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Conserved domains on  [gi|1218215611|ref|XP_021701945|]
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beta-mannosidase [Aedes aegypti]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
LacZ super family cl43822
Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism];
107-485 7.82e-55

Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism];


The actual alignment was detected with superfamily member COG3250:

Pssm-ID: 442481 [Multi-domain]  Cd Length: 638  Bit Score: 201.53  E-value: 7.82e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1218215611 107 NVVLTLHGVDTFAKVYLNDELLGETSNMFVRYRFNVKNVLRnECKNVpeLRIHIRSPVSEASLLAasydhlkvvpecppa 186
Cdd:COG3250    70 RVFLHFEGVDTAAEVWVNGKKVGYHEGGFTPFEFDITDYLK-PGENV--LAVRVDNPSDGSYLEG--------------- 131
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1218215611 187 ryngechvnmirkmqasfaWDWglaVPSMGLWKPVRLEYYESAKIRDITFALFDDETNWRMVVGVYLE-TGTIRRRLQGT 265
Cdd:COG3250   132 -------------------QDW---WRTSGIYRDVWLEATPKVHIEDVFVTPDLDDGSATLTVEVELEnESDAGVTVEVT 189
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1218215611 266 LmFKILGVQLENEIINVDKNSDDSGELFVEHTLKvnktAVDLWWPNgygRQKLYNLYVkwednainnvQLHDREAMIDEK 345
Cdd:COG3250   190 L-LDADGKVVATATAKVTLAAGEENTVTLTLTVP----NPKLWSPE---DPNLYTLVV----------TLKDDGKVVDTV 251
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1218215611 346 LIRIGFRTIKLSQErtsdglmFYFIVNDVPMFMKGSNWIPS-----SVLPESSYDEnyvqfLLCAARDANMNMLRVWGGg 420
Cdd:COG3250   252 STRFGFRTIEIDGD-------GGFLLNGKPVFLKGVNRHEDwpddgRAVTDEAMRR-----DLELMKEAGFNAVRTSHY- 318
                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1218215611 421 vYESDYFYQLADELGILIWHDMMFACS-MYPANEAFLSNVKVEVIQNVRRIQYHPSIAIWATNNEN 485
Cdd:COG3250   319 -PEDPEFYDLCDELGLLVWDEAPFEWHgMLGDDPEFLEAVEAELREMVRRDRNHPSIILWSGGNES 383
Mannosidase_ig pfam17786
Mannosidase Ig/CBM-like domain; This domain corresponds to domain 4 in the structure of ...
719-808 5.16e-08

Mannosidase Ig/CBM-like domain; This domain corresponds to domain 4 in the structure of Bacteroides thetaiotaomicron beta-mannosidase, BtMan2A. This domain has an Ig-like fold.


:

Pssm-ID: 465505  Cd Length: 90  Bit Score: 51.03  E-value: 5.16e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1218215611 719 NKLDVYLVRDTLGSDElWSVEVNIHQWDKFMRVDNLTfgAIKVPENTVVRIGSYDIYDHLrqKNMDPKEHLLLINLLRDG 798
Cdd:pfam17786   1 GKLEVWVVNDTLEPVK-GTLELRLIDFDGKVLYERTV--DVTVPANSSTEVASLDFAELL--GGADPRSVVLVARLLADG 75
                          90
                  ....*....|...
gi 1218215611 799 TKIAEN---FVPL 808
Cdd:pfam17786  76 EVLARNvyyFVPP 88
 
Name Accession Description Interval E-value
LacZ COG3250
Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism];
107-485 7.82e-55

Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism];


Pssm-ID: 442481 [Multi-domain]  Cd Length: 638  Bit Score: 201.53  E-value: 7.82e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1218215611 107 NVVLTLHGVDTFAKVYLNDELLGETSNMFVRYRFNVKNVLRnECKNVpeLRIHIRSPVSEASLLAasydhlkvvpecppa 186
Cdd:COG3250    70 RVFLHFEGVDTAAEVWVNGKKVGYHEGGFTPFEFDITDYLK-PGENV--LAVRVDNPSDGSYLEG--------------- 131
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1218215611 187 ryngechvnmirkmqasfaWDWglaVPSMGLWKPVRLEYYESAKIRDITFALFDDETNWRMVVGVYLE-TGTIRRRLQGT 265
Cdd:COG3250   132 -------------------QDW---WRTSGIYRDVWLEATPKVHIEDVFVTPDLDDGSATLTVEVELEnESDAGVTVEVT 189
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1218215611 266 LmFKILGVQLENEIINVDKNSDDSGELFVEHTLKvnktAVDLWWPNgygRQKLYNLYVkwednainnvQLHDREAMIDEK 345
Cdd:COG3250   190 L-LDADGKVVATATAKVTLAAGEENTVTLTLTVP----NPKLWSPE---DPNLYTLVV----------TLKDDGKVVDTV 251
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1218215611 346 LIRIGFRTIKLSQErtsdglmFYFIVNDVPMFMKGSNWIPS-----SVLPESSYDEnyvqfLLCAARDANMNMLRVWGGg 420
Cdd:COG3250   252 STRFGFRTIEIDGD-------GGFLLNGKPVFLKGVNRHEDwpddgRAVTDEAMRR-----DLELMKEAGFNAVRTSHY- 318
                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1218215611 421 vYESDYFYQLADELGILIWHDMMFACS-MYPANEAFLSNVKVEVIQNVRRIQYHPSIAIWATNNEN 485
Cdd:COG3250   319 -PEDPEFYDLCDELGLLVWDEAPFEWHgMLGDDPEFLEAVEAELREMVRRDRNHPSIILWSGGNES 383
Mannosidase_ig pfam17786
Mannosidase Ig/CBM-like domain; This domain corresponds to domain 4 in the structure of ...
719-808 5.16e-08

