|
Name |
Accession |
Description |
Interval |
E-value |
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
30-216 |
9.63e-27 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 109.11 E-value: 9.63e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 30 DKGLQSISELSLDSTLHAVNLHCNNISKIEAIDHIWNLQHLDLSSNQISRIEGLNTLTKLCTLNLSCNLITKVEGLEELI 109
Cdd:cd21340 11 DKNITKIDNLSLCKNLKVLYLYDNKITKIENLEFLTNLTHLYLQNNQIEKIENLENLVNLKKLYLGGNRISVVEGLENLT 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 110 N------------------------------LTRLNVSYNHIDDLSGLIPLhgikHKLRYIDLHSNRIDSIHHLLQCMVG 159
Cdd:cd21340 91 NleelhienqrlppgekltfdprslaalsnsLRVLNISGNNIDSLEPLAPL----RNLEQLDASNNQISDLEELLDLLSS 166
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 1034661819 160 LHFLTNLILEkdgdDNPVCRLPgtslntvtlpselrGYRAVILQTLPQLRILDCKNI 216
Cdd:cd21340 167 WPSLRELDLT----GNPVCKKP--------------KYRDKIILASKSLEVLDGKEI 205
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
37-274 |
5.94e-13 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 71.89 E-value: 5.94e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 37 SELSLDSTLHAVNLHCNNISKI-EAIDHIWNLQHLDLSSNQISRI-EGLNTLTKLCTLNLSCNLITKVEGLEELINLTRL 114
Cdd:COG4886 176 EELGNLTNLKELDLSNNQITDLpEPLGNLTNLEELDLSGNQLTDLpEPLANLTNLETLDLSNNQLTDLPELGNLTNLEEL 255
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 115 NVSYNHIDDLSGLIPLHgikhKLRYIDLHSNRIDSIHHLLQCMVGLHFLTNLILEKDGDDNPVCRLPGTSLNTVTLPSEL 194
Cdd:COG4886 256 DLSNNQLTDLPPLANLT----NLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLK 331
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 195 RGYRAVILQTLPQLRILDCKNIFGEPVNLTEINSSQLQCLEGLLDNLVSSDSPLNISEDEIIDRMPVITAPIDELVPLEQ 274
Cdd:COG4886 332 GLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLALLLLTLLLLLLTTTAGVLLLTLALLDAV 411
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
31-343 |
6.24e-12 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 68.81 E-value: 6.24e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 31 KGLQSISELSLDSTLHAVNLHCNNISKIEAIDHIWNLQHLDLSSNQISRI-EGLNTLTKLCTLNLSCNLITKV-EGLEEL 108
Cdd:COG4886 79 LLLLSLLLLGLTDLGDLTNLTELDLSGNEELSNLTNLESLDLSGNQLTDLpEELANLTNLKELDLSNNQLTDLpEPLGNL 158
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 109 INLTRLNVSYNHIDDLSGliPLHGIKhKLRYIDLHSNRIDSIHHLLQcmvGLHFLTNLILekdgDDNPVCRLPG-----T 183
Cdd:COG4886 159 TNLKSLDLSNNQLTDLPE--ELGNLT-NLKELDLSNNQITDLPEPLG---NLTNLEELDL----SGNQLTDLPEplanlT 228
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 184 SLNTVTLP----SELRGyraviLQTLPQLRILDCKN-------IFGEPVNLTEINSS-------QLQCLEGLLDNLVSSD 245
Cdd:COG4886 229 NLETLDLSnnqlTDLPE-----LGNLTNLEELDLSNnqltdlpPLANLTNLKTLDLSnnqltdlKLKELELLLGLNSLLL 303
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 246 SPLNISEDEIIDRMPVITAPIDELVPLEQFASTPSDAVLTSFMSVCQSSEPEKNNHENDLQNEIKLQKLDDQILQLLNET 325
Cdd:COG4886 304 LLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLA 383
|
330
....*....|....*...
gi 1034661819 326 SNSIDNVLEKDPRPKRDT 343
Cdd:COG4886 384 LLLLTLLLLLLTTTAGVL 401
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
35-250 |
2.02e-10 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 64.18 E-value: 2.02e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 35 SISELSldsTLHAVNLHCNNISKI-EAIDHIWNLQHLDLSSNQISRIEGLNTLTKLCTLNLSCNLITKVEGLEELINLTR 113
Cdd:COG4886 200 PLGNLT---NLEELDLSGNQLTDLpEPLANLTNLETLDLSNNQLTDLPELGNLTNLEELDLSNNQLTDLPPLANLTNLKT 276
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 114 LNVSYNHIDDLS-GLIPLHGIKHKLRYIDLHSNRIDSIHHLLQCMVGLHFLTNLILEKDGDDNPVCRLPGTSLNTVTLPS 192
Cdd:COG4886 277 LDLSNNQLTDLKlKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLL 356
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 1034661819 193 ELRGYRAVILQTLPQLRILDCKNIFGEPVNLTEINSSQLQCLEGLLDNLVSSDSPLNI 250
Cdd:COG4886 357 NLLSLLLTLLLTLGLLGLLEATLLTLALLLLTLLLLLLTTTAGVLLLTLALLDAVNTE 414
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
417-1023 |
1.28e-09 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 62.38 E-value: 1.28e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 417 SEKPKTEIIKVDQSHSEDNTYQSLVEQLDQEREKRWRAEQAENKLMDYIDELHKHANEKEDIHslallttDRLKEIIFRE 496
Cdd:TIGR02168 298 SRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAEL-------EELEAELEEL 370
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 497 RNSKGQLEVMVHKLQNEIKKLTVELMKAKDQQEDHLKHLRTLEKTLEKMERQKRQQQAAQIRL-IQEVELKASAADREIY 575
Cdd:TIGR02168 371 ESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAeLKELQAELEELEEELE 450
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 576 LLRTSLHREREQAQQLHQLLALKEQEHRKELetREFFTDADFQDALAKEIAKEEKKHEQMIKEYQEK------IDVLSQQ 649
Cdd:TIGR02168 451 ELQEELERLEEALEELREELEEAEQALDAAE--RELAQLQARLDSLERLQENLEGFSEGVKALLKNQsglsgiLGVLSEL 528
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 650 yMDLENEFRIAL-TVEARRFQDV------------------RIGTQLFIE--------NRINLTCMVKEQKTKLAEVSKL 702
Cdd:TIGR02168 529 -ISVDEGYEAAIeAALGGRLQAVvvenlnaakkaiaflkqnELGRVTFLPldsikgteIQGNDREILKNIEGFLGVAKDL 607
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 703 kQETAANLQNQINTL--EILIEDDKQKSIQIELLKHEKVQLIS---EL-----------AAKESLIFGLRTERKVWGHEL 766
Cdd:TIGR02168 608 -VKFDPKLRKALSYLlgGVLVVDDLDNALELAKKLRPGYRIVTldgDLvrpggvitggsAKTNSSILERRREIEELEEKI 686
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 767 AQQGSSLA---QNRGKLEAQIESLSRENECLRKTNESDSDALRIKCKIIDDQTETIRKLKDCLQEKDEHIKRLQEKITEI 843
Cdd:TIGR02168 687 EELEEKIAeleKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEEL 766
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 844 EkctqEQLDEKSSQLDEVLEKLERHNERKEKLKQQLKGKEVELEEIRKAYSTLNRKWHDKGELLCHLETQVKEVKEKFEN 923
Cdd:TIGR02168 767 E----ERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLED 842
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 924 KEKKLKAERDKSIELQKNaMEKLHSMDDAFKRQVDAIVEAhQAEIAQLANEKQKCIDSANLKVHQIEKEMREL---LEET 1000
Cdd:TIGR02168 843 LEEQIEELSEDIESLAAE-IEELEELIEELESELEALLNE-RASLEEALALLRSELEELSEELRELESKRSELrreLEEL 920
|
650 660
....*....|....*....|...
gi 1034661819 1001 CKNKKTMEAKIKQLAFALNEIQQ 1023
Cdd:TIGR02168 921 REKLAQLELRLEGLEVRIDNLQE 943
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
492-867 |
1.91e-09 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 62.00 E-value: 1.91e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 492 IIFRERNSKgQLEVMVHKLQNEIKKLTVELMKAKDQQEDHLKHLRTLEKTLEKMERQKRQQQAAQIRLIQEVELKASAAD 571
Cdd:TIGR02168 672 ILERRREIE-ELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIA 750
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 572 ReiyllrtsLHREREQAQQLHQLLALKEQEHRKELetrefftdadfqdalaKEIAKEEKKHEQMIKEYQEKIDVLSQQYM 651
Cdd:TIGR02168 751 Q--------LSKELTELEAEIEELEERLEEAEEEL----------------AEAEAEIEELEAQIEQLKEELKALREALD 806
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 652 DLENEfriaLTVEARRFQDVRIGTQLfIENRINLTcmvKEQKTKLAEVSKLKQETAANLQNQINTLEILIEddkQKSIQI 731
Cdd:TIGR02168 807 ELRAE----LTLLNEEAANLRERLES-LERRIAAT---ERRLEDLEEQIEELSEDIESLAAEIEELEELIE---ELESEL 875
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 732 ELLKHEKVQLISELAAKESLIFGLRTERKVWG---HELAQQGSSLAQNRGKLEAQIESL-SRENECLRKTNESDSDALri 807
Cdd:TIGR02168 876 EALLNERASLEEALALLRSELEELSEELRELEskrSELRRELEELREKLAQLELRLEGLeVRIDNLQERLSEEYSLTL-- 953
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1034661819 808 kckiiDDQTETIRKLKDCLQEKDEHIKRLQEKITEI-------------EKCTQEQLDEKSSQLDEVLEKLER 867
Cdd:TIGR02168 954 -----EEAEALENKIEDDEEEARRRLKRLENKIKELgpvnlaaieeyeeLKERYDFLTAQKEDLTEAKETLEE 1021
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
535-892 |
3.90e-09 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 60.72 E-value: 3.90e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 535 LRTLEKTLEKmerqkrqqqaaqirliqeveLKASAADREIYLlrtSLHREREQAQQLHQLLALKEQEHRKELETREfftd 614
Cdd:COG1196 195 LGELERQLEP--------------------LERQAEKAERYR---ELKEELKELEAELLLLKLRELEAELEELEAE---- 247
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 615 ADFQDALAKEIAKEEKKHEQMIKEYQEKIDVLSQQYMDLENEFRIALTVEARRFQDVRIGTQLFIENRINLtcmvKEQKT 694
Cdd:COG1196 248 LEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERL----EELEE 323
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 695 KLAEVSKLKQETAANLQNQINTLEILIEDDKQKSIQIELLKHEKVQLISELAAKESLIFGLRTERKvwghELAQQGSSLA 774
Cdd:COG1196 324 ELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELL----EALRAAAELA 399
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 775 QNRGKLEAQIESLSRENECLRKTNESDSDALRIKCKIIDDQTETIRKLKDCLQEKDEHIKRLQEKITEiekcTQEQLDEK 854
Cdd:COG1196 400 AQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAE----LLEEAALL 475
|
330 340 350
....*....|....*....|....*....|....*...
gi 1034661819 855 SSQLDEVLEKLERHNERKEKLKQQLKGKEVELEEIRKA 892
Cdd:COG1196 476 EAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAA 513
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
580-899 |
6.25e-09 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 60.46 E-value: 6.25e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 580 SLHREREQAQQLHqllALKEQEhrKELETREFFTDADFQDALAKEIAKEEKKHEQMIKEYQEKIDVLSQQYMDLENEFRi 659
Cdd:TIGR02168 204 SLERQAEKAERYK---ELKAEL--RELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVS- 277
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 660 altvEARRFQDVRIGTQLFIENRIN-LTCMVKEQKTKLAEVSKLKQETAANLQNQINTLEILIEDDKQKSIQIELLKHEK 738
Cdd:TIGR02168 278 ----ELEEEIEELQKELYALANEISrLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEEL 353
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 739 VQLISELAAKESLIFGLRTERkvwgHELAQQGSSLAQNRGKLEAQIESLsreneclrktnesdsdalrikckiiddqTET 818
Cdd:TIGR02168 354 ESLEAELEELEAELEELESRL----EELEEQLETLRSKVAQLELQIASL----------------------------NNE 401
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 819 IRKLKDCLQEKDEHIKRLQEKITEIEKCTQEQldekssQLDEVLEKLERHNERKEKLKQQLKGKEVELEEIRKAYSTLNR 898
Cdd:TIGR02168 402 IERLEARLERLEDRRERLQQEIEELLKKLEEA------ELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQ 475
|
.
