|
Name |
Accession |
Description |
Interval |
E-value |
| ADAMTS_spacer1 |
pfam05986 |
ADAM-TS Spacer 1; This domain represents the Spacer-1 region from the ADAM-TS and ADAM-TS-like ... |
173-282 |
1.39e-32 |
|
ADAM-TS Spacer 1; This domain represents the Spacer-1 region from the ADAM-TS and ADAM-TS-like proteins. ADAM-TS (A Disintegrin and Metalloproteinase with Thrombospondin Motifs) is closely related to the ADAM family (A Disintegrin and Metalloproteinase) and is a subfamily of the metalloprotease family, sharing a high degree of sequence similarity and conserved domain organization among its members. Members of the ADAM-TS family have been implicated in a range of diseases. ADAM-TS-like proteins lack a metalloprotease domain. They resides in the ECM and have regulatory roles. Examples of ADAM-TS-like proteins are papilin and punctin.
:
Pssm-ID: 461796 Cd Length: 115 Bit Score: 122.30 E-value: 1.39e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046900346 173 TVSRTFKEAEGMGYVDVGLIPAGAREILIEEVAEAANFLALRSeDPDKYFLNGGWTIQ-WNGDYQVAGTTFTYTRKGN-W 250
Cdd:pfam05986 1 TVSGSFTEGRAKGYVTFVTIPAGATHIHIVNRKPSFTHLAVKN-VQGKYILNGKGSISlNPTYPSLLGTVLEYRRSLPaL 79
|
90 100 110
....*....|....*....|....*....|....*
gi 1046900346 251 ETLTSPGPTTEPVWIQLLFQ---ERNPGVHYKYTI 282
Cdd:pfam05986 80 EELHAPGPTQEDLEIQVLRQygkGTNPGITYEYFI 114
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
991-1046 |
9.80e-14 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
:
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 66.71 E-value: 9.80e-14
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 1046900346 991 WVVGPWGQCSAPCGGGVQRRLVKCVNTqTGLAEEDSDLCSHEAWPESSRPCATEDC 1046
Cdd:pfam19030 1 WVAGPWGECSVTCGGGVQTRLVQCVQK-GGGSIVPDSECSAQKKPPETQSCNLKPC 55
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
297-351 |
1.41e-13 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
:
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 65.94 E-value: 1.41e-13
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 1046900346 297 WHYGPWSKCPVTCGTGVQRQSLYCMEKQAGIVDEGH-CDHLSRPRDRKRkCNEEPC 351
Cdd:pfam19030 1 WVAGPWGECSVTCGGGVQTRLVQCVQKGGGSIVPDSeCSAQKKPPETQS-CNLKPC 55
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
884-939 |
9.95e-12 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
:
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 60.93 E-value: 9.95e-12
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 1046900346 884 WRAGNWSKCSRNCGGGSATRDVQCVDTRDLRPLRPFHCqPGPTKPPTRQLCGTQPC 939
Cdd:pfam19030 1 WVAGPWGECSVTCGGGVQTRLVQCVQKGGGSIVPDSEC-SAQKKPPETQSCNLKPC 55
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
833-881 |
6.04e-10 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
:
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 55.92 E-value: 6.04e-10
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 1046900346 833 WQVGNWSQCSTTCGLGAIWRLVRCSSG------NDEDCTLSSRPQPARHCHLRPC 881
Cdd:pfam19030 1 WVAGPWGECSVTCGGGVQTRLVQCVQKgggsivPDSECSAQKKPPETQSCNLKPC 55
|
|
| PHA03247 super family |
cl33720 |
large tegument protein UL36; Provisional |
527-821 |
1.02e-08 |
|
large tegument protein UL36; Provisional
The actual alignment was detected with superfamily member PHA03247:
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 59.95 E-value: 1.02e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046900346 527 PPHIRPTEPPSDSPVPTAGAPGAEEEGIQGSWSPSPllseasHSPPVLLENTPVNPLANFLTEEESPIGAPELGLPSVSW 606
Cdd:PHA03247 2771 PPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPAD------PPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPG 2844
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046900346 607 PPASVDGMVTSVAPGNPdeLLVREDTQSQPSTPWSDRN----KLSKDGNPLGPTSPALPKSPF--PTQPSSPSNSTTQAS 680
Cdd:PHA03247 2845 PPPPSLPLGGSVAPGGD--VRRRPPSRSPAAKPAAPARppvrRLARPAVSRSTESFALPPDQPerPPQPQAPPPPQPQPQ 2922
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046900346 681 LSPDAVEVSTGWNVALDPVLEADLKPVHGELRPTVEMASPPLPSMA--TVPGVWGRESPLEPG--TSTSSTPGLSSQNLK 756
Cdd:PHA03247 2923 PPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVpgRVAVPRFRVPQPAPSreAPASSTPPLTGHSLS 3002
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1046900346 757 TLTVPGTFL-LTAPTDPGLLDQIQTPH----TEGTQS-------PGLLPRPAQETQTNSSKDPAVQPLQPSLVEDGA 821
Cdd:PHA03247 3003 RVSSWASSLaLHEETDPPPVSLKQTLWppddTEDSDAdslfdsdSERSDLEALDPLPPEPHDPFAHEPDPATPEAGA 3079
|
|
| ADAMTS_CR_3 super family |
cl41950 |
ADAMTS cysteine-rich domain; This cysteine rich domain is found in a variety of ADAMTS and ... |
73-171 |
3.27e-08 |
|
ADAMTS cysteine-rich domain; This cysteine rich domain is found in a variety of ADAMTS and ADAMTS-like endopeptidases widely spread in animals. It is a well-conserved cysteine-rich sequence containing 10 cysteine residues. ADAM-TS (A Disintegrin and Metalloproteinase with Thrombospondin Motifs) is closely related to the ADAM family (A Disintegrin and Metalloproteinase, pfam08516) and consists of at least 20 members sharing a high degree of sequence similarity and conserved domain organization. Members of the ADAMTS family have been implicated in a range of diseases.
