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Conserved domains on  [gi|1561942250|ref|XP_027705202|]
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coiled-coil domain-containing protein 82 [Vombatus ursinus]

Protein Classification

DUF4211 domain-containing protein( domain architecture ID 10341225)

DUF4211 domain-containing protein similar to Homo sapiens proline-rich protein 12 and Xenopus laevis glutamine and serine-rich protein 1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DUF4211 pfam13926
Domain of unknown function (DUF4211);
275-423 1.67e-41

Domain of unknown function (DUF4211);


:

Pssm-ID: 464045  Cd Length: 138  Bit Score: 145.48  E-value: 1.67e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561942250 275 FVVQDEEENqnqsgekMTASQLQLVKRNSLYSFSDHYTHFERVVKAFLINALDDTFLGTLYDgtrqkSYAQDMLTSLHYL 354
Cdd:pfam13926   2 FIVEDDDDE-------LGVPDEELPLEFSRLSHQDLKEHFKVVVEWLVHNAIDPDFLRSLYD-----KDDEYYLVALRKL 69

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561942250 355 DGRfVQPRLENLVSRSRWKEQYKERVENYPNVSIRWRTPENCSCQACGLHRY-CKYTVHLSGKLYNDRTM 423
Cdd:pfam13926  70 DDE-VQGLADSLLSSSAWKPEFKKALEARPELRITELDPKDGGCDACNRSNHpATFTIRLSGKPYNKETL 138
DUF4196 super family cl16435
Domain of unknown function (DUF4196); This is a short region of ccdc82_homologs that is ...
 100-214 5.00e-17

Domain of unknown function (DUF4196); This is a short region of ccdc82_homologs that is conserved from Schizo. pombe up to humans. The function is not known.


The actual alignment was detected with superfamily member pfam13846:

Pssm-ID: 433523  Cd Length: 112  Bit Score: 76.78  E-value: 5.00e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561942250 100 KSGGLSDHEEEKKENKCKTIN-TDYEKDLSQEHTDSKQQSDQIVteEDVEEEEHITRGKRKRVSSVMYDSDDSDDSDILV 178
Cdd:pfam13846   1 NTGNSSTYEEEKNKTKHRSIDlPDDEKHLSQEENDLNKHTGQII--EEDLEEEHIKRGKRKRISSVMYDSDDSDDSDILV 78

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 1561942250 179 RRVDVKRRRIVEDDDCSSVEVDQKPPksEKSSAIRK 214
Cdd:pfam13846  79 RKVGVKRPRRVVEDECSSVEMEQKNP--EKTSAARK 112
MSCRAMM_ClfA super family cl41352
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 39-139 1.09e-06

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


The actual alignment was detected with superfamily member NF033609:

Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 51.45  E-value: 1.09e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561942250  39 DSDEELDSDEELDSDESVDSDESHDSDESHDSDESIDSNKKLD-------DKELDLTNKAENNKEHITKSGGLSDHEEEK 111
Cdd:NF033609  703 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDsdsdsdsDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 782

                          90       100
                  ....*....|....*....|....*...
gi 1561942250 112 KENKCKTINTDYEKDlSQEHTDSKQQSD 139
Cdd:NF033609  783 DSDSDSDSDSDSDSD-SDSDSDSDSDSD 809
 
Name Accession Description Interval E-value
DUF4211 pfam13926
Domain of unknown function (DUF4211);
275-423 1.67e-41

Domain of unknown function (DUF4211);


Pssm-ID: 464045  Cd Length: 138  Bit Score: 145.48  E-value: 1.67e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561942250 275 FVVQDEEENqnqsgekMTASQLQLVKRNSLYSFSDHYTHFERVVKAFLINALDDTFLGTLYDgtrqkSYAQDMLTSLHYL 354
Cdd:pfam13926   2 FIVEDDDDE-------LGVPDEELPLEFSRLSHQDLKEHFKVVVEWLVHNAIDPDFLRSLYD-----KDDEYYLVALRKL 69

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561942250 355 DGRfVQPRLENLVSRSRWKEQYKERVENYPNVSIRWRTPENCSCQACGLHRY-CKYTVHLSGKLYNDRTM 423
Cdd:pfam13926  70 DDE-VQGLADSLLSSSAWKPEFKKALEARPELRITELDPKDGGCDACNRSNHpATFTIRLSGKPYNKETL 138
DUF4196 pfam13846
Domain of unknown function (DUF4196); This is a short region of ccdc82_homologs that is ...
 100-214 5.00e-17

Domain of unknown function (DUF4196); This is a short region of ccdc82_homologs that is conserved from Schizo. pombe up to humans. The function is not known.