gi 1034661819 899 K 899
Cdd:TIGR02168 476 A 476
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
295-888 |
9.17e-08 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 56.28 E-value: 9.17e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 295 EPEKNNHENDLqnEIKLQKLDDQILQLLNETSNSIDNVLEKDPRPKRDTD-ITSESDYGNRKECNRKVPRRSKIPYDAKT 373
Cdd:pfam15921 248 EALKSESQNKI--ELLLQQHQDRIEQLISEHEVEITGLTEKASSARSQANsIQSQLEIIQEQARNQNSMYMRQLSDLEST 325
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 374 IQTIKhhnknynSFVSCNRKMKPPYLKELYVSSSLANcpmlQESEKPKTEIIKVDQ-SHSEDNTYQSLVEQLdQEREKRW 452
Cdd:pfam15921 326 VSQLR-------SELREAKRMYEDKIEELEKQLVLAN----SELTEARTERDQFSQeSGNLDDQLQKLLADL-HKREKEL 393
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 453 RAEQAENK-LMD-------YIDELHKHANEKEdihslalLTTDRLKEIIFRERNS-KGQLEVMVHKLQ------NEIKKL 517
Cdd:pfam15921 394 SLEKEQNKrLWDrdtgnsiTIDHLRRELDDRN-------MEVQRLEALLKAMKSEcQGQMERQMAAIQgkneslEKVSSL 466
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 518 TVELMKAKDQQEDHLKHLRTLEKTLEKMERQKRQQQAAqirlIQEVELKASAADREIYLLRTSLHREREQAQQLHQllal 597
Cdd:pfam15921 467 TAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTAS----LQEKERAIEATNAEITKLRSRVDLKLQELQHLKN---- 538
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 598 kEQEHRKELETRefftdadfQDALAKEIAKEEKkheqmikeyqeKIDVLSQQymdLENEFRIAltvearrFQDVRIGTQL 677
Cdd:pfam15921 539 -EGDHLRNVQTE--------CEALKLQMAEKDK-----------VIEILRQQ---IENMTQLV-------GQHGRTAGAM 588
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 678 FIEnRINLTCMVKEQKTKLAEVSKLKQETAAN---LQNQINTLEI----LIEDDKQKSIQIELLKHEKVQLISELAAKES 750
Cdd:pfam15921 589 QVE-KAQLEKEINDRRLELQEFKILKDKKDAKireLEARVSDLELekvkLVNAGSERLRAVKDIKQERDQLLNEVKTSRN 667
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 751 LIFGLRTERKVWGHELAQQGSSLAQNRGKLEAQIESLSRENECLRKTNES--DSDALRIKCKI-IDDQTETIRKLKDCLQ 827
Cdd:pfam15921 668 ELNSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSmeGSDGHAMKVAMgMQKQITAKRGQIDALQ 747
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1034661819 828 EKdehIKRLQEKITEIEKcTQEQLDEKSSQLDEVLE-----------KLERHNERKEKLKQQLKGKEVELEE 888
Cdd:pfam15921 748 SK---IQFLEEAMTNANK-EKHFLKEEKNKLSQELStvateknkmagELEVLRSQERRLKEKVANMEVALDK 815
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
560-914 |
1.51e-07 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 55.84 E-value: 1.51e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 560 IQEVELKASAADREIYLLRTSLHR---EREQAQQLHQLLALKE-----------QEHRKELETreffTDADFqDALAKEI 625
Cdd:TIGR02169 179 LEEVEENIERLDLIIDEKRQQLERlrrEREKAERYQALLKEKReyegyellkekEALERQKEA----IERQL-ASLEEEL 253
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 626 AKEEKKHEQMIKEYQEKIDVLSQqymdlenefrialtvEARRFQDVRIGTQLFIenrinltcmvkeqKTKLAEVsklkqe 705
Cdd:TIGR02169 254 EKLTEEISELEKRLEEIEQLLEE---------------LNKKIKDLGEEEQLRV-------------KEKIGEL------ 299
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 706 taanlQNQINTLEILIEDDKQksiQIELLKHEKVQLISELAAKESLIFGLRTERKVWGHELAQQGS---SLAQNRGKLEA 782
Cdd:TIGR02169 300 -----EAEIASLERSIAEKER---ELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEeyaELKEELEDLRA 371
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 783 QIESLSRENECLRKTNESDSDALRIKCKIIDDQTETIRKLKDCLQEKDEHIKRLQEKITEIEkctqEQLDEKSSQLDEVL 862
Cdd:TIGR02169 372 ELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIE----AKINELEEEKEDKA 447
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|..
gi 1034661819 863 EKLERHNERKEKLKQQLKGKEVELEEIRKAYSTLNRKWHDKGELLCHLETQV 914
Cdd:TIGR02169 448 LEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQA 499
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
564-879 |
2.14e-07 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 55.06 E-value: 2.14e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 564 ELKASAADREIYLLRTSLHREREQAQQLHQLLALKEQEHrKELETREFFTDADFqDALAKEIAKEEKKheqmIKEYQEKI 643
Cdd:TIGR02168 217 ELKAELRELELALLVLRLEELREELEELQEELKEAEEEL-EELTAELQELEEKL-EELRLEVSELEEE----IEELQKEL 290
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 644 DVLSQQYMDLENEFRIAltveARRFQDVRIGTQLFIENRINLTCMVKEQKTKLAEVSKLKQEtaanLQNQINTLEILIED 723
Cdd:TIGR02168 291 YALANEISRLEQQKQIL----RERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEE----LKEELESLEAELEE 362
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 724 DKQKSIQIELLKHEKVQLISELAAKEslifglrterkvwgHELAQQGSSLAQNRGKLEAQIESLSRENECLRKTNESDSD 803
Cdd:TIGR02168 363 LEAELEELESRLEELEEQLETLRSKV--------------AQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLK 428
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1034661819 804 AL-RIKCKIIDDQTETIRKLKDCLQEKDEHIKRLQEKIteiekctQEQLDEKSSQLDEVLEKLERHNERKEKLKQQL 879
Cdd:TIGR02168 429 KLeEAELKELQAELEELEEELEELQEELERLEEALEEL-------REELEEAEQALDAAERELAQLQARLDSLERLQ 498
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
697-1023 |
2.67e-07 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 55.06 E-value: 2.67e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 697 AEVSKLKQ----------ETAANLQnQINtlEILIEDDKQ-KSIQIELLKHEKVQ-LISELAAKESLIFGLRTERKVWG- 763
Cdd:TIGR02168 165 AGISKYKErrketerkleRTRENLD-RLE--DILNELERQlKSLERQAEKAERYKeLKAELRELELALLVLRLEELREEl 241
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 764 HELAQQGSSLAQNRGKLEAQIESLSRENECLRKTNESDSDALRIKCKIIDDQTETIRKLKDCLQEKDEHIKRLQEKITEI 843
Cdd:TIGR02168 242 EELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEEL 321
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 844 EkctqEQLDEKSSQLDEVLEKLERHNERKEKLKQQLKGKEVELEEIRKAYSTLNRKWHDKGELLCHLETQVKEVKEKFEN 923
Cdd:TIGR02168 322 E----AQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIAS 397
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 924 KEKKLKAERDKSIELQKNAMEKLHSMDDAFKRQVDAIVEAHQAEIA---QLANEKQKCIDSANLKVHQIEKEMRELLEET 1000
Cdd:TIGR02168 398 LNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEeleEELEELQEELERLEEALEELREELEEAEQAL 477
|
330 340
....*....|....*....|...
gi 1034661819 1001 CKNKKTmEAKIKQLAFALNEIQQ 1023
Cdd:TIGR02168 478 DAAERE-LAQLQARLDSLERLQE 499
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
455-1014 |
2.79e-07 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 54.74 E-value: 2.79e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 455 EQAENKLMDY---IDELHKHANEKEDIHS----------------LALLTTDRLKEIIFRERNSKGQlevmvHKLQNEIK 515
Cdd:pfam15921 74 EHIERVLEEYshqVKDLQRRLNESNELHEkqkfylrqsvidlqtkLQEMQMERDAMADIRRRESQSQ-----EDLRNQLQ 148
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 516 KLTVELMKAKDQQEDHLKHLRTLEKTLEKMERQKRQQQAAQIRLIQEVElkaSAADREIYllrtslhrEREQAQQLH-QL 594
Cdd:pfam15921 149 NTVHELEAAKCLKEDMLEDSNTQIEQLRKMMLSHEGVLQEIRSILVDFE---EASGKKIY--------EHDSMSTMHfRS 217
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 595 LALKEQEHRKELETREFFtdadfqdaLAKEIAKEEKKHEQMIKEYQEKIDVLSQQYMD----LENEFRIALT-----VEA 665
Cdd:pfam15921 218 LGSAISKILRELDTEISY--------LKGRIFPVEDQLEALKSESQNKIELLLQQHQDrieqLISEHEVEITgltekASS 289
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 666 RRFQDVRIGTQLFI--ENRINLTCMVKEQKTKLaevsklkQETAANLQNQINTLEILIEDdkqksiQIELLKHEKVQLIS 743
Cdd:pfam15921 290 ARSQANSIQSQLEIiqEQARNQNSMYMRQLSDL-------ESTVSQLRSELREAKRMYED------KIEELEKQLVLANS 356
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 744 ELAAKeslifglRTERKVWGHELAQQGSSLAQNRGKLEAQIESLSRENECLRKTNESDS------DALRikcKIIDDQTE 817
Cdd:pfam15921 357 ELTEA-------RTERDQFSQESGNLDDQLQKLLADLHKREKELSLEKEQNKRLWDRDTgnsitiDHLR---RELDDRNM 426
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 818 TIRKLK--------DCLQEKDEHIKRLQEKITEIEKCTQ--EQLDEKSSQLDEVLEK-------LERHNERKEKLKQQLK 880
Cdd:pfam15921 427 EVQRLEallkamksECQGQMERQMAAIQGKNESLEKVSSltAQLESTKEMLRKVVEEltakkmtLESSERTVSDLTASLQ 506
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 881 GKEVELEEIRKAYSTLNRKWHDKGELLCHLETQVKEVKEKFEN--KEKKLKAERDKSIELQKNAMEKLHSMDDAFKRQVD 958
Cdd:pfam15921 507 EKERAIEATNAEITKLRSRVDLKLQELQHLKNEGDHLRNVQTEceALKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAG 586
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....*.