The actual alignment was detected with superfamily member pfam19236:
Pssm-ID: 437068 Cd Length: 115 Bit Score: 52.79 E-value: 3.27e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046900346 73 FRHTQCSQFDSMLYK-----GKLHKW---VPVLNDENPCELHCRPFNYSNREKLRDAVMDGTPCYQGRISRD----ICID 140
Cdd:pfam19236 5 FMSQQCARTDGQPLRsspggASFYHWgaaVPHSQGDALCRHMCRAIGESFIMKRGDSFLDGTRCMPSGPREDgtlsLCVL 84
|
90 100 110
....*....|....*....|....*....|.
gi 1046900346 141 GICKKVGCDFELDSGAEEDRCGVCRGDGSTC 171
Cdd:pfam19236 85 GSCRTFGCDGRMDSQQVWDRCQVCGGDNSTC 115
|
|
| TSP1_ADAMTS super family |
cl40597 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
942-988 |
6.20e-08 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
The actual alignment was detected with superfamily member pfam19030:
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 50.14 E-value: 6.20e-08
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 1046900346 942 WYTSSWRECSEACGGGEQQRLVTCPEPG--------LCEESLRPNNTRPCNTHPC 988
Cdd:pfam19030 1 WVAGPWGECSVTCGGGVQTRLVQCVQKGggsivpdsECSAQKKPPETQSCNLKPC 55
|
|
| TSP1_ADAMTS super family |
cl40597 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
355-408 |
1.24e-07 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
The actual alignment was detected with superfamily member pfam19030:
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 49.37 E-value: 1.24e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 1046900346 355 WWVGDWQPCSRSCGpGGFFRRAVFCTRSVGLDEQRalePSACGHLPRPLAEIPC 408
Cdd:pfam19030 1 WVAGPWGECSVTCG-GGVQTRLVQCVQKGGGSIVP---DSECSAQKKPPETQSC 50
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| ADAMTS_spacer1 |
pfam05986 |
ADAM-TS Spacer 1; This domain represents the Spacer-1 region from the ADAM-TS and ADAM-TS-like ... |
173-282 |
1.39e-32 |
|
ADAM-TS Spacer 1; This domain represents the Spacer-1 region from the ADAM-TS and ADAM-TS-like proteins. ADAM-TS (A Disintegrin and Metalloproteinase with Thrombospondin Motifs) is closely related to the ADAM family (A Disintegrin and Metalloproteinase) and is a subfamily of the metalloprotease family, sharing a high degree of sequence similarity and conserved domain organization among its members. Members of the ADAM-TS family have been implicated in a range of diseases. ADAM-TS-like proteins lack a metalloprotease domain. They resides in the ECM and have regulatory roles. Examples of ADAM-TS-like proteins are papilin and punctin.