Pssm-ID: 433523  Cd Length: 112  Bit Score: 76.78  E-value: 5.00e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561942250 100 KSGGLSDHEEEKKENKCKTIN-TDYEKDLSQEHTDSKQQSDQIVteEDVEEEEHITRGKRKRVSSVMYDSDDSDDSDILV 178
Cdd:pfam13846   1 NTGNSSTYEEEKNKTKHRSIDlPDDEKHLSQEENDLNKHTGQII--EEDLEEEHIKRGKRKRISSVMYDSDDSDDSDILV 78

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 1561942250 179 RRVDVKRRRIVEDDDCSSVEVDQKPPksEKSSAIRK 214
Cdd:pfam13846  79 RKVGVKRPRRVVEDECSSVEMEQKNP--EKTSAARK 112
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 39-139 1.09e-06

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 51.45  E-value: 1.09e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561942250  39 DSDEELDSDEELDSDESVDSDESHDSDESHDSDESIDSNKKLD-------DKELDLTNKAENNKEHITKSGGLSDHEEEK 111
Cdd:NF033609  703 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDsdsdsdsDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 782

                          90       100
                  ....*....|....*....|....*...
gi 1561942250 112 KENKCKTINTDYEKDlSQEHTDSKQQSD 139
Cdd:NF033609  783 DSDSDSDSDSDSDSD-SDSDSDSDSDSD 809
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 39-139 1.40e-06

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 51.06  E-value: 1.40e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561942250  39 DSDEELDSDEELDSDESVDSDESHDSDESHDSDESIDSNKKLD-DKELDLTNKAENNKEHITKSGGLSDHEEEKKENKCK 117
Cdd:NF033609  697 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDsDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 776

                          90       100
                  ....*....|....*....|..
gi 1561942250 118 TINTDYEKDlSQEHTDSKQQSD 139
Cdd:NF033609  777 DSDSDSDSD-SDSDSDSDSDSD 797
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 39-139 4.51e-06

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 49.52  E-value: 4.51e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561942250  39 DSDEELDSDEELDSDESVDSDESHDSDESHDSDESIDSNKKLD-DKELDLTNKAENNKEHITKSGGLSDHEEEKKENKCK 117
Cdd:NF033609  597 DSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDsDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 676

                          90       100
                  ....*....|....*....|..
gi 1561942250 118 TINTDYEKDlSQEHTDSKQQSD 139
Cdd:NF033609  677 DSDSDSDSD-SDSDSDSDSDSD 697
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 39-209 5.93e-06

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 49.14  E-value: 5.93e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561942250  39 DSDEELDSDEELDSDESVDSDESHDSDESHDSDESIDSNKKLD-DKELDLTNKAENNKEHITKSGGLSDHEEEKKENKCK 117
Cdd:NF033609  709 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDsDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 788

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561942250 118 TINTDYEKDL-SQEHTDSKQQSDQIVTEEDVEEEEHITRGKRKRVSSVMYDSDDSDDSDILVRRVDVKRRRIVEDDDCSS 196
Cdd:NF033609  789 DSDSDSDSDSdSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSESDSNSDSESGS 868

                         170
                  ....*....|...
gi 1561942250 197 VEvDQKPPKSEKS 209
Cdd:NF033609  869 NN-NVVPPNSPKN 880
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 39-139 6.69e-06

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 49.14  E-value: 6.69e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561942250  39 DSDEELDSDEELDSDESVDSDESHDSDESHDSDESIDSNKKLD-DKELDLTNKAENNKEHITKSGGLSDHEEEKKENKCK 117
Cdd:NF033609  591 GSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDsDSASDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 670

                          90       100
                  ....*....|....*....|...
gi 1561942250 118 TINTDYEKDL-SQEHTDSKQQSD 139
Cdd:NF033609  671 DSDSDSDSDSdSDSDSDSDSDSD 693
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 39-139 1.54e-05

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 47.98  E-value: 1.54e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561942250  39 DSDEELDSDEELDSDESVDSDESHDSDESHDSDESIDSNKKLD-DKELDLTNKAENNKEHITKSGGLSDHEEEKKENKCK 117
Cdd:NF033609  585 DSTSDSGSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDsDSASDSDSASDSDSDSDSDSDSDSDSDSDSDSDSDS 664

