfam05193 Peptidase M16 inactive domain; Peptidase M16 consists of two structurally related domains. One ...
566-754
5.74e-05
Peptidase M16 inactive domain; Peptidase M16 consists of two structurally related domains. One is the active peptidase, whereas the other is inactive. The two domains hold the substrate like a clamp.
Pssm-ID: 428362 [Multi-domain]
Cd Length: 181
Bit Score: 44.69
E-value: 5.74e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622963945 566 I KKH L l NG DNM RCSV -- NATPQQM sqt EKVV E DFLRSIGR S K K ERRPVR P HTVE K pvpsssggdahv L H G SQIIRKLVM E 643
Cdd:pfam05193 11 Y KKH Y - SP DNM VLVI vg DVDHEEL --- LDLA E KYFGDLPA S P K GKPRPP P LEPA K ------------ L K G REVVVPKKD E 74
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622963945 644 P T fkpwqmk T H FLMP FP VNY vgecirtv PYT D P D HAS L KI L AR L MTAKF --- L HT E I REK G G A ---- YGGGAKL S H SG V F 716
Cdd:pfam05193 75 P Q ------- A H LALA FP GPP -------- LNN D E D SLA L DV L NE L LGGGM ssr L FQ E L REK E G L aysv SSFNDSY S D SG L F 139
170 180 190
....*....|....*....|....*....|....*....
gi 1622963945 717 TL Y SYR DP NTI - E TLQSFGKAVDWAKSGKF T QQDIDE AK 754
Cdd:pfam05193 140 GI Y ATV DP ENV d E VIELILEELEKLAQEGV T EEELER AK 178
PqqL
COG0612 Predicted Zn-dependent peptidase, M16 family [General function prediction only];
459-825
3.33e-04
Predicted Zn-dependent peptidase, M16 family [General function prediction only];
Pssm-ID: 440377 [Multi-domain]
Cd Length: 427
Bit Score: 44.14
E-value: 3.33e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622963945 459 TYEQG V LFS S l C L DRN L PDMMH L WSEIFN NP C F E EEE h FKVLVKMTAQ E LANGI -- PD S ------- GH LY ASIRA GR T lt 529
Cdd:COG0612 93 SFDYT V YYL S - V L SED L ELALE L LADRLL NP T F D EEE - LERERGVVLE E IRRYE dd PD G lafeall AA LY GDHPY GR P -- 168
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622963945 530 PA G DLQE tfsgmdqvrlmkr I AEM T -- D IK pilrklp RIK K HLLNGD N MRCS V -- NAT P QQM sqt EKV VE DFLRSI grs K 605
Cdd:COG0612 169 II G TEES ------------- I EAI T re D LR ------- AFY K RYYRPN N AVLV V vg DVD P EEV --- LAL VE KYFGDL --- P 222
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622963945 606 KERR P V RP HTV E K P VP sssggdahvlhgs QII R KL V ME P TFK pwqm KT H F L MPF P vnyvgecir TVPYT DPD HAS L KI L A 685
Cdd:COG0612 223 AGPA P P RP DPA E P P QT ------------- GPR R VV V DD P DAE ---- QA H I L LGY P --------- GPARD DPD YYA L DV L N 276
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622963945 686 RLMTAK F --- L HT E I REK G G A ---- YGGGAKLSHS G V FT L Y - SYRDPNTI E T L QSFGKAVDWAKSGKF T QQDIDE AK LSV 757
Cdd:COG0612 277 EILGGG F ssr L FQ E L REK K G L aysv GSSFSPYRDA G L FT I Y a GTAPDKLE E A L AAILEELERLAKEGV T EEELER AK NQL 356
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1622963945 758 fs TVDAPVA --- P S DKGM --- DHF LYG LSDEMKQAHR E QLF AV SHDKLL AV SDR YL GTGKST hg LAIL GP ENPK 825
Cdd:COG0612 357 -- LGSLALS les N S GLAS qlg RYE LYG GDLDYLEEYL E RIE AV TAEDVQ AV ARK YL DPDNLV -- VVVV GP KKKA 426
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