Pssm-ID: 461796 Cd Length: 115 Bit Score: 122.30 E-value: 1.39e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046900346 173 TVSRTFKEAEGMGYVDVGLIPAGAREILIEEVAEAANFLALRSeDPDKYFLNGGWTIQ-WNGDYQVAGTTFTYTRKGN-W 250
Cdd:pfam05986 1 TVSGSFTEGRAKGYVTFVTIPAGATHIHIVNRKPSFTHLAVKN-VQGKYILNGKGSISlNPTYPSLLGTVLEYRRSLPaL 79
|
90 100 110
....*....|....*....|....*....|....*
gi 1046900346 251 ETLTSPGPTTEPVWIQLLFQ---ERNPGVHYKYTI 282
Cdd:pfam05986 80 EELHAPGPTQEDLEIQVLRQygkGTNPGITYEYFI 114
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
991-1046 |
9.80e-14 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 66.71 E-value: 9.80e-14
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 1046900346 991 WVVGPWGQCSAPCGGGVQRRLVKCVNTqTGLAEEDSDLCSHEAWPESSRPCATEDC 1046
Cdd:pfam19030 1 WVAGPWGECSVTCGGGVQTRLVQCVQK-GGGSIVPDSECSAQKKPPETQSCNLKPC 55
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
297-351 |
1.41e-13 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 65.94 E-value: 1.41e-13
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 1046900346 297 WHYGPWSKCPVTCGTGVQRQSLYCMEKQAGIVDEGH-CDHLSRPRDRKRkCNEEPC 351
Cdd:pfam19030 1 WVAGPWGECSVTCGGGVQTRLVQCVQKGGGSIVPDSeCSAQKKPPETQS-CNLKPC 55
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
884-939 |
9.95e-12 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 60.93 E-value: 9.95e-12
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 1046900346 884 WRAGNWSKCSRNCGGGSATRDVQCVDTRDLRPLRPFHCqPGPTKPPTRQLCGTQPC 939
Cdd:pfam19030 1 WVAGPWGECSVTCGGGVQTRLVQCVQKGGGSIVPDSEC-SAQKKPPETQSCNLKPC 55
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
833-881 |
6.04e-10 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 55.92 E-value: 6.04e-10
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 1046900346 833 WQVGNWSQCSTTCGLGAIWRLVRCSSG------NDEDCTLSSRPQPARHCHLRPC 881
Cdd:pfam19030 1 WVAGPWGECSVTCGGGVQTRLVQCVQKgggsivPDSECSAQKKPPETQSCNLKPC 55
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
527-821 |
1.02e-08 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 59.95 E-value: 1.02e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046900346 527 PPHIRPTEPPSDSPVPTAGAPGAEEEGIQGSWSPSPllseasHSPPVLLENTPVNPLANFLTEEESPIGAPELGLPSVSW 606
Cdd:PHA03247 2771 PPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPAD------PPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPG 2844
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046900346 607 PPASVDGMVTSVAPGNPdeLLVREDTQSQPSTPWSDRN----KLSKDGNPLGPTSPALPKSPF--PTQPSSPSNSTTQAS 680
Cdd:PHA03247 2845 PPPPSLPLGGSVAPGGD--VRRRPPSRSPAAKPAAPARppvrRLARPAVSRSTESFALPPDQPerPPQPQAPPPPQPQPQ 2922
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046900346 681 LSPDAVEVSTGWNVALDPVLEADLKPVHGELRPTVEMASPPLPSMA--TVPGVWGRESPLEPG--TSTSSTPGLSSQNLK 756
Cdd:PHA03247 2923 PPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVpgRVAVPRFRVPQPAPSreAPASSTPPLTGHSLS 3002
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1046900346 757 TLTVPGTFL-LTAPTDPGLLDQIQTPH----TEGTQS-------PGLLPRPAQETQTNSSKDPAVQPLQPSLVEDGA 821
Cdd:PHA03247 3003 RVSSWASSLaLHEETDPPPVSLKQTLWppddTEDSDAdslfdsdSERSDLEALDPLPPEPHDPFAHEPDPATPEAGA 3079
|
|
| ADAMTS_CR_3 |
pfam19236 |
ADAMTS cysteine-rich domain; This cysteine rich domain is found in a variety of ADAMTS and ... |
73-171 |
3.27e-08 |
|
ADAMTS cysteine-rich domain; This cysteine rich domain is found in a variety of ADAMTS and ADAMTS-like endopeptidases widely spread in animals. It is a well-conserved cysteine-rich sequence containing 10 cysteine residues. ADAM-TS (A Disintegrin and Metalloproteinase with Thrombospondin Motifs) is closely related to the ADAM family (A Disintegrin and Metalloproteinase, pfam08516) and consists of at least 20 members sharing a high degree of sequence similarity and conserved domain organization. Members of the ADAMTS family have been implicated in a range of diseases.
