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Conserved domains on  [gi|1370510869|ref|XP_024302671|]
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radial spoke head 10 homolog B2 isoform X2 [Homo sapiens]

Protein Classification

MORN repeat-containing protein( domain architecture ID 11468649)

membrane-occupation-and-recognition-nexus (MORN) repeat-containing protein may be involved in protein-protein interactions

PubMed:  33296386|35568981

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
COG4642 COG4642
Uncharacterized conserved protein [Function unknown];
86-336 7.76e-44

Uncharacterized conserved protein [Function unknown];


:

Pssm-ID: 443680 [Multi-domain]  Cd Length: 271  Bit Score: 160.12  E-value: 7.76e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370510869  86 YEGEKVRGLYEGEGFAAFQGGCTYRGMFSEGLMHGQGTYIWADGLKYEGDFVKNVPMNHGVYTWPDGSMYEGEVVNGMRN 165
Cdd:COG4642    81 GGGGKGDGGDGGGGEGGFGGGGGGGGGKKGGGGGGGGVLEGDDGGGYGGGTADGGRGGGGIYTFPNGDVYEGEFKNGKPH 160

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370510869 166 GFGMFkcsTQP--VSYIGHWCNGKRHGKGSIYYnqegtcwyegdwvqnikkgwgircyKSGNIYEGQWEDNMRHGEGRMR 243
Cdd:COG4642   161 GQGTL---TYAdgDRYEGEFKNGKRHGQGTLTY-------------------------ANGDVYEGEFKNGQRHGQGTYT 212

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370510869 244 WlttneeytgrwergiQNGFgthtwflkrirssqyplrnEYIGEFVNGYRHGRGKFYYASGAMYDGEWVSNKKHGMGRLT 323
Cdd:COG4642   213 Y---------------ADGD-------------------RYEGEFKNGKRHGQGTLTYADGDRYEGEFKNGKRHGQGTMT 258

                         250
                  ....*....|...
gi 1370510869 324 FKNGRVYEGAFSN 336
Cdd:COG4642   259 YADGSVYEGEWKN 271
 
Name Accession Description Interval E-value
COG4642 COG4642
Uncharacterized conserved protein [Function unknown];
86-336 7.76e-44

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 443680 [Multi-domain]  Cd Length: 271  Bit Score: 160.12  E-value: 7.76e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370510869  86 YEGEKVRGLYEGEGFAAFQGGCTYRGMFSEGLMHGQGTYIWADGLKYEGDFVKNVPMNHGVYTWPDGSMYEGEVVNGMRN 165
Cdd:COG4642    81 GGGGKGDGGDGGGGEGGFGGGGGGGGGKKGGGGGGGGVLEGDDGGGYGGGTADGGRGGGGIYTFPNGDVYEGEFKNGKPH 160

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370510869 166 GFGMFkcsTQP--VSYIGHWCNGKRHGKGSIYYnqegtcwyegdwvqnikkgwgircyKSGNIYEGQWEDNMRHGEGRMR 243
Cdd:COG4642   161 GQGTL---TYAdgDRYEGEFKNGKRHGQGTLTY-------------------------ANGDVYEGEFKNGQRHGQGTYT 212

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370510869 244 WlttneeytgrwergiQNGFgthtwflkrirssqyplrnEYIGEFVNGYRHGRGKFYYASGAMYDGEWVSNKKHGMGRLT 323
Cdd:COG4642   213 Y---------------ADGD-------------------RYEGEFKNGKRHGQGTLTYADGDRYEGEFKNGKRHGQGTMT 258

                         250
                  ....*....|...
gi 1370510869 324 FKNGRVYEGAFSN 336
Cdd:COG4642   259 YADGSVYEGEWKN 271
PLN03185 PLN03185
phosphatidylinositol phosphate kinase; Provisional
 106-320 7.87e-27

phosphatidylinositol phosphate kinase; Provisional


Pssm-ID: 215619 [Multi-domain]  Cd Length: 765  Bit Score: 117.24  E-value: 7.87e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370510869 106 GCTYRGMFSEGLMHGQGTYIWADGLKYEGDFVKNVPMNHGVYTWPDGSMYEGEVVNGMRNGFGmfkcstqpvSYIGhwcn 185
Cdd:PLN03185    8 GDFYSGSLLGNVPEGPGKYLWSDGCMYEGEWRRGMRHGNGKISWPSGATYEGEFSGGYMHGSG---------TYTG---- 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370510869 186 gkrhgkgsiyynqEGTCWYEGDWVQNIKKGWGIRCYKSGNIYEGQWEDNMRHGEGRMRWLTTNeEYTGRWERGIQNGFGT 265
Cdd:PLN03185   75 -------------TDGTTYKGRWRLNLKHGLGYQRYPNGDVFEGSWIQGLQEGPGKYTWANGN-VYLGDMKGGKMSGKGT 140

