|
Name |
Accession |
Description |
Interval |
E-value |
| Cast |
pfam10174 |
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ... |
150-923 |
0e+00 |
|
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.
Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 1230.84 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 150 LQAQLKELQRENDLLRKELDIKDSKLGSSMNSIKTFWSPELKKERVLRKEEAARMSVLKEQMRVSHEENQHLQLTIQALQ 229
Cdd:pfam10174 1 LQAQLRDLQRENELLRRELDIKESKLGSSMNSIKTFWSPELKKERALRKEEAARISVLKEQYRVTQEENQHLQLTIQALQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 230 DELRTQRDLNHLLQQE---SGNRGAEHF-TIELTEENFRRLQAEHDRQAKELFLLRKTLEEMELRIETQKQTLNARDESI 305
Cdd:pfam10174 81 DELRAQRDLNQLLQQDfttSPVDGEDKFsTPELTEENFRRLQSEHERQAKELFLLRKTLEEMELRIETQKQTLGARDESI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 306 KKLLEMLQSKGLPSKSLEDDNERTRRMAEAESQVSHLEVILDQKEKENIHLREELHRRSQLQPEPAKTKALQTVIEMKDT 385
Cdd:pfam10174 161 KKLLEMLQSKGLPKKSGEEDWERTRRIAEAEMQLGHLEVLLDQKEKENIHLREELHRRNQLQPDPAKTKALQTVIEMKDT 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 386 KIASLERNIRDLEDEIQMLKANGVLNTEDREEEIKQIEVYKSHSKFMKTKIDQLKQELSKKESELLALQTKLETLSNQNS 465
Cdd:pfam10174 241 KISSLERNIRDLEDEVQMLKTNGLLHTEDREEEIKQMEVYKSHSKFMKNKIDQLKQELSKKESELLALQTKLETLTNQNS 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 466 DCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQ 545
Cdd:pfam10174 321 DCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKSTLAGEIRDLKDMLDVKERKINVLQ 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 546 KKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRERLEEIESFRKENKDL 625
Cdd:pfam10174 401 KKIENLQEQLRDKDKQLAGLKERVKSLQTDSSNTDTALTTLEEALSEKERIIERLKEQREREDRERLEELESLKKENKDL 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 626 KEKVNALQAELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEECSKLEAQLKKqaeqlfnqmynpAHNVED 705
Cdd:pfam10174 481 KEKVSALQPELTEKESSLIDLKEHASSLASSGLKKDSKLKSLEIAVEQKKEECSKLENQLKK------------AHNAEE 548
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 706 DSRMNPEFADRIKQLDKEASYYRDECGKAQAEVDRLLEILKEVENEKNDKDKKIAELESLTLRHMKDQNKKVANLKHNQQ 785
Cdd:pfam10174 549 AVRTNPEINDRIRLLEQEVARYKEESGKAQAEVERLLGILREVENEKNDKDKKIAELESLTLRQMKEQNKKVANIKHGQQ 628
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 786 LEKKKNAQLLEEVRRREDSMADNSQHLQIEELMNALEKTRQELDATKARLASTQQSLAEKEAHLANLRIERRKQLEEILE 865
Cdd:pfam10174 629 EMKKKGAQLLEEARRREDNLADNSQQLQLEELMGALEKTRQELDATKARLSSTQQSLAEKDGHLTNLRAERRKQLEEILE 708
|
730 740 750 760 770
....*....|....*....|....*....|....*....|....*....|....*...
gi 1570463013 866 MKQEALLAAISEKDANIALLELSASKKKKTQEEVMALKREKDRLVHQLKQQTQNRMKL 923
Cdd:pfam10174 709 MKQEALLAAISEKDANIALLELSSSKKKKTQEEVMALKREKDRLVHQLKQQTQNRMKL 766
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
363-923 |
2.42e-21 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 100.48 E-value: 2.42e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 363 RSQLQPEPAKTKALQTVIEMKDTKIASLERNIRDLEDEIQMLKANGVLNTEDREEEIKQIEVYKSHSKFMKTKIDQLKQE 442
Cdd:TIGR04523 46 KNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEIKNDKEQKNKLEVE 125
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 443 LSKKE--------------SELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALR---LRLEEKESF 505
Cdd:TIGR04523 126 LNKLEkqkkenkknidkflTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKnklLKLELLLSN 205
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 506 LNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALAT 585
Cdd:TIGR04523 206 LKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKE 285
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 586 LEEALSEKERIIERLKEQRERDdrerleEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKRDSKLK 665
Cdd:TIGR04523 286 LEKQLNQLKSEISDLNNQKEQD------WNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENS 359
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 666 SLEIAIEQKKEECSKLE---AQLKKQAEQLFNQMYNPAHNVEDDSRMNPEFADRIKQLDKEASYYRDECGKAQAEVDRLL 742
Cdd:TIGR04523 360 EKQRELEEKQNEIEKLKkenQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNN 439
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 743 EILKEVENEKNDKDKKIAELESLTlrhmKDQNKKVANLKhnqqLEKKKNAQLLEEVRRREDSmaDNSQHLQIEELMNALE 822
Cdd:TIGR04523 440 SEIKDLTNQDSVKELIIKNLDNTR----ESLETQLKVLS----RSINKIKQNLEQKQKELKS--KEKELKKLNEEKKELE 509
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 823 KTRQELDATKARLASTQQSL----AEKEAHLANLRierRKQLEEILEMKQEALLAAISEKDANIALLELSASKKKKTQEE 898
Cdd:TIGR04523 510 EKVKDLTKKISSLKEKIEKLesekKEKESKISDLE---DELNKDDFELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEE 586
|
570 580
....*....|....*....|....*
gi 1570463013 899 VMALKREKDRLVHQLKQQTQNRMKL 923
Cdd:TIGR04523 587 KQELIDQKEKEKKDLIKEIEEKEKK 611
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
395-931 |
3.21e-21 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 100.40 E-value: 3.21e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 395 RDLEDEIQMLKANGVLNTEDREEEikQIEVYKSHSKFMKTKIDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVL 474
Cdd:COG1196 216 RELKEELKELEAELLLLKLRELEA--ELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYEL 293
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 475 KESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQ 554
Cdd:COG1196 294 LAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAE 373
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 555 LRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRERLEEIESFRKENKDLKEKVNALQA 634
Cdd:COG1196 374 LAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAE 453
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 635 ELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKkeecsKLEAQLKKQAEQlFNQMYNPAHNVEDDSRMNPEFA 714
Cdd:COG1196 454 LEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARL-----LLLLEAEADYEG-FLEGVKAALLLAGLRGLAGAVA 527
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 715 DRIKQLDKEASYYRDECGKA-QAEVDRLLEILKEVENEknDKDKKIAELESLTLRHMKDQNKKVANLKHNQQLEKK---- 789
Cdd:COG1196 528 VLIGVEAAYEAALEAALAAAlQNIVVEDDEVAAAAIEY--LKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVdlva 605
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 790 -KNAQLLEEVRRREDSMADNSQHLQIEELMNALEKTRQELDATKARLASTQQSLAEKEAHLANLRIERRKQLEEILEMKQ 868
Cdd:COG1196 606 sDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELA 685
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1570463013 869 EALLAAISEKDANIALLELSASKKKKTQEEVMALKREKDRLVHQLKQQTQNRMKLMADNYDED 931
Cdd:COG1196 686 ERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELL 748
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
139-916 |
3.18e-19 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 94.03 E-value: 3.18e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 139 LRQvrdsTMLDLQAQLKELQRENDLL----RKELDIKDSKLGSSMNSIKtfwspELKKERVLRKEEAARMSVLKEQMRvs 214
Cdd:pfam15921 108 LRQ----SVIDLQTKLQEMQMERDAMadirRRESQSQEDLRNQLQNTVH-----ELEAAKCLKEDMLEDSNTQIEQLR-- 176
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 215 heenqHLQLTIQALQDELRTqrdLNHLLQQESGNRGAEHFTieLTEENFRRLQAEHDRQAKELFLLRKTLEEMELRIETQ 294
Cdd:pfam15921 177 -----KMMLSHEGVLQEIRS---ILVDFEEASGKKIYEHDS--MSTMHFRSLGSAISKILRELDTEISYLKGRIFPVEDQ 246
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 295 KQTLNArdESIKKLLEMLQSKGLPSKSLEDDNE-----RTRRMAEAESQV----SHLEVILDQKEKENI----HLREELH 361
Cdd:pfam15921 247 LEALKS--ESQNKIELLLQQHQDRIEQLISEHEveitgLTEKASSARSQAnsiqSQLEIIQEQARNQNSmymrQLSDLES 324
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 362 RRSQLQPEPAKTKAL----------QTVIEMKDTKIASLERN-----IRDLEDEIQMLKAngvlnteDREEEIKQIEVYK 426
Cdd:pfam15921 325 TVSQLRSELREAKRMyedkieelekQLVLANSELTEARTERDqfsqeSGNLDDQLQKLLA-------DLHKREKELSLEK 397
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 427 SHSKFM-------KTKIDQLKQELSKKESELLALQTKLETLsnqNSDCKQHIEVLKESLTAKEQRAailqTEVDALRLRL 499
Cdd:pfam15921 398 EQNKRLwdrdtgnSITIDHLRRELDDRNMEVQRLEALLKAM---KSECQGQMERQMAAIQGKNESL----EKVSSLTAQL 470
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 500 EEKESFLNkktKQLQDLTEEKGTLAGEIRDMKDM---LEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQtds 576
Cdd:pfam15921 471 ESTKEMLR---KVVEELTAKKMTLESSERTVSDLtasLQEKERAIEATNAEITKLRSRVDLKLQELQHLKNEGDHLR--- 544
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 577 sNTDTALATLEEALSEKERIIERLKEQrerddrerleeIESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASA 656
Cdd:pfam15921 545 -NVQTECEALKLQMAEKDKVIEILRQQ-----------IENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEFKIL 612
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 657 GLKRDSKLKSLEIAIEQKKEECSKL----------EAQLKKQAEQLFNQMYNPAHNV----EDDSRMNPEFADRIKQLDK 722
Cdd:pfam15921 613 KDKKDAKIRELEARVSDLELEKVKLvnagserlraVKDIKQERDQLLNEVKTSRNELnslsEDYEVLKRNFRNKSEEMET 692
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 723 EASYYRDECGKAQAEVDRLLEILKEVE--------------NEKNDKDKKIAELESlTLRHMKDQNKKVANLKHNQQLEK 788
Cdd:pfam15921 693 TTNKLKMQLKSAQSELEQTRNTLKSMEgsdghamkvamgmqKQITAKRGQIDALQS-KIQFLEEAMTNANKEKHFLKEEK 771
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 789 KKNAQLLEEVRRREDSMADNSQHLQIEE--LMNALEKTRQELDATKARLASTQQSLAEKEAHLANLRIERRKQLEEIL-- 864
Cdd:pfam15921 772 NKLSQELSTVATEKNKMAGELEVLRSQErrLKEKVANMEVALDKASLQFAECQDIIQRQEQESVRLKLQHTLDVKELQgp 851
|
810 820 830 840 850
....*....|....*....|....*....|....*....|....*....|....*....
gi 1570463013 865 ------EMKQEALL-AAISEKDANIALLELSASKKKKTQEEVMALKREKDRLVHQLKQQ 916
Cdd:pfam15921 852 gytsnsSMKPRLLQpASFTRTHSNVPSSQSTASFLSHHSRKTNALKEDPTRDLKQLLQE 910
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
191-926 |
3.72e-19 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 93.98 E-value: 3.72e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 191 KKERVLRKEEAARMSV---------LKEQM-RVSHEENQHLQLtiQALQDELRTQRDLNHLLQQESgnrgaehftielTE 260
Cdd:TIGR02169 171 KKEKALEELEEVEENIerldliideKRQQLeRLRREREKAERY--QALLKEKREYEGYELLKEKEA------------LE 236
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 261 ENFRRLQAEHDRQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEmlqskglpskslEDDNERTRRMAEAESQVS 340
Cdd:TIGR02169 237 RQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGE------------EEQLRVKEKIGELEAEIA 304
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 341 HLEVILDQKEKEnihLREELHRRSQLQPEPAKTKAlqtVIEMKDTKIASLERNIRDLEDEIQMLKANGVLNTEDREEEIK 420
Cdd:TIGR02169 305 SLERSIAEKERE---LEDAEERLAKLEAEIDKLLA---EIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDK 378
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 421 QIEVYKSHSKFMKTKIDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAkeqraaiLQTEVDALRLRLE 500
Cdd:TIGR02169 379 EFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINE-------LEEEKEDKALEIK 451
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 501 EKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSL-----QTD 575
Cdd:TIGR02169 452 KQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVhgtvaQLG 531
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 576 SSNTDTALAtLEEALSEK------------ERIIERLKEQR-ERDDRERLEEIESFRKENKDLKEK-------------- 628
Cdd:TIGR02169 532 SVGERYATA-IEVAAGNRlnnvvveddavaKEAIELLKRRKaGRATFLPLNKMRDERRDLSILSEDgvigfavdlvefdp 610
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 629 ---------------VNALQA---------------ELTEKESSLIDLKEHASSLASAGLKRDSKLKSLeiaiEQKKEEC 678
Cdd:TIGR02169 611 kyepafkyvfgdtlvVEDIEAarrlmgkyrmvtlegELFEKSGAMTGGSRAPRGGILFSRSEPAELQRL----RERLEGL 686
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 679 SKLEAQLKKQAEQLFNQMYNPAHNVEDDSRMNPEFADRIKQLDKEASYYRDECGKAQAEVDRLLEILKEVENEKNDKDKK 758
Cdd:TIGR02169 687 KRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEAR 766
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 759 IAELEsLTLRHMKDQ-NKKVANLKHNQQLEKKKNAQLLEEVRRRedsmadnsqhlqIEELMNALEKTRQELDATKARLAS 837
Cdd:TIGR02169 767 IEELE-EDLHKLEEAlNDLEARLSHSRIPEIQAELSKLEEEVSR------------IEARLREIEQKLNRLTLEKEYLEK 833
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 838 TQQSLAEKEAHLANLRIERRKQLEEiLEMKQEALLAAISEKDAniALLELSASKKKktqeevmaLKREKDRLVHQLKQQT 917
Cdd:TIGR02169 834 EIQELQEQRIDLKEQIKSIEKEIEN-LNGKKEELEEELEELEA--ALRDLESRLGD--------LKKERDELEAQLRELE 902
|
....*....
gi 1570463013 918 QNRMKLMAD 926
Cdd:TIGR02169 903 RKIEELEAQ 911
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
433-692 |
1.08e-18 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 92.44 E-value: 1.08e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 433 KTKIDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQ 512
Cdd:TIGR02169 673 PAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQE 752
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 513 LQDLTEEKGTLAGEIRDMKDMLEVKERKINVL-----QKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLE 587
Cdd:TIGR02169 753 IENVKSELKELEARIEELEEDLHKLEEALNDLearlsHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLE 832
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 588 EALSEKERIIERLKEQRErddrERLEEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKRDSKLKSL 667
Cdd:TIGR02169 833 KEIQELQEQRIDLKEQIK----SIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEEL 908
|
250 260
....*....|....*....|....*
gi 1570463013 668 EIAIEQKKEECSKLEAQLKKQAEQL 692
Cdd:TIGR02169 909 EAQIEKKRKRLSELKAKLEALEEEL 933
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
348-909 |
1.28e-18 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 91.92 E-value: 1.28e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 348 QKEKENIHLREELHRRSQLQpepAKTKALQTVIEMKDTKIASLERNIRDLEDEIQMLKAngVLNTEDREEEIKQIEVYKS 427
Cdd:COG1196 219 KEELKELEAELLLLKLRELE---AELEELEAELEELEAELEELEAELAELEAELEELRL--ELEELELELEEAQAEEYEL 293
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 428 hskfmKTKIDQLKQELSKKESELLALQTKLETLSNQnsdckqhIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLN 507
Cdd:COG1196 294 -----LAELARLEQDIARLEERRRELEERLEELEEE-------LAELEEELEELEEELEELEEELEEAEEELEEAEAELA 361
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 508 KKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLE 587
Cdd:COG1196 362 EAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEE 441
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 588 EALSEKERIIERLKEQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAG---LKRDSKL 664
Cdd:COG1196 442 EALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKaalLLAGLRG 521
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 665 KSLEIAIEQKKEECS-----------------KLEAQLKKQAEQL------------FNQMYNPAHNVEDDSRMNPEFAD 715
Cdd:COG1196 522 LAGAVAVLIGVEAAYeaaleaalaaalqnivvEDDEVAAAAIEYLkaakagratflpLDKIRARAALAAALARGAIGAAV 601
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 716 RIKQLDKEasyYRDECGKAQAEVDRLLEILKEVENEKNDKDKKIAELESLTLRHMKDQNKKVAnlkhnQQLEKKKNAQLL 795
Cdd:COG1196 602 DLVASDLR---EADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGS-----LTGGSRRELLAA 673
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 796 EEVRRREDSMADNSQHLQIEELMNALEKTRQELDATKARLASTQQSLAEKEAHLANLRIERRKQLEEILEMKQEALLAAI 875
Cdd:COG1196 674 LLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEAL 753
|
570 580 590
....*....|....*....|....*....|....
gi 1570463013 876 SEKDANIALLELsaskkkktQEEVMALKREKDRL 909
Cdd:COG1196 754 EELPEPPDLEEL--------ERELERLEREIEAL 779
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
362-909 |
7.14e-18 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 89.35 E-value: 7.14e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 362 RRSQLQPEPAKTKALQTVIEMKDTKIASLERNIRDLEDEIqmlkangvlntEDREEEIKQIEVYKSHSKFMKTKIDQLKQ 441
Cdd:PRK03918 177 RIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSEL-----------PELREELEKLEKEVKELEELKEEIEELEK 245
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 442 ELSKKESELLALQTKLETLSNQNSDCKQHIEVLKEsltaKEQRAailqTEVDALRLRLEEKESFLNKKTKQLQDLTEEKG 521
Cdd:PRK03918 246 ELESLEGSKRKLEEKIRELEERIEELKKEIEELEE----KVKEL----KELKEKAEEYIKLSEFYEEYLDELREIEKRLS 317
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 522 TLAGEIRDMK---DMLEVKERKINVLQKKIENLQEQLrDKDKQLTNLKDRVKSLQTDSSNTDTALATLE-EALSEKERII 597
Cdd:PRK03918 318 RLEEEINGIEeriKELEEKEERLEELKKKLKELEKRL-EELEERHELYEEAKAKKEELERLKKRLTGLTpEKLEKELEEL 396
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 598 ERLKEQRERDDRERLEEIESFRKENKDLKEKVNALQ----------AELTEKESSLIdLKEHASSLAsaglKRDSKLKSL 667
Cdd:PRK03918 397 EKAKEEIEEEISKITARIGELKKEIKELKKAIEELKkakgkcpvcgRELTEEHRKEL-LEEYTAELK----RIEKELKEI 471
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 668 EIAIEQKKEECSKLEAQLKKQAEQLFN-QMYNPAHNVEddSRMNPEFADRIKQLDKEASYYRDECGKAQAEVDRL---LE 743
Cdd:PRK03918 472 EEKERKLRKELRELEKVLKKESELIKLkELAEQLKELE--EKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLkkeLE 549
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 744 ILKEVENEKNDKDKKIAELEsltlRHMKDQNKKVANLKHNQQLEKKKNAQLLEEVRRREDSMADNSQHLQIEElmNALEK 823
Cdd:PRK03918 550 KLEELKKKLAELEKKLDELE----EELAELLKELEELGFESVEELEERLKELEPFYNEYLELKDAEKELEREE--KELKK 623
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 824 TRQELDATKARLASTQQSLAEKEAHLANLRI----ERRKQLEEILEMKQEALLAAISEKDANIALLELSASKKKKTQEEV 899
Cdd:PRK03918 624 LEEELDKAFEELAETEKRLEELRKELEELEKkyseEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEEL 703
|
570
....*....|
gi 1570463013 900 MALKREKDRL 909
Cdd:PRK03918 704 EEREKAKKEL 713
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
250-924 |
3.18e-17 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 87.48 E-value: 3.18e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 250 GAEHFTIELTEENF------RRLQAEHDRQAKELFLLRKT-------LEEMEL---------RIETQKQTlNARDESIKK 307
Cdd:pfam15921 72 GKEHIERVLEEYSHqvkdlqRRLNESNELHEKQKFYLRQSvidlqtkLQEMQMerdamadirRRESQSQE-DLRNQLQNT 150
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 308 LLEMLQSKGLPSKSLEDDN---ERTRRMAEAESQVSH--LEVILDQKEKENIHLREelHRRSQLQPEPAKTKALQTVIEM 382
Cdd:pfam15921 151 VHELEAAKCLKEDMLEDSNtqiEQLRKMMLSHEGVLQeiRSILVDFEEASGKKIYE--HDSMSTMHFRSLGSAISKILRE 228
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 383 KDTKIASLERNIRDLEDEIQMLKAngvlntedreEEIKQIEVykshskFMKTKIDQLKQELSKKESELLALQTKLETLSN 462
Cdd:pfam15921 229 LDTEISYLKGRIFPVEDQLEALKS----------ESQNKIEL------LLQQHQDRIEQLISEHEVEITGLTEKASSARS 292
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 463 QNSDCKQHIEVLKESltAKEQRAAILqtevdalrlrleekesflnkktKQLQDLTEEKGTLAGEIRDMKDMLEvkerkin 542
Cdd:pfam15921 293 QANSIQSQLEIIQEQ--ARNQNSMYM----------------------RQLSDLESTVSQLRSELREAKRMYE------- 341
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 543 vlqKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRER---DDRERLEEIESFR 619
Cdd:pfam15921 342 ---DKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELSLEKEQNKRlwdRDTGNSITIDHLR 418
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 620 KENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEECSKLEAQLKKQAEQLfnqmynp 699
Cdd:pfam15921 419 RELDDRNMEVQRLEALLKAMKSECQGQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTL------- 491
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 700 ahnvEDDSRMNPEFADRIKQLDKEASYYRDECGKAQAEVDRLLEILKEVENEKNDKDKKIAELESLTLRhMKDQNKKVAN 779
Cdd:pfam15921 492 ----ESSERTVSDLTASLQEKERAIEATNAEITKLRSRVDLKLQELQHLKNEGDHLRNVQTECEALKLQ-MAEKDKVIEI 566
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 780 LKhnQQLEKKknAQLLEEVRRREDSMADNSQHLQIEelmnaLEKTRQELDATKARLASTQQSLAEKEAHLANLRIERRK- 858
Cdd:pfam15921 567 LR--QQIENM--TQLVGQHGRTAGAMQVEKAQLEKE-----INDRRLELQEFKILKDKKDAKIRELEARVSDLELEKVKl 637
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 859 ------QLEEILEMKQE--ALLAAI--SEKDANiALLELSASKKKKTQEEVMALKREKDRLVHQLK------QQTQNRMK 922
Cdd:pfam15921 638 vnagseRLRAVKDIKQErdQLLNEVktSRNELN-SLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKsaqselEQTRNTLK 716
|
..
gi 1570463013 923 LM 924
Cdd:pfam15921 717 SM 718
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
386-865 |
5.30e-17 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 86.63 E-value: 5.30e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 386 KIASLERNIRDLEDEIQMLKANGVLNTEDREEEIKQIEVYKSHskfmKTKIDQLKQELSKKESELLALQTKLETLSNQNS 465
Cdd:PRK02224 207 RLNGLESELAELDEEIERYEEQREQARETRDEADEVLEEHEER----REELETLEAEIEDLRETIAETEREREELAEEVR 282
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 466 DCKQHIEVLKESLT--------------AKEQRAAILQTEVDALRLRLEEKESFLNKKTKQL--------------QDLT 517
Cdd:PRK02224 283 DLRERLEELEEERDdllaeaglddadaeAVEARREELEDRDEELRDRLEECRVAAQAHNEEAeslredaddleeraEELR 362
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 518 EEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERII 597
Cdd:PRK02224 363 EEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTARERV 442
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 598 ERLKEQRE--------------------RDDRERLEEIESfrkENKDLKEKVNALQA------ELTEKESSLIDLKEHAS 651
Cdd:PRK02224 443 EEAEALLEagkcpecgqpvegsphvetiEEDRERVEELEA---ELEDLEEEVEEVEErleraeDLVEAEDRIERLEERRE 519
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 652 SLASAGLKRDSKLKSLEIAIEQKKEECSKLEAQLKKQAEQlfnqmynpAHNVEDDSRmnpEFADRIKQLDKEasyyRDEC 731
Cdd:PRK02224 520 DLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREA--------AAEAEEEAE---EAREEVAELNSK----LAEL 584
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 732 GKAQAEVDRLLEILKEVEN------EKNDKDKKIAELESLTLRHMKDQNKKVAnlkhnqQLEKKKNAQLLEEVRRREDSM 805
Cdd:PRK02224 585 KERIESLERIRTLLAAIADaedeieRLREKREALAELNDERRERLAEKRERKR------ELEAEFDEARIEEAREDKERA 658
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 806 ADnsqhlQIEELMNALEKTRQELDATKARLASTQQSLAEkeahLANLRiERRKQLEEILE 865
Cdd:PRK02224 659 EE-----YLEQVEEKLDELREERDDLQAEIGAVENELEE----LEELR-ERREALENRVE 708
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
331-865 |
7.39e-17 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 86.25 E-value: 7.39e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 331 RMAEAESQVSHLEVILDQKEKENIHLREELhrrsqlqpepaktKALQTVI---EMKDTKIASLERNIRDLEDEIQmlkan 407
Cdd:PRK02224 207 RLNGLESELAELDEEIERYEEQREQARETR-------------DEADEVLeehEERREELETLEAEIEDLRETIA----- 268
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 408 gvlNTEDREEEIK-QIEVYKSHSKFMKTKIDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAA 486
Cdd:PRK02224 269 ---ETEREREELAeEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAE 345
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 487 ILQTEVDALRLRLEEKEsflnkktkqlqdltEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLK 566
Cdd:PRK02224 346 SLREDADDLEERAEELR--------------EEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAE 411
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 567 DRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRE--------------------RDDRERLEEIESfrkENKDLK 626
Cdd:PRK02224 412 DFLEELREERDELREREAELEATLRTARERVEEAEALLEagkcpecgqpvegsphvetiEEDRERVEELEA---ELEDLE 488
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 627 EKVNALQA------ELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEECSKLEAQLKKQAEQlfnqmynpA 700
Cdd:PRK02224 489 EEVEEVEErleraeDLVEAEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREA--------A 560
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 701 HNVEDDSRmnpEFADRIKQLDKEasyyRDECGKAQAEVDRLLEILKEVEN------EKNDKDKKIAELESLTLRHMKDQN 774
Cdd:PRK02224 561 AEAEEEAE---EAREEVAELNSK----LAELKERIESLERIRTLLAAIADaedeieRLREKREALAELNDERRERLAEKR 633
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 775 KKVANL--KHNQ------QLEKKKNAQLLEEVRRREDSMADNSQHLQ---------IEELmNALEKTRQELDATKARLAS 837
Cdd:PRK02224 634 ERKRELeaEFDEarieeaREDKERAEEYLEQVEEKLDELREERDDLQaeigaveneLEEL-EELRERREALENRVEALEA 712
|
570 580
....*....|....*....|....*...
gi 1570463013 838 TQQSLAEKEAHLANLRIERRKQLEEILE 865
Cdd:PRK02224 713 LYDEAEELESMYGDLRAELRQRNVETLE 740
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
329-697 |
2.26e-16 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 84.72 E-value: 2.26e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 329 TRRMAEAESQVSHLEVILDQKEKENIHLREELH-RRSQLQPEPAKTKALQTVIEMKDTKIASLERNIRDLEDEIQMLKAN 407
Cdd:TIGR02168 683 EEKIEELEEKIAELEKALAELRKELEELEEELEqLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAE 762
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 408 GVLNTEDREEEIKQIEVYKSHSKFMKTKIDQLKQELSKKESELLALQTKLETLsnqnsdckqhievlKESLTAKEQRAAI 487
Cdd:TIGR02168 763 IEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLL--------------NEEAANLRERLES 828
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 488 LQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKD 567
Cdd:TIGR02168 829 LERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELES 908
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 568 RVKSLQTDSSNTDTALATLEEALSEKE----RIIERLKEQRERD-------DRERLEEIESFRKENKDLKEKVNAL---- 632
Cdd:TIGR02168 909 KRSELRRELEELREKLAQLELRLEGLEvridNLQERLSEEYSLTleeaealENKIEDDEEEARRRLKRLENKIKELgpvn 988
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1570463013 633 ---QAELTEKESSLIDLKEHASSLASAglkrdskLKSLEIAIEQKKEECSKLEAQLKKQAEQLFNQMY 697
Cdd:TIGR02168 989 laaIEEYEELKERYDFLTAQKEDLTEA-------KETLEEAIEEIDREARERFKDTFDQVNENFQRVF 1049
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
150-835 |
6.80e-16 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 83.18 E-value: 6.80e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 150 LQAQLKELQRENDLLRKELDIKDSKLGSSMNSIktfwsPELKKERVLRKEE----AARMSVLKEQMRVSHEENQHLQLTI 225
Cdd:TIGR02168 244 LQEELKEAEEELEELTAELQELEEKLEELRLEV-----SELEEEIEELQKElyalANEISRLEQQKQILRERLANLERQL 318
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 226 QALQDELRTQRDLNHLLQQESGNRGAEhftIELTEENFRRLQAEHDRQAKELFLLRKTLEEMELRIET----------QK 295
Cdd:TIGR02168 319 EELEAQLEELESKLDELAEELAELEEK---LEELKEELESLEAELEELEAELEELESRLEELEEQLETlrskvaqlelQI 395
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 296 QTLNARDESIKKLLEMLQS---KGLPSKSLEDDNERTRRMAEAESQVSHLEVILDQKEKENIHLREELHR-RSQLQPEPA 371
Cdd:TIGR02168 396 ASLNNEIERLEARLERLEDrreRLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEElREELEEAEQ 475
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 372 KTKALQTVIEMKDTKIASLERNIRDLEDEIQMLKA--------NGVLN----------------------------TEDR 415
Cdd:TIGR02168 476 ALDAAERELAQLQARLDSLERLQENLEGFSEGVKAllknqsglSGILGvlselisvdegyeaaieaalggrlqavvVENL 555
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 416 EEEIKQIEVYKSHSK----------FMKTKIDQLKQELSKKESELLALQTKLETLSNQNS--------------DCKQHI 471
Cdd:TIGR02168 556 NAAKKAIAFLKQNELgrvtflpldsIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRkalsyllggvlvvdDLDNAL 635
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 472 EVLKE-------------------SLT--AKEQRAAIL--QTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIR 528
Cdd:TIGR02168 636 ELAKKlrpgyrivtldgdlvrpggVITggSAKTNSSILerRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELE 715
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 529 DMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDD 608
Cdd:TIGR02168 716 QLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLK 795
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 609 RERL---EEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEECSKLEAQL 685
Cdd:TIGR02168 796 EELKalrEALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESEL 875
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 686 KKqAEQLFNQMYNPAHNVEDDSRmnpEFADRIKQLDKEASYYRDECGKAQAEVDRLLEILKEVENEKNDKDKKIAELESL 765
Cdd:TIGR02168 876 EA-LLNERASLEEALALLRSELE---ELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSL 951
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 766 TLRHMKDQNKKVANLKHNQQ-----LEKKKNA---------QLLEEVRRREDSMadNSQHLQIEELMNALEKTRQELDA- 830
Cdd:TIGR02168 952 TLEEAEALENKIEDDEEEARrrlkrLENKIKElgpvnlaaiEEYEELKERYDFL--TAQKEDLTEAKETLEEAIEEIDRe 1029
|
....*
gi 1570463013 831 TKARL 835
Cdd:TIGR02168 1030 ARERF 1034
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
140-909 |
1.83e-15 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 82.03 E-value: 1.83e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 140 RQVRDSTMLDLQAQLKELQRENDLLRKELDIKDSKLGSSMNSIK--TFWSPELKKERVLRKEEAARMSV----------- 206
Cdd:TIGR02168 276 VSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEelEAQLEELESKLDELAEELAELEEkleelkeeles 355
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 207 LKEQMRVSHEENQHLQLTIQALQDELRTQR-DLNHLLQQESGNRGaehfTIELTEENFRRLQAEHDRQAKELFLLRKTLE 285
Cdd:TIGR02168 356 LEAELEELEAELEELESRLEELEEQLETLRsKVAQLELQIASLNN----EIERLEARLERLEDRRERLQQEIEELLKKLE 431
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 286 EMELriETQKQTLNARDESIKKLLEMLQS--------KGLPSKSLEDDNERTRRMAEAESQVSHLEVILDQKEKENIHLR 357
Cdd:TIGR02168 432 EAEL--KELQAELEELEEELEELQEELERleealeelREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVK 509
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 358 EELHRRSQLqpePAKTKALQTVIEMKDTKIASLERnirDLEDEIQMLKangvlnTEDREEEIKQIEVYKSHSKFMKTKID 437
Cdd:TIGR02168 510 ALLKNQSGL---SGILGVLSELISVDEGYEAAIEA---ALGGRLQAVV------VENLNAAKKAIAFLKQNELGRVTFLP 577
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 438 QLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKkTKQlQDLT 517
Cdd:TIGR02168 578 LDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKKLRPGYRIV-TLD-GDLV 655
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 518 EEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERII 597
Cdd:TIGR02168 656 RPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDL 735
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 598 ERLKEQRERddreRLEEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEhasslasaglkrdsKLKSLEIAIEQKKEE 677
Cdd:TIGR02168 736 ARLEAEVEQ----LEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEA--------------EIEELEAQIEQLKEE 797
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 678 CSKLEAQLKKQAEQLfnqmynpahnveddSRMNPEFAD---RIKQLDKEASYYRDECGKAQAEVDRLLEILKEVENEKND 754
Cdd:TIGR02168 798 LKALREALDELRAEL--------------TLLNEEAANlreRLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEE 863
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 755 KDKKIAELESltlrhmkdqnkkvanlkhnqQLEKKKNAQLLEEVRRREdsmadnsQHLQIEELMNALEKTRQELDATKAR 834
Cdd:TIGR02168 864 LEELIEELES--------------------ELEALLNERASLEEALAL-------LRSELEELSEELRELESKRSELRRE 916
|
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1570463013 835 LASTQQSLAEKEAHLANLRIERRKQLEEILEmKQEALLAAISEKDANIALLELSAskkkktQEEVMALKREKDRL 909
Cdd:TIGR02168 917 LEELREKLAQLELRLEGLEVRIDNLQERLSE-EYSLTLEEAEALENKIEDDEEEA------RRRLKRLENKIKEL 984
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
387-693 |
4.25e-15 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 80.87 E-value: 4.25e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 387 IASLERNIRDLEdeIQMLKANGVLNTEDREEEIkQIEVYKSHSKFMKTKIDQLKQELSKKESELLALQTKLETLSNQnsd 466
Cdd:TIGR02168 195 LNELERQLKSLE--RQAEKAERYKELKAELREL-ELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEK--- 268
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 467 ckqhIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKER------- 539
Cdd:TIGR02168 269 ----LEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEelaelee 344
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 540 KINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRERLEEIESFR 619
Cdd:TIGR02168 345 KLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIE 424
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1570463013 620 KENKDLKE-KVNALQAELTEKESSLIDLKEHASSLASAglkrdskLKSLEIAIEQKKEECSKLEAQLKKQAEQLF 693
Cdd:TIGR02168 425 ELLKKLEEaELKELQAELEELEEELEELQEELERLEEA-------LEELREELEEAEQALDAAERELAQLQARLD 492
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
191-927 |
6.70e-15 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 80.02 E-value: 6.70e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 191 KKERVLRKEEAARMSVLKEQMRVSHEENQHLQLTIQAlQDELRTQRdlnhlLQQESGNRGAEHFTIELTEENFRRLQAEH 270
Cdd:pfam02463 170 KKKEALKKLIEETENLAELIIDLEELKLQELKLKEQA-KKALEYYQ-----LKEKLELEEEYLLYLDYLKLNEERIDLLQ 243
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 271 DRQAKELFLLRKTLEEMELRIETQKQTLNARDEsIKKLLEMLQSKGLPSKSLEDDNERTRRMAEAESQVSHLEVILDQKE 350
Cdd:pfam02463 244 ELLRDEQEEIESSKQEIEKEEEKLAQVLKENKE-EEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKE 322
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 351 KENIHLREELHRRSQLQPEPAKtKALQTVIEMKDTKIASLERNIRDLEDEIQMLKANGVLNTEDREEEIKQIEVYKSHSK 430
Cdd:pfam02463 323 KKKAEKELKKEKEEIEELEKEL-KELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKS 401
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 431 FMKTKIDQLKQELSKKESELLALQTKLETLsnqnsdckqhIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKT 510
Cdd:pfam02463 402 EEEKEAQLLLELARQLEDLLKEEKKEELEI----------LEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSE 471
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 511 KQLQ--DLTEEKGTLAGEIRDMKDMLEV-KERKINVLQKKIENLQEQLrdKDKQLTNLKDRVKSLQTDSSNTDTALATLE 587
Cdd:pfam02463 472 DLLKetQLVKLQEQLELLLSRQKLEERSqKESKARSGLKVLLALIKDG--VGGRIISAHGRLGDLGVAVENYKVAISTAV 549
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 588 EALSEKERIIERLKEQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKRDSKLKSL 667
Cdd:pfam02463 550 IVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGIL 629
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 668 EIAIEQKKEECSKL----EAQLKKQAEQLFNQMYNPAHNVEDDSRMNPEFADRIKQ---LDKEASYYRDEC-----GKAQ 735
Cdd:pfam02463 630 KDTELTKLKESAKAkesgLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAeseLAKEEILRRQLEikkkeQREK 709
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 736 AEVDRLLEILKEVENEKNDKDKKIAELESLTLRHMKDQNKKVANLKHNQQLEKKKNAQLLEEVRRREDSMAD----NSQH 811
Cdd:pfam02463 710 EELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREktekLKVE 789
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 812 LQIEELMNALEKTRQELDATKARLASTQQSLAEKEAHLANLRIERRKQLEEILEMKQEALLAAISEKDANIALLELSASK 891
Cdd:pfam02463 790 EEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELL 869
|
730 740 750
....*....|....*....|....*....|....*.
