NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1207189697|ref|XP_021327955|]
View 

protocadherin-16 [Danio rerio]

Protein Classification

cadherin repeat domain-containing protein( domain architecture ID 10182011)

cadherin repeat domain-containing protein similar to Homo sapiens desmoglein-2, which is involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion; cadherins are are calcium-dependent cell adhesion proteins that preferentially interact with themselves in connecting cells

CATH:  2.60.40.60
Gene Ontology:  GO:0007156|GO:0005509
PubMed:  17158740|28268172|27782885|11736639
SCOP:  4007535

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1123-1213 1.25e-33

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 126.27  E-value: 1.25e-33
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697 1123 VRENLPAGTGFGRVSATDRDAGLNSRLTYRLL--HTDRYFQINSQTGEISTRAALDREHQSSYQLMVVVQDGGTPPRSAT 1200
Cdd:cd11304      6 VPENAPPGTVVLTVSATDPDSGENGEVTYSIVsgNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPPLSST 85

                           90
                   ....*....|...
gi 1207189697 1201 GTAHITVLDENDN 1213
Cdd:cd11304     86 ATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1652-1746 1.37e-33

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 125.89  E-value: 1.37e-33
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697 1652 EFEAQIRENQPAGTSIIQVTASDRDHGTNGLVTY---GGVTEDGFTINAETGVISATRVLDRELQDHYTITVYAKDGGIP 1728
Cdd:cd11304      1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYsivSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGP 80

                           90
                   ....*....|....*...
gi 1207189697 1729 PNFAKAKVHITVLDENDN 1746
Cdd:cd11304     81 PLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1550-1643 8.66e-33

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 123.58  E-value: 8.66e-33
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697 1550 VSVMEDQPVGFVLLYVMAWDADQGENGRVSYRIQSGNTAGRFVLSSNSGSLSILKPLDREEQESYNLTIVAEDHGIPQHS 1629
Cdd:cd11304      4 VSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPPLS 83

                           90
                   ....*....|....
gi 1207189697 1630 TTQVLSIQVIDVND 1643
Cdd:cd11304     84 STATVTITVLDVND 97
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1754-1850 1.09e-32

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 123.58  E-value: 1.09e-32
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697 1754 QYSLEVPENLQP-VELFTLKATDRDIGESGRLEYKIKAGDPDGDFRLDGSSGALSTSRPLDRERKSSYSLQVVVQDHGSP 1832
Cdd:cd11304      1 SYEVSVPENAPPgTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGP 80

                           90
                   ....*....|....*...
gi 1207189697 1833 SLNSTASVEISVLDVNDN 1850
Cdd:cd11304     81 PLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 478-576 2.20e-31

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 119.73  E-value: 2.20e-31
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697  478 YKQTIPEVVYPGSFVLQVTARDKDQGPNGDIRYSILPDkkTHSSWFTIDPVTGIITTATKLDYETNPKPSIKVVATDGGR 557
Cdd:cd11304      2 YEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSG--NEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGG 79

                           90
                   ....*....|....*....
gi 1207189697  558 PPLSSTAVVEIDLQDTNDN 576
Cdd:cd11304     80 PPLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2376-2472 1.81e-30

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 117.03  E-value: 1.81e-30
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697 2376 YQVTLPEHSPPGSPVITVTATDRDSGENGKVSYRVLSSTRDG-FYVDPKNGTLFIRQkaKFDPEE-PSVSIVIEARDGGS 2453
Cdd:cd11304      2 YEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGlFSIDPSTGEITTAK--PLDREEqSSYTLTVTATDGGG 79

                           90
                   ....*....|....*....
gi 1207189697 2454 PPLSSSATVQVQLMDVNDN 2472
Cdd:cd11304     80 PPLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 261-359 9.07e-30

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 115.10  E-value: 9.07e-30
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697  261 YNAIISESLPQGSNILQVFASDADEGDNGLVLYEInrRQSDPDRYFVIDPRSGIITLNKALDYEMRKVHELVVQAKDNAS 340
Cdd:cd11304      2 YEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSI--VSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGG 79

                           90
                   ....*....|....*....
gi 1207189697  341 HPEITNAFVTIHVRDYNDN 359
Cdd:cd11304     80 PPLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1858-1955 6.52e-29

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 112.79  E-value: 6.52e-29
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697 1858 SYTVDVSEDAAIGLVVLDATATDVDEGQNGQILYFL-SQEAKGAFTVDPNTGRITTAALLDREKRASYFFQVYAVDLSPa 1936
Cdd:cd11304      1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIvSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGG- 79

                           90
                   ....*....|....*....
gi 1207189697 1937 APRNSTAQVTVTILDVNDN 1955
Cdd:cd11304     80 PPLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2597-2692 4.73e-28

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 110.10  E-value: 4.73e-28
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697 2597 EYIVALSEGAAAGAEILRVTATDPDSAPYAEVQYSISSGDDMKLFSVDQWTGAMKLQRPLDRESQNSHVVIVQASDGHG- 2675
Cdd:cd11304      1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGp 80

                           90
                   ....*....|....*...
gi 1207189697 2676 -RFALAPISVEVKDINDN 2692
Cdd:cd11304     81 pLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2171-2267 1.23e-26

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 106.24  E-value: 1.23e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697 2171 YVTYMHEAQGYDFPIIQVVAEDVDQGQNGQVTYTIESSNQSGLFKIDPQTGSITTTAIMDREIWTQAKLVIKATDRGSPK 2250
Cdd:cd11304      2 YEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPP 81

                           90
                   ....*....|....*..
gi 1207189697 2251 LVGTATITVIIVDLNDN 2267
Cdd:cd11304     82 LSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 796-891 1.74e-25

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 102.78  E-value: 1.74e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697  796 QYFFTVSEDVLRGTEVGVVRASSR-NGVSKDVTYTISAGDPDGYFMVDPETGALRTSLPLDHESRPFFDLEIQAR-SGSP 873
Cdd:cd11304      1 SYEVSVPENAPPGTVVLTVSATDPdSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATdGGGP 80

                           90
                   ....*....|....*...
gi 1207189697  874 PAFGDTRVRVTIADVNDN 891
Cdd:cd11304     81 PLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2480-2589 2.54e-25

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 102.39  E-value: 2.54e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697 2480 EYKATVSEDQLPGATILTLEAVDGDlSQENSGFDFAIASGNVGNAFQIESsvrfieghgfqTVGTLILAERLDFEALSHY 2559
Cdd:cd11304      1 SYEVSVPENAPPGTVVLTVSATDPD-SGENGEVTYSIVSGNEDGLFSIDP-----------STGEITTAKPLDREEQSSY 68

                           90       100       110
                   ....*....|....*....|....*....|
gi 1207189697 2560 NLTVSVSDRGVPQRSSSVPAIITVTDVNDN 2589
Cdd:cd11304     69 TLTVTATDGGGPPLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1228-1316 1.04e-24

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 100.85  E-value: 1.04e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697 1228 IQVQEGLPAGSLLGTLNAKDPDEGENGTIFYSL-SGSRAERFSLNPNTGELRSSSPLRRAEKAEYSFTITASDRGAPSQS 1306
Cdd:cd11304      4 VSVPENAPPGTVVLTVSATDPDSGENGEVTYSIvSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPPLS 83

                           90
                   ....*....|
gi 1207189697 1307 SSAVLLIQVI 1316
Cdd:cd11304     84 STATVTITVL 93
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1437-1540 1.16e-24

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 100.47  E-value: 1.16e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697 1437 PVTIVIPENTQAGSSVYTFQATDKDgSGPNSEIRYSVQQrwPDNPDLFNLDPVTGVLKLGRELDHEETSSLFLVVQAMDS 1516
Cdd:cd11304      1 SYEVSVPENAPPGTVVLTVSATDPD-SGENGEVTYSIVS--GNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDG 77

                           90       100
                   ....*....|....*....|....
gi 1207189697 1517 AldpNQRLWGSVTARVFVTDENDN 1540
Cdd:cd11304     78 G---GPPLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 375-469 1.86e-24

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 100.08  E-value: 1.86e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697  375 QISEGAQPGQYVARISVSDPDYGEYSNVNVSLEGGD--GKFALttkDSIIYLIYVDQILDREERDSYELRVMATDSGTPP 452
Cdd:cd11304      5 SVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNedGLFSI---DPSTGEITTAKPLDREEQSSYTLTVTATDGGGPP 81

                           90
                   ....*....|....*..
gi 1207189697  453 LHAESSFTIHVTDVNDN 469
Cdd:cd11304     82 LSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 905-995 1.73e-22

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 94.30  E-value: 1.73e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697  905 LPEATKMGTIVYRVQAEDRDSGPNGQLSFDLISSGGQRTFGVERSSGEVRLIGSLSYDSVPRYDLQVIAKDSGAPQLSAT 984
Cdd:cd11304      6 VPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPPLSST 85

                           90
                   ....*....|.
gi 1207189697  985 FSLVVHIQAEN 995
Cdd:cd11304     86 ATVTITVLDVN 96
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1005-1110 7.72e-22

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 92.38  E-value: 7.72e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697 1005 TYRVELKENTPLNTNFLQVRALNRDPNGNGgsstptsTLAYRLRPDGDAVGFGIAPDSGWLFVKSALDREVKDIYLLTVL 1084
Cdd:cd11304      1 SYEVSVPENAPPGTVVLTVSATDPDSGENG-------EVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVT 73

                           90       100
                   ....*....|....*....|....*.
gi 1207189697 1085 ATSGsGQMGRTGSATIRVSVTDENDN 1110
Cdd:cd11304     74 ATDG-GGPPLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 585-683 5.46e-20

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 87.37  E-value: 5.46e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697  585 YNVSIKENTSAGTCFLEVKADDADGGSFGTITYSIGSGSvsaPLSQFSINKESGQICTSTALDRdEGADSFHFTVTATDG 664
Cdd:cd11304      2 YEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGN---EDGLFSIDPSTGEITTAKPLDR-EEQSSYTLTVTATDG 77

                           90       100
                   ....*....|....*....|.
gi 1207189697  665 GGLSSSASVLV--SLEDINDN 683
Cdd:cd11304     78 GGPPLSSTATVtiTVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2702-2796 5.52e-20

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 87.37  E-value: 5.52e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697 2702 TASIRENQPLNSAVTVLHAIDYDTGVYGQLKYYLMDHSSPGkdLFFVDQNSGEVRTKQIFDFEKVNSFNFIALAVDAGNN 2781
Cdd:cd11304      3 EVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDG--LFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGP 80

                           90
                   ....*....|....*
gi 1207189697 2782 SATVTVQVFITGEDE 2796
Cdd:cd11304     81 PLSSTATVTITVLDV 95
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 692-783 2.16e-18

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 82.75  E-value: 2.16e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697  692 YAVSLSTQSSPGTSVIRVTAHDPDAGANGRVTYHTVSGGGSSFFTLNKDTGVISLSRSLHGKANSVIPMVISARDGGGLT 771
Cdd:cd11304      2 YEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPP 81

                           90
                   ....*....|..
gi 1207189697  772 APVNARVNISVV 783
Cdd:cd11304     82 LSSTATVTITVL 93
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 150-252 2.89e-18

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 82.36  E-value: 2.89e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697  150 SLKIPEQTAVGTKFSLEPATDSDKDQLTVQGYQIKEGNVGQVFRLETKraankvlYLDLVVNGVLDREKRSSYSLVVEAF 229
Cdd:cd11304      3 EVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPS-------TGEITTAKPLDREEQSSYTLTVTAT 75

                           90       100
                   ....*....|....*....|...
gi 1207189697  230 DGGSPRQNGQMTLDILVQDINDH 252
Cdd:cd11304     76 DGGGPPLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1336-1429 1.27e-17

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 80.44  E-value: 1.27e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697 1336 EGAKPGSVIGSVRAHDqREVTLNGQVTYLVVGGtDHEGTFMVDRLTGDVYLARELDYEKGSRYTLQIEVDDfSKAYPNTH 1415
Cdd:cd11304      8 ENAPPGTVVLTVSATD-PDSGENGEVTYSIVSG-NEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATD-GGGPPLSS 84

                           90
                   ....*....|....
gi 1207189697 1416 MIQLEINVQDSNDH 1429
Cdd:cd11304     85 TATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2274-2358 1.60e-17