Pssm-ID: 437068 Cd Length: 115 Bit Score: 52.79 E-value: 3.27e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046900346 73 FRHTQCSQFDSMLYK-----GKLHKW---VPVLNDENPCELHCRPFNYSNREKLRDAVMDGTPCYQGRISRD----ICID 140
Cdd:pfam19236 5 FMSQQCARTDGQPLRsspggASFYHWgaaVPHSQGDALCRHMCRAIGESFIMKRGDSFLDGTRCMPSGPREDgtlsLCVL 84
|
90 100 110
....*....|....*....|....*....|.
gi 1046900346 141 GICKKVGCDFELDSGAEEDRCGVCRGDGSTC 171
Cdd:pfam19236 85 GSCRTFGCDGRMDSQQVWDRCQVCGGDNSTC 115
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
942-988 |
6.20e-08 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 50.14 E-value: 6.20e-08
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 1046900346 942 WYTSSWRECSEACGGGEQQRLVTCPEPG--------LCEESLRPNNTRPCNTHPC 988
Cdd:pfam19030 1 WVAGPWGECSVTCGGGVQTRLVQCVQKGggsivpdsECSAQKKPPETQSCNLKPC 55
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
355-408 |
1.24e-07 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 49.37 E-value: 1.24e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 1046900346 355 WWVGDWQPCSRSCGpGGFFRRAVFCTRSVGLDEQRalePSACGHLPRPLAEIPC 408
Cdd:pfam19030 1 WVAGPWGECSVTCG-GGVQTRLVQCVQKGGGSIVP---DSECSAQKKPPETQSC 50
|
|
| TSP1 |
smart00209 |
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta. |
297-352 |
1.09e-05 |
|
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
Pssm-ID: 214559 [Multi-domain] Cd Length: 53 Bit Score: 43.73 E-value: 1.09e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 1046900346 297 WHYGPWSKCPVTCGTGVQRQSLYCmEKQAGIVDEGHCDHlsrPRDRKRKCNEEPCP 352
Cdd:smart00209 2 SEWSEWSPCSVTCGGGVQTRTRSC-CSPPPQNGGGPCTG---EDVETRACNEQPCP 53
|
|
| TSP1 |
smart00209 |
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta. |
988-1047 |
9.89e-05 |
|
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
Pssm-ID: 214559 [Multi-domain] Cd Length: 53 Bit Score: 41.03 E-value: 9.89e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046900346 988 CTQWvvGPWGQCSAPCGGGVQRRLVKCVNtqtGLAEEDSDLCSHEAwpESSRPCATEDCE 1047
Cdd:smart00209 1 WSEW--SEWSPCSVTCGGGVQTRTRSCCS---PPPQNGGGPCTGED--VETRACNEQPCP 53
|
|
| Herpes_BLLF1 |
pfam05109 |
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ... |
522-805 |
6.35e-04 |
|
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.
Pssm-ID: 282904 [Multi-domain] Cd Length: 886 Bit Score: 44.14 E-value: 6.35e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046900346 522 GGQTVPPHIRPTEPPSDSPVPTAGAP-GAEEEGIQGSWSPSPLLSEAS--HSPPVLLENTPVNPLANFLTEEESPIGAPE 598
Cdd:pfam05109 484 GASPVTPSPSPRDNGTESKAPDMTSPtSAVTTPTPNATSPTPAVTTPTpnATSPTLGKTSPTSAVTTPTPNATSPTPAVT 563
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046900346 599 LGLPSVSWPPASVDGMVTSVAPGNPDEllvrEDTQSQPSTPWSDRNKLSKDGNPLGPTSPALPKSPFPT----QPSSPSN 674
Cdd:pfam05109 564 TPTPNATIPTLGKTSPTSAVTTPTPNA----TSPTVGETSPQANTTNHTLGGTSSTPVVTSPPKNATSAvttgQHNITSS 639
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046900346 675 STTQASLSPDAVE----VSTGWNVALDPVLEADLKPVHGELRPTVEMASPPLPSMATvpgvwGRESPLEPGTSTSSTPGL 750
Cdd:pfam05109 640 STSSMSLRPSSISetlsPSTSDNSTSHMPLLTSAHPTGGENITQVTPASTSTHHVST-----SSPAPRPGTTSQASGPGN 714
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*
gi 1046900346 751 SSqnlkTLTVPGTFLLTAPTDPGLLDQIQTPHTEGTQSPGLLPRPAQETQTNSSK 805
Cdd:pfam05109 715 SS----TSTKPGEVNVTKGTPPKNATSPQAPSGQKTAVPTVTSTGGKANSTTGGK 765
|
|
| TSP1 |
smart00209 |
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta. |
944-988 |
7.31e-03 |
|
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
Pssm-ID: 214559 [Multi-domain] Cd Length: 53 Bit Score: 35.64 E-value: 7.31e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 1046900346 944 TSSWRECSEACGGGEQQRLVTC--PEPGLCEESLRPNN--TRPCNTHPC 988
Cdd:smart00209 4 WSEWSPCSVTCGGGVQTRTRSCcsPPPQNGGGPCTGEDveTRACNEQPC 52
|
|
| TSP1 |
smart00209 |
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta. |
887-939 |
7.39e-03 |
|
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
Pssm-ID: 214559 [Multi-domain] Cd Length: 53 Bit Score: 35.64 E-value: 7.39e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 1046900346 887 GNWSKCSRNCGGGSATRDVQCVDtrdlrPLRPFHCQPGPTKPPTRQLCGTQPC 939
Cdd:smart00209 5 SEWSPCSVTCGGGVQTRTRSCCS-----PPPQNGGGPCTGEDVETRACNEQPC 52
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| ADAMTS_spacer1 |
pfam05986 |
ADAM-TS Spacer 1; This domain represents the Spacer-1 region from the ADAM-TS and ADAM-TS-like ... |
173-282 |
1.39e-32 |
|
ADAM-TS Spacer 1; This domain represents the Spacer-1 region from the ADAM-TS and ADAM-TS-like proteins. ADAM-TS (A Disintegrin and Metalloproteinase with Thrombospondin Motifs) is closely related to the ADAM family (A Disintegrin and Metalloproteinase) and is a subfamily of the metalloprotease family, sharing a high degree of sequence similarity and conserved domain organization among its members. Members of the ADAM-TS family have been implicated in a range of diseases. ADAM-TS-like proteins lack a metalloprotease domain. They resides in the ECM and have regulatory roles. Examples of ADAM-TS-like proteins are papilin and punctin.