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1370510869 266 HTWFLKrirssqyplrNEYIGEFVNGYRHGRGKFYYASGAMYDGEWVSNKKHGMG 320
Cdd:PLN03185  141 LTWVSG----------DSYEGQWLDGMMHGFGVYTWSDGGCYVGTWTRGLKDGKG 185
MORN smart00698
Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;
225-244 8.56e-05

Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;


Pssm-ID: 197832 [Multi-domain]  Cd Length: 22  Bit Score: 40.02  E-value: 8.56e-05
                           10        20
                   ....*....|....*....|
gi 1370510869  225 NIYEGQWEDNMRHGEGRMRW 244
Cdd:smart00698   1 DRYEGEWRNGKRHGRGVYTY 20
MORN pfam02493
MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple ...
 109-129 8.56e-05

MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple copies in several proteins including junctophilins (See Takeshima et al. Mol. Cell 2000;6:11-22). A MORN-repeat protein has been identified in the parasite Toxoplasma gondiis a dynamic component of cell division apparatus in Toxoplasma gondii. It has been hypothesized to functions as a linker protein between certain membrane regions and the parasite's cytoskeleton.


Pssm-ID: 308220 [Multi-domain]  Cd Length: 23  Bit Score: 40.08  E-value: 8.56e-05
                          10        20
                  ....*....|....*....|.
gi 1370510869 109 YRGMFSEGLMHGQGTYIWADG 129
Cdd:pfam02493   1 YEGEWKNGKRHGKGVYTWPDG 21
 
Name Accession Description Interval E-value
COG4642 COG4642
Uncharacterized conserved protein [Function unknown];
86-336 7.76e-44

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 443680 [Multi-domain]  Cd Length: 271  Bit Score: 160.12  E-value: 7.76e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370510869  86 YEGEKVRGLYEGEGFAAFQGGCTYRGMFSEGLMHGQGTYIWADGLKYEGDFVKNVPMNHGVYTWPDGSMYEGEVVNGMRN 165
Cdd:COG4642    81 GGGGKGDGGDGGGGEGGFGGGGGGGGGKKGGGGGGGGVLEGDDGGGYGGGTADGGRGGGGIYTFPNGDVYEGEFKNGKPH 160

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370510869 166 GFGMFkcsTQP--VSYIGHWCNGKRHGKGSIYYnqegtcwyegdwvqnikkgwgircyKSGNIYEGQWEDNMRHGEGRMR 243
Cdd:COG4642   161 GQGTL---TYAdgDRYEGEFKNGKRHGQGTLTY-------------------------ANGDVYEGEFKNGQRHGQGTYT 212

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370510869 244 WlttneeytgrwergiQNGFgthtwflkrirssqyplrnEYIGEFVNGYRHGRGKFYYASGAMYDGEWVSNKKHGMGRLT 323
Cdd:COG4642   213 Y---------------ADGD-------------------RYEGEFKNGKRHGQGTLTYADGDRYEGEFKNGKRHGQGTMT 258

                         250
                  ....*....|...
gi 1370510869 324 FKNGRVYEGAFSN 336
Cdd:COG4642   259 YADGSVYEGEWKN 271
COG4642 COG4642
Uncharacterized conserved protein [Function unknown];
97-341 8.27e-39

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 443680 [Multi-domain]  Cd Length: 271  Bit Score: 145.48  E-value: 8.27e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370510869  97 GEGFAAFQGGCTYRGMFSEGLMHGQGTYIWADGLKYEGDFVKNVPMNHGVYTWPDGSMYEGEVVNGMRNG---------- 166
Cdd:COG4642    11 GGGDATALGGGGEGGLAAAGGEGGGGLGTLPGGGGYGGGADGGGGGGGGTGVAGGGGGEGGVTAAGGGGGggggkgdggd 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370510869 167 --FGMFKCSTQPVSYIGHWCNGKRHGKGSIYYNQEGtcwYEGDWVQNIKKGWGIRCYKSGNIYEGQWEDNMRHGEGRMRW 244
Cdd:COG4642    91 ggGGEGGFGGGGGGGGGKKGGGGGGGGVLEGDDGGG---YGGGTADGGRGGGGIYTFPNGDVYEGEFKNGKPHGQGTLTY 167