gi 1570463013 892 KKKTQEEVMaLKREKDRLVHQLKQQTQNRMKLMADN 927
Cdd:pfam02463 870 QELLLKEEE-LEEQKLKDELESKEEKEKEEKKELEE 904
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
435-786 |
6.89e-15 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 80.10 E-value: 6.89e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 435 KIDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEvLKESLTAKEqrAAILQTEVDALRLRLEEKESFLNKKTKQLQ 514
Cdd:TIGR02168 180 KLERTRENLDRLEDILNELERQLKSLERQAEKAERYKE-LKAELRELE--LALLVLRLEELREELEELQEELKEAEEELE 256
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 515 DLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDssntdtalatleeaLSEKE 594
Cdd:TIGR02168 257 ELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQ--------------LEELE 322
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 595 RIIERLKEQRERDdRERLEEIEsfrKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQK 674
Cdd:TIGR02168 323 AQLEELESKLDEL-AEELAELE---EKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASL 398
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 675 KEECSKLEAQL--------KKQAEQLFNQMYNPAHNVEDDSRMNPEFADRIKQLDKEASYYRDECGKAQAEVDRLLEILK 746
Cdd:TIGR02168 399 NNEIERLEARLerledrreRLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALD 478
|
330 340 350 360
....*....|....*....|....*....|....*....|
gi 1570463013 747 EVENEKNDKDKKIAELESLTLRHMKDQNKKVANLKHNQQL 786
Cdd:TIGR02168 479 AAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGL 518
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
298-916 |
1.39e-14 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 78.95 E-value: 1.39e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 298 LNARDESIKKLLEmlQSKGLpSKSLEDDNERTRRMAEAESQVSHLEVILDQKEKENIHLreelhrrsQLQPEPA-KTKAL 376
Cdd:TIGR02168 150 IEAKPEERRAIFE--EAAGI-SKYKERRKETERKLERTRENLDRLEDILNELERQLKSL--------ERQAEKAeRYKEL 218
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 377 QTviEMKDTKIASLERNIRDLEDEIQMLKANGVLNTEDREEEIKQIEVYKShskfmktKIDQLKQELSKKESELLALQTK 456
Cdd:TIGR02168 219 KA--ELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEE-------KLEELRLEVSELEEEIEELQKE 289
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 457 LETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEV 536
Cdd:TIGR02168 290 LYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEE 369
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 537 KERKINVLQKKIEN-------LQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKEriierLKEQRERDDR 609
Cdd:TIGR02168 370 LESRLEELEEQLETlrskvaqLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAE-----LKELQAELEE 444
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 610 ERlEEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASaglkrdsKLKSLEiAIEQKKEECSKLEAQLKKQA 689
Cdd:TIGR02168 445 LE-EELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQA-------RLDSLE-RLQENLEGFSEGVKALLKNQ 515
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 690 EQL------------FNQMYNPAHNVEDDSRM------NPEFADRIKQLDKEASYYR------DECGKAQAEVDRLlEIL 745
Cdd:TIGR02168 516 SGLsgilgvlselisVDEGYEAAIEAALGGRLqavvveNLNAAKKAIAFLKQNELGRvtflplDSIKGTEIQGNDR-EIL 594
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 746 KEVENEK---NDKDKKIAELESLtLRHMKDQNKKVANLKHNQQLEKKKNAQLL------EEVRR---------------- 800
Cdd:TIGR02168 595 KNIEGFLgvaKDLVKFDPKLRKA-LSYLLGGVLVVDDLDNALELAKKLRPGYRivtldgDLVRPggvitggsaktnssil 673
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 801 -REDSMADNSQhlQIEELMNALEKTRQELDATKARLASTQQSLAEKEA---------HLANLRIERRKQLEEILEMKQEA 870
Cdd:TIGR02168 674 eRRREIEELEE--KIEELEEKIAELEKALAELRKELEELEEELEQLRKeleelsrqiSALRKDLARLEAEVEQLEERIAQ 751
|
650 660 670 680
....*....|....*....|....*....|....*....|....*.
gi 1570463013 871 LLAAISEKDANIALLElsaSKKKKTQEEVMALKREKDRLVHQLKQQ 916
Cdd:TIGR02168 752 LSKELTELEAEIEELE---ERLEEAEEELAEAEAEIEELEAQIEQL 794
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
149-902 |
2.98e-14 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 77.80 E-value: 2.98e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 149 DLQAQLKELQRENDLLRKELDIKDSKLgssmnsiktfwsPELKKE----RVLRKEEAARMSVLKEqmrvshEENQHLQLT 224
Cdd:TIGR02169 234 ALERQKEAIERQLASLEEELEKLTEEI------------SELEKRleeiEQLLEELNKKIKDLGE------EEQLRVKEK 295
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 225 IQALQDELRTQRDLNHLLQQEsgnrgaehftIELTEENFRRLQAEHDRQAKELFLLRKTLEEMELRietqKQTLNARDES 304
Cdd:TIGR02169 296 IGELEAEIASLERSIAEKERE----------LEDAEERLAKLEAEIDKLLAEIEELEREIEEERKR----RDKLTEEYAE 361
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 305 IKKLLEMLQSKglpSKSLEDDNERTRrmaeaESQVSHLEVILDQKEKENIHLREELHRRSQLQPEPAKTKALQTVIEMKD 384
Cdd:TIGR02169 362 LKEELEDLRAE---LEEVDKEFAETR-----DELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIE 433
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 385 TKIASLERNIRDLEDEIQMLKANGVLNTEDREEEIKQIEVykshskfMKTKIDQLKQELSKKESELLALQTKLETLSNQN 464
Cdd:TIGR02169 434 AKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYD-------LKEEYDRVEKELSKLQRELAEAEAQARASEERV 506
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 465 SDCKQHIEVLKESLTA-----------KEQRAAILQ-------------TEVDA------LRLRLEEKESF--LNKKTKQ 512
Cdd:TIGR02169 507 RGGRAVEEVLKASIQGvhgtvaqlgsvGERYATAIEvaagnrlnnvvveDDAVAkeaielLKRRKAGRATFlpLNKMRDE 586
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 513 LQDLteEKGTLAGEIRDMKDMLEVKERKINVL---------------------QKKIENLQEQLRDKDKQLTNLKDRVKS 571
Cdd:TIGR02169 587 RRDL--SILSEDGVIGFAVDLVEFDPKYEPAFkyvfgdtlvvedieaarrlmgKYRMVTLEGELFEKSGAMTGGSRAPRG 664
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 572 LQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRERLEeiesFRKENKDLKEKVNALQAELTEKESSLIDLKEHAS 651
Cdd:TIGR02169 665 GILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDE----LSQELSDASRKIGEIEKEIEQLEQEEEKLKERLE 740
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 652 SLAsaglkrdSKLKSLEIAIEQKKEECSKLEAQLKKQAEQLfNQMYNPAHNVEDDSRMnpefaDRIKQLDKEASYYRDEC 731
Cdd:TIGR02169 741 ELE-------EDLSSLEQEIENVKSELKELEARIEELEEDL-HKLEEALNDLEARLSH-----SRIPEIQAELSKLEEEV 807
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 732 GKAQAEVDRLLEILKEVENEKNDKDKKIAELESLtLRHMKDQNKKVANLKHNQQLEKKKNAQLLEEVRRREdsmadnsqh 811
Cdd:TIGR02169 808 SRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQ-RIDLKEQIKSIEKEIENLNGKKEELEEELEELEAAL--------- 877
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 812 LQIEELMNALEKTRQELDATKARLASTQQSLA----EKEAHLANLRIERRKQLEEILEMkqEALLAAISEKDANIALLEL 887
Cdd:TIGR02169 878 RDLESRLGDLKKERDELEAQLRELERKIEELEaqieKKRKRLSELKAKLEALEEELSEI--EDPKGEDEEIPEEELSLED 955
|
810
....*....|....*
gi 1570463013 888 SASKKKKTQEEVMAL 902
Cdd:TIGR02169 956 VQAELQRVEEEIRAL 970
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
254-687 |
4.99e-14 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 76.98 E-value: 4.99e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 254 FTIELTEENFRRLQAEHDRQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQS--KGLPSKSLEDDNERTRr 331
Cdd:TIGR04523 204 SNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKikKQLSEKQKELEQNNKK- 282
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 332 MAEAESQVSHLEV-ILDQKEKENIHLREELHrrSQLQPEPAKTKALQTVIEMKDTKIASLERNIRDLEDEIQMLKANGVL 410
Cdd:TIGR04523 283 IKELEKQLNQLKSeISDLNNQKEQDWNKELK--SELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSE 360
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 411 NTEDREEEIKQIEV-------YKSHSKFMKTKIDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQ 483
Cdd:TIGR04523 361 KQRELEEKQNEIEKlkkenqsYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNS 440
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 484 RAAILQTEVDALRLRLEEkesfLNKKTKQLQDLTEekgTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLT 563
Cdd:TIGR04523 441 EIKDLTNQDSVKELIIKN----LDNTRESLETQLK---VLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVK 513
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 564 NLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRErlEEIESFRKENKDLKEKVNALQAELTEKESSL 643
Cdd:TIGR04523 514 DLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELKKENLE--KEIDEKNKEIEELKQTQKSLKKKQEEKQELI 591
|
410 420 430 440
....*....|....*....|....*....|....*....|....
gi 1570463013 644 IDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEECSKLEAQLKK 687
Cdd:TIGR04523 592 DQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKN 635
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
222-922 |
6.89e-14 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 77.10 E-value: 6.89e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 222 QLTIQALQDELRTQRDLNHLLQQESGNRGAEHFTIELTEENFRRLQAEHDRQAKELFLLRKTLEEMELRIETQKQTLNAR 301
Cdd:PTZ00121 1031 ELTEYGNNDDVLKEKDIIDEDIDGNHEGKAEAKAHVGQDEGLKPSYKDFDFDAKEDNRADEATEEAFGKAEEAKKTETGK 1110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 302 DESIKKLLEMLQSKGLPSKSLE-DDNERTRRMAEAESQVSHLEVILDQKEKENihLREELHRRSQLQPEPAKTKALQTVI 380
Cdd:PTZ00121 1111 AEEARKAEEAKKKAEDARKAEEaRKAEDARKAEEARKAEDAKRVEIARKAEDA--RKAEEARKAEDAKKAEAARKAEEVR 1188
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 381 EMKDTKIASLERNIRDLEDEIQMLKANGVLNTED--REEEIKQIEVYKSHSKFMKTKIDQLKQELSKKESELLALQTKLE 458
Cdd:PTZ00121 1189 KAEELRKAEDARKAEAARKAEEERKAEEARKAEDakKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARR 1268
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 459 TLSNQNSDCKQHIEVLK--ESLTAKEQRAAILQTEVDALRLRLEEKesflnKKTKQLQDLTEEKGTLAGEIR----DMKD 532
Cdd:PTZ00121 1269 QAAIKAEEARKADELKKaeEKKKADEAKKAEEKKKADEAKKKAEEA-----KKADEAKKKAEEAKKKADAAKkkaeEAKK 1343
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 533 MLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRERL 612
Cdd:PTZ00121 1344 AAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEA 1423
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 613 EEIESFRKENKDLKEKvnalqAELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIaieQKKEECSKLEAQLKKQAEQl 692
Cdd:PTZ00121 1424 KKKAEEKKKADEAKKK-----AEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEA---KKKAEEAKKADEAKKKAEE- 1494
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 693 fnqmynpAHNVEDDSRMNPEFADRIKQLDKEASYYRDECGKAQAEVDRLLEILKEVENEKNDKDKKIAELEsltlrhmKD 772
Cdd:PTZ00121 1495 -------AKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELK-------KA 1560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 773 QNKKVANLKHNQQLEKKKNAQLLEEVRRREDSMADNSQHLQIEELMNALEKTRQELDA-TKARLASTQQSLAEKEAHLAN 851
Cdd:PTZ00121 1561 EEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAkIKAEELKKAEEEKKKVEQLKK 1640
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1570463013 852 LRIERRKQLEEILEMKQE-----ALLAAISEKDANIALLELSASKKKKTQEEVMALKREKDRLVHQLKQQTQNRMK 922
Cdd:PTZ00121 1641 KEAEEKKKAEELKKAEEEnkikaAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKK 1716
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
135-647 |
1.35e-13 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 75.46 E-value: 1.35e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 135 VPSMLRQVRDStMLDLQAQLKElqRENDLLRKELDIKDSKLGSSMNSIKTFwspELKKER-VLRKEEAARMSVLKEQMR- 212
Cdd:PRK02224 178 VERVLSDQRGS-LDQLKAQIEE--KEEKDLHERLNGLESELAELDEEIERY---EEQREQaRETRDEADEVLEEHEERRe 251
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 213 ---VSHEENQHLQLTI-------QALQDELRTQRDLNHLLQQESGNRGAEhftIELTEENFRRLQAEHDRQAKELFLLRK 282
Cdd:PRK02224 252 eleTLEAEIEDLRETIaetererEELAEEVRDLRERLEELEEERDDLLAE---AGLDDADAEAVEARREELEDRDEELRD 328
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 283 TLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLPSKSLEDDNERTRR-MAEAESQVSHLEVILDQKEKENIHLREELH 361
Cdd:PRK02224 329 RLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREaVEDRREEIEELEEEIEELRERFGDAPVDLG 408
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 362 RRSQLQPEPAKTKalqtviEMKDTKIASLERNIRDLEDEI---QMLKANG--------------VLNTEDREEEIKQIEV 424
Cdd:PRK02224 409 NAEDFLEELREER------DELREREAELEATLRTARERVeeaEALLEAGkcpecgqpvegsphVETIEEDRERVEELEA 482
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 425 YKSHskfMKTKIDQLKQELSKKEsELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKES 504
Cdd:PRK02224 483 ELED---LEEEVEEVEERLERAE-DLVEAEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKRE 558
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 505 FLNKKTKQLQDLTEEKGTLAGE-------------IRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKS 571
Cdd:PRK02224 559 AAAEAEEEAEEAREEVAELNSKlaelkerieslerIRTLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKRE 638
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 572 LQT--DSSNTDTALATLEEALSEKERIIERLKEQRERDD---------RERLEEIESFRKENKDLKEKVNALQA---ELT 637
Cdd:PRK02224 639 LEAefDEARIEEAREDKERAEEYLEQVEEKLDELREERDdlqaeigavENELEELEELRERREALENRVEALEAlydEAE 718
|
570
....*....|
gi 1570463013 638 EKESSLIDLK 647
Cdd:PRK02224 719 ELESMYGDLR 728
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
476-692 |
1.97e-13 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 73.64 E-value: 1.97e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 476 ESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQL 555
Cdd:COG4942 20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 556 rdkDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRerddRERLEEIESFRKENKDLKEKVNALQAE 635
Cdd:COG4942 100 ---EAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLA----PARREQAEELRADLAELAALRAELEAE 172
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 1570463013 636 LTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEEcsklEAQLKKQAEQL 692
Cdd:COG4942 173 RAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAE----LAELQQEAEEL 225
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
488-874 |
1.14e-12 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 72.79 E-value: 1.14e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 488 LQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIrdmkdmlEVKERKINVLQKKIENLQEQLRDKDKQLTNLKD 567
Cdd:TIGR02169 686 LKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEI-------EQLEQEEEKLKERLEELEEDLSSLEQEIENVKS 758
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 568 RvkslqtdssntdtaLATLEEALSEKERIIERLKEQRER-DDRERLEEIESFRKENKDLKEKVNALQAELTEKESSLidl 646
Cdd:TIGR02169 759 E--------------LKELEARIEELEEDLHKLEEALNDlEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKL--- 821
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 647 kehasslasagLKRDSKLKSLEIAIEQKKEECSKLEAQLKKQAEQlfnqmynpahnVEDDSRMNPEFADRIKQLDKEASY 726
Cdd:TIGR02169 822 -----------NRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKE-----------IENLNGKKEELEEELEELEAALRD 879
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 727 YRDECGKAQAEVDRLLEILKEVENEKNDKDKKIAELESltlrHMKDQNKKVANLKHN-QQLEKKKNAqlLEEVRRREDSM 805
Cdd:TIGR02169 880 LESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRK----RLSELKAKLEALEEElSEIEDPKGE--DEEIPEEELSL 953
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1570463013 806 ADNSQHLQ-IEELMNALE----KTRQELDATKARLastqQSLAEKEAHLANLRIERRKQLEEILEMKQEALLAA 874
Cdd:TIGR02169 954 EDVQAELQrVEEEIRALEpvnmLAIQEYEEVLKRL----DELKEKRAKLEEERKAILERIEEYEKKKREVFMEA 1023
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
198-791 |
1.55e-12 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 72.06 E-value: 1.55e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 198 KEEAARMSVLKE--QMRVSHEENQHLQLTIQALQDElRTQRDLNHLLQQESGNRGAEHFTIELTEENFRRLQAEHDRQAK 275
Cdd:pfam05483 218 KEDHEKIQHLEEeyKKEINDKEKQVSLLLIQITEKE-NKMKDLTFLLEESRDKANQLEEKTKLQDENLKELIEKKDHLTK 296
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 276 ELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEmlqskglpsksleddnERTRRMAEAESQVSHLEVILDQKEKENIH 355
Cdd:pfam05483 297 ELEDIKMSLQRSMSTQKALEEDLQIATKTICQLTE----------------EKEAQMEELNKAKAAHSFVVTEFEATTCS 360
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 356 LrEELHRRSQLQPEPAKTKALQTVIEmkdtkiasLERNIRDLEDEIQMLKangvlNTEDREEEIKQIEVYKSHSKFMKTK 435
Cdd:pfam05483 361 L-EELLRTEQQRLEKNEDQLKIITME--------LQKKSSELEEMTKFKN-----NKEVELEELKKILAEDEKLLDEKKQ 426
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 436 IDQLKQELSKKESELLALqtkLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQD 515
Cdd:pfam05483 427 FEKIAEELKGKEQELIFL---LQAREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEKEKLKNIELTAHCDKLLLENKE 503
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 516 LTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEqlrdkdkQLTNLKDRVKSLQtdssntdtalatlEEALSEKER 595
Cdd:pfam05483 504 LTQEASDMTLELKKHQEDIINCKKQEERMLKQIENLEE-------KEMNLRDELESVR-------------EEFIQKGDE 563
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 596 IIERLkEQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIeqkk 675
Cdd:pfam05483 564 VKCKL-DKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKALKKKGSAENKQLNAYEIKV---- 638
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 676 eecSKLEAQLkKQAEQLFNQMYNPAHNVEDDSRMNPEfaDRIKQLDKeASYYRDECGKAQAEVD-----RLLEILKEVEN 750
Cdd:pfam05483 639 ---NKLELEL-ASAKQKFEEIIDNYQKEIEDKKISEE--KLLEEVEK-AKAIADEAVKLQKEIDkrcqhKIAEMVALMEK 711
|
570 580 590 600
....*....|....*....|....*....|....*....|..
gi 1570463013 751 EKNDKDKKIAELES-LTLRHMKDQNKKVANLKHNQQLEKKKN 791
Cdd:pfam05483 712 HKHQYDKIIEERDSeLGLYKNKEQEQSSAKAALEIELSNIKA 753
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
260-922 |
1.56e-12 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 72.48 E-value: 1.56e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 260 EENFRRLQAEHDRQAKELFLLRKTleEMELRIETQKQTLNARD-ESIKKLLEMLQSKGLpSKSLEDDNERTRRMAEAESQ 338
Cdd:PTZ00121 1137 EDARKAEEARKAEDAKRVEIARKA--EDARKAEEARKAEDAKKaEAARKAEEVRKAEEL-RKAEDARKAEAARKAEEERK 1213
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 339 VSHLEVILDQKEKENIHLREELHRRSQLQPEPAKTKALQTVIEMKDTKIASLERNIRDLEDEiQMLKANGVLNTED--RE 416
Cdd:PTZ00121 1214 AEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAE-EARKADELKKAEEkkKA 1292
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 417 EEIKQIEVYKSHSKFMKTKIDQLKQELSKKESEllALQTKLETLSNQNSDCKQHIEVLK--ESLTAKEQRAAILQTEVDA 494
Cdd:PTZ00121 1293 DEAKKAEEKKKADEAKKKAEEAKKADEAKKKAE--EAKKKADAAKKKAEEAKKAAEAAKaeAEAAADEAEAAEEKAEAAE 1370
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 495 LRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKinvlQKKIENLQEQLRDKDKqltnlKDRVKSLQT 574
Cdd:PTZ00121 1371 KKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAA----KKKADEAKKKAEEKKK-----ADEAKKKAE 1441
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 575 DSSNTDTALATLEEAlSEKERIIERLKEQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESSlidlKEHASSLA 654
Cdd:PTZ00121 1442 EAKKADEAKKKAEEA-KKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEA----KKKADEAK 1516
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 655 SAGLKRdsKLKSLEIAIEQKKEECSKlEAQLKKQAEQLfnqmyNPAHNVEDDSRMNPEFADRIKQLDKEASYYRDECGKa 734
Cdd:PTZ00121 1517 KAEEAK--KADEAKKAEEAKKADEAK-KAEEKKKADEL-----KKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAK- 1587
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 735 QAEVDRLLEILKEVENEKNDKDKKI-----AELESLTLRHMKDQNKKVANLKHNQQLEKKKnaqlLEEVRRREDSmadns 809
Cdd:PTZ00121 1588 KAEEARIEEVMKLYEEEKKMKAEEAkkaeeAKIKAEELKKAEEEKKKVEQLKKKEAEEKKK----AEELKKAEEE----- 1658
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 810 qhlqiEELMNALEKTRQELDATKARLASTQQSLAEKEAHLANLRIERRKQLEEILEMKQEallaaisekdaniallelsa 889
Cdd:PTZ00121 1659 -----NKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAE-------------------- 1713
|
650 660 670
....*....|....*....|....*....|...
gi 1570463013 890 skKKKTQEEVMALKREKDRLVHQLKQQTQNRMK 922
Cdd:PTZ00121 1714 --EKKKAEELKKAEEENKIKAEEAKKEAEEDKK 1744
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
220-877 |
2.99e-12 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 71.25 E-value: 2.99e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 220 HLQLTIQALQDELRTQRDLNHLLQQESGNRGAEHFTIELTEENFRRLQAEHD---RQAKELFLLRKTLEEMELRIETQKQ 296
Cdd:PRK03918 173 EIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEkleKEVKELEELKEEIEELEKELESLEG 252
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 297 TLNARDESIKKLLEMLQSKGLPSKSLEDDNERTRRMAEAESQVSHLEVILDQKEKENIHLREELHRRSQlqpepaktkal 376
Cdd:PRK03918 253 SKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEE----------- 321
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 377 qtviemkdtKIASLERNIRDLEDeiqmlKANGVLNTEDREEEI-KQIEVYKSHSKfmktkidqLKQELSKKESELLALQT 455
Cdd:PRK03918 322 ---------EINGIEERIKELEE-----KEERLEELKKKLKELeKRLEELEERHE--------LYEEAKAKKEELERLKK 379
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 456 KLETLSnqnsdckqhIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDmlE 535
Cdd:PRK03918 380 RLTGLT---------PEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCGRELTE--E 448
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 536 VKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNtdtalatlEEALSEKERIIERLKEQRERDDRERLEEI 615
Cdd:PRK03918 449 HRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKK--------ESELIKLKELAEQLKELEEKLKKYNLEEL 520
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 616 ESFRKENKDLKEKVNALQAELTEKESSLIDLKEHasslasaglkrDSKLKSLEIAIEQKKEECSKLEAQLKKQAEQLFNq 695
Cdd:PRK03918 521 EKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEEL-----------KKKLAELEKKLDELEEELAELLKELEELGFESVE- 588
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 696 mynpahnveddsrmnpEFADRIKQLDKeasyYRDECGKAQAEVDRLLEILKEVENEKNDKDKKIAELEsLTLRHMKDQNK 775
Cdd:PRK03918 589 ----------------ELEERLKELEP----FYNEYLELKDAEKELEREEKELKKLEEELDKAFEELA-ETEKRLEELRK 647
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 776 KVanlkhnQQLEKKKNAQLLEEVRRR--EDSMADNSQHLQIEELMNALEKTRQELDATKARLASTQQslAEKEAHLANLR 853
Cdd:PRK03918 648 EL------EELEKKYSEEEYEELREEylELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREK--AKKELEKLEKA 719
|
650 660
....*....|....*....|....*
gi 1570463013 854 IERRKQL-EEILEMKQEALLAAISE 877
Cdd:PRK03918 720 LERVEELrEKVKKYKALLKERALSK 744
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
503-695 |
5.96e-12 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 69.09 E-value: 5.96e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 503 ESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLT-----------NLKDRVKS 571
Cdd:COG3883 15 DPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAeaeaeieerreELGERARA 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 572 LQTDSSNTDTALATLE----EALSEKERIIERLKEQrerdDRERLEEIESFRKENKDLKEKVNALQAELTEKESSLIDLK 647
Cdd:COG3883 95 LYRSGGSVSYLDVLLGsesfSDFLDRLSALSKIADA----DADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAK 170
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 1570463013 648 EhasSLASAGLKRDSKLKSLEIAIEQKKEECSKLEAQLKKQAEQLFNQ 695
Cdd:COG3883 171 A---ELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAA 215
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
510-919 |
1.78e-11 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 68.51 E-value: 1.78e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 510 TKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEA 589
Cdd:TIGR04523 39 EKKLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEIKNDKEQ 118
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 590 LSEKERIIERLKEQRERDDRER---LEEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKRDSKL-- 664
Cdd:TIGR04523 119 KNKLEVELNKLEKQKKENKKNIdkfLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLlk 198
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 665 -----------------------------KSLEIAIEQKKEECSKLEAQLKKQAEQLF----------NQMYNPAHNVED 705
Cdd:TIGR04523 199 lelllsnlkkkiqknkslesqiselkkqnNQLKDNIEKKQQEINEKTTEISNTQTQLNqlkdeqnkikKQLSEKQKELEQ 278
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 706 DSRMNPEFADRIKQLDKEASYYRDEcgKAQAEVDRLLEILKEVENEKNDKDKKIAELESlTLRHMKDQ---------NKK 776
Cdd:TIGR04523 279 NNKKIKELEKQLNQLKSEISDLNNQ--KEQDWNKELKSELKNQEKKLEEIQNQISQNNK-IISQLNEQisqlkkeltNSE 355
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 777 VANLKHNQQLEKKKNAqlLEEVRRREDSMADNSQHL--QIEELMNALEKTRQELDATKARLASTQQSLAEKEAHLANLRI 854
Cdd:TIGR04523 356 SENSEKQRELEEKQNE--IEKLKKENQSYKQEIKNLesQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKE 433
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1570463013 855 ERRKQLEEILEMKQEallaaISEKDANIALLElsaSKKKKTQEEVMALKREKDRLVHQLKQQTQN 919
Cdd:TIGR04523 434 TIIKNNSEIKDLTNQ-----DSVKELIIKNLD---NTRESLETQLKVLSRSINKIKQNLEQKQKE 490
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
148-764 |
2.06e-11 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 68.42 E-value: 2.06e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 148 LDLQAQLKELQREndLLRKELDIKDSKLGSSMNSIKtfwspELKKERVLRKEEAARMSVLKEQMRVSHEEnqhLQLTIQA 227
Cdd:COG1196 216 RELKEELKELEAE--LLLLKLRELEAELEELEAELE-----ELEAELEELEAELAELEAELEELRLELEE---LELELEE 285
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 228 LQDEL--------RTQRDLNHL---LQQESGNRGAEHFTIELTEENFRRLQAEHDRQAKELFLLRKTLEEMELRIETQKQ 296
Cdd:COG1196 286 AQAEEyellaelaRLEQDIARLeerRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEE 365
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 297 TLNARDESIKKLLEMLQSKglpsksLEDDNERTRRMAEAESQVSHLEVILDQKEKENIHLREELHRRSQlqpepAKTKAL 376
Cdd:COG1196 366 ALLEAEAELAEAEEELEEL------AEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEE-----ALAELE 434
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 377 QTVIEMKDTKIASLERNIRDLEDEIQMLKANGVLNTEDREEEIKQIEVYKSHSKfmKTKIDQLKQELSKKESELLALQTK 456
Cdd:COG1196 435 EEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAE--AAARLLLLLEAEADYEGFLEGVKA 512
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 457 LETLSNQnsdCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEV 536
Cdd:COG1196 513 ALLLAGL---RGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALA 589
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 537 KERKINVLQKKIENLQEQLRDKDKQLTNLKDrvkSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERddRERLEEIE 616
Cdd:COG1196 590 AALARGAIGAAVDLVASDLREADARYYVLGD---TLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGG--SAGGSLTG 664
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 617 SFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEEcskLEAQLKKQAEQLFNQM 696
Cdd:COG1196 665 GSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEA---LEEQLEAEREELLEEL 741
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1570463013 697 YNPAHNVEDDSRMNPEFADRIKQLDKEASyyrdecgKAQAEVDRL-------LEILKEVENEKNDKDKKIAELES 764
Cdd:COG1196 742 LEEEELLEEEALEELPEPPDLEELERELE-------RLEREIEALgpvnllaIEEYEELEERYDFLSEQREDLEE 809
|
|
| PRK01156 |
PRK01156 |
chromosome segregation protein; Provisional |
284-879 |
3.28e-11 |
|
chromosome segregation protein; Provisional
Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 68.00 E-value: 3.28e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 284 LEEMELRIETQKQTLNARDESIKKLLEMLQSKGLP----SKSLEDDNERTRRMaeaESQVSHLEVILDQKEKENIHLREE 359
Cdd:PRK01156 164 LERNYDKLKDVIDMLRAEISNIDYLEEKLKSSNLEleniKKQIADDEKSHSIT---LKEIERLSIEYNNAMDDYNNLKSA 240
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 360 LHRRSQLQPEPAKtkalqtviemkdtkiasLERNIRDLEDEIQM--LKANGVLNTEDREEEIKQIEVYKSHSKF-----M 432
Cdd:PRK01156 241 LNELSSLEDMKNR-----------------YESEIKTAESDLSMelEKNNYYKELEERHMKIINDPVYKNRNYIndyfkY 303
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 433 KTKIDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKEsltakeqraailQTEVDALRLRLEEKESFLNKKTKQ 512
Cdd:PRK01156 304 KNDIENKKQILSNIDAEINKYHAIIKKLSVLQKDYNDYIKKKSR------------YDDLNNQILELEGYEMDYNSYLKS 371
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 513 LQDLTEEKGTLAGEIRDMKD----MLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEe 588
Cdd:PRK01156 372 IESLKKKIEEYSKNIERMSAfiseILKIQEIDPDAIKKELNEINVKLQDISSKVSSLNQRIRALRENLDELSRNMEMLN- 450
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 589 ALSEKERIIERLKEQRERDDRERLEEiesfrkENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKR----DSKL 664
Cdd:PRK01156 451 GQSVCPVCGTTLGEEKSNHIINHYNE------KKSRLEEKIREIEIEVKDIDEKIVDLKKRKEYLESEEINKsineYNKI 524
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 665 KSLEIAIEQKKEECSKL-EAQLKkqAEQLFNQmYNPAHnVEDDSRMNPEFAD---RIKQLDKEASYYRDECGKAQAE--V 738
Cdd:PRK01156 525 ESARADLEDIKIKINELkDKHDK--YEEIKNR-YKSLK-LEDLDSKRTSWLNalaVISLIDIETNRSRSNEIKKQLNdlE 600
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 739 DRLLEILKEVENEKNDKDKKIAELESlTLRHMKDQNKKVANLKHNQQLEKKKNAQLLEEV---RRREDSMAD-NSQHLQI 814
Cdd:PRK01156 601 SRLQEIEIGFPDDKSYIDKSIREIEN-EANNLNNKYNEIQENKILIEKLRGKIDNYKKQIaeiDSIIPDLKEiTSRINDI 679
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1570463013 815 EELMNALEKTRQELDATKARLASTQQSLAEKEAHLANLRIERRKQLEeilemKQEALLAAISEKD 879
Cdd:PRK01156 680 EDNLKKSRKALDDAKANRARLESTIEILRTRINELSDRINDINETLE-----SMKKIKKAIGDLK 739
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
423-900 |
3.91e-11 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 67.49 E-value: 3.91e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 423 EVYKSHSKFMKTKIDQLK------QELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQtevdaLR 496
Cdd:COG4717 57 ELFKPQGRKPELNLKELKeleeelKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLP-----LY 131
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 497 LRLEEKESFLNKKTKQLQDLTEEkgtlAGEIRDMKDMLEVKERKINVLQKKIENLQEQLR-DKDKQLTNLKDRVKSLQTD 575
Cdd:COG4717 132 QELEALEAELAELPERLEELEER----LEELRELEEELEELEAELAELQEELEELLEQLSlATEEELQDLAEELEELQQR 207
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 576 SSNTDTALATLEEALSEKERIIERLKEQRER-DDRERLEEIESFRKenkdLKEKVNALQAELTEKESSLIDLKEHASSLA 654
Cdd:COG4717 208 LAELEEELEEAQEELEELEEELEQLENELEAaALEERLKEARLLLL----IAAALLALLGLGGSLLSLILTIAGVLFLVL 283
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 655 SAGLKRDSKLKSLEIAIEQKKEECSKLEAQLKKQAEQLFNQMYNPAHNVEDDSRMNPEFADRIKQLDKEASYYRDEcgKA 734
Cdd:COG4717 284 GLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEEL--EE 361
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 735 QAEVDRLLEILKEVENEKNDKDkkIAELEsltlrhmkdqnKKVANLKHNQQLEKKKNaQLLEEVRRREDSMADNSQHLQI 814
Cdd:COG4717 362 ELQLEELEQEIAALLAEAGVED--EEELR-----------AALEQAEEYQELKEELE-ELEEQLEELLGELEELLEALDE 427
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 815 EELMNALEKTRQELDATKARLASTQQSLAEKEAHLANLriERRKQLEEILEmKQEALLAAISEKDANIALLELSASKKKK 894
Cdd:COG4717 428 EELEEELEELEEELEELEEELEELREELAELEAELEQL--EEDGELAELLQ-ELEELKAELRELAEEWAALKLALELLEE 504
|
....*.