Pssm-ID: 461796 Cd Length: 115 Bit Score: 122.30 E-value: 1.39e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046900346 173 TVSRTFKEAEGMGYVDVGLIPAGAREILIEEVAEAANFLALRSeDPDKYFLNGGWTIQ-WNGDYQVAGTTFTYTRKGN-W 250
Cdd:pfam05986 1 TVSGSFTEGRAKGYVTFVTIPAGATHIHIVNRKPSFTHLAVKN-VQGKYILNGKGSISlNPTYPSLLGTVLEYRRSLPaL 79
|
90 100 110
....*....|....*....|....*....|....*
gi 1046900346 251 ETLTSPGPTTEPVWIQLLFQ---ERNPGVHYKYTI 282
Cdd:pfam05986 80 EELHAPGPTQEDLEIQVLRQygkGTNPGITYEYFI 114
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
991-1046 |
9.80e-14 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 66.71 E-value: 9.80e-14
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 1046900346 991 WVVGPWGQCSAPCGGGVQRRLVKCVNTqTGLAEEDSDLCSHEAWPESSRPCATEDC 1046
Cdd:pfam19030 1 WVAGPWGECSVTCGGGVQTRLVQCVQK-GGGSIVPDSECSAQKKPPETQSCNLKPC 55
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
297-351 |
1.41e-13 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 65.94 E-value: 1.41e-13
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 1046900346 297 WHYGPWSKCPVTCGTGVQRQSLYCMEKQAGIVDEGH-CDHLSRPRDRKRkCNEEPC 351
Cdd:pfam19030 1 WVAGPWGECSVTCGGGVQTRLVQCVQKGGGSIVPDSeCSAQKKPPETQS-CNLKPC 55
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
884-939 |
9.95e-12 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 60.93 E-value: 9.95e-12
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 1046900346 884 WRAGNWSKCSRNCGGGSATRDVQCVDTRDLRPLRPFHCqPGPTKPPTRQLCGTQPC 939
Cdd:pfam19030 1 WVAGPWGECSVTCGGGVQTRLVQCVQKGGGSIVPDSEC-SAQKKPPETQSCNLKPC 55
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
833-881 |
6.04e-10 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 55.92 E-value: 6.04e-10
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 1046900346 833 WQVGNWSQCSTTCGLGAIWRLVRCSSG------NDEDCTLSSRPQPARHCHLRPC 881
Cdd:pfam19030 1 WVAGPWGECSVTCGGGVQTRLVQCVQKgggsivPDSECSAQKKPPETQSCNLKPC 55
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
527-821 |
1.02e-08 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 59.95 E-value: 1.02e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046900346 527 PPHIRPTEPPSDSPVPTAGAPGAEEEGIQGSWSPSPllseasHSPPVLLENTPVNPLANFLTEEESPIGAPELGLPSVSW 606
Cdd:PHA03247 2771 PPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPAD------PPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPG 2844
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046900346 607 PPASVDGMVTSVAPGNPdeLLVREDTQSQPSTPWSDRN----KLSKDGNPLGPTSPALPKSPF--PTQPSSPSNSTTQAS 680
Cdd:PHA03247 2845 PPPPSLPLGGSVAPGGD--VRRRPPSRSPAAKPAAPARppvrRLARPAVSRSTESFALPPDQPerPPQPQAPPPPQPQPQ 2922
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046900346 681 LSPDAVEVSTGWNVALDPVLEADLKPVHGELRPTVEMASPPLPSMA--TVPGVWGRESPLEPG--TSTSSTPGLSSQNLK 756
Cdd:PHA03247 2923 PPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVpgRVAVPRFRVPQPAPSreAPASSTPPLTGHSLS 3002
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1046900346 757 TLTVPGTFL-LTAPTDPGLLDQIQTPH----TEGTQS-------PGLLPRPAQETQTNSSKDPAVQPLQPSLVEDGA 821
Cdd:PHA03247 3003 RVSSWASSLaLHEETDPPPVSLKQTLWppddTEDSDAdslfdsdSERSDLEALDPLPPEPHDPFAHEPDPATPEAGA 3079
|
|
| ADAMTS_CR_3 |
pfam19236 |
ADAMTS cysteine-rich domain; This cysteine rich domain is found in a variety of ADAMTS and ... |
73-171 |
3.27e-08 |
|