gi 1034661819 959 AIveahQAEIAQLANEkqkcIDSANLKVhqieKEMRELLEETCKNKKTMEAKIKQL 1014
Cdd:pfam15921 587 AM----QVEKAQLEKE----INDRRLEL----QEFKILKDKKDAKIRELEARVSDL 630
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
511-853 |
7.78e-07 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 53.52 E-value: 7.78e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 511 QNEIKKLTVELMKAKDQQEDHLKHLRTLEKTLEKMERQKRQQQAAQIRLiqevelkasaaDREIYLLRTSLHREREQAQQ 590
Cdd:TIGR02168 676 RREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEEL-----------SRQISALRKDLARLEAEVEQ 744
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 591 LHQLLALKEQEhRKELETREFFTDADFQDALAKEIAKEEK--KHEQMIKEYQEKIDVLSQQYMDLENEfriaLTVEARRF 668
Cdd:TIGR02168 745 LEERIAQLSKE-LTELEAEIEELEERLEEAEEELAEAEAEieELEAQIEQLKEELKALREALDELRAE----LTLLNEEA 819
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 669 QDVRIGTQLfIENRINLTcmvKEQKTKLAEVSKLKQETAANLQNQINTLEILIE----------DDKQKSIQ-IELLKHE 737
Cdd:TIGR02168 820 ANLRERLES-LERRIAAT---ERRLEDLEEQIEELSEDIESLAAEIEELEELIEeleseleallNERASLEEaLALLRSE 895
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 738 KVQLISELAAKESLIFGLRTERKVWGHELAQQGSSLAQNRGKLEAQIESLSRE-----NECLRKTNESDSDALRIKCKII 812
Cdd:TIGR02168 896 LEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEysltlEEAEALENKIEDDEEEARRRLK 975
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1034661819 813 DDQT-------------ETIRKLKDCLQEKDEHI-------KRLQEKITEIEKCTQEQLDE 853
Cdd:TIGR02168 976 RLENkikelgpvnlaaiEEYEELKERYDFLTAQKedlteakETLEEAIEEIDREARERFKD 1036
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
445-1020 |
9.04e-07 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 53.15 E-value: 9.04e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 445 DQEREKRWRAEQAENKLMDYIDELHKHANEKEDihslallttdrLKEIIFRERNSKGQLEVMVHKLQNEIKKLTVELmka 524
Cdd:TIGR02169 308 RSIAEKERELEDAEERLAKLEAEIDKLLAEIEE-----------LEREIEEERKRRDKLTEEYAELKEELEDLRAEL--- 373
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 525 kdqQEDHLKHLRTLEKTlekmerqkrqqqaaqirliQEVELKASAADREIYLLRTSLHREREQAQQLHQLLA-LKEQEHR 603
Cdd:TIGR02169 374 ---EEVDKEFAETRDEL-------------------KDYREKLEKLKREINELKRELDRLQEELQRLSEELAdLNAAIAG 431
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 604 KELETREFFTDADfqdALAKEIAKEEKKHEQ---MIKEYQEKIDVLSQQYMDLENEFRIA----LTVEARRfQDVRIGTQ 676
Cdd:TIGR02169 432 IEAKINELEEEKE---DKALEIKKQEWKLEQlaaDLSKYEQELYDLKEEYDRVEKELSKLqrelAEAEAQA-RASEERVR 507
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 677 LFIENRINLTCMVKEQKTKLAEVSKLKQETAANLQ----NQINTleILIEDDKQKSIQIELLKHEK-------------- 738
Cdd:TIGR02169 508 GGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEvaagNRLNN--VVVEDDAVAKEAIELLKRRKagratflplnkmrd 585
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 739 ----VQLISELAAKESLIFGLRTERK-------VWGHELAQQGSSLAQnrgKLEAQIESLSRENECL------------R 795
Cdd:TIGR02169 586 errdLSILSEDGVIGFAVDLVEFDPKyepafkyVFGDTLVVEDIEAAR---RLMGKYRMVTLEGELFeksgamtggsraP 662
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 796 KTNESDSDALRIKCKIIDDQTETIRKLKDCLQEKDEHIK-RLQEKITEIEKCTQEqLDEKSSQLDEVLEKLERHNERKEK 874
Cdd:TIGR02169 663 RGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIEnRLDELSQELSDASRK-IGEIEKEIEQLEQEEEKLKERLEE 741
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 875 LKQQLKGKEVELEEIRKAYSTLNRKWHDKGELLCHLETQVKEVKEKFENkekklkaERDKSIELQKNAMEKLHSMDDAFK 954
Cdd:TIGR02169 742 LEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSH-------SRIPEIQAELSKLEEEVSRIEARL 814
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1034661819 955 RQVDAIVEAHQAEIAQLANEKQKCIDSANLKVHQIeKEMRELLEETCKNKKTMEAKIKQLAFALNE 1020
Cdd:TIGR02169 815 REIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQI-KSIEKEIENLNGKKEELEEELEELEAALRD 879
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
442-890 |
1.94e-06 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 51.96 E-value: 1.94e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 442 EQLDQEREKRWRAEQAE-----NKLMDYIDELHKHANEKEDIHSLALLTTDRLKEIIFRERNSKGQLEVmvhkLQNEIKK 516
Cdd:PRK02224 187 GSLDQLKAQIEEKEEKDlherlNGLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERREELET----LEAEIED 262
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 517 LTVELMKAKDQQEDHLKHLRTLEKTLEKMERQKRQqqaaqirLIQEVELKaSAADREIYLLRTSLHREREQAQQLHQLLA 596
Cdd:PRK02224 263 LRETIAETEREREELAEEVRDLRERLEELEEERDD-------LLAEAGLD-DADAEAVEARREELEDRDEELRDRLEECR 334
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 597 LKEQEHRKELET-REFFTDADFQDA----LAKEIAKEEKKHEQMIKEYQEKIDVLSQQYMDLENEFRIAlTVEARRFQDV 671
Cdd:PRK02224 335 VAAQAHNEEAESlREDADDLEERAEelreEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDA-PVDLGNAEDF 413
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 672 RigtQLFIENRINLTCMVKEQKTKLAEVSKLKQE------------------------TAANLQNQINTLEILIEDDKQK 727
Cdd:PRK02224 414 L---EELREERDELREREAELEATLRTARERVEEaealleagkcpecgqpvegsphveTIEEDRERVEELEAELEDLEEE 490
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 728 SIQIEllkhEKVQLISELAAKESLIFGLRTERKVWGHELAQQGSSLAQNRGKLE------AQIESLSRENECLRKTNESD 801
Cdd:PRK02224 491 VEEVE----ERLERAEDLVEAEDRIERLEERREDLEELIAERRETIEEKRERAEelreraAELEAEAEEKREAAAEAEEE 566
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 802 SDALRIKCKIID----------DQTETIRKLKDCLQEKDEHIKRLQEK---ITEIEKCTQEQLDEKSSQ----------- 857
Cdd:PRK02224 567 AEEAREEVAELNsklaelkeriESLERIRTLLAAIADAEDEIERLREKreaLAELNDERRERLAEKRERkreleaefdea 646
|
490 500 510 520
....*....|....*....|....*....|....*....|....*...
gi 1034661819 858 ---------------LDEVLEKLERHNERKEKLKQQLKGKEVELEEIR 890
Cdd:PRK02224 647 rieearedkeraeeyLEQVEEKLDELREERDDLQAEIGAVENELEELE 694
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
508-905 |
2.00e-06 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 51.69 E-value: 2.00e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 508 HKLQNEIKKLTVELMKAKDQQEDHLKHLRTLEKTLEKMERQKRQQQAAqiRLIQEVELKASAADREIYLLRTSLHREREQ 587
Cdd:COG4717 91 AELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALE--AELAELPERLEELEERLEELRELEEELEEL 168
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 588 AQQLHQLlalkEQEHRKELETREFFTDADFQDALAK--EIAKEEKKHEQMIKEYQEKIDVLSQQYMDLENEFRIALTVEA 665
Cdd:COG4717 169 EAELAEL----QEELEELLEQLSLATEEELQDLAEEleELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEER 244
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 666 RRFQDVRIGTQLFIENRINLTCMVKEQKTKLAEVSKLKQETAANLQNQINTLEILIEDDKQKSIQIELLKHEKVQLISEL 745
Cdd:COG4717 245 LKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEEL 324
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 746 AAKESLIFGLRTERKVWGHELAQQGSSLAQNRGKLEAQIESLSRENEC---LRKTNESDSDALRIKCKIIDDQTETIRKL 822
Cdd:COG4717 325 LAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIaalLAEAGVEDEEELRAALEQAEEYQELKEEL 404
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 823 KDCLQEKDEHIKRLQEKITEIEKCT-QEQLDEKSSQLDEVLEKLERHNERKEKLKQQLK--GKEVELEEIRKAYSTLNRK 899
Cdd:COG4717 405 EELEEQLEELLGELEELLEALDEEElEEELEELEEELEELEEELEELREELAELEAELEqlEEDGELAELLQELEELKAE 484
|
....*.
gi 1034661819 900 WHDKGE 905
Cdd:COG4717 485 LRELAE 490
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
680-1013 |
2.04e-06 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 51.94 E-value: 2.04e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 680 ENRINLTCMVKEQKTKLAEVSKLKQETAANLQNQINTLEILIEDDKQKSIQIELLKHEKVQLISELAAKESLIFGLRTER 759
Cdd:TIGR04523 117 EQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKL 196
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 760 KVWGHELAQQGSSLAQNRgKLEAQIESLSRENECLRKTNESDSDALRIKCKIIDdqtETIRKLKDCLQEKDEHIKRLQEK 839
Cdd:TIGR04523 197 LKLELLLSNLKKKIQKNK-SLESQISELKKQNNQLKDNIEKKQQEINEKTTEIS---NTQTQLNQLKDEQNKIKKQLSEK 272
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 840 ITEIEKcTQEQLDEKSSQLDEVLEKLERHNERKE-----KLKQQLKGKEVELEEIRKAYSTLNRKWHDKGELLCHLETQV 914
Cdd:TIGR04523 273 QKELEQ-NNKKIKELEKQLNQLKSEISDLNNQKEqdwnkELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKEL 351
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 915 KEVKEKFEnkekklkaERDKSIELQKNAMEKLHSMDDAFKRQVD------AIVEAHQAEIAQLANEKQKCIDSANLKVHQ 988
Cdd:TIGR04523 352 TNSESENS--------EKQRELEEKQNEIEKLKKENQSYKQEIKnlesqiNDLESKIQNQEKLNQQKDEQIKKLQQEKEL 423
|
330 340
....*....|....*....|....*
gi 1034661819 989 IEKEMRELLEETCKNKKTMEAKIKQ 1013
Cdd:TIGR04523 424 LEKEIERLKETIIKNNSEIKDLTNQ 448
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
690-892 |
2.88e-06 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 50.60 E-value: 2.88e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 690 KEQKTKLAEVSKLKQETAANLQNQINTLEILIEDDKQKSIQIELLKHEKVQLISELAAKESLIFGLRTERKVWGHELAQQ 769
Cdd:COG3883 19 QAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALYRS 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 770 GSSLaqnrGKLEAQIESlsreneclrktnESDSDAL-RIK--CKIIDDQTETIRKLKDCLQEKDEHIKRLQEKITEIEKC 846
Cdd:COG3883 99 GGSV----SYLDVLLGS------------ESFSDFLdRLSalSKIADADADLLEELKADKAELEAKKAELEAKLAELEAL 162
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 1034661819 847 TQEQLDEKS---SQLDEVLEKLERHNERKEKLKQQLKGKEVELEEIRKA 892
Cdd:COG3883 163 KAELEAAKAeleAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAA 211
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
517-802 |
3.69e-06 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 50.53 E-value: 3.69e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 517 LTVELMKAKDQQEDHLKHLRTLEKTLEKMErqkrqqqaaqiRLIQEVELKASAADREIYLLRTSLHREREQAQQLHQLLA 596
Cdd:COG4942 11 LALAAAAQADAAAEAEAELEQLQQEIAELE-----------KELAALKKEEKALLKQLAALERRIAALARRIRALEQELA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 597 LKEQEHRKeletrefftdadfqdaLAKEIAKEEKKHEQMIKEYQEKIDVLSQqymdLENEFRIALTVEARRFQDVRIGTQ 676
Cdd:COG4942 80 ALEAELAE----------------LEKEIAELRAELEAQKEELAELLRALYR----LGRQPPLALLLSPEDFLDAVRRLQ 139
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 677 LFIENRINLTCMVKEQKTKLAEVSKLKQEtaanLQNQINTLEILIEDDKQKSIQIELLKHEKVQLISELAAKESlifglr 756
Cdd:COG4942 140 YLKYLAPARREQAEELRADLAELAALRAE----LEAERAELEALLAELEEERAALEALKAERQKLLARLEKELA------ 209
|
250 260 270 280
....*....|....*....|....*....|....*....|....*.