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 80.05  E-value: 1.60e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697 2274 PREVRVPENSLIGTEITLVTGNDVDSGP--VLSYSLqLDASTQGKFDIDRYNGRVSLTAPLDYEERTWYKLTIRASDS-- 2349
Cdd:cd11304      1 SYEVSVPENAPPGTVVLTVSATDPDSGEngEVTYSI-VSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGgg 79

                           90
                   ....*....|
gi 1207189697 2350 -KHQSEANLT 2358
Cdd:cd11304     80 pPLSSTATVT 89
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2070-2162 5.10e-17

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 78.89  E-value: 5.10e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697 2070 VSLQENADKGTVVAQAQAQHPDGTRDG-INYSIFSGNKYHSFSISSNTGEIWVQSSngLDFEDTPRLRLVVKAE---TTS 2145
Cdd:cd11304      4 VSVPENAPPGTVVLTVSATDPDSGENGeVTYSIVSGNEDGLFSIDPSTGEITTAKP--LDREEQSSYTLTVTATdggGPP 81

                           90
                   ....*....|....*..
gi 1207189697 2146 SSSFMAVNLILQDVNDN 2162
Cdd:cd11304     82 LSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 50-140 6.54e-13

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 66.95  E-value: 6.54e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697   50 ELQLDEEQPAGTIVGDISA-----GLQPGVTaslYFISDHEGTGIgsdLHIDETTGIIKTARRLDREERDHYSFIAV--- 121
Cdd:cd11304      3 EVSVPENAPPGTVVLTVSAtdpdsGENGEVT---YSIVSGNEDGL---FSIDPSTGEITTAKPLDREEQSSYTLTVTatd 76

                           90       100
                   ....*....|....*....|...
gi 1207189697  122 ----TMTGfTVKVSITVNDINDH 140
Cdd:cd11304     77 gggpPLSS-TATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1977-2054 7.00e-13

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 66.95  E-value: 7.00e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697 1977 QVVATMRAEDKDFGANGSVFYRFA--MPVRGFAINSLTGAIQTTENLQTLTQTQRTLIVEAMDQGSPPQSSLGVVIIYVK 2054
Cdd:cd11304     14 TVVLTVSATDPDSGENGEVTYSIVsgNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPPLSSTATVTITVL 93
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2807-2904 5.06e-12

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 64.64  E-value: 5.06e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697 2807 SFEVPEGAKKGQSIGLVQAKDEDGGVDGIVLYSF--PNSSPYFDVNKTTGVIYLK--MDnsgsssggsrskRETR-LMTM 2881
Cdd:cd11304      3 EVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIvsGNEDGLFSIDPSTGEITTAkpLD------------REEQsSYTL 70

                           90       100
                   ....*....|....*....|...
gi 1207189697 2882 DVSAHSPLDTSRVASAQVIIDVT 2904
Cdd:cd11304     71 TVTATDGGGPPLSSTATVTITVL 93
 
Name Accession Description Interval E-value
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1123-1213 1.25e-33

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 126.27  E-value: 1.25e-33
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697 1123 VRENLPAGTGFGRVSATDRDAGLNSRLTYRLL--HTDRYFQINSQTGEISTRAALDREHQSSYQLMVVVQDGGTPPRSAT 1200
Cdd:cd11304      6 VPENAPPGTVVLTVSATDPDSGENGEVTYSIVsgNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPPLSST 85

                           90
                   ....*....|...
gi 1207189697 1201 GTAHITVLDENDN 1213
Cdd:cd11304     86 ATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1652-1746 1.37e-33

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 125.89  E-value: 1.37e-33
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697 1652 EFEAQIRENQPAGTSIIQVTASDRDHGTNGLVTY---GGVTEDGFTINAETGVISATRVLDRELQDHYTITVYAKDGGIP 1728
Cdd:cd11304      1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYsivSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGP 80

                           90
                   ....*....|....*...
gi 1207189697 1729 PNFAKAKVHITVLDENDN 1746
Cdd:cd11304     81 PLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1550-1643 8.66e-33

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 123.58  E-value: 8.66e-33
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697 1550 VSVMEDQPVGFVLLYVMAWDADQGENGRVSYRIQSGNTAGRFVLSSNSGSLSILKPLDREEQESYNLTIVAEDHGIPQHS 1629
Cdd:cd11304      4 VSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPPLS 83

                           90
                   ....*....|....
gi 1207189697 1630 TTQVLSIQVIDVND 1643
Cdd:cd11304     84 STATVTITVLDVND 97
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1754-1850 1.09e-32

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 123.58  E-value: 1.09e-32
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697 1754 QYSLEVPENLQP-VELFTLKATDRDIGESGRLEYKIKAGDPDGDFRLDGSSGALSTSRPLDRERKSSYSLQVVVQDHGSP 1832
Cdd:cd11304      1 SYEVSVPENAPPgTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGP 80

                           90
                   ....*....|....*...
gi 1207189697 1833 SLNSTASVEISVLDVNDN 1850
Cdd:cd11304     81 PLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 478-576 2.20e-31

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 119.73  E-value: 2.20e-31
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697  478 YKQTIPEVVYPGSFVLQVTARDKDQGPNGDIRYSILPDkkTHSSWFTIDPVTGIITTATKLDYETNPKPSIKVVATDGGR 557
Cdd:cd11304      2 YEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSG--NEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGG 79

                           90
                   ....*....|....*....
gi 1207189697  558 PPLSSTAVVEIDLQDTNDN 576
Cdd:cd11304     80 PPLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2376-2472 1.81e-30

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 117.03  E-value: 1.81e-30
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697 2376 YQVTLPEHSPPGSPVITVTATDRDSGENGKVSYRVLSSTRDG-FYVDPKNGTLFIRQkaKFDPEE-PSVSIVIEARDGGS 2453
Cdd:cd11304      2 YEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGlFSIDPSTGEITTAK--PLDREEqSSYTLTVTATDGGG 79

                           90
                   ....*....|....*....
gi 1207189697 2454 PPLSSSATVQVQLMDVNDN 2472
Cdd:cd11304     80 PPLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 261-359 9.07e-30

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 115.10  E-value: 9.07e-30
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697  261 YNAIISESLPQGSNILQVFASDADEGDNGLVLYEInrRQSDPDRYFVIDPRSGIITLNKALDYEMRKVHELVVQAKDNAS 340
Cdd:cd11304      2 YEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSI--VSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGG 79

                           90
                   ....*....|....*....
gi 1207189697  341 HPEITNAFVTIHVRDYNDN 359
Cdd:cd11304     80 PPLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1858-1955 6.52e-29

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 112.79  E-value: 6.52e-29
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697 1858 SYTVDVSEDAAIGLVVLDATATDVDEGQNGQILYFL-SQEAKGAFTVDPNTGRITTAALLDREKRASYFFQVYAVDLSPa 1936
Cdd:cd11304      1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIvSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGG- 79

                           90
                   ....*....|....*....
gi 1207189697 1937 APRNSTAQVTVTILDVNDN 1955
Cdd:cd11304     80 PPLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2597-2692 4.73e-28

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 110.10  E-value: 4.73e-28
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697 2597 EYIVALSEGAAAGAEILRVTATDPDSAPYAEVQYSISSGDDMKLFSVDQWTGAMKLQRPLDRESQNSHVVIVQASDGHG- 2675
Cdd:cd11304      1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGp 80

                           90
                   ....*....|....*...
gi 1207189697 2676 -RFALAPISVEVKDINDN 2692
Cdd:cd11304     81 pLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2171-2267 1.23e-26

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 106.24  E-value: 1.23e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697 2171 YVTYMHEAQGYDFPIIQVVAEDVDQGQNGQVTYTIESSNQSGLFKIDPQTGSITTTAIMDREIWTQAKLVIKATDRGSPK 2250
Cdd:cd11304      2 YEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPP 81

                           90
                   ....*....|....*..
gi 1207189697 2251 LVGTATITVIIVDLNDN 2267
Cdd:cd11304     82 LSSTATVTITVLDVNDN 98
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1137-1215 2.46e-26

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 104.74  E-value: 2.46e-26
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697  1137 SATDRDAGLNSRLTYRLL--HTDRYFQINSQTGEISTRAALDREHQSSYQLMVVVQDGGTPPRSATGTAHITVLDENDNA 1214
Cdd:smart00112    1 SATDADSGENGKVTYSILsgNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVNDNA 80


                    .
gi 1207189697  1215 P 1215
Cdd:smart00112   81 P 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1567-1646 5.56e-26

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 103.58  E-value: 5.56e-26
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697  1567 AWDADQGENGRVSYRIQSGNTAGRFVLSSNSGSLSILKPLDREEQESYNLTIVAEDHGIPQHSTTQVLSIQVIDVNDEAP 1646
Cdd:smart00112    2 ATDADSGENGKVTYSILSGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVNDNAP 81
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 796-891 1.74e-25

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 102.78  E-value: 1.74e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697  796 QYFFTVSEDVLRGTEVGVVRASSR-NGVSKDVTYTISAGDPDGYFMVDPETGALRTSLPLDHESRPFFDLEIQAR-SGSP 873
Cdd:cd11304      1 SYEVSVPENAPPGTVVLTVSATDPdSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATdGGGP 80

                           90
                   ....*....|....*...
gi 1207189697  874 PAFGDTRVRVTIADVNDN 891
Cdd:cd11304     81 PLSSTATVTITVLDVNDN 98
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 496-578 2.13e-25

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 102.04  E-value: 2.13e-25
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697   496 TARDKDQGPNGDIRYSILPDkkTHSSWFTIDPVTGIITTATKLDYETNPKPSIKVVATDGGRPPLSSTAVVEIDLQDTND 575
Cdd:smart00112    1 SATDADSGENGKVTYSILSG--NDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVND 78


                    ...
gi 1207189697   576 NEP 578
Cdd:smart00112   79 NAP 81
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2480-2589 2.54e-25

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 102.39  E-value: 2.54e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697 2480 EYKATVSEDQLPGATILTLEAVDGDlSQENSGFDFAIASGNVGNAFQIESsvrfieghgfqTVGTLILAERLDFEALSHY 2559
Cdd:cd11304      1 SYEVSVPENAPPGTVVLTVSATDPD-SGENGEVTYSIVSGNEDGLFSIDP-----------STGEITTAKPLDREEQSSY 68

                           90       100       110
                   ....*....|....*....|....*....|
gi 1207189697 2560 NLTVSVSDRGVPQRSSSVPAIITVTDVNDN 2589
Cdd:cd11304     69 TLTVTATDGGGPPLSSTATVTITVLDVNDN 98
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1772-1852 2.80e-25

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 101.66  E-value: 2.80e-25
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697  1772 KATDRDIGESGRLEYKIKAGDPDGDFRLDGSSGALSTSRPLDRERKSSYSLQVVVQDHGSPSLNSTASVEISVLDVNDNS 1851
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVNDNA 80


                    .
gi 1207189697  1852 P 1852
Cdd:smart00112   81 P 81
Cadherin pfam00028
Cadherin domain;
1123-1208 3.76e-25

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 101.61  E-value: 3.76e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697 1123 VRENLPAGTGFGRVSATDRDAGLNSRLTYRLL--HTDRYFQINSQTGEISTRAALDREHQSSYQLMVVVQDGGTPPRSAT 1200
Cdd:pfam00028    5 VPENAPVGTEVLTVTATDPDLGPNGRIFYSILggGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGPPLSST 84


                   ....*...
gi 1207189697 1201 GTAHITVL 1208
Cdd:pfam00028   85 ATVTITVL 92
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1228-1316 1.04e-24

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 100.85  E-value: 1.04e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697 1228 IQVQEGLPAGSLLGTLNAKDPDEGENGTIFYSL-SGSRAERFSLNPNTGELRSSSPLRRAEKAEYSFTITASDRGAPSQS 1306
Cdd:cd11304      4 VSVPENAPPGTVVLTVSATDPDSGENGEVTYSIvSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPPLS 83

                           90
                   ....*....|
gi 1207189697 1307 SSAVLLIQVI 1316
Cdd:cd11304     84 STATVTITVL 93
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1437-1540 1.16e-24

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 100.47  E-value: 1.16e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697 1437 PVTIVIPENTQAGSSVYTFQATDKDgSGPNSEIRYSVQQrwPDNPDLFNLDPVTGVLKLGRELDHEETSSLFLVVQAMDS 1516
Cdd:cd11304      1 SYEVSVPENAPPGTVVLTVSATDPD-SGENGEVTYSIVS--GNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDG 77

                           90       100
                   ....*....|....*....|....
gi 1207189697 1517 AldpNQRLWGSVTARVFVTDENDN 1540
Cdd:cd11304     78 G---GPPLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 375-469 1.86e-24