gi 1570463013 895 TQEEVM 900
Cdd:COG4717 505 AREEYR 510
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
583-926 |
4.08e-11 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 67.79 E-value: 4.08e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 583 LATLEEALSEKERIIERLKEQRERDDR------ERLEEIESFRKEnKDLKEKVNALQAELTEKESSLI--DLKEHASSLA 654
Cdd:TIGR02169 162 IAGVAEFDRKKEKALEELEEVEENIERldliidEKRQQLERLRRE-REKAERYQALLKEKREYEGYELlkEKEALERQKE 240
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 655 saglKRDSKLKSLEIAIEQKKEECSKLEAQLKkQAEQLFNQMynpahnveddsrmnpefADRIKQL-DKEASYYRDECGK 733
Cdd:TIGR02169 241 ----AIERQLASLEEELEKLTEEISELEKRLE-EIEQLLEEL-----------------NKKIKDLgEEEQLRVKEKIGE 298
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 734 AQAEVDRLLEILKEVENEKNDKDKKIAELESLTLRhmkdQNKKVANLKHNQQLEKKKNAQLLEEVRRREDSMADNSQhlQ 813
Cdd:TIGR02169 299 LEAEIASLERSIAEKERELEDAEERLAKLEAEIDK----LLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRA--E 372
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 814 IEELMNALEKTRQELDATKARLASTQQSLAEKEAHLANLRIERRKQLEEILEMKQEalLAAISEKdaniaLLELSASKKK 893
Cdd:TIGR02169 373 LEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAA--IAGIEAK-----INELEEEKED 445
|
330 340 350
....*....|....*....|....*....|...
gi 1570463013 894 KtQEEVMALKREKDRLVHQLKQQTQNRMKLMAD 926
Cdd:TIGR02169 446 K-ALEIKKQEWKLEQLAADLSKYEQELYDLKEE 477
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
433-641 |
4.40e-11 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 66.33 E-value: 4.40e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 433 KTKIDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQ 512
Cdd:COG4942 26 EAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEE 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 513 LQDL------TEEKGTL-----AGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDT 581
Cdd:COG4942 106 LAELlralyrLGRQPPLalllsPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEE 185
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 582 ALATLEEALSEKERIIERLKEQRERDDrerlEEIESFRKENKDLKEKVNALQAELTEKES 641
Cdd:COG4942 186 ERAALEALKAERQKLLARLEKELAELA----AELAELQQEAEELEALIARLEAEAAAAAE 241
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
153-881 |
7.04e-11 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 66.99 E-value: 7.04e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 153 QLKELQRENDLLRKELDIKDSKLGSSMNSIK--TFWSPELKKERVLRKEEAARMSVLKEQMRVSHEENQHLQltiQALQD 230
Cdd:TIGR00606 353 QLQADRHQEHIRARDSLIQSLATRLELDGFErgPFSERQIKNFHTLVIERQEDEAKTAAQLCADLQSKERLK---QEQAD 429
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 231 ELRTQR-DLNHLLQQESGNRGAEHFTIELTEENFRRLQAEHDRQAKELFLLRKTLEEMELRIETQK-QTLNARDESIKKL 308
Cdd:TIGR00606 430 EIRDEKkGLGRTIELKKEILEKKQEELKFVIKELQQLEGSSDRILELDQELRKAERELSKAEKNSLtETLKKEVKSLQNE 509
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 309 -LEMLQSKGLPSKSLEDDNERTRRMAEAESQVSHLEVILDQKEKENIHLREELhrrSQLQPEPAKTKALQTVIEMKDTKI 387
Cdd:TIGR00606 510 kADLDRKLRKLDQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDEL---TSLLGYFPNKKQLEDWLHSKSKEI 586
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 388 ASLERNIRDLEDEIQMLKANGVLNTEDREEEIKQIEVYKSH------SKFMKTKIDQLKQELSKKESELLALQTK----- 456
Cdd:TIGR00606 587 NQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKlfdvcgSQDEESDLERLKEEIEKSSKQRAMLAGAtavys 666
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 457 --LETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEI-RDMKDM 533
Cdd:TIGR00606 667 qfITQLTDENQSCCPVCQRVFQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIdLKEKEI 746
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 534 LEVKERKINVlQKKIENLQEQLRDKDKQLTNLKDRVKS---LQTDSsntdTALATLEEALSEKERIIERL---------- 600
Cdd:TIGR00606 747 PELRNKLQKV-NRDIQRLKNDIEEQETLLGTIMPEEESakvCLTDV----TIMERFQMELKDVERKIAQQaaklqgsdld 821
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 601 -------KEQRERDDRER--LEEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEHAS---SLASAGLKRDSKLKSLE 668
Cdd:TIGR00606 822 rtvqqvnQEKQEKQHELDtvVSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQrrqQFEEQLVELSTEVQSLI 901
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 669 IAIEQKKEECSKLEAQLKK---QAEQLFNQMYNPAHNVEDDSRMNPEFADRIKQLDKEA-SYYRDECGKAQAEVDRLLEI 744
Cdd:TIGR00606 902 REIKDAKEQDSPLETFLEKdqqEKEELISSKETSNKKAQDKVNDIKEKVKNIHGYMKDIeNKIQDGKDDYLKQKETELNT 981
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 745 LKEVENEKNDKDKKIAELESLTLRHMKDQNKKVANLKHNQQLEKKKNAqlLEEVRRREDSMADNSQHLQIEELMNALEKT 824
Cdd:TIGR00606 982 VNAQLEECEKHQEKINEDMRLMRQDIDTQKIQERWLQDNLTLRKRENE--LKEVEEELKQHLKEMGQMQVLQMKQEHQKL 1059
|
730 740 750 760 770
....*....|....*....|....*....|....*....|....*....|....*....
gi 1570463013 825 RQELDATKAR--LASTQQSLAEKEAHLANLRIeRRKQLEEILEMKQEALLAAISEKDAN 881
Cdd:TIGR00606 1060 EENIDLIKRNhvLALGRQKGYEKEIKHFKKEL-REPQFRDAEEKYREMMIVMRTTELVN 1117
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
282-930 |
7.47e-11 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 66.92 E-value: 7.47e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 282 KTLEEMELRIETQKQTLNARDESIKKLLEMLQ-SKGLPSKSLEDDNERTRRMAEAESQVSHLEVILDQKEKENIHLREEL 360
Cdd:pfam02463 174 ALKKLIEETENLAELIIDLEELKLQELKLKEQaKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEI 253
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 361 HRRSQLQPEPAKTKALQTVIEMKDTKIASLERNIRD-LEDEIQMLKANGVLNTEDREEEIKQIEVYKSHSKFMKTKIDQL 439
Cdd:pfam02463 254 ESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKlLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKE 333
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 440 KQELSKKESELLALQTKLETLSNQNSDCKQhieVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEE 519
Cdd:pfam02463 334 KEEIEELEKELKELEIKREAEEEEEEELEK---LQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLL 410
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 520 KGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLR-DKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIE 598
Cdd:pfam02463 411 LELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTeEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLL 490
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 599 RLKEQRERDDRER--LEEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKKE 676
Cdd:pfam02463 491 SRQKLEERSQKESkaRSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRAL 570
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 677 ECSKLEAQLKKQAEQLFNQMYNPAHNVEDDSRMNPEFADRIKQLDKEASYYRDECGKAQAEVDRLLEILKEVENEKNDKD 756
Cdd:pfam02463 571 TELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRK 650
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 757 KKIAELESLTLRHMKDQNKKVANLKHNQQLEKKKNAQLL--EEVRRREDSMADNSQHLQIEELMNALEKTRQELDATK-- 832
Cdd:pfam02463 651 GVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELakEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQea 730
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 833 -----ARLASTQQSLAEKEAHLANLRIERRKQLEEILEMKQEALLAAISEKDANIALLELSASKKKKTQEEVMALKREKD 907
Cdd:pfam02463 731 qdkinEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEEL 810
|
650 660
....*....|....*....|...
gi 1570463013 908 RLVHQLKQQTQNRMKLMADNYDE 930
Cdd:pfam02463 811 KEEAELLEEEQLLIEQEEKIKEE 833
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
330-913 |
9.05e-11 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 66.48 E-value: 9.05e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 330 RRMAEAESQVSHLEVILDQKEKenihLREELHRRSQLQPEPAKTKALQtviemKDTKIASLERNIRDLEDEIQMLKAngv 409
Cdd:COG4913 242 EALEDAREQIELLEPIRELAER----YAAARERLAELEYLRAALRLWF-----AQRRLELLEAELEELRAELARLEA--- 309
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 410 lntedreeeikqievykshskfmktKIDQLKQELSKKESELLALQTKLETLSNQN-SDCKQHIEVLKESLTAKEQRAAIL 488
Cdd:COG4913 310 -------------------------ELERLEARLDALREELDELEAQIRGNGGDRlEQLEREIERLERELEERERRRARL 364
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 489 QTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKinvlqkkienLQEQLRDKDKQLTNLKDR 568
Cdd:COG4913 365 EALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRD----------LRRELRELEAEIASLERR 434
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 569 VKSLqtdSSNTDTALATLEEALSEKE---RIIERLKEQRERDDR-----ERL------------EEIESFRK--ENKDLK 626
Cdd:COG4913 435 KSNI---PARLLALRDALAEALGLDEaelPFVGELIEVRPEEERwrgaiERVlggfaltllvppEHYAAALRwvNRLHLR 511
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 627 EKVNALQAELTEKESSLIDLkeHASSLASaglkrdsKLKSLEIAIEQKkeecskLEAQLKKQ--------AEQLFN---- 694
Cdd:COG4913 512 GRLVYERVRTGLPDPERPRL--DPDSLAG-------KLDFKPHPFRAW------LEAELGRRfdyvcvdsPEELRRhpra 576
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 695 -----QMYNPAHNVE-DDSRMNPEF-------ADRIKQLDKEAsyyrdecGKAQAEVDRLLEILKEVENEKNDKDKKIAE 761
Cdd:COG4913 577 itragQVKGNGTRHEkDDRRRIRSRyvlgfdnRAKLAALEAEL-------AELEEELAEAEERLEALEAELDALQERREA 649
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 762 LESLTlrhmkdqnkkvanlkhNQQLEKKKNAQLLEEVRRREDSM----ADNSQHLQIEELMNALEKTRQELDATKARLAS 837
Cdd:COG4913 650 LQRLA----------------EYSWDEIDVASAEREIAELEAELerldASSDDLAALEEQLEELEAELEELEEELDELKG 713
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1570463013 838 TQQSLAEKEAHLANLRIERRKQLEEILEMKQEALLAAISEKDANIALLELSASKKKKTQEEVMALKREKDRLVHQL 913
Cdd:COG4913 714 EIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVERELRENLEERIDALRARLNRAEEEL 789
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
506-915 |
2.36e-10 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 65.09 E-value: 2.36e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 506 LNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQL---RDKDKQLTNLKDRVKSLQTDSSNTDTA 582
Cdd:PRK03918 174 IKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELeklEKEVKELEELKEEIEELEKELESLEGS 253
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 583 LATLEEALSEKERIIERLKEQRE--RDDRERLEEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKR 660
Cdd:PRK03918 254 KRKLEEKIRELEERIEELKKEIEelEEKVKELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKEL 333
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 661 DSKLKSLEiAIEQKKEECSKLEAQLKKQAEQLFNQMYNPAHNVEDDSRMNPEFADRIKQLDKEASYYRDEcgkAQAEVDR 740
Cdd:PRK03918 334 EEKEERLE-ELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTPEKLEKELEELEKAKEE---IEEEISK 409
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 741 LLEILKEVENEKNDKDKKIAELES-----------LTLRHMKDQNKKVANLKHNQQLEKKKNAQLLEEVRRREDSMadnS 809
Cdd:PRK03918 410 ITARIGELKKEIKELKKAIEELKKakgkcpvcgreLTEEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELREL---E 486
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 810 QHLQIEELMNALEKTRQELDATKARLASTQQSLAEKEAHlanlriERRKQLEEILEMKQEallaaISEKDANIALLELSA 889
Cdd:PRK03918 487 KVLKKESELIKLKELAEQLKELEEKLKKYNLEELEKKAE------EYEKLKEKLIKLKGE-----IKSLKKELEKLEELK 555
|
410 420
....*....|....*....|....*.
gi 1570463013 890 SKKKKTQEEVMALKREKDRLVHQLKQ 915
Cdd:PRK03918 556 KKLAELEKKLDELEEELAELLKELEE 581
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
189-921 |
5.27e-10 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 64.39 E-value: 5.27e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 189 ELKKERVLRKEEAARMSVLK--EQMRVSHEENQHLQLTIQALQDELRTQRDLNHLLQQESGNRGAEHFTIELTEENFRRL 266
Cdd:PTZ00121 1211 ERKAEEARKAEDAKKAEAVKkaEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKK 1290
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 267 QAEHDRQAKElfllRKTLEEMELRIETQKQT--LNARDESIKKLLEMLQSKGLPSKSLEDDNERTRRMAEAESQVSHLEV 344
Cdd:PTZ00121 1291 KADEAKKAEE----KKKADEAKKKAEEAKKAdeAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKA 1366
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 345 ILDQKEKENIHLR-EELHRRSQ--LQPEPAKTKALQTVIEMKDTKIASLERNIRD-----LEDEIQMLKANGVLNTEDRE 416
Cdd:PTZ00121 1367 EAAEKKKEEAKKKaDAAKKKAEekKKADEAKKKAEEDKKKADELKKAAAAKKKADeakkkAEEKKKADEAKKKAEEAKKA 1446
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 417 EEIKQIEVYKSHSKFMKTKIDQLKQ--ELSKKESEllalQTKLETLSNQNSDCKQHIEVLKESLTAK----EQRAAILQT 490
Cdd:PTZ00121 1447 DEAKKKAEEAKKAEEAKKKAEEAKKadEAKKKAEE----AKKADEAKKKAEEAKKKADEAKKAAEAKkkadEAKKAEEAK 1522
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 491 EVDALRlRLEEKesflnKKTKQLQDLTEEKGtlAGEIRDMKDMLEVKERKiNVLQKKIENLQEQLRDKDKQLTNLKDRVK 570
Cdd:PTZ00121 1523 KADEAK-KAEEA-----KKADEAKKAEEKKK--ADELKKAEELKKAEEKK-KAEEAKKAEEDKNMALRKAEEAKKAEEAR 1593
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 571 SLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEHA 650
Cdd:PTZ00121 1594 IEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEED 1673
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 651 SSLASAGLKRDSKLKSLEIAIEQKKEECSKLEAQLKKQAEQLfnqmyNPAHNVEDDSRMNPEFADRIKQLDKEASYYRDE 730
Cdd:PTZ00121 1674 KKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEK-----KKAEELKKAEEENKIKAEEAKKEAEEDKKKAEE 1748
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 731 CGKAQAEVDRLLEILKEVENEKNDKDKkiaELESLTLRHMKDQNKKVANLKHNQQLEKKKNAQLLEEVRRREDSMADNSQ 810
Cdd:PTZ00121 1749 AKKDEEEKKKIAHLKKEEEKKAEEIRK---EKEAVIEEELDEEDEKRRMEVDKKIKDIFDNFANIIEGGKEGNLVINDSK 1825
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 811 HL---QIEELMNALEKTRQELDATKARLASTQQSLAE---KEAHLANLRIERRKQLEEILEMKQeallaaISEKDANIAL 884
Cdd:PTZ00121 1826 EMedsAIKEVADSKNMQLEEADAFEKHKFNKNNENGEdgnKEADFNKEKDLKEDDEEEIEEADE------IEKIDKDDIE 1899
|
730 740 750
....*....|....*....|....*....|....*..
gi 1570463013 885 LELSASKKKKTQEEVMALKREKDRLVHQLKQQTQNRM 921
Cdd:PTZ00121 1900 REIPNNNMAGKNNDIIDDKLDKDEYIKRDAEETREEI 1936
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
413-659 |
1.03e-09 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 61.70 E-value: 1.03e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 413 EDREEEIKQIevykshskfmKTKIDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEV 492
Cdd:COG4942 23 AEAEAELEQL----------QQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEI 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 493 DALRLRLEEKESFLNKKTKQLQDL-TEEKGTLAGEIRDMKDMLevkeRKINVLQKKIENLQEQLRDKDKQLTNLKDRVKS 571
Cdd:COG4942 93 AELRAELEAQKEELAELLRALYRLgRQPPLALLLSPEDFLDAV----RRLQYLKYLAPARREQAEELRADLAELAALRAE 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 572 LQTDSsntdTALATLEEALSEKERIIERLKEQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEHAS 651
Cdd:COG4942 169 LEAER----AELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTP 244
|
....*...
gi 1570463013 652 SLASAGLK 659
Cdd:COG4942 245 AAGFAALK 252
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
456-923 |
1.05e-09 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 62.75 E-value: 1.05e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 456 KLETLSNQNSDCKQHIE-VLKESLTAKEQ-RAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDM 533
Cdd:PRK02224 163 KLEEYRERASDARLGVErVLSDQRGSLDQlKAQIEEKEEKDLHERLNGLESELAELDEEIERYEEQREQARETRDEADEV 242
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 534 LEVKERK---INVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQ----TDSSNTDTALATLEEALSEKERIIERLKEQRER 606
Cdd:PRK02224 243 LEEHEERreeLETLEAEIEDLRETIAETEREREELAEEVRDLRerleELEEERDDLLAEAGLDDADAEAVEARREELEDR 322
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 607 DD--RERLEE----IESFRKENKDLKEKVNALQAELTEkesslidLKEHASSLasaglkrDSKLKSLEIAIEQKKEECSK 680
Cdd:PRK02224 323 DEelRDRLEEcrvaAQAHNEEAESLREDADDLEERAEE-------LREEAAEL-------ESELEEAREAVEDRREEIEE 388
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 681 LEAQLKKQAEQlFNQMYNPAHNVEDDSRMNPEFADRIKQLDKEASYYRDECGKAQAEVDRLLEILK------EVENEK-- 752
Cdd:PRK02224 389 LEEEIEELRER-FGDAPVDLGNAEDFLEELREERDELREREAELEATLRTARERVEEAEALLEAGKcpecgqPVEGSPhv 467
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 753 ---NDKDKKIAELESLtLRHMKDQNKKVanlkhNQQLEKKKNAQLLEEVRRREDSMADNSQHLqIEELMNALEKTRQELD 829
Cdd:PRK02224 468 etiEEDRERVEELEAE-LEDLEEEVEEV-----EERLERAEDLVEAEDRIERLEERREDLEEL-IAERRETIEEKRERAE 540
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 830 ATKARLASTQQSLAEKEAHLANLRIERRKQLEEILEMKQEalLAAISEKDANIALLELSASKKKKTQEEVMALkreKDRL 909
Cdd:PRK02224 541 ELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSK--LAELKERIESLERIRTLLAAIADAEDEIERL---REKR 615
|
490
....*....|....
gi 1570463013 910 VHQLKQQTQNRMKL 923
Cdd:PRK02224 616 EALAELNDERRERL 629
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
433-642 |
1.70e-09 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 61.38 E-value: 1.70e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 433 KTKIDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQ 512
Cdd:COG3883 22 QKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALYRSGGS 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 513 LQDLT-----EEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQtdssntdTALATLE 587
Cdd:COG3883 102 VSYLDvllgsESFSDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELE-------AAKAELE 174
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1570463013 588 EALSEKERIIERLKEQRerddRERLEEIESFRKENKDLKEKVNALQAELTEKESS 642
Cdd:COG3883 175 AQQAEQEALLAQLSAEE----AAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAA 225
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
187-878 |
2.89e-09 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 61.52 E-value: 2.89e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 187 SPELKKERVLRKEEAARMSVLKEQMRVS-HEENQHLQLTIQALQDELRTQRDLNHLLQQESgnrgaehftiELTEENFRR 265
Cdd:TIGR00618 189 KKSLHGKAELLTLRSQLLTLCTPCMPDTyHERKQVLEKELKHLREALQQTQQSHAYLTQKR----------EAQEEQLKK 258
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 266 LQA--EHDRQAKELFLLRKTLEEMELRIETQKQTLNARDES---------IKKLLEMLQSK-GLPSKSLEDDNERTRRMA 333
Cdd:TIGR00618 259 QQLlkQLRARIEELRAQEAVLEETQERINRARKAAPLAAHIkavtqieqqAQRIHTELQSKmRSRAKLLMKRAAHVKQQS 338
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 334 EAESQVSHLEVILDQKEKENIHLREELHRRSQLQPEPAKTKALQTVIEMK--DTKIASLERNIRDLEDEIQmlkanGVLN 411
Cdd:TIGR00618 339 SIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQHIHTLQQQKttLTQKLQSLCKELDILQREQ-----ATID 413
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 412 TEDREEEIKQIEVYKSHSKF-MKTKIDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRaaiLQT 490
Cdd:TIGR00618 414 TRTSAFRDLQGQLAHAKKQQeLQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQETR---KKA 490
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 491 EVDALRLRLEEKESFLNKKTKQLqdltEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVK 570
Cdd:TIGR00618 491 VVLARLLELQEEPCPLCGSCIHP----NPARQDIDNPGPLTRRMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQ 566
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 571 SLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRERLEEIESFRKENKDLKEKVNALQAELTE--KESSLIDLKE 648
Cdd:TIGR00618 567 EIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQPEQDLQDVRLHLqqCSQELALKLT 646
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 649 HASSLASAGLKRDSKLKSLEIAiEQKKEECSKLEAQLKKqAEQLFNQMYNPAHNVEDDSRMNPEFADRIKQLDKEASYYR 728
Cdd:TIGR00618 647 ALHALQLTLTQERVREHALSIR-VLPKELLASRQLALQK-MQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIE 724
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 729 DECGKAQAEVDRLLEILKEVENEKNDKDKKiaELESLTLRHMKDQNKKVANLKHNQQLE------KKKNAQLLEEVRRRE 802
Cdd:TIGR00618 725 NASSSLGSDLAAREDALNQSLKELMHQART--VLKARTEAHFNNNEEVTAALQTGAELShlaaeiQFFNRLREEDTHLLK 802
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1570463013 803 DSMADNSQHLQIEELMNAL--EKTRQELDATKARLASTQQSLAEKEAHLANLRiERRKQLEEIleMKQEALLAAISEK 878
Cdd:TIGR00618 803 TLEAEIGQEIPSDEDILNLqcETLVQEEEQFLSRLEEKSATLGEITHQLLKYE-ECSKQLAQL--TQEQAKIIQLSDK 877
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
375-610 |
3.34e-09 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 60.16 E-value: 3.34e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 375 ALQTVIEMKDTKIASLERNIRDLEDEIQMLKANgvlnTEDREEEIKQIEvykshskfmkTKIDQLKQELSKKESELLALQ 454
Cdd:COG4942 17 AQADAAAEAEAELEQLQQEIAELEKELAALKKE----EKALLKQLAALE----------RRIAALARRIRALEQELAALE 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 455 TKLETLSNQNSDCKQHIEVLKESLtAKEQRAAILQTEVDALRLRLEEKESF-LNKKTKQLQDLTEEKGTLAGEIRDMKDM 533
Cdd:COG4942 83 AELAELEKEIAELRAELEAQKEEL-AELLRALYRLGRQPPLALLLSPEDFLdAVRRLQYLKYLAPARREQAEELRADLAE 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 534 LEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDR----VKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDR 609
Cdd:COG4942 162 LAALRAELEAERAELEALLAELEEERAALEALKAErqklLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAE 241
|
.
gi 1570463013 610 E 610
Cdd:COG4942 242 R 242
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
148-639 |
4.04e-09 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 61.08 E-value: 4.04e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 148 LDLQAQLKELQRENDLLRKELDIKDSKLGSSMNSIKtfwspELKKERVLRKEEAARmsvLKEQMR-VSHEENQHLQLTIQ 226
Cdd:COG4913 277 LRAALRLWFAQRRLELLEAELEELRAELARLEAELE-----RLEARLDALREELDE---LEAQIRgNGGDRLEQLEREIE 348
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 227 ALQDELRTQRdlNHLLQQESGNRGAeHFTIELTEENFRRLQAEHDRQAKELFLLRKTLEEMELRIETQKQTLNARDESIK 306
Cdd:COG4913 349 RLERELEERE--RRRARLEALLAAL-GLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELE 425
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 307 KLLEMLQSKGlpsKSLEDDNERTRRMAEAESQVS---------HLEVILDQK------EK-------------------- 351
Cdd:COG4913 426 AEIASLERRK---SNIPARLLALRDALAEALGLDeaelpfvgeLIEVRPEEErwrgaiERvlggfaltllvppehyaaal 502
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 352 ---ENIHLREELH------RRSQLQPEPAKTKALQTVIEMKDTKI-----ASLER--------NIRDLEDEIQ------M 403
Cdd:COG4913 503 rwvNRLHLRGRLVyervrtGLPDPERPRLDPDSLAGKLDFKPHPFrawleAELGRrfdyvcvdSPEELRRHPRaitragQ 582
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 404 LKANGVLNTEDREEEIKQIEVYKSHSKfmkTKIDQLKQELSKKESELLALQTKLETLsnqnsdcKQHIEVLKESLTAKEQ 483
Cdd:COG4913 583 VKGNGTRHEKDDRRRIRSRYVLGFDNR---AKLAALEAELAELEEELAEAEERLEAL-------EAELDALQERREALQR 652
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 484 RAAILQTEVD--ALRLRLEEKEsflnkktKQLQDLTEEKGTLAGeirdMKDMLEVKERKINVLQKKIENLQEQLRDKDKQ 561
Cdd:COG4913 653 LAEYSWDEIDvaSAEREIAELE-------AELERLDASSDDLAA----LEEQLEELEAELEELEEELDELKGEIGRLEKE 721
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1570463013 562 LTNLKDRVKSLQTDSSNTDTALATLEEALSEkERIIERLKEQRERDDRERLEEiesfrkENKDLKEKVNALQAELTEK 639
Cdd:COG4913 722 LEQAEEELDELQDRLEAAEDLARLELRALLE-ERFAAALGDAVERELRENLEE------RIDALRARLNRAEEELERA 792
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
432-631 |
5.56e-09 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 58.01 E-value: 5.56e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 432 MKTKIDQLKqELSKKESELLALQTKLETLsnqnsdcKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLnkktK 511
Cdd:COG1579 2 MPEDLRALL-DLQELDSELDRLEHRLKEL-------PAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEI----E 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 512 QLQDLTEEKGTLAGEIRDMKDMlevkerkiNVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQtdssntdTALATLEEALS 591
Cdd:COG1579 70 EVEARIKKYEEQLGNVRNNKEY--------EALQKEIESLKRRISDLEDEILELMERIEELE-------EELAELEAELA 134
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 1570463013 592 EKERIIERLKEQRERDDRERLEEIESFRKENKDLKEKVNA 631
Cdd:COG1579 135 ELEAELEEKKAELDEELAELEAELEELEAEREELAAKIPP 174
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
538-692 |
5.87e-09 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 58.01 E-value: 5.87e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 538 ERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQ-------RERDDRE 610
Cdd:COG1579 16 DSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQlgnvrnnKEYEALQ 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 611 RleEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASaglKRDSKLKSLEIAIEQKKEECSKLEAQLKKQAE 690
Cdd:COG1579 96 K--EIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEA---ELEEKKAELDEELAELEAELEELEAEREELAA 170
|
..
gi 1570463013 691 QL 692
Cdd:COG1579 171 KI 172
|
|
| MAD |
pfam05557 |
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ... |
145-605 |
1.05e-08 |
|
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.