gi 1034661819 757 terkvwghELAQQGSSLAQNRGKLEAQIESLSRENECLRKTNESDS 802
Cdd:COG4942 210 --------ELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAG 247
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
437-1023 |
5.51e-06 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 50.83 E-value: 5.51e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 437 YQSLVEQLDQEREKRWRAEQAENKLMDYIDELHKHANEKEDIHS-----LALLTTD--RLKEIIFRERNSKGQLEVMVHK 509
Cdd:TIGR02168 234 LEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSeleeeIEELQKElyALANEISRLEQQKQILRERLAN 313
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 510 LQNEIKKLTVELMKAKDQQEDHLKHLRTLEKTLEKMERQKRQQQAAQIRL---IQEVELKASAADREIYLLRTSLHRERE 586
Cdd:TIGR02168 314 LERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELeaeLEELESRLEELEEQLETLRSKVAQLEL 393
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 587 QAQ----QLHQLLALKEQ--EHRKELETREFFTDADFQDALAKEIAKEEKKHEQMIKEYQEKIDVLSQQYMDLENEFRIA 660
Cdd:TIGR02168 394 QIAslnnEIERLEARLERleDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEA 473
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 661 LT-VEARRFQDVRIGTQLFIENRInltcmvkeqktkLAEVSKLKQETAANLQNQ------INTLEILIEDDKQKSIQIEL 733
Cdd:TIGR02168 474 EQaLDAAERELAQLQARLDSLERL------------QENLEGFSEGVKALLKNQsglsgiLGVLSELISVDEGYEAAIEA 541
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 734 LKHEKVQ--LISELAAKESLIFGLRTERKVWGHELAQQGSSLAQNRGKLEaqiESLSRENECLRKTNESDSDALRIK--- 808
Cdd:TIGR02168 542 ALGGRLQavVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDR---EILKNIEGFLGVAKDLVKFDPKLRkal 618
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 809 ------CKIIDDQTETIRKLKDCLQE-----KDEHIKRLQEKITEIEKCTQEQLDEKSSQLDEVLEKLERHNERKEKLKQ 877
Cdd:TIGR02168 619 syllggVLVVDDLDNALELAKKLRPGyrivtLDGDLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEK 698
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 878 QLKGKEVELEEIRKAYSTLNRKWHDKGELLCHLETQVKEVKEKFENKEKKLKAERDKSIELQKNAM---EKLHSMDDAFK 954
Cdd:TIGR02168 699 ALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEeleERLEEAEEELA 778
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1034661819 955 RQVDAIVEAhQAEIAQLANEKQ---KCIDSANLKVHQIEKEMRELLEETCKNKKTMEAKIKQLAFALNEIQQ 1023
Cdd:TIGR02168 779 EAEAEIEEL-EAQIEQLKEELKalrEALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEE 849
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
830-1024 |
6.11e-06 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 49.83 E-value: 6.11e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 830 DEHIKRLQEKITEIekctQEQLDEKSSQLDEVLEKLERHNERKEKLKQQLKGKEVELEEIRKAYSTLNRKWHDKGELLch 909
Cdd:COG3883 15 DPQIQAKQKELSEL----QAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREEL-- 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 910 letqvkevkekfenkekklkAERDKSIELQKNAMEKL------HSMDDAFKRQ--VDAIVEAHQAEIAQLANEKQKcIDS 981
Cdd:COG3883 89 --------------------GERARALYRSGGSVSYLdvllgsESFSDFLDRLsaLSKIADADADLLEELKADKAE-LEA 147
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 1034661819 982 ANLKVHQIEKEMRELLEETCKNKKTMEAKIKQLAFALNEIQQD 1024
Cdd:COG3883 148 KKAELEAKLAELEALKAELEAAKAELEAQQAEQEALLAQLSAE 190
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
441-1025 |
9.40e-06 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 49.94 E-value: 9.40e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 441 VEQLDQEREK--RWRAEQAENKLMD---YIDELHKHANEKEDIHSLALLTTDRLKEIIFRERNSKGQLEvmvhKLQNEIK 515
Cdd:COG1196 202 LEPLERQAEKaeRYRELKEELKELEaelLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELE----ELRLELE 277
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 516 KLTVELmkaKDQQEDHLKHLRTLEKTLEKMERQKRQQQAAQIRLIQEVELKASAADREIYLLRTSLHREREQAQQLHQLL 595
Cdd:COG1196 278 ELELEL---EEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELE 354
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 596 ALKEQEHRKELETREFFTDADFQDALAKEIAKEEKKHEQMIKEYQEKIDVLSQQYMDLENEFRIALTVEARRFQDVRIGT 675
Cdd:COG1196 355 EAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELE 434
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 676 QLFIENRINLTCMVKEQKTKLAEVSKLKQETAAnLQNQINTLEILIEDDKQKSIQIELLKHEKVQLISELAAKESliFGL 755
Cdd:COG1196 435 EEEEEEEEALEEAAEEEAELEEEEEALLELLAE-LLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLE--GVK 511
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 756 RTERKVWGHELAQQGSSLAQNRGKLEAQIESlSRENECLRKTNESDSDALRikckIIDDQTET---------IRKLKDCL 826
Cdd:COG1196 512 AALLLAGLRGLAGAVAVLIGVEAAYEAALEA-ALAAALQNIVVEDDEVAAA----AIEYLKAAkagratflpLDKIRARA 586
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 827 QEKDEHIKRLQEKITEIEKCTQEQLDEKSSQLDEVLEKLERHNERKEKLKQQLKGKEVELEEIRKAYSTLNRKwhdkgel 906
Cdd:COG1196 587 ALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAG------- 659
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 907 lcHLETQVKEVKEKFENKEKKLKAERDKSIELQKNAMEKLHSMDDAFKRQVDAIVEAHQAEIAQLANEKQKCIDSANLKV 986
Cdd:COG1196 660 --GSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREEL 737
|
570 580 590
....*....|....*....|....*....|....*....
gi 1034661819 987 HQIEKEMRELLEETCKNKKTMEAKIKQLAFALNEIQQDM 1025
Cdd:COG1196 738 LEELLEEEELLEEEALEELPEPPDLEELERELERLEREI 776
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
559-890 |
9.45e-06 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 49.51 E-value: 9.45e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 559 LIQEVElkasAADREIYLLRTSLHREREQAQQLHQLLALKEQEHRKEL-ETREFFTD--------ADFQDALAKE---IA 626
Cdd:pfam07888 46 LLQAQE----AANRQREKEKERYKRDREQWERQRRELESRVAELKEELrQSREKHEEleekykelSASSEELSEEkdaLL 121
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 627 KEEKKHEQMIKEYQEKIDVLSQQYMDLENEF-RIALTVEA-----RRFQDVRIGTQLFIENRINLTCMVKEQKTKLAEVS 700
Cdd:pfam07888 122 AQRAAHEARIRELEEDIKTLTQRVLERETELeRMKERAKKagaqrKEEEAERKQLQAKLQQTEEELRSLSKEFQELRNSL 201
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 701 KLKQETAANLQNQINTLEILIEDDKQKSIQIELLKHEKVQLISELAAKESLIFGLRTERKVWGH--------------EL 766
Cdd:pfam07888 202 AQRDTQVLQLQDTITTLTQKLTTAHRKEAENEALLEELRSLQERLNASERKVEGLGEELSSMAAqrdrtqaelhqarlQA 281
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 767 AQQGSSLAQNRGKLEAQIESLSRENECLRKTNESDSDalrikckiiddqteTIRKLKDCLQEKDEhikRLQEKITEIEKC 846
Cdd:pfam07888 282 AQLTLQLADASLALREGRARWAQERETLQQSAEADKD--------------RIEKLSAELQRLEE---RLQEERMEREKL 344
|
330 340 350 360
....*....|....*....|....*....|....*....|....
gi 1034661819 847 TQEQLDEKSSQLDEVLEKLERHNERKEKLKQQLKGKEVELEEIR 890
Cdd:pfam07888 345 EVELGREKDCNRVQLSESRRELQELKASLRVAQKEKEQLQAEKQ 388
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
442-1023 |
9.50e-06 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 50.14 E-value: 9.50e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 442 EQLDQEREKRWRAEQAENKLMDYIDELHKHANEKEDIHSLalltTDRLKEIIFRERNSKGQLEVMvhKLQNEIKKLTVEL 521
Cdd:PTZ00121 1281 DELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEA----KKKAEEAKKKADAAKKKAEEA--KKAAEAAKAEAEA 1354
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 522 MKAKDQQEDHLKHLRTLEKTLEKMERQKRQQQAAQIRLIQEVELKASAADREIYLLRTSlHREREQAQQLHQllalKEQE 601
Cdd:PTZ00121 1355 AADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKA-AAAKKKADEAKK----KAEE 1429
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 602 HRKELETREFFTDADFQDALAKEiAKEEKKHEQMIKEYQE--KIDVLSQQymdlenefrialTVEARRFQDVRIGTQlfi 679
Cdd:PTZ00121 1430 KKKADEAKKKAEEAKKADEAKKK-AEEAKKAEEAKKKAEEakKADEAKKK------------AEEAKKADEAKKKAE--- 1493
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 680 enrinlTCMVKEQKTKLAEVSKLKQETAANLQNQINTLEILIEDDKQKSIqiELLKHEKVQLISELAAKESLifglrteR 759
Cdd:PTZ00121 1494 ------EAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKAD--EAKKAEEKKKADELKKAEEL-------K 1558
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 760 KvwghelaqqgsslAQNRGKLEAQIESLSRENECLRKTNES-DSDALRIKCKIIDDQTETIRKLKDCLQEKDEHIKRLQE 838
Cdd:PTZ00121 1559 K-------------AEEKKKAEEAKKAEEDKNMALRKAEEAkKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEEL 1625
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 839 KITEIEKCTQEQLDEKSSQLDEVLEKLERHNERKEKLKQQLKGKEVE----LEEIRKAYSTLNRKwhdKGELLCHLETQV 914
Cdd:PTZ00121 1626 KKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEdkkkAEEAKKAEEDEKKA---AEALKKEAEEAK 1702
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 915 KEVKEKFENKEKKLKAER-DKSIELQKNAMEKLHSMDDAFKRQVDA--IVEAHQAEIAQLANEKQKCIDSANLKVHQIEK 991
Cdd:PTZ00121 1703 KAEELKKKEAEEKKKAEElKKAEEENKIKAEEAKKEAEEDKKKAEEakKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIE 1782
|
570 580 590
....*....|....*....|....*....|..