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 100.08  E-value: 1.86e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697  375 QISEGAQPGQYVARISVSDPDYGEYSNVNVSLEGGD--GKFALttkDSIIYLIYVDQILDREERDSYELRVMATDSGTPP 452
Cdd:cd11304      5 SVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNedGLFSI---DPSTGEITTAKPLDREEQSSYTLTVTATDGGGPP 81

                           90
                   ....*....|....*..
gi 1207189697  453 LHAESSFTIHVTDVNDN 469
Cdd:cd11304     82 LSSTATVTITVLDVNDN 98
Cadherin pfam00028
Cadherin domain;
1653-1741 1.91e-24

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 99.68  E-value: 1.91e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697 1653 FEAQIRENQPAGTSIIQVTASDRDHGTNGLVTY---GGVTEDGFTINAETGVISATRVLDRELQDHYTITVYAKDGGIPP 1729
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYsilGGGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGPP 80

                           90
                   ....*....|..
gi 1207189697 1730 NFAKAKVHITVL 1741
Cdd:pfam00028   81 LSSTATVTITVL 92
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1671-1748 2.11e-24

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 99.35  E-value: 2.11e-24
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697  1671 TASDRDHGTNGLVTY---GGVTEDGFTINAETGVISATRVLDRELQDHYTITVYAKDGGIPPNFAKAKVHITVLDENDNA 1747
Cdd:smart00112    1 SATDADSGENGKVTYsilSGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVNDNA 80


                    .
gi 1207189697  1748 P 1748
Cdd:smart00112   81 P 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 2189-2269 3.04e-23

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 95.88  E-value: 3.04e-23
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697  2189 VAEDVDQGQNGQVTYTIESSNQSGLFKIDPQTGSITTTAIMDREIWTQAKLVIKATDRGSPKLVGTATITVIIVDLNDNS 2268
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVNDNA 80


                    .
gi 1207189697  2269 P 2269
Cdd:smart00112   81 P 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1877-1957 6.12e-23

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 95.11  E-value: 6.12e-23
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697  1877 TATDVDEGQNGQILYFLSQE-AKGAFTVDPNTGRITTAALLDREKRASYFFQVYAVDLSPaAPRNSTAQVTVTILDVNDN 1955
Cdd:smart00112    1 SATDADSGENGKVTYSILSGnDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGG-PPLSSTATVTITVLDVNDN 79


                    ..
gi 1207189697  1956 AP 1957
Cdd:smart00112   80 AP 81
Cadherin pfam00028
Cadherin domain;
1550-1639 9.50e-23

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 94.67  E-value: 9.50e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697 1550 VSVMEDQPVGFVLLYVMAWDADQGENGRVSYRIQSGNTAGRFVLSSNSGSLSILKPLDREEQESYNLTIVAEDHGIPQHS 1629
Cdd:pfam00028    3 ASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGPPLS 82

                           90
                   ....*....|
gi 1207189697 1630 TTQVLSIQVI 1639
Cdd:pfam00028   83 STATVTITVL 92
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 905-995 1.73e-22

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 94.30  E-value: 1.73e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697  905 LPEATKMGTIVYRVQAEDRDSGPNGQLSFDLISSGGQRTFGVERSSGEVRLIGSLSYDSVPRYDLQVIAKDSGAPQLSAT 984
Cdd:cd11304      6 VPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPPLSST 85

                           90
                   ....*....|.
gi 1207189697  985 FSLVVHIQAEN 995
Cdd:cd11304     86 ATVTITVLDVN 96
Cadherin pfam00028
Cadherin domain;
481-571 1.88e-22

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 93.90  E-value: 1.88e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697  481 TIPEVVYPGSFVLQVTARDKDQGPNGDIRYSILPDKKTHssWFTIDPVTGIITTATKLDYETNPKPSIKVVATDGGRPPL 560
Cdd:pfam00028    4 SVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPGG--NFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGPPL 81

                           90
                   ....*....|.
gi 1207189697  561 SSTAVVEIDLQ 571
Cdd:pfam00028   82 SSTATVTITVL 92
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1005-1110 7.72e-22

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 92.38  E-value: 7.72e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697 1005 TYRVELKENTPLNTNFLQVRALNRDPNGNGgsstptsTLAYRLRPDGDAVGFGIAPDSGWLFVKSALDREVKDIYLLTVL 1084
Cdd:cd11304      1 SYEVSVPENAPPGTVVLTVSATDPDSGENG-------EVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVT 73

                           90       100
                   ....*....|....*....|....*.
gi 1207189697 1085 ATSGsGQMGRTGSATIRVSVTDENDN 1110
Cdd:cd11304     74 ATDG-GGPPLSSTATVTITVLDVNDN 98
Cadherin pfam00028
Cadherin domain;
1755-1845 1.11e-21

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 91.98  E-value: 1.11e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697 1755 YSLEVPENLQP-VELFTLKATDRDIGESGRLEYKIKAGDPDGDFRLDGSSGALSTSRPLDRERKSSYSLQVVVQDHGSPS 1833
Cdd:pfam00028    1 YSASVPENAPVgTEVLTVTATDPDLGPNGRIFYSILGGGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGPP 80

                           90
                   ....*....|..
gi 1207189697 1834 LNSTASVEISVL 1845
Cdd:pfam00028   81 LSSTATVTITVL 92
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 280-361 1.42e-21

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 91.26  E-value: 1.42e-21
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697   280 ASDADEGDNGLVLYEINrrQSDPDRYFVIDPRSGIITLNKALDYEMRKVHELVVQAKDNASHPEITNAFVTIHVRDYNDN 359
Cdd:smart00112    2 ATDADSGENGKVTYSIL--SGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVNDN 79


                    ..
gi 1207189697   360 QP 361
Cdd:smart00112   80 AP 81
Cadherin pfam00028
Cadherin domain;
1859-1950 1.73e-20

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 88.51  E-value: 1.73e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697 1859 YTVDVSEDAAIGLVVLDATATDVDEGQNGQILYF-LSQEAKGAFTVDPNTGRITTAALLDREKRASYFFQVYAVDLSPaA 1937
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYSiLGGGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGG-P 79

                           90
                   ....*....|...
gi 1207189697 1938 PRNSTAQVTVTIL 1950
Cdd:pfam00028   80 PLSSTATVTITVL 92
Cadherin pfam00028
Cadherin domain;
1228-1316 3.22e-20

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 87.74  E-value: 3.22e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697 1228 IQVQEGLPAGSLLGTLNAKDPDEGENGTIFYSLSGSRAER-FSLNPNTGELRSSSPLRRAEKAEYSFTITASDRGAPSQS 1306
Cdd:pfam00028    3 ASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPGGnFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGPPLS 82

                           90
                   ....*....|
gi 1207189697 1307 SSAVLLIQVI 1316
Cdd:pfam00028   83 STATVTITVL 92
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 2394-2474 5.10e-20

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 86.63  E-value: 5.10e-20
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697  2394 TATDRDSGENGKVSYRVLSSTRDG-FYVDPKNGTLFIrqKAKFDPEE-PSVSIVIEARDGGSPPLSSSATVQVQLMDVND 2471
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNDDGlFSIDPETGEITT--TKPLDREEqPEYTLTVEATDGGGPPLSSTATVTITVLDVND 78


                    ...
gi 1207189697  2472 NAP 2474
Cdd:smart00112   79 NAP 81
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 585-683 5.46e-20

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 87.37  E-value: 5.46e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697  585 YNVSIKENTSAGTCFLEVKADDADGGSFGTITYSIGSGSvsaPLSQFSINKESGQICTSTALDRdEGADSFHFTVTATDG 664
Cdd:cd11304      2 YEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGN---EDGLFSIDPSTGEITTAKPLDR-EEQSSYTLTVTATDG 77

                           90       100
                   ....*....|....*....|.
gi 1207189697  665 GGLSSSASVLV--SLEDINDN 683
Cdd:cd11304     78 GGPPLSSTATVtiTVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2702-2796 5.52e-20

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 87.37  E-value: 5.52e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697 2702 TASIRENQPLNSAVTVLHAIDYDTGVYGQLKYYLMDHSSPGkdLFFVDQNSGEVRTKQIFDFEKVNSFNFIALAVDAGNN 2781
Cdd:cd11304      3 EVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDG--LFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGP 80

                           90
                   ....*....|....*
gi 1207189697 2782 SATVTVQVFITGEDE 2796
Cdd:cd11304     81 PLSSTATVTITVLDV 95
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 2616-2694 7.59e-20

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 86.25  E-value: 7.59e-20
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697  2616 TATDPDSAPYAEVQYSISSGDDMKLFSVDQWTGAMKLQRPLDRESQNSHVVIVQASDGHG--RFALAPISVEVKDINDNR 2693
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGppLSSTATVTITVLDVNDNA 80


                    .
gi 1207189697  2694 P 2694
Cdd:smart00112   81 P 81
Cadherin pfam00028
Cadherin domain;
2376-2466 1.26e-19

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 85.82  E-value: 1.26e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697 2376 YQVTLPEHSPPGSPVITVTATDRDSGENGKVSYRVLSSTRDG-FYVDPKNGTLFIRQkaKFDPEEPS-VSIVIEARDGGS 2453
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPGGnFRIDPDTGDISTTK--PLDRESIGeYELTVEATDSGG 78

                           90
                   ....*....|...
gi 1207189697 2454 PPLSSSATVQVQL 2466
Cdd:pfam00028   79 PPLSSTATVTITV 91
Cadherin pfam00028
Cadherin domain;
261-353 7.17e-19

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 83.89  E-value: 7.17e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697  261 YNAIISESLPQGSNILQVFASDADEGDNGLVLYEInrRQSDPDRYFVIDPRSGIITLNKALDYEMRKVHELVVQAKDNAS 340
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYSI--LGGGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGG 78

                           90
                   ....*....|...
gi 1207189697  341 HPEITNAFVTIHV 353
Cdd:pfam00028   79 PPLSSTATVTITV 91
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 821-893 1.71e-18

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 82.40  E-value: 1.71e-18
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1207189697   821 GVSKDVTYTISAGDPDGYFMVDPETGALRTSLPLDHESRPFFDLEIQAR-SGSPPAFGDTRVRVTIADVNDNAP 893
Cdd:smart00112    8 GENGKVTYSILSGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATdGGGPPLSSTATVTITVLDVNDNAP 81
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 692-783 2.16e-18

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 82.75  E-value: 2.16e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697  692 YAVSLSTQSSPGTSVIRVTAHDPDAGANGRVTYHTVSGGGSSFFTLNKDTGVISLSRSLHGKANSVIPMVISARDGGGLT 771
Cdd:cd11304      2 YEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPP 81

                           90
                   ....*....|..
gi 1207189697  772 APVNARVNISVV 783
Cdd:cd11304     82 LSSTATVTITVL 93
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 150-252 2.89e-18

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 82.36  E-value: 2.89e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697  150 SLKIPEQTAVGTKFSLEPATDSDKDQLTVQGYQIKEGNVGQVFRLETKraankvlYLDLVVNGVLDREKRSSYSLVVEAF 229
Cdd:cd11304      3 EVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPS-------TGEITTAKPLDREEQSSYTLTVTAT 75

                           90       100
                   ....*....|....*....|...
gi 1207189697  230 DGGSPRQNGQMTLDILVQDINDH 252
Cdd:cd11304     76 DGGGPPLSSTATVTITVLDVNDN 98
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 390-471 3.29e-18

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 81.63  E-value: 3.29e-18
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697   390 SVSDPDYGEYSNVNVSLEGG--DGKFALTTKDSIIYLIyvdQILDREERDSYELRVMATDSGTPPLHAESSFTIHVTDVN 467
Cdd:smart00112    1 SATDADSGENGKVTYSILSGndDGLFSIDPETGEITTT---KPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVN 77


                    ....
gi 1207189697   468 DNPP 471
Cdd:smart00112   78 DNAP 81
Cadherin pfam00028
Cadherin domain;
2598-2686 3.94e-18

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 81.58  E-value: 3.94e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697 2598 YIVALSEGAAAGAEILRVTATDPDSAPYAEVQYSISSGDDMKLFSVDQWTGAMKLQRPLDRESQNSHVVIVQASD--GHG 2675
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDsgGPP 80

                           90
                   ....*....|.
gi 1207189697 2676 RFALAPISVEV 2686
Cdd:pfam00028   81 LSSTATVTITV 91
Cadherin pfam00028
Cadherin domain;
2184-2261 1.00e-17