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370510869 245 lTTNEEYTGRWERGIQNGFGTHTWflkrirssqyPLRNEYIGEFVNGYRHGRGKFYYASGAMYDGEWVSNKKHGMGRLTF 324
Cdd:COG4642   168 -ADGDRYEGEFKNGKRHGQGTLTY----------ANGDVYEGEFKNGQRHGQGTYTYADGDRYEGEFKNGKRHGQGTLTY 236

                         250
                  ....*....|....*..
gi 1370510869 325 KNGRVYEGAFSNDHIAG 341
Cdd:COG4642   237 ADGDRYEGEFKNGKRHG 253
PLN03185 PLN03185
phosphatidylinositol phosphate kinase; Provisional
 106-320 7.87e-27

phosphatidylinositol phosphate kinase; Provisional


Pssm-ID: 215619 [Multi-domain]  Cd Length: 765  Bit Score: 117.24  E-value: 7.87e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370510869 106 GCTYRGMFSEGLMHGQGTYIWADGLKYEGDFVKNVPMNHGVYTWPDGSMYEGEVVNGMRNGFGmfkcstqpvSYIGhwcn 185
Cdd:PLN03185    8 GDFYSGSLLGNVPEGPGKYLWSDGCMYEGEWRRGMRHGNGKISWPSGATYEGEFSGGYMHGSG---------TYTG---- 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370510869 186 gkrhgkgsiyynqEGTCWYEGDWVQNIKKGWGIRCYKSGNIYEGQWEDNMRHGEGRMRWLTTNeEYTGRWERGIQNGFGT 265
Cdd:PLN03185   75 -------------TDGTTYKGRWRLNLKHGLGYQRYPNGDVFEGSWIQGLQEGPGKYTWANGN-VYLGDMKGGKMSGKGT 140

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1370510869 266 HTWFLKrirssqyplrNEYIGEFVNGYRHGRGKFYYASGAMYDGEWVSNKKHGMG 320
Cdd:PLN03185  141 LTWVSG----------DSYEGQWLDGMMHGFGVYTWSDGGCYVGTWTRGLKDGKG 185
PLN03185 PLN03185
phosphatidylinositol phosphate kinase; Provisional
 128-335 8.01e-27

phosphatidylinositol phosphate kinase; Provisional


Pssm-ID: 215619 [Multi-domain]  Cd Length: 765  Bit Score: 117.24  E-value: 8.01e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370510869 128 DGLKYEGDFVKNVPMNHGVYTWPDGSMYEGEvvngmrngfgmfkcstqpvsyighWCNGKRHGKGSIYYNQEGTcwYEGD 207
Cdd:PLN03185    7 NGDFYSGSLLGNVPEGPGKYLWSDGCMYEGE------------------------WRRGMRHGNGKISWPSGAT--YEGE 60

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370510869 208 WVQNIKKGWGIRCYKSGNIYEGQWEDNMRHGEGRMRWlTTNEEYTGRWERGIQNGFGTHTWflkrirssqyPLRNEYIGE 287
Cdd:PLN03185   61 FSGGYMHGSGTYTGTDGTTYKGRWRLNLKHGLGYQRY-PNGDVFEGSWIQGLQEGPGKYTW----------ANGNVYLGD 129

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 1370510869 288 FVNGYRHGRGKFYYASGAMYDGEWVSNKKHGMGRLTFKNGRVYEGAFS 335
Cdd:PLN03185  130 MKGGKMSGKGTLTWVSGDSYEGQWLDGMMHGFGVYTWSDGGCYVGTWT 177
COG4642 COG4642
Uncharacterized conserved protein [Function unknown];
133-342 9.18e-26