gi 1034661819 992 EmrELLEETCKNKKTMEAKIKQLAFALNEIQQ 1023
Cdd:PTZ00121 1783 E--ELDEEDEKRRMEVDKKIKDIFDNFANIIE 1812
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
414-1017 |
9.91e-06 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 49.68 E-value: 9.91e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 414 LQESEKPKTEIIKvdqshsEDNTYQSLVEQLDQEREKRWRAEQAENKLMDYIDELHKhanEKEDIHSLALLTTDRLKEII 493
Cdd:PRK03918 195 IKEKEKELEEVLR------EINEISSELPELREELEKLEKEVKELEELKEEIEELEK---ELESLEGSKRKLEEKIRELE 265
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 494 FRERNSKGQLEVMVHKLQ--NEIKKLTVELMKAKDQQEDHLKHLRTLEKTLEKMERQKRQQqaaqIRLIQEVELKASAAd 571
Cdd:PRK03918 266 ERIEELKKEIEELEEKVKelKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGI----EERIKELEEKEERL- 340
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 572 REIYLLRTSLHREREQAQQLHQLL--ALKEQEHRKELETREFFTDADFQDALAKEIAKEEKKHEQMIKEYQEKIDVLSQQ 649
Cdd:PRK03918 341 EELKKKLKELEKRLEELEERHELYeeAKAKKEELERLKKRLTGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKE 420
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 650 YMDLE---NEFRialtvEARRFQDVrIGTQLFIENRINLtcmVKEQKTKLAEVSKLKQETAAnlqnqintleilieddkq 726
Cdd:PRK03918 421 IKELKkaiEELK-----KAKGKCPV-CGRELTEEHRKEL---LEEYTAELKRIEKELKEIEE------------------ 473
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 727 ksiQIELLKHEKVQLISELAaKESLIFGLRterkvwghELAQQGSSLAQNRGKLEaqIESLSRENECLRKTNEsDSDALR 806
Cdd:PRK03918 474 ---KERKLRKELRELEKVLK-KESELIKLK--------ELAEQLKELEEKLKKYN--LEELEKKAEEYEKLKE-KLIKLK 538
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 807 IKCKIIDDQTETIRKLKDCLQEKDEHIKRLQEKITEIEKCTQEQLDEKSSQLDEVLEKLERHNERKEKLKQQLKGKEVEL 886
Cdd:PRK03918 539 GEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKELEPFYNEYLELKDAEKELEREE 618
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 887 EEIRKAYSTLNrkwhDKGELLCHLETQVKEVKEKFENKEKKLKAERDKSIELQKNAMEKLHSMDDAFKRQVDAIVEAHQA 966
Cdd:PRK03918 619 KELKKLEEELD----KAFEELAETEKRLEELRKELEELEKKYSEEEYEELREEYLELSRELAGLRAELEELEKRREEIKK 694
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|.
gi 1034661819 967 EIAQLANEKQKcIDSANLKVHQIEKeMRELLEETCKNKKTMEAKIKQLAFA 1017
Cdd:PRK03918 695 TLEKLKEELEE-REKAKKELEKLEK-ALERVEELREKVKKYKALLKERALS 743
|
|
| LRR_4 |
pfam12799 |
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a ... |
66-107 |
1.16e-05 |
|
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a number of proteins with diverse functions and cellular locations. These repeats are usually involved in protein-protein interactions. Each Leucine Rich Repeat is composed of a beta-alpha unit. These units form elongated non-globular structures. Leucine Rich Repeats are often flanked by cysteine rich domains.
Pssm-ID: 463713 [Multi-domain] Cd Length: 44 Bit Score: 43.39 E-value: 1.16e-05
10 20 30 40
....*....|....*....|....*....|....*....|...
gi 1034661819 66 NLQHLDLSSNQISRIEGLNTLTKLCTLNLS-CNLITKVEGLEE 107
Cdd:pfam12799 2 NLEVLDLSNNQITDIPPLAKLPNLETLDLSgNNKITDLSDLAN 44
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
779-997 |
1.35e-05 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 49.53 E-value: 1.35e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 779 KLEAQIESLSRenecLRKTNEsDSDALRIKCKIIDD---------QTETIRKLKDCLQEKDEHIKRLQEKITEIEkctqE 849
Cdd:COG4913 246 DAREQIELLEP----IRELAE-RYAAARERLAELEYlraalrlwfAQRRLELLEAELEELRAELARLEAELERLE----A 316
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 850 QLDEKSSQLDEVLEKLERH-NERKEKLKQQLKGKEVELEEIRKAYSTLNrkwhdkgELLCHLETQVKEVKEKFENKEKKL 928
Cdd:COG4913 317 RLDALREELDELEAQIRGNgGDRLEQLEREIERLERELEERERRRARLE-------ALLAALGLPLPASAEEFAALRAEA 389
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1034661819 929 KAERDKSIELQKNAMEKLHSMDDAFKRQVDAIvEAHQAEIAQLANeKQKCIDSanlKVHQIEKEMRELL 997
Cdd:COG4913 390 AALLEALEEELEALEEALAEAEAALRDLRREL-RELEAEIASLER-RKSNIPA---RLLALRDALAEAL 453
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
697-899 |
1.88e-05 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 48.22 E-value: 1.88e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 697 AEVSKLKQETAANLQNQINTLEILIEDDKQksiQIELLKHEKVQLISELAAKESLIFGLRTERKVWGHELAQQGSSLAQN 776
Cdd:COG4942 19 ADAAAEAEAELEQLQQEIAELEKELAALKK---EEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAEL 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 777 RGKLEAQIESLSRENECLRKTNESDSDALRIKCKIIDDQTETIRKLKDCLQEKDEHIKRLQEKITEIEKcTQEQLDEKSS 856
Cdd:COG4942 96 RAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAA-LRAELEAERA 174
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 1034661819 857 QLDEVLEKLErhnERKEKLKQQLKGKEVELEEIRKAYSTLNRK 899
Cdd:COG4942 175 ELEALLAELE---EERAALEALKAERQKLLARLEKELAELAAE 214
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
30-148 |
2.18e-05 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 48.25 E-value: 2.18e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 30 DKGLQSISE-LSLDSTLHAVNLHCNNISK------IEAIDHIWNLQHLDLSSNQISR------IEGLNTLTKLCTLNLSC 96
Cdd:COG5238 194 DEGIEELAEaLTQNTTVTTLWLKRNPIGDegaeilAEALKGNKSLTTLDLSNNQIGDegvialAEALKNNTTVETLYLSG 273
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 97 NLITK------VEGLEELINLTRLNVSYNHIDDLS--GLIPLHGIKHKLRYIDLHSNRID 148
Cdd:COG5238 274 NQIGAegaialAKALQGNTTLTSLDLSVNRIGDEGaiALAEGLQGNKTLHTLNLAYNGIG 333
|
|
| LRR_9 |
pfam14580 |
Leucine-rich repeat; |
70-145 |
2.50e-05 |
|
Leucine-rich repeat;
Pssm-ID: 405295 [Multi-domain] Cd Length: 175 Bit Score: 45.91 E-value: 2.50e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1034661819 70 LDLSSNQISRIEGLNTLTKLCTLNLSCNLITKV-EGLEELI-NLTRLNVSYNHIDDLSGLIPLHGIKhKLRYIDLHSN 145
Cdd:pfam14580 47 IDFSDNEIRKLDGFPLLRRLKTLLLNNNRICRIgEGLGEALpNLTELILTNNNLQELGDLDPLASLK-KLTFLSLLRN 123
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
66-147 |
3.09e-05 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 42.51 E-value: 3.09e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 66 NLQHLDLSSNQISRIEG--LNTLTKLCTLNLSCNLITKVEGleelinltrlnvsynhiDDLSGLiplhgikHKLRYIDLH 143
Cdd:pfam13855 2 NLRSLDLSNNRLTSLDDgaFKGLSNLKVLDLSNNLLTTLSP-----------------GAFSGL-------PSLRYLDLS 57
|
....
gi 1034661819 144 SNRI 147
Cdd:pfam13855 58 GNRL 61
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
438-1000 |
3.36e-05 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 48.01 E-value: 3.36e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 438 QSLVEQLDQEREKRWRAEQAENKLMDYIDELHKHANEKEDIHSLALLTTDRLKEIIFRERNSKGQLEVMVHKLQNEIKKL 517
Cdd:COG1196 263 AELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEEL 342
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 518 TVELMKAKDQQEDHLKHLRTLEKTL----EKMERQKRQQQAAQIRLIQEVELKASAADREIYLLRTSLHREREQAQQLHQ 593
Cdd:COG1196 343 EEELEEAEEELEEAEAELAEAEEALleaeAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEE 422
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 594 LLALKEQEHRKELETREFFTDADFQDALAKEIAKEEKKHEQMIKEYQEKIDVLSQQYMDLENEF-----RIALTVEARRF 668
Cdd:COG1196 423 LEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELaeaaaRLLLLLEAEAD 502
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 669 QDVRIGTQLFIENRINLtCMVKEQKTKLAEVSKlKQETAANLQNQINTLEILIEDDKQKSIQIELLKHEK--------VQ 740
Cdd:COG1196 503 YEGFLEGVKAALLLAGL-RGLAGAVAVLIGVEA-AYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKagratflpLD 580
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 741 LISELAAKESLIFGLRTERKVWGHE-LAQQGSSLAQNRGKLEAQIESLSRENECLRKTNESDSDALRIKCKIIDDQTETI 819
Cdd:COG1196 581 KIRARAALAAALARGAIGAAVDLVAsDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGG 660
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 820 RKLKDCLQEKDEHIKRLQEKITEIEKCTQEQLDEKSSQLDEVLEKLERHNERKEKLKQQLKGKEVELEEIRKAYSTLNRK 899
Cdd:COG1196 661 SLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEE 740
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 900 WHDKGELLchletqvkevkekfeNKEKKLKAERDKSIELQKNAMEKLhsmddafKRQVD--------AIVEAHQAE---- 967
Cdd:COG1196 741 LLEEEELL---------------EEEALEELPEPPDLEELERELERL-------EREIEalgpvnllAIEEYEELEeryd 798
|
570 580 590
....*....|....*....|....*....|....*...
gi 1034661819 968 -----IAQLANEKQKcIDSAnlkVHQIEKEMRELLEET 1000
Cdd:COG1196 799 flseqREDLEEARET-LEEA---IEEIDRETRERFLET 832
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
523-896 |
4.08e-05 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 47.81 E-value: 4.08e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 523 KAKDQQEDHLKHLRTLEKTLEKMERQKRQQQAAQIRLIQEVELKASAADREIYLLRTslhrEREQ--------AQQLHQL 594
Cdd:pfam15921 307 QARNQNSMYMRQLSDLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEART----ERDQfsqesgnlDDQLQKL 382
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 595 LA---LKEQEHRKELETREFFTDADFQ-----DALAKEIAK---EEKKHEQMIKEYQEKIDVLSQQYM--------DLEN 655
Cdd:pfam15921 383 LAdlhKREKELSLEKEQNKRLWDRDTGnsitiDHLRRELDDrnmEVQRLEALLKAMKSECQGQMERQMaaiqgkneSLEK 462
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 656 EFRIALTVEA-----RRFQDVRIGTQLFIENR----INLTCMVKEQKTKL----AEVSKLKQETAANLQnQINTLEilIE 722
Cdd:pfam15921 463 VSSLTAQLEStkemlRKVVEELTAKKMTLESSertvSDLTASLQEKERAIeatnAEITKLRSRVDLKLQ-ELQHLK--NE 539
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 723 DDKQKSIQIELlkhEKVQLisELAAKESLIFGLRTERKVWGHELAQQG---SSLAQNRGKLEAQIESL-----------S 788
Cdd:pfam15921 540 GDHLRNVQTEC---EALKL--QMAEKDKVIEILRQQIENMTQLVGQHGrtaGAMQVEKAQLEKEINDRrlelqefkilkD 614
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 789 RENECLRKTNESDSDALRIKCKIIDDQTETIRKLKDCLQEKDEHIKRLQEKITEIEKCTQEQldekssqldEVLE----- 863
Cdd:pfam15921 615 KKDAKIRELEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDY---------EVLKrnfrn 685
|
410 420 430
....*....|....*....|....*....|...