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 80.42  E-value: 1.00e-17
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1207189697 2184 PIIQVVAEDVDQGQNGQVTYTIESSNQSGLFKIDPQTGSITTTAIMDREIWTQAKLVIKATDRGSPKLVGTATITVII 2261
Cdd:pfam00028   14 EVLTVTATDPDLGPNGRIFYSILGGGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGPPLSSTATVTITV 91
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1456-1542 1.10e-17

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 80.09  E-value: 1.10e-17
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697  1456 QATDKDgSGPNSEIRYSVQQrwPDNPDLFNLDPVTGVLKLGRELDHEETSSLFLVVQAMDSAldpNQRLWGSVTARVFVT 1535
Cdd:smart00112    1 SATDAD-SGENGKVTYSILS--GNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGG---GPPLSSTATVTITVL 74


                    ....*..
gi 1207189697  1536 DENDNAP 1542
Cdd:smart00112   75 DVNDNAP 81
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1336-1429 1.27e-17

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 80.44  E-value: 1.27e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697 1336 EGAKPGSVIGSVRAHDqREVTLNGQVTYLVVGGtDHEGTFMVDRLTGDVYLARELDYEKGSRYTLQIEVDDfSKAYPNTH 1415
Cdd:cd11304      8 ENAPPGTVVLTVSATD-PDSGENGEVTYSIVSG-NEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATD-GGGPPLSS 84

                           90
                   ....*....|....
gi 1207189697 1416 MIQLEINVQDSNDH 1429
Cdd:cd11304     85 TATVTITVLDVNDN 98
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 2500-2591 1.38e-17

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 79.70  E-value: 1.38e-17
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697  2500 AVDGDlSQENSGFDFAIASGNVGNAFQIESSVrfieghgfqtvGTLILAERLDFEALSHYNLTVSVSDRGVPQRSSSVPA 2579
Cdd:smart00112    2 ATDAD-SGENGKVTYSILSGNDDGLFSIDPET-----------GEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATV 69

                            90
                    ....*....|..
gi 1207189697  2580 IITVTDVNDNPP 2591
Cdd:smart00112   70 TITVLDVNDNAP 81
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2274-2358 1.60e-17

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 80.05  E-value: 1.60e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697 2274 PREVRVPENSLIGTEITLVTGNDVDSGP--VLSYSLqLDASTQGKFDIDRYNGRVSLTAPLDYEERTWYKLTIRASDS-- 2349
Cdd:cd11304      1 SYEVSVPENAPPGTVVLTVSATDPDSGEngEVTYSI-VSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGgg 79

                           90
                   ....*....|
gi 1207189697 2350 -KHQSEANLT 2358
Cdd:cd11304     80 pPLSSTATVT 89
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2070-2162 5.10e-17

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 78.89  E-value: 5.10e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697 2070 VSLQENADKGTVVAQAQAQHPDGTRDG-INYSIFSGNKYHSFSISSNTGEIWVQSSngLDFEDTPRLRLVVKAE---TTS 2145
Cdd:cd11304      4 VSVPENAPPGTVVLTVSATDPDSGENGeVTYSIVSGNEDGLFSIDPSTGEITTAKP--LDREEQSSYTLTVTATdggGPP 81

                           90
                   ....*....|....*..
gi 1207189697 2146 SSSFMAVNLILQDVNDN 2162
Cdd:cd11304     82 LSSTATVTITVLDVNDN 98
Cadherin pfam00028
Cadherin domain;
905-992 9.22e-17

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 77.73  E-value: 9.22e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697  905 LPEATKMGTIVYRVQAEDRDSGPNGQLSFDLISSGGQRTFGVERSSGEVRLIGSLSYDSVPRYDLQVIAKDSGAPQLSAT 984
Cdd:pfam00028    5 VPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGPPLSST 84


                   ....*...
gi 1207189697  985 FSLVVHIQ 992
Cdd:pfam00028   85 ATVTITVL 92
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1244-1316 2.19e-16

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 76.23  E-value: 2.19e-16
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1207189697  1244 NAKDPDEGENGTIFYSL-SGSRAERFSLNPNTGELRSSSPLRRAEKAEYSFTITASDRGAPSQSSSAVLLIQVI 1316
Cdd:smart00112    1 SATDADSGENGKVTYSIlSGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVL 74
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 919-999 5.42e-16

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 75.08  E-value: 5.42e-16
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697   919 QAEDRDSGPNGQLSFDLISSGGQRTFGVERSSGEVRLIGSLSYDSVPRYDLQVIAKDSGAPQLSATFSLVVHIQAENNQG 998
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVNDNA 80


                    .
gi 1207189697   999 P 999
Cdd:smart00112   81 P 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 168-254 1.61e-15

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 73.92  E-value: 1.61e-15
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697   168 ATDSDKDQLTVQGYQIKEGNVGQVFRLETKRAAnkvlyldLVVNGVLDREKRSSYSLVVEAFDGGSPRQNGQMTLDILVQ 247
Cdd:smart00112    2 ATDADSGENGKVTYSILSGNDDGLFSIDPETGE-------ITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVL 74


                    ....*..
gi 1207189697   248 DINDHAP 254
Cdd:smart00112   75 DVNDNAP 81
Cadherin pfam00028
Cadherin domain;
2275-2349 1.96e-15

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 73.87  E-value: 1.96e-15
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1207189697 2275 REVRVPENSLIGTEITLVTGNDVDSGP--VLSYSLQLDaSTQGKFDIDRYNGRVSLTAPLDYEERTWYKLTIRASDS 2349
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPngRIFYSILGG-GPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDS 76
Cadherin pfam00028
Cadherin domain;
2481-2584 6.01e-15

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 72.72  E-value: 6.01e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697 2481 YKATVSEDQLPGATILTLEAVDGDLSQeNSGFDFAIASGNVGNAFQIESSVrfieghgfqtvGTLILAERLDFEALSHYN 2560
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGP-NGRIFYSILGGGPGGNFRIDPDT-----------GDISTTKPLDRESIGEYE 68

                           90       100
                   ....*....|....*....|....
gi 1207189697 2561 LTVSVSDRGVPQRSSSVPAIITVT 2584
Cdd:pfam00028   69 LTVEATDSGGPPLSSTATVTITVL 92
Cadherin pfam00028
Cadherin domain;
1006-1105 6.76e-15

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 72.33  E-value: 6.76e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697 1006 YRVELKENTPLNTNFLQVRALNRDpngnggsSTPTSTLAYRLRPDGDAVGFGIAPDSGWLFVKSALDREVKDIYLLTVLA 1085
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPD-------LGPNGRIFYSILGGGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEA 73

                           90       100
                   ....*....|....*....|
gi 1207189697 1086 TSGSGQmGRTGSATIRVSVT 1105
Cdd:pfam00028   74 TDSGGP-PLSSTATVTITVL 92
Cadherin pfam00028
Cadherin domain;
797-885 1.97e-14

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 71.18  E-value: 1.97e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697  797 YFFTVSEDVLRGTEVGVVRASSRN-GVSKDVTYTISAGDPDGYFMVDPETGALRTSLPLDHESRPFFDLEIQAR-SGSPP 874
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDlGPNGRIFYSILGGGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATdSGGPP 80

                           90
                   ....*....|.
gi 1207189697  875 AFGDTRVRVTI 885
Cdd:pfam00028   81 LSSTATVTITV 91
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1041-1112 2.18e-14

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 70.84  E-value: 2.18e-14
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1207189697  1041 STLAYRLRPDGDAVGFGIAPDSGWLFVKSALDREVKDIYLLTVLATSGsGQMGRTGSATIRVSVTDENDNAP 1112
Cdd:smart00112   11 GKVTYSILSGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDG-GGPPLSSTATVTITVLDVNDNAP 81
Cadherin pfam00028
Cadherin domain;
375-464 4.38e-14

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 70.02  E-value: 4.38e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697  375 QISEGAQPGQYVARISVSDPDYGEYSNVNVSLEGG--DGKFALTTKDSIIYLIyvdQILDREERDSYELRVMATDSGTPP 452
Cdd:pfam00028    4 SVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGgpGGNFRIDPDTGDISTT---KPLDRESIGEYELTVEATDSGGPP 80

                           90
                   ....*....|..
gi 1207189697  453 LHAESSFTIHVT 464
Cdd:pfam00028   81 LSSTATVTITVL 92
Cadherin pfam00028
Cadherin domain;
1439-1535 7.86e-14

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 69.64  E-value: 7.86e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697 1439 TIVIPENTQAGSSVYTFQATDKDgSGPNSEIRYSVQQRWPDNpdLFNLDPVTGVLKLGRELDHEETSSLFLVVQAMDSAL 1518
Cdd:pfam00028    2 SASVPENAPVGTEVLTVTATDPD-LGPNGRIFYSILGGGPGG--NFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGG 78

                           90
                   ....*....|....*..
gi 1207189697 1519 DPnqrLWGSVTARVFVT 1535
Cdd:pfam00028   79 PP---LSSTATVTITVL 92
Cadherin pfam00028
Cadherin domain;
2702-2789 1.06e-13

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 69.25  E-value: 1.06e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697 2702 TASIRENQPLNSAVTVLHAIDYDTGVYGQLKYYLMDHSSPGKdlFFVDQNSGEVRTKQIFDFEKVNSFNFIALAVDAGNN 2781
Cdd:pfam00028    2 SASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPGGN--FRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGP 79

                           90
                   ....*....|..
gi 1207189697 2782 S----ATVTVQV 2789
Cdd:pfam00028   80 PlsstATVTITV 91
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 603-685 4.30e-13

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 66.99  E-value: 4.30e-13
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697   603 KADDADGGSFGTITYSIGSGSVSaplSQFSINKESGQICTSTALDRDEGaDSFHFTVTATDGGGLSSSASVLVS--LEDI 680
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNDD---GLFSIDPETGEITTTKPLDREEQ-PEYTLTVEATDGGGPPLSSTATVTitVLDV 76


                    ....*
gi 1207189697   681 NDNRP 685
Cdd:smart00112   77 NDNAP 81
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 50-140 6.54e-13

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 66.95  E-value: 6.54e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697   50 ELQLDEEQPAGTIVGDISA-----GLQPGVTaslYFISDHEGTGIgsdLHIDETTGIIKTARRLDREERDHYSFIAV--- 121
Cdd:cd11304      3 EVSVPENAPPGTVVLTVSAtdpdsGENGEVT---YSIVSGNEDGL---FSIDPSTGEITTAKPLDREEQSSYTLTVTatd 76

                           90       100
                   ....*....|....*....|...
gi 1207189697  122 ----TMTGfTVKVSITVNDINDH 140
Cdd:cd11304     77 gggpPLSS-TATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1977-2054 7.00e-13

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 66.95  E-value: 7.00e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697 1977 QVVATMRAEDKDFGANGSVFYRFA--MPVRGFAINSLTGAIQTTENLQTLTQTQRTLIVEAMDQGSPPQSSLGVVIIYVK 2054
Cdd:cd11304     14 TVVLTVSATDPDSGENGEVTYSIVsgNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPPLSSTATVTITVL 93
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1348-1431 8.11e-13

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 66.22  E-value: 8.11e-13
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697  1348 RAHDQREvTLNGQVTYLVVGGtDHEGTFMVDRLTGDVYLARELDYEKGSRYTLQIEVDDFSKAYPNTHmIQLEINVQDSN 1427
Cdd:smart00112    1 SATDADS-GENGKVTYSILSG-NDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSST-ATVTITVLDVN 77


                    ....
gi 1207189697  1428 DHAP 1431
Cdd:smart00112   78 DNAP 81
Cadherin pfam00028
Cadherin domain;
692-780 1.42e-12

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 65.78  E-value: 1.42e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697  692 YAVSLSTQSSPGTSVIRVTAHDPDAGANGRVTYHTVSGGGSSFFTLNKDTGVISLSRSLHGKANSVIPMVISARDGG--G 769
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGgpP 80

                           90
                   ....*....|.
gi 1207189697  770 LTAPVNARVNI 780
Cdd:pfam00028   81 LSSTATVTITV 91
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2807-2904 5.06e-12

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 64.64  E-value: 5.06e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697 2807 SFEVPEGAKKGQSIGLVQAKDEDGGVDGIVLYSF--PNSSPYFDVNKTTGVIYLK--MDnsgsssggsrskRETR-LMTM 2881
Cdd:cd11304      3 EVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIvsGNEDGLFSIDPSTGEITTAkpLD------------REEQsSYTL 70