ADAMTS cysteine-rich domain; This cysteine rich domain is found in a variety of ADAMTS and ADAMTS-like endopeptidases widely spread in animals. It is a well-conserved cysteine-rich sequence containing 10 cysteine residues. ADAM-TS (A Disintegrin and Metalloproteinase with Thrombospondin Motifs) is closely related to the ADAM family (A Disintegrin and Metalloproteinase, pfam08516) and consists of at least 20 members sharing a high degree of sequence similarity and conserved domain organization. Members of the ADAMTS family have been implicated in a range of diseases.
Pssm-ID: 437068 Cd Length: 115 Bit Score: 52.79 E-value: 3.27e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046900346 73 FRHTQCSQFDSMLYK-----GKLHKW---VPVLNDENPCELHCRPFNYSNREKLRDAVMDGTPCYQGRISRD----ICID 140
Cdd:pfam19236 5 FMSQQCARTDGQPLRsspggASFYHWgaaVPHSQGDALCRHMCRAIGESFIMKRGDSFLDGTRCMPSGPREDgtlsLCVL 84
|
90 100 110
....*....|....*....|....*....|.
gi 1046900346 141 GICKKVGCDFELDSGAEEDRCGVCRGDGSTC 171
Cdd:pfam19236 85 GSCRTFGCDGRMDSQQVWDRCQVCGGDNSTC 115
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
942-988 |
6.20e-08 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 50.14 E-value: 6.20e-08
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 1046900346 942 WYTSSWRECSEACGGGEQQRLVTCPEPG--------LCEESLRPNNTRPCNTHPC 988
Cdd:pfam19030 1 WVAGPWGECSVTCGGGVQTRLVQCVQKGggsivpdsECSAQKKPPETQSCNLKPC 55
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
355-408 |
1.24e-07 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 49.37 E-value: 1.24e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 1046900346 355 WWVGDWQPCSRSCGpGGFFRRAVFCTRSVGLDEQRalePSACGHLPRPLAEIPC 408
Cdd:pfam19030 1 WVAGPWGECSVTCG-GGVQTRLVQCVQKGGGSIVP---DSECSAQKKPPETQSC 50
|
|
| TSP1 |
smart00209 |
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta. |
297-352 |
1.09e-05 |
|
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
Pssm-ID: 214559 [Multi-domain] Cd Length: 53 Bit Score: 43.73 E-value: 1.09e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 1046900346 297 WHYGPWSKCPVTCGTGVQRQSLYCmEKQAGIVDEGHCDHlsrPRDRKRKCNEEPCP 352
Cdd:smart00209 2 SEWSEWSPCSVTCGGGVQTRTRSC-CSPPPQNGGGPCTG---EDVETRACNEQPCP 53
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
514-828 |
1.80e-05 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 49.17 E-value: 1.80e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046900346 514 SHSDLVDIGGQTVPPHIRPTEPPSDSPVPTAGAPGaeeegiqGSWSPSPLLSEASHSPPV-----LLENTPVNPLANFLT 588
Cdd:PHA03247 2694 SLTSLADPPPPPPTPEPAPHALVSATPLPPGPAAA-------RQASPALPAAPAPPAVPAgpatpGGPARPARPPTTAGP 2766
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046900346 589 EEESPIGAPELGLPSVSWPPASVDGMV-TSVAPGNPDEllvrEDTQSQPSTPWSDRNKLSKDGNPLGPTSPALPKSPFPT 667
Cdd:PHA03247 2767 PAPAPPAAPAAGPPRRLTRPAVASLSEsRESLPSPWDP----ADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPP 2842
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046900346 668 QPSSPSNSTTQASLSPdavevstGWNVALDPVLEADLKPVHGELRPTVEMASPPLPSMATVPGVWGRESPLEPGTSTSST 747
Cdd:PHA03247 2843 PGPPPPSLPLGGSVAP-------GGDVRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPP 2915
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046900346 748 PGLSSQNLKTLTVPGtfllTAPTDPGLLDQIQTPHTEGTQSPGllPRPAQETQTNSSKDPAVQPLQPSLVEDGAPTDLLP 827
Cdd:PHA03247 2916 PPQPQPQPPPPPQPQ----PPPPPPPRPQPPLAPTTDPAGAGE--PSGAVPQPWLGALVPGRVAVPRFRVPQPAPSREAP 2989
|
.