gi 1034661819 864 KLERHNERKEKLKQQLKGKEVELEEIRKAYSTL 896
Cdd:pfam15921 686 KSEEMETTTNKLKMQLKSAQSELEQTRNTLKSM 718
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
32-148 |
6.95e-05 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 46.71 E-value: 6.95e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 32 GLQSISELSLDSTLHAVNLHCNNISKiEAIDHIW-------NLQHLDLSSNQI------SRIEGLNTLTKLCTLNLSCNL 98
Cdd:COG5238 169 AAISMAKALQNNSVETVYLGCNQIGD-EGIEELAealtqntTVTTLWLKRNPIgdegaeILAEALKGNKSLTTLDLSNNQ 247
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 99 ITKvEGLEELI-------NLTRLNVSYNHIDD--LSGLIP-LHGIKHkLRYIDLHSNRID 148
Cdd:COG5238 248 IGD-EGVIALAealknntTVETLYLSGNQIGAegAIALAKaLQGNTT-LTSLDLSVNRIG 305
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
498-728 |
8.80e-05 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 45.91 E-value: 8.80e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 498 NSKGQLEVMVHKLQNEIKKLTVELMKAKDQQEDHLKHLRTLEKTLEKMErqkrqqqaaqiRLIQEVELKASAADREIYLL 577
Cdd:COG4942 20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALA-----------RRIRALEQELAALEAELAEL 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 578 RTSLHREREQAQQLHQLLA--------LKEQEHRKELETREFFTDADFQDALAKEIAKEEKkheQMIKEYQEKIDVLSQQ 649
Cdd:COG4942 89 EKEIAELRAELEAQKEELAellralyrLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARR---EQAEELRADLAELAAL 165
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1034661819 650 YMDLENEFRIALTVEARRFQDVRIGTQLFIENRINLTCMVKEQKTKLAEVSKLKQEtAANLQNQINTLEILIEDDKQKS 728
Cdd:COG4942 166 RAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQE-AEELEALIARLEAEAAAAAERT 243
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
690-899 |
1.12e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 45.53 E-value: 1.12e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 690 KEQKTKLAEVSKLKQETAANLQNQINTLEILIEDDKQKSIQIELLKHEKVQLISELAAKESLIFGLRTErkvwgheLAQQ 769
Cdd:COG4942 23 AEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKE-------IAEL 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 770 GSSLAQNRGKLEAQIESLSRENEC----LRKTNESDSDALRIK------CKIIDDQTETIRKLKDCLQEKDEHIKRLQEK 839
Cdd:COG4942 96 RAELEAQKEELAELLRALYRLGRQpplaLLLSPEDFLDAVRRLqylkylAPARREQAEELRADLAELAALRAELEAERAE 175
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 840 ITEIEKCTQEQLDEKSSQLDEVLEKLERHNERKEKLKQQLKGKEVELEEIRKAYSTLNRK 899
Cdd:COG4942 176 LEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAE 235
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
848-1025 |
1.14e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 45.53 E-value: 1.14e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 848 QEQLDEKSSQLDEVLEKLERHNERKEKLKQQLKGKEVELEEIRKAYSTLNRKWHDKGELLCHLETQVKEVKEKFENKEKK 927
Cdd:COG4942 19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 928 LKAERDKsIELQKNAMEKLH------------SMDDAFKRQ--VDAIVEAHQAEIAQLANEKQKcIDSANLKVHQIEKEM 993
Cdd:COG4942 99 LEAQKEE-LAELLRALYRLGrqpplalllspeDFLDAVRRLqyLKYLAPARREQAEELRADLAE-LAALRAELEAERAEL 176
|
170 180 190
....*....|....*....|....*....|..
gi 1034661819 994 RELLEETCKNKKTMEAKIKQLAFALNEIQQDM 1025
Cdd:COG4942 177 EALLAELEEERAALEALKAERQKLLARLEKEL 208
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
43-123 |
1.55e-04 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 45.55 E-value: 1.55e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 43 STLHAVNLHCNNISKIEAI---DHIW---NLQHLDLSSNQISR------IEGLNTLTKLCTLNLSCNLITKvEGLEELI- 109
Cdd:COG5238 320 KTLHTLNLAYNGIGAQGAIalaKALQentTLHSLDLSDNQIGDegaialAKYLEGNTTLRELNLGKNNIGK-QGAEALId 398
|
90
....*....|....*....
gi 1034661819 110 -----NLTRLNVSYNHIDD 123
Cdd:COG5238 399 alqtnRLHTLILDGNLIGA 417
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
489-916 |
1.67e-04 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 45.78 E-value: 1.67e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 489 LKEIIFRERNSKGQLEVMVHKLQNEIKKLTVELMKAKDQQEDHLKHLRTLEKTLEKMERQKRQQQAAQIRL--------I 560
Cdd:TIGR04523 230 LKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLnnqkeqdwN 309
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 561 QEVELKASAADREIYLLRTSLHREREQAQQLHQLLA-LKEQEHRKELETREfftdadfqdaLAKEIAKEEKKHEQMIKE- 638
Cdd:TIGR04523 310 KELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISqLKKELTNSESENSE----------KQRELEEKQNEIEKLKKEn 379
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 639 --YQEKIDVLSQQYMDLENEFRIALTVEARRFQDVRIGTQ--LFIENRINLtcmVKEQKTKLAEVSKLKQETAANLQNQI 714
Cdd:TIGR04523 380 qsYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQekELLEKEIER---LKETIIKNNSEIKDLTNQDSVKELII 456
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 715 NTLEILIEDDKQK----SIQIELLKHEKVQLISELAAKESLIFGLRTERKvwghELAQQGSSLAQNRGKLEAQIESLsrE 790
Cdd:TIGR04523 457 KNLDNTRESLETQlkvlSRSINKIKQNLEQKQKELKSKEKELKKLNEEKK----ELEEKVKDLTKKISSLKEKIEKL--E 530
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 791 NECLRKTNESDSdalrIKCKII-DDQTETIRKLKDCLQEKDEHIKRLQEKITEIEKCT---QEQLDEKSSQLDEVLEKLE 866
Cdd:TIGR04523 531 SEKKEKESKISD----LEDELNkDDFELKKENLEKEIDEKNKEIEELKQTQKSLKKKQeekQELIDQKEKEKKDLIKEIE 606
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|
gi 1034661819 867 RHNERKEKLKQQLKGKEVELEEIRKAYSTLNRKWHDKGELLCHLETQVKE 916
Cdd:TIGR04523 607 EKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKE 656
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
415-761 |
1.87e-04 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 45.90 E-value: 1.87e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 415 QESEKPKTEIIKVDQSHSEDNTYQSLVEQLDQEREKRWRAEQAENKLMDYIDELHKHANEKEDIHSLallttdRLKEIIF 494
Cdd:PTZ00121 1473 DEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEA------KKAEEKK 1546
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 495 RERNSKGQLEVmvhKLQNEIKKLTvelmKAKDQQEDHLKHLRTLEKtLEKMERQKRQQQAAQIRLIQEVELKASAADREI 574
Cdd:PTZ00121 1547 KADELKKAEEL---KKAEEKKKAE----EAKKAEEDKNMALRKAEE-AKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEA 1618
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 575 YLLRTSLHREREQAQQLHQLLALKEQEHRKELETREFFTDADFQDALAKEIAKEEKKHEQMIKEYQEKIDVLSQQYMDLE 654
Cdd:PTZ00121 1619 KIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEA 1698
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 655 NEFRIALTVEARRFQDVRIGTQLFIENRINLtcMVKEQKTKLAEVSKLKQETAANLQNQINTLEILIEDDKQKSiqiELL 734
Cdd:PTZ00121 1699 EEAKKAEELKKKEAEEKKKAEELKKAEEENK--IKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKA---EEI 1773
|
330 340
....*....|....*....|....*..
gi 1034661819 735 KHEKVQLISELAAKESLIFGLRTERKV 761
Cdd:PTZ00121 1774 RKEKEAVIEEELDEEDEKRRMEVDKKI 1800
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
441-999 |
2.62e-04 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 45.29 E-value: 2.62e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 441 VEQLDQEREKRWRAEQAENKLmDYIDELHKHANEKEDIHSLALLTT--DRLKEIIFRERNSKGQLEVMVHKLQNEIKKLT 518
Cdd:COG4913 251 IELLEPIRELAERYAAARERL-AELEYLRAALRLWFAQRRLELLEAelEELRAELARLEAELERLEARLDALREELDELE 329
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 519 VELMKAKDQQEDHLKH-LRTLEKTLEKMERQKRQQQAAQIRLiqEVELKASAAD-----REIYLLRTSLHREREQAQQLH 592
Cdd:COG4913 330 AQIRGNGGDRLEQLEReIERLERELEERERRRARLEALLAAL--GLPLPASAEEfaalrAEAAALLEALEEELEALEEAL 407
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 593 QLLALKEQEHRKELetrefftdadfqDALAKEIAKEEKKHEQMIKEYQEKIDVLSQQ-------------YMDLENE--- 656
Cdd:COG4913 408 AEAEAALRDLRREL------------RELEAEIASLERRKSNIPARLLALRDALAEAlgldeaelpfvgeLIEVRPEeer 475
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 657 -----------FRIALTVEARRFQDVRigtqLFIENRinltcmvkeqktklaevsklkqetaaNLQNQINTLEILIEDDK 725
Cdd:COG4913 476 wrgaiervlggFALTLLVPPEHYAAAL----RWVNRL--------------------------HLRGRLVYERVRTGLPD 525
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 726 QKSIQIEllkheKVQLISELAAKESLIFG-LRTE-RKVWGH-------ELAQQGSSL------AQNRGKLEAQIESLSRE 790
Cdd:COG4913 526 PERPRLD-----PDSLAGKLDFKPHPFRAwLEAElGRRFDYvcvdspeELRRHPRAItragqvKGNGTRHEKDDRRRIRS 600
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 791 NECLRKTNESDSDALRikcKIIDDQTETIRKLKDCLQEKDEHIKRLQEKITEIEKCTQ--------EQLDEKSSQLDEVL 862
Cdd:COG4913 601 RYVLGFDNRAKLAALE---AELAELEEELAEAEERLEALEAELDALQERREALQRLAEyswdeidvASAEREIAELEAEL 677
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 863 EKLERHNERKEKLKQQLKGKEVELEEIRKAYSTLNRKwhdKGELlchletqvkevkekfenkekklKAERDKSIELQKNA 942
Cdd:COG4913 678 ERLDASSDDLAALEEQLEELEAELEELEEELDELKGE---IGRL----------------------EKELEQAEEELDEL 732
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1034661819 943 MEKLHSMDDAFKRQVDAIVEAHQAEIAQLANEK------QKCIDSANLKVHQIEKEMRELLEE 999
Cdd:COG4913 733 QDRLEAAEDLARLELRALLEERFAAALGDAVERelrenlEERIDALRARLNRAEEELERAMRA 795
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
426-1020 |
3.62e-04 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 44.52 E-value: 3.62e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 426 KVDQSHSEDNTYQSLVEQLDQEREKRwRAEQAENKLMDYIDELHKHANEKEDIHSLALLTTDRLKEIIFRERNSKGQLev 505
Cdd:COG4913 263 RYAAARERLAELEYLRAALRLWFAQR-RLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGGDR-- 339
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 506 mVHKLQNEIKKLTVELMKAKDQQEDHLKHLRTLEKTLEKMERQKRQQQAAQIRLIQEVELKASAADREIYLLRTSLHRER 585
Cdd:COG4913 340 -LEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLR 418
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 586 EQAQQLHQLLAlkeqehrkELETREFFTDADFQDALAkEIAKEEKKHEQMIKEYQEKIDVLSqqymdlENE--------- 656
Cdd:COG4913 419 RELRELEAEIA--------SLERRKSNIPARLLALRD-ALAEALGLDEAELPFVGELIEVRP------EEErwrgaierv 483
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 657 ---FRIALTVEARRFQDV-RIGTQLFIENRINL----TCMVKEQKTKLAE---VSKLkqETAAN-----LQNQIN----- 715
Cdd:COG4913 484 lggFALTLLVPPEHYAAAlRWVNRLHLRGRLVYervrTGLPDPERPRLDPdslAGKL--DFKPHpfrawLEAELGrrfdy 561
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 716 ----TLEILieDDKQKSIQIE-LLKHEKV--QLISELAAKESLIFGLRTERKVwgHELAQQGSSLAQNRGKLEAQIESLS 788
Cdd:COG4913 562 vcvdSPEEL--RRHPRAITRAgQVKGNGTrhEKDDRRRIRSRYVLGFDNRAKL--AALEAELAELEEELAEAEERLEALE 637
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 789 REneclRKTNESDSDALRikcKIIDDQTETIRklkdcLQEKDEHIKRLQEKITEIEKcTQEQLDEKSSQLDEVLEKLERH 868
Cdd:COG4913 638 AE----LDALQERREALQ---RLAEYSWDEID-----VASAEREIAELEAELERLDA-SSDDLAALEEQLEELEAELEEL 704
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 869 NERKEKLKQQLKGKEVELEEIRKAYSTLNRKWHDKGELLC-----HLETQVKEVKEKFENKEKKLK--AERDKSIELQKN 941
Cdd:COG4913 705 EEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARlelraLLEERFAAALGDAVERELRENleERIDALRARLNR 784
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1034661819 942 AMEKLHSMDDAFKRQVDAIVEAHQAEIAQLANEKQKCIDSANLKVHQIEKEMRELLeetcknKKTMEAKIKQLAFALNE 1020
Cdd:COG4913 785 AEEELERAMRAFNREWPAETADLDADLESLPEYLALLDRLEEDGLPEYEERFKELL------NENSIEFVADLLSKLRR 857
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
422-890 |
3.77e-04 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 44.54 E-value: 3.77e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 422 TEIIKVDQSHSEDNtyQSLVEQLDQEREKRWRAEQAENKLMDYIDELHKHANEKEDIHSLALLTTDRLKEIIFRERNSKG 501
Cdd:COG1196 267 AELEELRLELEELE--LELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEE 344
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 502 QLEVMVHKLQNEIKKLTVELMKAKDQQEDHLKHLRTLEKTLEKMERQKRQQQAAQIRLIQEVELKASAADREIYLLRTSL 581
Cdd:COG1196 345 ELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELE 424
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 582 HREREQAQQLHQLLALKEQEHRKELETREFFTDADFQDALAKEIAKEEKKHEQMIKEYQEKIDVLSQQYMDLENefriAL 661
Cdd:COG1196 425 ELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLE----AE 500
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 662 TVEARRFQDVRIGTQLFIENRINLTCMVkEQKTKLAEVSKLKQETAANLQNqintleILIEDDKQKSIQIELLKHEK--- 738
Cdd:COG1196 501 ADYEGFLEGVKAALLLAGLRGLAGAVAV-LIGVEAAYEAALEAALAAALQN------IVVEDDEVAAAAIEYLKAAKagr 573
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 739 -----VQLISELAAKESLIFGLRTERKVWGHE-LAQQGSSLAQNRGKLEAQIESLSRENECLRKTNESDSDALRIKCKII 812
Cdd:COG1196 574 atflpLDKIRARAALAAALARGAIGAAVDLVAsDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEG 653
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1034661819 813 DDQTETIRKLKDCLQEKDEHIKRLQEKITEIEKCTQEQLDEKSSQLDEVLEKLERHNERKEKLKQQLKGKEVELEEIR 890
Cdd:COG1196 654 EGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLE 731
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
779-976 |
4.16e-04 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 44.37 E-value: 4.16e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 779 KLEAQIESLSRENECLRKTNESDSDALRIKCKIIDDQTETIRKLKDCLQEKDEHIKRLQEKIteiekctqEQLDEKSSQL 858
Cdd:COG4717 50 RLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAEL--------EELREELEKL 121
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 859 DEVLEKLERHNERKEkLKQQLKGKEVELEEIRKAYstlnRKWHDKGELLCHLETQVKEVKEKFENKEKKLKAERDKSIEL 938
Cdd:COG4717 122 EKLLQLLPLYQELEA-LEAELAELPERLEELEERL----EELRELEEELEELEAELAELQEELEELLEQLSLATEEELQD 196
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 1034661819 939 QKNAMEKLHSMDDAFKRQVDAI---VEAHQAEIAQLANEKQ 976
Cdd:COG4717 197 LAEELEELQQRLAELEEELEEAqeeLEELEEELEQLENELE 237
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
767-977 |
4.88e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 43.60 E-value: 4.88e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 767 AQQGSSLAQNRGKLEAQIESLSRENECLRKTNESDSDALRIKCKIIDDQTETIRKLKDCLQEKDEHIKRLQEKITEIEKc 846
Cdd:COG4942 19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRA- 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 847 tqeQLDEKSSQLDEVLEKLERhNERKEKLKQQLKGKEV-ELEEIRKAYSTLNRKWHDKGELLCHLETQVKEVKEKFENKE 925
Cdd:COG4942 98 ---ELEAQKEELAELLRALYR-LGRQPPLALLLSPEDFlDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAER 173
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 1034661819 926 KKLKAERDKsIELQKNAMEKLHSMDDAFKRQVDAIVEAHQAEIAQLANEKQK 977
Cdd:COG4942 174 AELEALLAE-LEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEE 224
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
415-891 |
4.94e-04 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 44.36 E-value: 4.94e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 415 QESEKPKTEIIKVDQSHSEDNTYQSLVEQLDQEREKRWRAEQAENKLMDY--IDELHKHANEKEDIHSLALLTTDRLK-E 491
Cdd:PTZ00121 1381 DAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKkkADEAKKKAEEAKKADEAKKKAEEAKKaE 1460
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 492 IIFRERNSKGQLEVMvhKLQNEIKKLTVELMKAKDQQEDHLKHLRTLEKTLEKMErqkrqqqaaqirliqevELKASAAD 571
Cdd:PTZ00121 1461 EAKKKAEEAKKADEA--KKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKAD-----------------EAKKAEEA 1521
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 572 REIYLLRTSlhREREQAQQLHqllalKEQEHRKELETREfftdadfqdalAKEI--AKEEKKHEQMIKEYQEKIDVLSQQ 649
Cdd:PTZ00121 1522 KKADEAKKA--EEAKKADEAK-----KAEEKKKADELKK-----------AEELkkAEEKKKAEEAKKAEEDKNMALRKA 1583
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 650 ymdlenefRIALTVEARRFQDVrigTQLFIENRinltcMVKEQKTKLAEVSKLKQETAANLqnqintleiliEDDKQKSI 729
Cdd:PTZ00121 1584 --------EEAKKAEEARIEEV---MKLYEEEK-----KMKAEEAKKAEEAKIKAEELKKA-----------EEEKKKVE 1636
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 730 QIELLKHEKVQLISELAAKESlifglrtERKVWGHELAQQGsslaqnrgkleaqiESLSRENECLRKTNESDsdalRIKC 809
Cdd:PTZ00121 1637 QLKKKEAEEKKKAEELKKAEE-------ENKIKAAEEAKKA--------------EEDKKKAEEAKKAEEDE----KKAA 1691
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 810 KIIDDQTETIRKLKDCLQEKDEHIKRLQE--KITEIEKCTQEQLDEKSSQLDEVLEKLERHNERKEKLKQQLKGKEVELE 887
Cdd:PTZ00121 1692 EALKKEAEEAKKAEELKKKEAEEKKKAEElkKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAE 1771
|
....
gi 1034661819 888 EIRK 891
Cdd:PTZ00121 1772 EIRK 1775
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
777-891 |
5.48e-04 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 43.61 E-value: 5.48e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 777 RGKLEAQIESLSRENECLRKtnESDSDALRIKCKIIDDQTETIRKLKDCLQ----EKDEHIKRLQEKITEIEkctqEQLD 852
Cdd:PRK12704 26 KKIAEAKIKEAEEEAKRILE--EAKKEAEAIKKEALLEAKEEIHKLRNEFEkelrERRNELQKLEKRLLQKE----ENLD 99
|
90 100 110
....*....|....*....|....*....|....*....
gi 1034661819 853 EKSSQLDEVLEKLERHNERKEKLKQQLKGKEVELEEIRK 891
Cdd:PRK12704 100 RKLELLEKREEELEKKEKELEQKQQELEKKEEELEELIE 138
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
482-1025 |
5.75e-04 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 43.90 E-value: 5.75e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 482 ALLTTDRLKEIIFRERNSKGQLEVMVHKLQN---EIKKLTVELMKAKDQQEDHLKHLRTLEKTLEKMERQKRQQQAAQIR 558
Cdd:PRK03918 139 AILESDESREKVVRQILGLDDYENAYKNLGEvikEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPE 218
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 559 LIQEVElKASAADREIYLLRTSLHREREQAQQLHQLLAlKEQEHRKELETRefftdadfqdalAKEIAKEEKKHEQMIKE 638
Cdd:PRK03918 219 LREELE-KLEKEVKELEELKEEIEELEKELESLEGSKR-KLEEKIRELEER------------IEELKKEIEELEEKVKE 284
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 639 YqEKIDVLSQQYMDLeNEFRIALTVEARRFQDVRIGTQLFIENRINLTCMVKEQKTKLAEVSKLKQETAANLqNQINTLE 718
Cdd:PRK03918 285 L-KELKEKAEEYIKL-SEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRL-EELEERH 361
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 719 ILIEDDKQKSIQIELLKHEKVQL-ISELAAKESLIFGLRTERKVWGHELAQQGSSLAQNRGKLEAQIESLSRENE----C 793
Cdd:PRK03918 362 ELYEEAKAKKEELERLKKRLTGLtPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGkcpvC 441
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 794 LRKTNESDsdalriKCKIIDDQTETIRKLKDCLQEKDEHIKRLQEKITEIEKC------------TQEQLDEKSSQLDEV 861
Cdd:PRK03918 442 GRELTEEH------RKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVlkkeseliklkeLAEQLKELEEKLKKY 515
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 862 -LEKLERHNERKEKLKQQLKGKEVE----------LEEIRKAYSTLNRKWHDKGELLCHLETQVKEVKEKFENKEKKLKA 930
Cdd:PRK03918 516 nLEELEKKAEEYEKLKEKLIKLKGEikslkkelekLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLK 595
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 931 E----RDKSIELqKNAMEKLHSMDDAFKRQVDAIVEAHQ--AEIAQLANEKQKCIDSANLKVHQIE-KEMRELLEETCKN 1003
Cdd:PRK03918 596 ElepfYNEYLEL-KDAEKELEREEKELKKLEEELDKAFEelAETEKRLEELRKELEELEKKYSEEEyEELREEYLELSRE 674
|
570 580
....*....|....*....|..
gi 1034661819 1004 KKTMEAKIKQLAFALNEIQQDM 1025
Cdd:PRK03918 675 LAGLRAELEELEKRREEIKKTL 696
|
|
| LRR_4 |
pfam12799 |
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a ... |
87-127 |
9.89e-04 |
|
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a number of proteins with diverse functions and cellular locations. These repeats are usually involved in protein-protein interactions. Each Leucine Rich Repeat is composed of a beta-alpha unit. These units form elongated non-globular structures. Leucine Rich Repeats are often flanked by cysteine rich domains.