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 443680 [Multi-domain]  Cd Length: 271  Bit Score: 107.73  E-value: 9.18e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370510869 133 EGDFVKNVPMNHGVYTWPDGSMYEGEVVNGMRNGFGMFKCSTQPVSYIGHWCNGKRHGKGSIYYNQEGtcwYEGDWVQNI 212
Cdd:COG4642     1 GGSVAEDGAGGGGDATALGGGGEGGLAAAGGEGGGGLGTLPGGGGYGGGADGGGGGGGGTGVAGGGGG---EGGVTAAGG 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370510869 213 KKGWGIRCYKSGNIYEGQWEDNMRHGEGRmrwLTTNEEYTGRWERGIQNGFGTHTWFLKRIRSSQ----YPLRNEYIGEF 288
Cdd:COG4642    78 GGGGGGGKGDGGDGGGGEGGFGGGGGGGG---GKKGGGGGGGGVLEGDDGGGYGGGTADGGRGGGgiytFPNGDVYEGEF 154

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1370510869 289 VNGYRHGRGKFYYASGAMYDGEWVSNKKHGMGRLTFKNGRVYEGAFSNDHIAGF 342
Cdd:COG4642   155 KNGKPHGQGTLTYADGDRYEGEFKNGKRHGQGTLTYANGDVYEGEFKNGQRHGQ 208
PLN03185 PLN03185
phosphatidylinositol phosphate kinase; Provisional
 86-265 3.92e-24

phosphatidylinositol phosphate kinase; Provisional


Pssm-ID: 215619 [Multi-domain]  Cd Length: 765  Bit Score: 108.77  E-value: 3.92e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370510869  86 YEGEKVRGLYEGEGFAAFQGGCTYRGMFSEGLMHGQGTYIWADGLKYEGDFVKNVPMNHGVYTWPDGSMYEGEVVNGMRN 165
Cdd:PLN03185   34 YEGEWRRGMRHGNGKISWPSGATYEGEFSGGYMHGSGTYTGTDGTTYKGRWRLNLKHGLGYQRYPNGDVFEGSWIQGLQE 113

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370510869 166 GFGMFKCSTQPVsYIGHWCNGKRHGKGSIyynqegtcwyegDWVqnikkgwgircykSGNIYEGQWEDNMRHGEGRMRWl 245
Cdd:PLN03185  114 GPGKYTWANGNV-YLGDMKGGKMSGKGTL------------TWV-------------SGDSYEGQWLDGMMHGFGVYTW- 166

                         170       180
                  ....*....|....*....|
gi 1370510869 246 TTNEEYTGRWERGIQNGFGT 265
Cdd:PLN03185  167 SDGGCYVGTWTRGLKDGKGV 186
PLN03185 PLN03185
phosphatidylinositol phosphate kinase; Provisional
 84-300 3.21e-23

phosphatidylinositol phosphate kinase; Provisional


Pssm-ID: 215619 [Multi-domain]  Cd Length: 765  Bit Score: 105.69  E-value: 3.21e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370510869  84 ESYEGEKVRGLYEGEGFAAFQGGCTYRGMFSEGLMHGQGTYIWADGLKYEGDFVKNVPMNHGVYTWPDGSMYEGEVVNGM 163
Cdd:PLN03185    9 DFYSGSLLGNVPEGPGKYLWSDGCMYEGEWRRGMRHGNGKISWPSGATYEGEFSGGYMHGSGTYTGTDGTTYKGRWRLNL 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370510869 164 RNGFGMfkcstqpvsyighwcngKRHGKGSIyynqegtcwYEGDWVQNIKKGWGIRCYKSGNIYEGQWEDNMRHGEGRMR 243
Cdd:PLN03185   89 KHGLGY-----------------QRYPNGDV---------FEGSWIQGLQEGPGKYTWANGNVYLGDMKGGKMSGKGTLT 142

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370510869 244 WlTTNEEYTGRWERGIQNGFGTHTWflkrirssqyplrNE---YIGEFVNGYRHGRGKFY 300
Cdd:PLN03185  143 W-VSGDSYEGQWLDGMMHGFGVYTW-------------SDggcYVGTWTRGLKDGKGVFY 188
PLN03185 PLN03185
phosphatidylinositol phosphate kinase; Provisional
 279-342 2.31e-08

phosphatidylinositol phosphate kinase; Provisional


Pssm-ID: 215619 [Multi-domain]  Cd Length: 765  Bit Score: 57.92  E-value: 2.31e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1370510869 279 PLRNEYIGEFVNGYRHGRGKFYYASGAMYDGEWVSNKKHGMGRLTFKNGRVYEGAFSNDHIAGF 342
Cdd:PLN03185    6 SNGDFYSGSLLGNVPEGPGKYLWSDGCMYEGEWRRGMRHGNGKISWPSGATYEGEFSGGYMHGS 69
YwqK COG2849
Antitoxin component YwqK of the YwqJK toxin-antitoxin module [Defense mechanisms];
155-337 2.38e-05