gi 1046900346 828 A 828
Cdd:PHA03247 2990 A 2990
|
|
| TSP1 |
smart00209 |
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta. |
988-1047 |
9.89e-05 |
|
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
Pssm-ID: 214559 [Multi-domain] Cd Length: 53 Bit Score: 41.03 E-value: 9.89e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046900346 988 CTQWvvGPWGQCSAPCGGGVQRRLVKCVNtqtGLAEEDSDLCSHEAwpESSRPCATEDCE 1047
Cdd:smart00209 1 WSEW--SEWSPCSVTCGGGVQTRTRSCCS---PPPQNGGGPCTGED--VETRACNEQPCP 53
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
452-828 |
1.27e-04 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 46.47 E-value: 1.27e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046900346 452 DPHQPVPRPSPASSPKPvsisnaideEDPELDPPGPvfvddfyydynfinfhedlsygSFEESHSDLVDIGGQTVPPHIR 531
Cdd:PHA03247 2603 DDRGDPRGPAPPSPLPP---------DTHAPDPPPP----------------------SPSPAANEPDPHPPPTVPPPER 2651
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046900346 532 PTEPPSDSPVPTAGAPGAEEEGIQGSwSPSPLLSEASHSPPVllenTPVNPLANFLTEEESPIGAPELGLPSVSWPPASV 611
Cdd:PHA03247 2652 PRDDPAPGRVSRPRRARRLGRAAQAS-SPPQRPRRRAARPTV----GSLTSLADPPPPPPTPEPAPHALVSATPLPPGPA 2726
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046900346 612 DGMVTSVA-PGNPdellVREDTQSQPSTPWSDRNKLSKdGNPLGPTSPALPKSPfPTQPSSPSNSTTQASLSPDAVEVST 690
Cdd:PHA03247 2727 AARQASPAlPAAP----APPAVPAGPATPGGPARPARP-PTTAGPPAPAPPAAP-AAGPPRRLTRPAVASLSESRESLPS 2800
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046900346 691 GWnvalDPVLEADLKPVHGELRPTVEMASPPLPSMATVPGVwgrESPLEPGTSTSSTPglssqnLKTLTVP-GTFLLTAP 769
Cdd:PHA03247 2801 PW----DPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPT---APPPPPGPPPPSLP------LGGSVAPgGDVRRRPP 2867
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1046900346 770 TDPglldQIQTPHTEGTQSPGLLPRPAQETQTNS---SKDPAVQPLQPSLVEDGAPTDLLPA 828
Cdd:PHA03247 2868 SRS----PAAKPAAPARPPVRRLARPAVSRSTESfalPPDQPERPPQPQAPPPPQPQPQPPP 2925
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
517-831 |
5.78e-04 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 44.16 E-value: 5.78e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046900346 517 DLVDIGGQTVPPHIRPTEPPSD-SPVPTAGAPGAEEEGIQGSWSPSPllseASHSPPVLLENTPVNP------LANFLTE 589
Cdd:PHA03247 2465 SLSLLLGELFPGAPVYRRPAEArFPFAAGAAPDPGGGGPPDPDAPPA----PSRLAPAILPDEPVGEpvhprmLTWIRGL 2540
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046900346 590 EE---SPIGAPELGLPSVSWPPASVDGMVTSVAPGNPDELLV--REDTQSQPSTPWSDRNKLSKDGNPLGPTSPAlPKSP 664
Cdd:PHA03247 2541 EElasDDAGDPPPPLPPAAPPAAPDRSVPPPRPAPRPSEPAVtsRARRPDAPPQSARPRAPVDDRGDPRGPAPPS-PLPP 2619
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046900346 665 FPTQPSSPSNSTtqaslSPDAVEVSTGWNVALDPVLEADLKPVHGELRPTVEMASPPLPSMATVPGV-WGRES------- 736
Cdd:PHA03247 2620 DTHAPDPPPPSP-----SPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQrPRRRAarptvgs 2694
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046900346 737 ------PLEPGTSTSSTPGLSSQNLKTLTVPGTFLLTAPTDPglLDQIQTPHTEGTQSPGLLPRPAQETQTNSSKDP--- 807
Cdd:PHA03247 2695 ltsladPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALP--AAPAPPAVPAGPATPGGPARPARPPTTAGPPAPapp 2772
|
330 340 350
....*....|....*....|....*....|....*...
gi 1046900346 808 --------------AVQPLQPSLVEDGAPTDLLPAKNA 831
Cdd:PHA03247 2773 aapaagpprrltrpAVASLSESRESLPSPWDPADPPAA 2810
|
|
| Herpes_BLLF1 |
pfam05109 |
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ... |
522-805 |
6.35e-04 |
|
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.