Pssm-ID: 461677 [Multi-domain] Cd Length: 660 Bit Score: 59.37 E-value: 1.05e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 145 STMLDLQAQLKELQRENDLLRKELDIKDSKLGSSMNSIKTFWSPELKKERVLRKEEAARMSVLKEQMRVSHEENQHLQLT 224
Cdd:pfam05557 9 ARLSQLQNEKKQMELEHKRARIELEKKASALKRQLDRESDRNQELQKRIRLLEKREAEAEEALREQAELNRLKKKYLEAL 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 225 IQALQDELRTQRDLNHLLQQESGNRGAEHFTIELTEENFRRLQAEHDRQAKELFLLRKTLEEMELRI---ETQKQTLNAR 301
Cdd:pfam05557 89 NKKLNEKESQLADAREVISCLKNELSELRRQIQRAELELQSTNSELEELQERLDLLKAKASEAEQLRqnlEKQQSSLAEA 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 302 DESIKKLLEMLQSKglpskslEDDNERTRRMAEAESQVSHLEVILDQKEKENIHLREELHRRSQLQPEPAKTKALQTVIE 381
Cdd:pfam05557 169 EQRIKELEFEIQSQ-------EQDSEIVKNSKSELARIPELEKELERLREHNKHLNENIENKLLLKEEVEDLKRKLEREE 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 382 MKDTKIASLERNIRDLEDEIQM---LKANGVLNTEDREEEIKQIEVYKSHSKFMKTKIDQLKQELSKKESELLALQTKLE 458
Cdd:pfam05557 242 KYREEAATLELEKEKLEQELQSwvkLAQDTGLNLRSPEDLSRRIEQLQQREIVLKEENSSLTSSARQLEKARRELEQELA 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 459 TLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNkKTKQLQDLTEEKGTLAGEIRDMKDMLEVKE 538
Cdd:pfam05557 322 QYLKKIEDLNKKLKRHKALVRRLQRRVLLLTKERDGYRAILESYDKELT-MSNYSPQLLERIEEAEDMTQKMQAHNEEME 400
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1570463013 539 RKINVLQKKIENLQEQLRDKDKQLTNLKDrvKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRE 605
Cdd:pfam05557 401 AQLSVAEEELGGYKQQAQTLERELQALRQ--QESLADPSYSKEEVDSLRRKLETLELERQRLREQKN 465
|
|
| HEC1 |
COG5185 |
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ... |
368-719 |
1.09e-08 |
|
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 444066 [Multi-domain] Cd Length: 594 Bit Score: 59.20 E-value: 1.09e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 368 PEPAKTKALQTVIEMKDTKIASLerNIRDLEDEIQMLKANGVLntEDREEEIKQIEVYKSHSKFMKTKIDQLKQELSKKE 447
Cdd:COG5185 198 AEPSGTVNSIKESETGNLGSEST--LLEKAKEIINIEEALKGF--QDPESELEDLAQTSDKLEKLVEQNTDLRLEKLGEN 273
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 448 SEllalqtKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQT--EVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAG 525
Cdd:COG5185 274 AE------SSKRLNENANNLIKQFENTKEKIAEYTKSIDIKKAteSLEEQLAAAEAEQELEESKRETETGIQNLTAEIEQ 347
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 526 EIRDMKDMLEV--KERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSN-TDTALATLEEALSEKERIIERLKE 602
Cdd:COG5185 348 GQESLTENLEAikEEIENIVGEVELSKSSEELDSFKDTIESTKESLDEIPQNQRGyAQEILATLEDTLKAADRQIEELQR 427
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 603 QRERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESSliDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEECSKLE 682
Cdd:COG5185 428 QIEQATSSNEEVSKLLNELISELNKVMREADEESQSRLEE--AYDEINRSVRSKKEDLNEELTQIESRVSTLKATLEKLR 505
|
330 340 350
....*....|....*....|....*....|....*..
gi 1570463013 683 AQLKKQAEQLFNQMYNPAHNVEDDSRMNPEFADRIKQ 719
Cdd:COG5185 506 AKLERQLEGVRSKLDQVAESLKDFMRARGYAHILALE 542
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
151-826 |
1.29e-08 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 59.68 E-value: 1.29e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 151 QAQLKELQRENDLLRKELDIKDSKLGSSMNS----IKTFWSPELKKERVLRKEEAARMSVLKEQMRVSHEENQHLQLTIQ 226
Cdd:TIGR00606 425 QEQADEIRDEKKGLGRTIELKKEILEKKQEElkfvIKELQQLEGSSDRILELDQELRKAERELSKAEKNSLTETLKKEVK 504
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 227 ALQDE----LRTQRDLNHLLQQESGNRGAEHFTIELTEENFRRLQAEHDRQAKELFLLRKTLEEMELRIETQKqTLNARD 302
Cdd:TIGR00606 505 SLQNEkadlDRKLRKLDQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLLGYFPNKKQLED-WLHSKS 583
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 303 ESIKKLLEMLQSKGLPSKSLEDDNERTRRMAEA-ESQVSHLEVIL------DQKEKENIHLREELHR-RSQLQPEPAKTK 374
Cdd:TIGR00606 584 KEINQTRDRLAKLNKELASLEQNKNHINNELESkEEQLSSYEDKLfdvcgsQDEESDLERLKEEIEKsSKQRAMLAGATA 663
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 375 ALQTVIEMKDTKIAS-------LERNIRDLEDEIQMLKANGVLNTEDREEEIKQIEVYKSHSKFMKTKIDQLKQELSKKE 447
Cdd:TIGR00606 664 VYSQFITQLTDENQSccpvcqrVFQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKE 743
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 448 SELLALQTKLETLSNQNSDCKQHI---EVLKESLTAKEQRAAILQTEV---DALRLRLEEKESFLNKKTKQLQ--DLTEE 519
Cdd:TIGR00606 744 KEIPELRNKLQKVNRDIQRLKNDIeeqETLLGTIMPEEESAKVCLTDVtimERFQMELKDVERKIAQQAAKLQgsDLDRT 823
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 520 KGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIER 599
Cdd:TIGR00606 824 VQQVNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIRE 903
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 600 LKEQR----------ERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKrdsklkslei 669
Cdd:TIGR00606 904 IKDAKeqdspletflEKDQQEKEELISSKETSNKKAQDKVNDIKEKVKNIHGYMKDIENKIQDGKDDYLK---------- 973
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 670 aieQKKEECSKLEAQLKKqaeqlfnqmynpahNVEDDSRMNPEFadRIKQLDKEASYYRDECGKAQAEVDRLLEILKEVE 749
Cdd:TIGR00606 974 ---QKETELNTVNAQLEE--------------CEKHQEKINEDM--RLMRQDIDTQKIQERWLQDNLTLRKRENELKEVE 1034
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1570463013 750 NEKNDKDKKIAELESLtlrHMKDQNKKvanLKHNQQLEKKKNAQLLEEVRRREDSMADNSQHLQIEELMNALEKTRQ 826
Cdd:TIGR00606 1035 EELKQHLKEMGQMQVL---QMKQEHQK---LEENIDLIKRNHVLALGRQKGYEKEIKHFKKELREPQFRDAEEKYRE 1105
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
162-651 |
1.67e-08 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 58.63 E-value: 1.67e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 162 DLLRKELDIKDSKLGSSMNSIKTFWSPELKKERVLRKEEAARmsvlkeqmrvsHEENQHLQLTIQALQDELRTQRDLNHL 241
Cdd:COG4717 45 AMLLERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEK-----------EEEYAELQEELEELEEELEELEAELEE 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 242 LQQESGN--RGAEHFTIELTEENFRRLQAEHDRQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEmlqskGLPS 319
Cdd:COG4717 114 LREELEKleKLLQLLPLYQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLE-----QLSL 188
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 320 KSLEDDNERTRRMAEAESQVSHLEVILDQKEKENIHLREELHRRSQLQPEPAKTKALQT------------VIEMKDTKI 387
Cdd:COG4717 189 ATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEarlllliaaallALLGLGGSL 268
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 388 ASLERNIRDLEDEIQMLKANGVL----NTEDREEEIKQIEVYKSHSKFMKTKIDQLKQELSKKE----SELLALQTKLET 459
Cdd:COG4717 269 LSLILTIAGVLFLVLGLLALLFLllarEKASLGKEAEELQALPALEELEEEELEELLAALGLPPdlspEELLELLDRIEE 348
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 460 LSNQNSDCKQHIEVLKESLTAKEQRAAILQTEV---DALRLRLEEKESFLNKKtKQLQDLTEEKGTLAGEIRDMKDMLEV 536
Cdd:COG4717 349 LQELLREAEELEEELQLEELEQEIAALLAEAGVedeEELRAALEQAEEYQELK-EELEELEEQLEELLGELEELLEALDE 427
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 537 KErkinvLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTAlATLEEALSEKERIIERLKEQRERDDRERL---- 612
Cdd:COG4717 428 EE-----LEEELEELEEELEELEEELEELREELAELEAELEQLEED-GELAELLQELEELKAELRELAEEWAALKLalel 501
|
490 500 510 520
....*....|....*....|....*....|....*....|..
gi 1570463013 613 --EEIESFRKENKD-LKEKVNALQAELTEKESSLIDLKEHAS 651
Cdd:COG4717 502 leEAREEYREERLPpVLERASEYFSRLTDGRYRLIRIDEDLS 543
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
381-813 |
1.68e-08 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 59.29 E-value: 1.68e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 381 EMKDTKIASLERNIRDLEDEIQMLkangvlnTEDREEEIKQIEVYKSHSKFMKTkIDQLKQELSKKESEllalQTKLETL 460
Cdd:TIGR01612 879 EISDDKLNDYEKKFNDSKSLINEI-------NKSIEEEYQNINTLKKVDEYIKI-CENTKESIEKFHNK----QNILKEI 946
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 461 SNQNSDCKQHIEVLKESLTAKEQRAAILQ-TEVDAL--RLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIrdMKDMLEVK 537
Cdd:TIGR01612 947 LNKNIDTIKESNLIEKSYKDKFDNTLIDKiNELDKAfkDASLNDYEAKNNELIKYFNDLKANLGKNKENM--LYHQFDEK 1024
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 538 ERKINVLQKKIENLQEQLRDKD----KQLTNLKDRVKSL---QTDSSNTDTaLATLEEALSEKERIIERLKEQRERD--- 607
Cdd:TIGR01612 1025 EKATNDIEQKIEDANKNIPNIEiaihTSIYNIIDEIEKEigkNIELLNKEI-LEEAEINITNFNEIKEKLKHYNFDDfgk 1103
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 608 --DRERLEEIESFRKENKDLKEKVNALQAELTE----KESSLIDLKEHASSLASAGLKR---------DSKLKSLEIAIE 672
Cdd:TIGR01612 1104 eeNIKYADEINKIKDDIKNLDQKIDHHIKALEEikkkSENYIDEIKAQINDLEDVADKAisnddpeeiEKKIENIVTKID 1183
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 673 QKK---EECSKLEAQLKKQAEQLFNQMYNPAHNVEDDSRMNPEFADRIKQLDKEASYYRDECGKAQAEVDRLLEILKEVE 749
Cdd:TIGR01612 1184 KKKniyDEIKKLLNEIAEIEKDKTSLEEVKGINLSYGKNLGKLFLEKIDEEKKKSEHMIKAMEAYIEDLDEIKEKSPEIE 1263
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1570463013 750 NEKNDKDKKIAELESLTLRHMKDQNKKVANLKHNQQLEKKKNAQL-LEEVRRREDSMADNSQHLQ 813
Cdd:TIGR01612 1264 NEMGIEMDIKAEMETFNISHDDDKDHHIISKKHDENISDIREKSLkIIEDFSEESDINDIKKELQ 1328
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
265-638 |
2.00e-08 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 58.93 E-value: 2.00e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 265 RLQAEHDRQAKELFLLRKTLEEMELRIET---QKQTLNARDESIKKLLEMLQSKglpSKSLEddnertRRMAEAESQVSH 341
Cdd:TIGR02169 692 SLQSELRRIENRLDELSQELSDASRKIGEiekEIEQLEQEEEKLKERLEELEED---LSSLE------QEIENVKSELKE 762
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 342 LEVILDQKEKENIHLREELH------RRSQLQPEPAKTKALQTVIEMKDTKIASLERNIRD-------LEDEIQMLKANg 408
Cdd:TIGR02169 763 LEARIEELEEDLHKLEEALNdlearlSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRltlekeyLEKEIQELQEQ- 841
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 409 VLNTEDREEEIKQievykshskfmktkidqlkqelskkesellalqtkletlsnqnsdckqhievlkesltakeqraail 488
Cdd:TIGR02169 842 RIDLKEQIKSIEK------------------------------------------------------------------- 854
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 489 qtEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDR 568
Cdd:TIGR02169 855 --EIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEE 932
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 569 VKSLqtdssntDTALATLEEaLSEKERIIERLKEQRERDDRE----------RLEEIESFRKENKDLKEKVNALQAELTE 638
Cdd:TIGR02169 933 LSEI-------EDPKGEDEE-IPEEELSLEDVQAELQRVEEEiralepvnmlAIQEYEEVLKRLDELKEKRAKLEEERKA 1004
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
224-737 |
2.00e-08 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 58.77 E-value: 2.00e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 224 TIQALQDELRTQRDLNHLLQQESGNRGAEHFTIELT--EENFRRLQAEHDRQAKELFLLRKTLEEMELRIETQKqtlNAR 301
Cdd:COG4913 263 RYAAARERLAELEYLRAALRLWFAQRRLELLEAELEelRAELARLEAELERLEARLDALREELDELEAQIRGNG---GDR 339
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 302 DESIKKLLEMLQskglpskslEDDNERTRRMAEAESQVSHLEVILDQKEKENIHLREELHRRsqLQPEPAKTKALQTVIE 381
Cdd:COG4913 340 LEQLEREIERLE---------RELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAAL--LEALEEELEALEEALA 408
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 382 MKDTKIASLERNIRDLEDEIQMLKANGVlNTEDREEEIKqievykshskfmktkiDQLKQELSKKESEL----------- 450
Cdd:COG4913 409 EAEAALRDLRRELRELEAEIASLERRKS-NIPARLLALR----------------DALAEALGLDEAELpfvgelievrp 471
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 451 ------LALQTKLETLS-----------------NQNSDcKQHIEVLKESLTAKEQRAAilQTEVDALRLRLEEKES--- 504
Cdd:COG4913 472 eeerwrGAIERVLGGFAltllvppehyaaalrwvNRLHL-RGRLVYERVRTGLPDPERP--RLDPDSLAGKLDFKPHpfr 548
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 505 -FLNKKTKQLQDL----------TEEKG-TLAGEIRDMKDMLEVK---------------ERKINVLQKKIENLQEQLRD 557
Cdd:COG4913 549 aWLEAELGRRFDYvcvdspeelrRHPRAiTRAGQVKGNGTRHEKDdrrrirsryvlgfdnRAKLAALEAELAELEEELAE 628
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 558 KDKQLTNLKDRVKSLQTDSSntdtALATLEEALsekERIIERLKEQRERDD-RERLEEIESFRKENKDLKEKVNALQAEL 636
Cdd:COG4913 629 AEERLEALEAELDALQERRE----ALQRLAEYS---WDEIDVASAEREIAElEAELERLDASSDDLAALEEQLEELEAEL 701
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 637 TEKESSLIDLKEHASSLasaglkrDSKLKSLEIAIEQKKEECSKLEAQLKKQAEQLFNQMYNPAHNVEDDSRMNPEFADR 716
Cdd:COG4913 702 EELEEELDELKGEIGRL-------EKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVERELRENLEER 774
|
570 580
....*....|....*....|.
gi 1570463013 717 IKQLDKEASYYRDECGKAQAE 737
Cdd:COG4913 775 IDALRARLNRAEEELERAMRA 795
|
|
| MAD |
pfam05557 |
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ... |
433-842 |
2.04e-08 |
|
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.
Pssm-ID: 461677 [Multi-domain] Cd Length: 660 Bit Score: 58.60 E-value: 2.04e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 433 KTKIDQLKQELSKKE-----------SELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEE 501
Cdd:pfam05557 8 KARLSQLQNEKKQMElehkrarieleKKASALKRQLDRESDRNQELQKRIRLLEKREAEAEEALREQAELNRLKKKYLEA 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 502 KESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDT 581
Cdd:pfam05557 88 LNKKLNEKESQLADAREVISCLKNELSELRRQIQRAELELQSTNSELEELQERLDLLKAKASEAEQLRQNLEKQQSSLAE 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 582 A---LATLEEALSEKERIIERLKEQRERDDR--------ERLEEIESFRKENKD----LKEKVNALQAELTEKEssliDL 646
Cdd:pfam05557 168 AeqrIKELEFEIQSQEQDSEIVKNSKSELARipelekelERLREHNKHLNENIEnkllLKEEVEDLKRKLEREE----KY 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 647 KEHASSLASAGLKRDSKLKSLEIAIEQKKEECSKLEAqLKKQAEQLfnQMYNPAHNVEDDSRMNpefadRIKQLDKEASY 726
Cdd:pfam05557 244 REEAATLELEKEKLEQELQSWVKLAQDTGLNLRSPED-LSRRIEQL--QQREIVLKEENSSLTS-----SARQLEKARRE 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 727 YRDECGKAQAEVDRLLEILKEVENEKNDKDKKIAELEsltlrhmKDQNKKVANLKH--NQQLEKKKNAQLLEEVRRREDS 804
Cdd:pfam05557 316 LEQELAQYLKKIEDLNKKLKRHKALVRRLQRRVLLLT-------KERDGYRAILESydKELTMSNYSPQLLERIEEAEDM 388
|
410 420 430
....*....|....*....|....*....|....*...
gi 1570463013 805 MADnsQHLQIEELMNALEKTRQELDATKARLASTQQSL 842
Cdd:pfam05557 389 TQK--MQAHNEEMEAQLSVAEEELGGYKQQAQTLEREL 424
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
273-524 |
2.42e-08 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 57.47 E-value: 2.42e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 273 QAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLqskglpsKSLEDD-NERTRRMAEAESQVSHLEVILDQKEK 351
Cdd:COG4942 18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQL-------AALERRiAALARRIRALEQELAALEAELAELEK 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 352 ENIHLREELHRRSQLQpepakTKALQTVIEMKDTKIASLERNIRDLEDEIQMLKANGVLNTEDREeeikQIEVYKSHSKF 431
Cdd:COG4942 91 EIAELRAELEAQKEEL-----AELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARRE----QAEELRADLAE 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 432 MKTKIDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLE--EKESFLNKK 509
Cdd:COG4942 162 LAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIArlEAEAAAAAE 241
|
250
....*....|....*
gi 1570463013 510 TKQLQDLTEEKGTLA 524
Cdd:COG4942 242 RTPAAGFAALKGKLP 256
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
346-595 |
2.60e-08 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 57.47 E-value: 2.60e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 346 LDQKEKENIHLREELHR-RSQLQPEPAKTKALQTVIEMKDTKIASLERNIRDLEDEIQMLkangvlntedrEEEIKQIEv 424
Cdd:COG4942 22 AAEAEAELEQLQQEIAElEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAAL-----------EAELAELE- 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 425 ykshskfmkTKIDQLKQELSKKESELLALQTKLETLSNQNSdckqhIEVL--KESLTAKEQRAAILQTEVDALRLRLEEk 502
Cdd:COG4942 90 ---------KEIAELRAELEAQKEELAELLRALYRLGRQPP-----LALLlsPEDFLDAVRRLQYLKYLAPARREQAEE- 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 503 esfLNKKTKQLQDLTEEkgtLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTA 582
Cdd:COG4942 155 ---LRADLAELAALRAE---LEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEAL 228
|
250
....*....|...
gi 1570463013 583 LATLEEALSEKER 595
Cdd:COG4942 229 IARLEAEAAAAAE 241
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
423-925 |
2.78e-08 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 58.59 E-value: 2.78e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 423 EVYKSHSKFMKTKIDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTA----KEQRAAILQTEVDALRLR 498
Cdd:pfam15921 99 ELHEKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTVHELEAakclKEDMLEDSNTQIEQLRKM 178
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 499 LEEKESFLNKKTKQLQDLTEEKGTlagEIRDMKDMLEVKERKINVLQKKIenlqeqLRDKDKQLTNLKDRVKSLQTDssn 578
Cdd:pfam15921 179 MLSHEGVLQEIRSILVDFEEASGK---KIYEHDSMSTMHFRSLGSAISKI------LRELDTEISYLKGRIFPVEDQ--- 246
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 579 tdtalatLEEALSEKERIIERLKEQRErddrERLEE-IESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAG 657
Cdd:pfam15921 247 -------LEALKSESQNKIELLLQQHQ----DRIEQlISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQARNQNSMY 315
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 658 LKrdsKLKSLEIAIEQKKEECSKLEAQLKKQAEQLFNQMynpahnVEDDSRMNPEFADRiKQLDKEASYYRDECGKAQAE 737
Cdd:pfam15921 316 MR---QLSDLESTVSQLRSELREAKRMYEDKIEELEKQL------VLANSELTEARTER-DQFSQESGNLDDQLQKLLAD 385
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 738 V-DRLLEILKEVENEKNDKDKKIAEleSLTLRHMK----DQNKKVANLkhnQQLEKKKNAQLLEEVRRREDSMADNSQHL 812
Cdd:pfam15921 386 LhKREKELSLEKEQNKRLWDRDTGN--SITIDHLRreldDRNMEVQRL---EALLKAMKSECQGQMERQMAAIQGKNESL 460
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 813 --------QIEELMNALEKTRQELDATKARLASTQQSLAEKEAHLanlriERRKQLEEILEMKQEALLAAISEKDANIAL 884
Cdd:pfam15921 461 ekvssltaQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASL-----QEKERAIEATNAEITKLRSRVDLKLQELQH 535
|
490 500 510 520
....*....|....*....|....*....|....*....|....
gi 1570463013 885 LELSASKKKKTQEEVMALK---REKDRLVHQLKQQTQNRMKLMA 925
Cdd:pfam15921 536 LKNEGDHLRNVQTECEALKlqmAEKDKVIEILRQQIENMTQLVG 579
|
|
| 46 |
PHA02562 |
endonuclease subunit; Provisional |
417-628 |
2.80e-08 |
|
endonuclease subunit; Provisional
Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 58.10 E-value: 2.80e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 417 EEIKQIEVYKSHSKFMKTKIDQLKQELSKKESELLALQTKLET----------LSNQNSDCKQHI--EVLKESLTAKEQR 484
Cdd:PHA02562 157 EDLLDISVLSEMDKLNKDKIRELNQQIQTLDMKIDHIQQQIKTynknieeqrkKNGENIARKQNKydELVEEAKTIKAEI 236
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 485 AAiLQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGE----------------IRDMKDMLEVKERKINVLQKKI 548
Cdd:PHA02562 237 EE-LTDELLNLVMDIEDPSAALNKLNTAAAKIKSKIEQFQKVikmyekggvcptctqqISEGPDRITKIKDKLKELQHSL 315
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 549 ENL---QEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDrerlEEIESFRKENKDL 625
Cdd:PHA02562 316 EKLdtaIDELEEIMDEFNEQSKKLLELKNKISTNKQSLITLVDKAKKVKAAIEELQAEFVDNA----EELAKLQDELDKI 391
|
...
gi 1570463013 626 KEK 628
Cdd:PHA02562 392 VKT 394
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
510-692 |
3.93e-08 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 57.08 E-value: 3.93e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 510 TKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEA 589
Cdd:COG4942 19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 590 LSE-KERIIERLKEQRERDDRERLEEIES-------------FRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLAS 655
Cdd:COG4942 99 LEAqKEELAELLRALYRLGRQPPLALLLSpedfldavrrlqyLKYLAPARREQAEELRADLAELAALRAELEAERAELEA 178
|
170 180 190
....*....|....*....|....*....|....*..
gi 1570463013 656 AGLKRDSKLKSLEIAIEQKKEECSKLEAQLKKQAEQL 692
Cdd:COG4942 179 LLAELEEERAALEALKAERQKLLARLEKELAELAAEL 215
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
511-764 |
3.98e-08 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 58.00 E-value: 3.98e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 511 KQLQDLTEEkgtlageIRDMkdMLEVKErkinvLQKKIENLQEQLRDKD---KQLTNLKDRVKSLQtDSSNTDTALATLE 587
Cdd:COG4913 204 KPIGDLDDF-------VREY--MLEEPD-----TFEAADALVEHFDDLErahEALEDAREQIELLE-PIRELAERYAAAR 268
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 588 EALSEKERIIERLK-EQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEhasSLASAGLKRdskLKS 666
Cdd:COG4913 269 ERLAELEYLRAALRlWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEA---QIRGNGGDR---LEQ 342
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 667 LEIAIEQKKEECSKLEAQLKKQAEQLFNQMYNPAHNVEddsrmnpEFADRIKQLDKEASYYRDECGKAQAEVDRLLEILK 746
Cdd:COG4913 343 LEREIERLERELEERERRRARLEALLAALGLPLPASAE-------EFAALRAEAAALLEALEEELEALEEALAEAEAALR 415
|
250
....*....|....*...
gi 1570463013 747 EVENEKNDKDKKIAELES 764
Cdd:COG4913 416 DLRRELRELEAEIASLER 433
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
614-847 |
4.04e-08 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 56.76 E-value: 4.04e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 614 EIESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEECSKLEAQLKKQAEQLF 693
Cdd:COG3883 17 QIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALY 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 694 NQMYNPAH-NVEDDSRMNPEFADRIKQLDKEASYYRDEcgkaqaeVDRLLEILKEVENEKNDKDKKIAELESLTlrhmKD 772
Cdd:COG3883 97 RSGGSVSYlDVLLGSESFSDFLDRLSALSKIADADADL-------LEELKADKAELEAKKAELEAKLAELEALK----AE 165
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1570463013 773 QNKKVANLKHNQQLEKKKNAQLLEEVRRREDSMADNSQhlQIEELMNALEKTRQELDATKARLASTQQSLAEKEA 847
Cdd:COG3883 166 LEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEA--ELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAA 238
|
|
| 46 |
PHA02562 |
endonuclease subunit; Provisional |
205-444 |
4.77e-08 |
|
endonuclease subunit; Provisional
Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 57.33 E-value: 4.77e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 205 SVLKEQMRVSHEENQHLQLTIQALQDELRTQRDLNHLLQQESGNRGAEHFTI--ELTEENfRRLQAEHDRQAKELFLLRK 282
Cdd:PHA02562 170 KLNKDKIRELNQQIQTLDMKIDHIQQQIKTYNKNIEEQRKKNGENIARKQNKydELVEEA-KTIKAEIEELTDELLNLVM 248
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 283 TLEEME---LRIETQKQTLNARDESIKKLLEMLQSKGLPSKSLEDDNERTRRMAEAESQVSHLEVILdqkEKENIHLREE 359
Cdd:PHA02562 249 DIEDPSaalNKLNTAAAKIKSKIEQFQKVIKMYEKGGVCPTCTQQISEGPDRITKIKDKLKELQHSL---EKLDTAIDEL 325
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 360 LHRRSQLQPEPAKTKALQTVIEMKDTKIASLERNIRDLEDEIQMLKANGVlnteDREEEIKQIEVYKSHSKFMKTKIDQL 439
Cdd:PHA02562 326 EEIMDEFNEQSKKLLELKNKISTNKQSLITLVDKAKKVKAAIEELQAEFV----DNAEELAKLQDELDKIVKTKSELVKE 401
|
....*
gi 1570463013 440 KQELS 444
Cdd:PHA02562 402 KYHRG 406
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
149-553 |
5.04e-08 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 57.76 E-value: 5.04e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 149 DLQAQLKELQRENDLLRKELDIKDSKLGSSMNSIKTFWSPELKKERVLRKEEAARMSvLKEQMRVSHEENQHLQLTIQAL 228
Cdd:TIGR02168 702 ELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTE-LEAEIEELEERLEEAEEELAEA 780
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 229 QDELRTqrdlnhlLQQESGNRGAEHFTIeltEENFRRLQAEHDRQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKL 308
Cdd:TIGR02168 781 EAEIEE-------LEAQIEQLKEELKAL---REALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEEL 850
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 309 LEMLQSKglpSKSLEDDNErtrRMAEAESQvshLEVILDQKEKENIHLREELHRRSQLqpepaktkalqtviemkDTKIA 388
Cdd:TIGR02168 851 SEDIESL---AAEIEELEE---LIEELESE---LEALLNERASLEEALALLRSELEEL-----------------SEELR 904
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 389 SLERNIRDLEDEIQMLKangvlntedreEEIKQIEvykshskfmkTKIDQLKQElskkesellaLQTKLETLSNQNSDCK 468
Cdd:TIGR02168 905 ELESKRSELRRELEELR-----------EKLAQLE----------LRLEGLEVR----------IDNLQERLSEEYSLTL 953
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 469 QHIEVLKESLTAKEQRAailQTEVDALRLRL--------------EEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDml 534
Cdd:TIGR02168 954 EEAEALENKIEDDEEEA---RRRLKRLENKIkelgpvnlaaieeyEELKERYDFLTAQKEDLTEAKETLEEAIEEIDR-- 1028
|
410
....*....|....*....
gi 1570463013 535 EVKERKINVLQKKIENLQE 553
Cdd:TIGR02168 1029 EARERFKDTFDQVNENFQR 1047
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
752-869 |
5.68e-08 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 56.71 E-value: 5.68e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 752 KNDKDKKIAELESLTLRHMKDQNKKVANLKHNQQLE-----KKKNAQLLEEVRRREDSMADNSQHLQIEEL-----MNAL 821
Cdd:PRK12704 26 KKIAEAKIKEAEEEAKRILEEAKKEAEAIKKEALLEakeeiHKLRNEFEKELRERRNELQKLEKRLLQKEEnldrkLELL 105
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 1570463013 822 EKTRQELDATKARLASTQQSLAEKEAHLANLRIERRKQLEEILEMKQE 869
Cdd:PRK12704 106 EKREEELEKKEKELEQKQQELEKKEEELEELIEEQLQELERISGLTAE 153
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
487-914 |
9.22e-08 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 56.61 E-value: 9.22e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 487 ILQTEVDALRLRLEEKESFLnKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKInvlqKKIENLQEQLRDKDKQLTNLK 566
Cdd:PRK03918 132 IRQGEIDAILESDESREKVV-RQILGLDDYENAYKNLGEVIKEIKRRIERLEKFI----KRTENIEELIKEKEKELEEVL 206
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 567 DRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQR-------------ERDDRERLEEIESFRKENKDLKEKVNALQ 633
Cdd:PRK03918 207 REINEISSELPELREELEKLEKEVKELEELKEEIEELEkeleslegskrklEEKIRELEERIEELKKEIEELEEKVKELK 286
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 634 A--ELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEECSKLEAQLKKqAEQLFNQMYNPAHNVEDDSRMnp 711
Cdd:PRK03918 287 ElkEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEE-LKKKLKELEKRLEELEERHEL-- 363
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 712 efADRIKQLDKEASYYRDEcgKAQAEVDRLLEILKEVENEKNDKDKKIAELEsltlRHMKDQNKKVANLKHNqqLEKKKN 791
Cdd:PRK03918 364 --YEEAKAKKEELERLKKR--LTGLTPEKLEKELEELEKAKEEIEEEISKIT----ARIGELKKEIKELKKA--IEELKK 433
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 792 AQLLEEVRRREdsmadnsqhLQIEELMNALEKTRQELDATKARLASTQQSLAEKEAHLANLRIERRKQLEEILEMKQEAL 871
Cdd:PRK03918 434 AKGKCPVCGRE---------LTEEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQ 504
|
410 420 430 440
....*....|....*....|....*....|....*....|....*
gi 1570463013 872 LAAISEKDANIALLELSASKKK--KTQEEVMALKREKDRLVHQLK 914
Cdd:PRK03918 505 LKELEEKLKKYNLEELEKKAEEyeKLKEKLIKLKGEIKSLKKELE 549
|
|
| COG5022 |
COG5022 |
Myosin heavy chain [General function prediction only]; |
219-852 |
1.57e-07 |
|
Myosin heavy chain [General function prediction only];
Pssm-ID: 227355 [Multi-domain] Cd Length: 1463 Bit Score: 55.85 E-value: 1.57e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 219 QHLQLTIQALQDELRTQRDLNHLLQQESGNRGAEHFTIELTEENFRRLQAEHDRQAKEL---FLLRKTLE-EMELRIETQ 294
Cdd:COG5022 768 LKRIKKIQVIQHGFRLRRLVDYELKWRLFIKLQPLLSLLGSRKEYRSYLACIIKLQKTIkreKKLRETEEvEFSLKAEVL 847
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 295 KQTLnARDESIKKLLEMLQSKGLPSKS---LEDDNERTRRMAEAESQVSHLEVILDQKEKENIHLREELH--RRSQLQPE 369
Cdd:COG5022 848 IQKF-GRSLKAKKRFSLLKKETIYLQSaqrVELAERQLQELKIDVKSISSLKLVNLELESEIIELKKSLSsdLIENLEFK 926
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 370 PAKTKALQTVIEMKDTKIASlERNIRDLEDEIQMLKANGVLN--TEDREEEIKQIEVYKSHSKFMKTKIDQLKQELSKKE 447
Cdd:COG5022 927 TELIARLKKLLNNIDLEEGP-SIEYVKLPELNKLHEVESKLKetSEEYEDLLKKSTILVREGNKANSELKNFKKELAELS 1005
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 448 SELLALQTK---LETLSNQNSDCKQHIEVLKESLTAKEQR-----------AAILQTEVDALRLRLEEKESFLNKKTKQL 513
Cdd:COG5022 1006 KQYGALQEStkqLKELPVEVAELQSASKIISSESTELSILkplqklkglllLENNQLQARYKALKLRRENSLLDDKQLYQ 1085
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 514 QDLTE--EKGTLAGEIRDMKDMLEVKERKINVL---QKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTA--LATL 586
Cdd:COG5022 1086 LESTEnlLKTINVKDLEVTNRNLVKPANVLQFIvaqMIKLNLLQEISKFLSQLVNTLEPVFQKLSVLQLELDGLfwEANL 1165
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 587 EEALSEKERIieRLKEQRERDDRERLEEIESFRKENKDLKEKVNAL----------QAELTEKESSLIDLKEHASSLASA 656
Cdd:COG5022 1166 EALPSPPPFA--ALSEKRLYQSALYDEKSKLSSSEVNDLKNELIALfskifsgwprGDKLKKLISEGWVPTEYSTSLKGF 1243
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 657 GLKRDSKLKSLEIAIEQKKEECSKLEAQLKKQAEQ--LFNQMYNPAHNVEDDSRMNPEFADRIK-----QLDKEASYYRD 729
Cdd:COG5022 1244 NNLNKKFDTPASMSNEKLLSLLNSIDNLLSSYKLEeeVLPATINSLLQYINVGLFNALRTKASSlrwksATEVNYNSEEL 1323
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 730 ECGKAQAEVDRLLE----------ILKEVENEKNDKDKKIAELESL---TLRHMKDQNkKVANLKHNqqLEKKKNAQLLE 796
Cdd:COG5022 1324 DDWCREFEISDVDEeleeliqavkVLQLLKDDLNKLDELLDACYSLnpaEIQNLKSRY-DPADKENN--LPKEILKKIEA 1400
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|....*.
gi 1570463013 797 EVRRREDSMADnsqhlqieELMNALEKTRQELDATKARLASTQQSLAEKEAHLANL 852
Cdd:COG5022 1401 LLIKQELQLSL--------EGKDETEVHLSEIFSEEKSLISLDRNSIYKEEVLSSL 1448
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
513-658 |
1.57e-07 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 55.63 E-value: 1.57e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 513 LQDLTEEKgtLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRdkdkqltNLKDRVKSLQTDssntdtaLATLEEALSE 592
Cdd:COG2433 382 LEELIEKE--LPEEEPEAEREKEHEERELTEEEEEIRRLEEQVE-------RLEAEVEELEAE-------LEEKDERIER 445
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1570463013 593 KERIIERLKEQRERDDRERlEEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGL 658
Cdd:COG2433 446 LERELSEARSEERREIRKD-REISRLDREIERLERELEEERERIEELKRKLERLKELWKLEHSGEL 510
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
331-865 |
1.62e-07 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 55.95 E-value: 1.62e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 331 RMAEAESQVSHLEVILDQKEKENIHLREELHRRSQLQPEPAKTKA-LQTVIEMKDTKIASLERNIRDLEDEIQML---KA 406
Cdd:pfam01576 20 RQQKAESELKELEKKHQQLCEEKNALQEQLQAETELCAEAEEMRArLAARKQELEEILHELESRLEEEEERSQQLqneKK 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 407 NGVLNTEDREEEIKQIEVYKSHSKFMKTKIDqlkQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAA 486
Cdd:pfam01576 100 KMQQHIQDLEEQLDEEEAARQKLQLEKVTTE---AKIKKLEEDILLLEDQNSKLSKERKLLEERISEFTSNLAEEEEKAK 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 487 ILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDmlevkerKINVLQKKIENLQEQLRDKDKQLTNLK 566
Cdd:pfam01576 177 SLSKLKNKHEAMISDLEERLKKEEKGRQELEKAKRKLEGESTDLQE-------QIAELQAQIAELRAQLAKKEEELQAAL 249
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 567 DRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRERL---EEIESFRKENKDLKEKVNALQAELTEKESSL 643
Cdd:pfam01576 250 ARLEEETAQKNNALKKIRELEAQISELQEDLESERAARNKAEKQRRdlgEELEALKTELEDTLDTTAAQQELRSKREQEV 329
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 644 IDLKE--------HASSLASAGLKRDSKLKSLEIAIEQKKEECSKLE---AQLKKQAEQLFNQMYNPAHNVEDDSRMNP- 711
Cdd:pfam01576 330 TELKKaleeetrsHEAQLQEMRQKHTQALEELTEQLEQAKRNKANLEkakQALESENAELQAELRTLQQAKQDSEHKRKk 409
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 712 ------EFADRIKQLDKEASYYRDECGKAQAEVDRLLEILKEVENEKNDKDKKIAELESL---TLRHMKDQNKKVANLKH 782
Cdd:pfam01576 410 legqlqELQARLSESERQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLESQlqdTQELLQEETRQKLNLST 489
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 783 N-QQLEKKKNAqLLEEVRRREDSMADNSQHLQIEELMNALEKTRQELDATKARLASTQQSLAEKEAHLANLRIERRKQLE 861
Cdd:pfam01576 490 RlRQLEDERNS-LQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEALEEGKKRLQRELEALTQQLEEKAAAY 568
|
....
gi 1570463013 862 EILE 865
Cdd:pfam01576 569 DKLE 572
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
261-897 |
1.86e-07 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 55.82 E-value: 1.86e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 261 ENFRRLQAEHDRQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKglpSKSLEDDNERTRRMAEAESQVS 340
Cdd:TIGR00606 189 ETLRQVRQTQGQKVQEHQMELKYLKQYKEKACEIRDQITSKEAQLESSREIVKSY---ENELDPLKNRLKEIEHNLSKIM 265
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 341 HLE---VILDQKEKENIHLREELHRRsQLQPEPAKTKALQTVIEMKDTKIASLERNIRDLEDEIqmlkanGVLNTEDREE 417
Cdd:TIGR00606 266 KLDneiKALKSRKKQMEKDNSELELK-MEKVFQGTDEQLNDLYHNHQRTVREKERELVDCQREL------EKLNKERRLL 338
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 418 EIKQIEVYKSHSKfMKTKIDQLKQELSKKESELLALQTKLET-----------------------LSNQNSDCKQHIEVL 474
Cdd:TIGR00606 339 NQEKTELLVEQGR-LQLQADRHQEHIRARDSLIQSLATRLELdgfergpfserqiknfhtlvierQEDEAKTAAQLCADL 417
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 475 KESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGeirDMKDMLEVKERkinvLQKKIENLqeQ 554
Cdd:TIGR00606 418 QSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKELQQLEG---SSDRILELDQE----LRKAEREL--S 488
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 555 LRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKeQRERDDRERLEEIESFRKENKDLKEKVNALQA 634
Cdd:TIGR00606 489 KAEKNSLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRT-QMEMLTKDKMDKDEQIRKIKSRHSDELTSLLG 567
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 635 ELTEK---ESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEECSKLEAQLKKQAEQLFNQMYNPAHNVEDDS---R 708
Cdd:TIGR00606 568 YFPNKkqlEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLFDVCGSQDEESDLERlkeE 647
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 709 MNPEFADR-------------IKQLDKEASYYRDECGKAQAEVDRLLEILKEVENEKNDKDKKIAELESLtLRHMKDQNK 775
Cdd:TIGR00606 648 IEKSSKQRamlagatavysqfITQLTDENQSCCPVCQRVFQTEAELQEFISDLQSKLRLAPDKLKSTESE-LKKKEKRRD 726
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 776 KVANLKHNQQLEKKKNAQLLEEVRRREDSMADnsqhlQIEELMNALEKTRQELDATKARLASTQQSLAEKEAhlanlrIE 855
Cdd:TIGR00606 727 EMLGLAPGRQSIIDLKEKEIPELRNKLQKVNR-----DIQRLKNDIEEQETLLGTIMPEEESAKVCLTDVTI------ME 795
|
650 660 670 680
....*....|....*....|....*....|....*....|..
gi 1570463013 856 RRKQLEEILEMKQEALLAAISEKDANIALLELSASKKKKTQE 897
Cdd:TIGR00606 796 RFQMELKDVERKIAQQAAKLQGSDLDRTVQQVNQEKQEKQHE 837
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
432-730 |
1.90e-07 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 54.91 E-value: 1.90e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 432 MKTKIDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTK 511
Cdd:COG4372 43 LQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQEEAEELQEELEELQK 122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 512 QLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKD-----RVKSLQTDSSNTDTALATL 586
Cdd:COG4372 123 ERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEaeaeqALDELLKEANRNAEKEEEL 202
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 587 EEALSEKERIIERLKEQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKRDSKLKS 666
Cdd:COG4372 203 AEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELELAILVEKDTEEEELEIAA 282
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1570463013 667 LEIAIEQKKEECSKLEAQLKKQAEQLFNQMYNPAHNVEDDSRMNPEFADRIKQLDKEASYYRDE 730
Cdd:COG4372 283 LELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLELALAILLAELADLLQLL 346
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
380-640 |
2.04e-07 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 55.69 E-value: 2.04e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 380 IEMKDTKIASLERNIRDLEDEIQmlKANGVLNT-EDREEEIKQIEVYKSHSKFMKT---KIDQLKQELSKKE---SELLA 452
Cdd:COG4913 612 LAALEAELAELEEELAEAEERLE--ALEAELDAlQERREALQRLAEYSWDEIDVASaerEIAELEAELERLDassDDLAA 689
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 453 LQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFlnKKTKQLQDLTEEKGTLAGEiRDMKD 532
Cdd:COG4913 690 LEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDL--ARLELRALLEERFAAALGD-AVERE 766
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 533 MLEVKERKINVLQKKIENLQEQLRDKdkqltnLKDRVKSLQTDSSNTDTALATLEEALSEKERII--------ERLKEQR 604
Cdd:COG4913 767 LRENLEERIDALRARLNRAEEELERA------MRAFNREWPAETADLDADLESLPEYLALLDRLEedglpeyeERFKELL 840
|
250 260 270
....*....|....*....|....*....|....*..
gi 1570463013 605 ERDDRERLEEIES-FRKENKDLKEKVNALQAELTEKE 640
Cdd:COG4913 841 NENSIEFVADLLSkLRRAIREIKERIDPLNDSLKRIP 877
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
500-931 |
4.16e-07 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 54.34 E-value: 4.16e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 500 EEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKI----ENLQEQLRDKDKQLTNLKDRVKSLQTD 575
Cdd:pfam05483 229 EEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKANQLEEKTklqdENLKELIEKKDHLTKELEDIKMSLQRS 308
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 576 SSNTDTalatLEEALSEKERIIERLKEQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLAS 655
Cdd:pfam05483 309 MSTQKA----LEEDLQIATKTICQLTEEKEAQMEELNKAKAAHSFVVTEFEATTCSLEELLRTEQQRLEKNEDQLKIITM 384
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 656 AGLKRDSKLKSLEIAIEQKKEECSKLEAQLKKQaEQLFNQMYNPAHNVEDDSRMNPEFADRIKQLDKEASYYRDECGKAQ 735
Cdd:pfam05483 385 ELQKKSSELEEMTKFKNNKEVELEELKKILAED-EKLLDEKKQFEKIAEELKGKEQELIFLLQAREKEIHDLEIQLTAIK 463
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 736 AEVDRLLEILKEVENEKNDKDKKIAELESlTLRHMKDQNKKVANLKHNQQLEKKKNAQLLEEVRRREDSMADNSQHLQIE 815
Cdd:pfam05483 464 TSEEHYLKEVEDLKTELEKEKLKNIELTA-HCDKLLLENKELTQEASDMTLELKKHQEDIINCKKQEERMLKQIENLEEK 542
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 816 E--LMNALEKTRQEL----DATKARLASTqqslaEKEAHLANLRIERRKQLEEILEMKQEALLAAISEKDANIALL--EL 887
Cdd:pfam05483 543 EmnLRDELESVREEFiqkgDEVKCKLDKS-----EENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELhqEN 617
|
410 420 430 440
....*....|....*....|....*....|....*....|....*.
gi 1570463013 888 SASKKKKTQE--EVMALKREKDRLVHQLkQQTQNRMKLMADNYDED 931
Cdd:pfam05483 618 KALKKKGSAEnkQLNAYEIKVNKLELEL-ASAKQKFEEIIDNYQKE 662
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
285-915 |
4.21e-07 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 54.41 E-value: 4.21e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 285 EEMELRIETQKQTLnardesiKKLLEMLQSKglpsksLEDDNERTRRMAEAESQVShlEVILDQKEkeniHLREELHRRS 364
Cdd:pfam01576 60 EEMRARLAARKQEL-------EEILHELESR------LEEEEERSQQLQNEKKKMQ--QHIQDLEE----QLDEEEAARQ 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 365 QLQPEP----AKTKALQTVIEMKDTKIASLERNIRDLEDEIQMLKAngvlNTEDREEEIKQIEVYKSHSKFMKTKI-DQL 439
Cdd:pfam01576 121 KLQLEKvtteAKIKKLEEDILLLEDQNSKLSKERKLLEERISEFTS----NLAEEEEKAKSLSKLKNKHEAMISDLeERL 196
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 440 KQElSKKESELLALQTKLE----TLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVD---------------------A 494
Cdd:pfam01576 197 KKE-EKGRQELEKAKRKLEgestDLQEQIAELQAQIAELRAQLAKKEEELQAALARLEeetaqknnalkkireleaqisE 275
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 495 LRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEV-------KERKINVLQKKIEnlqEQLRDKDKQLTNLKD 567
Cdd:pfam01576 276 LQEDLESERAARNKAEKQRRDLGEELEALKTELEDTLDTTAAqqelrskREQEVTELKKALE---EETRSHEAQLQEMRQ 352
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 568 RvkslqtdssnTDTALATLEEALSEKERI---IERLKEQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESSLI 644
Cdd:pfam01576 353 K----------HTQALEELTEQLEQAKRNkanLEKAKQALESENAELQAELRTLQQAKQDSEHKRKKLEGQLQELQARLS 422
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 645 DLKEHASSLASAGLKRDSKLKSLEIAIEQKKEECSKLEaqlkKQAEQLFNQMYNPAHNVEDDSRMNPEFADRIKQLDKEA 724
Cdd:pfam01576 423 ESERQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLS----KDVSSLESQLQDTQELLQEETRQKLNLSTRLRQLEDER 498
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 725 SYYR---DECGKAQAEVDRLLEILkeveNEKNDKDKKIAELESLTLRHMKDQNKKVANLKH--NQQLEKKKNA-QLLEEV 798
Cdd:pfam01576 499 NSLQeqlEEEEEAKRNVERQLSTL----QAQLSDMKKKLEEDAGTLEALEEGKKRLQRELEalTQQLEEKAAAyDKLEKT 574
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 799 RRREDSmadnsqhlQIEELMNALEKTRQELDATKARLASTQQSLAEKEAHLANLRIERRKQLEEILEMKQEALLAAISEK 878
Cdd:pfam01576 575 KNRLQQ--------ELDDLLVDLDHQRQLVSNLEKKQKKFDQMLAEEKAISARYAEERDRAEAEAREKETRALSLARALE 646
|
650 660 670
....*....|....*....|....*....|....*....
gi 1570463013 879 DANIALLELSASKK--KKTQEEVMALKREKDRLVHQLKQ 915
Cdd:pfam01576 647 EALEAKEELERTNKqlRAEMEDLVSSKDDVGKNVHELER 685
|
|
| 46 |
PHA02562 |
endonuclease subunit; Provisional |
565-801 |
4.32e-07 |
|
endonuclease subunit; Provisional
Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 54.25 E-value: 4.32e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 565 LKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQrERDDRERLEE-IESFRKENKDLKEKVNALQAELTEKESSL 643
Cdd:PHA02562 172 NKDKIRELNQQIQTLDMKIDHIQQQIKTYNKNIEEQRKK-NGENIARKQNkYDELVEEAKTIKAEIEELTDELLNLVMDI 250
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 644 IDLKEHASSLASAGLKRDSKLKSL--EIAIEQKKEECSKLEAQLKKQAE---QLFNQMYNPAHNVEDdsrmnpeFADRIK 718
Cdd:PHA02562 251 EDPSAALNKLNTAAAKIKSKIEQFqkVIKMYEKGGVCPTCTQQISEGPDritKIKDKLKELQHSLEK-------LDTAID 323
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 719 QLDKEASYYRDecgkaqaEVDRLLEILKEVENEK------NDKDKKI-AELESLTLRHmKDQNKKVANLKHNQQLEKKKN 791
Cdd:PHA02562 324 ELEEIMDEFNE-------QSKKLLELKNKISTNKqslitlVDKAKKVkAAIEELQAEF-VDNAEELAKLQDELDKIVKTK 395
|
250
....*....|
gi 1570463013 792 AQLLEEVRRR 801
Cdd:PHA02562 396 SELVKEKYHR 405
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
139-930 |
6.44e-07 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 53.90 E-value: 6.44e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 139 LRQVRDSTMLDLQAQLKELQRENDLLRKELDIKDsKLGSSMNsiktfwspELKKERVLRKEEAARMSVLKEQMRvsheEN 218
Cdd:TIGR00606 191 LRQVRQTQGQKVQEHQMELKYLKQYKEKACEIRD-QITSKEA--------QLESSREIVKSYENELDPLKNRLK----EI 257
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 219 QHLQLTIQALQDELRTQRDLNhlLQQESGNRGAEHFTIEL---TEENFRRLQAEHDRQAKElfllrKTLEEMELRIETQK 295
Cdd:TIGR00606 258 EHNLSKIMKLDNEIKALKSRK--KQMEKDNSELELKMEKVfqgTDEQLNDLYHNHQRTVRE-----KERELVDCQRELEK 330
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 296 QTLNARDESIKKLlEMLQSKGLPSKSLEDDNERTR-RMAEAESQVSHLEV-ILDQKEKENIHLREELHRRSQLQPEPAKT 373
Cdd:TIGR00606 331 LNKERRLLNQEKT-ELLVEQGRLQLQADRHQEHIRaRDSLIQSLATRLELdGFERGPFSERQIKNFHTLVIERQEDEAKT 409
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 374 KAlQTVIEMKDtKIASLERNIRDLEDEIQMLKANGVLNTEDREEEIKQIEVYKSHSKFMKTKID---QLKQELSKKESEL 450
Cdd:TIGR00606 410 AA-QLCADLQS-KERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKELQQLEGSSDrilELDQELRKAEREL 487
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 451 LALQtkletlSNQNSDCKqhievLKESLTAKEQRAAILQTevdalRLRLEEKESFLNKKT---KQLQDLTEEKGTLAGEI 527
Cdd:TIGR00606 488 SKAE------KNSLTETL-----KKEVKSLQNEKADLDRK-----LRKLDQEMEQLNHHTttrTQMEMLTKDKMDKDEQI 551
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 528 RDMKDMLEVKERKI-------NVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSE-KERIIER 599
Cdd:TIGR00606 552 RKIKSRHSDELTSLlgyfpnkKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSyEDKLFDV 631
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 600 LKEQRERDDRERL-EEIESFRKENKDLKEKVNALQA---ELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKK 675
Cdd:TIGR00606 632 CGSQDEESDLERLkEEIEKSSKQRAMLAGATAVYSQfitQLTDENQSCCPVCQRVFQTEAELQEFISDLQSKLRLAPDKL 711
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 676 EECSKLEAQLKKQAEQLFNQMYNPAHNVEDDSRMNPEFADRIKQLDKEASYYRDECGKAQAEVDRLLEILKEVENEKNDk 755
Cdd:TIGR00606 712 KSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAKVCLTD- 790
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 756 dkkIAELESLTLRhMKDQNKKVAnlkhnQQLEKKKNAQLLEEVRRREDSMADNSQHL-QIEELMNALEKTRQELDATKAR 834
Cdd:TIGR00606 791 ---VTIMERFQME-LKDVERKIA-----QQAAKLQGSDLDRTVQQVNQEKQEKQHELdTVVSKIELNRKLIQDQQEQIQH 861
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 835 LASTQQSLAEKEAHLANlRIERRKQLEEILEMKQEALLAAISE-KDANIALLELSASKKKKTQEEVMALKREkdrlvHQL 913
Cdd:TIGR00606 862 LKSKTNELKSEKLQIGT-NLQRRQQFEEQLVELSTEVQSLIREiKDAKEQDSPLETFLEKDQQEKEELISSK-----ETS 935
|
810
....*....|....*..
gi 1570463013 914 KQQTQNRMKLMADNYDE 930
Cdd:TIGR00606 936 NKKAQDKVNDIKEKVKN 952
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
281-648 |
9.37e-07 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 53.14 E-value: 9.37e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 281 RKTLEEMELRIETQKQTLNARDESIKKLLEMLQS-KG---LPSKSLEDD------NERTRRMAEAESQVSHLEVILDQKE 350
Cdd:PRK03918 400 KEEIEEEISKITARIGELKKEIKELKKAIEELKKaKGkcpVCGRELTEEhrkellEEYTAELKRIEKELKEIEEKERKLR 479
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 351 KENIHLREELHRRSQLQPEPAKTKALQTV-----------IEMKDTKIASLERNIRDLEDEIQMLKangvlntedreEEI 419
Cdd:PRK03918 480 KELRELEKVLKKESELIKLKELAEQLKELeeklkkynleeLEKKAEEYEKLKEKLIKLKGEIKSLK-----------KEL 548
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 420 KQIEVYKSHSKFMKTKIDQLKQELSKKESELLALQTKL-----ETLSNQNSDCKQHIEVL--KESLTAKEQRAAILQTEV 492
Cdd:PRK03918 549 EKLEELKKKLAELEKKLDELEEELAELLKELEELGFESveeleERLKELEPFYNEYLELKdaEKELEREEKELKKLEEEL 628
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 493 DALRLRLEEKESFLNKKTKQLQDLteEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSL 572
Cdd:PRK03918 629 DKAFEELAETEKRLEELRKELEEL--EKKYSEEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEER 706
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1570463013 573 qtdsSNTDTALATLEEALSEKERIIERLKEQRERDDRERLEEIESFRKEnkdlkekvnaLQAELTEKESSLIDLKE 648
Cdd:PRK03918 707 ----EKAKKELEKLEKALERVEELREKVKKYKALLKERALSKVGEIASE----------IFEELTEGKYSGVRVKA 768
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
650-898 |
9.80e-07 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 52.46 E-value: 9.80e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 650 ASSLASAGLKRDSKLKSLEIAIEQKKEECSKLEAQLKKQAEQLFNQmynpahnveddsrmnpefADRIKQLDKEASYYRD 729
Cdd:COG4942 15 AAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAAL------------------ERRIAALARRIRALEQ 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 730 ECGKAQAEVDRLLEILKEVENEKNDKDKKIAELesLTLRHMKDQNKKVANLKHNQQ-LEKKKNAQLLEEVRRredsmADN 808
Cdd:COG4942 77 ELAALEAELAELEKEIAELRAELEAQKEELAEL--LRALYRLGRQPPLALLLSPEDfLDAVRRLQYLKYLAP-----ARR 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 809 SQHLQIEELMNALEKTRQELDATKARLASTQQSLAEKEAHLANLRIERRKQLEEiLEMKQEALLAAISEKDANIALLELS 888
Cdd:COG4942 150 EQAEELRADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLAR-LEKELAELAAELAELQQEAEELEAL 228
|
250
....*....|
gi 1570463013 889 ASKKKKTQEE 898
Cdd:COG4942 229 IARLEAEAAA 238
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
268-684 |
1.34e-06 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 52.46 E-value: 1.34e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 268 AEHDRQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLPSK------SLEDDNERTRRMAEAESQVSH 341
Cdd:COG4717 81 KEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQElealeaELAELPERLEELEERLEELRE 160
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 342 LEVILDQKEKENIHLREELhRRSQLQPEPAKTKALQTVIEmkdtKIASLERNIRDLEDEIQMLKANGvlntEDREEEIKQ 421
Cdd:COG4717 161 LEEELEELEAELAELQEEL-EELLEQLSLATEEELQDLAE----ELEELQQRLAELEEELEEAQEEL----EELEEELEQ 231
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 422 IEVYKSHSKfMKTKIDQLKQeLSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEE 501
Cdd:COG4717 232 LENELEAAA-LEERLKEARL-LLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQA 309
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 502 KESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRdkdkQLTNLKDRVKSLQTDSSNTDT 581
Cdd:COG4717 310 LPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQ----LEELEQEIAALLAEAGVEDEE 385
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 582 ALATLEEALSEKERIIERLKEQRERDDRERLEEIESFRKENKD-LKEKVNALQAELTEKESSLIDLKEHASSLAS--AGL 658
Cdd:COG4717 386 ELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEeLEEELEELEEELEELEEELEELREELAELEAelEQL 465
|
410 420
....*....|....*....|....*.
gi 1570463013 659 KRDSKLKSLEIAIEQKKEECSKLEAQ 684
Cdd:COG4717 466 EEDGELAELLQELEELKAELRELAEE 491
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
713-907 |
1.61e-06 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 51.75 E-value: 1.61e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 713 FAD-RIKQLDKEASYYRDECGKAQAEVDRLLEILKEVENEKNDKDKKIAELEsltlRHMKDQNKKVANLkhNQQLEKKK- 790
Cdd:COG3883 13 FADpQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQ----AEIDKLQAEIAEA--EAEIEERRe 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 791 -----------------------NAQLLEEVRRREDSM-----ADNSQHLQIEELMNALEKTRQELDATKARLASTQQSL 842
Cdd:COG3883 87 elgeraralyrsggsvsyldvllGSESFSDFLDRLSALskiadADADLLEELKADKAELEAKKAELEAKLAELEALKAEL 166
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1570463013 843 AEKEAHLANLRIERRKQLEEiLEMKQEALLAAISEKDANIALLELSASKKKKTQEEVMALKREKD 907
Cdd:COG3883 167 EAAKAELEAQQAEQEALLAQ-LSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAA 230
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
706-877 |
1.65e-06 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 50.69 E-value: 1.65e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 706 DSRMNpEFADRIKQLDKEASYYRDECGKAQAEVDRLLEILKEVENEKNDKDKKIAELESLtLRHMKDQNKKVANLKHNQQ 785
Cdd:COG1579 16 DSELD-RLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEAR-IKKYEEQLGNVRNNKEYEA 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 786 LEKKknaqlLEEVRRREDSMADnsqhlQIEELMNALEKTRQELDATKARLASTQQSLAEKEAHLANLRIERRKQLEEILE 865
Cdd:COG1579 94 LQKE-----IESLKRRISDLED-----EILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEA 163
|
170
....*....|..
gi 1570463013 866 mKQEALLAAISE 877
Cdd:COG1579 164 -EREELAAKIPP 174
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
384-558 |
1.89e-06 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 50.31 E-value: 1.89e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 384 DTKIASLERNIRDLEDEIQMLKAngvlNTEDREEEIKQIevykshskfmKTKIDQLKQELSKKESELLALQTKLETLSNQ 463
Cdd:COG1579 16 DSELDRLEHRLKELPAELAELED----ELAALEARLEAA----------KTELEDLEKEIKRLELEIEEVEARIKKYEEQ 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 464 nsdckqhievLKESLTAKEQRAaiLQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINV 543
Cdd:COG1579 82 ----------LGNVRNNKEYEA--LQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDE 149
|
170
....*....|....*
gi 1570463013 544 LQKKIENLQEQLRDK 558
Cdd:COG1579 150 ELAELEAELEELEAE 164
|
|
| PTZ00108 |
PTZ00108 |
DNA topoisomerase 2-like protein; Provisional |
383-690 |
2.94e-06 |
|
DNA topoisomerase 2-like protein; Provisional
Pssm-ID: 240271 [Multi-domain] Cd Length: 1388 Bit Score: 51.97 E-value: 2.94e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 383 KDTKIASLERNIRDLEDEIQMLKA--NGVLNT-----EDREEEIKQIEvYKSHSKFMKTKIDQLKQELSKKESELLALQT 455
Cdd:PTZ00108 997 KEYLLGKLERELARLSNKVRFIKHviNGELVItnakkKDLVKELKKLG-YVRFKDIIKKKSEKITAEEEEGAEEDDEADD 1075
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 456 KLETLSNQNSDC-------------KQHIEVLKESLTAKEQRAAILQ---------TEVDALRLRLEEKESFLNKKTKQL 513
Cdd:PTZ00108 1076 EDDEEELGAAVSydyllsmpiwsltKEKVEKLNAELEKKEKELEKLKnttpkdmwlEDLDKFEEALEEQEEVEEKEIAKE 1155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 514 QDLTEEKGTLAGEIRDMKDMLEVKERKIN----------VLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTAL 583
Cdd:PTZ00108 1156 QRLKSKTKGKASKLRKPKLKKKEKKKKKSsadkskkasvVGNSKRVDSDEKRKLDDKPDNKKSNSSGSDQEDDEEQKTKP 1235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 584 ATLEEALSEKERIIERLKEQRERDDRERLEEIESFRkenKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKRDSK 663
Cdd:PTZ00108 1236 KKSSVKRLKSKKNNSSKSSEDNDEFSSDDLSKEGKP---KNAPKRVSAVQYSPPPPSKRPDGESNGGSKPSSPTKKKVKK 1312
|
330 340
....*....|....*....|....*...
gi 1570463013 664 -LKSLEIAIEQKKEECSKLEAQLKKQAE 690
Cdd:PTZ00108 1313 rLEGSLAALKKKKKSEKKTARKKKSKTR 1340
|
|
| PRK01156 |
PRK01156 |
chromosome segregation protein; Provisional |
149-632 |
3.09e-06 |
|
chromosome segregation protein; Provisional
Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 51.44 E-value: 3.09e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 149 DLQAQLKELQRENDLLRKELDIKDSK---LGSSMNSIKTFWSPELKKERVLRKEEAARMSVLKEQMRVSHEENQHLQLTI 225
Cdd:PRK01156 208 DDEKSHSITLKEIERLSIEYNNAMDDynnLKSALNELSSLEDMKNRYESEIKTAESDLSMELEKNNYYKELEERHMKIIN 287
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 226 QA-------LQDELRTQRDLNHLLQQESGNRGaehfTIELTEENFRR---LQAEHD------RQAKELFLLRKTLEEMEL 289
Cdd:PRK01156 288 DPvyknrnyINDYFKYKNDIENKKQILSNIDA----EINKYHAIIKKlsvLQKDYNdyikkkSRYDDLNNQILELEGYEM 363
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 290 R-------IETQKQTLNARDESIKKLLEMLQSKGL-----PSKSLEDDNERTRRMAEAESQVSHLEVILDQKEKENIHLR 357
Cdd:PRK01156 364 DynsylksIESLKKKIEEYSKNIERMSAFISEILKiqeidPDAIKKELNEINVKLQDISSKVSSLNQRIRALRENLDELS 443
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 358 EELHRRSQLQPEPA-----KTKALQTVIEMKDTKIASLERNIRDLEDEIQMLKaNGVLNTEDREEEI--KQIEVYKSHSK 430
Cdd:PRK01156 444 RNMEMLNGQSVCPVcgttlGEEKSNHIINHYNEKKSRLEEKIREIEIEVKDID-EKIVDLKKRKEYLesEEINKSINEYN 522
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 431 FMKTKIDQLKqELSKKESELLALQTKLETLSNQNSDCkqHIEVLK----ESLTAKEQRAAIlqtEVDALRLRLEEKesfl 506
Cdd:PRK01156 523 KIESARADLE-DIKIKINELKDKHDKYEEIKNRYKSL--KLEDLDskrtSWLNALAVISLI---DIETNRSRSNEI---- 592
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 507 nkkTKQLQDLTEEKGTLAGEIRDMK---------------------DMLEVKERKINVLQKKIENLQEQLRDKD---KQL 562
Cdd:PRK01156 593 ---KKQLNDLESRLQEIEIGFPDDKsyidksireieneannlnnkyNEIQENKILIEKLRGKIDNYKKQIAEIDsiiPDL 669
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1570463013 563 TNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLK------EQRERDDRERLEEIESFRKENKDLKEKVNAL 632
Cdd:PRK01156 670 KEITSRINDIEDNLKKSRKALDDAKANRARLESTIEILRtrinelSDRINDINETLESMKKIKKAIGDLKRLREAF 745
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
144-906 |
3.22e-06 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 51.71 E-value: 3.22e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 144 DSTMLDLQAQLKELQRENDLLRKELDIKDSKLGSSMNSIK---TFWSPELKKERVLR-----------KEEAARMSVLKe 209
Cdd:pfam01576 214 EGESTDLQEQIAELQAQIAELRAQLAKKEEELQAALARLEeetAQKNNALKKIRELEaqiselqedleSERAARNKAEK- 292
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 210 QMRVSHEENQHLQ------LTIQALQDELRTQRDLNHLLQQESGNRGAEHFTIELTEenfrrLQAEHDRQAKELFLLRKT 283
Cdd:pfam01576 293 QRRDLGEELEALKteledtLDTTAAQQELRSKREQEVTELKKALEEETRSHEAQLQE-----MRQKHTQALEELTEQLEQ 367
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 284 LEEMELRIETQKQTLNARDESIKKLLEMLQSKglpskslEDDNERTRRmaEAESQVSHLEVILDQKEKENIHLREELHRr 363
Cdd:pfam01576 368 AKRNKANLEKAKQALESENAELQAELRTLQQA-------KQDSEHKRK--KLEGQLQELQARLSESERQRAELAEKLSK- 437
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 364 sqLQPEPAKTKALQTVIEMKDTK----IASLERNIRDLEDEIQmlkangvlntedreEEIKQIEVYKSHSKFMKTKIDQL 439
Cdd:pfam01576 438 --LQSELESVSSLLNEAEGKNIKlskdVSSLESQLQDTQELLQ--------------EETRQKLNLSTRLRQLEDERNSL 501
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 440 KQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQlqdltee 519
Cdd:pfam01576 502 QEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEALEEGKKRLQRELEALTQQLEEKAAAYDKLEKT------- 574
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 520 KGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIER 599
Cdd:pfam01576 575 KNRLQQELDDLLVDLDHQRQLVSNLEKKQKKFDQMLAEEKAISARYAEERDRAEAEAREKETRALSLARALEEALEAKEE 654
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 600 LKEQReRDDRERLEEIESFR----KENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAI---- 671
Cdd:pfam01576 655 LERTN-KQLRAEMEDLVSSKddvgKNVHELERSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNMQALKAQFerdl 733
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 672 ----EQKKEECSKLEAQLKKQAEQLFNQMYNPAHNVEDDSRMNPEFADRIKQLDkEASYYRDECGKA-----------QA 736
Cdd:pfam01576 734 qardEQGEEKRRQLVKQVRELEAELEDERKQRAQAVAAKKKLELDLKELEAQID-AANKGREEAVKQlkklqaqmkdlQR 812
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 737 EVDRLLEILKEVENEKNDKDKKIAELESLTLRHMKD-----QNKKVANLKHNQQLEK-----KKNAQLLEEVRRREDSMA 806
Cdd:pfam01576 813 ELEEARASRDEILAQSKESEKKLKNLEAELLQLQEDlaaseRARRQAQQERDELADEiasgaSGKSALQDEKRRLEARIA 892
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 807 DNSQHLQIE----ELMN-ALEKTRQELDATKARLASTQQSLAEKEahlaNLRIERRKQLEEILEMKQEALLAAISEKDAN 881
Cdd:pfam01576 893 QLEEELEEEqsntELLNdRLRKSTLQVEQLTTELAAERSTSQKSE----SARQQLERQNKELKAKLQEMEGTVKSKFKSS 968
|
810 820
....*....|....*....|....*
gi 1570463013 882 IALLElsaSKKKKTQEEVMALKREK 906
Cdd:pfam01576 969 IAALE---AKIAQLEEQLEQESRER 990
|
|
| PLN02939 |
PLN02939 |
transferase, transferring glycosyl groups |
493-759 |
5.00e-06 |
|
transferase, transferring glycosyl groups
Pssm-ID: 215507 [Multi-domain] Cd Length: 977 Bit Score: 51.06 E-value: 5.00e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 493 DALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKK----IENLQEQLRDKDKqltnLKDR 568
Cdd:PLN02939 96 DHNRASMQRDEAIAAIDNEQQTNSKDGEQLSDFQLEDLVGMIQNAEKNILLLNQArlqaLEDLEKILTEKEA----LQGK 171
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 569 VKSLQTDSSNTDTALAtleeaLSEKERI-IERLKEQRERDDRERL--------------EEIESFRKENKDLKEKVNALQ 633
Cdd:PLN02939 172 INILEMRLSETDARIK-----LAAQEKIhVEILEEQLEKLRNELLirgateglcvhslsKELDVLKEENMLLKDDIQFLK 246
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 634 AELT------------EKESSLID--LKEHASSLASAglKRD-SKLKSLEI-AIEQKKEECSKLEAQLKKQAEQlfnqmy 697
Cdd:PLN02939 247 AELIevaeteervfklEKERSLLDasLRELESKFIVA--QEDvSKLSPLQYdCWWEKVENLQDLLDRATNQVEK------ 318
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1570463013 698 npAHNVEDDSRMNPEFADRIKQLDKEASYYRDECGKaqaeVDRLLEILKEVENEKNDKDKKI 759
Cdd:PLN02939 319 --AALVLDQNQDLRDKVDKLEASLKEANVSKFSSYK----VELLQQKLKLLEERLQASDHEI 374
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
482-695 |
6.15e-06 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 50.68 E-value: 6.15e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 482 EQRAAILQTEVDALRlRLEEKESFLNKKTKQLQDLTE------EKGTLAGEIRDMKDMLEV--KERKINVLQKKIENLQE 553
Cdd:COG4913 224 FEAADALVEHFDDLE-RAHEALEDAREQIELLEPIRElaeryaAARERLAELEYLRAALRLwfAQRRLELLEAELEELRA 302
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 554 QLRDkdkqltnlkdrvkslqtdssnTDTALATLEEALSEKERIIERLKEQRERDDRERLEEIEsfrKENKDLKEKVNALQ 633
Cdd:COG4913 303 ELAR---------------------LEAELERLEARLDALREELDELEAQIRGNGGDRLEQLE---REIERLERELEERE 358
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1570463013 634 AELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEECSKLEAQLKKQAEQLFNQ 695
Cdd:COG4913 359 RRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRE 420
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
371-599 |
6.63e-06 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 50.40 E-value: 6.63e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 371 AKTKALQTVIEMKDTKIASLERNIRDLEDEIQMLKA-NGVLNTEDREEEIKQievykshskfmktKIDQLKQELSKKESE 449
Cdd:COG3206 168 LRREEARKALEFLEEQLPELRKELEEAEAALEEFRQkNGLVDLSEEAKLLLQ-------------QLSELESQLAEARAE 234
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 450 LLALQTKLETLSNQNSDCKQHIEVLKES--LTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEkgtLAGEI 527
Cdd:COG3206 235 LAEAEARLAALRAQLGSGPDALPELLQSpvIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQ---LQQEA 311
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 528 RDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNT----DTALATLEEALSEKE------RII 597
Cdd:COG3206 312 QRILASLEAELEALQAREASLQAQLAQLEARLAELPELEAELRRLEREVEVArelyESLLQRLEEARLAEAltvgnvRVI 391
|
..
gi 1570463013 598 ER 599
Cdd:COG3206 392 DP 393
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
435-918 |
9.08e-06 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 50.22 E-value: 9.08e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 435 KIDQLKQELSKKESELLALQTkletlsnqnsdckqhievLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQ 514
Cdd:pfam12128 242 EFTKLQQEFNTLESAELRLSH------------------LHFGYKSDETLIASRQEERQETSAELNQLLRTLDDQWKEKR 303
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 515 D-LTEEKGTLAGEIRDMKDMLEV-KERKINVLQKKIENLQEQLrdkdkqltnlkDRVKSLQTDSSNTDTALATLEEALSE 592
Cdd:pfam12128 304 DeLNGELSAADAAVAKDRSELEAlEDQHGAFLDADIETAAADQ-----------EQLPSWQSELENLEERLKALTGKHQD 372
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 593 KERIIERLKEQRERDDRERLEEIESFRKENKDLKEK--------VNALQAELTEK-ESSLIDLKEHASSLASAGLKRDSK 663
Cdd:pfam12128 373 VTAKYNRRRSKIKEQNNRDIAGIKDKLAKIREARDRqlavaeddLQALESELREQlEAGKLEFNEEEYRLKSRLGELKLR 452
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 664 LKSLEIA------IEQKKEECSKL-EAQLKKQAEQLFNQMYNPAHNVEDDsrmnpEFADRIKQLDKEASYYRDECGKAQA 736
Cdd:pfam12128 453 LNQATATpelllqLENFDERIERArEEQEAANAEVERLQSELRQARKRRD-----QASEALRQASRRLEERQSALDELEL 527
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 737 EVD----RLLEILKeveNEKNDKDKKIAELESLTLRHMKD--------QNKKVANLK----HNQQLEKKKNAQLLEEVRR 800
Cdd:pfam12128 528 QLFpqagTLLHFLR---KEAPDWEQSIGKVISPELLHRTDldpevwdgSVGGELNLYgvklDLKRIDVPEWAASEEELRE 604
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 801 RED--SMADNSQHLQIEELMNALEKTRQELDATKARLASTQQSLAEKEAHLANLRIERRkqleeilemkqeallaaiSEK 878
Cdd:pfam12128 605 RLDkaEEALQSAREKQAAAEEQLVQANGELEKASREETFARTALKNARLDLRRLFDEKQ------------------SEK 666
|
490 500 510 520
....*....|....*....|....*....|....*....|
gi 1570463013 879 DaniALLELSASKKKKTQEEVMALKREKDRLVHQLKQQTQ 918
Cdd:pfam12128 667 D---KKNKALAERKDSANERLNSLEAQLKQLDKKHQAWLE 703
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
430-633 |
1.12e-05 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 49.39 E-value: 1.12e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 430 KFMKTKIDQLKQELSK--KESELLALQTKLETLSNQnsdcKQHIEVLKESLtakEQRAAILQTEVDALRLRLEEKESFLN 507
Cdd:PRK12704 27 KIAEAKIKEAEEEAKRilEEAKKEAEAIKKEALLEA----KEEIHKLRNEF---EKELRERRNELQKLEKRLLQKEENLD 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 508 KKTKQLQDLTEEkgtlageIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLkdrvkslqtdssntdtalaTLE 587
Cdd:PRK12704 100 RKLELLEKREEE-------LEKKEKELEQKQQELEKKEEELEELIEEQLQELERISGL-------------------TAE 153
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 1570463013 588 EAlseKERIIERLKEQRERDDRERLEEIESFRKENKDLKEK---VNALQ 633
Cdd:PRK12704 154 EA---KEILLEKVEEEARHEAAVLIKEIEEEAKEEADKKAKeilAQAIQ 199
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
244-621 |
1.23e-05 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 49.58 E-value: 1.23e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 244 QESGNRGAEHFTIELTEENFRRLQAEHDRQAKELFLLRKTLEEMELRIETQKQTLNardesIKKLLEMLQSKGLPSKSLE 323
Cdd:pfam02463 644 KESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQL-----EIKKKEQREKEELKKLKLE 718
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 324 DDNERTRRMAEAESQVSHLEVILDQKEKENIHLREEL-HRRSQLQPEPAKTKALQTVIEMKDTKIASLERNIRDLEDEIQ 402
Cdd:pfam02463 719 AEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSrLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKA 798
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 403 MLKANGVLNTEDREEEIKQIEVYKSHSKFMKTKIDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKE 482
Cdd:pfam02463 799 QEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEE 878
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 483 QRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQL 562
Cdd:pfam02463 879 LEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEE 958
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1570463013 563 TNLKDRVKSLQTDSSNTD----TALATLEEALSEKERIIERLKEQRERDDRERLEEIESFRKE 621
Cdd:pfam02463 959 EERNKRLLLAKEELGKVNlmaiEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQRLKE 1021
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
591-899 |
1.28e-05 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 49.65 E-value: 1.28e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 591 SEKERIIE------RLKEQRER-------------DDRERLEEIES--FRKENKDLKEKVNALQAELTEKESsliDLKEH 649
Cdd:PRK02224 149 SDRQDMIDdllqlgKLEEYRERasdarlgvervlsDQRGSLDQLKAqiEEKEEKDLHERLNGLESELAELDE---EIERY 225
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 650 ASSLASAGLKRDSKLKSLEiAIEQKKEECSKLEAQLKKQAEqlfnqmynpahNVEDDSRMNPEFADRIK-------QLDK 722
Cdd:PRK02224 226 EEQREQARETRDEADEVLE-EHEERREELETLEAEIEDLRE-----------TIAETEREREELAEEVRdlrerleELEE 293
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 723 EASYYRDECGKAQAEVDRLLEILKEVENEKNDKDKKIAELESLTLRHMKDQN---KKVANLKHNQQLEKKKNAQLLEEVR 799
Cdd:PRK02224 294 ERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAEslrEDADDLEERAEELREEAAELESELE 373
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 800 RREDSMADNSQHL-----QIEELMNALEKTRQELDATKARLAS-------TQQSLAEKEAHLANLRiERRKQLEEILE-- 865
Cdd:PRK02224 374 EAREAVEDRREEIeeleeEIEELRERFGDAPVDLGNAEDFLEElreerdeLREREAELEATLRTAR-ERVEEAEALLEag 452
|
330 340 350 360
....*....|....*....|....*....|....*....|..
gi 1570463013 866 --------MKQEALLAAISEKDANIALLELSASKKKKTQEEV 899
Cdd:PRK02224 453 kcpecgqpVEGSPHVETIEEDRERVEELEAELEDLEEEVEEV 494
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
259-928 |
1.39e-05 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 49.40 E-value: 1.39e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 259 TEENFRRLQAEHDRqakelflLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLpsksleDDNERTRRMAEAESQ 338
Cdd:pfam01576 206 LEKAKRKLEGESTD-------LQEQIAELQAQIAELRAQLAKKEEELQAALARLEEETA------QKNNALKKIRELEAQ 272
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 339 VSHLEVILDQK-------EKENIHLREELHR-RSQLQPEPAKTKALQTVIEMKDTKIASLERNI----RDLEDEIQMLKA 406
Cdd:pfam01576 273 ISELQEDLESEraarnkaEKQRRDLGEELEAlKTELEDTLDTTAAQQELRSKREQEVTELKKALeeetRSHEAQLQEMRQ 352
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 407 NGVLNTEDREEEIKQievykshSKFMKTKIDQLKQELskkESELLALQTKLETLSNQNSDC---KQHIEVLKESLTAK-- 481
Cdd:pfam01576 353 KHTQALEELTEQLEQ-------AKRNKANLEKAKQAL---ESENAELQAELRTLQQAKQDSehkRKKLEGQLQELQARls 422
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 482 ---------EQRAAILQTEVDALRLRLEEKESFLNKKTK-------QLQDL-------TEEKGTLAGEIRDMKD------ 532
Cdd:pfam01576 423 eserqraelAEKLSKLQSELESVSSLLNEAEGKNIKLSKdvsslesQLQDTqellqeeTRQKLNLSTRLRQLEDernslq 502
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 533 -MLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRE- 610
Cdd:pfam01576 503 eQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEALEEGKKRLQRELEALTQQLEEKAAAYDKLEKTKNRLQQEl 582
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 611 --RLEEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQ---KKEECSKLEAQL 685
Cdd:pfam01576 583 ddLLVDLDHQRQLVSNLEKKQKKFDQMLAEEKAISARYAEERDRAEAEAREKETRALSLARALEEaleAKEELERTNKQL 662
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 686 KKQAEQLFNQMYNPAHNVEDDSRMNPEFADRIKQLDKEASYYRDECGKAQ--------------AEVDRLLEILKEVENE 751
Cdd:pfam01576 663 RAEMEDLVSSKDDVGKNVHELERSKRALEQQVEEMKTQLEELEDELQATEdaklrlevnmqalkAQFERDLQARDEQGEE 742
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 752 KNDK-DKKIAELESLTLRHMKDQNKKVANLKHNQQLEKKKNAQLLEEVRRREDSMAD-NSQHLQIEELMNALEKTRQELD 829
Cdd:pfam01576 743 KRRQlVKQVRELEAELEDERKQRAQAVAAKKKLELDLKELEAQIDAANKGREEAVKQlKKLQAQMKDLQRELEEARASRD 822
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 830 ATKARLASTQQSLAEKEAHLAnlrierrkQLEEILEMKQEALLAAISEKDANIALLELSASKKKKTQEEvmalKREKDRL 909
Cdd:pfam01576 823 EILAQSKESEKKLKNLEAELL--------QLQEDLAASERARRQAQQERDELADEIASGASGKSALQDE----KRRLEAR 890
|
730 740
....*....|....*....|..
gi 1570463013 910 VHQLKQQ---TQNRMKLMADNY 928
Cdd:pfam01576 891 IAQLEEEleeEQSNTELLNDRL 912
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
474-696 |
2.11e-05 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 48.86 E-value: 2.11e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 474 LKESLTAKEQRA----AILQTEVDALRLRLEEKEsflnkktKQLQDLTEEKGTLAGEirdmkdmlevkeRKINVLQKKIE 549
Cdd:COG3206 162 LEQNLELRREEArkalEFLEEQLPELRKELEEAE-------AALEEFRQKNGLVDLS------------EEAKLLLQQLS 222
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 550 NLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEAlsekeRIIERLKEQRERDDRERLEEIESFRKEN---KDLK 626
Cdd:COG3206 223 ELESQLAEARAELAEAEARLAALRAQLGSGPDALPELLQS-----PVIQQLRAQLAELEAELAELSARYTPNHpdvIALR 297
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1570463013 627 EKVNALQAEL-TEKESSLIDLKEHASSLASaglkRDSKLKSLEIAIEQKKEECSKLEAQLK------KQAEQLFNQM 696
Cdd:COG3206 298 AQIAALRAQLqQEAQRILASLEAELEALQA----REASLQAQLAQLEARLAELPELEAELRrlerevEVARELYESL 370
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
420-737 |
2.78e-05 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 48.58 E-value: 2.78e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 420 KQIEVYKSHSKFMKTKIDQLKQELSKKESELlALQTKLEtlsnqNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRL 499
Cdd:pfam17380 282 KAVSERQQQEKFEKMEQERLRQEKEEKAREV-ERRRKLE-----EAEKARQAEMDRQAAIYAEQERMAMERERELERIRQ 355
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 500 EEKEsflnkktKQLQDLTEEKgtLAGEIRDMKDMlevkERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNT 579
Cdd:pfam17380 356 EERK-------RELERIRQEE--IAMEISRMREL----ERLQMERQQKNERVRQELEAARKVKILEEERQRKIQQQKVEM 422
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 580 DTALATLEEALS------------EKERIieRLKEQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESSLIDLK 647
Cdd:pfam17380 423 EQIRAEQEEARQrevrrleeerarEMERV--RLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKE 500
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 648 EHASSlaSAGLKRDSKLKSLEIAIEQKKEECSKLEAQLKKQAEQLFNQMYNPAHNVEDDSRMNPEFADRIKQLDKEASYY 727
Cdd:pfam17380 501 LEERK--QAMIEEERKRKLLEKEMEERQKAIYEEERRREAEEERRKQQEMEERRRIQEQMRKATEERSRLEAMEREREMM 578
|
330
....*....|..
gi 1570463013 728 RD--ECGKAQAE 737
Cdd:pfam17380 579 RQivESEKARAE 590
|
|
| ClyA_Cry6Aa-like |
cd22656 |
Bacillus thuringiensis crystal 6Aa (Cry6Aa) toxin, and similar proteins; This model includes ... |
416-592 |
3.33e-05 |
|
Bacillus thuringiensis crystal 6Aa (Cry6Aa) toxin, and similar proteins; This model includes pesticidal Cry6Aa toxin from Bacillus thuringiensis, one of the many parasporal crystal (Cry) toxins produced during the sporulation phase of growth. Many of these proteins are toxic to numerous insect species and have been effectively used as proteinaceous insecticides to directly kill insect pests; some have been used to control insect growth on transgenic agricultural plants. Cry6Aa exists as a protoxin, which is activated by cleavage using trypsin. Structure studies for Cry6Aa support a mechanism of action by pore formation, similar to cytolysin A (ClyA)-type alpha pore-forming toxins (alpha-PFTs) such as HblB, and bioassay and mutation studies show that Cry6Aa is an active pore-forming toxin. Cry6Aa shows atypical features compared to other members of alpha-PFTs, including internal repeat sequences and small loop regions within major alpha helices.
Pssm-ID: 439154 [Multi-domain] Cd Length: 309 Bit Score: 47.36 E-value: 3.33e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 416 EEEIKQIEVYKSHSKFMKTKIDQLKQELSKKESELLALQTKLETLSNQNSD--CKQHIEVLKESLtaKEQRAAILQtevd 493
Cdd:cd22656 124 DDLLKEAKKYQDKAAKVVDKLTDFENQTEKDQTALETLEKALKDLLTDEGGaiARKEIKDLQKEL--EKLNEEYAA---- 197
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 494 ALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKkienLQEQLRDKDKQLTNLKDRVKSLQ 573
Cdd:cd22656 198 KLKAKIDELKALIADDEAKLAAALRLIADLTAADTDLDNLLALIGPAIPALEK----LQGAWQAIATDLDSLKDLLEDDI 273
|
170
....*....|....*....
gi 1570463013 574 TDSSNTDTALATLEEALSE 592
Cdd:cd22656 274 SKIPAAILAKLELEKAIEK 292
|
|
| RecN |
COG0497 |
DNA repair ATPase RecN [Replication, recombination and repair]; |
468-692 |
4.39e-05 |
|
DNA repair ATPase RecN [Replication, recombination and repair];
Pssm-ID: 440263 [Multi-domain] Cd Length: 555 Bit Score: 47.76 E-value: 4.39e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 468 KQHIEVLKESLTAKEQRAAILQ---TEVDALRLRLEEKEsflnkktkqlqDLTEEKGTL--AGEIRD----MKDMLEVKE 538
Cdd:COG0497 171 KKELEELRADEAERARELDLLRfqlEELEAAALQPGEEE-----------ELEEERRRLsnAEKLREalqeALEALSGGE 239
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 539 RKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSlqtdssntdtALATLEEALSEKERIIERLkeqreRDDRERLEEIESF 618
Cdd:COG0497 240 GGALDLLGQALRALERLAEYDPSLAELAERLES----------ALIELEEAASELRRYLDSL-----EFDPERLEEVEER 304
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1570463013 619 RKENKDLKEKvnaLQAELTEkessLIDLKEHASslasaglKRDSKLKSLEIAIEQKKEECSKLEAQLKKQAEQL 692
Cdd:COG0497 305 LALLRRLARK---YGVTVEE----LLAYAEELR-------AELAELENSDERLEELEAELAEAEAELLEAAEKL 364
|
|
| PRK09039 |
PRK09039 |
peptidoglycan -binding protein; |
439-573 |
4.85e-05 |
|
peptidoglycan -binding protein;
Pssm-ID: 181619 [Multi-domain] Cd Length: 343 Bit Score: 46.88 E-value: 4.85e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 439 LKQELSKKESELLALQTKLETLSNQnsdckqhievlkesLTAKEQRAAILQTEVDALRLRLEEKES-------FLNKKTK 511
Cdd:PRK09039 44 LSREISGKDSALDRLNSQIAELADL--------------LSLERQGNQDLQDSVANLRASLSAAEAersrlqaLLAELAG 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 512 QLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQL------------RDKDKQL----------TNLKDRV 569
Cdd:PRK09039 110 AGAAAEGRAGELAQELDSEKQVSARALAQVELLNQQIAALRRQLaaleaaldasekRDRESQAkiadlgrrlnVALAQRV 189
|
....
gi 1570463013 570 KSLQ 573
Cdd:PRK09039 190 QELN 193
|
|
| PRK05771 |
PRK05771 |
V-type ATP synthase subunit I; Validated |
381-626 |
5.29e-05 |
|
V-type ATP synthase subunit I; Validated
Pssm-ID: 235600 [Multi-domain] Cd Length: 646 Bit Score: 47.61 E-value: 5.29e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 381 EMKDTKIASLERNIRDLEDEIQMLkanGVLNTEDREEEIKQIEVYKSHSKFMKTK--IDQLKQELSKKESELLALQT-KL 457
Cdd:PRK05771 5 RMKKVLIVTLKSYKDEVLEALHEL---GVVHIEDLKEELSNERLRKLRSLLTKLSeaLDKLRSYLPKLNPLREEKKKvSV 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 458 ETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKqLQDLTEEKGT--LAGEI-RDMKDML 534
Cdd:PRK05771 82 KSLEELIKDVEEELEKIEKEIKELEEEISELENEIKELEQEIERLEPWGNFDLD-LSLLLGFKYVsvFVGTVpEDKLEEL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 535 EVKERKINVLQKKIE---------NLQEQLRDKDKQLtnLKDRVKSLQTDSSNT-DTALATLEEALSEKERIIERLKeqr 604
Cdd:PRK05771 161 KLESDVENVEYISTDkgyvyvvvvVLKELSDEVEEEL--KKLGFERLELEEEGTpSELIREIKEELEEIEKERESLL--- 235
|
250 260
....*....|....*....|..
gi 1570463013 605 erddrerlEEIESFRKENKDLK 626
Cdd:PRK05771 236 --------EELKELAKKYLEEL 249
|
|
| HEC1 |
COG5185 |
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ... |
496-927 |
5.43e-05 |
|
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 444066 [Multi-domain] Cd Length: 594 Bit Score: 47.26 E-value: 5.43e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 496 RLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQtD 575
Cdd:COG5185 162 KDIFGKLTQELNQNLKKLEIFGLTLGLLKGISELKKAEPSGTVNSIKESETGNLGSESTLLEKAKEIINIEEALKGFQ-D 240
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 576 SSNTDTALATLEEALSEKERIIERLKEQRERDDRERLEEIEsfrKENKDLKEKVNALQAELTEKESSlIDLKEHASSLaS 655
Cdd:COG5185 241 PESELEDLAQTSDKLEKLVEQNTDLRLEKLGENAESSKRLN---ENANNLIKQFENTKEKIAEYTKS-IDIKKATESL-E 315
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 656 AGLKRDSKLKSLEIAIEQKKEECSKLEAQLKKQAEQLFNQMynpahNVEDDSRMNPEFADRIKQLDKEAsyyrDECGKAQ 735
Cdd:COG5185 316 EQLAAAEAEQELEESKRETETGIQNLTAEIEQGQESLTENL-----EAIKEEIENIVGEVELSKSSEEL----DSFKDTI 386
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 736 AEV-DRLLEILKEVENEKNDKDKKIAELESLTLRHMKDQNKKVANLKHNQQLEKKKNAQLLEEVRRREDSMADNSQHLQI 814
Cdd:COG5185 387 ESTkESLDEIPQNQRGYAQEILATLEDTLKAADRQIEELQRQIEQATSSNEEVSKLLNELISELNKVMREADEESQSRLE 466
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 815 EELMNALEKTRQELDATKARLASTQQSLAEKEAHLANLRIERRKQLE----EILEMKQEALLAAISEKDANIALLELSAS 890
Cdd:COG5185 467 EAYDEINRSVRSKKEDLNEELTQIESRVSTLKATLEKLRAKLERQLEgvrsKLDQVAESLKDFMRARGYAHILALENLIP 546
|
410 420 430
....*....|....*....|....*....|....*...
gi 1570463013 891 KKKKTQEEVMALKR-EKDRLVHQLKQQTQNRMKLMADN 927
Cdd:COG5185 547 ASELIQASNAKTDGqAANLRTAVIDELTQYLSTIESQQ 584
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
149-383 |
5.50e-05 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 47.07 E-value: 5.50e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 149 DLQAQLKELQRENDLLRKELDIKDSKLGSSMNSIKTFWSPELKKERVLRKEEaARMSVLKEQMRVSHEENQHLQLTIQAL 228
Cdd:COG4942 24 EAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALE-QELAALEAELAELEKEIAELRAELEAQ 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 229 QDELRTQ----------RDLNHLLQQESGNRGAEHFTIelteenFRRLQAEHDRQAKELFLLRKTLEEMELRIETQKQTL 298
Cdd:COG4942 103 KEELAELlralyrlgrqPPLALLLSPEDFLDAVRRLQY------LKYLAPARREQAEELRADLAELAALRAELEAERAEL 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 299 NARDESIKKLLEMLQSkglpsksleDDNERTRRMAEAESQVSHLEVILDQKEKENIHLREELHRRSQLQPEPAKTKALQT 378
Cdd:COG4942 177 EALLAELEEERAALEA---------LKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAG 247
|
....*
gi 1570463013 379 VIEMK 383
Cdd:COG4942 248 FAALK 252
|
|
| HCR |
pfam07111 |
Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha ... |
264-916 |
5.70e-05 |
|
Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha helical coiled-coil rod HCR proteins. The function of HCR is unknown but it has been implicated in psoriasis in humans and is thought to affect keratinocyte proliferation.
Pssm-ID: 284517 [Multi-domain] Cd Length: 749 Bit Score: 47.44 E-value: 5.70e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 264 RRLQaEHDRQAKELFLLRKTLEEMELRIETQKQTLNArdesikklLEMLQSKGlpsksleddnertrrMAEAESQVSHL- 342
Cdd:pfam07111 70 RQLQ-ELRRLEEEVRLLRETSLQQKMRLEAQAMELDA--------LAVAEKAG---------------QAEAEGLRAALa 125
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 343 --EVILDQKEKENIHLREELHRRSQLQPEpAKTKALQTVIEMKDTKIASLERNIRDLEDEiqmlkangvlntedREEEIK 420
Cdd:pfam07111 126 gaEMVRKNLEEGSQRELEEIQRLHQEQLS-SLTQAHEEALSSLTSKAEGLEKSLNSLETK--------------RAGEAK 190
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 421 QIEVYKSHSkfmktkiDQLKQELSKKESELLALQTKLETLSN----------QNSDCKQHIEVLKESLTAKEQRAAILQT 490
Cdd:pfam07111 191 QLAEAQKEA-------ELLRKQLSKTQEELEAQVTLVESLRKyvgeqvppevHSQTWELERQELLDTMQHLQEDRADLQA 263
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 491 EVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEI-RDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQltnLKDRV 569
Cdd:pfam07111 264 TVELLQVRVQSLTHMLALQEEELTRKIQPSDSLEPEFpKKCRSLLNRWREKVFALMVQLKAQDLEHRDSVKQ---LRGQV 340
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 570 KSLQTDSSNTDTALATLEEALSEK--ERIIERLKEQRERDDRERLEEIESFRKENKD-----LKEKVNALQAELTEKESS 642
Cdd:pfam07111 341 AELQEQVTSQSQEQAILQRALQDKaaEVEVERMSAKGLQMELSRAQEARRRQQQQTAsaeeqLKFVVNAMSSTQIWLETT 420
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 643 LIDLKEHASSLASA------GLKRDSKLKSL---EIAIEQKKEECS-------KLEAQLKKQAEQLfnqmynpahnVEDD 706
Cdd:pfam07111 421 MTRVEQAVARIPSLsnrlsyAVRKVHTIKGLmarKVALAQLRQESCpppppapPVDADLSLELEQL----------REER 490
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 707 SRMNPEFADRIKQLDKEASYYRDEcgkAQAEVDRLLEILKEVENEKNDKDKKIAELesltlrhmkdqNKKVANLKHNQQL 786
Cdd:pfam07111 491 NRLDAELQLSAHLIQQEVGRAREQ---GEAERQQLSEVAQQLEQELQRAQESLASV-----------GQQLEVARQGQQE 556
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 787 EKKKNAQLLEEVRRREDSMAdnsQHLQiEELMNALEKTRQELDATKARLASTqqslaekeahlanlrieRRKQLEEILEM 866
Cdd:pfam07111 557 STEEAASLRQELTQQQEIYG---QALQ-EKVAEVETRLREQLSDTKRRLNEA-----------------RREQAKAVVSL 615
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|....
gi 1570463013 867 KQEALLAAiSEKDANIALLELSASKKK----KTQEEVMALKREKDRLVHQLKQQ 916
Cdd:pfam07111 616 RQIQHRAT-QEKERNQELRRLQDEARKeegqRLARRVQELERDKNLMLATLQQE 668
|
|
| Crescentin |
pfam19220 |
Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament ... |
230-639 |
6.53e-05 |
|
Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament proteins, named crescentin, whose cytoskeletal function is required for the vibrioid and helical shapes of Caulobacter crescentus. Without crescentin, the cells adopt a straight-rod morphology. Crescentin has characteriztic features of IF proteins including the ability to assemble into filaments in vitro without energy or cofactor requirements. In vivo, crescentin forms a helical structure that colocalizes with the inner cell curvatures beneath the cytoplasmic membrane.
Pssm-ID: 437057 [Multi-domain] Cd Length: 401 Bit Score: 46.60 E-value: 6.53e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 230 DELRTQRD----LNHLLQQESGNRGAEHFTIELTEENFRRLQAEHDRQAKELFLLRKTLEEMELRIETQKQTLNARDESI 305
Cdd:pfam19220 20 EDLRSLKAdfsqLIEPIEAILRELPQAKSRLLELEALLAQERAAYGKLRRELAGLTRRLSAAEGELEELVARLAKLEAAL 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 306 KkllemlqskglpskSLEDDNERTR-RMAEAESQVSHLEVILDQKEKENIHLREELhrrsqlqpepaktKALQTVIEMKD 384
Cdd:pfam19220 100 R--------------EAEAAKEELRiELRDKTAQAEALERQLAAETEQNRALEEEN-------------KALREEAQAAE 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 385 TKIASLERNIRDLEDEIQMLKANGVLNTEDREEEIKQIEVYKSHSKFMKTKIDQLKQELSKKESELLALQTKLETLSNQn 464
Cdd:pfam19220 153 KALQRAEGELATARERLALLEQENRRLQALSEEQAAELAELTRRLAELETQLDATRARLRALEGQLAAEQAERERAEAQ- 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 465 sdckqhievlkeSLTAKEQraaiLQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVL 544
Cdd:pfam19220 232 ------------LEEAVEA----HRAERASLRMKLEALTARAAATEQLLAEARNQLRDRDEAIRAAERRLKEASIERDTL 295
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 545 QKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRERLEEIESFRKENKD 624
Cdd:pfam19220 296 ERRLAGLEADLERRTQQFQEMQRARAELEERAEMLTKALAAKDAALERAEERIASLSDRIAELTKRFEVERAALEQANRR 375
|
410
....*....|....*
gi 1570463013 625 LKEkvnALQAELTEK 639
Cdd:pfam19220 376 LKE---ELQRERAER 387
|
|
| PRK05771 |
PRK05771 |
V-type ATP synthase subunit I; Validated |
344-595 |
6.66e-05 |
|
V-type ATP synthase subunit I; Validated
Pssm-ID: 235600 [Multi-domain] Cd Length: 646 Bit Score: 47.23 E-value: 6.66e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 344 VILDQKEKENIhlrEELHRRSQLQPEPAKTkalqtviEMKDTKIASLERNIRDLEDEIQMLKAngVLNTEDREEEIKQIE 423
Cdd:PRK05771 12 VTLKSYKDEVL---EALHELGVVHIEDLKE-------ELSNERLRKLRSLLTKLSEALDKLRS--YLPKLNPLREEKKKV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 424 VYKSHSKFmktkIDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLK--ESLTAKEQRA-----------AILQT 490
Cdd:PRK05771 80 SVKSLEEL----IKDVEEELEKIEKEIKELEEEISELENEIKELEQEIERLEpwGNFDLDLSLLlgfkyvsvfvgTVPED 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 491 EVDALRLRLEEKESFLNKKTKQ-----LQDLTEEKGTLAGEIRDM-------------KDMLEVKERKINVLQKKIENLQ 552
Cdd:PRK05771 156 KLEELKLESDVENVEYISTDKGyvyvvVVVLKELSDEVEEELKKLgferleleeegtpSELIREIKEELEEIEKERESLL 235
|
250 260 270 280
....*....|....*....|....*....|....*....|...
gi 1570463013 553 EQLRDKDKQLTNLKdrvkslqtdssntdtaLATLEEALSEKER 595
Cdd:PRK05771 236 EELKELAKKYLEEL----------------LALYEYLEIELER 262
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
372-594 |
7.50e-05 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 46.36 E-value: 7.50e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 372 KTKALQTVIEMKDTKIASLERNIRDLEDEIQMLKANgvlnTEDREEEIKQIEvykshskfmkTKIDQLKQELSKKESELL 451
Cdd:COG3883 17 QIQAKQKELSELQAELEAAQAELDALQAELEELNEE----YNELQAELEALQ----------AEIDKLQAEIAEAEAEIE 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 452 ALQTKLETL---SNQNSDCKQHIEVLKESLTAKE--QRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGE 526
Cdd:COG3883 83 ERREELGERaraLYRSGGSVSYLDVLLGSESFSDflDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEAL 162
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1570463013 527 IRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKE 594
Cdd:COG3883 163 KAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAA 230
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
149-614 |
7.58e-05 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 47.24 E-value: 7.58e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 149 DLQAQLKELQRENDLLRKELDIKDSKLGSSMNSIKTFWSPELKKERVLRKEEAARMSVLKEQMRVSHEENQHLQLTIQAL 228
Cdd:COG1196 348 EAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELE 427
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 229 QDELRTQRDLNHLLQQESGNRGAEHFTIELTEENFRRLQA---EHDRQAKELFLLRKTLEEMELRIETQKQTLNARDESI 305
Cdd:COG1196 428 EALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAElleEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFL 507
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 306 KKLLEMLQSKGLPSKS-----LEDDNERTRRMAEAESQVSHLEVILDQKE---------KENIHLREELHRRSQLQPEPA 371
Cdd:COG1196 508 EGVKAALLLAGLRGLAgavavLIGVEAAYEAALEAALAAALQNIVVEDDEvaaaaieylKAAKAGRATFLPLDKIRARAA 587
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 372 KTKALQTVIEMKDTK-IASLERNIRDLEDEIQMLKANGVLNTEDREEEIKQI----EVYKSHSKFMKTKIDQLKQELSKK 446
Cdd:COG1196 588 LAAALARGAIGAAVDlVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAvtlaGRLREVTLEGEGGSAGGSLTGGSR 667
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 447 ESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGE 526
Cdd:COG1196 668 RELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEEL 747
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 527 IRDMKDMLEVKERKINVLQKKIENLQEQLRDK-------DKQLTNLKDRVKSLQTDssntdtaLATLEEALSEKERIIER 599
Cdd:COG1196 748 LEEEALEELPEPPDLEELERELERLEREIEALgpvnllaIEEYEELEERYDFLSEQ-------REDLEEARETLEEAIEE 820
|
490
....*....|....*
gi 1570463013 600 LKEQRerddRERLEE 614
Cdd:COG1196 821 IDRET----RERFLE 831
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
390-619 |
9.76e-05 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 46.43 E-value: 9.76e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 390 LERNIRDLEDEIQMLKANGVLNTEDREEEIKQIEVYKSHSKFMKTKIDQLKQELSKKESELLALQTKLETLSNQNSDCKQ 469
Cdd:pfam07888 36 LEECLQERAELLQAQEAANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSREKHEELEEKYKELSASSEELSE 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 470 HIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIE 549
Cdd:pfam07888 116 EKDALLAQRAAHEARIRELEEDIKTLTQRVLERETELERMKERAKKAGAQRKEEEAERKQLQAKLQQTEEELRSLSKEFQ 195
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1570463013 550 NLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERL--KEQRERDDRERLEEIESFR 619
Cdd:pfam07888 196 ELRNSLAQRDTQVLQLQDTITTLTQKLTTAHRKEAENEALLEELRSLQERLnaSERKVEGLGEELSSMAAQR 267
|
|
| Lebercilin |
pfam15619 |
Ciliary protein causing Leber congenital amaurosis disease; Lebercilin is a family of ... |
435-595 |
9.83e-05 |
|
Ciliary protein causing Leber congenital amaurosis disease; Lebercilin is a family of eukaryotic ciliary proteins. Mutations in the gene, LCA5, are implicated in the disease Leber congenital amaurosis. In photoreceptors, lebercilin is uniquely localized at the cilium that bridges the inner and outer segments. Lebercilin functions as an integral element of selective protein transport through photoreceptor cilia. Lebercilin specifically interacts with the intraflagellar transport (IFT), and disruption of IFT can lead to Leber congenital amaurosis.
Pssm-ID: 464776 [Multi-domain] Cd Length: 193 Bit Score: 44.51 E-value: 9.83e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 435 KIDQLKQELSKKESELLALQTKLETL--------------SNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLE 500
Cdd:pfam15619 12 KIKELQNELAELQSKLEELRKENRLLkrlqkrqekalgkyEGTESELPQLIARHNEEVRVLRERLRRLQEKERDLERKLK 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 501 EKESFL---NKKTKQLQDLTEEKG-----TLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRdkdKQLTNLKDRVKSL 572
Cdd:pfam15619 92 EKEAELlrlRDQLKRLEKLSEDKNlaereELQKKLEQLEAKLEDKDEKIQDLERKLELENKSFR---RQLAAEKKKHKEA 168
|
170 180
....*....|....*....|...
gi 1570463013 573 QTDSSNTDTALATLEEALSEKER 595
Cdd:pfam15619 169 QEEVKILQEEIERLQQKLKEKER 191
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
256-403 |
1.01e-04 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 46.31 E-value: 1.01e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 256 IELTEENFRrLQAEHDRQAKELfllRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKglpsksleddnertrrmaea 335
Cdd:PRK12704 60 LEAKEEIHK-LRNEFEKELRER---RNELQKLEKRLLQKEENLDRKLELLEKREEELEKK-------------------- 115
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1570463013 336 ESQVSHLEVILDQKEKE--NIH--LREELHRRSQLQPEPAKTKALQTVIEMKDTKIASLernIRDLEDEIQM 403
Cdd:PRK12704 116 EKELEQKQQELEKKEEEleELIeeQLQELERISGLTAEEAKEILLEKVEEEARHEAAVL---IKEIEEEAKE 184
|
|
| COG1340 |
COG1340 |
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]; |
471-791 |
1.23e-04 |
|
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
Pssm-ID: 440951 [Multi-domain] Cd Length: 297 Bit Score: 45.29 E-value: 1.23e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 471 IEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIEN 550
Cdd:COG1340 3 TDELSSSLEELEEKIEELREEIEELKEKRDELNEELKELAEKRDELNAQVKELREEAQELREKRDELNEKVKELKEERDE 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 551 LQEQLRDKDKQLTNLKDRVKSLQTDSSNtdtalatleealsekeriIERLKEQRERDDRERLEEIESFRKEnKDLKEKVN 630
Cdd:COG1340 83 LNEKLNELREELDELRKELAELNKAGGS------------------IDKLRKEIERLEWRQQTEVLSPEEE-KELVEKIK 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 631 ALQAELTEKESSlidlkehasslasagLKRDSKLKSLEIAIEQKKEECSKLEAQLKK---QAEQLFNQMynpahnvedds 707
Cdd:COG1340 144 ELEKELEKAKKA---------------LEKNEKLKELRAELKELRKEAEEIHKKIKElaeEAQELHEEM----------- 197
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 708 rmnPEFADRIKQLDKEASYYRDECGKAQAEVDRLLEILKEVENEKNDKDKKIAELESLTLRHMKDQNKKVANLKHNQQLE 787
Cdd:COG1340 198 ---IELYKEADELRKEADELHKEIVEAQEKADELHEEIIELQKELRELRKELKKLRKKQRALKREKEKEELEEKAEEIFE 274
|
....
gi 1570463013 788 KKKN 791
Cdd:COG1340 275 KLKK 278
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
346-502 |
1.25e-04 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 44.92 E-value: 1.25e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 346 LDQKEKENIHLREEL-HRRSQLQpepAKTKALQTVIEMKDTKIASLERNIRDLEDEIQMLKANgVLNTEDREEEIKQIEV 424
Cdd:COG1579 15 LDSELDRLEHRLKELpAELAELE---DELAALEARLEAAKTELEDLEKEIKRLELEIEEVEAR-IKKYEEQLGNVRNNKE 90
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1570463013 425 YKSHSKfmktKIDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEK 502
Cdd:COG1579 91 YEALQK----EIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAE 164
|
|
| EzrA |
pfam06160 |
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like ... |
387-639 |
1.30e-04 |
|
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like cell-division protein FtsZ polymerizes into a ring structure that establishes the location of the nascent division site. EzrA modulates the frequency and position of FtsZ ring formation. The structure contains 5 spectrin like alpha helical repeats.
Pssm-ID: 428797 [Multi-domain] Cd Length: 542 Bit Score: 46.00 E-value: 1.30e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 387 IASLERNIRDLEDEIQM----------LKANGVLN-----TEDREEEIKQI-EVYKSHSKFMKTKIDQLK---QELSKKE 447
Cdd:pfam06160 148 IDELEKQLAEIEEEFSQfeeltesgdyLEAREVLEkleeeTDALEELMEDIpPLYEELKTELPDQLEELKegyREMEEEG 227
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 448 SEL--LALQTKLETLSNQNSDCKQHIEVLK--------ESLTAK-EQRAAILQTEVDALRL---RLEEKESFLNKKTKQL 513
Cdd:pfam06160 228 YALehLNVDKEIQQLEEQLEENLALLENLEldeaeealEEIEERiDQLYDLLEKEVDAKKYvekNLPEIEDYLEHAEEQN 307
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 514 QDLTEEKGTL----------AGEIRDMKDMLEVKERKINVLQKKIEN-------LQEQLRDKDKQLTN-------LKDRV 569
Cdd:pfam06160 308 KELKEELERVqqsytlneneLERVRGLEKQLEELEKRYDEIVERLEEkevayseLQEELEEILEQLEEieeeqeeFKESL 387
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1570463013 570 KSLQTDSSNTDTALATLEEALSEKERIIERLkeqrerddreRLEEI-ESFRKENKDLKEKVNALQAELTEK 639
Cdd:pfam06160 388 QSLRKDELEAREKLDEFKLELREIKRLVEKS----------NLPGLpESYLDYFFDVSDEIEDLADELNEV 448
|
|
| PRK11281 |
PRK11281 |
mechanosensitive channel MscK; |
465-695 |
1.74e-04 |
|
mechanosensitive channel MscK;
Pssm-ID: 236892 [Multi-domain] Cd Length: 1113 Bit Score: 46.06 E-value: 1.74e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 465 SDCKQHIEVLKESLTAKEQRAAILQTevdalrlrLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMlevkerkinvl 544
Cdd:PRK11281 39 ADVQAQLDALNKQKLLEAEDKLVQQD--------LEQTLALLDKIDRQKEETEQLKQQLAQAPAKLRQA----------- 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 545 QKKIENLQEQLRDKDKQlTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRE------RLEEIESF 618
Cdd:PRK11281 100 QAELEALKDDNDEETRE-TLSTLSLRQLESRLAQTLDQLQNAQNDLAEYNSQLVSLQTQPERAQAAlyansqRLQQIRNL 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 619 RKENKDLKEKVNALQAELTEKESSLIDLK--------EHASSLASAG-LKRDskLKSLEIAIEQKKEEC------SKLEA 683
Cdd:PRK11281 179 LKGGKVGGKALRPSQRVLLQAEQALLNAQndlqrkslEGNTQLQDLLqKQRD--YLTARIQRLEHQLQLlqeainSKRLT 256
|
250
....*....|..
gi 1570463013 684 QLKKQAEQLFNQ 695
Cdd:PRK11281 257 LSEKTVQEAQSQ 268
|
|
| ClpA |
COG0542 |
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ... |
432-597 |
1.91e-04 |
|
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440308 [Multi-domain] Cd Length: 836 Bit Score: 45.84 E-value: 1.91e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 432 MKTKIDQLKQELSKKESELLALQTKLETLSnqnsdckqhievlKESLTAKEQRAAILQTEVDALRLRLEEKEsflnkktk 511
Cdd:COG0542 402 VRMEIDSKPEELDELERRLEQLEIEKEALK-------------KEQDEASFERLAELRDELAELEEELEALK-------- 460
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 512 qlQDLTEEKgTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDR--------------VKSLQTDSS 577
Cdd:COG0542 461 --ARWEAEK-ELIEEIQELKEELEQRYGKIPELEKELAELEEELAELAPLLREEVTEediaevvsrwtgipVGKLLEGER 537
|
170 180
....*....|....*....|
gi 1570463013 578 NTdtaLATLEEALseKERII 597
Cdd:COG0542 538 EK---LLNLEEEL--HERVI 552
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
498-768 |
2.09e-04 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 44.89 E-value: 2.09e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 498 RLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSS 577
Cdd:COG4372 32 QLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQEEAE 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 578 NTDTALATLEEALSEKERIIERLKEQRErddrERLEEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAG 657
Cdd:COG4372 112 ELQEELEELQKERQDLEQQRKQLEAQIA----ELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAEAEQALDE 187
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 658 LKRDSKLKSLEIAIEQKKEECSKLEAQLKKQAEQLFNQMYNPAHNVEDDSRMNPEFADRIKQLDKEASYYRDECGKAQAE 737
Cdd:COG4372 188 LLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELELAI 267
|
250 260 270
....*....|....*....|....*....|.
gi 1570463013 738 VDRLLEILKEVENEKNDKDKKIAELESLTLR 768
Cdd:COG4372 268 LVEKDTEEEELEIAALELEALEEAALELKLL 298
|
|
| DUF4618 |
pfam15397 |
Domain of unknown function (DUF4618); This family of proteins is found in eukaryotes. Proteins ... |
420-648 |
2.34e-04 |
|
Domain of unknown function (DUF4618); This family of proteins is found in eukaryotes. Proteins in this family are typically between 238 and 363 amino acids in length. There are two conserved sequence motifs: EYP and KCTPD.
Pssm-ID: 464704 [Multi-domain] Cd Length: 258 Bit Score: 44.17 E-value: 2.34e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 420 KQIEVYKSHSKFMKTKIDQLKQEL-------SKKESELLALQTKLETLsnqnsdckqhIEVLKESLtakeqraailQTEV 492
Cdd:pfam15397 6 TSLEELKKHEDFLTKLNLELIKAIqdtedstALKVRKLLQQYEKFGTI----------ISILEYSN----------KKQL 65
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 493 DALRLRLEEKESFLNKKTKQLQDlteekgtlagEIRDMKDMLEVKERKINVL-----------QKKIENLQEQLRD-KDK 560
Cdd:pfam15397 66 QQAKAELQEWEEKEESKLNKLEQ----------QLEQLNAKIQKTQEELNFLstykdkeypvkAVQIANLVRQLQQlKDS 135
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 561 QLTNLKDRVKSLQTDssntdtaLATLEEALSEKERII------------ERLKEQRERDDRERLEEIESFRKENKDLKEK 628
Cdd:pfam15397 136 QQDELDELEEMRRMV-------LESLSRKIQKKKEKIlsslaektlspyQESLLQKTRDNQVMLKEIEQFREFIDELEEE 208
|
250 260
....*....|....*....|
gi 1570463013 629 VNALQAELTEKESSLIDLKE 648
Cdd:pfam15397 209 IPKLKAEVQQLQAQRQEPRE 228
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
265-615 |
2.71e-04 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 45.29 E-value: 2.71e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 265 RLQAEHDRQAKELFLLRKTLEEmelrIETQKQTLNARDESIKKLLEMlqskglpsksleddNERTRRMAEAESQVSHLEV 344
Cdd:COG4913 614 ALEAELAELEEELAEAEERLEA----LEAELDALQERREALQRLAEY--------------SWDEIDVASAEREIAELEA 675
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 345 ILDQKEKENIHLREELHRRSQLQpepAKTKALQTVIEMKDTKIASLERNIRDLEDEIQMLKAN-----------GVLNTE 413
Cdd:COG4913 676 ELERLDASSDDLAALEEQLEELE---AELEELEEELDELKGEIGRLEKELEQAEEELDELQDRleaaedlarleLRALLE 752
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 414 DREEEIKQIEVYKSHSKFMKTKIDQLKQELSKKESELLALQTKLetlsnqNSDCKQHIEVLKESLTAKEQRAAILqTEVD 493
Cdd:COG4913 753 ERFAAALGDAVERELRENLEERIDALRARLNRAEEELERAMRAF------NREWPAETADLDADLESLPEYLALL-DRLE 825
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 494 ALRL-RLEEK-ESFLNKKTKQlqDLTEEKGTLAGEIRDMKDMLEvkerKIN-VLQKKIENLQE--QLRDKDKQLTNLKDR 568
Cdd:COG4913 826 EDGLpEYEERfKELLNENSIE--FVADLLSKLRRAIREIKERID----PLNdSLKRIPFGPGRylRLEARPRPDPEVREF 899
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|..
gi 1570463013 569 VKSLQTDSSNTDTAlatlEEALSEK-----ERIIERLKEQRERDDRERLEEI 615
Cdd:COG4913 900 RQELRAVTSGASLF----DEELSEArfaalKRLIERLRSEEEESDRRWRARV 947
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
582-692 |
3.18e-04 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 44.77 E-value: 3.18e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 582 ALATLEEALSEKERIIERLKEQRERDDRERLEEIEsfRKENKdLKEKVNALqaeltEKESSLIDLKEHASslasagLKRD 661
Cdd:PRK12704 51 AEAIKKEALLEAKEEIHKLRNEFEKELRERRNELQ--KLEKR-LLQKEENL-----DRKLELLEKREEEL------EKKE 116
|
90 100 110
....*....|....*....|....*....|.
gi 1570463013 662 SKLKSLEIAIEQKKEECSKLEAQLKKQAEQL 692
Cdd:PRK12704 117 KELEQKQQELEKKEEELEELIEEQLQELERI 147
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
733-918 |
3.58e-04 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 45.05 E-value: 3.58e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 733 KAQAEvdrLLEILKEVENEKNDKDKkiaeleSLTLRHMKDQNKKVANLkhnqQLEKKKNAQLLEEVRRREdsmadNSQHL 812
Cdd:TIGR02168 206 ERQAE---KAERYKELKAELRELEL------ALLVLRLEELREELEEL----QEELKEAEEELEELTAEL-----QELEE 267
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 813 QIEELMNALEKTRQELDATKARLASTQQSLAEKEAHLANLRiERRKQLEEILEMKQEALLAAISEKDANIALLELSASKK 892
Cdd:TIGR02168 268 KLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILR-ERLANLERQLEELEAQLEELESKLDELAEELAELEEKL 346
|
170 180
....*....|....*....|....*.
gi 1570463013 893 KKTQEEVMALKREKDRLVHQLKQQTQ 918
Cdd:TIGR02168 347 EELKEELESLEAELEELEAELEELES 372
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
230-566 |
3.72e-04 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 44.95 E-value: 3.72e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 230 DELRTQRDLnhlLQQESGNRGAEHFTIELTEENFRRLQAEHDRQA------KELFLLRKTLEEME---LRIETQKQTLNA 300
Cdd:PRK04863 789 EQLRAEREE---LAERYATLSFDVQKLQRLHQAFSRFIGSHLAVAfeadpeAELRQLNRRRVELEralADHESQEQQQRS 865
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 301 RDESIKKLLEMLQsKGLPSKSLEDDNERTRRMAEAESQVSHLEV----------ILDQKEKENIHLREELHRRSQLQPEP 370
Cdd:PRK04863 866 QLEQAKEGLSALN-RLLPRLNLLADETLADRVEEIREQLDEAEEakrfvqqhgnALAQLEPIVSVLQSDPEQFEQLKQDY 944
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 371 AKTKALQTVIEMKDTKIASLERNIRDL--EDEIQMLKANGVLNtedreeeikqievykshskfmktkiDQLKQELSKKES 448
Cdd:PRK04863 945 QQAQQTQRDAKQQAFALTEVVQRRAHFsyEDAAEMLAKNSDLN-------------------------EKLRQRLEQAEQ 999
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 449 ELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESflnkktKQLQDLTEEKGTLAGEIR 528
Cdd:PRK04863 1000 ERTRAREQLRQAQAQLAQYNQVLASLKSSYDAKRQMLQELKQELQDLGVPADSGAE------ERARARRDELHARLSANR 1073
|
330 340 350 360
....*....|....*....|....*....|....*....|..
gi 1570463013 529 DMKDMLEVK----ERKINVLQKKIENLQEQLRDKDKQLTNLK 566
Cdd:PRK04863 1074 SRRNQLEKQltfcEAEMDNLTKKLRKLERDYHEMREQVVNAK 1115
|
|
| GAS |
pfam13851 |
Growth-arrest specific micro-tubule binding; This family is the highly conserved central ... |
435-600 |
4.08e-04 |
|
Growth-arrest specific micro-tubule binding; This family is the highly conserved central region of a number of metazoan proteins referred to as growth-arrest proteins. In mouse, Gas8 is predominantly a testicular protein, whose expression is developmentally regulated during puberty and spermatogenesis. In humans, it is absent in infertile males who lack the ability to generate gametes. The localization of Gas8 in the motility apparatus of post-meiotic gametocytes and mature spermatozoa, together with the detection of Gas8 also in cilia at the apical surfaces of epithelial cells lining the pulmonary bronchi and Fallopian tubes suggests that the Gas8 protein may have a role in the functioning of motile cellular appendages. Gas8 is a microtubule-binding protein localized to regions of dynein regulation in mammalian cells.
Pssm-ID: 464001 [Multi-domain] Cd Length: 200 Bit Score: 42.97 E-value: 4.08e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 435 KIDQLKqelskkeSELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQ----------TEVDALRLRLEEKES 504
Cdd:pfam13851 27 LIKSLK-------EEIAELKKKEERNEKLMSEIQQENKRLTEPLQKAQEEVEELRkqlenyekdkQSLKNLKARLKVLEK 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 505 FLNKKTKQLQDLTEEKGTLAGEIRDMKDM-----LEVKER---KINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDS 576
Cdd:pfam13851 100 ELKDLKWEHEVLEQRFEKVERERDELYDKfeaaiQDVQQKtglKNLLLEKKLQALGETLEKKEAQLNEVLAAANLDPDAL 179
|
170 180
....*....|....*....|....
gi 1570463013 577 SNTDtalATLEEALSEKERIIERL 600
Cdd:pfam13851 180 QAVT---EKLEDVLESKNQLIKDL 200
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
601-859 |
4.10e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 43.98 E-value: 4.10e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 601 KEQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLasaglkrDSKLKSLEIAIEQKKEECSK 680
Cdd:COG4942 22 AAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRAL-------EQELAALEAELAELEKEIAE 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 681 LEAQLKKQAEQLFNQMYNPAHNVEDDSRMNPEFADRIKQLDKEASYYRdecgkaqaevdrllEILKEVENEKNDKDKKIA 760
Cdd:COG4942 95 LRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLK--------------YLAPARREQAEELRADLA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 761 ELESLtlrhmkdqnkkvanlkhNQQLEKKKNAQLLEEVRRREDSMADNSQHLQIEELMNALEKTRQELDATKARLASTQQ 840
Cdd:COG4942 161 ELAAL-----------------RAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAE 223
|
250
....*....|....*....
gi 1570463013 841 SLAEKEAHLANLRIERRKQ 859
Cdd:COG4942 224 ELEALIARLEAEAAAAAER 242
|
|
| PTZ00440 |
PTZ00440 |
reticulocyte binding protein 2-like protein; Provisional |
417-861 |
4.46e-04 |
|
reticulocyte binding protein 2-like protein; Provisional
Pssm-ID: 240419 [Multi-domain] Cd Length: 2722 Bit Score: 44.82 E-value: 4.46e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 417 EEIKQIEVYKSHSKFMKTKIDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLT-------AKEQRAAILQ 489
Cdd:PTZ00440 519 NNFKNIEDYYITIEGLKNEIEGLIELIKYYLQSIETLIKDEKLKRSMKNDIKNKIKYIEENVDhikdiisLNDEIDNIIQ 598
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 490 TEVDALRLRLEEKESFLNKKTKQLQDLTE-----EKGTLAGEIRDMKDMLEVKE---------RKINVLQKKIENLQEQL 555
Cdd:PTZ00440 599 QIEELINEALFNKEKFINEKNDLQEKVKYilnkfYKGDLQELLDELSHFLDDHKylyheakskEDLQTLLNTSKNEYEKL 678
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 556 rdKDKQLTNLKDRVKSLQTDSSNTdtalatleeaLSEKERIIERLKEQRERDDRERLEEIesfRKENKDLKEKVNALQAE 635
Cdd:PTZ00440 679 --EFMKSDNIDNIIKNLKKELQNL----------LSLKENIIKKQLNNIEQDISNSLNQY---TIKYNDLKSSIEEYKEE 743
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 636 LTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKkeecskleAQLKKQAEQLFNQMYNPAHNVEDDSRMNPEFAD 715
Cdd:PTZ00440 744 EEKLEVYKHQIINRKNEFILHLYENDKDLPDGKNTYEEF--------LQYKDTILNKENKISNDINILKENKKNNQDLLN 815
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 716 RIKQLDKEasyYRDECGKAQAEVDRLLEI---------LKEVENEKNDKDKKIaeleSLTLRHMKDQNKKVANLK--HNQ 784
Cdd:PTZ00440 816 SYNILIQK---LEAHTEKNDEELKQLLQKfptedenlnLKELEKEFNENNQIV----DNIIKDIENMNKNINIIKtlNIA 888
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 785 QLEKKKNAQLLEEVRRREDSMADN-SQHLQIEELMNALEKTRQE--LDATKARLASTQQSLAekEAHLANLRIERRKQLE 861
Cdd:PTZ00440 889 INRSNSNKQLVEHLLNNKIDLKNKlEQHMKIINTDNIIQKNEKLnlLNNLNKEKEKIEKQLS--DTKINNLKMQIEKTLE 966
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
150-805 |
4.48e-04 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 44.78 E-value: 4.48e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 150 LQAQLKELQ---RENDLLRKELDIKDSKLGSSMNSIKTFWSPELKKERVLRKEEAARMSvlkeqmrvsheenqHLQLTIQ 226
Cdd:pfam01576 410 LEGQLQELQarlSESERQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLES--------------QLQDTQE 475
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 227 ALQDELRTQRDLNHLLQQESGNRGAEHFTIELTEENFRRLQAEHDRQAKELFLLRKTLEEMELRIETQKQTLNARDESIK 306
Cdd:pfam01576 476 LLQEETRQKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEALEEGKKRLQRELE 555
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 307 KLLEMLQSKGLPSKSLEDDNERTRR-----MAEAESQVSHLEVILDQKEKENIHLREELHRRSQLQPEPAKTKALQtviE 381
Cdd:pfam01576 556 ALTQQLEEKAAAYDKLEKTKNRLQQelddlLVDLDHQRQLVSNLEKKQKKFDQMLAEEKAISARYAEERDRAEAEA---R 632
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 382 MKDTKIASLERNIRDLEDEIQML-KANGVLNTEDREEEIKQIEVYKS------HSKFMKTKIDQLKQELSKKESELLALQ 454
Cdd:pfam01576 633 EKETRALSLARALEEALEAKEELeRTNKQLRAEMEDLVSSKDDVGKNvhelerSKRALEQQVEEMKTQLEELEDELQATE 712
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 455 tkletlsnqnsDCKQHIEVLKESLTAKEQRAaiLQTEVD-------ALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEI 527
Cdd:pfam01576 713 -----------DAKLRLEVNMQALKAQFERD--LQARDEqgeekrrQLVKQVRELEAELEDERKQRAQAVAAKKKLELDL 779
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 528 RDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEE---ALSEKERIIERLKEQR 604
Cdd:pfam01576 780 KELEAQIDAANKGREEAVKQLKKLQAQMKDLQRELEEARASRDEILAQSKESEKKLKNLEAellQLQEDLAASERARRQA 859
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 605 ERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEECSKLEA- 683
Cdd:pfam01576 860 QQERDELADEIASGASGKSALQDEKRRLEARIAQLEEELEEEQSNTELLNDRLRKSTLQVEQLTTELAAERSTSQKSESa 939
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 684 --QLKKQAEQLFNQMYNPAHNVEDDSRMN-----PEFADRIKQLDKEASyYRDECGKAQAEVD-RLLEILKEVENEKNDK 755
Cdd:pfam01576 940 rqQLERQNKELKAKLQEMEGTVKSKFKSSiaaleAKIAQLEEQLEQESR-ERQAANKLVRRTEkKLKEVLLQVEDERRHA 1018
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|..
gi 1570463013 756 D--KKIAELESLTLRHMKDQNKKVANLKHNQQLEKKKNAQLLEEVRRREDSM 805
Cdd:pfam01576 1019 DqyKDQAEKGNSRMKQLKRQLEEAEEEASRANAARRKLQRELDDATESNESM 1070
|
|
| HMMR_N |
pfam15905 |
Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of ... |
420-547 |
4.88e-04 |
|
Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of eukaryotic hyaluronan-mediated motility receptor proteins. The protein is functionally associated with BRCA1 and thus predicted to be a common, low-penetrance breast cancer candidate.
Pssm-ID: 464932 [Multi-domain] Cd Length: 329 Bit Score: 43.65 E-value: 4.88e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 420 KQIEVYKSHSKFMKTKIDQLKQELSKKESE----------LLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQ 489
Cdd:pfam15905 184 GKLQVTQKNLEHSKGKVAQLEEKLVSTEKEkieeksetekLLEYITELSCVSEQVEKYKLDIAQLEELLKEKNDEIESLK 263
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1570463013 490 TEVDALRLRLEEKESFLNKKTKQLQDLTEEK--------GTLAGEIRDMKDMLEVKERKINVLQKK 547
Cdd:pfam15905 264 QSLEEKEQELSKQIKDLNEKCKLLESEKEELlreyeekeQTLNAELEELKEKLTLEEQEHQKLQQK 329
|
|
| Spc7 |
smart00787 |
Spc7 kinetochore protein; This domain is found in cell division proteins which are required ... |
495-635 |
4.95e-04 |
|
Spc7 kinetochore protein; This domain is found in cell division proteins which are required for kinetochore-spindle association.
Pssm-ID: 197874 [Multi-domain] Cd Length: 312 Bit Score: 43.47 E-value: 4.95e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 495 LRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDmlevkerkinVLQKKIENLQEQLRDKDK----QLTNLKDRVK 570
Cdd:smart00787 145 LKEGLDENLEGLKEDYKLLMKELELLNSIKPKLRDRKD----------ALEEELRQLKQLEDELEDcdptELDRAKEKLK 214
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1570463013 571 SLQTDSSNTDTALATLEEALSEKERIIERLKEQRErDDRERLEEIESFRKENKD--------LKEKVNALQAE 635
Cdd:smart00787 215 KLLQEIMIKVKKLEELEEELQELESKIEDLTNKKS-ELNTEIAEAEKKLEQCRGftfkeiekLKEQLKLLQSL 286
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
333-525 |
5.47e-04 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 43.67 E-value: 5.47e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 333 AEAESQVSHLEVILDQKEKENIHLREELhRRSQLQPEPAKTKALQTVIEMKDTK--IASLERNIRDLEDEIQMLKA---- 406
Cdd:COG3883 12 AFADPQIQAKQKELSELQAELEAAQAEL-DALQAELEELNEEYNELQAELEALQaeIDKLQAEIAEAEAEIEERREelge 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 407 -------NG--------VLNTEDREEEIKQIEVYKSHSKFMKTKIDQLKQELSKKESELLALQTKLETLSNQNSDCKQHI 471
Cdd:COG3883 91 raralyrSGgsvsyldvLLGSESFSDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAK 170
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 1570463013 472 EVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAG 525
Cdd:COG3883 171 AELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAA 224
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
715-917 |
6.21e-04 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 44.28 E-value: 6.21e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 715 DRIKQLDKEASYYRDEcgKAQAEVDRLLEILKEVENEKNDKDKKIAELESLTLRHmkdqNKKVANLKHNQQLEKKKNAQL 794
Cdd:TIGR02168 220 AELRELELALLVLRLE--ELREELEELQEELKEAEEELEELTAELQELEEKLEEL----RLEVSELEEEIEELQKELYAL 293
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 795 LEEVRRREdsmadnsqhLQIEELMNALEKTRQELDATKARLASTQQSLAEKEAHLAnlrierrkQLEEILEMKQEALLAA 874
Cdd:TIGR02168 294 ANEISRLE---------QQKQILRERLANLERQLEELEAQLEELESKLDELAEELA--------ELEEKLEELKEELESL 356
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 1570463013 875 ISEKDANIALLELSASKKKKTQEEVMALKREKDRLVHQLKQQT 917
Cdd:TIGR02168 357 EAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLN 399
|
|
| PRK12705 |
PRK12705 |
hypothetical protein; Provisional |
752-916 |
6.64e-04 |
|
hypothetical protein; Provisional
Pssm-ID: 237178 [Multi-domain] Cd Length: 508 Bit Score: 43.54 E-value: 6.64e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 752 KNDKDKKIAELESLTLRHMKDQNKKVANLKHNQQLEKKKNAQLLEEVRRREDSMADNSQHLQIEElmnALEKTRQELDAT 831
Cdd:PRK12705 27 KRQRLAKEAERILQEAQKEAEEKLEAALLEAKELLLRERNQQRQEARREREELQREEERLVQKEE---QLDARAEKLDNL 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 832 KARLASTQQSLAEKEAHLANLRIERRKQLEEILEMKQEALLAAISEKDANIALLELSASKKKKTQEEVMALKREKDRLVH 911
Cdd:PRK12705 104 ENQLEEREKALSARELELEELEKQLDNELYRVAGLTPEQARKLLLKLLDAELEEEKAQRVKKIEEEADLEAERKAQNILA 183
|
....*
gi 1570463013 912 QLKQQ 916
Cdd:PRK12705 184 QAMQR 188
|
|
| CagA_N |
pfam18971 |
CagA protein; The Helicobacter pylori type IV secretion effector CagA is a major bacterial ... |
495-799 |
6.83e-04 |
|
CagA protein; The Helicobacter pylori type IV secretion effector CagA is a major bacterial virulence determinant and critical for gastric carcinogenesis. X-ray crystallographic analysis of the N-terminal CagA fragment (residues 1-876) revealed that the region has a structure comprised of three discrete domains. Domain I constitutes a mobile CagA N terminus, while Domain II tethers CagA to the plasma membrane by interacting with membrane phosphatidylserine. Domain III interacts intramolecularly with the intrinsically disordered C-terminal region, and this interaction potentiates the pathogenic scaffold/hub function of CagA.
Pssm-ID: 408741 [Multi-domain] Cd Length: 876 Bit Score: 43.99 E-value: 6.83e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 495 LRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDM-KDMLEVKER-KINVLQKKIENLQEQLRDKDkqltNLKDRV-KS 571
Cdd:pfam18971 561 LENKLTAKGLSLQEANKLIKDFLSSNKELAGKALNFnKAVAEAKSTgNYDEVKKAQKDLEKSLRKRE----HLEKEVeKK 636
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 572 LQTDSSNTDTALATlEEALSEKERIIERLKEQRERDDRErLEEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEHAS 651
Cdd:pfam18971 637 LESKSGNKNKMEAK-AQANSQKDEIFALINKEANRDARA-IAYTQNLKGIKRELSDKLEKISKDLKDFSKSFDEFKNGKN 714
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 652 SLASaglKRDSKLKSLEIAIEQ---KKEECSKLE------AQLKKQAEQLFNQMYNPAHNVED---DSRMNPEFADRIKQ 719
Cdd:pfam18971 715 KDFS---KAEETLKALKGSVKDlgiNPEWISKVEnlnaalNEFKNGKNKDFSKVTQAKSDLENsvkDVIINQKVTDKVDN 791
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 720 LDKEASyyrdeCGKAQAEVDRLLEILkevenekndkdkkiAELESLTLRHMKDQNKKvanlkhNQQLEKKKNAQLLEEVR 799
Cdd:pfam18971 792 LNQAVS-----VAKAMGDFSRVEQVL--------------ADLKNFSKEQLAQQAQK------NEDFNTGKNSELYQSVK 846
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
155-449 |
7.52e-04 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 43.98 E-value: 7.52e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 155 KELQRENDLLRKELDIKDSKLGSSMNSIKTFWSPELKKERVLRKEEAARMSVlkEQMRVSHEENQHLQLTIQALQDELRT 234
Cdd:PTZ00121 1571 KAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKA--EELKKAEEEKKKVEQLKKKEAEEKKK 1648
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 235 QRDLNhllQQESGNRgaehftieLTEENFRRLQAEHDRQAKElflLRKTLEEMELRIE--TQKQTLNARDESIKKLLEML 312
Cdd:PTZ00121 1649 AEELK---KAEEENK--------IKAAEEAKKAEEDKKKAEE---AKKAEEDEKKAAEalKKEAEEAKKAEELKKKEAEE 1714
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 313 QSKGLPSKSLEDDN----ERTRRMAEAESQVSHlEVILDQKEKENI-HLREELHRRSQLQPEPAKTKALQTVIEMKDTKI 387
Cdd:PTZ00121 1715 KKKAEELKKAEEENkikaEEAKKEAEEDKKKAE-EAKKDEEEKKKIaHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRR 1793
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1570463013 388 ASLERNIRDLEDEIQMLKANGVLNT----EDREEEIKQIEVYKSHSKFMKTKIDQLKQELSKKESE 449
Cdd:PTZ00121 1794 MEVDKKIKDIFDNFANIIEGGKEGNlvinDSKEMEDSAIKEVADSKNMQLEEADAFEKHKFNKNNE 1859
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
434-916 |
7.88e-04 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 43.80 E-value: 7.88e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 434 TKIDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQraaILQTEVDALRLRLEEKESFLNKKTKQL 513
Cdd:TIGR00618 173 FPLDQYTQLALMEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQ---VLEKELKHLREALQQTQQSHAYLTQKR 249
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 514 QDLTE--EKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLR-------------DKDKQLTNLKDRVKSLQTDSSN 578
Cdd:TIGR00618 250 EAQEEqlKKQQLLKQLRARIEELRAQEAVLEETQERINRARKAAPlaahikavtqieqQAQRIHTELQSKMRSRAKLLMK 329
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 579 TDTALATlEEALSEKERIIERLkeQRERDDRERLEEIESFRKENKD----LKEKVNALQAELT---EKESSLIDLKEHAS 651
Cdd:TIGR00618 330 RAAHVKQ-QSSIEEQRRLLQTL--HSQEIHIRDAHEVATSIREISCqqhtLTQHIHTLQQQKTtltQKLQSLCKELDILQ 406
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 652 SLASAGLKRDSKLKSLEI--AIEQKKEECSKLEAQLKKQAEQLFNQ---MYNPAHNveddsRMNPEFADRIKQLDKEASY 726
Cdd:TIGR00618 407 REQATIDTRTSAFRDLQGqlAHAKKQQELQQRYAELCAAAITCTAQcekLEKIHLQ-----ESAQSLKEREQQLQTKEQI 481
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 727 YRDECGKAQAEVDRLLEI------LKEVENEKNDKDKKIAELESLTLR------HMKDQNKKVANLKHNQQLEKKKNAQL 794
Cdd:TIGR00618 482 HLQETRKKAVVLARLLELqeepcpLCGSCIHPNPARQDIDNPGPLTRRmqrgeqTYAQLETSEEDVYHQLTSERKQRASL 561
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 795 LEEVRRREDSMADNSQhlQIEELMNALEKTRQELDatkaRLASTQQSLAEKEAHLANLRIERRKQLEEILEMKQEALLAA 874
Cdd:TIGR00618 562 KEQMQEIQQSFSILTQ--CDNRSKEDIPNLQNITV----RLQDLTEKLSEAEDMLACEQHALLRKLQPEQDLQDVRLHLQ 635
|
490 500 510 520
....*....|....*....|....*....|....*....|..
gi 1570463013 875 ISEKDANIALLELSASKKKKTQEEVmalkREKDRLVHQLKQQ 916
Cdd:TIGR00618 636 QCSQELALKLTALHALQLTLTQERV----REHALSIRVLPKE 673
|
|
| ClyA_Cry6Aa-like |
cd22656 |
Bacillus thuringiensis crystal 6Aa (Cry6Aa) toxin, and similar proteins; This model includes ... |
402-588 |
9.43e-04 |
|
Bacillus thuringiensis crystal 6Aa (Cry6Aa) toxin, and similar proteins; This model includes pesticidal Cry6Aa toxin from Bacillus thuringiensis, one of the many parasporal crystal (Cry) toxins produced during the sporulation phase of growth. Many of these proteins are toxic to numerous insect species and have been effectively used as proteinaceous insecticides to directly kill insect pests; some have been used to control insect growth on transgenic agricultural plants. Cry6Aa exists as a protoxin, which is activated by cleavage using trypsin. Structure studies for Cry6Aa support a mechanism of action by pore formation, similar to cytolysin A (ClyA)-type alpha pore-forming toxins (alpha-PFTs) such as HblB, and bioassay and mutation studies show that Cry6Aa is an active pore-forming toxin. Cry6Aa shows atypical features compared to other members of alpha-PFTs, including internal repeat sequences and small loop regions within major alpha helices.
Pssm-ID: 439154 [Multi-domain] Cd Length: 309 Bit Score: 42.74 E-value: 9.43e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 402 QMLKANGVLNTEDREEEIKQievyksHSKFMKTKIDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAK 481
Cdd:cd22656 95 EILELIDDLADATDDEELEE------AKKTIKALLDDLLKEAKKYQDKAAKVVDKLTDFENQTEKDQTALETLEKALKDL 168
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 482 --EQRAAILQTEVDALRlrleekesflnkktKQLQDLTEEkgtlagEIRDMKDmlevkerKINVLQKKIENLQEQLRDKD 559
Cdd:cd22656 169 ltDEGGAIARKEIKDLQ--------------KELEKLNEE------YAAKLKA-------KIDELKALIADDEAKLAAAL 221
|
170 180
....*....|....*....|....*....
gi 1570463013 560 KQLTNLKDRVKSLQTDSSNTDTALATLEE 588
Cdd:cd22656 222 RLIADLTAADTDLDNLLALIGPAIPALEK 250
|
|
| ClpA |
COG0542 |
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ... |
580-686 |
1.18e-03 |
|
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440308 [Multi-domain] Cd Length: 836 Bit Score: 43.15 E-value: 1.18e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 580 DTALA-------TLEEALSEKERIIERLKEQRER----DDRERLEEIESFRKENKDLKEKVNALQAELtEKESSLIdlkE 648
Cdd:COG0542 396 DEAAArvrmeidSKPEELDELERRLEQLEIEKEAlkkeQDEASFERLAELRDELAELEEELEALKARW-EAEKELI---E 471
|
90 100 110
....*....|....*....|....*....|....*...
gi 1570463013 649 HASSLASAGLKRDSKLKSLEIAIEQKKEECSKLEAQLK 686
Cdd:COG0542 472 EIQELKEELEQRYGKIPELEKELAELEEELAELAPLLR 509
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
784-923 |
1.28e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 42.44 E-value: 1.28e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 784 QQLEKKKNAQLLEEVRRREDSMADNSQHLQ--IEELMNALEKTRQELDATKARLASTQQSLAEKEAHLANLRIER---RK 858
Cdd:COG4942 18 QADAAAEAEAELEQLQQEIAELEKELAALKkeEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIaelRA 97
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1570463013 859 QLEEILEMKQEALLAAISEKDANIALLELSASKKKKTQEEVMALKREKDRLVHQLKQQTQNRMKL 923
Cdd:COG4942 98 ELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAEL 162
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
714-907 |
1.49e-03 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 42.70 E-value: 1.49e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 714 ADRIKQLDKEASYYRDECGKAQAEVDRLLEILKEVENEKNDKDkkIAELESLTLRHMKDQNKKVANLKHNQQLEKKKNAQ 793
Cdd:COG3206 167 ELRREEARKALEFLEEQLPELRKELEEAEAALEEFRQKNGLVD--LSEEAKLLLQQLSELESQLAEARAELAEAEARLAA 244
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 794 LLEEVRRREDSMADNSQHLQIEELMNALEKTRQELDATKARLASTQQSLAEKEAHLANLRIERRKQLEEIL---EMKQEA 870
Cdd:COG3206 245 LRAQLGSGPDALPELLQSPVIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQRILaslEAELEA 324
|
170 180 190
....*....|....*....|....*....|....*..
gi 1570463013 871 LLAAISEKDANIALLELSASKKKKTQEEVMALKREKD 907
Cdd:COG3206 325 LQAREASLQAQLAQLEARLAELPELEAELRRLEREVE 361
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
227-573 |
1.69e-03 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 42.90 E-value: 1.69e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 227 ALQDELRTQRDlnhllqQESGNRGAEHFTIELTEENFRRLQAEHDRQAKELFLLRKTLEEMEL---RIETQKQTL----- 298
Cdd:pfam12128 597 ASEEELRERLD------KAEEALQSAREKQAAAEEQLVQANGELEKASREETFARTALKNARLdlrRLFDEKQSEkdkkn 670
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 299 NARDESIKKLLEMLQSKGLPSKSLEDDNE-------RTRRMAEAESQVSHLEVILDQKEKENIHLREELHRRSQLQpepA 371
Cdd:pfam12128 671 KALAERKDSANERLNSLEAQLKQLDKKHQawleeqkEQKREARTEKQAYWQVVEGALDAQLALLKAAIAARRSGAK---A 747
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 372 KTKALQTviEMKDT---------KIASLERNIRDLEDEIQMLKANG--VLNTED--REEEIKQIEVYKSHSKFMKTKIDQ 438
Cdd:pfam12128 748 ELKALET--WYKRDlaslgvdpdVIAKLKREIRTLERKIERIAVRRqeVLRYFDwyQETWLQRRPRLATQLSNIERAISE 825
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 439 LKQELSKKESELLALQTKLETlsNQNSDCKQHIEvLKESLTAKEQRAAILQT-EVDALRLRLEEKESFLNKKTKQLQDLT 517
Cdd:pfam12128 826 LQQQLARLIADTKLRRAKLEM--ERKASEKQQVR-LSENLRGLRCEMSKLATlKEDANSEQAQGSIGERLAQLEDLKLKR 902
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*..
gi 1570463013 518 E-EKGTLAGEIRDMKDMLEVKERkiNVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQ 573
Cdd:pfam12128 903 DyLSESVKKYVEHFKNVIADHSG--SGLAETWESLREEDHYQNDKGIRLLDYRKLVP 957
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
587-687 |
1.77e-03 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 42.54 E-value: 1.77e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 587 EEALSEKERIIERLKEQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGL-------- 658
Cdd:COG2433 387 EKELPEEEPEAEREKEHEERELTEEEEEIRRLEEQVERLEAEVEELEAELEEKDERIERLERELSEARSEERreirkdre 466
|
90 100 110
....*....|....*....|....*....|.
gi 1570463013 659 --KRDSKLKSLEIAIEQKKEECSKLEAQLKK 687
Cdd:COG2433 467 isRLDREIERLERELEEERERIEELKRKLER 497
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
321-554 |
2.06e-03 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 42.31 E-value: 2.06e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 321 SLEDDNERTRRMAEA-ESQVSHLEVILDQKEKEnihlREELHRRSQLQPEPAKTKALQTVIEMKDTKIASLERNIRDLED 399
Cdd:COG3206 165 NLELRREEARKALEFlEEQLPELRKELEEAEAA----LEEFRQKNGLVDLSEEAKLLLQQLSELESQLAEARAELAEAEA 240
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 400 EIQMLKANGVLNtEDREEEIKQIEVYKShskfMKTKIDQLKQELSKKESELLALQTKLETLSNQnsdckqhIEVLKESLT 479
Cdd:COG3206 241 RLAALRAQLGSG-PDALPELLQSPVIQQ----LRAQLAELEAELAELSARYTPNHPDVIALRAQ-------IAALRAQLQ 308
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1570463013 480 AKEQRAAI-LQTEVDALRLRLEEKESFLNKKTKQLQDLTEekgtLAGEIRDMKDMLEVKERKINVLQKKIENLQEQ 554
Cdd:COG3206 309 QEAQRILAsLEAELEALQAREASLQAQLAQLEARLAELPE----LEAELRRLEREVEVARELYESLLQRLEEARLA 380
|
|
| Surf_Exclu_PgrA |
TIGR04320 |
SEC10/PgrA surface exclusion domain; This model describes a conserved domain found in surface ... |
541-643 |
2.69e-03 |
|
SEC10/PgrA surface exclusion domain; This model describes a conserved domain found in surface proteins of a number of Firmutes. Many members have LPXTG C-terminal anchoring motifs and a substantial number have the KxYKxGKxW putative sorting signal at the N-terminus. The tetracycline resistance plasmid pCF10 in Enterococcus faecalis promotes conjugal plasmid transfer in response to sex pheromones, but PgrA/Sec10 encoded by that plasmid, a member of this family, specifically inhibits the ability of cells to receive homologous plasmids. The phenomenon is called surface exclusion.
Pssm-ID: 275124 [Multi-domain] Cd Length: 356 Bit Score: 41.64 E-value: 2.69e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 541 INVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRERLEEIESfrk 620
Cdd:TIGR04320 256 LAALQAKLATAQADLAAAQTALNTAQAALTSAQTAYAAAQAALATAQKELANAQAQALQTAQNNLATAQAALANAEA--- 332
|
90 100
....*....|....*....|...
gi 1570463013 621 ENKDLKEKVNALQAELTEKESSL 643
Cdd:TIGR04320 333 RLAKAKEALANLNADLAKKQAAL 355
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
783-926 |
2.72e-03 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 41.35 E-value: 2.72e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 783 NQQLEKKKNAQLLEEVRRREDSMADnsqhlQIEELMNALEKTRQELDATKARLASTQQSLAEKEAHLANLRIERRKQ--- 859
Cdd:COG3883 20 AKQKELSELQAELEAAQAELDALQA-----ELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERara 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 860 ----------LEEILE-------MKQEALLAAISEKDANI--------ALLELSASKKKKTQEEVMALKREKDRLVHQLK 914
Cdd:COG3883 95 lyrsggsvsyLDVLLGsesfsdfLDRLSALSKIADADADLleelkadkAELEAKKAELEAKLAELEALKAELEAAKAELE 174
|
170
....*....|..
gi 1570463013 915 QQTQNRMKLMAD 926
Cdd:COG3883 175 AQQAEQEALLAQ 186
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
673-898 |
3.07e-03 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 41.65 E-value: 3.07e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 673 QKKEECSKLEAQ-LKKQAEQLfnqmynpAHNVEDDSRMNPEFADRIKQLDKEASYYRDECGKA---QAEVDRLLEILKEV 748
Cdd:pfam17380 288 QQQEKFEKMEQErLRQEKEEK-------AREVERRRKLEEAEKARQAEMDRQAAIYAEQERMAmerERELERIRQEERKR 360
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 749 ENEKNDKDKKIAELESLTLRHMKDQNKKVANLKHNQQLEKKKNAQLLEEVRRREDSMADNSQHLQIEELMNALEKTRQEL 828
Cdd:pfam17380 361 ELERIRQEEIAMEISRMRELERLQMERQQKNERVRQELEAARKVKILEEERQRKIQQQKVEMEQIRAEQEEARQREVRRL 440
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1570463013 829 DATKAR-LASTQQSLAEKEAHLANLRIERRKQLEEILEM-KQEALLAAISEKDANIALLELSASKKKKTQEE 898
Cdd:pfam17380 441 EEERAReMERVRLEEQERQQQVERLRQQEEERKRKKLELeKEKRDRKRAEEQRRKILEKELEERKQAMIEEE 512
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
586-909 |
3.78e-03 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 41.42 E-value: 3.78e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 586 LEEALSEKE---RIIERLKEQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEhasslasaglkrds 662
Cdd:pfam07888 36 LEECLQERAellQAQEAANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSREKHEELEE-------------- 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 663 KLKSLEIAIEQKKEECSKLEAQlKKQAEQLFNQMynpahnvEDDSRMNPEfadriKQLDKEAsyyrdECGKAQAEVDRLL 742
Cdd:pfam07888 102 KYKELSASSEELSEEKDALLAQ-RAAHEARIREL-------EEDIKTLTQ-----RVLERET-----ELERMKERAKKAG 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 743 EILKEVENEKNDKDKKIAELESlTLRHMkdqNKKVANLKHNQQLEKKKNAQLLEEVRRREDSMADNSQHLQieelmnALE 822
Cdd:pfam07888 164 AQRKEEEAERKQLQAKLQQTEE-ELRSL---SKEFQELRNSLAQRDTQVLQLQDTITTLTQKLTTAHRKEA------ENE 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 823 KTRQELDATKARLASTQQSLAEKEAHLANLRIERRKQLEEILEMKQEALLAAISEKDANIALLELSASKKKKTQEEVMAL 902
Cdd:pfam07888 234 ALLEELRSLQERLNASERKVEGLGEELSSMAAQRDRTQAELHQARLQAAQLTLQLADASLALREGRARWAQERETLQQSA 313
|
....*..
gi 1570463013 903 KREKDRL 909
Cdd:pfam07888 314 EADKDRI 320
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
804-924 |
4.07e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 40.90 E-value: 4.07e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 804 SMADNSQHLQIEELMNALEKTRQELDATKARLASTQQSLAEKEAHLANL--RIERRKQLEEILEMKQEALLAAISEKDAN 881
Cdd:COG4942 12 ALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALerRIAALARRIRALEQELAALEAELAELEKE 91
|
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 1570463013 882 IALLElsasKKKKTQEEVMAlkrekDRLVHQLKQQTQNRMKLM 924
Cdd:COG4942 92 IAELR----AELEAQKEELA-----ELLRALYRLGRQPPLALL 125
|
|
| MPS2 |
pfam17060 |
Monopolar spindle protein 2; Is a fungal transmembrane protein which is part of the component ... |
472-607 |
4.12e-03 |
|
Monopolar spindle protein 2; Is a fungal transmembrane protein which is part of the component of the spindle pole body (SPB) required for the insertion of the nascent SPB into the nuclear envelope and for the proper execution of spindle pole body (SPB) duplication. It seems that Mps2-Spc24 interaction may contribute to the localization of Spc24 and other kinetochore components to the inner plaque of the SPB.
Pssm-ID: 407228 [Multi-domain] Cd Length: 340 Bit Score: 40.73 E-value: 4.12e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 472 EVLKESLTAKEQRAAILQTEVDALRLRLEEKES------FLNKKTKQLQDLTEekgTLAGEIRDMKDMLEVKERKINVLQ 545
Cdd:pfam17060 105 ELKEDVKSSPRSEADSLGTPIKVDLLRNLKPQEspetprRINRKYKSLELRVE---SMKDELEFKDETIMEKDRELTELT 181
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1570463013 546 KKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDT----ALATLEEALSEKERIIERLKEQRERD 607
Cdd:pfam17060 182 STISKLKDKYDFLSREFEFYKQHHEHGGNNSIKTATkhefIISELKRKLQEQNRLIRILQEQIQFD 247
|
|
| ClyA_Cry6Aa-like |
cd22656 |
Bacillus thuringiensis crystal 6Aa (Cry6Aa) toxin, and similar proteins; This model includes ... |
514-653 |
4.70e-03 |
|
Bacillus thuringiensis crystal 6Aa (Cry6Aa) toxin, and similar proteins; This model includes pesticidal Cry6Aa toxin from Bacillus thuringiensis, one of the many parasporal crystal (Cry) toxins produced during the sporulation phase of growth. Many of these proteins are toxic to numerous insect species and have been effectively used as proteinaceous insecticides to directly kill insect pests; some have been used to control insect growth on transgenic agricultural plants. Cry6Aa exists as a protoxin, which is activated by cleavage using trypsin. Structure studies for Cry6Aa support a mechanism of action by pore formation, similar to cytolysin A (ClyA)-type alpha pore-forming toxins (alpha-PFTs) such as HblB, and bioassay and mutation studies show that Cry6Aa is an active pore-forming toxin. Cry6Aa shows atypical features compared to other members of alpha-PFTs, including internal repeat sequences and small loop regions within major alpha helices.
Pssm-ID: 439154 [Multi-domain] Cd Length: 309 Bit Score: 40.43 E-value: 4.70e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 514 QDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNtdtalatlEEALSEK 593
Cdd:cd22656 110 EELEEAKKTIKALLDDLLKEAKKYQDKAAKVVDKLTDFENQTEKDQTALETLEKALKDLLTDEGG--------AIARKEI 181
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 594 ERIIERLKEQRErddrerlEEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSL 653
Cdd:cd22656 182 KDLQKELEKLNE-------EYAAKLKAKIDELKALIADDEAKLAAALRLIADLTAADTDL 234
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
265-406 |
5.20e-03 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 40.58 E-value: 5.20e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 265 RLQAEHDRQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKG---------LPSKSLEDDNER------- 328
Cdd:COG3883 48 ELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALYRSGgsvsyldvlLGSESFSDFLDRlsalski 127
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1570463013 329 TRRMAEAESQVSHLEVILDQKEKENIHLREELHR-RSQLQpepAKTKALQTVIEMKDTKIASLERNIRDLEDEIQMLKA 406
Cdd:COG3883 128 ADADADLLEELKADKAELEAKKAELEAKLAELEAlKAELE---AAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEA 203
|
|
| XRN1 |
COG5049 |
5'-3' exonuclease [Replication, recombination and repair]; |
238-440 |
5.60e-03 |
|
5'-3' exonuclease [Replication, recombination and repair];
Pssm-ID: 227382 [Multi-domain] Cd Length: 953 Bit Score: 41.06 E-value: 5.60e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 238 LNHLLQQESGNRGAEHFTIELTEENFRRLQAEHDRQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGL 317
Cdd:COG5049 366 LAILGSFEDDIFKKDHIQEERKNESLERFSLRKERKEGLKGMPRVVYEQKKLIGSIKPTLMDQLQEKKSPDLPDEEFIDT 445
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 318 PSKSLEDDNERTRRMAEAESQVSHLEVILDQKEKENIHLREELHRRSQLQPEPAKTKALQTVIEMKDTKIASlernirDL 397
Cdd:COG5049 446 LALPKDLDMKNHELFLKRFANDLGLSISKAIKSKGNYSLEMDIASDSPDEDEEEFESEVDSIRKIPDKYVNI------IV 519
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 1570463013 398 EDEIQmlkaNGVLNTEDREEEIKQIEVYKSHSKFMKTKIDQLK 440
Cdd:COG5049 520 EEEEE----NETEKTVNLRFPGWKERYYTSKLHFTTDSEEKIR 558
|
|
| hsdR |
PRK11448 |
type I restriction enzyme EcoKI subunit R; Provisional |
544-663 |
5.64e-03 |
|
type I restriction enzyme EcoKI subunit R; Provisional
Pssm-ID: 236912 [Multi-domain] Cd Length: 1123 Bit Score: 41.09 E-value: 5.64e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 544 LQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRERLEEiesFRKENK 623
Cdd:PRK11448 147 LQQEVLTLKQQLELQAREKAQSQALAEAQQQELVALEGLAAELEEKQQELEAQLEQLQEKAAETSQERKQK---RKEITD 223
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 1570463013 624 DLKEKVnalqaELTEKES-SLIDlkehaSSLASAGLKRDSK 663
Cdd:PRK11448 224 QAAKRL-----ELSEEETrILID-----QQLRKAGWEADSK 254
|
|
| PRK12705 |
PRK12705 |
hypothetical protein; Provisional |
484-655 |
5.71e-03 |
|
hypothetical protein; Provisional
Pssm-ID: 237178 [Multi-domain] Cd Length: 508 Bit Score: 40.85 E-value: 5.71e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 484 RAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRdmkdmlevkerkinvlqkKIENLQEQLRDKDKQLT 563
Cdd:PRK12705 40 QEAQKEAEEKLEAALLEAKELLLRERNQQRQEARREREELQREEE------------------RLVQKEEQLDARAEKLD 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 564 NLKDRvkslqtdssntdtaLATLEEALSEKERIIERLKEQRErddrERLEEIESFRKENKdLKEKVNALQAELTEKESSL 643
Cdd:PRK12705 102 NLENQ--------------LEEREKALSARELELEELEKQLD----NELYRVAGLTPEQA-RKLLLKLLDAELEEEKAQR 162
|
170
....*....|..
gi 1570463013 644 IDLKEHASSLAS 655
Cdd:PRK12705 163 VKKIEEEADLEA 174
|
|
| DUF4795 |
pfam16043 |
Domain of unknown function (DUF4795); This family of proteins is functionally uncharacterized. ... |
436-571 |
5.75e-03 |
|
Domain of unknown function (DUF4795); This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and eukaryotes. Proteins in this family are typically between 285 and 978 amino acids in length.
Pssm-ID: 464990 [Multi-domain] Cd Length: 181 Bit Score: 39.21 E-value: 5.75e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 436 IDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRleEKESFLNKKTkQLQD 515
Cdd:pfam16043 9 LDQLQALILDLQEELEKLSETTSELSERLQQRQKHLEALYQQIEKLEKVKADKEVVEEELDEK--ADKEALASKV-SRDQ 85
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 1570463013 516 LTEEKGTLAGEIRDMKDMLEVKERKinvLQKKIENLQEQLRDKD--KQLTNLKDRVKS 571
Cdd:pfam16043 86 FDETLEELNQMLQELLDKLEGQEDA---WKKALETLSEELDTKLdrLELDPLKELLER 140
|
|
| COG1340 |
COG1340 |
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]; |
540-871 |
6.48e-03 |
|
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
Pssm-ID: 440951 [Multi-domain] Cd Length: 297 Bit Score: 39.89 E-value: 6.48e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 540 KINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSntdtALATLEEALSEKER-IIERLKEQRERDDrERLEEIESF 618
Cdd:COG1340 2 KTDELSSSLEELEEKIEELREEIEELKEKRDELNEELK----ELAEKRDELNAQVKeLREEAQELREKRD-ELNEKVKEL 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 619 RKENKDLKEKVNALQAELTEKESSLidlkehasslasaglkrdsklksleiaieQKKEECSKLEAQLKKQAEQLFNQMYN 698
Cdd:COG1340 77 KEERDELNEKLNELREELDELRKEL-----------------------------AELNKAGGSIDKLRKEIERLEWRQQT 127
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 699 PAHNVEDDSrmnpEFADRIKQLDKEasyyrdecgkaqaevdrlLEILKEVENEKNDKDKKIAELESLTLRhMKDQNKKVA 778
Cdd:COG1340 128 EVLSPEEEK----ELVEKIKELEKE------------------LEKAKKALEKNEKLKELRAELKELRKE-AEEIHKKIK 184
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 779 NL------KHNQQLEKKKNAqllEEVRRREDSMadnsqHLQIEELMNALEKTRQELDATKARLASTQQSLAEKEAHLANL 852
Cdd:COG1340 185 ELaeeaqeLHEEMIELYKEA---DELRKEADEL-----HKEIVEAQEKADELHEEIIELQKELRELRKELKKLRKKQRAL 256
|
330
....*....|....*....
gi 1570463013 853 RieRRKQLEEILEMKQEAL 871
Cdd:COG1340 257 K--REKEKEELEEKAEEIF 273
|
|
| PRK12705 |
PRK12705 |
hypothetical protein; Provisional |
450-612 |
7.13e-03 |
|
hypothetical protein; Provisional
Pssm-ID: 237178 [Multi-domain] Cd Length: 508 Bit Score: 40.46 E-value: 7.13e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 450 LLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKEsfLNKKTKQLQDLTEEKGTLAGEIRD 529
Cdd:PRK12705 25 LKKRQRLAKEAERILQEAQKEAEEKLEAALLEAKELLLRERNQQRQEARREREE--LQREEERLVQKEEQLDARAEKLDN 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 530 MKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLkdrvkslqTDSSNTDTALATLEEALSEKERIIERLKEQRERDDR 609
Cdd:PRK12705 103 LENQLEEREKALSARELELEELEKQLDNELYRVAGL--------TPEQARKLLLKLLDAELEEEKAQRVKKIEEEADLEA 174
|
...
gi 1570463013 610 ERL 612
Cdd:PRK12705 175 ERK 177
|
|
| CDC3 |
COG5019 |
Septin family protein [Cell cycle control, cell division, chromosome partitioning, ... |
568-651 |
7.14e-03 |
|
Septin family protein [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton];
Pssm-ID: 227352 [Multi-domain] Cd Length: 373 Bit Score: 40.00 E-value: 7.14e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 568 RVKSLQTDSSNTDTALATL-EEALSEKERIIERLKEQRERDDRERLEEIESF-RKENKDLKEKVNALQAELTEKESSLID 645
Cdd:COG5019 288 RTEKLSGLKNSGEPSLKEIhEARLNEEERELKKKFTEKIREKEKRLEELEQNlIEERKELNSKLEEIQKKLEDLEKRLEK 367
|
....*.
gi 1570463013 646 LKEHAS 651
Cdd:COG5019 368 LKSNKS 373
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
153-381 |
7.70e-03 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 40.49 E-value: 7.70e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 153 QLKELQRENDLLRKEldikdsKLGSSMNSIKTFWSPEL----KKERVLRKEEAARMSVLKEQMRVSHEENQHLQLTIQAL 228
Cdd:pfam17380 354 RQEERKRELERIRQE------EIAMEISRMRELERLQMerqqKNERVRQELEAARKVKILEEERQRKIQQQKVEMEQIRA 427
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 229 QDELRTQRDLNHLlqQESGNRGAEHFTIELTE--ENFRRL-QAEHDRQAKELFLLRKTLEEMELRIETQKQTLNARDESI 305
Cdd:pfam17380 428 EQEEARQREVRRL--EEERAREMERVRLEEQErqQQVERLrQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEERK 505
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 306 KKLLEMLQSKGLPSKSLEDDN-----ERTRRMAEAESQVshlEVILDQKEKENIHLREELHRRSQLQPEPAKTKALQTVI 380
Cdd:pfam17380 506 QAMIEEERKRKLLEKEMEERQkaiyeEERRREAEEERRK---QQEMEERRRIQEQMRKATEERSRLEAMEREREMMRQIV 582
|
.
gi 1570463013 381 E 381
Cdd:pfam17380 583 E 583
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
793-925 |
8.78e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 40.28 E-value: 8.78e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 793 QLLEEVRRREDSMAdnsqhlQIEELMNALEKTRQELDATKARLASTQQSLAEKEAHLANLRIERRKqlEEILEMKQEALL 872
Cdd:COG4913 242 EALEDAREQIELLE------PIRELAERYAAARERLAELEYLRAALRLWFAQRRLELLEAELEELR--AELARLEAELER 313
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 1570463013 873 AAISEKDANIALLELSASKKKKTQEEVMALKREKDRLVHQLKQQTQNRMKLMA 925
Cdd:COG4913 314 LEARLDALREELDELEAQIRGNGGDRLEQLEREIERLERELEERERRRARLEA 366
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
356-692 |
9.62e-03 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 39.88 E-value: 9.62e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 356 LREELHRRSQL-QPEPAKTKALQTVIEMKDTKIASLERNIRDLEDEIQMLKANGVLNTEDREEEIKQIEVYKSHSKFMKT 434
Cdd:pfam07888 36 LEECLQERAELlQAQEAANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSREKHEELEEKYKELSASSEELSE 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 435 KIDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQ 514
Cdd:pfam07888 116 EKDALLAQRAAHEARIRELEEDIKTLTQRVLERETELERMKERAKKAGAQRKEEEAERKQLQAKLQQTEEELRSLSKEFQ 195
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 515 DLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKI---ENLQEQLRDKDKQLTNLKDRVKSLQTDSSNT----DTALATLE 587
Cdd:pfam07888 196 ELRNSLAQRDTQVLQLQDTITTLTQKLTTAHRKEaenEALLEELRSLQERLNASERKVEGLGEELSSMaaqrDRTQAELH 275
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570463013 588 EALSEKERIIERLKEQR--ERDDRERL-EEIESFRKENKDLKEKVNALQAELTEKESSLIDLK-EHASSLASAGLKRDSK 663
Cdd:pfam07888 276 QARLQAAQLTLQLADASlaLREGRARWaQERETLQQSAEADKDRIEKLSAELQRLEERLQEERmEREKLEVELGREKDCN 355
|
330 340
....*....|....*....|....*....
gi 1570463013 664 LKSLEIAIEQKKEECSKLEAqLKKQAEQL 692
Cdd:pfam07888 356 RVQLSESRRELQELKASLRV-AQKEKEQL 383
|
|
| |