Antitoxin component YwqK of the YwqJK toxin-antitoxin module [Defense mechanisms];


Pssm-ID: 442097 [Multi-domain]  Cd Length: 163  Bit Score: 45.44  E-value: 2.38e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370510869 155 YEGEVVNGMRNGFGMFKCSTQPVSYIGHWCNGKRHGKGSIYYNQEGTCWYEGDWvqniKKGWGIRCYKSGNI-YEGQWED 233
Cdd:COG2849    12 YLLSLKLKYELGDTLLEKNGYKSGVKEKTEDSYNEGGKLIKKKLGKGLGKYKKG----KLGEWKTYYPNGQLkSEGTYKN 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370510869 234 NMRHGEGRMRWlttneeytgrwergiQNGfgthtwflkRIRSsqyplrneyIGEFVNGYRHGRGKFYYASGA-MYDGEWV 312
Cdd:COG2849    88 GKLEGEWKEYY---------------ENG---------KLKS---------EGNYKNGKLHGEWKEYYENGKlKEEGNYK 134

                         170       180
                  ....*....|....*....|....*.
gi 1370510869 313 SNKKHGMGRLTFKNGR-VYEGAFSND 337
Cdd:COG2849   135 NGKKDGVWKYYDENGKlVKEEEYKNG 160
MORN smart00698
Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;
225-244 8.56e-05

Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;


Pssm-ID: 197832 [Multi-domain]  Cd Length: 22  Bit Score: 40.02  E-value: 8.56e-05
                           10        20
                   ....*....|....*....|
gi 1370510869  225 NIYEGQWEDNMRHGEGRMRW 244
Cdd:smart00698   1 DRYEGEWRNGKRHGRGVYTY 20
MORN pfam02493
MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple ...
 109-129 8.56e-05

MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple copies in several proteins including junctophilins (See Takeshima et al. Mol. Cell 2000;6:11-22). A MORN-repeat protein has been identified in the parasite Toxoplasma gondiis a dynamic component of cell division apparatus in Toxoplasma gondii. It has been hypothesized to functions as a linker protein between certain membrane regions and the parasite's cytoskeleton.


Pssm-ID: 308220 [Multi-domain]  Cd Length: 23  Bit Score: 40.08  E-value: 8.56e-05
                          10        20
                  ....*....|....*....|.
gi 1370510869 109 YRGMFSEGLMHGQGTYIWADG 129
Cdd:pfam02493   1 YEGEWKNGKRHGKGVYTWPDG 21
MORN smart00698
Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;
107-128 2.05e-04

Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;


Pssm-ID: 197832 [Multi-domain]  Cd Length: 22  Bit Score: 38.86  E-value: 2.05e-04
                           10        20
                   ....*....|....*....|..
gi 1370510869  107 CTYRGMFSEGLMHGQGTYIWAD 128
Cdd:smart00698   1 DRYEGEWRNGKRHGRGVYTYAN 22
YwqK COG2849
Antitoxin component YwqK of the YwqJK toxin-antitoxin module [Defense mechanisms];
53-208 2.20e-04

Antitoxin component YwqK of the YwqJK toxin-antitoxin module [Defense mechanisms];


Pssm-ID: 442097 [Multi-domain]  Cd Length: 163  Bit Score: 42.75  E-value: 2.20e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370510869  53 NEVKPKKDRQNVQQNEDASQYEESILTKLIVESYEGEKVRGLYEGEGFAAFQGGCTYRGMFSEGLMHGQGTYIWADG-LK 131
Cdd:COG2849     1 KKKEGLLKISKYLLSLKLKYELGDTLLEKNGYKSGVKEKTEDSYNEGGKLIKKKLGKGLGKYKKGKLGEWKTYYPNGqLK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370510869 132 YEGDFVKNVPmnHGVYT--WPDGSM-YEGEVVNGMRNGFGMFKCSTQPVSYIGHWCNGKRHGKgSIYYNQEGTCWYEGDW 208
Cdd:COG2849    81 SEGTYKNGKL--EGEWKeyYENGKLkSEGNYKNGKLHGEWKEYYENGKLKEEGNYKNGKKDGV-WKYYDENGKLVKEEEY 157
MORN pfam02493
MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple ...
 284-306 2.64e-04

MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple copies in several proteins including junctophilins (See Takeshima et al. Mol. Cell 2000;6:11-22). A MORN-repeat protein has been identified in the parasite Toxoplasma gondiis a dynamic component of cell division apparatus in Toxoplasma gondii. It has been hypothesized to functions as a linker protein between certain membrane regions and the parasite's cytoskeleton.


Pssm-ID: 308220 [Multi-domain]  Cd Length: 23  Bit Score: 38.54  E-value: 2.64e-04
                          10        20
                  ....*....|....*....|...
gi 1370510869 284 YIGEFVNGYRHGRGKFYYASGAM 306
Cdd:pfam02493   1 YEGEWKNGKRHGKGVYTWPDGDR 23
MORN pfam02493
MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple ...
 132-154 7.69e-04

MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple copies in several proteins including junctophilins (See Takeshima et al. Mol. Cell 2000;6:11-22). A MORN-repeat protein has been identified in the parasite Toxoplasma gondiis a dynamic component of cell division apparatus in Toxoplasma gondii. It has been hypothesized to functions as a linker protein between certain membrane regions and the parasite's cytoskeleton.


Pssm-ID: 308220 [Multi-domain]  Cd Length: 23  Bit Score: 37.39  E-value: 7.69e-04
                          10        20
                  ....*....|....*....|...
gi 1370510869 132 YEGDFVKNVPMNHGVYTWPDGSM 154
Cdd:pfam02493   1 YEGEWKNGKRHGKGVYTWPDGDR 23
MORN smart00698
Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;
282-302 8.56e-04

Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;


Pssm-ID: 197832 [Multi-domain]  Cd Length: 22  Bit Score: 37.32  E-value: 8.56e-04
                           10        20
                   ....*....|....*....|.
gi 1370510869  282 NEYIGEFVNGYRHGRGKFYYA 302
Cdd:smart00698   1 DRYEGEWRNGKRHGRGVYTYA 21
MORN smart00698
Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;
305-326 1.14e-03

Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;


Pssm-ID: 197832 [Multi-domain]  Cd Length: 22  Bit Score: 36.93  E-value: 1.14e-03
                           10        20
                   ....*....|....*....|..
gi 1370510869  305 AMYDGEWVSNKKHGMGRLTFKN 326
Cdd:smart00698   1 DRYEGEWRNGKRHGRGVYTYAN 22
MORN pfam02493
MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple ...
 307-327 1.56e-03

MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple copies in several proteins including junctophilins (See Takeshima et al. Mol. Cell 2000;6:11-22). A MORN-repeat protein has been identified in the parasite Toxoplasma gondiis a dynamic component of cell division apparatus in Toxoplasma gondii. It has been hypothesized to functions as a linker protein between certain membrane regions and the parasite's cytoskeleton.


Pssm-ID: 308220 [Multi-domain]  Cd Length: 23  Bit Score: 36.62  E-value: 1.56e-03
                          10        20
                  ....*....|....*....|.
gi 1370510869 307 YDGEWVSNKKHGMGRLTFKNG 327
Cdd:pfam02493   1 YEGEWKNGKRHGKGVYTWPDG 21
MORN pfam02493
MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple ...
 227-244 3.35e-03

MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple copies in several proteins including junctophilins (See Takeshima et al. Mol. Cell 2000;6:11-22). A MORN-repeat protein has been identified in the parasite Toxoplasma gondiis a dynamic component of cell division apparatus in Toxoplasma gondii. It has been hypothesized to functions as a linker protein between certain membrane regions and the parasite's cytoskeleton.


Pssm-ID: 308220 [Multi-domain]  Cd Length: 23  Bit Score: 35.46  E-value: 3.35e-03
                          10
                  ....*....|....*...
gi 1370510869 227 YEGQWEDNMRHGEGRMRW 244
Cdd:pfam02493   1 YEGEWKNGKRHGKGVYTW 18
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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