Pssm-ID: 463713 [Multi-domain] Cd Length: 44 Bit Score: 38.00 E-value: 9.89e-04
10 20 30 40
....*....|....*....|....*....|....*....|..
gi 1034661819 87 TKLCTLNLSCNLITKVEGLEELINLTRLNVSYN-HIDDLSGL 127
Cdd:pfam12799 1 PNLEVLDLSNNQITDIPPLAKLPNLETLDLSGNnKITDLSDL 42
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
466-1023 |
1.29e-03 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 43.03 E-value: 1.29e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 466 DELHKHANEKEDIHSLALLTTDRLKEIIFRERNSKGQLEVMVHKLQNEIKKLTVELMKAKDQQEDHLKhlrTLEKTLEKM 545
Cdd:TIGR00618 155 AQFLKAKSKEKKELLMNLFPLDQYTQLALMEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQ---VLEKELKHL 231
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 546 ERQKRQQQAAQIRLIQEVELKASaadreiyllRTSLHREREQAQQLHQLLALKEQEHRKELETREFFTDADFQDALAKEI 625
Cdd:TIGR00618 232 REALQQTQQSHAYLTQKREAQEE---------QLKKQQLLKQLRARIEELRAQEAVLEETQERINRARKAAPLAAHIKAV 302
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 626 AKEEKKHEQMIKEYQEKIDVLSQQYMDLENEFRialtvearrfQDVRIGTQLFIENRINLTCMVKEQKTKLAEVSKLKQE 705
Cdd:TIGR00618 303 TQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVK----------QQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISC 372
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 706 TAANLQNQINTLEILIEDDKQKSiqiELLKHEKVQLISELAAKESLIFGLRTERKVWGHELAQQGSS---LAQNRGKLEA 782
Cdd:TIGR00618 373 QQHTLTQHIHTLQQQKTTLTQKL---QSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQqryAELCAAAITC 449
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 783 QIESLSRENECLRKTNES--DSDALRIKCKIIDDQTETIRKLKD-------------CLQEKDEHIKRLQEKITEIEKCT 847
Cdd:TIGR00618 450 TAQCEKLEKIHLQESAQSlkEREQQLQTKEQIHLQETRKKAVVLarllelqeepcplCGSCIHPNPARQDIDNPGPLTRR 529
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 848 QEQLDEKSSQLDEVLEKLERHNERKEKLKQQLKGKEvelEEIRKAYSTLNRKWHdkgELLCHLETQVKEVKEKFENKEKK 927
Cdd:TIGR00618 530 MQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQM---QEIQQSFSILTQCDN---RSKEDIPNLQNITVRLQDLTEKL 603
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 928 LKAERDKSIELQKNAMEKLHSMDDAFKRQVDAIVEAHQA--------EIAQLANEKQKcIDSANLKVHQIEKEMRELLEE 999
Cdd:TIGR00618 604 SEAEDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQELAlkltalhaLQLTLTQERVR-EHALSIRVLPKELLASRQLAL 682
|
570 580
....*....|....*....|....
gi 1034661819 1000 tcknkKTMEAKIKQLAFALNEIQQ 1023
Cdd:TIGR00618 683 -----QKMQSEKEQLTYWKEMLAQ 701
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
43-99 |
1.38e-03 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 37.89 E-value: 1.38e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1034661819 43 STLHAVNLHCNNISKI--EAIDHIWNLQHLDLSSNQISRIEG--LNTLTKLCTLNLSCNLI 99
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLddGAFKGLSNLKVLDLSNNLLTTLSPgaFSGLPSLRYLDLSGNRL 61
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
53-163 |
1.54e-03 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 42.23 E-value: 1.54e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 53 NNISKIEAIDHIWNLQHLDLSSNQISRIEGLNTLTKLCTLNLSCNlitkvEGLEELINLTRLNVSYNHIDDLSGLIPLHg 132
Cdd:COG4886 62 LSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGN-----EELSNLTNLESLDLSGNQLTDLPEELANL- 135
|
90 100 110
....*....|....*....|....*....|.
gi 1034661819 133 ikHKLRYIDLHSNRIDSIHHLLQCMVGLHFL 163
Cdd:COG4886 136 --TNLKELDLSNNQLTDLPEPLGNLTNLKSL 164
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
560-788 |
2.23e-03 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 41.74 E-value: 2.23e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 560 IQEVELKASAADREIYLLRTSLHREREQAQQLHQLLALKEQEhrkeletrefftdadfQDALAKEIAKEEKKheqmIKEY 639
Cdd:COG3883 25 LSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAE----------------IDKLQAEIAEAEAE----IEER 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 640 QEKI-DVLSQQYMDLENEFRIALTVEARRFQDvrigtqlFIENRINLTC-------MVKEQKTKLAEVSKLKQEtaanLQ 711
Cdd:COG3883 85 REELgERARALYRSGGSVSYLDVLLGSESFSD-------FLDRLSALSKiadadadLLEELKADKAELEAKKAE----LE 153
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1034661819 712 NQINTLEILIEDDKQKSIQIELLKHEKVQLISELAAKESLIFGLRTERKVWGHELAQQGSSLAQNRGKLEAQIESLS 788
Cdd:COG3883 154 AKLAELEALKAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAA 230
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
487-685 |
2.27e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 41.67 E-value: 2.27e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 487 DRLKEIIFRERNSKGQLEVMVHKLQNEIKKLTVELMKAKDQQEDHLKHLRTLEKTLEKMERQKRQQQAAQIRLIQ----- 561
Cdd:COG4942 37 AELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAELLRalyrl 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 562 ----EVELKASAAD-----REIYLLRTSLHREREQAQQLHQLLA-LKEQEHRKELETREFFTDADFQDALAKEIAKEEKK 631
Cdd:COG4942 117 grqpPLALLLSPEDfldavRRLQYLKYLAPARREQAEELRADLAeLAALRAELEAERAELEALLAELEEERAALEALKAE 196
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1034661819 632 HEQMI-------KEYQEKIDVLSQQYMDLENEfrIALTVEARRFQDVRIGTQLFIENRINL 685
Cdd:COG4942 197 RQKLLarlekelAELAAELAELQQEAEELEAL--IARLEAEAAAAAERTPAAGFAALKGKL 255
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
779-891 |
3.17e-03 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 41.38 E-value: 3.17e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 779 KLEAQIESLSRENECLRKT-NESDSDALRIKCKIIDDQTETIRKLKdclqeKDEHIKRLQEKIteiekctqEQLDEKSSQ 857
Cdd:COG2433 417 RLEEQVERLEAEVEELEAElEEKDERIERLERELSEARSEERREIR-----KDREISRLDREI--------ERLERELEE 483
|
90 100 110
....*....|....*....|....*....|....*
gi 1034661819 858 LDEVLEKLERHNER-KEKLKQQLKGKEVELEEIRK 891
Cdd:COG2433 484 ERERIEELKRKLERlKELWKLEHSGELVPVKVVEK 518
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
110-169 |
3.24e-03 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 36.73 E-value: 3.24e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 110 NLTRLNVSYNHIDDLSGLIPLHGikHKLRYIDLHSNRIDSIHhlLQCMVGLHFLTNLILE 169
Cdd:pfam13855 2 NLRSLDLSNNRLTSLDDGAFKGL--SNLKVLDLSNNLLTTLS--PGAFSGLPSLRYLDLS 57
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
679-888 |
3.97e-03 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 41.21 E-value: 3.97e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 679 IENRIN-LTCMVKEQKTKLAEVSKLKQETAANLQNQINTLEILIEDDKQKSIQIELLKHEKVQLISELAAKESLIFGLRT 757
Cdd:TIGR02169 700 IENRLDeLSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEE 779
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 758 ERKVWGHELAQQGssLAQNRGKLEAQIESLSRENECLRKTnESDSDALRIKCKIIDDQTETI-RKLKDCLQEKDEHIKRL 836
Cdd:TIGR02169 780 ALNDLEARLSHSR--IPEIQAELSKLEEEVSRIEARLREI-EQKLNRLTLEKEYLEKEIQELqEQRIDLKEQIKSIEKEI 856
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1034661819 837 QEKITEIEKcTQEQLDEKSS---QLDEVLEKLERHNERKEKLKQQLKGKEVELEE 888
Cdd:TIGR02169 857 ENLNGKKEE-LEEELEELEAalrDLESRLGDLKKERDELEAQLRELERKIEELEA 910
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
66-130 |
4.82e-03 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 40.99 E-value: 4.82e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1034661819 66 NLQHLDLSSNQISRI--EGLNTLTKLCTLNLSCNLITKV--EGLEELINLTRLNVSYNhidDLSGLIPL 130
Cdd:PLN00113 476 RLENLDLSRNQFSGAvpRKLGSLSELMQLKLSENKLSGEipDELSSCKKLVSLDLSHN---QLSGQIPA 541
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
705-909 |
4.92e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 41.05 E-value: 4.92e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 705 ETAANLQNQINTLEIL---IEDDKQksiQIELLKH--EKVQLISELAAKESLIFGLRTERKVWGHE-----LAQQGSSLA 774
Cdd:COG4913 225 EAADALVEHFDDLERAheaLEDARE---QIELLEPirELAERYAAARERLAELEYLRAALRLWFAQrrlelLEAELEELR 301
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 775 QNRGKLEAQIESLS--------RENECLRKTNESDSDAL-RIKcKIIDDQTETIRKLKDCLQEKDEHIKRLQEKI----- 840
Cdd:COG4913 302 AELARLEAELERLEarldalreELDELEAQIRGNGGDRLeQLE-REIERLERELEERERRRARLEALLAALGLPLpasae 380
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1034661819 841 --TEIEKCTQEQLDEKSSQLDEVLEKLERHNERKEKLKQQLKGKEVELEEIRKAYSTLNRKWHDKGELLCH 909
Cdd:COG4913 381 efAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALRDALAE 451
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
45-145 |
5.10e-03 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 40.42 E-value: 5.10e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 45 LHAVNLHCNNISKIEAID------HIWNLQHLDLSSNQISRiEGLNTL--------TKLCTLNLSCNLITKV------EG 104
Cdd:cd00116 195 LEVLDLNNNGLTDEGASAlaetlaSLKSLEVLNLGDNNLTD-AGAAALasallspnISLLTLSLSCNDITDDgakdlaEV 273
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 1034661819 105 LEELINLTRLNVSYNHI----DDLSGLIpLHGIKHKLRYIDLHSN 145
Cdd:cd00116 274 LAEKESLLELDLRGNKFgeegAQLLAES-LLEPGNELESLWVKDD 317
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
438-741 |
8.52e-03 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 40.05 E-value: 8.52e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 438 QSLVEQLDQEREKRWRAEQAENKLMDYIDELHKHANEKEDihslallttdRLKEIIFRERNSKGQLEvmvhKLQNEIKKL 517
Cdd:TIGR02169 684 EGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEK----------EIEQLEQEEEKLKERLE----ELEEDLSSL 749
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 518 TVELMKAKDQQEDHLKHLRTLEKTLEKMERQKRQQQAAQIR-LIQEVELKASAADREIYLLRTSLhREREQA-QQLHQLL 595
Cdd:TIGR02169 750 EQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHsRIPEIQAELSKLEEEVSRIEARL-REIEQKlNRLTLEK 828
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 596 ALKEQEHRKELETREFFTD--ADFQDALAKEIAKEEKKhEQMIKEYQEKIDVLSQQYMDLENEfRIALTVEARRfqdvri 673
Cdd:TIGR02169 829 EYLEKEIQELQEQRIDLKEqiKSIEKEIENLNGKKEEL-EEELEELEAALRDLESRLGDLKKE-RDELEAQLRE------ 900
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1034661819 674 gtqlfIENRINltcMVKEQKTKLAEVSKLKQETAANLQNQINTLEILIEDDkqKSIQIELLKHEKVQL 741
Cdd:TIGR02169 901 -----LERKIE---ELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGED--EEIPEEELSLEDVQA 958
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
765-1023 |
8.52e-03 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 40.11 E-value: 8.52e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 765 ELAQQGSSLAQNRGKLEAQIESLSRENECLRKTNESDsdalRIKCKIIDDQTETIRKLKDCLQEKDEHIKRLQ--EKITE 842
Cdd:pfam17380 286 ERQQQEKFEKMEQERLRQEKEEKAREVERRRKLEEAE----KARQAEMDRQAAIYAEQERMAMERERELERIRqeERKRE 361
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 843 IEKCTQEQLDEKSSQLDEvLEKLERHNERK-EKLKQqlkgkevELEEIRKAYSTLNRKWHDKGELLCHLETQVKEVKEKF 921
Cdd:pfam17380 362 LERIRQEEIAMEISRMRE-LERLQMERQQKnERVRQ-------ELEAARKVKILEEERQRKIQQQKVEMEQIRAEQEEAR 433
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034661819 922 ENKEKKLKAERDKSIE-LQKNAMEKLHSMDDAFKRQVDAIVEAHQAEIAQlanEKQKCIDSANLKVhqIEKEMRE----L 996
Cdd:pfam17380 434 QREVRRLEEERAREMErVRLEEQERQQQVERLRQQEEERKRKKLELEKEK---RDRKRAEEQRRKI--LEKELEErkqaM 508
|
250 260
....*....|....*....|....*..
gi 1034661819 997 LEETCKnKKTMEAKIKQLAFALNEIQQ 1023
Cdd:pfam17380 509 IEEERK-RKLLEKEMEERQKAIYEEER 534
|
|
| |