                           90       100
                   ....*....|....*....|...
gi 1207189697 2882 DVSAHSPLDTSRVASAQVIIDVT 2904
Cdd:cd11304     71 TVTATDGGGPPLSSTATVTITVL 93
Cadherin pfam00028
Cadherin domain;
153-247 5.89e-12

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 64.24  E-value: 5.89e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697  153 IPEQTAVGTKFSLEPATDSDKDQLTVQGYQIKEGNVGQVFRLETKRAankvlylDLVVNGVLDREKRSSYSLVVEAFDGG 232
Cdd:pfam00028    5 VPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPGGNFRIDPDTG-------DISTTKPLDRESIGEYELTVEATDSG 77

                           90
                   ....*....|....*
gi 1207189697  233 SPRQNGQMTLDILVQ 247
Cdd:pfam00028   78 GPPLSSTATVTITVL 92
Cadherin pfam00028
Cadherin domain;
585-666 7.02e-12

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 63.86  E-value: 7.02e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697  585 YNVSIKENTSAGTCFLEVKADDADGGSFGTITYSIGSGSVSaplSQFSINKESGQICTSTALDRDEGaDSFHFTVTATDG 664
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPG---GNFRIDPDTGDISTTKPLDRESI-GEYELTVEATDS 76


                   ..
gi 1207189697  665 GG 666
Cdd:pfam00028   77 GG 78
Cadherin pfam00028
Cadherin domain;
1336-1406 9.59e-12

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 63.47  E-value: 9.59e-12
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1207189697 1336 EGAKPGSVIGSVRAHDqREVTLNGQVTYLVVGGtDHEGTFMVDRLTGDVYLARELDYEKGSRYTLQIEVDD 1406
Cdd:pfam00028    7 ENAPVGTEVLTVTATD-PDLGPNGRIFYSILGG-GPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATD 75
Cadherin pfam00028
Cadherin domain;
1977-2053 1.09e-11

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 63.47  E-value: 1.09e-11
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1207189697 1977 QVVATMRAEDKDFGANGSVFYRFAMPVRG--FAINSLTGAIQTTENLQTLTQTQRTLIVEAMDQGSPPQSSLGVVIIYV 2053
Cdd:pfam00028   13 TEVLTVTATDPDLGPNGRIFYSILGGGPGgnFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGPPLSSTATVTITV 91
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 710-783 1.56e-11

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 62.37  E-value: 1.56e-11
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1207189697   710 TAHDPDAGANGRVTYHTVSGGGSSFFTLNKDTGVISLSRSLHGKANSVIPMVISARDGGGLTAPVNARVNISVV 783
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVL 74
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 2086-2164 2.88e-11

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 61.60  E-value: 2.88e-11
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697  2086 QAQHPDGTRDG-INYSIFSGNKYHSFSISSNTGEIWVQSSngLDFEDTPRLRLVVKAE---TTSSSSFMAVNLILQDVND 2161
Cdd:smart00112    1 SATDADSGENGkVTYSILSGNDDGLFSIDPETGEITTTKP--LDREEQPEYTLTVEATdggGPPLSSTATVTITVLDVND 78


                    ...
gi 1207189697  2162 NRP 2164
Cdd:smart00112   79 NAP 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 2719-2796 3.54e-11

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 61.60  E-value: 3.54e-11
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1207189697  2719 HAIDYDTGVYGQLKYYLmdHSSPGKDLFFVDQNSGEVRTKQIFDFEKVNSFNFIALAVDAGNNSATVTVQVFITGEDE 2796
Cdd:smart00112    1 SATDADSGENGKVTYSI--LSGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDV 76
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 79-142 2.92e-10

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 58.90  E-value: 2.92e-10
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697    79 YFISDHEGTGIgsdLHIDETTGIIKTARRLDREERDHYSFIAVTMTGF------TVKVSITVNDINDHAP 142
Cdd:smart00112   15 YSILSGNDDGL---FSIDPETGEITTTKPLDREEQPEYTLTVEATDGGgpplssTATVTITVLDVNDNAP 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1983-2057 3.77e-09

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 55.82  E-value: 3.77e-09
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1207189697  1983 RAEDKDFGANGSVFYRFA--MPVRGFAINSLTGAIQTTENLQTLTQTQRTLIVEAMDQGSPPQSSLGVVIIYVKEQD 2057
Cdd:smart00112    1 SATDADSGENGKVTYSILsgNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVN 77
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 2296-2349 1.16e-08

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 54.28  E-value: 1.16e-08
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....*.
gi 1207189697  2296 DVDSGP--VLSYSLqLDASTQGKFDIDRYNGRVSLTAPLDYEERTWYKLTIRASDS 2349
Cdd:smart00112    4 DADSGEngKVTYSI-LSGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDG 58
Cadherin pfam00028
Cadherin domain;
2070-2141 2.04e-08

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 54.23  E-value: 2.04e-08
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1207189697 2070 VSLQENADKGTVVAQAQAQHPD-GTRDGINYSIFSGNKYHSFSISSNTGEIWVQSSngLDFEDTPRLRLVVKA 2141
Cdd:pfam00028    3 ASVPENAPVGTEVLTVTATDPDlGPNGRIFYSILGGGPGGNFRIDPDTGDISTTKP--LDRESIGEYELTVEA 73
Cadherin pfam00028
Cadherin domain;
52-134 1.63e-05

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 45.75  E-value: 1.63e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697   52 QLDEEQPAGTIVG-----DISAGLQPGVTaslYFISdheGTGIGSDLHIDETTGIIKTARRLDREERDHYSFIAVTMTGF 126
Cdd:pfam00028    4 SVPENAPVGTEVLtvtatDPDLGPNGRIF---YSIL---GGGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSG 77

                           90
                   ....*....|....
gi 1207189697  127 ------TVKVSITV 134
Cdd:pfam00028   78 gpplssTATVTITV 91
Cadherin pfam00028
Cadherin domain;
2807-2860 2.44e-05

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 45.37  E-value: 2.44e-05
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1207189697 2807 SFEVPEGAKKGQSIGLVQAKDEDGGVDGIVLYSF--PNSSPYFDVNKTTGVIYLKM 2860
Cdd:pfam00028    2 SASVPENAPVGTEVLTVTATDPDLGPNGRIFYSIlgGGPGGNFRIDPDTGDISTTK 57
 
Name Accession Description Interval E-value
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1123-1213 1.25e-33

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 126.27  E-value: 1.25e-33
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697 1123 VRENLPAGTGFGRVSATDRDAGLNSRLTYRLL--HTDRYFQINSQTGEISTRAALDREHQSSYQLMVVVQDGGTPPRSAT 1200
Cdd:cd11304      6 VPENAPPGTVVLTVSATDPDSGENGEVTYSIVsgNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPPLSST 85

                           90
                   ....*....|...
gi 1207189697 1201 GTAHITVLDENDN 1213
Cdd:cd11304     86 ATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1652-1746 1.37e-33

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 125.89  E-value: 1.37e-33
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697 1652 EFEAQIRENQPAGTSIIQVTASDRDHGTNGLVTY---GGVTEDGFTINAETGVISATRVLDRELQDHYTITVYAKDGGIP 1728
Cdd:cd11304      1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYsivSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGP 80

                           90
                   ....*....|....*...
gi 1207189697 1729 PNFAKAKVHITVLDENDN 1746
Cdd:cd11304     81 PLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1550-1643 8.66e-33

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 123.58  E-value: 8.66e-33
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697 1550 VSVMEDQPVGFVLLYVMAWDADQGENGRVSYRIQSGNTAGRFVLSSNSGSLSILKPLDREEQESYNLTIVAEDHGIPQHS 1629
Cdd:cd11304      4 VSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPPLS 83

                           90
                   ....*....|....
gi 1207189697 1630 TTQVLSIQVIDVND 1643
Cdd:cd11304     84 STATVTITVLDVND 97
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1754-1850 1.09e-32

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 123.58  E-value: 1.09e-32
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697 1754 QYSLEVPENLQP-VELFTLKATDRDIGESGRLEYKIKAGDPDGDFRLDGSSGALSTSRPLDRERKSSYSLQVVVQDHGSP 1832
Cdd:cd11304      1 SYEVSVPENAPPgTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGP 80

                           90
                   ....*....|....*...
gi 1207189697 1833 SLNSTASVEISVLDVNDN 1850
Cdd:cd11304     81 PLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 478-576 2.20e-31

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 119.73  E-value: 2.20e-31
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697  478 YKQTIPEVVYPGSFVLQVTARDKDQGPNGDIRYSILPDkkTHSSWFTIDPVTGIITTATKLDYETNPKPSIKVVATDGGR 557
Cdd:cd11304      2 YEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSG--NEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGG 79

                           90
                   ....*....|....*....
gi 1207189697  558 PPLSSTAVVEIDLQDTNDN 576
Cdd:cd11304     80 PPLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2376-2472 1.81e-30

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 117.03  E-value: 1.81e-30
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697 2376 YQVTLPEHSPPGSPVITVTATDRDSGENGKVSYRVLSSTRDG-FYVDPKNGTLFIRQkaKFDPEE-PSVSIVIEARDGGS 2453
Cdd:cd11304      2 YEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGlFSIDPSTGEITTAK--PLDREEqSSYTLTVTATDGGG 79

                           90
                   ....*....|....*....
gi 1207189697 2454 PPLSSSATVQVQLMDVNDN 2472
Cdd:cd11304     80 PPLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 261-359 9.07e-30

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 115.10  E-value: 9.07e-30
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697  261 YNAIISESLPQGSNILQVFASDADEGDNGLVLYEInrRQSDPDRYFVIDPRSGIITLNKALDYEMRKVHELVVQAKDNAS 340
Cdd:cd11304      2 YEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSI--VSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGG 79

                           90
                   ....*....|....*....
gi 1207189697  341 HPEITNAFVTIHVRDYNDN 359
Cdd:cd11304     80 PPLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1858-1955 6.52e-29

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 112.79  E-value: 6.52e-29
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697 1858 SYTVDVSEDAAIGLVVLDATATDVDEGQNGQILYFL-SQEAKGAFTVDPNTGRITTAALLDREKRASYFFQVYAVDLSPa 1936
Cdd:cd11304      1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIvSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGG- 79

                           90
                   ....*....|....*....
gi 1207189697 1937 APRNSTAQVTVTILDVNDN 1955
Cdd:cd11304     80 PPLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2597-2692 4.73e-28

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 110.10  E-value: 4.73e-28
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697 2597 EYIVALSEGAAAGAEILRVTATDPDSAPYAEVQYSISSGDDMKLFSVDQWTGAMKLQRPLDRESQNSHVVIVQASDGHG- 2675
Cdd:cd11304      1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGp 80

                           90
                   ....*....|....*...
gi 1207189697 2676 -RFALAPISVEVKDINDN 2692
Cdd:cd11304     81 pLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2171-2267 1.23e-26

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 106.24  E-value: 1.23e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697 2171 YVTYMHEAQGYDFPIIQVVAEDVDQGQNGQVTYTIESSNQSGLFKIDPQTGSITTTAIMDREIWTQAKLVIKATDRGSPK 2250
Cdd:cd11304      2 YEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPP 81

                           90
                   ....*....|....*..
gi 1207189697 2251 LVGTATITVIIVDLNDN 2267
Cdd:cd11304     82 LSSTATVTITVLDVNDN 98
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1137-1215 2.46e-26

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 104.74  E-value: 2.46e-26
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697  1137 SATDRDAGLNSRLTYRLL--HTDRYFQINSQTGEISTRAALDREHQSSYQLMVVVQDGGTPPRSATGTAHITVLDENDNA 1214
Cdd:smart00112    1 SATDADSGENGKVTYSILsgNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVNDNA 80


                    .
gi 1207189697  1215 P 1215
Cdd:smart00112   81 P 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1567-1646 5.56e-26

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 103.58  E-value: 5.56e-26
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697  1567 AWDADQGENGRVSYRIQSGNTAGRFVLSSNSGSLSILKPLDREEQESYNLTIVAEDHGIPQHSTTQVLSIQVIDVNDEAP 1646
Cdd:smart00112    2 ATDADSGENGKVTYSILSGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVNDNAP 81
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 796-891 1.74e-25