Pssm-ID: 282904 [Multi-domain] Cd Length: 886 Bit Score: 44.14 E-value: 6.35e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046900346 522 GGQTVPPHIRPTEPPSDSPVPTAGAP-GAEEEGIQGSWSPSPLLSEAS--HSPPVLLENTPVNPLANFLTEEESPIGAPE 598
Cdd:pfam05109 484 GASPVTPSPSPRDNGTESKAPDMTSPtSAVTTPTPNATSPTPAVTTPTpnATSPTLGKTSPTSAVTTPTPNATSPTPAVT 563
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046900346 599 LGLPSVSWPPASVDGMVTSVAPGNPDEllvrEDTQSQPSTPWSDRNKLSKDGNPLGPTSPALPKSPFPT----QPSSPSN 674
Cdd:pfam05109 564 TPTPNATIPTLGKTSPTSAVTTPTPNA----TSPTVGETSPQANTTNHTLGGTSSTPVVTSPPKNATSAvttgQHNITSS 639
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046900346 675 STTQASLSPDAVE----VSTGWNVALDPVLEADLKPVHGELRPTVEMASPPLPSMATvpgvwGRESPLEPGTSTSSTPGL 750
Cdd:pfam05109 640 STSSMSLRPSSISetlsPSTSDNSTSHMPLLTSAHPTGGENITQVTPASTSTHHVST-----SSPAPRPGTTSQASGPGN 714
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*
gi 1046900346 751 SSqnlkTLTVPGTFLLTAPTDPGLLDQIQTPHTEGTQSPGLLPRPAQETQTNSSK 805
Cdd:pfam05109 715 SS----TSTKPGEVNVTKGTPPKNATSPQAPSGQKTAVPTVTSTGGKANSTTGGK 765
|
|
| TSP1_spondin |
pfam19028 |
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an ... |
941-988 |
5.03e-03 |
|
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an alternative disulphide binding pattern compared to the canonical TSP1 domain.
Pssm-ID: 465948 Cd Length: 52 Bit Score: 36.10 E-value: 5.03e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 1046900346 941 PWytSSWRECSEACGGGEQQR---LVTCPEPG--LCEESLRpnnTRPCNTHPC 988
Cdd:pfam19028 5 EW--SEWSECSVTCGGGVQTRtrtVIVEPQNGgrPCPELLE---RRPCNLPPC 52
|
|
| TSP1_CCN |
pfam19035 |
CCN3 Nov like TSP1 domain; This entry represents a sub-type of TSP1 domains found in ... |
834-881 |
6.98e-03 |
|
CCN3 Nov like TSP1 domain; This entry represents a sub-type of TSP1 domains found in matricellular CCN proteins that have an alternative disulphide binding pattern compared to the canonical TSP1 domains.
Pssm-ID: 465952 Cd Length: 44 Bit Score: 35.39 E-value: 6.98e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 1046900346 834 QVGNWSQCSTTCGLGAIwrlVRCSSGNDEdCTLSsrpQPARHCHLRPC 881
Cdd:pfam19035 4 QSTEWSPCSKTCGMGVS---TRVSNDNAE-CKLV---TETRLCQLRPC 44
|
|
| TSP1 |
smart00209 |
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta. |
944-988 |
7.31e-03 |
|
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
Pssm-ID: 214559 [Multi-domain] Cd Length: 53 Bit Score: 35.64 E-value: 7.31e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 1046900346 944 TSSWRECSEACGGGEQQRLVTC--PEPGLCEESLRPNN--TRPCNTHPC 988
Cdd:smart00209 4 WSEWSPCSVTCGGGVQTRTRSCcsPPPQNGGGPCTGEDveTRACNEQPC 52
|
|
| TSP1 |
smart00209 |
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta. |
887-939 |
7.39e-03 |
|
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
Pssm-ID: 214559 [Multi-domain] Cd Length: 53 Bit Score: 35.64 E-value: 7.39e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 1046900346 887 GNWSKCSRNCGGGSATRDVQCVDtrdlrPLRPFHCQPGPTKPPTRQLCGTQPC 939
Cdd:smart00209 5 SEWSPCSVTCGGGVQTRTRSCCS-----PPPQNGGGPCTGEDVETRACNEQPC 52
|
|
| |