                          90       100
                  ....*....|....*....|..
gi 1561942250 118 TINTDYEKDlSQEHTDSKQQSD 139
Cdd:NF033609  665 DSDSDSDSD-SDSDSDSDSDSD 685
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 39-139 2.62e-05

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 47.21  E-value: 2.62e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561942250  39 DSDEELDSDEELDSDESVDSDESHDSDESHDSDESIDSNKKLD-DKELDLTNKAENNKEHITKSGGLSDHEEEKKENKCK 117
Cdd:NF033609  579 GSDSGSDSTSDSGSDSASDSDSASDSDSASDSDSASDSDSASDsDSASDSDSASDSDSASDSDSDSDSDSDSDSDSDSDS 658

                          90       100
                  ....*....|....*....|..
gi 1561942250 118 TINTDYEKDlSQEHTDSKQQSD 139
Cdd:NF033609  659 DSDSDSDSD-SDSDSDSDSDSD 679
DNA_pol_phi pfam04931
DNA polymerase phi; This family includes the fifth essential DNA polymerase in yeast EC:2.7.7. ...
 39-83 1.04e-04

DNA polymerase phi; This family includes the fifth essential DNA polymerase in yeast EC:2.7.7.7. Pol5p is localized exclusively to the nucleolus and binds near or at the enhancer region of rRNA-encoding DNA repeating units.


Pssm-ID: 461488  Cd Length: 765  Bit Score: 44.92  E-value: 1.04e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 1561942250  39 DSDEELDSDEELDSDESVDSDESHDSDESHDS-DESIDSNKKLDDK 83
Cdd:pfam04931 645 DDDEEEDDDDEDDEDSEEDDDEDDDDEDEEDDdDEDVDEIDELRAK 690
PTZ00007 PTZ00007
(NAP-L) nucleosome assembly protein -L; Provisional
 39-99 3.45e-03

(NAP-L) nucleosome assembly protein -L; Provisional


Pssm-ID: 240226 [Multi-domain]  Cd Length: 337  Bit Score: 39.78  E-value: 3.45e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1561942250  39 DSDEELDSDEELDSDESVDSDESHDSDESHDSDESIDsnkklDDKELDLTNKAENNKEHIT 99
Cdd:PTZ00007  281 DEDSDYSSDEDDDDYDSYDSSDSASSDSNSDVDTNEE-----DDRGEKESNGAKSNELHLT 336
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 39-285 7.44e-03

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 39.12  E-value: 7.44e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561942250  39 DSDEELDSDEELDSDESVDSDESHDSDESHDSDESIDSNKKLD-DKELDLTNKAENNKEHITKSGGLSDHEEEKKENKCK 117
Cdd:NF033609  621 DSDSASDSDSASDSDSASDSDSDSDSDSDSDSDSDSDSDSDSDsDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 700

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561942250 118 TINTDYEKDL-SQEHTDSKQQSDQIVTEEDVEEEEHITRGKRKRVSSVMYDSDDSDDSDILVRRVDVKRRRIVEDDDCSS 196
Cdd:NF033609  701 DSDSDSDSDSdSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 780

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561942250 197 -VEVDQKPPKSEKSSAIRKQEQLQKLKELSKQRSRQRRNSGRDFE-DSEEESLPDSDLDDDEDDDEDDDDEEGDDYIIDG 274
Cdd:NF033609  781 dSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDsDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSESDS 860

                         250
                  ....*....|.
gi 1561942250 275 FVVQDEEENQN 285
Cdd:NF033609  861 NSDSESGSNNN 871
 
Name Accession Description Interval E-value
DUF4211 pfam13926
Domain of unknown function (DUF4211);
275-423 1.67e-41

Domain of unknown function (DUF4211);


Pssm-ID: 464045  Cd Length: 138  Bit Score: 145.48  E-value: 1.67e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561942250 275 FVVQDEEENqnqsgekMTASQLQLVKRNSLYSFSDHYTHFERVVKAFLINALDDTFLGTLYDgtrqkSYAQDMLTSLHYL 354
Cdd:pfam13926   2 FIVEDDDDE-------LGVPDEELPLEFSRLSHQDLKEHFKVVVEWLVHNAIDPDFLRSLYD-----KDDEYYLVALRKL 69

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561942250 355 DGRfVQPRLENLVSRSRWKEQYKERVENYPNVSIRWRTPENCSCQACGLHRY-CKYTVHLSGKLYNDRTM 423
Cdd:pfam13926  70 DDE-VQGLADSLLSSSAWKPEFKKALEARPELRITELDPKDGGCDACNRSNHpATFTIRLSGKPYNKETL 138
DUF4196 pfam13846
Domain of unknown function (DUF4196); This is a short region of ccdc82_homologs that is ...
 100-214 5.00e-17

Domain of unknown function (DUF4196); This is a short region of ccdc82_homologs that is conserved from Schizo. pombe up to humans. The function is not known.