Mannosidase Ig/CBM-like domain; This domain corresponds to domain 4 in the structure of Bacteroides thetaiotaomicron beta-mannosidase, BtMan2A. This domain has an Ig-like fold.


Pssm-ID: 465505  Cd Length: 90  Bit Score: 51.03  E-value: 5.16e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1218215611 719 NKLDVYLVRDTLGSDElWSVEVNIHQWDKFMRVDNLTfgAIKVPENTVVRIGSYDIYDHLrqKNMDPKEHLLLINLLRDG 798
Cdd:pfam17786   1 GKLEVWVVNDTLEPVK-GTLELRLIDFDGKVLYERTV--DVTVPANSSTEVASLDFAELL--GGADPRSVVLVARLLADG 75
                          90
                  ....*....|...
gi 1218215611 799 TKIAEN---FVPL 808
Cdd:pfam17786  76 EVLARNvyyFVPP 88
 
Name Accession Description Interval E-value
LacZ COG3250
Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism];
107-485 7.82e-55

Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism];


Pssm-ID: 442481 [Multi-domain]  Cd Length: 638  Bit Score: 201.53  E-value: 7.82e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1218215611 107 NVVLTLHGVDTFAKVYLNDELLGETSNMFVRYRFNVKNVLRnECKNVpeLRIHIRSPVSEASLLAasydhlkvvpecppa 186
Cdd:COG3250    70 RVFLHFEGVDTAAEVWVNGKKVGYHEGGFTPFEFDITDYLK-PGENV--LAVRVDNPSDGSYLEG--------------- 131
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1218215611 187 ryngechvnmirkmqasfaWDWglaVPSMGLWKPVRLEYYESAKIRDITFALFDDETNWRMVVGVYLE-TGTIRRRLQGT 265
Cdd:COG3250   132 -------------------QDW---WRTSGIYRDVWLEATPKVHIEDVFVTPDLDDGSATLTVEVELEnESDAGVTVEVT 189
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1218215611 266 LmFKILGVQLENEIINVDKNSDDSGELFVEHTLKvnktAVDLWWPNgygRQKLYNLYVkwednainnvQLHDREAMIDEK 345
Cdd:COG3250   190 L-LDADGKVVATATAKVTLAAGEENTVTLTLTVP----NPKLWSPE---DPNLYTLVV----------TLKDDGKVVDTV 251
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1218215611 346 LIRIGFRTIKLSQErtsdglmFYFIVNDVPMFMKGSNWIPS-----SVLPESSYDEnyvqfLLCAARDANMNMLRVWGGg 420
Cdd:COG3250   252 STRFGFRTIEIDGD-------GGFLLNGKPVFLKGVNRHEDwpddgRAVTDEAMRR-----DLELMKEAGFNAVRTSHY- 318
                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1218215611 421 vYESDYFYQLADELGILIWHDMMFACS-MYPANEAFLSNVKVEVIQNVRRIQYHPSIAIWATNNEN 485
Cdd:COG3250   319 -PEDPEFYDLCDELGLLVWDEAPFEWHgMLGDDPEFLEAVEAELREMVRRDRNHPSIILWSGGNES 383
Mannosidase_ig pfam17786
Mannosidase Ig/CBM-like domain; This domain corresponds to domain 4 in the structure of ...
719-808 5.16e-08

Mannosidase Ig/CBM-like domain; This domain corresponds to domain 4 in the structure of Bacteroides thetaiotaomicron beta-mannosidase, BtMan2A. This domain has an Ig-like fold.


Pssm-ID: 465505  Cd Length: 90  Bit Score: 51.03  E-value: 5.16e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1218215611 719 NKLDVYLVRDTLGSDElWSVEVNIHQWDKFMRVDNLTfgAIKVPENTVVRIGSYDIYDHLrqKNMDPKEHLLLINLLRDG 798
Cdd:pfam17786   1 GKLEVWVVNDTLEPVK-GTLELRLIDFDGKVLYERTV--DVTVPANSSTEVASLDFAELL--GGADPRSVVLVARLLADG 75
                          90
                  ....*....|...
gi 1218215611 799 TKIAEN---FVPL 808
Cdd:pfam17786  76 EVLARNvyyFVPP 88
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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