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 102.78  E-value: 1.74e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697  796 QYFFTVSEDVLRGTEVGVVRASSR-NGVSKDVTYTISAGDPDGYFMVDPETGALRTSLPLDHESRPFFDLEIQAR-SGSP 873
Cdd:cd11304      1 SYEVSVPENAPPGTVVLTVSATDPdSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATdGGGP 80

                           90
                   ....*....|....*...
gi 1207189697  874 PAFGDTRVRVTIADVNDN 891
Cdd:cd11304     81 PLSSTATVTITVLDVNDN 98
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 496-578 2.13e-25

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 102.04  E-value: 2.13e-25
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697   496 TARDKDQGPNGDIRYSILPDkkTHSSWFTIDPVTGIITTATKLDYETNPKPSIKVVATDGGRPPLSSTAVVEIDLQDTND 575
Cdd:smart00112    1 SATDADSGENGKVTYSILSG--NDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVND 78


                    ...
gi 1207189697   576 NEP 578
Cdd:smart00112   79 NAP 81
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2480-2589 2.54e-25

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 102.39  E-value: 2.54e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697 2480 EYKATVSEDQLPGATILTLEAVDGDlSQENSGFDFAIASGNVGNAFQIESsvrfieghgfqTVGTLILAERLDFEALSHY 2559
Cdd:cd11304      1 SYEVSVPENAPPGTVVLTVSATDPD-SGENGEVTYSIVSGNEDGLFSIDP-----------STGEITTAKPLDREEQSSY 68

                           90       100       110
                   ....*....|....*....|....*....|
gi 1207189697 2560 NLTVSVSDRGVPQRSSSVPAIITVTDVNDN 2589
Cdd:cd11304     69 TLTVTATDGGGPPLSSTATVTITVLDVNDN 98
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1772-1852 2.80e-25

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 101.66  E-value: 2.80e-25
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697  1772 KATDRDIGESGRLEYKIKAGDPDGDFRLDGSSGALSTSRPLDRERKSSYSLQVVVQDHGSPSLNSTASVEISVLDVNDNS 1851
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVNDNA 80


                    .
gi 1207189697  1852 P 1852
Cdd:smart00112   81 P 81
Cadherin pfam00028
Cadherin domain;
1123-1208 3.76e-25

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 101.61  E-value: 3.76e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697 1123 VRENLPAGTGFGRVSATDRDAGLNSRLTYRLL--HTDRYFQINSQTGEISTRAALDREHQSSYQLMVVVQDGGTPPRSAT 1200
Cdd:pfam00028    5 VPENAPVGTEVLTVTATDPDLGPNGRIFYSILggGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGPPLSST 84


                   ....*...
gi 1207189697 1201 GTAHITVL 1208
Cdd:pfam00028   85 ATVTITVL 92
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1228-1316 1.04e-24

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 100.85  E-value: 1.04e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697 1228 IQVQEGLPAGSLLGTLNAKDPDEGENGTIFYSL-SGSRAERFSLNPNTGELRSSSPLRRAEKAEYSFTITASDRGAPSQS 1306
Cdd:cd11304      4 VSVPENAPPGTVVLTVSATDPDSGENGEVTYSIvSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPPLS 83

                           90
                   ....*....|
gi 1207189697 1307 SSAVLLIQVI 1316
Cdd:cd11304     84 STATVTITVL 93
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1437-1540 1.16e-24

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 100.47  E-value: 1.16e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697 1437 PVTIVIPENTQAGSSVYTFQATDKDgSGPNSEIRYSVQQrwPDNPDLFNLDPVTGVLKLGRELDHEETSSLFLVVQAMDS 1516
Cdd:cd11304      1 SYEVSVPENAPPGTVVLTVSATDPD-SGENGEVTYSIVS--GNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDG 77

                           90       100
                   ....*....|....*....|....
gi 1207189697 1517 AldpNQRLWGSVTARVFVTDENDN 1540
Cdd:cd11304     78 G---GPPLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 375-469 1.86e-24

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 100.08  E-value: 1.86e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697  375 QISEGAQPGQYVARISVSDPDYGEYSNVNVSLEGGD--GKFALttkDSIIYLIYVDQILDREERDSYELRVMATDSGTPP 452
Cdd:cd11304      5 SVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNedGLFSI---DPSTGEITTAKPLDREEQSSYTLTVTATDGGGPP 81

                           90
                   ....*....|....*..
gi 1207189697  453 LHAESSFTIHVTDVNDN 469
Cdd:cd11304     82 LSSTATVTITVLDVNDN 98
Cadherin pfam00028
Cadherin domain;
1653-1741 1.91e-24

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 99.68  E-value: 1.91e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697 1653 FEAQIRENQPAGTSIIQVTASDRDHGTNGLVTY---GGVTEDGFTINAETGVISATRVLDRELQDHYTITVYAKDGGIPP 1729
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYsilGGGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGPP 80

                           90
                   ....*....|..
gi 1207189697 1730 NFAKAKVHITVL 1741
Cdd:pfam00028   81 LSSTATVTITVL 92
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1671-1748 2.11e-24

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 99.35  E-value: 2.11e-24
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697  1671 TASDRDHGTNGLVTY---GGVTEDGFTINAETGVISATRVLDRELQDHYTITVYAKDGGIPPNFAKAKVHITVLDENDNA 1747
Cdd:smart00112    1 SATDADSGENGKVTYsilSGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVNDNA 80


                    .
gi 1207189697  1748 P 1748
Cdd:smart00112   81 P 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 2189-2269 3.04e-23

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 95.88  E-value: 3.04e-23
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697  2189 VAEDVDQGQNGQVTYTIESSNQSGLFKIDPQTGSITTTAIMDREIWTQAKLVIKATDRGSPKLVGTATITVIIVDLNDNS 2268
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVNDNA 80


                    .
gi 1207189697  2269 P 2269
Cdd:smart00112   81 P 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1877-1957 6.12e-23

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 95.11  E-value: 6.12e-23
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697  1877 TATDVDEGQNGQILYFLSQE-AKGAFTVDPNTGRITTAALLDREKRASYFFQVYAVDLSPaAPRNSTAQVTVTILDVNDN 1955
Cdd:smart00112    1 SATDADSGENGKVTYSILSGnDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGG-PPLSSTATVTITVLDVNDN 79


                    ..
gi 1207189697  1956 AP 1957
Cdd:smart00112   80 AP 81
Cadherin pfam00028
Cadherin domain;
1550-1639 9.50e-23

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 94.67  E-value: 9.50e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697 1550 VSVMEDQPVGFVLLYVMAWDADQGENGRVSYRIQSGNTAGRFVLSSNSGSLSILKPLDREEQESYNLTIVAEDHGIPQHS 1629
Cdd:pfam00028    3 ASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGPPLS 82

                           90
                   ....*....|
gi 1207189697 1630 TTQVLSIQVI 1639
Cdd:pfam00028   83 STATVTITVL 92
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 905-995 1.73e-22

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 94.30  E-value: 1.73e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697  905 LPEATKMGTIVYRVQAEDRDSGPNGQLSFDLISSGGQRTFGVERSSGEVRLIGSLSYDSVPRYDLQVIAKDSGAPQLSAT 984
Cdd:cd11304      6 VPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPPLSST 85

                           90
                   ....*....|.
gi 1207189697  985 FSLVVHIQAEN 995
Cdd:cd11304     86 ATVTITVLDVN 96
Cadherin pfam00028
Cadherin domain;
481-571 1.88e-22

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 93.90  E-value: 1.88e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697  481 TIPEVVYPGSFVLQVTARDKDQGPNGDIRYSILPDKKTHssWFTIDPVTGIITTATKLDYETNPKPSIKVVATDGGRPPL 560
Cdd:pfam00028    4 SVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPGG--NFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGPPL 81

                           90
                   ....*....|.
gi 1207189697  561 SSTAVVEIDLQ 571
Cdd:pfam00028   82 SSTATVTITVL 92
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1005-1110 7.72e-22

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 92.38  E-value: 7.72e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697 1005 TYRVELKENTPLNTNFLQVRALNRDPNGNGgsstptsTLAYRLRPDGDAVGFGIAPDSGWLFVKSALDREVKDIYLLTVL 1084
Cdd:cd11304      1 SYEVSVPENAPPGTVVLTVSATDPDSGENG-------EVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVT 73

                           90       100
                   ....*....|....*....|....*.
gi 1207189697 1085 ATSGsGQMGRTGSATIRVSVTDENDN 1110
Cdd:cd11304     74 ATDG-GGPPLSSTATVTITVLDVNDN 98
Cadherin pfam00028
Cadherin domain;
1755-1845 1.11e-21

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 91.98  E-value: 1.11e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697 1755 YSLEVPENLQP-VELFTLKATDRDIGESGRLEYKIKAGDPDGDFRLDGSSGALSTSRPLDRERKSSYSLQVVVQDHGSPS 1833
Cdd:pfam00028    1 YSASVPENAPVgTEVLTVTATDPDLGPNGRIFYSILGGGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGPP 80

                           90
                   ....*....|..
gi 1207189697 1834 LNSTASVEISVL 1845
Cdd:pfam00028   81 LSSTATVTITVL 92
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 280-361 1.42e-21

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 91.26  E-value: 1.42e-21
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697   280 ASDADEGDNGLVLYEINrrQSDPDRYFVIDPRSGIITLNKALDYEMRKVHELVVQAKDNASHPEITNAFVTIHVRDYNDN 359
Cdd:smart00112    2 ATDADSGENGKVTYSIL--SGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVNDN 79


                    ..
gi 1207189697   360 QP 361
Cdd:smart00112   80 AP 81
Cadherin pfam00028
Cadherin domain;
1859-1950 1.73e-20

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 88.51  E-value: 1.73e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697 1859 YTVDVSEDAAIGLVVLDATATDVDEGQNGQILYF-LSQEAKGAFTVDPNTGRITTAALLDREKRASYFFQVYAVDLSPaA 1937
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYSiLGGGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGG-P 79

                           90
                   ....*....|...
gi 1207189697 1938 PRNSTAQVTVTIL 1950
Cdd:pfam00028   80 PLSSTATVTITVL 92
Cadherin pfam00028
Cadherin domain;
1228-1316 3.22e-20

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 87.74  E-value: 3.22e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697 1228 IQVQEGLPAGSLLGTLNAKDPDEGENGTIFYSLSGSRAER-FSLNPNTGELRSSSPLRRAEKAEYSFTITASDRGAPSQS 1306
Cdd:pfam00028    3 ASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPGGnFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGPPLS 82

                           90
                   ....*....|
gi 1207189697 1307 SSAVLLIQVI 1316
Cdd:pfam00028   83 STATVTITVL 92
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 2394-2474 5.10e-20

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 86.63  E-value: 5.10e-20
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697  2394 TATDRDSGENGKVSYRVLSSTRDG-FYVDPKNGTLFIrqKAKFDPEE-PSVSIVIEARDGGSPPLSSSATVQVQLMDVND 2471
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNDDGlFSIDPETGEITT--TKPLDREEqPEYTLTVEATDGGGPPLSSTATVTITVLDVND 78


                    ...
gi 1207189697  2472 NAP 2474
Cdd:smart00112   79 NAP 81
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 585-683 5.46e-20

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 87.37  E-value: 5.46e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697  585 YNVSIKENTSAGTCFLEVKADDADGGSFGTITYSIGSGSvsaPLSQFSINKESGQICTSTALDRdEGADSFHFTVTATDG 664
Cdd:cd11304      2 YEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGN---EDGLFSIDPSTGEITTAKPLDR-EEQSSYTLTVTATDG 77

                           90       100
                   ....*....|....*....|.
gi 1207189697  665 GGLSSSASVLV--SLEDINDN 683
Cdd:cd11304     78 GGPPLSSTATVtiTVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2702-2796 5.52e-20

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 87.37  E-value: 5.52e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697 2702 TASIRENQPLNSAVTVLHAIDYDTGVYGQLKYYLMDHSSPGkdLFFVDQNSGEVRTKQIFDFEKVNSFNFIALAVDAGNN 2781
Cdd:cd11304      3 EVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDG--LFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGP 80

                           90
                   ....*....|....*
gi 1207189697 2782 SATVTVQVFITGEDE 2796
Cdd:cd11304     81 PLSSTATVTITVLDV 95
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 2616-2694 7.59e-20

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 86.25  E-value: 7.59e-20
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697  2616 TATDPDSAPYAEVQYSISSGDDMKLFSVDQWTGAMKLQRPLDRESQNSHVVIVQASDGHG--RFALAPISVEVKDINDNR 2693
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGppLSSTATVTITVLDVNDNA 80


                    .
gi 1207189697  2694 P 2694
Cdd:smart00112   81 P 81
Cadherin pfam00028
Cadherin domain;
2376-2466 1.26e-19

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 85.82  E-value: 1.26e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697 2376 YQVTLPEHSPPGSPVITVTATDRDSGENGKVSYRVLSSTRDG-FYVDPKNGTLFIRQkaKFDPEEPS-VSIVIEARDGGS 2453
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPGGnFRIDPDTGDISTTK--PLDRESIGeYELTVEATDSGG 78

                           90
                   ....*....|...
gi 1207189697 2454 PPLSSSATVQVQL 2466
Cdd:pfam00028   79 PPLSSTATVTITV 91
Cadherin pfam00028
Cadherin domain;
261-353 7.17e-19

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 83.89  E-value: 7.17e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697  261 YNAIISESLPQGSNILQVFASDADEGDNGLVLYEInrRQSDPDRYFVIDPRSGIITLNKALDYEMRKVHELVVQAKDNAS 340
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYSI--LGGGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGG 78

                           90
                   ....*....|...
gi 1207189697  341 HPEITNAFVTIHV 353
Cdd:pfam00028   79 PPLSSTATVTITV 91
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 821-893 1.71e-18

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 82.40  E-value: 1.71e-18
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1207189697   821 GVSKDVTYTISAGDPDGYFMVDPETGALRTSLPLDHESRPFFDLEIQAR-SGSPPAFGDTRVRVTIADVNDNAP 893
Cdd:smart00112    8 GENGKVTYSILSGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATdGGGPPLSSTATVTITVLDVNDNAP 81
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 692-783 2.16e-18

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 82.75  E-value: 2.16e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697  692 YAVSLSTQSSPGTSVIRVTAHDPDAGANGRVTYHTVSGGGSSFFTLNKDTGVISLSRSLHGKANSVIPMVISARDGGGLT 771
Cdd:cd11304      2 YEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPP 81

                           90
                   ....*....|..
gi 1207189697  772 APVNARVNISVV 783
Cdd:cd11304     82 LSSTATVTITVL 93
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 150-252 2.89e-18

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 82.36  E-value: 2.89e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697  150 SLKIPEQTAVGTKFSLEPATDSDKDQLTVQGYQIKEGNVGQVFRLETKraankvlYLDLVVNGVLDREKRSSYSLVVEAF 229
Cdd:cd11304      3 EVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPS-------TGEITTAKPLDREEQSSYTLTVTAT 75

                           90       100
                   ....*....|....*....|...
gi 1207189697  230 DGGSPRQNGQMTLDILVQDINDH 252
Cdd:cd11304     76 DGGGPPLSSTATVTITVLDVNDN 98
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 390-471 3.29e-18

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 81.63  E-value: 3.29e-18
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697   390 SVSDPDYGEYSNVNVSLEGG--DGKFALTTKDSIIYLIyvdQILDREERDSYELRVMATDSGTPPLHAESSFTIHVTDVN 467
Cdd:smart00112    1 SATDADSGENGKVTYSILSGndDGLFSIDPETGEITTT---KPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVN 77


                    ....
gi 1207189697   468 DNPP 471
Cdd:smart00112   78 DNAP 81
Cadherin pfam00028
Cadherin domain;
2598-2686 3.94e-18

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 81.58  E-value: 3.94e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697 2598 YIVALSEGAAAGAEILRVTATDPDSAPYAEVQYSISSGDDMKLFSVDQWTGAMKLQRPLDRESQNSHVVIVQASD--GHG 2675
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDsgGPP 80

                           90
                   ....*....|.
gi 1207189697 2676 RFALAPISVEV 2686
Cdd:pfam00028   81 LSSTATVTITV 91
Cadherin pfam00028
Cadherin domain;
2184-2261 1.00e-17

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 80.42  E-value: 1.00e-17
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1207189697 2184 PIIQVVAEDVDQGQNGQVTYTIESSNQSGLFKIDPQTGSITTTAIMDREIWTQAKLVIKATDRGSPKLVGTATITVII 2261
Cdd:pfam00028   14 EVLTVTATDPDLGPNGRIFYSILGGGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGPPLSSTATVTITV 91
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1456-1542 1.10e-17

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 80.09  E-value: 1.10e-17
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697  1456 QATDKDgSGPNSEIRYSVQQrwPDNPDLFNLDPVTGVLKLGRELDHEETSSLFLVVQAMDSAldpNQRLWGSVTARVFVT 1535
Cdd:smart00112    1 SATDAD-SGENGKVTYSILS--GNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGG---GPPLSSTATVTITVL 74


                    ....*..
gi 1207189697  1536 DENDNAP 1542
Cdd:smart00112   75 DVNDNAP 81
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1336-1429 1.27e-17

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 80.44  E-value: 1.27e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697 1336 EGAKPGSVIGSVRAHDqREVTLNGQVTYLVVGGtDHEGTFMVDRLTGDVYLARELDYEKGSRYTLQIEVDDfSKAYPNTH 1415
Cdd:cd11304      8 ENAPPGTVVLTVSATD-PDSGENGEVTYSIVSG-NEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATD-GGGPPLSS 84

                           90
                   ....*....|....
gi 1207189697 1416 MIQLEINVQDSNDH 1429
Cdd:cd11304     85 TATVTITVLDVNDN 98
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 2500-2591 1.38e-17

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 79.70  E-value: 1.38e-17
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697  2500 AVDGDlSQENSGFDFAIASGNVGNAFQIESSVrfieghgfqtvGTLILAERLDFEALSHYNLTVSVSDRGVPQRSSSVPA 2579
Cdd:smart00112    2 ATDAD-SGENGKVTYSILSGNDDGLFSIDPET-----------GEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATV 69

                            90
                    ....*....|..
gi 1207189697  2580 IITVTDVNDNPP 2591
Cdd:smart00112   70 TITVLDVNDNAP 81
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2274-2358 1.60e-17

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 80.05  E-value: 1.60e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697 2274 PREVRVPENSLIGTEITLVTGNDVDSGP--VLSYSLqLDASTQGKFDIDRYNGRVSLTAPLDYEERTWYKLTIRASDS-- 2349
Cdd:cd11304      1 SYEVSVPENAPPGTVVLTVSATDPDSGEngEVTYSI-VSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGgg 79

                           90
                   ....*....|
gi 1207189697 2350 -KHQSEANLT 2358
Cdd:cd11304     80 pPLSSTATVT 89
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2070-2162 5.10e-17

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 78.89  E-value: 5.10e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697 2070 VSLQENADKGTVVAQAQAQHPDGTRDG-INYSIFSGNKYHSFSISSNTGEIWVQSSngLDFEDTPRLRLVVKAE---TTS 2145
Cdd:cd11304      4 VSVPENAPPGTVVLTVSATDPDSGENGeVTYSIVSGNEDGLFSIDPSTGEITTAKP--LDREEQSSYTLTVTATdggGPP 81

                           90
                   ....*....|....*..
gi 1207189697 2146 SSSFMAVNLILQDVNDN 2162
Cdd:cd11304     82 LSSTATVTITVLDVNDN 98
Cadherin pfam00028
Cadherin domain;
905-992 9.22e-17

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 77.73  E-value: 9.22e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697  905 LPEATKMGTIVYRVQAEDRDSGPNGQLSFDLISSGGQRTFGVERSSGEVRLIGSLSYDSVPRYDLQVIAKDSGAPQLSAT 984
Cdd:pfam00028    5 VPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGPPLSST 84


                   ....*...
gi 1207189697  985 FSLVVHIQ 992
Cdd:pfam00028   85 ATVTITVL 92
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1244-1316 2.19e-16

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 76.23  E-value: 2.19e-16
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1207189697  1244 NAKDPDEGENGTIFYSL-SGSRAERFSLNPNTGELRSSSPLRRAEKAEYSFTITASDRGAPSQSSSAVLLIQVI 1316
Cdd:smart00112    1 SATDADSGENGKVTYSIlSGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVL 74
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 919-999 5.42e-16

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 75.08  E-value: 5.42e-16
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697   919 QAEDRDSGPNGQLSFDLISSGGQRTFGVERSSGEVRLIGSLSYDSVPRYDLQVIAKDSGAPQLSATFSLVVHIQAENNQG 998
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVNDNA 80


                    .
gi 1207189697   999 P 999
Cdd:smart00112   81 P 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 168-254 1.61e-15

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 73.92  E-value: 1.61e-15
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697   168 ATDSDKDQLTVQGYQIKEGNVGQVFRLETKRAAnkvlyldLVVNGVLDREKRSSYSLVVEAFDGGSPRQNGQMTLDILVQ 247
Cdd:smart00112    2 ATDADSGENGKVTYSILSGNDDGLFSIDPETGE-------ITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVL 74


                    ....*..
gi 1207189697   248 DINDHAP 254
Cdd:smart00112   75 DVNDNAP 81
Cadherin pfam00028
Cadherin domain;
2275-2349 1.96e-15

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 73.87  E-value: 1.96e-15
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1207189697 2275 REVRVPENSLIGTEITLVTGNDVDSGP--VLSYSLQLDaSTQGKFDIDRYNGRVSLTAPLDYEERTWYKLTIRASDS 2349
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPngRIFYSILGG-GPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDS 76
Cadherin pfam00028
Cadherin domain;
2481-2584 6.01e-15

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 72.72  E-value: 6.01e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697 2481 YKATVSEDQLPGATILTLEAVDGDLSQeNSGFDFAIASGNVGNAFQIESSVrfieghgfqtvGTLILAERLDFEALSHYN 2560
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGP-NGRIFYSILGGGPGGNFRIDPDT-----------GDISTTKPLDRESIGEYE 68

                           90       100
                   ....*....|....*....|....
gi 1207189697 2561 LTVSVSDRGVPQRSSSVPAIITVT 2584
Cdd:pfam00028   69 LTVEATDSGGPPLSSTATVTITVL 92
Cadherin pfam00028
Cadherin domain;
1006-1105 6.76e-15

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 72.33  E-value: 6.76e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697 1006 YRVELKENTPLNTNFLQVRALNRDpngnggsSTPTSTLAYRLRPDGDAVGFGIAPDSGWLFVKSALDREVKDIYLLTVLA 1085
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPD-------LGPNGRIFYSILGGGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEA 73

                           90       100
                   ....*....|....*....|
gi 1207189697 1086 TSGSGQmGRTGSATIRVSVT 1105
Cdd:pfam00028   74 TDSGGP-PLSSTATVTITVL 92
Cadherin pfam00028
Cadherin domain;
797-885 1.97e-14

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 71.18  E-value: 1.97e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697  797 YFFTVSEDVLRGTEVGVVRASSRN-GVSKDVTYTISAGDPDGYFMVDPETGALRTSLPLDHESRPFFDLEIQAR-SGSPP 874
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDlGPNGRIFYSILGGGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATdSGGPP 80

                           90
                   ....*....|.
gi 1207189697  875 AFGDTRVRVTI 885
Cdd:pfam00028   81 LSSTATVTITV 91
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1041-1112 2.18e-14

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 70.84  E-value: 2.18e-14
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1207189697  1041 STLAYRLRPDGDAVGFGIAPDSGWLFVKSALDREVKDIYLLTVLATSGsGQMGRTGSATIRVSVTDENDNAP 1112
Cdd:smart00112   11 GKVTYSILSGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDG-GGPPLSSTATVTITVLDVNDNAP 81
Cadherin pfam00028
Cadherin domain;
375-464 4.38e-14

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 70.02  E-value: 4.38e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697  375 QISEGAQPGQYVARISVSDPDYGEYSNVNVSLEGG--DGKFALTTKDSIIYLIyvdQILDREERDSYELRVMATDSGTPP 452
Cdd:pfam00028    4 SVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGgpGGNFRIDPDTGDISTT---KPLDRESIGEYELTVEATDSGGPP 80

                           90
                   ....*....|..
gi 1207189697  453 LHAESSFTIHVT 464
Cdd:pfam00028   81 LSSTATVTITVL 92
Cadherin pfam00028
Cadherin domain;
1439-1535 7.86e-14

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 69.64  E-value: 7.86e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697 1439 TIVIPENTQAGSSVYTFQATDKDgSGPNSEIRYSVQQRWPDNpdLFNLDPVTGVLKLGRELDHEETSSLFLVVQAMDSAL 1518
Cdd:pfam00028    2 SASVPENAPVGTEVLTVTATDPD-LGPNGRIFYSILGGGPGG--NFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGG 78