Pssm-ID: 433523  Cd Length: 112  Bit Score: 76.78  E-value: 5.00e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561942250 100 KSGGLSDHEEEKKENKCKTIN-TDYEKDLSQEHTDSKQQSDQIVteEDVEEEEHITRGKRKRVSSVMYDSDDSDDSDILV 178
Cdd:pfam13846   1 NTGNSSTYEEEKNKTKHRSIDlPDDEKHLSQEENDLNKHTGQII--EEDLEEEHIKRGKRKRISSVMYDSDDSDDSDILV 78

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 1561942250 179 RRVDVKRRRIVEDDDCSSVEVDQKPPksEKSSAIRK 214
Cdd:pfam13846  79 RKVGVKRPRRVVEDECSSVEMEQKNP--EKTSAARK 112
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 39-139 1.09e-06

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 51.45  E-value: 1.09e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561942250  39 DSDEELDSDEELDSDESVDSDESHDSDESHDSDESIDSNKKLD-------DKELDLTNKAENNKEHITKSGGLSDHEEEK 111
Cdd:NF033609  703 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDsdsdsdsDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 782

                          90       100
                  ....*....|....*....|....*...
gi 1561942250 112 KENKCKTINTDYEKDlSQEHTDSKQQSD 139
Cdd:NF033609  783 DSDSDSDSDSDSDSD-SDSDSDSDSDSD 809
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 39-139 1.40e-06

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 51.06  E-value: 1.40e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561942250  39 DSDEELDSDEELDSDESVDSDESHDSDESHDSDESIDSNKKLD-DKELDLTNKAENNKEHITKSGGLSDHEEEKKENKCK 117
Cdd:NF033609  697 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDsDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 776

                          90       100
                  ....*....|....*....|..
gi 1561942250 118 TINTDYEKDlSQEHTDSKQQSD 139
Cdd:NF033609  777 DSDSDSDSD-SDSDSDSDSDSD 797
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 39-139 4.51e-06

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 49.52  E-value: 4.51e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561942250  39 DSDEELDSDEELDSDESVDSDESHDSDESHDSDESIDSNKKLD-DKELDLTNKAENNKEHITKSGGLSDHEEEKKENKCK 117
Cdd:NF033609  597 DSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDsDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 676

                          90       100
                  ....*....|....*....|..
gi 1561942250 118 TINTDYEKDlSQEHTDSKQQSD 139
Cdd:NF033609  677 DSDSDSDSD-SDSDSDSDSDSD 697
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 39-209 5.93e-06

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 49.14  E-value: 5.93e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561942250  39 DSDEELDSDEELDSDESVDSDESHDSDESHDSDESIDSNKKLD-DKELDLTNKAENNKEHITKSGGLSDHEEEKKENKCK 117
Cdd:NF033609  709 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDsDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 788

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561942250 118 TINTDYEKDL-SQEHTDSKQQSDQIVTEEDVEEEEHITRGKRKRVSSVMYDSDDSDDSDILVRRVDVKRRRIVEDDDCSS 196
Cdd:NF033609  789 DSDSDSDSDSdSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSESDSNSDSESGS 868

                         170
                  ....*....|...
gi 1561942250 197 VEvDQKPPKSEKS 209
Cdd:NF033609  869 NN-NVVPPNSPKN 880
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 39-139 6.69e-06

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 49.14  E-value: 6.69e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561942250  39 DSDEELDSDEELDSDESVDSDESHDSDESHDSDESIDSNKKLD-DKELDLTNKAENNKEHITKSGGLSDHEEEKKENKCK 117
Cdd:NF033609  591 GSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDsDSASDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 670

                          90       100
                  ....*....|....*....|...
gi 1561942250 118 TINTDYEKDL-SQEHTDSKQQSD 139
Cdd:NF033609  671 DSDSDSDSDSdSDSDSDSDSDSD 693
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 39-139 1.54e-05

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 47.98  E-value: 1.54e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561942250  39 DSDEELDSDEELDSDESVDSDESHDSDESHDSDESIDSNKKLD-DKELDLTNKAENNKEHITKSGGLSDHEEEKKENKCK 117
Cdd:NF033609  585 DSTSDSGSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDsDSASDSDSASDSDSDSDSDSDSDSDSDSDSDSDSDS 664

                          90       100
                  ....*....|....*....|..
gi 1561942250 118 TINTDYEKDlSQEHTDSKQQSD 139
Cdd:NF033609  665 DSDSDSDSD-SDSDSDSDSDSD 685
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 39-139 2.62e-05

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 47.21  E-value: 2.62e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561942250  39 DSDEELDSDEELDSDESVDSDESHDSDESHDSDESIDSNKKLD-DKELDLTNKAENNKEHITKSGGLSDHEEEKKENKCK 117
Cdd:NF033609  579 GSDSGSDSTSDSGSDSASDSDSASDSDSASDSDSASDSDSASDsDSASDSDSASDSDSASDSDSDSDSDSDSDSDSDSDS 658

                          90       100
                  ....*....|....*....|..
gi 1561942250 118 TINTDYEKDlSQEHTDSKQQSD 139
Cdd:NF033609  659 DSDSDSDSD-SDSDSDSDSDSD 679
DNA_pol_phi pfam04931
DNA polymerase phi; This family includes the fifth essential DNA polymerase in yeast EC:2.7.7. ...
 39-83 1.04e-04

DNA polymerase phi; This family includes the fifth essential DNA polymerase in yeast EC:2.7.7.7. Pol5p is localized exclusively to the nucleolus and binds near or at the enhancer region of rRNA-encoding DNA repeating units.


Pssm-ID: 461488  Cd Length: 765  Bit Score: 44.92  E-value: 1.04e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 1561942250  39 DSDEELDSDEELDSDESVDSDESHDSDESHDS-DESIDSNKKLDDK 83
Cdd:pfam04931 645 DDDEEEDDDDEDDEDSEEDDDEDDDDEDEEDDdDEDVDEIDELRAK 690
PTZ00007 PTZ00007
(NAP-L) nucleosome assembly protein -L; Provisional
 39-99 3.45e-03

(NAP-L) nucleosome assembly protein -L; Provisional


Pssm-ID: 240226 [Multi-domain]  Cd Length: 337  Bit Score: 39.78  E-value: 3.45e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1561942250  39 DSDEELDSDEELDSDESVDSDESHDSDESHDSDESIDsnkklDDKELDLTNKAENNKEHIT 99
Cdd:PTZ00007  281 DEDSDYSSDEDDDDYDSYDSSDSASSDSNSDVDTNEE-----DDRGEKESNGAKSNELHLT 336
DNA_pol_phi pfam04931
DNA polymerase phi; This family includes the fifth essential DNA polymerase in yeast EC:2.7.7. ...
 39-93 3.67e-03

DNA polymerase phi; This family includes the fifth essential DNA polymerase in yeast EC:2.7.7.7. Pol5p is localized exclusively to the nucleolus and binds near or at the enhancer region of rRNA-encoding DNA repeating units.


Pssm-ID: 461488  Cd Length: 765  Bit Score: 39.91  E-value: 3.67e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1561942250  39 DSDEELDSDEELDSDESVDSDESHDSDESHDSDESIDSNKKLDDKELDLTNKAEN 93
Cdd:pfam04931 639 EDEDEEDDDEEEDDDDEDDEDSEEDDDEDDDDEDEEDDDDEDVDEIDELRAKLAE 693
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 39-285 7.44e-03

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 39.12  E-value: 7.44e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561942250  39 DSDEELDSDEELDSDESVDSDESHDSDESHDSDESIDSNKKLD-DKELDLTNKAENNKEHITKSGGLSDHEEEKKENKCK 117
Cdd:NF033609  621 DSDSASDSDSASDSDSASDSDSDSDSDSDSDSDSDSDSDSDSDsDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 700

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561942250 118 TINTDYEKDL-SQEHTDSKQQSDQIVTEEDVEEEEHITRGKRKRVSSVMYDSDDSDDSDILVRRVDVKRRRIVEDDDCSS 196
Cdd:NF033609  701 DSDSDSDSDSdSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 780

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561942250 197 -VEVDQKPPKSEKSSAIRKQEQLQKLKELSKQRSRQRRNSGRDFE-DSEEESLPDSDLDDDEDDDEDDDDEEGDDYIIDG 274
Cdd:NF033609  781 dSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDsDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSESDS 860

                         250
                  ....*....|.
gi 1561942250 275 FVVQDEEENQN 285
Cdd:NF033609  861 NSDSESGSNNN 871
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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