                           90
                   ....*....|....*..
gi 1207189697 1519 DPnqrLWGSVTARVFVT 1535
Cdd:pfam00028   79 PP---LSSTATVTITVL 92
Cadherin pfam00028
Cadherin domain;
2702-2789 1.06e-13

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 69.25  E-value: 1.06e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697 2702 TASIRENQPLNSAVTVLHAIDYDTGVYGQLKYYLMDHSSPGKdlFFVDQNSGEVRTKQIFDFEKVNSFNFIALAVDAGNN 2781
Cdd:pfam00028    2 SASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPGGN--FRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGP 79

                           90
                   ....*....|..
gi 1207189697 2782 S----ATVTVQV 2789
Cdd:pfam00028   80 PlsstATVTITV 91
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 603-685 4.30e-13

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 66.99  E-value: 4.30e-13
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697   603 KADDADGGSFGTITYSIGSGSVSaplSQFSINKESGQICTSTALDRDEGaDSFHFTVTATDGGGLSSSASVLVS--LEDI 680
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNDD---GLFSIDPETGEITTTKPLDREEQ-PEYTLTVEATDGGGPPLSSTATVTitVLDV 76


                    ....*
gi 1207189697   681 NDNRP 685
Cdd:smart00112   77 NDNAP 81
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 50-140 6.54e-13

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 66.95  E-value: 6.54e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697   50 ELQLDEEQPAGTIVGDISA-----GLQPGVTaslYFISDHEGTGIgsdLHIDETTGIIKTARRLDREERDHYSFIAV--- 121
Cdd:cd11304      3 EVSVPENAPPGTVVLTVSAtdpdsGENGEVT---YSIVSGNEDGL---FSIDPSTGEITTAKPLDREEQSSYTLTVTatd 76

                           90       100
                   ....*....|....*....|...
gi 1207189697  122 ----TMTGfTVKVSITVNDINDH 140
Cdd:cd11304     77 gggpPLSS-TATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1977-2054 7.00e-13

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 66.95  E-value: 7.00e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697 1977 QVVATMRAEDKDFGANGSVFYRFA--MPVRGFAINSLTGAIQTTENLQTLTQTQRTLIVEAMDQGSPPQSSLGVVIIYVK 2054
Cdd:cd11304     14 TVVLTVSATDPDSGENGEVTYSIVsgNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPPLSSTATVTITVL 93
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1348-1431 8.11e-13

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 66.22  E-value: 8.11e-13
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697  1348 RAHDQREvTLNGQVTYLVVGGtDHEGTFMVDRLTGDVYLARELDYEKGSRYTLQIEVDDFSKAYPNTHmIQLEINVQDSN 1427
Cdd:smart00112    1 SATDADS-GENGKVTYSILSG-NDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSST-ATVTITVLDVN 77


                    ....
gi 1207189697  1428 DHAP 1431
Cdd:smart00112   78 DNAP 81
Cadherin pfam00028
Cadherin domain;
692-780 1.42e-12

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 65.78  E-value: 1.42e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697  692 YAVSLSTQSSPGTSVIRVTAHDPDAGANGRVTYHTVSGGGSSFFTLNKDTGVISLSRSLHGKANSVIPMVISARDGG--G 769
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGgpP 80

                           90
                   ....*....|.
gi 1207189697  770 LTAPVNARVNI 780
Cdd:pfam00028   81 LSSTATVTITV 91
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2807-2904 5.06e-12

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 64.64  E-value: 5.06e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697 2807 SFEVPEGAKKGQSIGLVQAKDEDGGVDGIVLYSF--PNSSPYFDVNKTTGVIYLK--MDnsgsssggsrskRETR-LMTM 2881
Cdd:cd11304      3 EVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIvsGNEDGLFSIDPSTGEITTAkpLD------------REEQsSYTL 70

                           90       100
                   ....*....|....*....|...
gi 1207189697 2882 DVSAHSPLDTSRVASAQVIIDVT 2904
Cdd:cd11304     71 TVTATDGGGPPLSSTATVTITVL 93
Cadherin pfam00028
Cadherin domain;
153-247 5.89e-12

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 64.24  E-value: 5.89e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697  153 IPEQTAVGTKFSLEPATDSDKDQLTVQGYQIKEGNVGQVFRLETKRAankvlylDLVVNGVLDREKRSSYSLVVEAFDGG 232
Cdd:pfam00028    5 VPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPGGNFRIDPDTG-------DISTTKPLDRESIGEYELTVEATDSG 77

                           90
                   ....*....|....*
gi 1207189697  233 SPRQNGQMTLDILVQ 247
Cdd:pfam00028   78 GPPLSSTATVTITVL 92
Cadherin pfam00028
Cadherin domain;
585-666 7.02e-12

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 63.86  E-value: 7.02e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697  585 YNVSIKENTSAGTCFLEVKADDADGGSFGTITYSIGSGSVSaplSQFSINKESGQICTSTALDRDEGaDSFHFTVTATDG 664
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPG---GNFRIDPDTGDISTTKPLDRESI-GEYELTVEATDS 76


                   ..
gi 1207189697  665 GG 666
Cdd:pfam00028   77 GG 78
Cadherin pfam00028
Cadherin domain;
1336-1406 9.59e-12

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 63.47  E-value: 9.59e-12
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1207189697 1336 EGAKPGSVIGSVRAHDqREVTLNGQVTYLVVGGtDHEGTFMVDRLTGDVYLARELDYEKGSRYTLQIEVDD 1406
Cdd:pfam00028    7 ENAPVGTEVLTVTATD-PDLGPNGRIFYSILGG-GPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATD 75
Cadherin pfam00028
Cadherin domain;
1977-2053 1.09e-11

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 63.47  E-value: 1.09e-11
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1207189697 1977 QVVATMRAEDKDFGANGSVFYRFAMPVRG--FAINSLTGAIQTTENLQTLTQTQRTLIVEAMDQGSPPQSSLGVVIIYV 2053
Cdd:pfam00028   13 TEVLTVTATDPDLGPNGRIFYSILGGGPGgnFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGPPLSSTATVTITV 91
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 710-783 1.56e-11

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 62.37  E-value: 1.56e-11
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1207189697   710 TAHDPDAGANGRVTYHTVSGGGSSFFTLNKDTGVISLSRSLHGKANSVIPMVISARDGGGLTAPVNARVNISVV 783
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVL 74
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 2086-2164 2.88e-11

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 61.60  E-value: 2.88e-11
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697  2086 QAQHPDGTRDG-INYSIFSGNKYHSFSISSNTGEIWVQSSngLDFEDTPRLRLVVKAE---TTSSSSFMAVNLILQDVND 2161
Cdd:smart00112    1 SATDADSGENGkVTYSILSGNDDGLFSIDPETGEITTTKP--LDREEQPEYTLTVEATdggGPPLSSTATVTITVLDVND 78


                    ...
gi 1207189697  2162 NRP 2164
Cdd:smart00112   79 NAP 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 2719-2796 3.54e-11

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 61.60  E-value: 3.54e-11
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1207189697  2719 HAIDYDTGVYGQLKYYLmdHSSPGKDLFFVDQNSGEVRTKQIFDFEKVNSFNFIALAVDAGNNSATVTVQVFITGEDE 2796
Cdd:smart00112    1 SATDADSGENGKVTYSI--LSGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDV 76
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 79-142 2.92e-10

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 58.90  E-value: 2.92e-10
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697    79 YFISDHEGTGIgsdLHIDETTGIIKTARRLDREERDHYSFIAVTMTGF------TVKVSITVNDINDHAP 142
Cdd:smart00112   15 YSILSGNDDGL---FSIDPETGEITTTKPLDREEQPEYTLTVEATDGGgpplssTATVTITVLDVNDNAP 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1983-2057 3.77e-09

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 55.82  E-value: 3.77e-09
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1207189697  1983 RAEDKDFGANGSVFYRFA--MPVRGFAINSLTGAIQTTENLQTLTQTQRTLIVEAMDQGSPPQSSLGVVIIYVKEQD 2057
Cdd:smart00112    1 SATDADSGENGKVTYSILsgNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVN 77
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 2296-2349 1.16e-08

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 54.28  E-value: 1.16e-08
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....*.
gi 1207189697  2296 DVDSGP--VLSYSLqLDASTQGKFDIDRYNGRVSLTAPLDYEERTWYKLTIRASDS 2349
Cdd:smart00112    4 DADSGEngKVTYSI-LSGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDG 58
Cadherin pfam00028
Cadherin domain;
2070-2141 2.04e-08

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 54.23  E-value: 2.04e-08
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1207189697 2070 VSLQENADKGTVVAQAQAQHPD-GTRDGINYSIFSGNKYHSFSISSNTGEIWVQSSngLDFEDTPRLRLVVKA 2141
Cdd:pfam00028    3 ASVPENAPVGTEVLTVTATDPDlGPNGRIFYSILGGGPGGNFRIDPDTGDISTTKP--LDRESIGEYELTVEA 73
Cadherin pfam00028
Cadherin domain;
52-134 1.63e-05

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 45.75  E-value: 1.63e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697   52 QLDEEQPAGTIVG-----DISAGLQPGVTaslYFISdheGTGIGSDLHIDETTGIIKTARRLDREERDHYSFIAVTMTGF 126
Cdd:pfam00028    4 SVPENAPVGTEVLtvtatDPDLGPNGRIF---YSIL---GGGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSG 77

                           90
                   ....*....|....
gi 1207189697  127 ------TVKVSITV 134
Cdd:pfam00028   78 gpplssTATVTITV 91
Cadherin pfam00028
Cadherin domain;
2807-2860 2.44e-05

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 45.37  E-value: 2.44e-05
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1207189697 2807 SFEVPEGAKKGQSIGLVQAKDEDGGVDGIVLYSF--PNSSPYFDVNKTTGVIYLKM 2860
Cdd:pfam00028    2 SASVPENAPVGTEVLTVTATDPDLGPNGRIFYSIlgGGPGGNFRIDPDTGDISTTK 57
CA_like cd00031
Cadherin repeat-like domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1056-1110 1.13e-04

Cadherin repeat-like domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers. This family also includes the cadherin-like repeats of extracellular alpha-dystroglycan.


Pssm-ID: 206635  Cd Length: 98  Bit Score: 43.49  E-value: 1.13e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1207189697 1056 FGIAPDSGWLFVKSALDREVKDIYLLTVLATSGSGQMGRTgSATIRVSVTDENDN 1110
Cdd:cd00031     45 LHWEPHSGILEGLEKLDREDKGVHYISVSAASLGANVPQT-SSVFSIEVYDENDN 98
CA_like cd00031
Cadherin repeat-like domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1859-1955 4.91e-04

Cadherin repeat-like domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers. This family also includes the cadherin-like repeats of extracellular alpha-dystroglycan.


Pssm-ID: 206635  Cd Length: 98  Bit Score: 41.95  E-value: 4.91e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697 1859 YTVDVSEDAAIGLVVLdatATDVDEgQNGQILYFLSQEAK---GAFTVDPNTGRITTAALLDREKRASYFFQVYAVDLSP 1935
Cdd:cd00031      4 GSAVEGRSRGSFRVSI---PTDLIA-SSGEIIKISAAGKEalpSWLHWEPHSGILEGLEKLDREDKGVHYISVSAASLGA 79

                           90       100
                   ....*....|....*....|
gi 1207189697 1936 AAPRNSTaQVTVTILDVNDN 1955
Cdd:cd00031     80 NVPQTSS-VFSIEVYDENDN 98
CA_like cd00031
Cadherin repeat-like domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1759-1850 3.65e-03

Cadherin repeat-like domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers. This family also includes the cadherin-like repeats of extracellular alpha-dystroglycan.


Pssm-ID: 206635  Cd Length: 98  Bit Score: 39.25  E-value: 3.65e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207189697 1759 VPENLQPVELFTLKATDRDiGESGRLeYKIKAG---DPDGDFRLDGSSGALSTSRPLDRERKSSYSLQVVVQDHGSPSLN 1835
Cdd:cd00031      6 AVEGRSRGSFRVSIPTDLI-ASSGEI-IKISAAgkeALPSWLHWEPHSGILEGLEKLDREDKGVHYISVSAASLGANVPQ 83

                           90
                   ....*....|....*
gi 1207189697 1836 STASVEISVLDVNDN 1850
Cdd:cd00031     84 TSSVFSIEVYDENDN 98
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH