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Conserved domains on  [gi|1034632655|ref|XP_016861679|]
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golgin subfamily B member 1 isoform X4 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1900-2772 2.71e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 92.81  E-value: 2.71e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1900 IQEELSRVTKLKETAEEEKDDLE------ERLMNQLAELNGSIGNYCQDVTDAQ----IKNELLESEMKNLKKCVSELEE 1969
Cdd:TIGR02168  160 IFEEAAGISKYKERRKETERKLErtrenlDRLEDILNELERQLKSLERQAEKAErykeLKAELRELELALLVLRLEELRE 239

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1970 EKQQLVKEKTKVESEIR------KEYLEKIQGAQKEPGNKSHAK-ELQELLKEKQQEVKQLQKDCIRYQEKISALERTVK 2042
Cdd:TIGR02168  240 ELEELQEELKEAEEELEeltaelQELEEKLEELRLEVSELEEEIeELQKELYALANEISRLEQQKQILRERLANLERQLE 319

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2043 ALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDdtqsEAARVLADNLKLKKELQSNKESVKS---QMKQKD 2119
Cdd:TIGR02168  320 ELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELE----ELEAELEELESRLEELEEQLETLRSkvaQLELQI 395

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2120 EDLERRLEQAEEkHLKEKKNMQEKLDALRRE--KVHLEETIGEIQVTLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQ 2197
Cdd:TIGR02168  396 ASLNNEIERLEA-RLERLEDRRERLQQEIEEllKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAE 474

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2198 DDRDRVIDEAKKWERKFsDAIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELkinISRLEHDKQiWESKAQTEVQ--LQQ 2275
Cdd:TIGR02168  475 QALDAAERELAQLQARL-DSLERLQENLEGFSEGVKALLKNQSGLSGILGVL---SELISVDEG-YEAAIEAALGgrLQA 549

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2276 KVCDTLQGENKELlsqleetrhlYHSSQNELAKLE-SELKSLKDQlTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSK-- 2352
Cdd:TIGR02168  550 VVVENLNAAKKAI----------AFLKQNELGRVTfLPLDSIKGT-EIQGNDREILKNIEGFLGVAKDLVKFDPKLRKal 618

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2353 ---FSYEQLETDLQASRELTSRLHEEINM--KEQKIIS---LLSGKEEAIQVAIAELRQqhdkEIKELENLLSQEEEENI 2424
Cdd:TIGR02168  619 sylLGGVLVVDDLDNALELAKKLRPGYRIvtLDGDLVRpggVITGGSAKTNSSILERRR----EIEELEEKIEELEEKIA 694

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2425 VLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERhlsiilekdqlIQEAAAEN 2504
Cdd:TIGR02168  695 ELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKE-----------LTELEAEI 763

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2505 NKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDSQQKQLlevqlqqnKELENKYAKLEEKLKESEEANED 2584
Cdd:TIGR02168  764 EELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAEL--------TLLNEEAANLRERLESLERRIAA 835

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2585 LRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTALQEEgtlglyhaqLKVKEEEVHRLSALFSSSQKRIAELEEELvcv 2664
Cdd:TIGR02168  836 TERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESE---------LEALLNERASLEEALALLRSELEELSEEL--- 903

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2665 qKEAAKKVGEIEDK---LKKELKHLHHDAGIMRNETETAEERVAELARDLVEM-EQKLLMVTKENKGLTAQIQSFGRSMS 2740
Cdd:TIGR02168  904 -RELESKRSELRREleeLREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEaEALENKIEDDEEEARRRLKRLENKIK 982

                          890       900       910
                   ....*....|....*....|....*....|..
gi 1034632655 2741 SLQNSRDHANEELDELKRKYDASLKELAQLKE 2772
Cdd:TIGR02168  983 ELGPVNLAAIEEYEELKERYDFLTAQKEDLTE 1014
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1352-2179 2.87e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 92.81  E-value: 2.87e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1352 IESLKTVSHEAEVHAEsLQQKLESSQLQIAGLEhLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQ 1431
Cdd:TIGR02168  202 LKSLERQAEKAERYKE-LKAELRELELALLVLR-LEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSEL 279

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1432 EDLIKALHTQLEMQAKEH---DERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEALKEnksLQEELSLA 1508
Cdd:TIGR02168  280 EEEIEELQKELYALANEIsrlEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEE---LKEELESL 356

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1509 RGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMdrsllenQSLSSSCESLKLALEGLTEDKEKLVKE 1588
Cdd:TIGR02168  357 EAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEI-------ERLEARLERLEDRRERLQQEIEELLKK 429

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1589 IESLKSSKIAESTEwqekhkELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEaeq 1668
Cdd:TIGR02168  430 LEEAELKELQAELE------ELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQEN--- 500

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1669 emeemkekmrkfAKSKQQKILELEEENDRLRAEVHPAGDtakecmetLLSSNASMKEELERVkmeyetLSKKFQSLMSEk 1748
Cdd:TIGR02168  501 ------------LEGFSEGVKALLKNQSGLSGILGVLSE--------LISVDEGYEAAIEAA------LGGRLQAVVVE- 553

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1749 dSLSEEVQDLKHQIEGNVSKQANLEATEKHDNQtnvteegtqsIPGETEEQDSLSMSTRPTCSESVPSAKSANPAVSkDF 1828
Cdd:TIGR02168  554 -NLNAAKKAIAFLKQNELGRVTFLPLDSIKGTE----------IQGNDREILKNIEGFLGVAKDLVKFDPKLRKALS-YL 621

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1829 SSH----DEINNYLQQIDQLK--ERIAGLEEEkQKNKEFSQTLENEKNTllSQISTKDGELKMLQEEVTKMNLLNQQIQE 1902
Cdd:TIGR02168  622 LGGvlvvDDLDNALELAKKLRpgYRIVTLDGD-LVRPGGVITGGSAKTN--SSILERRREIEELEEKIEELEEKIAELEK 698

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1903 ELSRVTKLKETAEEEKDDLEERlmnqLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVE 1982
Cdd:TIGR02168  699 ALAELRKELEELEEELEQLRKE----LEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAE 774

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1983 SEIrKEYLEKIQGAQKEPGN-KSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEfvqtesqKDLEITKEN 2061
Cdd:TIGR02168  775 EEL-AEAEAEIEELEAQIEQlKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATE-------RRLEDLEEQ 846

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2062 LAQAVEHRKKAQAELASFKVLLDDTQSEaarvLADNLKLKKELQSNKESVKSQMKQKDEDLerrleqaeekhlkekKNMQ 2141
Cdd:TIGR02168  847 IEELSEDIESLAAEIEELEELIEELESE----LEALLNERASLEEALALLRSELEELSEEL---------------RELE 907

                          810       820       830
                   ....*....|....*....|....*....|....*...
gi 1034632655 2142 EKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQENL 2179
Cdd:TIGR02168  908 SKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERL 945
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 758-1532 7.58e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 91.66  E-value: 7.58e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  758 VTELRAQVKQLEMNLAEAERQRRLdyesqtaHDNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQS 837
Cdd:TIGR02168  195 LNELERQLKSLERQAEKAERYKEL-------KAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEE 267

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  838 QLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISfsmtEKMVQLN 917
Cdd:TIGR02168  268 KLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELA----EELAELE 343

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  918 EEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEmspagqiskeeLQHEFDLLKKENEQRKRKLQAA 997
Cdd:TIGR02168  344 EKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQ-----------LELQIASLNNEIERLEARLERL 412

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  998 LINRKELLQRVSRLEEELANL-KDESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIYLKQTiSEKEVELQHIR 1076
Cdd:TIGR02168  413 EDRRERLQQEIEELLKKLEEAeLKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAA-ERELAQLQARL 491

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1077 KDLEEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEISENQ-----------AIIQKLITSNTDASDGDSVALVKE--- 1142
Cdd:TIGR02168  492 DSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEgyeaaieaalgGRLQAVVVENLNAAKKAIAFLKQNelg 571

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1143 TVVISPPCTGSSEHWKPELEEKI----------LALEKEKEQLQKKLQ---------EALTSRKAILKKAQEKER----- 1198
Cdd:TIGR02168  572 RVTFLPLDSIKGTEIQGNDREILkniegflgvaKDLVKFDPKLRKALSyllggvlvvDDLDNALELAKKLRPGYRivtld 651

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1199 -----------------------------HLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVRESidgklpS 1249
Cdd:TIGR02168  652 gdlvrpggvitggsaktnssilerrreieELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEEL------S 725

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1250 TDQQESCSSTPGLEEPLFKATEQHHTQPVLESNLcpdwpshseDASALQGGTSVAQIKAQLKEIEAEKVELELKV----- 1324
Cdd:TIGR02168  726 RQISALRKDLARLEAEVEQLEERIAQLSKELTEL---------EAEIEELEERLEEAEEELAEAEAEIEELEAQIeqlke 796

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1325 --SSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLEH--------LRELQPKLD 1394
Cdd:TIGR02168  797 elKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAeieeleelIEELESELE 876

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1395 ELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEmQAKEHDERIKQ------------LQVELCE 1462
Cdd:TIGR02168  877 ALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLA-QLELRLEGLEVridnlqerlseeYSLTLEE 955

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1034632655 1463 MKQKPEEIGEESRAKQQIQRKLQAALIS----RKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKE 1532
Cdd:TIGR02168  956 AEALENKIEDDEEEARRRLKRLENKIKElgpvNLAAIEEYEELKERYDFLTAQKEDLTEAKETLEEAIEEIDRE 1029
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 190-1018 3.62e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 82.80  E-value: 3.62e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  190 QQLQEKEEFISTLQAQLSQTQAEQAaqvvREKDARFETQVRLHEDELLQLVTQADVETEMQQKLRVLQRKLEEHEESLVG 269
Cdd:TIGR02168  213 ERYKELKAELRELELALLVLRLEEL----REELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQK 288

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  270 RaqvVDLLQQELTAAEQRNQILSQQLQQMEAEhntlRNTVETEREESKILLEKMELEVAERKLSFHNLQEEMHHLLEQFE 349
Cdd:TIGR02168  289 E---LYALANEISRLEQQKQILRERLANLERQ----LEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELE 361

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  350 QAGQAQAELESRYSALEQKHkaemeektshilslqktgQELQSACDALKDQNSKLlqdkNEQAVQSAQTIQQLEDQLQQK 429
Cdd:TIGR02168  362 ELEAELEELESRLEELEEQL------------------ETLRSKVAQLELQIASL----NNEIERLEARLERLEDRRERL 419

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  430 SKEISQFLNRLPLQQHETASQTSfpdvynEGTQAVTEENIASLQKRVVELENEKGALLLSSIELEELKAENEKLSSQITL 509
Cdd:TIGR02168  420 QQEIEELLKKLEEAELKELQAEL------EELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDS 493

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  510 LEA-QNRTGEADREVSEI---------------SIVDIANKRSSSAE----ESGQDVLENTFSQKHKELSVLLlemKEAQ 569
Cdd:TIGR02168  494 LERlQENLEGFSEGVKALlknqsglsgilgvlsELISVDEGYEAAIEaalgGRLQAVVVENLNAAKKAIAFLK---QNEL 570

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  570 EEIAFLKLQLQGKRAEEADHEVLdQKEMKQMEGEGIAPIKMKVFLEDTGQDFplmpneESSLPAVEKEQASTEHQSRTSE 649
Cdd:TIGR02168  571 GRVTFLPLDSIKGTEIQGNDREI-LKNIEGFLGVAKDLVKFDPKLRKALSYL------LGGVLVVDDLDNALELAKKLRP 643

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  650 EISLNDAGVELKS-----TKQDGDKSLSAvpdigQCHQDELERLKSQILELELNFHKAqeiyEKNLDEKAKEISNLNQLI 724
Cdd:TIGR02168  644 GYRIVTLDGDLVRpggviTGGSAKTNSSI-----LERRREIEELEEKIEELEEKIAEL----EKALAELRKELEELEEEL 714

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  725 EEFKKNADNNSSAFTALSEERDQLLSQVKELSmvtelrAQVKQLEMNLAEAERQRrldyesqtahdNLLTEQIHSLSIEA 804
Cdd:TIGR02168  715 EQLRKELEELSRQISALRKDLARLEAEVEQLE------ERIAQLSKELTELEAEI-----------EELEERLEEAEEEL 777

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  805 KSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEK 884
Cdd:TIGR02168  778 AEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESL 857

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  885 KRDVETLQQTIEEKDQQVTEISF---SMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQN 961
Cdd:TIGR02168  858 AAEIEELEELIEELESELEALLNeraSLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVR 937

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1034632655  962 YDEMspAGQISkEELQHEFDLLKKENEQRKRKLQaalinrkELLQRVSRLEEELANL 1018
Cdd:TIGR02168  938 IDNL--QERLS-EEYSLTLEEAEALENKIEDDEE-------EARRRLKRLENKIKEL 984
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2453-3186 2.41e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 73.55  E-value: 2.41e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2453 QQKAQLDSFVKSMSSLQNDRDRIVGDYQQLE---ERHLSIILEKDQLIQEA-------AAENNKLKEEIRGLRSHMDDLN 2522
Cdd:TIGR02168  236 ELREELEELQEELKEAEEELEELTAELQELEeklEELRLEVSELEEEIEELqkelyalANEISRLEQQKQILRERLANLE 315

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2523 SENAKLDAELIQYREDLNQVITIKDSQQKQLLEVQ------LQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEK 2596
Cdd:TIGR02168  316 RQLEELEAQLEELESKLDELAEELAELEEKLEELKeeleslEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQI 395

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2597 QDLSKEIESLKVSISQLTRQVTALQEE-----------------GTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEE 2659
Cdd:TIGR02168  396 ASLNNEIERLEARLERLEDRRERLQQEieellkkleeaelkelqAELEELEEELEELQEELERLEEALEELREELEEAEQ 475

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2660 ELVCVQKEAAKKVGEIED----------------KLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTK 2723
Cdd:TIGR02168  476 ALDAAERELAQLQARLDSlerlqenlegfsegvkALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQAVVVENL 555

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2724 ENKGLTAQIQ---SFGRSMSSLQNSRDHA-----NEELDELKRKYDASLKELAQLKEQglLNRERDALLSETAFSMNSTE 2795
Cdd:TIGR02168  556 NAAKKAIAFLkqnELGRVTFLPLDSIKGTeiqgnDREILKNIEGFLGVAKDLVKFDPK--LRKALSYLLGGVLVVDDLDN 633

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2796 ENSLSHLEKLNQQLLSKDEQLLHLSSQLedsYNQVQSFSKAMASLQNERDHLWNELEKFRkseegkqrsaaqpstspAEV 2875
Cdd:TIGR02168  634 ALELAKKLRPGYRIVTLDGDLVRPGGVI---TGGSAKTNSSILERRREIEELEEKIEELE-----------------EKI 693

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2876 QSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELHPLKAQLQEYQDKTkAFQIMQEELRQENLSWQHELHQLRMEK 2955
Cdd:TIGR02168  694 AELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQL-EERIAQLSKELTELEAEIEELEERLEE 772

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2956 SSWEIHERRMKEQYLMAisDKDQQLSHLQNLIRELRSSSSQTQPLKVQYQRQASpetsaspdGSQNLVYETELLRTQLND 3035
Cdd:TIGR02168  773 AEEELAEAEAEIEELEA--QIEQLKEELKALREALDELRAELTLLNEEAANLRE--------RLESLERRIAATERRLED 842

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 3036 SLKEIHQKELRIQQLNSNFSQLLEEKNTLSIQLCDTSQSLRENQQHYGDLLNHcavLEKQVQELQAVSKEKGPLNIDvap 3115
Cdd:TIGR02168  843 LEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSE---LEELSEELRELESKRSELRRE--- 916

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1034632655 3116 gapqekngvhRKSDPEELREPQQSFSEAQQQLCNTRQEVNELRKLLEEERDQRVAA-ENALSVAEEQIRRLE 3186
Cdd:TIGR02168  917 ----------LEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKiEDDEEEARRRLKRLE 978
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 46-301 9.82e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 44.93  E-value: 9.82e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655   46 TQEDVQERLAYAEQLVVELKDIIRQKDVQLQQKDEALQEERKAADNKIKKLKLHAKAKLTSLNKYIEEMKAQGGTVLPTE 125
Cdd:COG1196    271 ELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAE 350

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  126 PQSEEQLSKHDKSSTEEEMEIEKIKHKLQEKEELISTLQAQLTQAQAEQPAQsstemeefvmmkQQLQEKEEFISTLQAQ 205
Cdd:COG1196    351 EELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQL------------EELEEAEEALLERLER 418

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  206 LSQTQAEQAAQVVREKDARfetqvrlhEDELLQLVTQADVETEMQQKLRVLQRKLEEHEESLVGRAQVVDLLQQELTAAE 285
Cdd:COG1196    419 LEEELEELEEALAELEEEE--------EEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAA 490

                          250
                   ....*....|....*.
gi 1034632655  286 QRNQILSQQLQQMEAE 301
Cdd:COG1196    491 ARLLLLLEAEADYEGF 506
 
Name Accession Description Interval E-value
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1900-2772 2.71e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 92.81  E-value: 2.71e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1900 IQEELSRVTKLKETAEEEKDDLE------ERLMNQLAELNGSIGNYCQDVTDAQ----IKNELLESEMKNLKKCVSELEE 1969
Cdd:TIGR02168  160 IFEEAAGISKYKERRKETERKLErtrenlDRLEDILNELERQLKSLERQAEKAErykeLKAELRELELALLVLRLEELRE 239

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1970 EKQQLVKEKTKVESEIR------KEYLEKIQGAQKEPGNKSHAK-ELQELLKEKQQEVKQLQKDCIRYQEKISALERTVK 2042
Cdd:TIGR02168  240 ELEELQEELKEAEEELEeltaelQELEEKLEELRLEVSELEEEIeELQKELYALANEISRLEQQKQILRERLANLERQLE 319

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2043 ALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDdtqsEAARVLADNLKLKKELQSNKESVKS---QMKQKD 2119
Cdd:TIGR02168  320 ELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELE----ELEAELEELESRLEELEEQLETLRSkvaQLELQI 395

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2120 EDLERRLEQAEEkHLKEKKNMQEKLDALRRE--KVHLEETIGEIQVTLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQ 2197
Cdd:TIGR02168  396 ASLNNEIERLEA-RLERLEDRRERLQQEIEEllKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAE 474

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2198 DDRDRVIDEAKKWERKFsDAIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELkinISRLEHDKQiWESKAQTEVQ--LQQ 2275
Cdd:TIGR02168  475 QALDAAERELAQLQARL-DSLERLQENLEGFSEGVKALLKNQSGLSGILGVL---SELISVDEG-YEAAIEAALGgrLQA 549

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2276 KVCDTLQGENKELlsqleetrhlYHSSQNELAKLE-SELKSLKDQlTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSK-- 2352
Cdd:TIGR02168  550 VVVENLNAAKKAI----------AFLKQNELGRVTfLPLDSIKGT-EIQGNDREILKNIEGFLGVAKDLVKFDPKLRKal 618

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2353 ---FSYEQLETDLQASRELTSRLHEEINM--KEQKIIS---LLSGKEEAIQVAIAELRQqhdkEIKELENLLSQEEEENI 2424
Cdd:TIGR02168  619 sylLGGVLVVDDLDNALELAKKLRPGYRIvtLDGDLVRpggVITGGSAKTNSSILERRR----EIEELEEKIEELEEKIA 694

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2425 VLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERhlsiilekdqlIQEAAAEN 2504
Cdd:TIGR02168  695 ELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKE-----------LTELEAEI 763

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2505 NKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDSQQKQLlevqlqqnKELENKYAKLEEKLKESEEANED 2584
Cdd:TIGR02168  764 EELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAEL--------TLLNEEAANLRERLESLERRIAA 835

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2585 LRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTALQEEgtlglyhaqLKVKEEEVHRLSALFSSSQKRIAELEEELvcv 2664
Cdd:TIGR02168  836 TERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESE---------LEALLNERASLEEALALLRSELEELSEEL--- 903

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2665 qKEAAKKVGEIEDK---LKKELKHLHHDAGIMRNETETAEERVAELARDLVEM-EQKLLMVTKENKGLTAQIQSFGRSMS 2740
Cdd:TIGR02168  904 -RELESKRSELRREleeLREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEaEALENKIEDDEEEARRRLKRLENKIK 982

                          890       900       910
                   ....*....|....*....|....*....|..
gi 1034632655 2741 SLQNSRDHANEELDELKRKYDASLKELAQLKE 2772
Cdd:TIGR02168  983 ELGPVNLAAIEEYEELKERYDFLTAQKEDLTE 1014
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1352-2179 2.87e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 92.81  E-value: 2.87e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1352 IESLKTVSHEAEVHAEsLQQKLESSQLQIAGLEhLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQ 1431
Cdd:TIGR02168  202 LKSLERQAEKAERYKE-LKAELRELELALLVLR-LEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSEL 279

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1432 EDLIKALHTQLEMQAKEH---DERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEALKEnksLQEELSLA 1508
Cdd:TIGR02168  280 EEEIEELQKELYALANEIsrlEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEE---LKEELESL 356

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1509 RGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMdrsllenQSLSSSCESLKLALEGLTEDKEKLVKE 1588
Cdd:TIGR02168  357 EAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEI-------ERLEARLERLEDRRERLQQEIEELLKK 429

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1589 IESLKSSKIAESTEwqekhkELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEaeq 1668
Cdd:TIGR02168  430 LEEAELKELQAELE------ELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQEN--- 500

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1669 emeemkekmrkfAKSKQQKILELEEENDRLRAEVHPAGDtakecmetLLSSNASMKEELERVkmeyetLSKKFQSLMSEk 1748
Cdd:TIGR02168  501 ------------LEGFSEGVKALLKNQSGLSGILGVLSE--------LISVDEGYEAAIEAA------LGGRLQAVVVE- 553

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1749 dSLSEEVQDLKHQIEGNVSKQANLEATEKHDNQtnvteegtqsIPGETEEQDSLSMSTRPTCSESVPSAKSANPAVSkDF 1828
Cdd:TIGR02168  554 -NLNAAKKAIAFLKQNELGRVTFLPLDSIKGTE----------IQGNDREILKNIEGFLGVAKDLVKFDPKLRKALS-YL 621

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1829 SSH----DEINNYLQQIDQLK--ERIAGLEEEkQKNKEFSQTLENEKNTllSQISTKDGELKMLQEEVTKMNLLNQQIQE 1902
Cdd:TIGR02168  622 LGGvlvvDDLDNALELAKKLRpgYRIVTLDGD-LVRPGGVITGGSAKTN--SSILERRREIEELEEKIEELEEKIAELEK 698

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1903 ELSRVTKLKETAEEEKDDLEERlmnqLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVE 1982
Cdd:TIGR02168  699 ALAELRKELEELEEELEQLRKE----LEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAE 774

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1983 SEIrKEYLEKIQGAQKEPGN-KSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEfvqtesqKDLEITKEN 2061
Cdd:TIGR02168  775 EEL-AEAEAEIEELEAQIEQlKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATE-------RRLEDLEEQ 846

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2062 LAQAVEHRKKAQAELASFKVLLDDTQSEaarvLADNLKLKKELQSNKESVKSQMKQKDEDLerrleqaeekhlkekKNMQ 2141
Cdd:TIGR02168  847 IEELSEDIESLAAEIEELEELIEELESE----LEALLNERASLEEALALLRSELEELSEEL---------------RELE 907

                          810       820       830
                   ....*....|....*....|....*....|....*...
gi 1034632655 2142 EKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQENL 2179
Cdd:TIGR02168  908 SKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERL 945
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 758-1532 7.58e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 91.66  E-value: 7.58e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  758 VTELRAQVKQLEMNLAEAERQRRLdyesqtaHDNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQS 837
Cdd:TIGR02168  195 LNELERQLKSLERQAEKAERYKEL-------KAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEE 267

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  838 QLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISfsmtEKMVQLN 917
Cdd:TIGR02168  268 KLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELA----EELAELE 343

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  918 EEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEmspagqiskeeLQHEFDLLKKENEQRKRKLQAA 997
Cdd:TIGR02168  344 EKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQ-----------LELQIASLNNEIERLEARLERL 412

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  998 LINRKELLQRVSRLEEELANL-KDESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIYLKQTiSEKEVELQHIR 1076
Cdd:TIGR02168  413 EDRRERLQQEIEELLKKLEEAeLKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAA-ERELAQLQARL 491

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1077 KDLEEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEISENQ-----------AIIQKLITSNTDASDGDSVALVKE--- 1142
Cdd:TIGR02168  492 DSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEgyeaaieaalgGRLQAVVVENLNAAKKAIAFLKQNelg 571

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1143 TVVISPPCTGSSEHWKPELEEKI----------LALEKEKEQLQKKLQ---------EALTSRKAILKKAQEKER----- 1198
Cdd:TIGR02168  572 RVTFLPLDSIKGTEIQGNDREILkniegflgvaKDLVKFDPKLRKALSyllggvlvvDDLDNALELAKKLRPGYRivtld 651

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1199 -----------------------------HLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVRESidgklpS 1249
Cdd:TIGR02168  652 gdlvrpggvitggsaktnssilerrreieELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEEL------S 725

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1250 TDQQESCSSTPGLEEPLFKATEQHHTQPVLESNLcpdwpshseDASALQGGTSVAQIKAQLKEIEAEKVELELKV----- 1324
Cdd:TIGR02168  726 RQISALRKDLARLEAEVEQLEERIAQLSKELTEL---------EAEIEELEERLEEAEEELAEAEAEIEELEAQIeqlke 796

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1325 --SSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLEH--------LRELQPKLD 1394
Cdd:TIGR02168  797 elKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAeieeleelIEELESELE 876

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1395 ELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEmQAKEHDERIKQ------------LQVELCE 1462
Cdd:TIGR02168  877 ALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLA-QLELRLEGLEVridnlqerlseeYSLTLEE 955

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1034632655 1463 MKQKPEEIGEESRAKQQIQRKLQAALIS----RKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKE 1532
Cdd:TIGR02168  956 AEALENKIEDDEEEARRRLKRLENKIKElgpvNLAAIEEYEELKERYDFLTAQKEDLTEAKETLEEAIEEIDRE 1029
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 190-1018 3.62e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 82.80  E-value: 3.62e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  190 QQLQEKEEFISTLQAQLSQTQAEQAaqvvREKDARFETQVRLHEDELLQLVTQADVETEMQQKLRVLQRKLEEHEESLVG 269
Cdd:TIGR02168  213 ERYKELKAELRELELALLVLRLEEL----REELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQK 288

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  270 RaqvVDLLQQELTAAEQRNQILSQQLQQMEAEhntlRNTVETEREESKILLEKMELEVAERKLSFHNLQEEMHHLLEQFE 349
Cdd:TIGR02168  289 E---LYALANEISRLEQQKQILRERLANLERQ----LEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELE 361

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  350 QAGQAQAELESRYSALEQKHkaemeektshilslqktgQELQSACDALKDQNSKLlqdkNEQAVQSAQTIQQLEDQLQQK 429
Cdd:TIGR02168  362 ELEAELEELESRLEELEEQL------------------ETLRSKVAQLELQIASL----NNEIERLEARLERLEDRRERL 419

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  430 SKEISQFLNRLPLQQHETASQTSfpdvynEGTQAVTEENIASLQKRVVELENEKGALLLSSIELEELKAENEKLSSQITL 509
Cdd:TIGR02168  420 QQEIEELLKKLEEAELKELQAEL------EELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDS 493

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  510 LEA-QNRTGEADREVSEI---------------SIVDIANKRSSSAE----ESGQDVLENTFSQKHKELSVLLlemKEAQ 569
Cdd:TIGR02168  494 LERlQENLEGFSEGVKALlknqsglsgilgvlsELISVDEGYEAAIEaalgGRLQAVVVENLNAAKKAIAFLK---QNEL 570

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  570 EEIAFLKLQLQGKRAEEADHEVLdQKEMKQMEGEGIAPIKMKVFLEDTGQDFplmpneESSLPAVEKEQASTEHQSRTSE 649
Cdd:TIGR02168  571 GRVTFLPLDSIKGTEIQGNDREI-LKNIEGFLGVAKDLVKFDPKLRKALSYL------LGGVLVVDDLDNALELAKKLRP 643

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  650 EISLNDAGVELKS-----TKQDGDKSLSAvpdigQCHQDELERLKSQILELELNFHKAqeiyEKNLDEKAKEISNLNQLI 724
Cdd:TIGR02168  644 GYRIVTLDGDLVRpggviTGGSAKTNSSI-----LERRREIEELEEKIEELEEKIAEL----EKALAELRKELEELEEEL 714

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  725 EEFKKNADNNSSAFTALSEERDQLLSQVKELSmvtelrAQVKQLEMNLAEAERQRrldyesqtahdNLLTEQIHSLSIEA 804
Cdd:TIGR02168  715 EQLRKELEELSRQISALRKDLARLEAEVEQLE------ERIAQLSKELTELEAEI-----------EELEERLEEAEEEL 777

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  805 KSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEK 884
Cdd:TIGR02168  778 AEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESL 857

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  885 KRDVETLQQTIEEKDQQVTEISF---SMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQN 961
Cdd:TIGR02168  858 AAEIEELEELIEELESELEALLNeraSLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVR 937

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1034632655  962 YDEMspAGQISkEELQHEFDLLKKENEQRKRKLQaalinrkELLQRVSRLEEELANL 1018
Cdd:TIGR02168  938 IDNL--QERLS-EEYSLTLEEAEALENKIEDDEE-------EARRRLKRLENKIKEL 984
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1833-2378 1.49e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 77.28  E-value: 1.49e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1833 EINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVtkmNLLNQQIQEELSRVTKLKE 1912
Cdd:COG1196    233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEE---YELLAELARLEQDIARLEE 309

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1913 TAEEEKDDLEeRLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEK 1992
Cdd:COG1196    310 RRRELEERLE-ELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEEL 388

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1993 IQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKA 2072
Cdd:COG1196    389 LEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAEL 468

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2073 QAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKN----MQEKLDALR 2148
Cdd:COG1196    469 LEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAyeaaLEAALAAAL 548

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2149 REKVHLEETIGEIQVTLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEEIRLK 2228
Cdd:COG1196    549 QNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLV 628

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2229 EDNC-------SVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHS 2301
Cdd:COG1196    629 AARLeaalrraVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERE 708

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1034632655 2302 SQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLhEEINM 2378
Cdd:COG1196    709 LAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEAL-GPVNL 784
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1369-1936 2.40e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 76.51  E-value: 2.40e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1369 LQQKLESSQLQIAGLeHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKE 1448
Cdd:COG1196    218 LKEELKELEAELLLL-KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAE 296

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1449 HDERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSA 1528
Cdd:COG1196    297 LARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAE 376

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1529 QNKEKDTVLGRLALLQEERDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAEstewQEKHK 1608
Cdd:COG1196    377 AEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEA----AEEEA 452

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1609 ELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETE------KQLQEAEQEMEEMKEKMRKFAK 1682
Cdd:COG1196    453 ELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEgflegvKAALLLAGLRGLAGAVAVLIGV 532

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1683 SKQQKILELEEENDRLRAEVHPAGDTAKECMETLLSSNASMKEELERVKMEYETLSKKFQSLM----------SEKDSLS 1752
Cdd:COG1196    533 EAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGaigaavdlvaSDLREAD 612

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1753 EEVQDLKHQIEGNVSKQANLEATEKHDNQTN-----VTEEGTQSIPGETEEQDSLSMSTRPTCSESVPSAKSANPAVSKD 1827
Cdd:COG1196    613 ARYYVLGDTLLGRTLVAARLEAALRRAVTLAgrlreVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEE 692

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1828 FSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRV 1907
Cdd:COG1196    693 LELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERL 772

                          570       580       590
                   ....*....|....*....|....*....|....*....
gi 1034632655 1908 TKLKE-------TAEEEKDDLEER---LMNQLAELNGSI 1936
Cdd:COG1196    773 EREIEalgpvnlLAIEEYEELEERydfLSEQREDLEEAR 811
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2453-3186 2.41e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 73.55  E-value: 2.41e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2453 QQKAQLDSFVKSMSSLQNDRDRIVGDYQQLE---ERHLSIILEKDQLIQEA-------AAENNKLKEEIRGLRSHMDDLN 2522
Cdd:TIGR02168  236 ELREELEELQEELKEAEEELEELTAELQELEeklEELRLEVSELEEEIEELqkelyalANEISRLEQQKQILRERLANLE 315

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2523 SENAKLDAELIQYREDLNQVITIKDSQQKQLLEVQ------LQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEK 2596
Cdd:TIGR02168  316 RQLEELEAQLEELESKLDELAEELAELEEKLEELKeeleslEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQI 395

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2597 QDLSKEIESLKVSISQLTRQVTALQEE-----------------GTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEE 2659
Cdd:TIGR02168  396 ASLNNEIERLEARLERLEDRRERLQQEieellkkleeaelkelqAELEELEEELEELQEELERLEEALEELREELEEAEQ 475

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2660 ELVCVQKEAAKKVGEIED----------------KLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTK 2723
Cdd:TIGR02168  476 ALDAAERELAQLQARLDSlerlqenlegfsegvkALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQAVVVENL 555

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2724 ENKGLTAQIQ---SFGRSMSSLQNSRDHA-----NEELDELKRKYDASLKELAQLKEQglLNRERDALLSETAFSMNSTE 2795
Cdd:TIGR02168  556 NAAKKAIAFLkqnELGRVTFLPLDSIKGTeiqgnDREILKNIEGFLGVAKDLVKFDPK--LRKALSYLLGGVLVVDDLDN 633

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2796 ENSLSHLEKLNQQLLSKDEQLLHLSSQLedsYNQVQSFSKAMASLQNERDHLWNELEKFRkseegkqrsaaqpstspAEV 2875
Cdd:TIGR02168  634 ALELAKKLRPGYRIVTLDGDLVRPGGVI---TGGSAKTNSSILERRREIEELEEKIEELE-----------------EKI 693

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2876 QSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELHPLKAQLQEYQDKTkAFQIMQEELRQENLSWQHELHQLRMEK 2955
Cdd:TIGR02168  694 AELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQL-EERIAQLSKELTELEAEIEELEERLEE 772

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2956 SSWEIHERRMKEQYLMAisDKDQQLSHLQNLIRELRSSSSQTQPLKVQYQRQASpetsaspdGSQNLVYETELLRTQLND 3035
Cdd:TIGR02168  773 AEEELAEAEAEIEELEA--QIEQLKEELKALREALDELRAELTLLNEEAANLRE--------RLESLERRIAATERRLED 842

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 3036 SLKEIHQKELRIQQLNSNFSQLLEEKNTLSIQLCDTSQSLRENQQHYGDLLNHcavLEKQVQELQAVSKEKGPLNIDvap 3115
Cdd:TIGR02168  843 LEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSE---LEELSEELRELESKRSELRRE--- 916

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1034632655 3116 gapqekngvhRKSDPEELREPQQSFSEAQQQLCNTRQEVNELRKLLEEERDQRVAA-ENALSVAEEQIRRLE 3186
Cdd:TIGR02168  917 ----------LEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKiEDDEEEARRRLKRLE 978
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 758-1119 3.63e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 69.58  E-value: 3.63e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  758 VTELRAQVKQLEmnlAEAERQRRldYesqtahdnllteqihsLSIEAKSKDVKIEVLQNELDDVQLQfseqstlIRSLQS 837
Cdd:COG1196    195 LGELERQLEPLE---RQAEKAER--Y----------------RELKEELKELEAELLLLKLRELEAE-------LEELEA 246

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  838 QLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLN 917
Cdd:COG1196    247 ELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELA 326

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  918 EEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEMSPAGQISKEELQHEFDLLKKENEQRKRkLQAA 997
Cdd:COG1196    327 ELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQ-LEEL 405

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  998 LINRKELLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKENKEysekcvtskcqeieiylkqtisEKEVELQHIRK 1077
Cdd:COG1196    406 EEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEA----------------------ELEEEEEALLE 463

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|..
gi 1034632655 1078 DLEEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEISENQA 1119
Cdd:COG1196    464 LLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEG 505
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1494-2087 1.33e-10

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 67.40  E-value: 1.33e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1494 ALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMD---RSLLENQSLSSSCES 1570
Cdd:PRK03918   163 AYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEkleKEVKELEELKEEIEE 242

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1571 LKLALEGLTEDKEKL---VKEIESLKSSKIAESTEWQEKHKELQ------KEYEILLQSYENVSNEAERIQHVVEAVRQE 1641
Cdd:PRK03918   243 LEKELESLEGSKRKLeekIRELEERIEELKKEIEELEEKVKELKelkekaEEYIKLSEFYEEYLDELREIEKRLSRLEEE 322

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1642 KQELYGKLRstEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHPagdtakecmetllssna 1721
Cdd:PRK03918   323 INGIEERIK--ELEEKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTG----------------- 383

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1722 smkEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEgnvSKQANLEATEKHDNQTNV-----TEEGTQSIPGET 1796
Cdd:PRK03918   384 ---LTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIK---ELKKAIEELKKAKGKCPVcgrelTEEHRKELLEEY 457

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1797 EEQDSLSMSTRPTCSESVPSAKSANPAVSKDFSSHDEINNYLQQIDQLKEriagLEEE-KQKNKEFSQTLENEKNTLLSQ 1875
Cdd:PRK03918   458 TAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQLKE----LEEKlKKYNLEELEKKAEEYEKLKEK 533

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1876 ISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAEEEKDDLEERLMNQLAELNGSIGNYcqdvtdaqiknELLES 1955
Cdd:PRK03918   534 LIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKEL-----------EPFYN 602

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1956 EMKNLKKCVSELEEEKQQLVKEKTKVESEIrkEYLEKIQGAQKEPgnkshAKELQELLKE-KQQEVKQLQKDCIRYQEKI 2034
Cdd:PRK03918   603 EYLELKDAEKELEREEKELKKLEEELDKAF--EELAETEKRLEEL-----RKELEELEKKySEEEYEELREEYLELSREL 675

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1034632655 2035 SALERTVKALEFVQTESQKDLEITKENLaqavEHRKKAQAELASFKVLLDDTQ 2087
Cdd:PRK03918   676 AGLRAELEELEKRREEIKKTLEKLKEEL----EEREKAKKELEKLEKALERVE 724
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 634-1229 4.77e-10

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 65.91  E-value: 4.77e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  634 VEKEQASTEHQSRTSEEISLNDAGVELKSTKQDGDKSLSAVPDIGQCHQDELERLKSQILELELNFHKAQEIYEKNLDEK 713
Cdd:pfam15921  243 VEDQLEALKSESQNKIELLLQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQARNQNSMYMRQLSDL 322

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  714 AKEISNLNQLIEEFKKNADNNssaftaLSEERDQLLSQVKELSMVTELRAQVKQLEMNLAEAERQRRLDYESQTAHDNLL 793
Cdd:pfam15921  323 ESTVSQLRSELREAKRMYEDK------IEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELSLE 396

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  794 TEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVL-------EGAERVRHISSKVEELSQA 866
Cdd:pfam15921  397 KEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMaaiqgknESLEKVSSLTAQLESTKEM 476

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  867 LSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTeKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKE 946
Cdd:pfam15921  477 LRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEIT-KLRSRVDLKLQELQHLKNEGDHLRNVQTECEALKL 555

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  947 QVEEDNEVSSGLKQNYDEMSP----------AGQISKEELQ----------HEFDLLKKENEQRKRKLQAAL----INRK 1002
Cdd:pfam15921  556 QMAEKDKVIEILRQQIENMTQlvgqhgrtagAMQVEKAQLEkeindrrlelQEFKILKDKKDAKIRELEARVsdleLEKV 635

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1003 ELLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIY---LKQTISEKEVELQHIRKDL 1079
Cdd:pfam15921  636 KLVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTtnkLKMQLKSAQSELEQTRNTL 715

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1080 EEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEisenqaiIQKLITSNTDASDGDSVALVKETVVISPPCTGSSEHWKP 1159
Cdd:pfam15921  716 KSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSK-------IQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKM 788

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1160 ELEEKILALEkekeqlQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIG 1229
Cdd:pfam15921  789 AGELEVLRSQ------ERRLKEKVANMEVALDKASLQFAECQDIIQRQEQESVRLKLQHTLDVKELQGPG 852
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 201-755 7.86e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 64.96  E-value: 7.86e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  201 TLQAQLSQTQAEQAA---QVVREKDARFETQVRLHEDELLQLVTQADVE----TEMQQKLRVLQRKLEEHEESLVGRAQV 273
Cdd:COG1196    217 ELKEELKELEAELLLlklRELEAELEELEAELEELEAELEELEAELAELeaelEELRLELEELELELEEAQAEEYELLAE 296

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  274 VDLLQQELTAAEQRNQILSQQLQQMEAEHNTLRNTVETEREESKILLEKMELEVAERKLSFHNLQEEMHHLLEQFEQAGQ 353
Cdd:COG1196    297 LARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAE 376

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  354 AQAELESRYSALEQKhKAEMEEKTSHILSLQKTGQELQSACDALKDQNSKLLQDKNEQAVQSAQTIQQLEDQLQQKSKEI 433
Cdd:COG1196    377 AEEELEELAEELLEA-LRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELE 455

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  434 SQFLNrlpLQQHETASQTSFPDVYNEGTQAVTEENIASLQKRVVELENEKGALLLSSIELEELKAENEKLSSQI-TLLEA 512
Cdd:COG1196    456 EEEEA---LLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVaVLIGV 532

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  513 QNRTGEADREVSEISIVDIANKRSSSAEESGQDVLEN-----TFSQKHK-------ELSVLLLEMKEAQEEIAFLKLQLQ 580
Cdd:COG1196    533 EAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAkagraTFLPLDKiraraalAAALARGAIGAAVDLVASDLREAD 612

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  581 GKRAEEADHEVLDQKEMKQMEGEGIAPIKMKVFLEDTGQDFPLMPNEESSLPAVEKEQASTEHQSRTSEEISLNDAGVEL 660
Cdd:COG1196    613 ARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEE 692

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  661 KSTKQDgdkslsavpdigqchQDELERLKSQILELELNFHKAQEIYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTA 740
Cdd:COG1196    693 LELEEA---------------LLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELP 757

                          570
                   ....*....|....*
gi 1034632655  741 LSEERDQLLSQVKEL 755
Cdd:COG1196    758 EPPDLEELERELERL 772
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1838-2338 9.98e-10

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 64.70  E-value: 9.98e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1838 LQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMNLLnQQIQEELSRVTKLKETAEEE 1917
Cdd:PRK03918   230 VKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKEL-KEKAEEYIKLSEFYEEYLDE 308

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1918 KDDLEERLMNQLAELNGsIGNYCQDVTDAQIKNELLESEMKNLKKCVSELE------EEKQQLVKEKTKVESEIRKEYLE 1991
Cdd:PRK03918   309 LREIEKRLSRLEEEING-IEERIKELEEKEERLEELKKKLKELEKRLEELEerhelyEEAKAKKEELERLKKRLTGLTPE 387

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1992 KIQGAQKEPGNKShaKELQELLKEKQQEVKQLQKDCIRYQEKISALER------------TVKALEFVQTESQKDLEITK 2059
Cdd:PRK03918   388 KLEKELEELEKAK--EEIEEEISKITARIGELKKEIKELKKAIEELKKakgkcpvcgrelTEEHRKELLEEYTAELKRIE 465

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2060 ENLAQAVEHRKKAQAELASFKVLLddtqsEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKN 2139
Cdd:PRK03918   466 KELKEIEEKERKLRKELRELEKVL-----KKESELIKLKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGE 540

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2140 MQ------EKLDALRREKVHLEETIGEIQVTLNKKDKEVQQL----QENLDSTVTQLAAFTKSMSSLQDDRDRVIDEAKK 2209
Cdd:PRK03918   541 IKslkkelEKLEELKKKLAELEKKLDELEEELAELLKELEELgfesVEELEERLKELEPFYNEYLELKDAEKELEREEKE 620

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2210 werkfsdaIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELKINISRLEHdkqiweskaqtevqlqqkvcdtlqgenkell 2289
Cdd:PRK03918   621 --------LKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEY------------------------------- 661

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....*....
gi 1034632655 2290 sqlEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLE 2338
Cdd:PRK03918   662 ---EELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEERE 707
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1300-2178 5.11e-08

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 59.21  E-value: 5.11e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1300 GTSVAQIKAQLKEIEAEKVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQ 1379
Cdd:pfam02463  161 EAAGSRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERID 240

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1380 IagLEHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVE 1459
Cdd:pfam02463  241 L--LQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKE 318

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1460 LCEMKQKpeeigeesrakqqIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGR 1539
Cdd:pfam02463  319 SEKEKKK-------------AEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESER 385

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1540 LALLQEERDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQ 1619
Cdd:pfam02463  386 LSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDEL 465

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1620 SYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLR 1699
Cdd:pfam02463  466 ELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAI 545

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1700 AEVHPAGDTAKECMETLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQANLEATEKHD 1779
Cdd:pfam02463  546 STAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVV 625

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1780 NQTNVTEEGTQSIPGETEEQDSLSMstrptcsesVPSAKSANPAVSKDFSSHDEINNYLQQIDQLKERIAGLEEEKQKNK 1859
Cdd:pfam02463  626 EGILKDTELTKLKESAKAKESGLRK---------GVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILR 696

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1860 EFSQTLENEKNTLLSQISTKDGELKMLQEEVT-KMNLLNQQIQEELSRVTKLKETAEEEKDDLEERLMNQLAELNGSIGN 1938
Cdd:pfam02463  697 RQLEIKKKEQREKEELKKLKLEAEELLADRVQeAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKEL 776

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1939 YCQDVTDAQIKNElLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQgaqkepgnKSHAKELQELLKEKQQ 2018
Cdd:pfam02463  777 AEEREKTEKLKVE-EEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIK--------EEELEELALELKEEQK 847

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2019 EVKQLQKDCIRYQEKISALERTVKALEfvqtESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNL 2098
Cdd:pfam02463  848 LEKLAEEELERLEEEITKEELLQELLL----KEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERI 923

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2099 KLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQEN 2178
Cdd:pfam02463  924 KEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEE 1003
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2637-2940 9.52e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 58.41  E-value: 9.52e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2637 EEEVHRLSALFSSSQKRIAELEEelvcvQKEAAKKVGEIEDKLKK--------ELKHLHHDAGIMRNETETAEERVAELA 2708
Cdd:COG1196    185 EENLERLEDILGELERQLEPLER-----QAEKAERYRELKEELKEleaellllKLRELEAELEELEAELEELEAELEELE 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2709 RDLVEME-------QKLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKEQGLLNRERD 2781
Cdd:COG1196    260 AELAELEaeleelrLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEEL 339

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2782 ALLSETAFSMNSTEENSLSHLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKFR----KS 2857
Cdd:COG1196    340 EELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLerleRL 419

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2858 EEGKQRSAAQPSTSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELHPLKAQLQEYQDKTKAFQIMQEEL 2937
Cdd:COG1196    420 EEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEA 499


                   ...
gi 1034632655 2938 RQE 2940
Cdd:COG1196    500 EAD 502
PTZ00121 PTZ00121
MAEBL; Provisional
 701-1228 2.68e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 57.07  E-value: 2.68e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  701 KAQEIYEKNLDEKAKEISNLNQLIE--EFKKNADNNSSAFTALSEERDQLLSQVKELSMVTELRAQVKQLEMNLAEAERQ 778
Cdd:PTZ00121  1285 KAEEKKKADEAKKAEEKKKADEAKKkaEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEE 1364

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  779 RRLDYESQTAHDNLLTEQIHSLSIEAKSKD---VKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVL----EGAE 851
Cdd:PTZ00121  1365 KAEAAEKKKEEAKKKADAAKKKAEEKKKADeakKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAkkkaEEAK 1444

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  852 RVRHISSKVEELSQA--LSQKELEITKMDQLL--LEKKRDVETLQQTIEEKDQQVTEISFSMTEKMvqlNEEKFSLGVEI 927
Cdd:PTZ00121  1445 KADEAKKKAEEAKKAeeAKKKAEEAKKADEAKkkAEEAKKADEAKKKAEEAKKKADEAKKAAEAKK---KADEAKKAEEA 1521

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  928 KTLKEqlnlLSRAEEAKKEQVEEDNEVssglKQNYDEMSPAGQISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQR 1007
Cdd:PTZ00121  1522 KKADE----AKKAEEAKKADEAKKAEE----KKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEAR 1593

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1008 VSRLEEELANLKDESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIYLKQTISEKEVELQHIRKDLEEKLAAEE 1087
Cdd:PTZ00121  1594 IEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEED 1673

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1088 QFQAlvKQMNQTLQDKTNQIDLLQAEISENQaiiqklitsntdasdgdsvalvketvvisppctgssehwKPELEEKILA 1167
Cdd:PTZ00121  1674 KKKA--EEAKKAEEDEKKAAEALKKEAEEAK---------------------------------------KAEELKKKEA 1712

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1034632655 1168 LEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENI 1228
Cdd:PTZ00121  1713 EEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEI 1773
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1946-2687 8.60e-07

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 54.98  E-value: 8.60e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1946 AQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQK 2025
Cdd:pfam02463  179 IEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQ 258

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2026 DciryQEKISALERTVKALEFVQTESQKdleITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQ 2105
Cdd:pfam02463  259 E----IEKEEEKLAQVLKENKEEEKEKK---LQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELK 331

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2106 SNKESVKSQMKQKDEdlerrLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQEnldstvtq 2185
Cdd:pfam02463  332 KEKEEIEELEKELKE-----LEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELE-------- 398

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2186 LAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELKINISRLEHDKQIWES 2265
Cdd:pfam02463  399 LKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQ 478

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2266 KAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQE 2345
Cdd:pfam02463  479 LVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATAD 558

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2346 ADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKIISLLSGKEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIV 2425
Cdd:pfam02463  559 EVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLK 638

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2426 LEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRivgdyQQLEERHLSIILEKDQLIQEAAAENN 2505
Cdd:pfam02463  639 ESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAES-----ELAKEEILRRQLEIKKKEQREKEELK 713

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2506 KLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDSQQKQLLEVQLQQNKELENKYAKLEEKLKESEEANEDL 2585
Cdd:pfam02463  714 KLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKE 793

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2586 RRSFNALQEEKQDLSKEIESLKVSISQLTRQVTALQEEGTLGLYHAQLKVKEEEvhrLSALFSSSQKRIAELEEELVCVQ 2665
Cdd:pfam02463  794 EKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQK---LEKLAEEELERLEEEITKEELLQ 870

                          730       740
                   ....*....|....*....|..
gi 1034632655 2666 KEAAKKVGEIEDKLKKELKHLH 2687
Cdd:pfam02463  871 ELLLKEEELEEQKLKDELESKE 892
PRK11281 PRK11281
mechanosensitive channel MscK;
151-507 3.41e-06

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 52.99  E-value: 3.41e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  151 HKLQEKEEliSTLQAQLTQAQA--EQPAQSSTEMEEfvmMKQQLQEKEEFISTLQAQLSQTQAeQAAQVVREkdaRFETq 228
Cdd:PRK11281    51 QKLLEAED--KLVQQDLEQTLAllDKIDRQKEETEQ---LKQQLAQAPAKLRQAQAELEALKD-DNDEETRE---TLST- 120

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  229 vrLHEDELLQLVTQadVETEMQQklrvLQRKLEEHEESLVGRAQVVDLLQQELTAAEQRNQILSQQLQQMEAEHNTLRNT 308
Cdd:PRK11281   121 --LSLRQLESRLAQ--TLDQLQN----AQNDLAEYNSQLVSLQTQPERAQAALYANSQRLQQIRNLLKGGKVGGKALRPS 192

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  309 VETERE------ESKILLEKMELEVAERKLSFHNLQeemHHLLEqfEQAGQAQAELESRYSALEQKHKAEMEektshils 382
Cdd:PRK11281   193 QRVLLQaeqallNAQNDLQRKSLEGNTQLQDLLQKQ---RDYLT--ARIQRLEHQLQLLQEAINSKRLTLSE-------- 259

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  383 lqKTGQELQSACDALKDQNSKLLQDKNEQAVQSAQT-IQQLE--DQLQQKSKEISQFLNRlpLQQhetasqtsfpdvyne 459
Cdd:PRK11281   260 --KTVQEAQSQDEAARIQANPLVAQELEINLQLSQRlLKATEklNTLTQQNLRVKNWLDR--LTQ--------------- 320

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1034632655  460 gTQAVTEENIASLQkrvvelenekGALLLSSIELEELKA-----ENEKLSSQI 507
Cdd:PRK11281   321 -SERNIKEQISVLK----------GSLLLSRILYQQQQAlpsadLIEGLADRI 362
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 1823-2061 5.66e-05

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 49.45  E-value: 5.66e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1823 AVSKDFSSHDEINNYLQQIDQLKERIAgleeEKQKNKEFSQTLENEKNTLLSQISTKDGELkmlqeEVTKMNLLNQQIQE 1902
Cdd:NF012221  1536 ATSESSQQADAVSKHAKQDDAAQNALA----DKERAEADRQRLEQEKQQQLAAISGSQSQL-----ESTDQNALETNGQA 1606

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1903 ELSRVTKLKETAEEEKDDLEERL--MNQLAELNGSIGN-YCQDVTDAQIKNelLESEMKNLKKCVSE-LEEEKQQLVKEK 1978
Cdd:NF012221  1607 QRDAILEESRAVTKELTTLAQGLdaLDSQATYAGESGDqWRNPFAGGLLDR--VQEQLDDAKKISGKqLADAKQRHVDNQ 1684

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1979 TKVESEIRKEYLEKIQGAQKEPG-------NKSHAKELQELLKEKQQEVKQLQKDC-IRYQEKISALERTVKALEFVQTE 2050
Cdd:NF012221  1685 QKVKDAVAKSEAGVAQGEQNQANaeqdiddAKADAEKRKDDALAKQNEAQQAESDAnAAANDAQSRGEQDASAAENKANQ 1764

                          250
                   ....*....|.
gi 1034632655 2051 SQKDLEITKEN 2061
Cdd:NF012221  1765 AQADAKGAKQD 1775
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 35-615 9.87e-05

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 48.19  E-value: 9.87e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655   35 HQESDMEFNNTTQEDVQERLAYAEQLVVELKDIIRQKDVQLQQKDEALQEERKAADNKIKKLKLHAKAKLTSLNKYIEEM 114
Cdd:pfam15921   75 HIERVLEEYSHQVKDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTVHEL 154

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  115 KAQG--------------------------------GTVLPTEPQSEEQLSKHDKSSTEEEMEIEKIKHK-LQEKEELIS 161
Cdd:pfam15921  155 EAAKclkedmledsntqieqlrkmmlshegvlqeirSILVDFEEASGKKIYEHDSMSTMHFRSLGSAISKiLRELDTEIS 234

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  162 TLQAQLTQAQAEQPAQSSTEMEEFVMMKQQLQEK-EEFISTLQAQL-----------SQTQAEQAAQVVREKDARFETQV 229
Cdd:pfam15921  235 YLKGRIFPVEDQLEALKSESQNKIELLLQQHQDRiEQLISEHEVEItgltekassarSQANSIQSQLEIIQEQARNQNSM 314

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  230 RL-HEDELLQLVTQadVETEMQQKLRVLQRKLEEHEESLVGRAQVVDLLQQELTAAEQRNQILSQQLQQMEAEHNTLRNT 308
Cdd:pfam15921  315 YMrQLSDLESTVSQ--LRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKE 392

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  309 VETEREESKILLEK-----MELEVAERKLSFHNLQ-EEMHHLLEQFEQagQAQAELESRYSALEQKHKAeMEEKTSHILS 382
Cdd:pfam15921  393 LSLEKEQNKRLWDRdtgnsITIDHLRRELDDRNMEvQRLEALLKAMKS--ECQGQMERQMAAIQGKNES-LEKVSSLTAQ 469

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  383 LQKTGQELQSACDALKDQnsKLLQDKNEQAVQS-AQTIQQLEDQLQQKSKEISQFLNRLPLQ----QHETASQTSFPDVY 457
Cdd:pfam15921  470 LESTKEMLRKVVEELTAK--KMTLESSERTVSDlTASLQEKERAIEATNAEITKLRSRVDLKlqelQHLKNEGDHLRNVQ 547

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  458 NE---------GTQAVTE---ENIASLQKRVVELENEKGALLLSS-----------IELEELKAENEKLSSQITLLEAQn 514
Cdd:pfam15921  548 TEcealklqmaEKDKVIEilrQQIENMTQLVGQHGRTAGAMQVEKaqlekeindrrLELQEFKILKDKKDAKIRELEAR- 626

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  515 rtgEADREVSEISIVDIANKRSSSAEESGQ--DVLENTFSQKHKELSVLLLEM---------KEAQEEIAFLKLQLQGKR 583
Cdd:pfam15921  627 ---VSDLELEKVKLVNAGSERLRAVKDIKQerDQLLNEVKTSRNELNSLSEDYevlkrnfrnKSEEMETTTNKLKMQLKS 703

                          650       660       670
                   ....*....|....*....|....*....|..
gi 1034632655  584 AEEADHEVldQKEMKQMEGEGIAPIKMKVFLE 615
Cdd:pfam15921  704 AQSELEQT--RNTLKSMEGSDGHAMKVAMGMQ 733
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 46-301 9.82e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 44.93  E-value: 9.82e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655   46 TQEDVQERLAYAEQLVVELKDIIRQKDVQLQQKDEALQEERKAADNKIKKLKLHAKAKLTSLNKYIEEMKAQGGTVLPTE 125
Cdd:COG1196    271 ELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAE 350

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  126 PQSEEQLSKHDKSSTEEEMEIEKIKHKLQEKEELISTLQAQLTQAQAEQPAQsstemeefvmmkQQLQEKEEFISTLQAQ 205
Cdd:COG1196    351 EELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQL------------EELEEAEEALLERLER 418

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  206 LSQTQAEQAAQVVREKDARfetqvrlhEDELLQLVTQADVETEMQQKLRVLQRKLEEHEESLVGRAQVVDLLQQELTAAE 285
Cdd:COG1196    419 LEEELEELEEALAELEEEE--------EEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAA 490

                          250
                   ....*....|....*.
gi 1034632655  286 QRNQILSQQLQQMEAE 301
Cdd:COG1196    491 ARLLLLLEAEADYEGF 506
alph_xenorhab_A NF033928
alpha-xenorhabdolysin family binary toxin subunit A; Alpha-xenorhabdolysin was the founding ...
 2036-2205 7.05e-03

alpha-xenorhabdolysin family binary toxin subunit A; Alpha-xenorhabdolysin was the founding member of a family of alpha-helical pore-forming binary toxins. YaxAB from Yersinia enterocolitica has been studied structurally. This HMM represents subunit A proteins such as XaxA and YaxA, capable of binding to the membrane even in the absence of the B subunit. This family is related to the Bacillus haemolytic enterotoxin family (see PF05791.9), although thresholds for this HMM are set to exclude that family.


Pssm-ID: 468250 [Multi-domain]  Cd Length: 340  Bit Score: 41.52  E-value: 7.05e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2036 ALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFkvlLDDTQSEAARVLADNLKLKKELQSNK----ESV 2111
Cdd:NF033928    88 PIIDLINEMPIIKRGDLTEEELSELPPIPLSSDDKEIVKELKEI---LEDLKNDIKDYQQKADDVKKELDDFEndlrEEL 164

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2112 KSQMKQKDEDLERRLEQAEEKHLKEK-KNMQEKLDALRREKVHLEETIG----------------------EIQVTLNKK 2168
Cdd:NF033928   165 LPQLKLKKKLYDDNLGSDSIEELREKiDQLEKEIEQLNKEYDDYVKLSFtglaggpiglaitggifgskaeKIRKEKNAL 244

                          170       180       190
                   ....*....|....*....|....*....|....*..
gi 1034632655 2169 DKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVID 2205
Cdd:NF033928   245 IQEIDELQEQLKKKNALLGSLERLQTSLDDILTRMED 281
 
Name Accession Description Interval E-value
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1900-2772 2.71e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 92.81  E-value: 2.71e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1900 IQEELSRVTKLKETAEEEKDDLE------ERLMNQLAELNGSIGNYCQDVTDAQ----IKNELLESEMKNLKKCVSELEE 1969
Cdd:TIGR02168  160 IFEEAAGISKYKERRKETERKLErtrenlDRLEDILNELERQLKSLERQAEKAErykeLKAELRELELALLVLRLEELRE 239

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1970 EKQQLVKEKTKVESEIR------KEYLEKIQGAQKEPGNKSHAK-ELQELLKEKQQEVKQLQKDCIRYQEKISALERTVK 2042
Cdd:TIGR02168  240 ELEELQEELKEAEEELEeltaelQELEEKLEELRLEVSELEEEIeELQKELYALANEISRLEQQKQILRERLANLERQLE 319

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2043 ALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDdtqsEAARVLADNLKLKKELQSNKESVKS---QMKQKD 2119
Cdd:TIGR02168  320 ELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELE----ELEAELEELESRLEELEEQLETLRSkvaQLELQI 395

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2120 EDLERRLEQAEEkHLKEKKNMQEKLDALRRE--KVHLEETIGEIQVTLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQ 2197
Cdd:TIGR02168  396 ASLNNEIERLEA-RLERLEDRRERLQQEIEEllKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAE 474

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2198 DDRDRVIDEAKKWERKFsDAIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELkinISRLEHDKQiWESKAQTEVQ--LQQ 2275
Cdd:TIGR02168  475 QALDAAERELAQLQARL-DSLERLQENLEGFSEGVKALLKNQSGLSGILGVL---SELISVDEG-YEAAIEAALGgrLQA 549

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2276 KVCDTLQGENKELlsqleetrhlYHSSQNELAKLE-SELKSLKDQlTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSK-- 2352
Cdd:TIGR02168  550 VVVENLNAAKKAI----------AFLKQNELGRVTfLPLDSIKGT-EIQGNDREILKNIEGFLGVAKDLVKFDPKLRKal 618

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2353 ---FSYEQLETDLQASRELTSRLHEEINM--KEQKIIS---LLSGKEEAIQVAIAELRQqhdkEIKELENLLSQEEEENI 2424
Cdd:TIGR02168  619 sylLGGVLVVDDLDNALELAKKLRPGYRIvtLDGDLVRpggVITGGSAKTNSSILERRR----EIEELEEKIEELEEKIA 694

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2425 VLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERhlsiilekdqlIQEAAAEN 2504
Cdd:TIGR02168  695 ELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKE-----------LTELEAEI 763

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2505 NKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDSQQKQLlevqlqqnKELENKYAKLEEKLKESEEANED 2584
Cdd:TIGR02168  764 EELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAEL--------TLLNEEAANLRERLESLERRIAA 835

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2585 LRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTALQEEgtlglyhaqLKVKEEEVHRLSALFSSSQKRIAELEEELvcv 2664
Cdd:TIGR02168  836 TERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESE---------LEALLNERASLEEALALLRSELEELSEEL--- 903

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2665 qKEAAKKVGEIEDK---LKKELKHLHHDAGIMRNETETAEERVAELARDLVEM-EQKLLMVTKENKGLTAQIQSFGRSMS 2740
Cdd:TIGR02168  904 -RELESKRSELRREleeLREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEaEALENKIEDDEEEARRRLKRLENKIK 982

                          890       900       910
                   ....*....|....*....|....*....|..
gi 1034632655 2741 SLQNSRDHANEELDELKRKYDASLKELAQLKE 2772
Cdd:TIGR02168  983 ELGPVNLAAIEEYEELKERYDFLTAQKEDLTE 1014
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1352-2179 2.87e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 92.81  E-value: 2.87e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1352 IESLKTVSHEAEVHAEsLQQKLESSQLQIAGLEhLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQ 1431
Cdd:TIGR02168  202 LKSLERQAEKAERYKE-LKAELRELELALLVLR-LEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSEL 279

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1432 EDLIKALHTQLEMQAKEH---DERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEALKEnksLQEELSLA 1508
Cdd:TIGR02168  280 EEEIEELQKELYALANEIsrlEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEE---LKEELESL 356

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1509 RGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMdrsllenQSLSSSCESLKLALEGLTEDKEKLVKE 1588
Cdd:TIGR02168  357 EAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEI-------ERLEARLERLEDRRERLQQEIEELLKK 429

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1589 IESLKSSKIAESTEwqekhkELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEaeq 1668
Cdd:TIGR02168  430 LEEAELKELQAELE------ELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQEN--- 500

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1669 emeemkekmrkfAKSKQQKILELEEENDRLRAEVHPAGDtakecmetLLSSNASMKEELERVkmeyetLSKKFQSLMSEk 1748
Cdd:TIGR02168  501 ------------LEGFSEGVKALLKNQSGLSGILGVLSE--------LISVDEGYEAAIEAA------LGGRLQAVVVE- 553

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1749 dSLSEEVQDLKHQIEGNVSKQANLEATEKHDNQtnvteegtqsIPGETEEQDSLSMSTRPTCSESVPSAKSANPAVSkDF 1828
Cdd:TIGR02168  554 -NLNAAKKAIAFLKQNELGRVTFLPLDSIKGTE----------IQGNDREILKNIEGFLGVAKDLVKFDPKLRKALS-YL 621

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1829 SSH----DEINNYLQQIDQLK--ERIAGLEEEkQKNKEFSQTLENEKNTllSQISTKDGELKMLQEEVTKMNLLNQQIQE 1902
Cdd:TIGR02168  622 LGGvlvvDDLDNALELAKKLRpgYRIVTLDGD-LVRPGGVITGGSAKTN--SSILERRREIEELEEKIEELEEKIAELEK 698

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1903 ELSRVTKLKETAEEEKDDLEERlmnqLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVE 1982
Cdd:TIGR02168  699 ALAELRKELEELEEELEQLRKE----LEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAE 774

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1983 SEIrKEYLEKIQGAQKEPGN-KSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEfvqtesqKDLEITKEN 2061
Cdd:TIGR02168  775 EEL-AEAEAEIEELEAQIEQlKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATE-------RRLEDLEEQ 846

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2062 LAQAVEHRKKAQAELASFKVLLDDTQSEaarvLADNLKLKKELQSNKESVKSQMKQKDEDLerrleqaeekhlkekKNMQ 2141
Cdd:TIGR02168  847 IEELSEDIESLAAEIEELEELIEELESE----LEALLNERASLEEALALLRSELEELSEEL---------------RELE 907

                          810       820       830
                   ....*....|....*....|....*....|....*...
gi 1034632655 2142 EKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQENL 2179
Cdd:TIGR02168  908 SKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERL 945
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1301-2086 5.02e-18

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 92.05  E-value: 5.02e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1301 TSVAQIKAQLKEIEAEKVELELKVSSTTSELTKKSEEVFQLQEQINKQGL-EIESLKTVSHEAEVHAESLQQKLESSQLQ 1379
Cdd:TIGR02169  237 RQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEeEQLRVKEKIGELEAEIASLERSIAEKERE 316

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1380 iaglehLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDE---RIKQL 1456
Cdd:TIGR02169  317 ------LEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAEtrdELKDY 390

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1457 QVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEALK-----------ENKSLQEELSLARGTIERLTKSLADVESQ 1525
Cdd:TIGR02169  391 REKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAgieakineleeEKEDKALEIKKQEWKLEQLAADLSKYEQE 470

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1526 VSAQNKEKDTVLGRLALLQEERDKLITEMDRSLLENQSLSSSCESLKLALEGL--------------------------- 1578
Cdd:TIGR02169  471 LYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVhgtvaqlgsvgeryataievaagnrln 550

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1579 ---TEDKEKLVKEIESLKSSKIAEST-----EWQEKHKELQKEYE-----ILL------QSYENVSNEAERIQHVVEAVr 1639
Cdd:TIGR02169  551 nvvVEDDAVAKEAIELLKRRKAGRATflplnKMRDERRDLSILSEdgvigFAVdlvefdPKYEPAFKYVFGDTLVVEDI- 629

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1640 QEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMrkFAKSKQQKILELEEENDRLRAEVhpagdtakecmetllss 1719
Cdd:TIGR02169  630 EAARRLMGKYRMVTLEGELFEKSGAMTGGSRAPRGGIL--FSRSEPAELQRLRERLEGLKREL----------------- 690

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1720 nASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQANLEatekhdnqtnvteegtqsipgetEEQ 1799
Cdd:TIGR02169  691 -SSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELE-----------------------EDL 746

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1800 DSLSmstrptcsesvpsaksanpavskdfsshDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTllSQISTK 1879
Cdd:TIGR02169  747 SSLE----------------------------QEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSH--SRIPEI 796

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1880 DGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAEEEKDDLEErlmnQLAELNGSIGNYCQDVTDAQIKNELLESEMKN 1959
Cdd:TIGR02169  797 QAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQE----QRIDLKEQIKSIEKEIENLNGKKEELEEELEE 872

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1960 LKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIR---------- 2029
Cdd:TIGR02169  873 LEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEdeeipeeels 952

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2030 ---YQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDDT 2086
Cdd:TIGR02169  953 ledVQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAILERIEEY 1012
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 758-1532 7.58e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 91.66  E-value: 7.58e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  758 VTELRAQVKQLEMNLAEAERQRRLdyesqtaHDNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQS 837
Cdd:TIGR02168  195 LNELERQLKSLERQAEKAERYKEL-------KAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEE 267

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  838 QLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISfsmtEKMVQLN 917
Cdd:TIGR02168  268 KLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELA----EELAELE 343

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  918 EEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEmspagqiskeeLQHEFDLLKKENEQRKRKLQAA 997
Cdd:TIGR02168  344 EKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQ-----------LELQIASLNNEIERLEARLERL 412

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  998 LINRKELLQRVSRLEEELANL-KDESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIYLKQTiSEKEVELQHIR 1076
Cdd:TIGR02168  413 EDRRERLQQEIEELLKKLEEAeLKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAA-ERELAQLQARL 491

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1077 KDLEEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEISENQ-----------AIIQKLITSNTDASDGDSVALVKE--- 1142
Cdd:TIGR02168  492 DSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEgyeaaieaalgGRLQAVVVENLNAAKKAIAFLKQNelg 571

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1143 TVVISPPCTGSSEHWKPELEEKI----------LALEKEKEQLQKKLQ---------EALTSRKAILKKAQEKER----- 1198
Cdd:TIGR02168  572 RVTFLPLDSIKGTEIQGNDREILkniegflgvaKDLVKFDPKLRKALSyllggvlvvDDLDNALELAKKLRPGYRivtld 651

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1199 -----------------------------HLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVRESidgklpS 1249
Cdd:TIGR02168  652 gdlvrpggvitggsaktnssilerrreieELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEEL------S 725

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1250 TDQQESCSSTPGLEEPLFKATEQHHTQPVLESNLcpdwpshseDASALQGGTSVAQIKAQLKEIEAEKVELELKV----- 1324
Cdd:TIGR02168  726 RQISALRKDLARLEAEVEQLEERIAQLSKELTEL---------EAEIEELEERLEEAEEELAEAEAEIEELEAQIeqlke 796

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1325 --SSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLEH--------LRELQPKLD 1394
Cdd:TIGR02168  797 elKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAeieeleelIEELESELE 876

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1395 ELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEmQAKEHDERIKQ------------LQVELCE 1462
Cdd:TIGR02168  877 ALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLA-QLELRLEGLEVridnlqerlseeYSLTLEE 955

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1034632655 1463 MKQKPEEIGEESRAKQQIQRKLQAALIS----RKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKE 1532
Cdd:TIGR02168  956 AEALENKIEDDEEEARRRLKRLENKIKElgpvNLAAIEEYEELKERYDFLTAQKEDLTEAKETLEEAIEEIDRE 1029
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 762-1645 2.27e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 90.12  E-value: 2.27e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  762 RAQVKQLEMNLAEAERQ-RRLDYESQTAHDNL-LTEQIHSLSIEAKSKDvkIEVLQNELDDVQLQFSEQSTLIRSLQSQL 839
Cdd:TIGR02168  185 RENLDRLEDILNELERQlKSLERQAEKAERYKeLKAELRELELALLVLR--LEELREELEELQEELKEAEEELEELTAEL 262

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  840 QNKESEvlegaervrhisskveelsqaLSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISfsmtEKMVQLNEE 919
Cdd:TIGR02168  263 QELEEK---------------------LEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILR----ERLANLERQ 317

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  920 KFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEMSPAgqisKEELQHEFDLLKKENEQRKRKLQAALI 999
Cdd:TIGR02168  318 LEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAE----LEELESRLEELEEQLETLRSKVAQLEL 393

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1000 NRKELLQRVSRLEEELANLKDESKKEiplsETERGEVEEDKENKEYSEkcvtskcqeieiyLKQTISEKEVELQHIRKDL 1079
Cdd:TIGR02168  394 QIASLNNEIERLEARLERLEDRRERL----QQEIEELLKKLEEAELKE-------------LQAELEELEEELEELQEEL 456

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1080 EEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEISENQAIIQKLITSNTDASdgdSVALVKETVVISPPCTGSSEHWKP 1159
Cdd:TIGR02168  457 ERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVK---ALLKNQSGLSGILGVLSELISVDE 533

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1160 ELEEKILALekekeqLQKKLQEALTSRKAILKKAQE------KERHLREELKQQKDDYNR-LQEQFDEQSKENENIGDQL 1232
Cdd:TIGR02168  534 GYEAAIEAA------LGGRLQAVVVENLNAAKKAIAflkqneLGRVTFLPLDSIKGTEIQgNDREILKNIEGFLGVAKDL 607

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1233 RQLQIQVRESIDGKLpstdqqescsSTPGLEEPLFKATEQHHTQPVLESNLCPD----WPSHSEDASALQGGTSVAQIKA 1308
Cdd:TIGR02168  608 VKFDPKLRKALSYLL----------GGVLVVDDLDNALELAKKLRPGYRIVTLDgdlvRPGGVITGGSAKTNSSILERRR 677

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1309 QLKEIEAEKVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLEHLRE 1388
Cdd:TIGR02168  678 EIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELT 757

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1389 lqpkldELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALhtqlemqakehDERIKQLQVELCEMKqkpE 1468
Cdd:TIGR02168  758 ------ELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKAL-----------REALDELRAELTLLN---E 817

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1469 EIGEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERD 1548
Cdd:TIGR02168  818 EAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELE 897

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1549 KLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKsSKIAEstewqekhkELQKEYEILLQSYENVSNEA 1628
Cdd:TIGR02168  898 ELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQ-ERLSE---------EYSLTLEEAEALENKIEDDE 967

                          890
                   ....*....|....*..
gi 1034632655 1629 ERIQHVVEAVRQEKQEL 1645
Cdd:TIGR02168  968 EEARRRLKRLENKIKEL 984
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2015-2783 2.37e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 89.73  E-value: 2.37e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2015 EKQQEVKQLQKDC----IRYQEKISALERTVKALEFVQTESQkdLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEA 2090
Cdd:TIGR02168  199 ERQLKSLERQAEKaeryKELKAELRELELALLVLRLEELREE--LEELQEELKEAEEELEELTAELQELEEKLEELRLEV 276

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2091 ARVLADNLKLKKELQSnkesvksqMKQKDEDLERRLEQAEEKhlkeKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDK 2170
Cdd:TIGR02168  277 SELEEEIEELQKELYA--------LANEISRLEQQKQILRER----LANLERQLEELEAQLEELESKLDELAEELAELEE 344

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2171 EVQQLQENLDStvtQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEEirlkedncSVLKDQLRQMSIHMEELK 2250
Cdd:TIGR02168  345 KLEELKEELES---LEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQI--------ASLNNEIERLEARLERLE 413

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2251 INISRLEHDKQIWESKAQ-TEVQLQQKVCDTLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEK 2329
Cdd:TIGR02168  414 DRRERLQQEIEELLKKLEeAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDS 493

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2330 CKEQKGNLEGIIRQQEADIQN-SKFSY------EQLETDLQASRELTSRLHEEINM-------KEQKIISLLSgKEEAIQ 2395
Cdd:TIGR02168  494 LERLQENLEGFSEGVKALLKNqSGLSGilgvlsELISVDEGYEAAIEAALGGRLQAvvvenlnAAKKAIAFLK-QNELGR 572

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2396 VAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETL--KTIKKENIQQKAQL--------------- 2458
Cdd:TIGR02168  573 VTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLlgGVLVVDDLDNALELakklrpgyrivtldg 652

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2459 -------------DSFVKSMSSLQNDRDRIVGDYQQLEERhlsiILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSEN 2525
Cdd:TIGR02168  653 dlvrpggvitggsAKTNSSILERRREIEELEEKIEELEEK----IAELEKALAELRKELEELEEELEQLRKELEELSRQI 728

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2526 AKLDAELIQYREDLNQVITIKDSQQKQLLEVQLQQN-------------KELENKYAKLEEKLKESEEANEDLRRSFNAL 2592
Cdd:TIGR02168  729 SALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEeleerleeaeeelAEAEAEIEELEAQIEQLKEELKALREALDEL 808

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2593 QEEKQDLSKEIESLKVSISQLTRQVTALQEEgtLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELvcvqkeaaKKV 2672
Cdd:TIGR02168  809 RAELTLLNEEAANLRERLESLERRIAATERR--LEDLEEQIEELSEDIESLAAEIEELEELIEELESEL--------EAL 878

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2673 GEIEDKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKGLTAQIQSFgrsmssLQNSRDHANEE 2752
Cdd:TIGR02168  879 LNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNL------QERLSEEYSLT 952

                          810       820       830
                   ....*....|....*....|....*....|..
gi 1034632655 2753 LDELKRKYDASLKELAQLKEQ-GLLNRERDAL 2783
Cdd:TIGR02168  953 LEEAEALENKIEDDEEEARRRlKRLENKIKEL 984
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1305-2186 8.06e-16

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 84.72  E-value: 8.06e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1305 QIKAQLKEIE-----AEKVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQ 1379
Cdd:TIGR02168  217 ELKAELRELElallvLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANE 296

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1380 IAGLEH-LRELQPKLDELQKLISKKEEdvsylsgQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQv 1458
Cdd:TIGR02168  297 ISRLEQqKQILRERLANLERQLEELEA-------QLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELE- 368

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1459 elcEMKQKPEEigeesrakqqiqrkLQAALISRKEALKEnksLQEELSLARGTIERLTKSLADVESqvsaqnkekdtvlg 1538
Cdd:TIGR02168  369 ---ELESRLEE--------------LEEQLETLRSKVAQ---LELQIASLNNEIERLEARLERLED-------------- 414

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1539 RLALLQEERDKLITEMDRSllENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQkEYEILL 1618
Cdd:TIGR02168  415 RRERLQQEIEELLKKLEEA--ELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELA-QLQARL 491

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1619 QSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRL 1698
Cdd:TIGR02168  492 DSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQAVVVENLNAAKKAIAFLKQNELG 571

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1699 RAEVHPAGDTAKECMETLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLkhqiegnvsKQANLEATEKH 1778
Cdd:TIGR02168  572 RVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDL---------DNALELAKKLR 642

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1779 DNQTNVTEEGTQSIPGETeeqdslsmstrptcsesvpSAKSANPAVSKDFSSHDEINNYLQQIDQLKERIAGLEEEKQKN 1858
Cdd:TIGR02168  643 PGYRIVTLDGDLVRPGGV-------------------ITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAEL 703

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1859 KEFSQTLENEKNTLLSQISTKDGELKMLQEEV----TKMNLLNQQIQEELSRVTKLKETAEEEKDDLEErLMNQLAELNG 1934
Cdd:TIGR02168  704 RKELEELEEELEQLRKELEELSRQISALRKDLarleAEVEQLEERIAQLSKELTELEAEIEELEERLEE-AEEELAEAEA 782

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1935 SIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKELQELLK 2014
Cdd:TIGR02168  783 EIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIE 862

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2015 EKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEIT-------KENLAQAVEHRKKAQAELASFKVLLDDTQ 2087
Cdd:TIGR02168  863 ELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELeskrselRRELEELREKLAQLELRLEGLEVRIDNLQ 942

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2088 SEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQ---------AEEKHLKEKKN-MQEKLDALRREKVHLEET 2157
Cdd:TIGR02168  943 ERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKElgpvnlaaiEEYEELKERYDfLTAQKEDLTEAKETLEEA 1022

                          890       900       910
                   ....*....|....*....|....*....|
gi 1034632655 2158 IGEI-QVTLNKKDKEVQQLQENLDSTVTQL 2186
Cdd:TIGR02168 1023 IEEIdREARERFKDTFDQVNENFQRVFPKL 1052
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2118-2954 8.99e-16

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 84.72  E-value: 8.99e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2118 KDEDLERRLEQAE--EKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLN------KKDKEVQQLQENLDSTvtQLAAF 2189
Cdd:TIGR02168  153 KPEERRAIFEEAAgiSKYKERRKETERKLERTRENLDRLEDILNELERQLKslerqaEKAERYKELKAELREL--ELALL 230

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2190 TKSMSSLQDDRDRVIDEAKKWERKFSDA---IQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELKINISRLEHDKQIWESK 2266
Cdd:TIGR02168  231 VLRLEELREELEELQEELKEAEEELEELtaeLQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRER 310

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2267 AQTEVQLQQKVCDTLQgenkELLSQLEETrhlyhssQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEA 2346
Cdd:TIGR02168  311 LANLERQLEELEAQLE----ELESKLDEL-------AEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEE 379

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2347 DIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKIISLLSGKEEAIQ----VAIAELRQQHDKEIKELENLLSQEeee 2422
Cdd:TIGR02168  380 QLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKkleeAELKELQAELEELEEELEELQEEL--- 456

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2423 nivleeenkkavdktNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEErhlsiilekdqlIQEAAA 2502
Cdd:TIGR02168  457 ---------------ERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEG------------FSEGVK 509

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2503 ENNKLKEEIRGLRSHMDDLNSENAKLDAEL-IQYREDLNQVITIKDSQQKQLLEVQLQQNKELENKYAKLEEKLKESEEA 2581
Cdd:TIGR02168  510 ALLKNQSGLSGILGVLSELISVDEGYEAAIeAALGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGN 589

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2582 NEDLRRSFNALQEEKQDLSKEIESLKVSISQLTRQV-------TALQ-----------------------------EEGT 2625
Cdd:TIGR02168  590 DREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVlvvddldNALElakklrpgyrivtldgdlvrpggvitggsAKTN 669

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2626 LGLYHAQLKVKE--EEVHRLSALFSSSQKRIAELEEELVCVQKEAAKKVGEIEDKlKKELKHLHHDAGIMRNETETAEER 2703
Cdd:TIGR02168  670 SSILERRREIEEleEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEEL-SRQISALRKDLARLEAEVEQLEER 748

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2704 VAELARDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKEQGLLNRERDAL 2783
Cdd:TIGR02168  749 IAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLES 828

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2784 LSETAFSMNSTEENSLSHLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKFRkseegkqr 2863
Cdd:TIGR02168  829 LERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELS-------- 900

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2864 saaqpstspAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELhpLKAQLQEYQDKTKAFQIMQEELRQENLS 2943
Cdd:TIGR02168  901 ---------EELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNL--QERLSEEYSLTLEEAEALENKIEDDEEE 969

                          890
                   ....*....|.
gi 1034632655 2944 WQHELHQLRME 2954
Cdd:TIGR02168  970 ARRRLKRLENK 980
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1303-2172 3.04e-15

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 82.81  E-value: 3.04e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1303 VAQIKAQLKEIEAEKVELELKVSSTTSELTKKSEEVFQLQEQINKQgLEIESLKTVSHEAEVHA-----ESLQQKLESSQ 1377
Cdd:TIGR02169  165 VAEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKA-ERYQALLKEKREYEGYEllkekEALERQKEAIE 243

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1378 LQIAGLE-HLRELQPKLDELQKLISKKEEDVSYLSGQLSEK-EAALTKIQTEIIEQEDLIKALHTQL---EMQAKEHDER 1452
Cdd:TIGR02169  244 RQLASLEeELEKLTEEISELEKRLEEIEQLLEELNKKIKDLgEEEQLRVKEKIGELEAEIASLERSIaekERELEDAEER 323

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1453 IKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEalkenkslqeELSLARGTIERLTKSLADVESQVSAQNKE 1532
Cdd:TIGR02169  324 LAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKE----------ELEDLRAELEEVDKEFAETRDELKDYREK 393

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1533 KDTvlgrlalLQEERDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDkeklVKEIESLKSSKIAESTEWQEKHKELQK 1612
Cdd:TIGR02169  394 LEK-------LKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAK----INELEEEKEDKALEIKKQEWKLEQLAA 462

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1613 EYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELE 1692
Cdd:TIGR02169  463 DLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIE 542

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1693 -EENDRLRAEVHPAGDTAKECMETLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVqDLKHQIEgNVSKQA- 1770
Cdd:TIGR02169  543 vAAGNRLNNVVVEDDAVAKEAIELLKRRKAGRATFLPLNKMRDERRDLSILSEDGVIGFAVDLV-EFDPKYE-PAFKYVf 620

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1771 -------NLEATEKH-DNQTNVTEEGtqsipgeteeqDSLSMSTRPTCSESVPSAKSANPAvskdfsshdeinNYLQQID 1842
Cdd:TIGR02169  621 gdtlvveDIEAARRLmGKYRMVTLEG-----------ELFEKSGAMTGGSRAPRGGILFSR------------SEPAELQ 677

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1843 QLKERIAGLEEEKQKNKEFSQTLENEKNTLLS-------QISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAE 1915
Cdd:TIGR02169  678 RLRERLEGLKRELSSLQSELRRIENRLDELSQelsdasrKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVK 757

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1916 EEKDDLEERlmnqLAELNGSIGNYCQDVTDaqIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQG 1995
Cdd:TIGR02169  758 SELKELEAR----IEELEEDLHKLEEALND--LEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYL 831

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1996 AQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAE 2075
Cdd:TIGR02169  832 EKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQ 911

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2076 LASFKVLLDDTQsEAARVLADNLK----LKKELQSNKESVKS--QMKQKDEDLERRLEQAE----------EKHLKEKKN 2139
Cdd:TIGR02169  912 IEKKRKRLSELK-AKLEALEEELSeiedPKGEDEEIPEEELSleDVQAELQRVEEEIRALEpvnmlaiqeyEEVLKRLDE 990

                          890       900       910
                   ....*....|....*....|....*....|...
gi 1034632655 2140 MQEKLDALRREKVHLEETIGEiqvtLNKKDKEV 2172
Cdd:TIGR02169  991 LKEKRAKLEEERKAILERIEE----YEKKKREV 1019
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 190-1018 3.62e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 82.80  E-value: 3.62e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  190 QQLQEKEEFISTLQAQLSQTQAEQAaqvvREKDARFETQVRLHEDELLQLVTQADVETEMQQKLRVLQRKLEEHEESLVG 269
Cdd:TIGR02168  213 ERYKELKAELRELELALLVLRLEEL----REELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQK 288

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  270 RaqvVDLLQQELTAAEQRNQILSQQLQQMEAEhntlRNTVETEREESKILLEKMELEVAERKLSFHNLQEEMHHLLEQFE 349
Cdd:TIGR02168  289 E---LYALANEISRLEQQKQILRERLANLERQ----LEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELE 361

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  350 QAGQAQAELESRYSALEQKHkaemeektshilslqktgQELQSACDALKDQNSKLlqdkNEQAVQSAQTIQQLEDQLQQK 429
Cdd:TIGR02168  362 ELEAELEELESRLEELEEQL------------------ETLRSKVAQLELQIASL----NNEIERLEARLERLEDRRERL 419

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  430 SKEISQFLNRLPLQQHETASQTSfpdvynEGTQAVTEENIASLQKRVVELENEKGALLLSSIELEELKAENEKLSSQITL 509
Cdd:TIGR02168  420 QQEIEELLKKLEEAELKELQAEL------EELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDS 493

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  510 LEA-QNRTGEADREVSEI---------------SIVDIANKRSSSAE----ESGQDVLENTFSQKHKELSVLLlemKEAQ 569
Cdd:TIGR02168  494 LERlQENLEGFSEGVKALlknqsglsgilgvlsELISVDEGYEAAIEaalgGRLQAVVVENLNAAKKAIAFLK---QNEL 570

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  570 EEIAFLKLQLQGKRAEEADHEVLdQKEMKQMEGEGIAPIKMKVFLEDTGQDFplmpneESSLPAVEKEQASTEHQSRTSE 649
Cdd:TIGR02168  571 GRVTFLPLDSIKGTEIQGNDREI-LKNIEGFLGVAKDLVKFDPKLRKALSYL------LGGVLVVDDLDNALELAKKLRP 643

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  650 EISLNDAGVELKS-----TKQDGDKSLSAvpdigQCHQDELERLKSQILELELNFHKAqeiyEKNLDEKAKEISNLNQLI 724
Cdd:TIGR02168  644 GYRIVTLDGDLVRpggviTGGSAKTNSSI-----LERRREIEELEEKIEELEEKIAEL----EKALAELRKELEELEEEL 714

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  725 EEFKKNADNNSSAFTALSEERDQLLSQVKELSmvtelrAQVKQLEMNLAEAERQRrldyesqtahdNLLTEQIHSLSIEA 804
Cdd:TIGR02168  715 EQLRKELEELSRQISALRKDLARLEAEVEQLE------ERIAQLSKELTELEAEI-----------EELEERLEEAEEEL 777

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  805 KSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEK 884
Cdd:TIGR02168  778 AEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESL 857

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  885 KRDVETLQQTIEEKDQQVTEISF---SMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQN 961
Cdd:TIGR02168  858 AAEIEELEELIEELESELEALLNeraSLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVR 937

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1034632655  962 YDEMspAGQISkEELQHEFDLLKKENEQRKRKLQaalinrkELLQRVSRLEEELANL 1018
Cdd:TIGR02168  938 IDNL--QERLS-EEYSLTLEEAEALENKIEDDEE-------EARRRLKRLENKIKEL 984
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1831-2528 4.62e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 82.41  E-value: 4.62e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1831 HDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKL 1910
Cdd:TIGR02168  238 REELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQ 317

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1911 KETAEEEKDDLEERLMNQLAELNGS---IGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRK 1987
Cdd:TIGR02168  318 LEELEAQLEELESKLDELAEELAELeekLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIAS 397

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1988 EYLE-KIQGAQKEPGNKSHAKELQELLK-EKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTEsqkdLEITKENLAQA 2065
Cdd:TIGR02168  398 LNNEiERLEARLERLEDRRERLQQEIEElLKKLEEAELKELQAELEELEEELEELQEELERLEEA----LEELREELEEA 473

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2066 VEHRKKAQAELASFKVLLDDTQSEAARVL-----ADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLK----E 2136
Cdd:TIGR02168  474 EQALDAAERELAQLQARLDSLERLQENLEgfsegVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQavvvE 553

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2137 KKNMQEK-LDALRREKVH----LEETI---GEIQVTLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSL------QDDRDR 2202
Cdd:TIGR02168  554 NLNAAKKaIAFLKQNELGrvtfLPLDSikgTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLlggvlvVDDLDN 633

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2203 VIDEAKKW-----------------------ERKFSDAIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELKINISRLE-- 2257
Cdd:TIGR02168  634 ALELAKKLrpgyrivtldgdlvrpggvitggSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEee 713

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2258 ---------------HDKQIWESKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTD 2322
Cdd:TIGR02168  714 leqlrkeleelsrqiSALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQ 793

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2323 LSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKIISLlsgkeeaiQVAIAELR 2402
Cdd:TIGR02168  794 LKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESL--------AAEIEELE 865

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2403 QQHDKEIKELENLLSQEEEENIVLEEENKKAvdktNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQL 2482
Cdd:TIGR02168  866 ELIEELESELEALLNERASLEEALALLRSEL----EELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNL 941

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*..
gi 1034632655 2483 EERhlsiILEKDQLIQEAAAEN-NKLKEEIRGLRSHMDDLNSENAKL 2528
Cdd:TIGR02168  942 QER----LSEEYSLTLEEAEALeNKIEDDEEEARRRLKRLENKIKEL 984
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1833-2378 1.49e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 77.28  E-value: 1.49e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1833 EINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVtkmNLLNQQIQEELSRVTKLKE 1912
Cdd:COG1196    233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEE---YELLAELARLEQDIARLEE 309

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1913 TAEEEKDDLEeRLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEK 1992
Cdd:COG1196    310 RRRELEERLE-ELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEEL 388

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1993 IQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKA 2072
Cdd:COG1196    389 LEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAEL 468

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2073 QAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKN----MQEKLDALR 2148
Cdd:COG1196    469 LEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAyeaaLEAALAAAL 548

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2149 REKVHLEETIGEIQVTLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEEIRLK 2228
Cdd:COG1196    549 QNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLV 628

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2229 EDNC-------SVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHS 2301
Cdd:COG1196    629 AARLeaalrraVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERE 708

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1034632655 2302 SQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLhEEINM 2378
Cdd:COG1196    709 LAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEAL-GPVNL 784
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1837-2620 1.53e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 77.40  E-value: 1.53e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1837 YLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAEE 1916
Cdd:TIGR02168  230 LVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRE 309

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1917 EKDDLEerlmNQLAELNGSIgnycqdvtdaqiknELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEylekiqgA 1996
Cdd:TIGR02168  310 RLANLE----RQLEELEAQL--------------EELESKLDELAEELAELEEKLEELKEELESLEAELEEL-------E 364

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1997 QKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEfvqTESQKDLEITKENLAQAVEHRKKA-QAE 2075
Cdd:TIGR02168  365 AELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLE---DRRERLQQEIEELLKKLEEAELKElQAE 441

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2076 LASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKS------QMKQKDEDLERRLEQAEEKHLKEKKNMQEKLD---- 2145
Cdd:TIGR02168  442 LEELEEELEELQEELERLEEALEELREELEEAEQALDAaerelaQLQARLDSLERLQENLEGFSEGVKALLKNQSGlsgi 521

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2146 -ALRREKVH--------LEETIGE-----IQVTLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRD---------- 2201
Cdd:TIGR02168  522 lGVLSELISvdegyeaaIEAALGGrlqavVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDReilkniegfl 601

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2202 RVIDEAKKWERKFSDAIQSKEEEIRLKEDNCSVLkDQLRQM------------------SIHMEELKINISRLEHDKQIW 2263
Cdd:TIGR02168  602 GVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNAL-ELAKKLrpgyrivtldgdlvrpggVITGGSAKTNSSILERRREIE 680

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2264 ESKAQtevqlqqkvCDTLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQ 2343
Cdd:TIGR02168  681 ELEEK---------IEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQ 751

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2344 QEADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKIisllsgkeEAIQVAIAELRQQHDKEIKELENLLSQEEEEN 2423
Cdd:TIGR02168  752 LSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQI--------EQLKEELKALREALDELRAELTLLNEEAANLR 823

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2424 IVLEEENKKAVDKTNQLMETLKTIKKENIQQK---AQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSIILEKDQL---I 2497
Cdd:TIGR02168  824 ERLESLERRIAATERRLEDLEEQIEELSEDIEslaAEIEELEELIEELESELEALLNERASLEEALALLRSELEELseeL 903

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2498 QEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLN--QVITIKDSQQKQLLEVQLQQN-----KELENKYAK 2570
Cdd:TIGR02168  904 RELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSeeYSLTLEEAEALENKIEDDEEEarrrlKRLENKIKE 983

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2571 LEEKLKESEEANEDLRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTAL 2620
Cdd:TIGR02168  984 LGPVNLAAIEEYEELKERYDFLTAQKEDLTEAKETLEEAIEEIDREARER 1033
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1369-1936 2.40e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 76.51  E-value: 2.40e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1369 LQQKLESSQLQIAGLeHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKE 1448
Cdd:COG1196    218 LKEELKELEAELLLL-KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAE 296

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1449 HDERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSA 1528
Cdd:COG1196    297 LARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAE 376

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1529 QNKEKDTVLGRLALLQEERDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAEstewQEKHK 1608
Cdd:COG1196    377 AEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEA----AEEEA 452

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1609 ELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETE------KQLQEAEQEMEEMKEKMRKFAK 1682
Cdd:COG1196    453 ELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEgflegvKAALLLAGLRGLAGAVAVLIGV 532

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1683 SKQQKILELEEENDRLRAEVHPAGDTAKECMETLLSSNASMKEELERVKMEYETLSKKFQSLM----------SEKDSLS 1752
Cdd:COG1196    533 EAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGaigaavdlvaSDLREAD 612

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1753 EEVQDLKHQIEGNVSKQANLEATEKHDNQTN-----VTEEGTQSIPGETEEQDSLSMSTRPTCSESVPSAKSANPAVSKD 1827
Cdd:COG1196    613 ARYYVLGDTLLGRTLVAARLEAALRRAVTLAgrlreVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEE 692

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1828 FSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRV 1907
Cdd:COG1196    693 LELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERL 772

                          570       580       590
                   ....*....|....*....|....*....|....*....
gi 1034632655 1908 TKLKE-------TAEEEKDDLEER---LMNQLAELNGSI 1936
Cdd:COG1196    773 EREIEalgpvnlLAIEEYEELEERydfLSEQREDLEEAR 811
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1305-1594 7.77e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 74.97  E-value: 7.77e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1305 QIKAQLKEIEAEKVELELKvssttsELTKKSEEvfqLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGL- 1383
Cdd:COG1196    217 ELKEELKELEAELLLLKLR------ELEAELEE---LEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAq 287

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1384 EHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVELCEM 1463
Cdd:COG1196    288 AEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEAL 367

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1464 KQKPEEIGEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALL 1543
Cdd:COG1196    368 LEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEA 447

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1034632655 1544 QEERDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKS 1594
Cdd:COG1196    448 AEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLE 498
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 793-1763 8.77e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 74.71  E-value: 8.77e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  793 LTEQIHSLSIEAKsKDVKIEVLQNELDDVQLQFSEQStlIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKEL 872
Cdd:TIGR02168  198 LERQLKSLERQAE-KAERYKELKAELRELELALLVLR--LEELREELEELQEELKEAEEELEELTAELQELEEKLEELRL 274

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  873 EITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISfsmtEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDN 952
Cdd:TIGR02168  275 EVSELEEEIEELQKELYALANEISRLEQQKQILR----ERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELK 350

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  953 EVSSGLKQNYDEMSPAgqisKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELANLKDESKKEiplsETE 1032
Cdd:TIGR02168  351 EELESLEAELEELEAE----LEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERL----QQE 422

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1033 RGEVEEDKENKEYSEkcvtskcqeieiyLKQTISEKEVELQHIRKDLEEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQA 1112
Cdd:TIGR02168  423 IEELLKKLEEAELKE-------------LQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQA 489

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1113 EISENQAIIQKLITSNTDASdgdSVALVKETVVISPPCTGSSEHWKPELEEKILALekekeqLQKKLQEALTSRKAILKK 1192
Cdd:TIGR02168  490 RLDSLERLQENLEGFSEGVK---ALLKNQSGLSGILGVLSELISVDEGYEAAIEAA------LGGRLQAVVVENLNAAKK 560

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1193 AQEkerhlreelkqqkddynrlqeqFDEQSKenenigdqLRQLQIQVRESIDGKLPSTDQQESCSSTPGLEEPLfkateq 1272
Cdd:TIGR02168  561 AIA----------------------FLKQNE--------LGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVA------ 604

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1273 hhtqpvleSNLCPDWPSHSEDASALQGGTSVAQIKAQLKEIEAEKVELELKVSSTTseltkkseevfqlqEQINKQGLei 1352
Cdd:TIGR02168  605 --------KDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKKLRPGYRIVTLDG--------------DLVRPGGV-- 660

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1353 eslkTVSHEAEVHAESLQQKLEssqlqiaglehLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQE 1432
Cdd:TIGR02168  661 ----ITGGSAKTNSSILERRRE-----------IEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELS 725

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1433 DLIKALHTQLEMQAKEHDERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLqaalisrKEALKENKSLQEELSLARGTI 1512
Cdd:TIGR02168  726 RQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEEL-------AEAEAEIEELEAQIEQLKEEL 798

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1513 ERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESL 1592
Cdd:TIGR02168  799 KALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEAL 878

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1593 ksskiaestewQEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEkqlqeaeqemee 1672
Cdd:TIGR02168  879 -----------LNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLE------------ 935

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1673 mkekmrkfakskqqkiLELEEENDRLRAEVHPAGDTAKECMETLLSSNASMKEELERVKM--------------EYETLS 1738
Cdd:TIGR02168  936 ----------------VRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENkikelgpvnlaaieEYEELK 999

                          970       980
                   ....*....|....*....|....*
gi 1034632655 1739 KKFQSLMSEKDSLSEEVQDLKHQIE 1763
Cdd:TIGR02168 1000 ERYDFLTAQKEDLTEAKETLEEAIE 1024
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2453-3186 2.41e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 73.55  E-value: 2.41e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2453 QQKAQLDSFVKSMSSLQNDRDRIVGDYQQLE---ERHLSIILEKDQLIQEA-------AAENNKLKEEIRGLRSHMDDLN 2522
Cdd:TIGR02168  236 ELREELEELQEELKEAEEELEELTAELQELEeklEELRLEVSELEEEIEELqkelyalANEISRLEQQKQILRERLANLE 315

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2523 SENAKLDAELIQYREDLNQVITIKDSQQKQLLEVQ------LQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEK 2596
Cdd:TIGR02168  316 RQLEELEAQLEELESKLDELAEELAELEEKLEELKeeleslEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQI 395

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2597 QDLSKEIESLKVSISQLTRQVTALQEE-----------------GTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEE 2659
Cdd:TIGR02168  396 ASLNNEIERLEARLERLEDRRERLQQEieellkkleeaelkelqAELEELEEELEELQEELERLEEALEELREELEEAEQ 475

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2660 ELVCVQKEAAKKVGEIED----------------KLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTK 2723
Cdd:TIGR02168  476 ALDAAERELAQLQARLDSlerlqenlegfsegvkALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQAVVVENL 555

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2724 ENKGLTAQIQ---SFGRSMSSLQNSRDHA-----NEELDELKRKYDASLKELAQLKEQglLNRERDALLSETAFSMNSTE 2795
Cdd:TIGR02168  556 NAAKKAIAFLkqnELGRVTFLPLDSIKGTeiqgnDREILKNIEGFLGVAKDLVKFDPK--LRKALSYLLGGVLVVDDLDN 633

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2796 ENSLSHLEKLNQQLLSKDEQLLHLSSQLedsYNQVQSFSKAMASLQNERDHLWNELEKFRkseegkqrsaaqpstspAEV 2875
Cdd:TIGR02168  634 ALELAKKLRPGYRIVTLDGDLVRPGGVI---TGGSAKTNSSILERRREIEELEEKIEELE-----------------EKI 693

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2876 QSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELHPLKAQLQEYQDKTkAFQIMQEELRQENLSWQHELHQLRMEK 2955
Cdd:TIGR02168  694 AELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQL-EERIAQLSKELTELEAEIEELEERLEE 772

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2956 SSWEIHERRMKEQYLMAisDKDQQLSHLQNLIRELRSSSSQTQPLKVQYQRQASpetsaspdGSQNLVYETELLRTQLND 3035
Cdd:TIGR02168  773 AEEELAEAEAEIEELEA--QIEQLKEELKALREALDELRAELTLLNEEAANLRE--------RLESLERRIAATERRLED 842

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 3036 SLKEIHQKELRIQQLNSNFSQLLEEKNTLSIQLCDTSQSLRENQQHYGDLLNHcavLEKQVQELQAVSKEKGPLNIDvap 3115
Cdd:TIGR02168  843 LEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSE---LEELSEELRELESKRSELRRE--- 916

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1034632655 3116 gapqekngvhRKSDPEELREPQQSFSEAQQQLCNTRQEVNELRKLLEEERDQRVAA-ENALSVAEEQIRRLE 3186
Cdd:TIGR02168  917 ----------LEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKiEDDEEEARRRLKRLE 978
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1964-2788 2.55e-12

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 73.18  E-value: 2.55e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1964 VSELEEEKQQLVKEKTKVESEIRKEYL---EKIQGAQKEPGNKSHAKELQELLKEKQQ-EVKQLQKDCIRYQEKISALER 2039
Cdd:TIGR02169  165 VAEFDRKKEKALEELEEVEENIERLDLiidEKRQQLERLRREREKAERYQALLKEKREyEGYELLKEKEALERQKEAIER 244

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2040 TVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELAsfkvllDDTQSEAARVLADNLKLKKELQSNKESVKSQmKQKD 2119
Cdd:TIGR02169  245 QLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIK------DLGEEEQLRVKEKIGELEAEIASLERSIAEK-EREL 317

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2120 EDLERRLEQAEE---KHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNK-------KDKEVQQLQENLDSTVTQLAAF 2189
Cdd:TIGR02169  318 EDAEERLAKLEAeidKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDlraeleeVDKEFAETRDELKDYREKLEKL 397

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2190 TKSMSSLQDDRDRVIDEAKKWERKFSDAiqskEEEIRLKEDNCSVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQT 2269
Cdd:TIGR02169  398 KREINELKRELDRLQEELQRLSEELADL----NAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYD 473

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2270 EVQLQQKVCDTLQGENKElLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQ---------KGNLEGI 2340
Cdd:TIGR02169  474 LKEEYDRVEKELSKLQRE-LAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERyataievaaGNRLNNV 552

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2341 IRQQEADIQN----------SKFSYEQLeTDLQASRELTSRLHE-----------EINMKEQKII-----------SLLS 2388
Cdd:TIGR02169  553 VVEDDAVAKEaiellkrrkaGRATFLPL-NKMRDERRDLSILSEdgvigfavdlvEFDPKYEPAFkyvfgdtlvveDIEA 631

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2389 GKEEAIQVAIAELrqqhDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKEniqqkaqLDSFVKSMSSL 2468
Cdd:TIGR02169  632 ARRLMGKYRMVTL----EGELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRE-------LSSLQSELRRI 700

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2469 QNDRDRIVGDYQQLEERHLSIILEKDQLIQEAAAENNKLKE---EIRGLRSHMDDLNSENAKLDAELIQYREDLNQVITI 2545
Cdd:TIGR02169  701 ENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEEleeDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEA 780

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2546 KDSQQKQLLEVQLQqnkELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTALQEE-- 2623
Cdd:TIGR02169  781 LNDLEARLSHSRIP---EIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEie 857

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2624 ---GTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELvcvqKEAAKKVGEIEDKLKKELKHLhhdaGIMRNETETA 2700
Cdd:TIGR02169  858 nlnGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQL----RELERKIEELEAQIEKKRKRL----SELKAKLEAL 929

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2701 EERVAELARDLVEMEQKLLMVTKENKgLTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKEqgllnrER 2780
Cdd:TIGR02169  930 EEELSEIEDPKGEDEEIPEEELSLED-VQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEE------ER 1002


                   ....*...
gi 1034632655 2781 DALLSETA 2788
Cdd:TIGR02169 1003 KAILERIE 1010
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1569-2377 9.61e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 71.63  E-value: 9.61e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1569 ESLKLALegLTEDKEKLVKEIESLKSSKIAESTEW---QEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQEL 1645
Cdd:TIGR02168  223 RELELAL--LVLRLEELREELEELQEELKEAEEELeelTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRL 300

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1646 YGKLRSTEANKKETEKQLQEAEQEMEEMkekmrkfakskQQKILELEEENDRLRAEVhpagDTAKECMETLLSSNASMKE 1725
Cdd:TIGR02168  301 EQQKQILRERLANLERQLEELEAQLEEL-----------ESKLDELAEELAELEEKL----EELKEELESLEAELEELEA 365

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1726 ELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQANLEAtEKHDNQTNVTEEGTQSIPGETEEQDSLSMS 1805
Cdd:TIGR02168  366 ELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLED-RRERLQQEIEELLKKLEEAELKELQAELEE 444

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1806 TRPTCSESVPSAKSANPAVSKDFSSHDEINNYLQ----QIDQLKERIAGLEEEKQKNKEFSQTLENEKN----------T 1871
Cdd:TIGR02168  445 LEEELEELQEELERLEEALEELREELEEAEQALDaaerELAQLQARLDSLERLQENLEGFSEGVKALLKnqsglsgilgV 524

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1872 LLSQISTKDG---------ELKMLQEEVTKMNLLNQQI----QEELSRVTKLKETAEEEkDDLEERLMNQLAELNGSIGn 1938
Cdd:TIGR02168  525 LSELISVDEGyeaaieaalGGRLQAVVVENLNAAKKAIaflkQNELGRVTFLPLDSIKG-TEIQGNDREILKNIEGFLG- 602

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1939 YCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHA---------KEL 2009
Cdd:TIGR02168  603 VAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKKLRPGYRIVTLDGDLVRPGGVITGGSAKTNSsilerrreiEEL 682

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2010 QELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASfkvlLDDTQSE 2089
Cdd:TIGR02168  683 EEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQ----LSKELTE 758

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2090 AARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHlKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKD 2169
Cdd:TIGR02168  759 LEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALR-EALDELRAELTLLNEEAANLRERLESLERRIAATE 837

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2170 KEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVIDEAKKWerkfSDAIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEEL 2249
Cdd:TIGR02168  838 RRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEAL----LNERASLEEALALLRSELEELSEELRELESKRSEL 913

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2250 KINISRL-EHDKQIWESKAQTEVQLQQkvcdTLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSN--- 2325
Cdd:TIGR02168  914 RRELEELrEKLAQLELRLEGLEVRIDN----LQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKELGPvnl 989

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1034632655 2326 -SLEKCKEQKGNLEgIIRQQEADIQNSKFSYEQLETDLqaSRELTSRLHEEIN 2377
Cdd:TIGR02168  990 aAIEEYEELKERYD-FLTAQKEDLTEAKETLEEAIEEI--DREARERFKDTFD 1039
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1164-1987 1.47e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 70.86  E-value: 1.47e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1164 KILALEKEKEQLQKKLQEALTSRKAILKKAQEKErhlrEELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVREsi 1243
Cdd:TIGR02168  233 RLEELREELEELQEELKEAEEELEELTAELQELE----EKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQI-- 306

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1244 dgklpstdQQESCSSTPGLEEPLFKATEQHHTQPVLESNLCPDWPSHSEDASAlqggtSVAQIKAQLKEIEAEKVELELK 1323
Cdd:TIGR02168  307 --------LRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKE-----ELESLEAELEELEAELEELESR 373

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1324 VSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLEhLRELQPKLDELQKLISKK 1403
Cdd:TIGR02168  374 LEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAE-LKELQAELEELEEELEEL 452

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1404 EEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMqAKEHDERIKQLQVELCEMKQKPEEI-GEESRAKQQIQR 1482
Cdd:TIGR02168  453 QEELERLEEALEELREELEEAEQALDAAERELAQLQARLDS-LERLQENLEGFSEGVKALLKNQSGLsGILGVLSELISV 531

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1483 K--------------LQAALISRKEALKENKSLQEELSLARGTIERLT-KSLADVESQVSAQNKEKDTVLGRLALLQEER 1547
Cdd:TIGR02168  532 DegyeaaieaalggrLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDsIKGTEIQGNDREILKNIEGFLGVAKDLVKFD 611

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1548 DKLITEMDRSLlenqSLSSSCESLKLALEGL----------TEDKEKL---------VKEIESLKSSKIAESTEWQEKHK 1608
Cdd:TIGR02168  612 PKLRKALSYLL----GGVLVVDDLDNALELAkklrpgyrivTLDGDLVrpggvitggSAKTNSSILERRREIEELEEKIE 687

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1609 ELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKI 1688
Cdd:TIGR02168  688 ELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELE 767

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1689 LELEEENDRLrAEVHPAGDTAKECMETLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEgnvsk 1768
Cdd:TIGR02168  768 ERLEEAEEEL-AEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLE----- 841

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1769 qanlEATEKHDNQTNVTEEGTQSIPGETEEQDSLsmstrptcsesvpsaksanpavskdfssHDEINNYLQQIDQLKERI 1848
Cdd:TIGR02168  842 ----DLEEQIEELSEDIESLAAEIEELEELIEEL----------------------------ESELEALLNERASLEEAL 889

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1849 AGLEEEKQKnkefsqtLENEKNTLLSQISTKDGELKMLQEEVTKMNL----LNQQIQEELSRVTKLKETAEEEKDDLEER 1924
Cdd:TIGR02168  890 ALLRSELEE-------LSEELRELESKRSELRRELEELREKLAQLELrlegLEVRIDNLQERLSEEYSLTLEEAEALENK 962

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1034632655 1925 LMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRK 1987
Cdd:TIGR02168  963 IEDDEEEARRRLKRLENKIKELGPVNLAAIEEYEELKERYDFLTAQKEDLTEAKETLEEAIEE 1025
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 808-1649 2.12e-11

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 70.48  E-value: 2.12e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  808 DVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEvLEGAERVRHISSKVEELSQALSQKELEitKMDQLLLEKKRD 887
Cdd:TIGR02169  169 DRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRRE-REKAERYQALLKEKREYEGYELLKEKE--ALERQKEAIERQ 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  888 VETLQQTIEEKDQQVTEISFSMTEKMVQLNE-----------EKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSS 956
Cdd:TIGR02169  246 LASLEEELEKLTEEISELEKRLEEIEQLLEElnkkikdlgeeEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLA 325

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  957 GLKQNYDEMspagQISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELANLKDESK---KEIPLSETER 1033
Cdd:TIGR02169  326 KLEAEIDKL----LAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKdyrEKLEKLKREI 401

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1034 GEVEEDKENKEYSEKCVTSKCQEIEIYLKQtISEKEVELQHIRKDLEEKLAAEE----QFQALVKQMNQTLQDKTNQIDL 1109
Cdd:TIGR02169  402 NELKRELDRLQEELQRLSEELADLNAAIAG-IEAKINELEEEKEDKALEIKKQEwkleQLAADLSKYEQELYDLKEEYDR 480

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1110 LQAEISENQAIIQKLITSNTDASD--GDSVALVKETVVISPPCTGSSEHWKPELEEKILALEK-----------EKEQLQ 1176
Cdd:TIGR02169  481 VEKELSKLQRELAEAEAQARASEErvRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEVaagnrlnnvvvEDDAVA 560

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1177 KKLQEALTSRKA------ILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKE--NENIGDQL--------RQLQIQVR 1240
Cdd:TIGR02169  561 KEAIELLKRRKAgratflPLNKMRDERRDLSILSEDGVIGFAVDLVEFDPKYEPafKYVFGDTLvvedieaaRRLMGKYR 640

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1241 E-SIDGKLpstdQQESCSSTPGLEEPLFKATEQHHTQPVLESnLCPDWPSHSEDASALQGGTS-----VAQIKAQLKEIE 1314
Cdd:TIGR02169  641 MvTLEGEL----FEKSGAMTGGSRAPRGGILFSRSEPAELQR-LRERLEGLKRELSSLQSELRrienrLDELSQELSDAS 715

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1315 AEKVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLEHlRELQPKLD 1394
Cdd:TIGR02169  716 RKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEA-RLSHSRIP 794

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1395 ELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEmqakEHDERIKQLQVELCEMKQKPEEIGEES 1474
Cdd:TIGR02169  795 EIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRI----DLKEQIKSIEKEIENLNGKKEELEEEL 870

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1475 RAKQQIQRKLQAALISRKealKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERdklitem 1554
Cdd:TIGR02169  871 EELEAALRDLESRLGDLK---KERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPK------- 940

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1555 dRSLLENQSLSSSCESLKLALEGLTEDKEKL----VKEIESLKSSKiAESTEWQEKHKELQKEYEILLQSYENVSNEAER 1630
Cdd:TIGR02169  941 -GEDEEIPEEELSLEDVQAELQRVEEEIRALepvnMLAIQEYEEVL-KRLDELKEKRAKLEEERKAILERIEEYEKKKRE 1018

                          890       900
                   ....*....|....*....|
gi 1034632655 1631 I-QHVVEAVRQEKQELYGKL 1649
Cdd:TIGR02169 1019 VfMEAFEAINENFNEIFAEL 1038
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2006-2606 2.84e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 69.97  E-value: 2.84e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2006 AKELQELLKEKQQEVKQLQKDciRYQEKISALERTVKALEfvqtesqkdleitkENLAQAVEHRKKAQAELASFKVLLDD 2085
Cdd:COG1196    215 YRELKEELKELEAELLLLKLR--ELEAELEELEAELEELE--------------AELEELEAELAELEAELEELRLELEE 278

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2086 TQSEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLER--RLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQV 2163
Cdd:COG1196    279 LELELEEAQAEEYELLAELARLEQDIARLEERRRELEERleELEEELAELEEELEELEEELEELEEELEEAEEELEEAEA 358

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2164 TLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRvideakkwerkfsdaIQSKEEEIRLKEDNCSVLKDQLRQMS 2243
Cdd:COG1196    359 ELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAE---------------LAAQLEELEEAEEALLERLERLEEEL 423

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2244 IHMEELKINISRLEHDKQIWESKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDL 2323
Cdd:COG1196    424 EELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADY 503

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2324 SNSLEKCKEQKGNLE-GIIRQQEADIQNSKFSYEQ-LETDLQASRELTSRLHEEInmkEQKIISLLSGKEEAiQVAIAEL 2401
Cdd:COG1196    504 EGFLEGVKAALLLAGlRGLAGAVAVLIGVEAAYEAaLEAALAAALQNIVVEDDEV---AAAAIEYLKAAKAG-RATFLPL 579

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2402 RQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLktikKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQ 2481
Cdd:COG1196    580 DKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTL----LGRTLVAARLEAALRRAVTLAGRLREVTLEGEG 655

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2482 LEERHLSIILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDsQQKQLLEVQLQQN 2561
Cdd:COG1196    656 GSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEEL-EEEALEEQLEAER 734

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*
gi 1034632655 2562 KELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSKEIESL 2606
Cdd:COG1196    735 EELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEAL 779
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 758-1119 3.63e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 69.58  E-value: 3.63e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  758 VTELRAQVKQLEmnlAEAERQRRldYesqtahdnllteqihsLSIEAKSKDVKIEVLQNELDDVQLQfseqstlIRSLQS 837
Cdd:COG1196    195 LGELERQLEPLE---RQAEKAER--Y----------------RELKEELKELEAELLLLKLRELEAE-------LEELEA 246

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  838 QLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLN 917
Cdd:COG1196    247 ELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELA 326

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  918 EEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEMSPAGQISKEELQHEFDLLKKENEQRKRkLQAA 997
Cdd:COG1196    327 ELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQ-LEEL 405

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  998 LINRKELLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKENKEysekcvtskcqeieiylkqtisEKEVELQHIRK 1077
Cdd:COG1196    406 EEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEA----------------------ELEEEEEALLE 463

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|..
gi 1034632655 1078 DLEEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEISENQA 1119
Cdd:COG1196    464 LLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEG 505
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 48-924 6.74e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 68.54  E-value: 6.74e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655   48 EDVQERLAYAEQLVVELKDIIRQKDVQLqqkdEALQEERKAADNKIKKLKLHAKAKLTSLNKYIEEMKAQGGTVLPTEPQ 127
Cdd:TIGR02168  175 KETERKLERTRENLDRLEDILNELERQL----KSLERQAEKAERYKELKAELRELELALLVLRLEELREELEELQEELKE 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  128 SEEQLSKHDKSSTEEEMEIEKIKHKLQEKEELISTLQAQLTQAQAEQpaqsstemEEFVMMKQQLQEKEEFISTLQAQLS 207
Cdd:TIGR02168  251 AEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEI--------SRLEQQKQILRERLANLERQLEELE 322

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  208 QTQAEQAAQvvREKDARFETQVRLHEDELLQLVTQADVE-TEMQQKLRVLQRKLEEHEESLVGRAQVVDLLQQELTAAEQ 286
Cdd:TIGR02168  323 AQLEELESK--LDELAEELAELEEKLEELKEELESLEAElEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNN 400

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  287 RNQILSQQLQQMEAEHNTLRNTVETEREE-SKILLEKMELEVAERKLSFHNLQEEMHHLLEQFEQAGQAQAELESRYSAL 365
Cdd:TIGR02168  401 EIERLEARLERLEDRRERLQQEIEELLKKlEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAA 480

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  366 EQKHKAEMEEKTShILSLQKTGQELQSACDALKDQNSKLLQDKN------------EQAVQSA--QTIQQLEDQLQQKSK 431
Cdd:TIGR02168  481 ERELAQLQARLDS-LERLQENLEGFSEGVKALLKNQSGLSGILGvlselisvdegyEAAIEAAlgGRLQAVVVENLNAAK 559

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  432 EISQFLnrlplQQHETASQTSFPdvynegtqaVTEENIASLQKRVVELENEKGALLLSSIELEELKAENEKLSSQI---- 507
Cdd:TIGR02168  560 KAIAFL-----KQNELGRVTFLP---------LDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLlggv 625

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  508 ----TLLEAQNRTGEADREVSEISIV-DIANKRSSSAEESGQDVLeNTFSQKhKELSVLLLEMKEAQEEIAFLKLQLQgk 582
Cdd:TIGR02168  626 lvvdDLDNALELAKKLRPGYRIVTLDgDLVRPGGVITGGSAKTNS-SILERR-REIEELEEKIEELEEKIAELEKALA-- 701

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  583 RAEEADHEVLDQKEMKQMEGEGIapikmkvfledtgqdfplmpNEESSLPAVEKEQASTEHQSRTSEEISLndagvelks 662
Cdd:TIGR02168  702 ELRKELEELEEELEQLRKELEEL--------------------SRQISALRKDLARLEAEVEQLEERIAQL--------- 752

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  663 tkqdgdkslsavpdigqchQDELERLKSQILELELNFHKAQEiyekNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALS 742
Cdd:TIGR02168  753 -------------------SKELTELEAEIEELEERLEEAEE----ELAEAEAEIEELEAQIEQLKEELKALREALDELR 809

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  743 EErdqlLSQVKELsmVTELRAQVKQLEMNLAEAERQ-RRLDYESQTahdnlLTEQIHSLSIEAKSKDVKIEVLQNELDDV 821
Cdd:TIGR02168  810 AE----LTLLNEE--AANLRERLESLERRIAATERRlEDLEEQIEE-----LSEDIESLAAEIEELEELIEELESELEAL 878

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  822 QLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKR----DVETLQQTIEE 897
Cdd:TIGR02168  879 LNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQErlseEYSLTLEEAEA 958

                          890       900
                   ....*....|....*....|....*..
gi 1034632655  898 KDQQVTEISFSMTEKMVQLNEEKFSLG 924
Cdd:TIGR02168  959 LENKIEDDEEEARRRLKRLENKIKELG 985
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1494-2087 1.33e-10

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 67.40  E-value: 1.33e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1494 ALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMD---RSLLENQSLSSSCES 1570
Cdd:PRK03918   163 AYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEkleKEVKELEELKEEIEE 242

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1571 LKLALEGLTEDKEKL---VKEIESLKSSKIAESTEWQEKHKELQ------KEYEILLQSYENVSNEAERIQHVVEAVRQE 1641
Cdd:PRK03918   243 LEKELESLEGSKRKLeekIRELEERIEELKKEIEELEEKVKELKelkekaEEYIKLSEFYEEYLDELREIEKRLSRLEEE 322

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1642 KQELYGKLRstEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHPagdtakecmetllssna 1721
Cdd:PRK03918   323 INGIEERIK--ELEEKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTG----------------- 383

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1722 smkEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEgnvSKQANLEATEKHDNQTNV-----TEEGTQSIPGET 1796
Cdd:PRK03918   384 ---LTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIK---ELKKAIEELKKAKGKCPVcgrelTEEHRKELLEEY 457

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1797 EEQDSLSMSTRPTCSESVPSAKSANPAVSKDFSSHDEINNYLQQIDQLKEriagLEEE-KQKNKEFSQTLENEKNTLLSQ 1875
Cdd:PRK03918   458 TAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQLKE----LEEKlKKYNLEELEKKAEEYEKLKEK 533

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1876 ISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAEEEKDDLEERLMNQLAELNGSIGNYcqdvtdaqiknELLES 1955
Cdd:PRK03918   534 LIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKEL-----------EPFYN 602

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1956 EMKNLKKCVSELEEEKQQLVKEKTKVESEIrkEYLEKIQGAQKEPgnkshAKELQELLKE-KQQEVKQLQKDCIRYQEKI 2034
Cdd:PRK03918   603 EYLELKDAEKELEREEKELKKLEEELDKAF--EELAETEKRLEEL-----RKELEELEKKySEEEYEELREEYLELSREL 675

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1034632655 2035 SALERTVKALEFVQTESQKDLEITKENLaqavEHRKKAQAELASFKVLLDDTQ 2087
Cdd:PRK03918   676 AGLRAELEELEKRREEIKKTLEKLKEEL----EEREKAKKELEKLEKALERVE 724
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 682-1255 1.73e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 67.27  E-value: 1.73e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  682 QDELERLKSQILELElnfhKAQEIYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLSQVKelsmvtEL 761
Cdd:COG1196    238 EAELEELEAELEELE----AELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIA------RL 307

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  762 RAQVKQLEMNLAEAERQRrldyESQTAHDNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQN 841
Cdd:COG1196    308 EERRRELEERLEELEEEL----AELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEE 383

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  842 KESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEIsfsmTEKMVQLNEEKF 921
Cdd:COG1196    384 LAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEA----AEEEAELEEEEE 459

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  922 SLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEMSPAGQISKEelqhefdllkKENEQRKRKLQAALInr 1001
Cdd:COG1196    460 ALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKA----------ALLLAGLRGLAGAVA-- 527

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1002 kELLQRVSRLEEELANLKDESKKEIPLSETERGE--VEEDKENKEysekcvtskcqeieiyLKQTISEKEVELQHIRKDL 1079
Cdd:COG1196    528 -VLIGVEAAYEAALEAALAAALQNIVVEDDEVAAaaIEYLKAAKA----------------GRATFLPLDKIRARAALAA 590

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1080 EEKLAAEEQFQALVKQMNQTLQDK-TNQIDLLQAEISENQAIIQKLITSNTDASDGDSVALVKETVVISPPCTGSSEHWK 1158
Cdd:COG1196    591 ALARGAIGAAVDLVASDLREADARyYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRREL 670

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1159 PELEEKILALEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQ 1238
Cdd:COG1196    671 LAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEE 750

                          570
                   ....*....|....*..
gi 1034632655 1239 VRESIDGKLPSTDQQES 1255
Cdd:COG1196    751 EALEELPEPPDLEELER 767
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1841-2623 3.53e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 66.24  E-value: 3.53e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1841 IDQLKERIAGLEEEKQKNKEFSQTLE-----------NEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTK 1909
Cdd:TIGR02169  193 IDEKRQQLERLRREREKAERYQALLKekreyegyellKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQ 272

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1910 LKETAEEEKDDLEERLMNQLaelngsignycqdvtdaQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEy 1989
Cdd:TIGR02169  273 LLEELNKKIKDLGEEEQLRV-----------------KEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKL- 334

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1990 lekiqgaqkepgnKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEfvqtesqKDLEITKENLAQAVEHR 2069
Cdd:TIGR02169  335 -------------LAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVD-------KEFAETRDELKDYREKL 394

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2070 KKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKsQMKQKDEDLERRLEQAEEKhlkeKKNMQEKLDALRR 2149
Cdd:TIGR02169  395 EKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKIN-ELEEEKEDKALEIKKQEWK----LEQLAADLSKYEQ 469

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2150 EKVHLEETIGEIQVTLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRV---IDEAKKWERKFSDAIQS------ 2220
Cdd:TIGR02169  470 ELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVhgtVAQLGSVGERYATAIEVaagnrl 549

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2221 -----------KEEEIRLKEDNCS--------VLKDQLRQMSIHMEE--LKINISRLEHDKQ-------------IWESK 2266
Cdd:TIGR02169  550 nnvvveddavaKEAIELLKRRKAGratflplnKMRDERRDLSILSEDgvIGFAVDLVEFDPKyepafkyvfgdtlVVEDI 629

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2267 AQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEA 2346
Cdd:TIGR02169  630 EAARRLMGKYRMVTLEGELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQ 709

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2347 DIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKIisllsgkeEAIQVAIAELRQqhdkEIKELENLLSQEEEenivl 2426
Cdd:TIGR02169  710 ELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDL--------SSLEQEIENVKS----ELKELEARIEELEE----- 772

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2427 eeenkkavdKTNQLMETLKTIKKENIQQkaQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSIILEKDQL---IQEAAAE 2503
Cdd:TIGR02169  773 ---------DLHKLEEALNDLEARLSHS--RIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLekeIQELQEQ 841

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2504 NNKLKEEIRGLRSHMDDLNSENAKLDAELiqyredlnqvitikdsqqkqllevqlqqnKELENKYAKLEEKLKESEEANE 2583
Cdd:TIGR02169  842 RIDLKEQIKSIEKEIENLNGKKEELEEEL-----------------------------EELEAALRDLESRLGDLKKERD 892

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|
gi 1034632655 2584 DLRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTALQEE 2623
Cdd:TIGR02169  893 ELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEE 932
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 634-1229 4.77e-10

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 65.91  E-value: 4.77e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  634 VEKEQASTEHQSRTSEEISLNDAGVELKSTKQDGDKSLSAVPDIGQCHQDELERLKSQILELELNFHKAQEIYEKNLDEK 713
Cdd:pfam15921  243 VEDQLEALKSESQNKIELLLQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQARNQNSMYMRQLSDL 322

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  714 AKEISNLNQLIEEFKKNADNNssaftaLSEERDQLLSQVKELSMVTELRAQVKQLEMNLAEAERQRRLDYESQTAHDNLL 793
Cdd:pfam15921  323 ESTVSQLRSELREAKRMYEDK------IEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELSLE 396

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  794 TEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVL-------EGAERVRHISSKVEELSQA 866
Cdd:pfam15921  397 KEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMaaiqgknESLEKVSSLTAQLESTKEM 476

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  867 LSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTeKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKE 946
Cdd:pfam15921  477 LRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEIT-KLRSRVDLKLQELQHLKNEGDHLRNVQTECEALKL 555

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  947 QVEEDNEVSSGLKQNYDEMSP----------AGQISKEELQ----------HEFDLLKKENEQRKRKLQAAL----INRK 1002
Cdd:pfam15921  556 QMAEKDKVIEILRQQIENMTQlvgqhgrtagAMQVEKAQLEkeindrrlelQEFKILKDKKDAKIRELEARVsdleLEKV 635

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1003 ELLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIY---LKQTISEKEVELQHIRKDL 1079
Cdd:pfam15921  636 KLVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTtnkLKMQLKSAQSELEQTRNTL 715

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1080 EEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEisenqaiIQKLITSNTDASDGDSVALVKETVVISPPCTGSSEHWKP 1159
Cdd:pfam15921  716 KSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSK-------IQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKM 788

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1160 ELEEKILALEkekeqlQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIG 1229
Cdd:pfam15921  789 AGELEVLRSQ------ERRLKEKVANMEVALDKASLQFAECQDIIQRQEQESVRLKLQHTLDVKELQGPG 852
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 201-755 7.86e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 64.96  E-value: 7.86e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  201 TLQAQLSQTQAEQAA---QVVREKDARFETQVRLHEDELLQLVTQADVE----TEMQQKLRVLQRKLEEHEESLVGRAQV 273
Cdd:COG1196    217 ELKEELKELEAELLLlklRELEAELEELEAELEELEAELEELEAELAELeaelEELRLELEELELELEEAQAEEYELLAE 296

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  274 VDLLQQELTAAEQRNQILSQQLQQMEAEHNTLRNTVETEREESKILLEKMELEVAERKLSFHNLQEEMHHLLEQFEQAGQ 353
Cdd:COG1196    297 LARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAE 376

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  354 AQAELESRYSALEQKhKAEMEEKTSHILSLQKTGQELQSACDALKDQNSKLLQDKNEQAVQSAQTIQQLEDQLQQKSKEI 433
Cdd:COG1196    377 AEEELEELAEELLEA-LRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELE 455

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  434 SQFLNrlpLQQHETASQTSFPDVYNEGTQAVTEENIASLQKRVVELENEKGALLLSSIELEELKAENEKLSSQI-TLLEA 512
Cdd:COG1196    456 EEEEA---LLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVaVLIGV 532

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  513 QNRTGEADREVSEISIVDIANKRSSSAEESGQDVLEN-----TFSQKHK-------ELSVLLLEMKEAQEEIAFLKLQLQ 580
Cdd:COG1196    533 EAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAkagraTFLPLDKiraraalAAALARGAIGAAVDLVASDLREAD 612

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  581 GKRAEEADHEVLDQKEMKQMEGEGIAPIKMKVFLEDTGQDFPLMPNEESSLPAVEKEQASTEHQSRTSEEISLNDAGVEL 660
Cdd:COG1196    613 ARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEE 692

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  661 KSTKQDgdkslsavpdigqchQDELERLKSQILELELNFHKAQEIYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTA 740
Cdd:COG1196    693 LELEEA---------------LLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELP 757

                          570
                   ....*....|....*
gi 1034632655  741 LSEERDQLLSQVKEL 755
Cdd:COG1196    758 EPPDLEELERELERL 772
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 755-1486 8.28e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 65.09  E-value: 8.28e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  755 LSMVTELRAQVKQLEMNLAEAER-----QRRLDYESQTAHDNLLTEQIHSLSIEAKSKDVKIEVlQNELDDVQLQFSEQS 829
Cdd:TIGR02169  229 LKEKEALERQKEAIERQLASLEEeleklTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRV-KEKIGELEAEIASLE 307

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  830 TLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEisfsM 909
Cdd:TIGR02169  308 RSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAE----T 383

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  910 TEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQnydemspagqiSKEELQHEFDLLKKENEQ 989
Cdd:TIGR02169  384 RDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEA-----------KINELEEEKEDKALEIKK 452

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  990 RKRKLQAALINRKELLQRVSRLEEELANLKDE---SKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIYLKQTIS 1066
Cdd:TIGR02169  453 QEWKLEQLAADLSKYEQELYDLKEEYDRVEKElskLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGS 532

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1067 EKE-----VE------LQHIRKDLEEKLAAEEQFQALVK----------QMNQTLQDKT---------NQIDLL----QA 1112
Cdd:TIGR02169  533 VGEryataIEvaagnrLNNVVVEDDAVAKEAIELLKRRKagratflplnKMRDERRDLSilsedgvigFAVDLVefdpKY 612

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1113 EISENQAIIQKLITSNTDASD--GDSVALVK---ETVVISPPCTGSS------EHWKPELEEKILALEKEKEQLQKKLQE 1181
Cdd:TIGR02169  613 EPAFKYVFGDTLVVEDIEAARrlMGKYRMVTlegELFEKSGAMTGGSraprggILFSRSEPAELQRLRERLEGLKRELSS 692

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1182 ALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVRESIDGKlpsTDQQESCSSTPG 1261
Cdd:TIGR02169  693 LQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVK---SELKELEARIEE 769

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1262 LEEPLFKATEQhhtqpvlesnlcpdwpshSEDASALQGGTSVAQIKAQLKEIEAEKVELELKVSSTTSELTKKSEEVFQL 1341
Cdd:TIGR02169  770 LEEDLHKLEEA------------------LNDLEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYL 831

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1342 QEqinkqglEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLE-HLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAA 1420
Cdd:TIGR02169  832 EK-------EIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEeELEELEAALRDLESRLGDLKKERDELEAQLRELERK 904

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1034632655 1421 LTKIQTEIIEQEDLIKALHTQLEMQAkehdERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQA 1486
Cdd:TIGR02169  905 IEELEAQIEKKRKRLSELKAKLEALE----EELSEIEDPKGEDEEIPEEELSLEDVQAELQRVEEE 966
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1838-2338 9.98e-10

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 64.70  E-value: 9.98e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1838 LQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMNLLnQQIQEELSRVTKLKETAEEE 1917
Cdd:PRK03918   230 VKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKEL-KEKAEEYIKLSEFYEEYLDE 308

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1918 KDDLEERLMNQLAELNGsIGNYCQDVTDAQIKNELLESEMKNLKKCVSELE------EEKQQLVKEKTKVESEIRKEYLE 1991
Cdd:PRK03918   309 LREIEKRLSRLEEEING-IEERIKELEEKEERLEELKKKLKELEKRLEELEerhelyEEAKAKKEELERLKKRLTGLTPE 387

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1992 KIQGAQKEPGNKShaKELQELLKEKQQEVKQLQKDCIRYQEKISALER------------TVKALEFVQTESQKDLEITK 2059
Cdd:PRK03918   388 KLEKELEELEKAK--EEIEEEISKITARIGELKKEIKELKKAIEELKKakgkcpvcgrelTEEHRKELLEEYTAELKRIE 465

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2060 ENLAQAVEHRKKAQAELASFKVLLddtqsEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKN 2139
Cdd:PRK03918   466 KELKEIEEKERKLRKELRELEKVL-----KKESELIKLKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGE 540

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2140 MQ------EKLDALRREKVHLEETIGEIQVTLNKKDKEVQQL----QENLDSTVTQLAAFTKSMSSLQDDRDRVIDEAKK 2209
Cdd:PRK03918   541 IKslkkelEKLEELKKKLAELEKKLDELEEELAELLKELEELgfesVEELEERLKELEPFYNEYLELKDAEKELEREEKE 620

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2210 werkfsdaIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELKINISRLEHdkqiweskaqtevqlqqkvcdtlqgenkell 2289
Cdd:PRK03918   621 --------LKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEY------------------------------- 661

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....*....
gi 1034632655 2290 sqlEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLE 2338
Cdd:PRK03918   662 ---EELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEERE 707
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2219-2770 1.40e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 64.19  E-value: 1.40e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2219 QSKEEEIRLKEDNCSVLKDQLRQMSIhmEELKINISRLEHDKQiwesKAQTEVQLQQKVCDTLQGENKELLSQLEETRHL 2298
Cdd:COG1196    216 RELKEELKELEAELLLLKLRELEAEL--EELEAELEELEAELE----ELEAELAELEAELEELRLELEELELELEEAQAE 289

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2299 YHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEINM 2378
Cdd:COG1196    290 EYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLE 369

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2379 KEQKIISLLSGKEEA-------------IQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLK 2445
Cdd:COG1196    370 AEAELAEAEEELEELaeellealraaaeLAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAE 449

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2446 TIKK---ENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSII-LEKDQLIQEAAAENNKLKEEIRGLRSHMDDL 2521
Cdd:COG1196    450 EEAEleeEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLeAEADYEGFLEGVKAALLLAGLRGLAGAVAVL 529

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2522 NSENAKLDAELIQYREDLNQVITIKDSQQ-KQLLEVQLQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLS 2600
Cdd:COG1196    530 IGVEAAYEAALEAALAAALQNIVVEDDEVaAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLR 609

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2601 KEIESLKVSISQLTRQVTALQEEGTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELVCVQKEAAKKVGEIEDKLK 2680
Cdd:COG1196    610 EADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLA 689

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2681 KELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEELDELKRKY 2760
Cdd:COG1196    690 EEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELEREL 769

                          570
                   ....*....|
gi 1034632655 2761 DASLKELAQL 2770
Cdd:COG1196    770 ERLEREIEAL 779
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2050-2661 1.86e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 63.80  E-value: 1.86e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2050 ESQKDLEITKENLAQA----VEHRK-----KAQAELAsfkvllddtqsEAARVLADNLKLKK-ELQSNKESVKSQMKQKD 2119
Cdd:COG1196    176 EAERKLEATEENLERLedilGELERqleplERQAEKA-----------ERYRELKEELKELEaELLLLKLRELEAELEEL 244

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2120 EDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQENLDSTVTQLAAftksmssLQDD 2199
Cdd:COG1196    245 EAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRE-------LEER 317

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2200 RDRVIDEAKKWERKFSDAIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQTEVQLQQKVCD 2279
Cdd:COG1196    318 LEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAE 397

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2280 TLQgENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLE 2359
Cdd:COG1196    398 LAA-QLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLE 476

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2360 TDLQASRELTSRLHEEINMKEQkIISLLSGKEEAIQvAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQ 2439
Cdd:COG1196    477 AALAELLEELAEAAARLLLLLE-AEADYEGFLEGVK-AALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVE 554

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2440 LMETLKTIKKENIQQKAQLDSF-----VKSMSSLQNDRDRIVGDYQQLEERHLSIILE-KDQLIQEAAAENNKLKEEIRG 2513
Cdd:COG1196    555 DDEVAAAAIEYLKAAKAGRATFlpldkIRARAALAAALARGAIGAAVDLVASDLREADaRYYVLGDTLLGRTLVAARLEA 634

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2514 LRSHMDDLNSENAKLDAELIQyREDLNQVITIKDSQQKQLLEVQLQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQ 2593
Cdd:COG1196    635 ALRRAVTLAGRLREVTLEGEG-GSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAE 713

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1034632655 2594 EEKQDLSKEIESLKVSISQLTRQVTALQEEGTLGLYHAQLKVKEEEVHRlsalfSSSQKRIAELEEEL 2661
Cdd:COG1196    714 EERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDL-----EELERELERLEREI 776
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1832-2616 2.36e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 63.55  E-value: 2.36e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1832 DEINNYLQQIDQLKERIAGLEEEKQKN-KEFSQTLENEKNTLLSQISTKDGELKMLQEEVTK-----------MNLLNQQ 1899
Cdd:TIGR02169  265 KRLEEIEQLLEELNKKIKDLGEEEQLRvKEKIGELEAEIASLERSIAEKERELEDAEERLAKleaeidkllaeIEELERE 344

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1900 IQEELSRVTKLKETAEEEKDDLEErLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKT 1979
Cdd:TIGR02169  345 IEEERKRRDKLTEEYAELKEELED-LRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELA 423

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1980 KVESEIrkeylEKIQGAQKEpgNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEItK 2059
Cdd:TIGR02169  424 DLNAAI-----AGIEAKINE--LEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAE-A 495

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2060 ENLAQAVEHRkkaQAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQ----KDEDL---------ERRL 2126
Cdd:TIGR02169  496 EAQARASEER---VRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEVAAGNRLNnvvvEDDAVakeaiellkRRKA 572

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2127 EQAEEKHLKEKKNMQEKLDALRREKVHleetigEIQVTLNKKDKEVQQ----------LQENLDSTVTQLAAFtkSMSSL 2196
Cdd:TIGR02169  573 GRATFLPLNKMRDERRDLSILSEDGVI------GFAVDLVEFDPKYEPafkyvfgdtlVVEDIEAARRLMGKY--RMVTL 644

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2197 QDD----RDRVIDEAKKWERKFSDAIQSKEEEIRLKEDncsvLKDQLRQMSIHMEELKiNISRLEHDKQIWESKAQTEVQ 2272
Cdd:TIGR02169  645 EGElfekSGAMTGGSRAPRGGILFSRSEPAELQRLRER----LEGLKRELSSLQSELR-RIENRLDELSQELSDASRKIG 719

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2273 LQQKVCDTLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEadIQNSK 2352
Cdd:TIGR02169  720 EIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSR--IPEIQ 797

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2353 FSYEQLETDLQASRELTSRLHEEINMKEQKiisllsgkeeaiqvaiaelRQQHDKEIKELENLLsqeeEENIVLEEENKK 2432
Cdd:TIGR02169  798 AELSKLEEEVSRIEARLREIEQKLNRLTLE-------------------KEYLEKEIQELQEQR----IDLKEQIKSIEK 854

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2433 AVDKTNQLMETLKTIKKENIQQKAQLDsfvKSMSSLQNDRDRIVGDYQQLEERhlsiilekdqlIQEAAAENNKLKEEIR 2512
Cdd:TIGR02169  855 EIENLNGKKEELEEELEELEAALRDLE---SRLGDLKKERDELEAQLRELERK-----------IEELEAQIEKKRKRLS 920

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2513 GLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDSQQK-QLLEVQLQQNKELENKYAKLEeklkeseeanEDLRRSFNA 2591
Cdd:TIGR02169  921 ELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDVQAElQRVEEEIRALEPVNMLAIQEY----------EEVLKRLDE 990

                          810       820
                   ....*....|....*....|....*
gi 1034632655 2592 LQEEKQDLSKEIESLKVSISQLTRQ 2616
Cdd:TIGR02169  991 LKEKRAKLEEERKAILERIEEYEKK 1015
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1626-2401 3.74e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 62.78  E-value: 3.74e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1626 NEAERIQHVVEAVRQ-EKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHP 1704
Cdd:TIGR02169  208 EKAERYQALLKEKREyEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEE 287

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1705 AGDTAKECMETLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQANLEATEKHDnqtnv 1784
Cdd:TIGR02169  288 EQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAEL----- 362

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1785 tEEGTQSIPGETEEQDSLSMSTRptcsesvpsaksanpavskdfsshDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQT 1864
Cdd:TIGR02169  363 -KEELEDLRAELEEVDKEFAETR------------------------DELKDYREKLEKLKREINELKRELDRLQEELQR 417

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1865 LENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAEEEKDDLEERLmnqlaelngsignycqdvt 1944
Cdd:TIGR02169  418 LSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEY------------------- 478

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1945 daqiknELLESEMKNLKKCVSELEEEKQQLVKEKT--KVESEIRKEYLEKIQGAQKEPG--NKSHAKELQELLKEKQQEV 2020
Cdd:TIGR02169  479 ------DRVEKELSKLQRELAEAEAQARASEERVRggRAVEEVLKASIQGVHGTVAQLGsvGERYATAIEVAAGNRLNNV 552

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2021 ----KQLQKDCIRYQEKISALERTVKALEFVQTEsQKDLEITKEN-----LAQAVEHRKKAQaelASFKVLLDDT----Q 2087
Cdd:TIGR02169  553 vvedDAVAKEAIELLKRRKAGRATFLPLNKMRDE-RRDLSILSEDgvigfAVDLVEFDPKYE---PAFKYVFGDTlvveD 628

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2088 SEAARVLADNLKL--------------------KKELQSNKESVKSQMKQKDEDLErRLEQAEEKHLKEKKNMQEKLDAL 2147
Cdd:TIGR02169  629 IEAARRLMGKYRMvtlegelfeksgamtggsraPRGGILFSRSEPAELQRLRERLE-GLKRELSSLQSELRRIENRLDEL 707

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2148 RREKVHLEETIGEIQvtlnkkdKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVIDEAKKWERKfsdaIQSKEEEIRL 2227
Cdd:TIGR02169  708 SQELSDASRKIGEIE-------KEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEAR----IEELEEDLHK 776

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2228 KEDNCSVLKDQLRQMSI-----HMEELKINISRLE----HDKQIWESKAQTEVQLQQKVcDTLQGENKELLSQLEETRHL 2298
Cdd:TIGR02169  777 LEEALNDLEARLSHSRIpeiqaELSKLEEEVSRIEarlrEIEQKLNRLTLEKEYLEKEI-QELQEQRIDLKEQIKSIEKE 855

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2299 YHSSQNELAKLESELKSLKDQLTDLSnslekckEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEINM 2378
Cdd:TIGR02169  856 IENLNGKKEELEEELEELEAALRDLE-------SRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEA 928

                          810       820
                   ....*....|....*....|...
gi 1034632655 2379 KEQKIISLLSGKEEAIQVAIAEL 2401
Cdd:TIGR02169  929 LEEELSEIEDPKGEDEEIPEEEL 951
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 48-607 4.48e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 62.65  E-value: 4.48e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655   48 EDVQERLAyaeqlvvELKDIIRQKDVQLqqkdEALQEERKAADNKIKKLKLHAKAKLTSLNKYIEEMKAQGGTVLPTEPQ 127
Cdd:COG1196    182 EATEENLE-------RLEDILGELERQL----EPLERQAEKAERYRELKEELKELEAELLLLKLRELEAELEELEAELEE 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  128 SEEQLSKHDKSSTEEEMEIEKIKHKLQEKEELISTLQAQLTQAQAEQPAQSST------EMEEFVMMKQQLQEKEEFIST 201
Cdd:COG1196    251 LEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDiarleeRRRELEERLEELEEELAELEE 330

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  202 LQAQLSQTQAEQAAQVVREKDARFETQVRLHEDELLQLVTQADVETEMQQKLRVLQRKLEEHEESLVGRAQVVDLLQQEL 281
Cdd:COG1196    331 ELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEE 410

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  282 TAAEQRNQILSQQLQQMEAEHNTLRNTVETEREESKILLEKMELEVAERKL--SFHNLQEEMHHLLEQFEQAGQAQAELE 359
Cdd:COG1196    411 ALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALleLLAELLEEAALLEAALAELLEELAEAA 490

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  360 SRYSALEQKHKAEMEEKTSHILSLQKTGQELQSACDALKDQNSKLLQDKNEQA---------VQSAQTIQQLEDQLQQKS 430
Cdd:COG1196    491 ARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAAlaaalqnivVEDDEVAAAAIEYLKAAK 570

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  431 KEISQFLNRLPLQQHETASQTSFPDVYNEGTQAVTEENIASLQKRVVELENEKGALLLSSIELEELK--AENEKLSSQIT 508
Cdd:COG1196    571 AGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRraVTLAGRLREVT 650

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  509 LLEAQNRTGEADREVSEISIVDIANKRSSSAEESGQDVLENTFSQKHKELSVLLLEMKEAQEEIAFLKLQLQGKRAEEAD 588
Cdd:COG1196    651 LEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQL 730

                          570
                   ....*....|....*....
gi 1034632655  589 HEVLDQKEMKQMEGEGIAP 607
Cdd:COG1196    731 EAEREELLEELLEEEELLE 749
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 554-1244 4.72e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 62.77  E-value: 4.72e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  554 KHKELSVLLLEMKEAQEEIAFLKLQLqgkraEEADHEVLDQKEMKQMEGEGIAPIKMKVFledtgqdfplmpneesslpa 633
Cdd:TIGR02168  223 RELELALLVLRLEELREELEELQEEL-----KEAEEELEELTAELQELEEKLEELRLEVS-------------------- 277

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  634 vEKEQASTEHQSR---TSEEISlndagvELKSTKQDGDKSLSAVPDIGQCHQDELERLKSQILELELNFHKAQEIYE--- 707
Cdd:TIGR02168  278 -ELEEEIEELQKElyaLANEIS------RLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEelk 350

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  708 KNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLSQVKEL-SMVTELRAQVKQLEmnlaeaERQRRLDYESQ 786
Cdd:TIGR02168  351 EELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLnNEIERLEARLERLE------DRRERLQQEIE 424

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  787 TAHDNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQ- 865
Cdd:TIGR02168  425 ELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGf 504

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  866 -----ALSQKELEITKMDQLLLEK-------KRDVET-----LQQTIEEKDQQVTEISFSMTEK-----------MVQLN 917
Cdd:TIGR02168  505 segvkALLKNQSGLSGILGVLSELisvdegyEAAIEAalggrLQAVVVENLNAAKKAIAFLKQNelgrvtflpldSIKGT 584

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  918 EEKFSLGVEIKTLKEQLNLLSRAEEAKK----------------EQVEEDNEVSSGLKQNY-------DEMSPAGQISKE 974
Cdd:TIGR02168  585 EIQGNDREILKNIEGFLGVAKDLVKFDPklrkalsyllggvlvvDDLDNALELAKKLRPGYrivtldgDLVRPGGVITGG 664

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  975 ELQHEFDLLK-----KENEQRKRKLQAALINRKELLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKENKEYSEKC 1049
Cdd:TIGR02168  665 SAKTNSSILErrreiEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQ 744

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1050 VTSKCQEIEIYLKQTISEKEVELQHIRKDLEEKLAAE---EQFQALVKQMNQTLQDKTNQIDLLQAEISENQAIIQKLit 1126
Cdd:TIGR02168  745 LEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEaeiEELEAQIEQLKEELKALREALDELRAELTLLNEEAANL-- 822

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1127 SNTDASDGDSVALVKETVVISPPCTGSSEHWKPELEEKILALEKEKEQLQKKLQEALTSRKAI---LKKAQEKERHLREE 1203
Cdd:TIGR02168  823 RERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLeeaLALLRSELEELSEE 902

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|.
gi 1034632655 1204 LKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVRESID 1244
Cdd:TIGR02168  903 LRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQE 943
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 2169-2922 4.74e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 62.78  E-value: 4.74e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2169 DKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVIDEAKKWERkfSDAIQSKEEEIRLKEdncsvLKDQLRQMSIHMEE 2248
Cdd:TIGR02169  169 DRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAER--YQALLKEKREYEGYE-----LLKEKEALERQKEA 241

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2249 LKINISRLEhdkqiwESKAQTEVQLQQKVCDTlqGENKELLSQLEEtrHLYHSSQNELAKLESELKSLKDQLTDLSNSLE 2328
Cdd:TIGR02169  242 IERQLASLE------EELEKLTEEISELEKRL--EEIEQLLEELNK--KIKDLGEEEQLRVKEKIGELEAEIASLERSIA 311

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2329 KCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKIISLLSgKEEAIQVAIAELRQQHDKE 2408
Cdd:TIGR02169  312 EKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRA-ELEEVDKEFAETRDELKDY 390

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2409 IKELENL-----------------LSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQND 2471
Cdd:TIGR02169  391 REKLEKLkreinelkreldrlqeeLQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQE 470

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2472 RDRIVGDYQQLEERhlsiILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENA---KLDAELIQYRED---------- 2538
Cdd:TIGR02169  471 LYDLKEEYDRVEKE----LSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQgvhGTVAQLGSVGERyataievaag 546

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2539 --LNQVITIKDSQQKQLLEVqLQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSKEIESLKVSISQLTRQ 2616
Cdd:TIGR02169  547 nrLNNVVVEDDAVAKEAIEL-LKRRKAGRATFLPLNKMRDERRDLSILSEDGVIGFAVDLVEFDPKYEPAFKYVFGDTLV 625

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2617 VTALQEEGTLGLYHAQLKVKEEEVHRLSALFSSSqkRIAELEEELVCVQKEAAKKVGEIEDKLKKELKHLHHDAGIMRNE 2696
Cdd:TIGR02169  626 VEDIEAARRLMGKYRMVTLEGELFEKSGAMTGGS--RAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENR 703

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2697 TETAEERVAELARDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEELDELKrkydaslKELAQLKEQglL 2776
Cdd:TIGR02169  704 LDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELE-------ARIEELEED--L 774

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2777 NRERDALLSETAFSMNSTEENSLSHLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKFRK 2856
Cdd:TIGR02169  775 HKLEEALNDLEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEK 854

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2857 SEEG----KQRSAAQPSTSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELHPLKAQLQE 2922
Cdd:TIGR02169  855 EIENlngkKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKA 924
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 1831-2544 8.74e-09

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 61.99  E-value: 8.74e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1831 HDEINNYLQQIDQL-KERIAGLEEEKQKNKEFSQTLENEKNTLLSQIS----TKDGELKMlQEEVTKMN----LLNQQIQ 1901
Cdd:TIGR01612 1050 HTSIYNIIDEIEKEiGKNIELLNKEILEEAEINITNFNEIKEKLKHYNfddfGKEENIKY-ADEINKIKddikNLDQKID 1128

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1902 EELSRVTKLKETAEEEKDDLEERLmnqlaelngsigNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEK------QQLV 1975
Cdd:TIGR01612 1129 HHIKALEEIKKKSENYIDEIKAQI------------NDLEDVADKAISNDDPEEIEKKIENIVTKIDKKKniydeiKKLL 1196

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1976 KEKTKVESEirKEYLEKIQGAqkepgNKSHAKELQELLKEKQQEVKQLQKDCIRYQEK-ISALERTVKALEFVQTESQKD 2054
Cdd:TIGR01612 1197 NEIAEIEKD--KTSLEEVKGI-----NLSYGKNLGKLFLEKIDEEKKKSEHMIKAMEAyIEDLDEIKEKSPEIENEMGIE 1269

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2055 LEITKENLAQAVEHRKKAQAELASFK--VLLDDTQSEAARVLADNLK------LKKELQSNKesvkSQMKQKDEDLERRL 2126
Cdd:TIGR01612 1270 MDIKAEMETFNISHDDDKDHHIISKKhdENISDIREKSLKIIEDFSEesdindIKKELQKNL----LDAQKHNSDINLYL 1345

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2127 EQ-AEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQENLDstvtqLAAFTKSMSSLQDDRDrvID 2205
Cdd:TIGR01612 1346 NEiANIYNILKLNKIKKIIDEVKEYTKEIEENNKNIKDELDKSEKLIKKIKDDIN-----LEECKSKIESTLDDKD--ID 1418

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2206 EAKKWERKFSDAIQSKEEEI-----RLKEDNCSVLK-----DQLRQMSIHMEELKINISRLEHDKQIWESKAQTEvqlQQ 2275
Cdd:TIGR01612 1419 ECIKKIKELKNHILSEESNIdtyfkNADENNENVLLlfkniEMADNKSQHILKIKKDNATNDHDFNINELKEHID---KS 1495

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2276 KVCDTLQGENKEllsQLEETRHLYHSSQNELAKL-----ESELKSLKDQLTDLSNSL-EKCKEQKGNL---EGIIRQQEA 2346
Cdd:TIGR01612 1496 KGCKDEADKNAK---AIEKNKELFEQYKKDVTELlnkysALAIKNKFAKTKKDSEIIiKEIKDAHKKFileAEKSEQKIK 1572

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2347 DIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKIISllsgkeeaiqvaIAELRQQHDKEIKELENLLSQEEE----E 2422
Cdd:TIGR01612 1573 EIKKEKFRIEDDAAKNDKSNKAAIDIQLSLENFENKFLK------------ISDIKKKINDCLKETESIEKKISSfsidS 1640

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2423 NIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQqleerhLSIIlekDQLIQEAAA 2502
Cdd:TIGR01612 1641 QDTELKENGDNLNSLQEFLESLKDQKKNIEDKKKELDELDSEIEKIEIDVDQHKKNYE------IGII---EKIKEIAIA 1711

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|..
gi 1034632655 2503 ENNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVIT 2544
Cdd:TIGR01612 1712 NKEEIESIKELIEPTIENLISSFNTNDLEGIDPNEKLEEYNT 1753
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 2303-2772 1.11e-08

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 61.19  E-value: 1.11e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2303 QNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHE--EINMKE 2380
Cdd:TIGR04523  151 EKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLSNLKKKIQKNKSLESQISElkKQNNQL 230

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2381 QKIISLLSGKEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDS 2460
Cdd:TIGR04523  231 KDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEQDWNK 310

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2461 FVKSmsSLQNDRDRIVGDYQQLEERHLSIilekdqliqeaaaenNKLKEEIRGLRSHMDDLNSENAKLDAELiqyREDLN 2540
Cdd:TIGR04523  311 ELKS--ELKNQEKKLEEIQNQISQNNKII---------------SQLNEQISQLKKELTNSESENSEKQREL---EEKQN 370

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2541 QVITIKDSQQKQLlevqlQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTAL 2620
Cdd:TIGR04523  371 EIEKLKKENQSYK-----QEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDL 445

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2621 QEEGTlglyhaqlkVKEEEVHRLSALFSSSQKRIAELEEELVCVQKEAAKKVGEIEDKlKKELKHLHHDAGIMRNETETA 2700
Cdd:TIGR04523  446 TNQDS---------VKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSK-EKELKKLNEEKKELEEKVKDL 515

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1034632655 2701 EERVAELARDLVEMEQKLLMVTKENKGLTAQIQS--FGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKE 2772
Cdd:TIGR04523  516 TKKISSLKEKIEKLESEKKEKESKISDLEDELNKddFELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQE 589
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1841-2156 1.15e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 61.11  E-value: 1.15e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1841 IDQLKERIAGLEEEKQKNKEFsQTLENEKNTL-----LSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAE 1915
Cdd:COG1196    195 LGELERQLEPLERQAEKAERY-RELKEELKELeaellLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELR 273

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1916 EEKDDLEERLmnqlaelngsignycqdvTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQG 1995
Cdd:COG1196    274 LELEELELEL------------------EEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEEL 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1996 AQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITK---ENLAQAVEHRKKA 2072
Cdd:COG1196    336 EEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAaqlEELEEAEEALLER 415

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2073 QAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALRREKV 2152
Cdd:COG1196    416 LERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLL 495


                   ....
gi 1034632655 2153 HLEE 2156
Cdd:COG1196    496 LLEA 499
PTZ00121 PTZ00121
MAEBL; Provisional
 1582-2381 1.93e-08

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 60.93  E-value: 1.93e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1582 KEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQE---LYGKLRSTEANKKE 1658
Cdd:PTZ00121  1153 RVEIARKAEDARKAEEARKAEDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEearKAEDAKKAEAVKKA 1232

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1659 TEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHPAGDTAKECMETLLSSNASMKEELERV-------- 1730
Cdd:PTZ00121  1233 EEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKAdeakkkae 1312

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1731 -KMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQanleatEKHDNQTNVTEEGTQSIPGETEEQDSLSMSTRPT 1809
Cdd:PTZ00121  1313 eAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEA------EAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKK 1386

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1810 cSESVPSAKSANPAVSKDFSSHDEINNYL---QQIDQLK---ERIAGLEEEKQKNKEFSQTLENEKNtllSQISTKDGEL 1883
Cdd:PTZ00121  1387 -AEEKKKADEAKKKAEEDKKKADELKKAAaakKKADEAKkkaEEKKKADEAKKKAEEAKKADEAKKK---AEEAKKAEEA 1462

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1884 KMLQEEVTKMNLLNQQiQEELSRVTKLKETAEEEKDDLEERLMNQLAElngsigNYCQDVTDAQIKNELLESEMKNLKKC 1963
Cdd:PTZ00121  1463 KKKAEEAKKADEAKKK-AEEAKKADEAKKKAEEAKKKADEAKKAAEAK------KKADEAKKAEEAKKADEAKKAEEAKK 1535

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1964 VSELEEEKQQLVKEKTKVESEIRK-EYLEKIQGAQKEpgnkshaKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVK 2042
Cdd:PTZ00121  1536 ADEAKKAEEKKKADELKKAEELKKaEEKKKAEEAKKA-------EEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMK 1608

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2043 ALEFVQTESQKdleITKENLAQAVEHRKKaqAELASFKVLLDDTQSEAARVLADNLKLKKELQSNK---ESVKSQMKQKD 2119
Cdd:PTZ00121  1609 AEEAKKAEEAK---IKAEELKKAEEEKKK--VEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKaeeDKKKAEEAKKA 1683

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2120 EDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKD---KEVQQLQENLDSTVTQLAAFTKSMSSL 2196
Cdd:PTZ00121  1684 EEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEeakKEAEEDKKKAEEAKKDEEEKKKIAHLK 1763

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2197 QDDRDRVIDEAKKWERKFSDAIQSKEEEIRLKEDNcsVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQTEVQLQQK 2276
Cdd:PTZ00121  1764 KEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDK--KIKDIFDNFANIIEGGKEGNLVINDSKEMEDSAIKEVADSKNM 1841

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2277 VCDtlqgENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYE 2356
Cdd:PTZ00121  1842 QLE----EADAFEKHKFNKNNENGEDGNKEADFNKEKDLKEDDEEEIEEADEIEKIDKDDIEREIPNNNMAGKNNDIIDD 1917

                          810       820
                   ....*....|....*....|....*
gi 1034632655 2357 QLETDLQASRELTSRLHEEINMKEQ 2381
Cdd:PTZ00121  1918 KLDKDEYIKRDAEETREEIIKISKK 1942
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1160-1651 2.08e-08

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 60.44  E-value: 2.08e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1160 ELEEKILALEKEKEQLQKKLQEAltsrKAILKKAQEKerhlREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQV 1239
Cdd:PRK02224   217 ELDEEIERYEEQREQARETRDEA----DEVLEEHEER----REELETLEAEIEDLRETIAETEREREELAEEVRDLRERL 288

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1240 ---RESIDGKLPSTDQQESCSSTPGLEEPLFKATEQHHTQPVLESNLcpDWPSHSEDASALQGgtSVAQIKAQLKEIEAE 1316
Cdd:PRK02224   289 eelEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRV--AAQAHNEEAESLRE--DADDLEERAEELREE 364

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1317 KVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLE-HLRELQPKLDE 1395
Cdd:PRK02224   365 AAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEaTLRTARERVEE 444

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1396 LQKL---------------------ISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKA------LHTQLEMQAK- 1447
Cdd:PRK02224   445 AEALleagkcpecgqpvegsphvetIEEDRERVEELEAELEDLEEEVEEVEERLERAEDLVEAedrierLEERREDLEEl 524

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1448 --EHDERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVES- 1524
Cdd:PRK02224   525 iaERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLERIRTLLAAIADa 604

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1525 ---------QVSAQNKEKDTVLGRLALLQEERDKLITEMDRSLLEN-----QSLSSSCESLKLALEGLTEDKEKLVKEIE 1590
Cdd:PRK02224   605 edeierlreKREALAELNDERRERLAEKRERKRELEAEFDEARIEEaredkERAEEYLEQVEEKLDELREERDDLQAEIG 684

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1034632655 1591 SLKSSkIAESTEWQEKHKELQKEYEILLQSYENVSneaeriqhvveavrqEKQELYGKLRS 1651
Cdd:PRK02224   685 AVENE-LEELEELRERREALENRVEALEALYDEAE---------------ELESMYGDLRA 729
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1828-2045 2.14e-08

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 59.39  E-value: 2.14e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1828 FSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEvtkMNLLNQQIQEELSRV 1907
Cdd:COG4942     16 AAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQE---LAALEAELAELEKEI 92

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1908 TKLKETAEEEKDDLEERL-----MNQLAELNGSIGNycQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVE 1982
Cdd:COG4942     93 AELRAELEAQKEELAELLralyrLGRQPPLALLLSP--EDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELE 170

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1034632655 1983 SEiRKEYLEKIQGAQKEpgnkshAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALE 2045
Cdd:COG4942    171 AE-RAELEALLAELEEE------RAALEALKAERQKLLARLEKELAELAAELAELQQEAEELE 226
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2212-2772 2.23e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 60.34  E-value: 2.23e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2212 RKFSDAIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELKINISRLEHDKQiwesKAQTEVQLQQKvcdTLQGENKELLSQ 2291
Cdd:COG1196    235 RELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELE----EAQAEEYELLA---ELARLEQDIARL 307

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2292 LEETRHLyhssQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSR 2371
Cdd:COG1196    308 EERRREL----EERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEE 383

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2372 LHEEINMKEQKIISLLSGKEEAIQV--AIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKK 2449
Cdd:COG1196    384 LAEELLEALRAAAELAAQLEELEEAeeALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLE 463

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2450 ENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEErhlsiiLEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLD 2529
Cdd:COG1196    464 LLAELLEEAALLEAALAELLEELAEAAARLLLLLE------AEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYE 537

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2530 AELIQYREDLNQVITIKDSQQ-KQLLEVQLQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSKEIESLKV 2608
Cdd:COG1196    538 AALEAALAAALQNIVVEDDEVaAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYV 617

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2609 SISQLTRQVTALQEEGTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELVCVQKEAAKKVGEIEDKLKKELKHLHH 2688
Cdd:COG1196    618 LGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEE 697

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2689 DAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKGLTAQIQSFG---------------------RSMSSLQNSRD 2747
Cdd:COG1196    698 ALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEelleeealeelpeppdleeleRELERLEREIE 777

                          570       580       590
                   ....*....|....*....|....*....|..
gi 1034632655 2748 H-------ANEELDELKRKYDASLKELAQLKE 2772
Cdd:COG1196    778 AlgpvnllAIEEYEELEERYDFLSEQREDLEE 809
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 48-954 4.10e-08

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 59.70  E-value: 4.10e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655   48 EDVQERLAYAEQLVVELKDIIRQKDVQLQQkdeaLQEERKAADNKIKKLKLHAKAKLTSLNKYIEEMKAQGGTVlptepq 127
Cdd:TIGR02169  173 EKALEELEEVEENIERLDLIIDEKRQQLER----LRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAI------ 242

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  128 sEEQLSKHDKSSTEEEMEIEKIKHKLQEKEELISTLQAQLTQAQAEQPAQSSTEMEEfvmmkqqlqekeefistLQAQLS 207
Cdd:TIGR02169  243 -ERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGE-----------------LEAEIA 304

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  208 QTQAEQAAQVVREKDARFETQvrlhedellqlvtQADVEtemqqkLRVLQRKLEEHEESLVGRAQVVDLLQQELTAAEQR 287
Cdd:TIGR02169  305 SLERSIAEKERELEDAEERLA-------------KLEAE------IDKLLAEIEELEREIEEERKRRDKLTEEYAELKEE 365

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  288 NQILSQQLQQMEAEHNTLRNTVETEREESKILLEKMElevaerklsfhNLQEEMHHLLEQFEQAGQAQAELESRYSALEQ 367
Cdd:TIGR02169  366 LEDLRAELEEVDKEFAETRDELKDYREKLEKLKREIN-----------ELKRELDRLQEELQRLSEELADLNAAIAGIEA 434

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  368 KHKAEMEEKTSHILSLQKTGQELQSACDALKDQNSKLLQDKNEqavqsaqtIQQLEDQLQQKSKEISQFLNRLPLQQHET 447
Cdd:TIGR02169  435 KINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEE--------YDRVEKELSKLQRELAEAEAQARASEERV 506

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  448 ASQTSFPDVYNEGTQAV---TEENIASLQKRVVELENEKGAlllssiELEELKAENEKLSSQITLLEAQNRTGEAdrevS 524
Cdd:TIGR02169  507 RGGRAVEEVLKASIQGVhgtVAQLGSVGERYATAIEVAAGN------RLNNVVVEDDAVAKEAIELLKRRKAGRA----T 576

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  525 EISIVDIANKRSSSAEESGQDVLentfsqkhkELSVLLLEMKEAQEEIAFLKLQLQG-KRAEEADHEVLDQKEMKQMEGE 603
Cdd:TIGR02169  577 FLPLNKMRDERRDLSILSEDGVI---------GFAVDLVEFDPKYEPAFKYVFGDTLvVEDIEAARRLMGKYRMVTLEGE 647

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  604 GIAP---IKMKVFLEDTGQDFPLMPNEESSLPAVEKEQASTEHQSRTSEEISLNDAGVELKSTKQDGDKSLSAVPDIGQC 680
Cdd:TIGR02169  648 LFEKsgaMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQ 727

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  681 HQDELERLKSQILELELNFHKAQEIYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLSQVKElsmvtE 760
Cdd:TIGR02169  728 LEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSRIPEIQAELS-----K 802

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  761 LRAQVKQLEMNLAEAERQ-RRLDYESQTAHDnllteqihslsiEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQL 839
Cdd:TIGR02169  803 LEEEVSRIEARLREIEQKlNRLTLEKEYLEK------------EIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEEL 870

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  840 QNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTEkMVQLNEE 919
Cdd:TIGR02169  871 EELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGE-DEEIPEE 949

                          890       900       910
                   ....*....|....*....|....*....|....*
gi 1034632655  920 KFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEV 954
Cdd:TIGR02169  950 ELSLEDVQAELQRVEEEIRALEPVNMLAIQEYEEV 984
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1414-1933 4.23e-08

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 59.28  E-value: 4.23e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1414 LSEKEAALTKIQTEI--IEQEDLIKALHTqLEMQAKEHDERIKQLQVE---LCEMKQKPEEIGEESRAKQQIQRKLQAAL 1488
Cdd:PRK02224   182 LSDQRGSLDQLKAQIeeKEEKDLHERLNG-LESELAELDEEIERYEEQreqARETRDEADEVLEEHEERREELETLEAEI 260

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1489 ----ISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMDRSLLENQSL 1564
Cdd:PRK02224   261 edlrETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAH 340

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1565 SSSCESLK---LALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQE 1641
Cdd:PRK02224   341 NEEAESLRedaDDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREE 420

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1642 KQELYGKLRSTEANKKETEKQLQEAEQEMEE----------MKEKMRKFAKSKQQKILELEEENDRLRAEVhpagdtake 1711
Cdd:PRK02224   421 RDELREREAELEATLRTARERVEEAEALLEAgkcpecgqpvEGSPHVETIEEDRERVEELEAELEDLEEEV--------- 491

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1712 cmetllssnASMKEELERVKMEYETlSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQANL-EATEKHDNQTNVTEEGTQ 1790
Cdd:PRK02224   492 ---------EEVEERLERAEDLVEA-EDRIERLEERREDLEELIAERRETIEEKRERAEELrERAAELEAEAEEKREAAA 561

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1791 SIPGETEEqdslSMSTRPTCSESVPSAKSANPAVSKDFSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKN 1870
Cdd:PRK02224   562 EAEEEAEE----AREEVAELNSKLAELKERIESLERIRTLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKR 637

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1034632655 1871 TLLSQIStkDGELKMLQEEvtkmnllNQQIQEELSRVTKLKETAEEEKDDLEER---LMNQLAELN 1933
Cdd:PRK02224   638 ELEAEFD--EARIEEARED-------KERAEEYLEQVEEKLDELREERDDLQAEigaVENELEELE 694
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1160-1701 4.73e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 59.18  E-value: 4.73e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1160 ELEEKILALEKEKEQLQK--KLQEALTSRKAILKKAqeKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQI 1237
Cdd:COG1196    197 ELERQLEPLERQAEKAERyrELKEELKELEAELLLL--KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRL 274

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1238 QVRESIDgklpstdqqescsstpgleeplfkateqhhtqpvlesnlcpdwpshsedasalqggtSVAQIKAQLKEIEAEK 1317
Cdd:COG1196    275 ELEELEL---------------------------------------------------------ELEEAQAEEYELLAEL 297

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1318 VELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLEHlrelqpKLDELQ 1397
Cdd:COG1196    298 ARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEE------ALLEAE 371

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1398 KLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVELCEMKQKPEEIGEESRAK 1477
Cdd:COG1196    372 AELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEE 451

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1478 QQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMDRS 1557
Cdd:COG1196    452 AELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIG 531

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1558 LLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKS-----------SKIAESTEWQEKHKELQKEYEILLQSYENVSN 1626
Cdd:COG1196    532 VEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAakagratflplDKIRARAALAAALARGAIGAAVDLVASDLREA 611

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1034632655 1627 EAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAE 1701
Cdd:COG1196    612 DARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAE 686
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1300-2178 5.11e-08

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 59.21  E-value: 5.11e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1300 GTSVAQIKAQLKEIEAEKVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQ 1379
Cdd:pfam02463  161 EAAGSRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERID 240

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1380 IagLEHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVE 1459
Cdd:pfam02463  241 L--LQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKE 318

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1460 LCEMKQKpeeigeesrakqqIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGR 1539
Cdd:pfam02463  319 SEKEKKK-------------AEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESER 385

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1540 LALLQEERDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQ 1619
Cdd:pfam02463  386 LSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDEL 465

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1620 SYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLR 1699
Cdd:pfam02463  466 ELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAI 545

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1700 AEVHPAGDTAKECMETLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQANLEATEKHD 1779
Cdd:pfam02463  546 STAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVV 625

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1780 NQTNVTEEGTQSIPGETEEQDSLSMstrptcsesVPSAKSANPAVSKDFSSHDEINNYLQQIDQLKERIAGLEEEKQKNK 1859
Cdd:pfam02463  626 EGILKDTELTKLKESAKAKESGLRK---------GVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILR 696

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1860 EFSQTLENEKNTLLSQISTKDGELKMLQEEVT-KMNLLNQQIQEELSRVTKLKETAEEEKDDLEERLMNQLAELNGSIGN 1938
Cdd:pfam02463  697 RQLEIKKKEQREKEELKKLKLEAEELLADRVQeAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKEL 776

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1939 YCQDVTDAQIKNElLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQgaqkepgnKSHAKELQELLKEKQQ 2018
Cdd:pfam02463  777 AEEREKTEKLKVE-EEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIK--------EEELEELALELKEEQK 847

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2019 EVKQLQKDCIRYQEKISALERTVKALEfvqtESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNL 2098
Cdd:pfam02463  848 LEKLAEEELERLEEEITKEELLQELLL----KEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERI 923

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2099 KLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQEN 2178
Cdd:pfam02463  924 KEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEE 1003
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1058-1923 7.42e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 58.53  E-value: 7.42e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1058 EIYLKQTISEKEVELQHIRKDLEEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEISENQAIIQKLITSNTDAsDGDSV 1137
Cdd:TIGR02168  213 ERYKELKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEEL-QKELY 291

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1138 ALVKEtvvisppctgssehwKPELEEKILALEKEKEQLQKKLQEAltsrKAILKKAQEKERHLREELKQQKDDYNRLQEQ 1217
Cdd:TIGR02168  292 ALANE---------------ISRLEQQKQILRERLANLERQLEEL----EAQLEELESKLDELAEELAELEEKLEELKEE 352

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1218 FDEQSKENENIGDQLRQLQIQVREsidgklpstDQQESCSSTPGLEEPLFKATEQHHTQPVLESNLcpdwpSHSEDasal 1297
Cdd:TIGR02168  353 LESLEAELEELEAELEELESRLEE---------LEEQLETLRSKVAQLELQIASLNNEIERLEARL-----ERLED---- 414

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1298 qggtSVAQIKAQLKEIEAEKVELELKVSSTtsELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQ 1377
Cdd:TIGR02168  415 ----RRERLQQEIEELLKKLEEAELKELQA--ELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQ 488

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1378 LQIAGLEHLRELQPKLDELQKLISKKEEDVSYLSGQLSEK-------EAALtkiqtEIIEQEDLIKALHTQLE--MQAKE 1448
Cdd:TIGR02168  489 ARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELisvdegyEAAI-----EAALGGRLQAVVVENLNaaKKAIA 563

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1449 HDERIKQLQVELCEMKQKPEeigeesrakQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSA 1528
Cdd:TIGR02168  564 FLKQNELGRVTFLPLDSIKG---------TEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNA 634

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1529 QNKEK-------------DTVLGRLALLQ--EERDKLITEMDRSLLENQS----LSSSCESLKLALEGLTEDKEKLVKEI 1589
Cdd:TIGR02168  635 LELAKklrpgyrivtldgDLVRPGGVITGgsAKTNSSILERRREIEELEEkieeLEEKIAELEKALAELRKELEELEEEL 714

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1590 ESLKSSKIAESTewqeKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEkqlqeaeQE 1669
Cdd:TIGR02168  715 EQLRKELEELSR----QISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAE-------AE 783

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1670 MEEMKEKMRKFAKSKQQKILELEEENDRLRAevhpagdtakecmetLLSSNASMKEELERVKMEYETLSKKFQSLMSEKD 1749
Cdd:TIGR02168  784 IEELEAQIEQLKEELKALREALDELRAELTL---------------LNEEAANLRERLESLERRIAATERRLEDLEEQIE 848

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1750 SLSEEVQDLKHQIEGNVSKQANLE-ATEKHDNQTNVTEEGTQSIPGETEEQDSLSMSTRPTCSESVPSAKSANPAVSKdf 1828
Cdd:TIGR02168  849 ELSEDIESLAAEIEELEELIEELEsELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQ-- 926

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1829 sSHDEINNYLQQIDQLKERIAgleEEKQKNKEFSQTLENEKNTLLSQIstkDGELKMLQEEVTKMNLLNQQIQEELSRVT 1908
Cdd:TIGR02168  927 -LELRLEGLEVRIDNLQERLS---EEYSLTLEEAEALENKIEDDEEEA---RRRLKRLENKIKELGPVNLAAIEEYEELK 999

                          890
                   ....*....|....*
gi 1034632655 1909 KLKETAEEEKDDLEE 1923
Cdd:TIGR02168 1000 ERYDFLTAQKEDLTE 1014
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1432-2177 8.31e-08

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 58.59  E-value: 8.31e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1432 EDLIKALHTQLEMQAKEH---DERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLA 1508
Cdd:pfam15921   88 KDLQRRLNESNELHEKQKfylRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTVHELEAAKCLKEDMLED 167

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1509 RGT-IERLTKSLADVESQVSAqnkekdtVLGRLALLQEERDKLITEMDR-SLLENQSLSSSCESLKLALEgltedkeklv 1586
Cdd:pfam15921  168 SNTqIEQLRKMMLSHEGVLQE-------IRSILVDFEEASGKKIYEHDSmSTMHFRSLGSAISKILRELD---------- 230

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1587 KEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYEnvsneaERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEA 1666
Cdd:pfam15921  231 TEISYLKGRIFPVEDQLEALKSESQNKIELLLQQHQ------DRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEII 304

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1667 EQEMEEMKEKMrkfakskQQKILELEEENDRLRAEVHPAGDTAKECMETLLSSNASMKEELERVKMEYETLSKKFQSLms 1746
Cdd:pfam15921  305 QEQARNQNSMY-------MRQLSDLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNL-- 375

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1747 eKDSLSEEVQDL-KHQIEGNVSKQANLEATEKHDNQTNVTEEGTQSIPGETEEQDSLSMSTRPTCSESVPSAKSANPAVS 1825
Cdd:pfam15921  376 -DDQLQKLLADLhKREKELSLEKEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMAAIQ 454

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1826 KDFSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKM----NLLNQQIQ 1901
Cdd:pfam15921  455 GKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEITKLrsrvDLKLQELQ 534

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1902 EELSRVTKLKETAEE---------EKDDLEERLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQ 1972
Cdd:pfam15921  535 HLKNEGDHLRNVQTEcealklqmaEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEFKILKD 614

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1973 QLVKEKTKVESEIRKEYLEKIQ----GAQKEPGNKSHAKELQELLKE---KQQEVKQLQKDC----IRYQEKISALERTV 2041
Cdd:pfam15921  615 KKDAKIRELEARVSDLELEKVKlvnaGSERLRAVKDIKQERDQLLNEvktSRNELNSLSEDYevlkRNFRNKSEEMETTT 694

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2042 KALEFVQTESQKDLEITKENL-------AQAVEHRKKAQAELASFKVLLDDTQSEaarvladnLKLKKELQSNKESVKSQ 2114
Cdd:pfam15921  695 NKLKMQLKSAQSELEQTRNTLksmegsdGHAMKVAMGMQKQITAKRGQIDALQSK--------IQFLEEAMTNANKEKHF 766

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1034632655 2115 MKQKDEDLERRLEQAEekhlKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQE 2177
Cdd:pfam15921  767 LKEEKNKLSQELSTVA----TEKNKMAGELEVLRSQERRLKEKVANMEVALDKASLQFAECQD 825
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2637-2940 9.52e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 58.41  E-value: 9.52e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2637 EEEVHRLSALFSSSQKRIAELEEelvcvQKEAAKKVGEIEDKLKK--------ELKHLHHDAGIMRNETETAEERVAELA 2708
Cdd:COG1196    185 EENLERLEDILGELERQLEPLER-----QAEKAERYRELKEELKEleaellllKLRELEAELEELEAELEELEAELEELE 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2709 RDLVEME-------QKLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKEQGLLNRERD 2781
Cdd:COG1196    260 AELAELEaeleelrLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEEL 339

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2782 ALLSETAFSMNSTEENSLSHLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKFR----KS 2857
Cdd:COG1196    340 EELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLerleRL 419

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2858 EEGKQRSAAQPSTSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELHPLKAQLQEYQDKTKAFQIMQEEL 2937
Cdd:COG1196    420 EEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEA 499


                   ...
gi 1034632655 2938 RQE 2940
Cdd:COG1196    500 EAD 502
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1386-1602 1.68e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 56.31  E-value: 1.68e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1386 LRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVELCEMKQ 1465
Cdd:COG4942     22 AAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEA 101

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1466 KPEEIGEESRAKQQIQRKLQAALI----SRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLA 1541
Cdd:COG4942    102 QKEELAELLRALYRLGRQPPLALLlspeDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLA 181

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1034632655 1542 LLQEERDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESTE 1602
Cdd:COG4942    182 ELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 545-1435 1.69e-07

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 57.37  E-value: 1.69e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  545 DVLENTFSQKHKELSVLLLEMKEAQEEIAFLKLQLQGKRAEEADHEVLDQkemkqmegegiapikmkvfledtgqdfplm 624
Cdd:TIGR02168  228 ALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVS------------------------------ 277

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  625 pneesslpavEKEQASTEHQSR---TSEEISlndagvELKSTKQDGDKSLSAVPDIGQCHQDELERLKSQILELELNFHK 701
Cdd:TIGR02168  278 ----------ELEEEIEELQKElyaLANEIS------RLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAE 341

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  702 AQEIYE---KNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLSQVKEL-SMVTELRAQVKQLEmnlaeaER 777
Cdd:TIGR02168  342 LEEKLEelkEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLnNEIERLEARLERLE------DR 415

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  778 QRRLDYESQTAHDNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHIS 857
Cdd:TIGR02168  416 RERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLE 495

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  858 SKVEELSQalsqkeleITKMDQLLLEKKRDVETLQQTIEEKdqqvteISFsmtekmvqlnEEKFSLGVEIkTLKEQLN-L 936
Cdd:TIGR02168  496 RLQENLEG--------FSEGVKALLKNQSGLSGILGVLSEL------ISV----------DEGYEAAIEA-ALGGRLQaV 550

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  937 LSRAEEAKKEQVEEDNEVSSG------LKQNYDEMSPAGQISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSR 1010
Cdd:TIGR02168  551 VVENLNAAKKAIAFLKQNELGrvtflpLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDD 630

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1011 LEEELANLKDESKKEIPLSE-----TERGEVEEDKENKEYSekcVTSKCQEIEIyLKQTISEKEVELQHIRKDLEEKLAA 1085
Cdd:TIGR02168  631 LDNALELAKKLRPGYRIVTLdgdlvRPGGVITGGSAKTNSS---ILERRREIEE-LEEKIEELEEKIAELEKALAELRKE 706

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1086 EEQFQALVKQMNQTLQDKTNQIDLLQAEISENQAIIQKLITSNTDASDGDSVALVKETVVisppctgssEHWKPELEEKI 1165
Cdd:TIGR02168  707 LEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEEL---------EERLEEAEEEL 777

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1166 LALEKEKEQLQ---KKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVREs 1242
Cdd:TIGR02168  778 AEAEAEIEELEaqiEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIES- 856

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1243 idgklpSTDQQEScsstpgLEEPLFKATEQHHtqpvlesnlcpdwpSHSEDASALQggTSVAQIKAQLKEIEAEKVELEL 1322
Cdd:TIGR02168  857 ------LAAEIEE------LEELIEELESELE--------------ALLNERASLE--EALALLRSELEELSEELRELES 908

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1323 KVSSTTSELTKKSEEVFQLQEQINKQGLEIESLK-TVSHEAEVHAESLQQKLESSQLQIAGLE-HLRELQPKLDELQKL- 1399
Cdd:TIGR02168  909 KRSELRRELEELREKLAQLELRLEGLEVRIDNLQeRLSEEYSLTLEEAEALENKIEDDEEEARrRLKRLENKIKELGPVn 988

                          890       900       910       920
                   ....*....|....*....|....*....|....*....|..
gi 1034632655 1400 ------ISKKEEDVSYLSGQLSEKEAALTKIQtEIIEQEDLI 1435
Cdd:TIGR02168  989 laaieeYEELKERYDFLTAQKEDLTEAKETLE-EAIEEIDRE 1029
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 682-1220 1.89e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 57.25  E-value: 1.89e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  682 QDELERLKSQILELELNFHKAQE---IYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLSQVKEL-SM 757
Cdd:COG1196    266 EAELEELRLELEELELELEEAQAeeyELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELeEE 345

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  758 VTELRAQVKQLEMNLAEAERQRRLDYESQTAHDnlltEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQS 837
Cdd:COG1196    346 LEEAEEELEEAEAELAEAEEALLEAEAELAEAE----EELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEE 421

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  838 QLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSM-TEKMVQL 916
Cdd:COG1196    422 ELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLlLLLEAEA 501

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  917 NEEKFSLGVEIKTLKEQLNLLSRA------EEAKKEQVEEDNEVSSGLKQNYDEMSPAGQISkeelqhefDLLKKENEQR 990
Cdd:COG1196    502 DYEGFLEGVKAALLLAGLRGLAGAvavligVEAAYEAALEAALAAALQNIVVEDDEVAAAAI--------EYLKAAKAGR 573

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  991 KRKLQAALINRKELLQRVSRLEEEL-------ANLKDESKKEIPLSETERGE--VEEDKENKEYSEKCVTSKCQEIEIYL 1061
Cdd:COG1196    574 ATFLPLDKIRARAALAAALARGAIGaavdlvaSDLREADARYYVLGDTLLGRtlVAARLEAALRRAVTLAGRLREVTLEG 653

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1062 KQTISEKEVELQHIRKDLEEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEISENQAIIQKLITSNTDASDGDSVALVK 1141
Cdd:COG1196    654 EGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAE 733

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1142 ETvvisppctgssehwkpELEEKILALEKEKEQLQKKLQEALTSRKAILKKAQEKERHLR----------EELKQQKDDY 1211
Cdd:COG1196    734 RE----------------ELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEalgpvnllaiEEYEELEERY 797


                   ....*....
gi 1034632655 1212 NRLQEQFDE 1220
Cdd:COG1196    798 DFLSEQRED 806
PTZ00121 PTZ00121
MAEBL; Provisional
 1304-1860 1.91e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 57.46  E-value: 1.91e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1304 AQIKAQLKEIEAEKVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTvsHEAEVHAESLQQKLESSQLQIAGL 1383
Cdd:PTZ00121  1320 AKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKK--EEAKKKADAAKKKAEEKKKADEAK 1397

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1384 EHLRELQPKLDELQKLIS--KKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQvelc 1461
Cdd:PTZ00121  1398 KKAEEDKKKADELKKAAAakKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKAD---- 1473

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1462 EMKQKPEEI--GEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGR 1539
Cdd:PTZ00121  1474 EAKKKAEEAkkADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKK 1553

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1540 LALLQEERDKLITEMDRSLLENQSLSS-SCESLKLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILL 1618
Cdd:PTZ00121  1554 AEELKKAEEKKKAEEAKKAEEDKNMALrKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKK 1633

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1619 QSYENVSNEAERIQHvVEAVRQEKQELYGKlRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRL 1698
Cdd:PTZ00121  1634 KVEQLKKKEAEEKKK-AEELKKAEEENKIK-AAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKE 1711

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1699 RAEVHPAGDTAKECMETLL-SSNASMKEELERVKMEY----ETLSKKFQSLMSEKDSLSEEVQDLKHQI------EGNVS 1767
Cdd:PTZ00121  1712 AEEKKKAEELKKAEEENKIkAEEAKKEAEEDKKKAEEakkdEEEKKKIAHLKKEEEKKAEEIRKEKEAVieeeldEEDEK 1791

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1768 KQANLEATEK--HDNQTNVTEEGTQSIP----------GETEEQDSLSMSTRPTCSESVPSAKSANPAVSKDFSSHDEIN 1835
Cdd:PTZ00121  1792 RRMEVDKKIKdiFDNFANIIEGGKEGNLvindskemedSAIKEVADSKNMQLEEADAFEKHKFNKNNENGEDGNKEADFN 1871

                          570       580
                   ....*....|....*....|....*
gi 1034632655 1836 NYLQQIDQLKERIAGLEEEKQKNKE 1860
Cdd:PTZ00121  1872 KEKDLKEDDEEEIEEADEIEKIDKD 1896
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1314-1977 2.12e-07

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 56.95  E-value: 2.12e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1314 EAEKVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGL-EHLRELQPK 1392
Cdd:TIGR04523   32 DTEEKQLEKKLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLnSDLSKINSE 111

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1393 LDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEhderIKQLQVELCEMKQKPEEIGE 1472
Cdd:TIGR04523  112 IKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQ----KEELENELNLLEKEKLNIQK 187

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1473 ESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLIT 1552
Cdd:TIGR04523  188 NIDKIKNKLLKLELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKK 267

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1553 EMDRSLLEnqslsssCESLKLALEGLTEDKEKLVKEIESLKSSKIAESTewQEKHKELQKEYEILLQSYENVSNEAERIQ 1632
Cdd:TIGR04523  268 QLSEKQKE-------LEQNNKKIKELEKQLNQLKSEISDLNNQKEQDWN--KELKSELKNQEKKLEEIQNQISQNNKIIS 338

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1633 HVVEAVRQEKQELYGKLRSTEANKKETEKqlqeaeqemeemkekmrkfaksKQQKILELEEENDRLraevhpagdtaKEC 1712
Cdd:TIGR04523  339 QLNEQISQLKKELTNSESENSEKQRELEE----------------------KQNEIEKLKKENQSY-----------KQE 385

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1713 METLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQANLeatEKHDNQTNVTEEGTQSI 1792
Cdd:TIGR04523  386 IKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDL---TNQDSVKELIIKNLDNT 462

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1793 PGETEEQDSlsmstrpTCSESVPSAKSANPAVSKDFSSH-DEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNT 1871
Cdd:TIGR04523  463 RESLETQLK-------VLSRSINKIKQNLEQKQKELKSKeKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKE 535

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1872 LLSQISTKDGELKMLQEEVTKMNL------LNQQIQEELSRVTKLKETAEEEKDDLEER------LMNQLAELNGSIGNY 1939
Cdd:TIGR04523  536 KESKISDLEDELNKDDFELKKENLekeideKNKEIEELKQTQKSLKKKQEEKQELIDQKekekkdLIKEIEEKEKKISSL 615

                          650       660       670
                   ....*....|....*....|....*....|....*...
gi 1034632655 1940 CQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKE 1977
Cdd:TIGR04523  616 EKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKET 653
PTZ00121 PTZ00121
MAEBL; Provisional
 701-1228 2.68e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 57.07  E-value: 2.68e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  701 KAQEIYEKNLDEKAKEISNLNQLIE--EFKKNADNNSSAFTALSEERDQLLSQVKELSMVTELRAQVKQLEMNLAEAERQ 778
Cdd:PTZ00121  1285 KAEEKKKADEAKKAEEKKKADEAKKkaEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEE 1364

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  779 RRLDYESQTAHDNLLTEQIHSLSIEAKSKD---VKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVL----EGAE 851
Cdd:PTZ00121  1365 KAEAAEKKKEEAKKKADAAKKKAEEKKKADeakKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAkkkaEEAK 1444

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  852 RVRHISSKVEELSQA--LSQKELEITKMDQLL--LEKKRDVETLQQTIEEKDQQVTEISFSMTEKMvqlNEEKFSLGVEI 927
Cdd:PTZ00121  1445 KADEAKKKAEEAKKAeeAKKKAEEAKKADEAKkkAEEAKKADEAKKKAEEAKKKADEAKKAAEAKK---KADEAKKAEEA 1521

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  928 KTLKEqlnlLSRAEEAKKEQVEEDNEVssglKQNYDEMSPAGQISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQR 1007
Cdd:PTZ00121  1522 KKADE----AKKAEEAKKADEAKKAEE----KKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEAR 1593

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1008 VSRLEEELANLKDESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIYLKQTISEKEVELQHIRKDLEEKLAAEE 1087
Cdd:PTZ00121  1594 IEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEED 1673

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1088 QFQAlvKQMNQTLQDKTNQIDLLQAEISENQaiiqklitsntdasdgdsvalvketvvisppctgssehwKPELEEKILA 1167
Cdd:PTZ00121  1674 KKKA--EEAKKAEEDEKKAAEALKKEAEEAK---------------------------------------KAEELKKKEA 1712

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1034632655 1168 LEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENI 1228
Cdd:PTZ00121  1713 EEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEI 1773
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1579-2156 5.57e-07

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 55.84  E-value: 5.57e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1579 TEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYENVSNEAERIqhvvEAVRQEKQELYGKLRSTEANKKE 1658
Cdd:PRK03918   188 TENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEI----EELEKELESLEGSKRKLEEKIRE 263

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1659 TEKQLQEAEQEMEEMKEKM----------------RKFAKSKQQKILELEEENDRLRAEVhpagdtakECMETLLSSNAS 1722
Cdd:PRK03918   264 LEERIEELKKEIEELEEKVkelkelkekaeeyiklSEFYEEYLDELREIEKRLSRLEEEI--------NGIEERIKELEE 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1723 MKEELERVKMEYETLSKKFQSLmSEKDSLSEEVQDLKHQIEGNVSKQANL---EATEKHDNQTNVTEEGTQSIPGETEEQ 1799
Cdd:PRK03918   336 KEERLEELKKKLKELEKRLEEL-EERHELYEEAKAKKEELERLKKRLTGLtpeKLEKELEELEKAKEEIEEEISKITARI 414

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1800 DSLS--MSTRPTCSESVPSAKSANPAVSKDFSSHDE---INNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKN---T 1871
Cdd:PRK03918   415 GELKkeIKELKKAIEELKKAKGKCPVCGRELTEEHRkelLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKkesE 494

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1872 LLSQISTKDgELKMLQEEVTKMNLlnqqiqEELSRVTKLKETAEEEKDDLEERLMNQLAELNgsignycqdvtdaqiKNE 1951
Cdd:PRK03918   495 LIKLKELAE-QLKELEEKLKKYNL------EELEKKAEEYEKLKEKLIKLKGEIKSLKKELE---------------KLE 552

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1952 LLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIqgaqkepgnkshaKELQELLKEkQQEVKQLQKDCIRYQ 2031
Cdd:PRK03918   553 ELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERL-------------KELEPFYNE-YLELKDAEKELEREE 618

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2032 EKISALERTVKALEFVQTESQKDLEITKENLAQAveHRKKAQAELASFKVLLDDTQSEAARVLADnlklKKELQSNKESV 2111
Cdd:PRK03918   619 KELKKLEEELDKAFEELAETEKRLEELRKELEEL--EKKYSEEEYEELREEYLELSRELAGLRAE----LEELEKRREEI 692

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*..
gi 1034632655 2112 KSQMKQKDEDLERRLEQAEEKHLKEK--KNMQEKLDALRREKVHLEE 2156
Cdd:PRK03918   693 KKTLEKLKEELEEREKAKKELEKLEKalERVEELREKVKKYKALLKE 739
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 988-1592 6.58e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 55.33  E-value: 6.58e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  988 EQRKRKLQAALINRKELLQRVSRLEEELANLKDESKKEiplsETERGEVEEDKENkeysekcvtskcqeieiyLKQTISE 1067
Cdd:COG1196    221 ELKELEAELLLLKLRELEAELEELEAELEELEAELEEL----EAELAELEAELEE------------------LRLELEE 278

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1068 KEVELQHIRKDLEEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEISENQAIIQKLITSntdasdgdsvalvketvvis 1147
Cdd:COG1196    279 LELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEE-------------------- 338

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1148 ppctgssehwKPELEEKILALEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQ----------KDDYNRLQEQ 1217
Cdd:COG1196    339 ----------LEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELlealraaaelAAQLEELEEA 408

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1218 FDEQSKENENIGDQLRQLQIQVRESIDGKLPSTDQQESCSSTPGLEEPLFKATEQHHTQPVLESNLcpdwpshsEDASAL 1297
Cdd:COG1196    409 EEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAAL--------LEAALA 480

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1298 QGGTSVAQIKAQLKEIEAEKVELELKVSSTTSELTKK-----SEEVFQLQEQINKQGLEIE-----SLKTVSHEAEVHAE 1367
Cdd:COG1196    481 ELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAglrglAGAVAVLIGVEAAYEAALEaalaaALQNIVVEDDEVAA 560

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1368 SLQQKLESSQLQIAGLEHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAK 1447
Cdd:COG1196    561 AAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAV 640

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1448 EHDERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVS 1527
Cdd:COG1196    641 TLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEE 720

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1034632655 1528 AQNKEKDTVLGRLALLQEERDKLITEMDRSLLENQslssscESLKLALEGLTEDKEKLVKEIESL 1592
Cdd:COG1196    721 LEEEALEEQLEAEREELLEELLEEEELLEEEALEE------LPEPPDLEELERELERLEREIEAL 779
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1946-2687 8.60e-07

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 54.98  E-value: 8.60e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1946 AQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQK 2025
Cdd:pfam02463  179 IEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQ 258

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2026 DciryQEKISALERTVKALEFVQTESQKdleITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQ 2105
Cdd:pfam02463  259 E----IEKEEEKLAQVLKENKEEEKEKK---LQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELK 331

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2106 SNKESVKSQMKQKDEdlerrLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQEnldstvtq 2185
Cdd:pfam02463  332 KEKEEIEELEKELKE-----LEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELE-------- 398

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2186 LAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELKINISRLEHDKQIWES 2265
Cdd:pfam02463  399 LKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQ 478

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2266 KAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQE 2345
Cdd:pfam02463  479 LVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATAD 558

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2346 ADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKIISLLSGKEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIV 2425
Cdd:pfam02463  559 EVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLK 638

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2426 LEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRivgdyQQLEERHLSIILEKDQLIQEAAAENN 2505
Cdd:pfam02463  639 ESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAES-----ELAKEEILRRQLEIKKKEQREKEELK 713

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2506 KLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDSQQKQLLEVQLQQNKELENKYAKLEEKLKESEEANEDL 2585
Cdd:pfam02463  714 KLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKE 793

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2586 RRSFNALQEEKQDLSKEIESLKVSISQLTRQVTALQEEGTLGLYHAQLKVKEEEvhrLSALFSSSQKRIAELEEELVCVQ 2665
Cdd:pfam02463  794 EKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQK---LEKLAEEELERLEEEITKEELLQ 870

                          730       740
                   ....*....|....*....|..
gi 1034632655 2666 KEAAKKVGEIEDKLKKELKHLH 2687
Cdd:pfam02463  871 ELLLKEEELEEQKLKDELESKE 892
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 321-1136 9.29e-07

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 55.06  E-value: 9.29e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  321 EKMELEVAERKLSFHNLQEEMHHLLEQFEQAGQAQAELESRYSALEQKHkaemEEKTSHILSLQKTGQELQSACDALKdq 400
Cdd:TIGR02168  221 ELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKL----EELRLEVSELEEEIEELQKELYALA-- 294

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  401 nsKLLQDKNEQAVQSAQTIQQLEDQLQQKSKEISQFLNRLPLQQHETASQtsfpdvynEGTQAVTEENIASLQKRVVELE 480
Cdd:TIGR02168  295 --NEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAEL--------EEKLEELKEELESLEAELEELE 364

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  481 NEKGALLLSSIELEElkaENEKLSSQITLLEAQNRTGEADREVSEISIVDIA---NKRSSSAEESGQDVLENTFSQKHKE 557
Cdd:TIGR02168  365 AELEELESRLEELEE---QLETLRSKVAQLELQIASLNNEIERLEARLERLEdrrERLQQEIEELLKKLEEAELKELQAE 441

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  558 LSVLLLEMKEAQEEIAFLKLQLQGKRAEEADHEVLDQKEMKQMEgEGIAPIKMKVFLEDTGQDFPlmpneESSLPAVEKE 637
Cdd:TIGR02168  442 LEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELA-QLQARLDSLERLQENLEGFS-----EGVKALLKNQ 515

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  638 QASTEHQSRTSEEISLnDAGVELKSTKQDGDKSLSAVPDIGQCHQDELERLKsqilelELNFHKAQEIYEKNLDEKAKEI 717
Cdd:TIGR02168  516 SGLSGILGVLSELISV-DEGYEAAIEAALGGRLQAVVVENLNAAKKAIAFLK------QNELGRVTFLPLDSIKGTEIQG 588

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  718 SNLNQL--IEEFKKNADNNSSAFTALSEERDQLLSQVKelsMVTelraqvkqlemNLAEAERQRRLDYESQtahdNLLTE 795
Cdd:TIGR02168  589 NDREILknIEGFLGVAKDLVKFDPKLRKALSYLLGGVL---VVD-----------DLDNALELAKKLRPGY----RIVTL 650

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  796 QIHSLSIE------AKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVlegaervrhisskvEELSQALSQ 869
Cdd:TIGR02168  651 DGDLVRPGgvitggSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKEL--------------EELEEELEQ 716

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  870 KELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNEEKFSLGVEIKTLKEQlnllsraeEAKKEQVE 949
Cdd:TIGR02168  717 LRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEA--------EAEIEELE 788

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  950 EDNEVSSGLKQNYDEMSpagqiskEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELANLkdesKKEIPLS 1029
Cdd:TIGR02168  789 AQIEQLKEELKALREAL-------DELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEEL----SEDIESL 857

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1030 ETERGEVEEDKENKEYSEKCVTSKCQEIEIYLKQTISEKEVELQHIRKDLEEKLAAEEQFQAL---VKQMNQTLQDKTNQ 1106
Cdd:TIGR02168  858 AAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELrekLAQLELRLEGLEVR 937

                          810       820       830
                   ....*....|....*....|....*....|
gi 1034632655 1107 IDLLQAEISENQAIIQKLITSNTDASDGDS 1136
Cdd:TIGR02168  938 IDNLQERLSEEYSLTLEEAEALENKIEDDE 967
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 1415-2908 1.06e-06

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 55.06  E-value: 1.06e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1415 SEKEAALTKIQTEIIEQEDLIKALHTQLEmqakEHDERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAAL--ISRK 1492
Cdd:TIGR01612  540 KEIEAGLKESYELAKNWKKLIHEIKKELE----EENEDSIHLEKEIKDLFDKYLEIDDEIIYINKLKLELKEKIknISDK 615

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1493 -EALKENKSLQEELSLARGTIERLTK-SLADVESQVSAQNKEKDTVLGRLA-LLQEERDKLITEMDRSLLENQSLSssce 1569
Cdd:TIGR01612  616 nEYIKKAIDLKKIIENNNAYIDELAKiSPYQVPEHLKNKDKIYSTIKSELSkIYEDDIDALYNELSSIVKENAIDN---- 691

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1570 slklaleglTEDKEKLvkeiESLKSSKIAESTEWQEKHKELQKEYeilLQSYENVSNEAERIqhVVEAVRQEKQELYGKL 1649
Cdd:TIGR01612  692 ---------TEDKAKL----DDLKSKIDKEYDKIQNMETATVELH---LSNIENKKNELLDI--IVEIKKHIHGEINKDL 753

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1650 RSTEANKKETEKQLQEAEQEMEEMKEKMRKFakskQQKILELEEE-NDRLR------AEVHPAGDTAKECMETLLSSNAS 1722
Cdd:TIGR01612  754 NKILEDFKNKEKELSNKINDYAKEKDELNKY----KSKISEIKNHyNDQINidnikdEDAKQNYDKSKEYIKTISIKEDE 829

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1723 MKEELERVK-MEYETLSK-----KFQSLMSEK-DSLSEEVQDLKHQIEGNVSKQANLEATEKHDNQTNVTEEGTQSIpge 1795
Cdd:TIGR01612  830 IFKIINEMKfMKDDFLNKvdkfiNFENNCKEKiDSEHEQFAELTNKIKAEISDDKLNDYEKKFNDSKSLINEINKSI--- 906

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1796 teEQDSLSMSTRPTCSESVPSAKSANPAVSKDFSSHDEINNYLQQ-IDQLKEriAGLEEEKQKNKeFSQTLENEKNTL-- 1872
Cdd:TIGR01612  907 --EEEYQNINTLKKVDEYIKICENTKESIEKFHNKQNILKEILNKnIDTIKE--SNLIEKSYKDK-FDNTLIDKINELdk 981

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1873 ------LSQISTKDGEL----KMLQEEV--TKMNLLNQQIQEELSRVTKLketaEEEKDDLEERLMNQLAELNGSIGNYC 1940
Cdd:TIGR01612  982 afkdasLNDYEAKNNELikyfNDLKANLgkNKENMLYHQFDEKEKATNDI----EQKIEDANKNIPNIEIAIHTSIYNII 1057

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1941 QDVTDAQIKN-ELLESE-MKNLKKCVSELEEEKQQL----VKEKTKVESEIRKEYLEKIQGAQKEPGNK--SHAKELQEL 2012
Cdd:TIGR01612 1058 DEIEKEIGKNiELLNKEiLEEAEINITNFNEIKEKLkhynFDDFGKEENIKYADEINKIKDDIKNLDQKidHHIKALEEI 1137

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2013 LKEKQQEVKQLQKdciryqeKISALERTVKALefVQTESQKDLEITKENLAQAVEHRKKAQAELasfKVLLddtqSEAAR 2092
Cdd:TIGR01612 1138 KKKSENYIDEIKA-------QINDLEDVADKA--ISNDDPEEIEKKIENIVTKIDKKKNIYDEI---KKLL----NEIAE 1201

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2093 VLADNLKLKK----ELQSNKESVKSQMKQKDEDLER--RLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQV--T 2164
Cdd:TIGR01612 1202 IEKDKTSLEEvkgiNLSYGKNLGKLFLEKIDEEKKKseHMIKAMEAYIEDLDEIKEKSPEIENEMGIEMDIKAEMETfnI 1281

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2165 LNKKDKEVQQLQENLDSTVTQLAafTKSMSSLQDD-RDRVIDEAKKWERKFSDAIQSKEEEIRLKEDNCSVLkdqlrqms 2243
Cdd:TIGR01612 1282 SHDDDKDHHIISKKHDENISDIR--EKSLKIIEDFsEESDINDIKKELQKNLLDAQKHNSDINLYLNEIANI-------- 1351

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2244 ihmeelkINISRLEHDKQIWEskaqtevqlqqkvcdtlqgENKELLSQLEETRHlyhSSQNELAKLESELKSLKDQLtdl 2323
Cdd:TIGR01612 1352 -------YNILKLNKIKKIID-------------------EVKEYTKEIEENNK---NIKDELDKSEKLIKKIKDDI--- 1399

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2324 snSLEKCKEQkgnLEGIIRQQEAD--IQNSKFSYEQL---ETDLQASRELTSRLHEEINMKEQKIISLLSGKEEAIQVAI 2398
Cdd:TIGR01612 1400 --NLEECKSK---IESTLDDKDIDecIKKIKELKNHIlseESNIDTYFKNADENNENVLLLFKNIEMADNKSQHILKIKK 1474

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2399 AELRQQHDKEIKELENLLSQEEEENIVLEEeNKKAVDKTNQLMETLKTIKKENIQQKAQLdSFVKSMSSLQNDRDRIVgd 2478
Cdd:TIGR01612 1475 DNATNDHDFNINELKEHIDKSKGCKDEADK-NAKAIEKNKELFEQYKKDVTELLNKYSAL-AIKNKFAKTKKDSEIII-- 1550

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2479 yQQLEERHLSIILE------------KDQL-IQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDaeliQYREDLNQVITI 2545
Cdd:TIGR01612 1551 -KEIKDAHKKFILEaekseqkikeikKEKFrIEDDAAKNDKSNKAAIDIQLSLENFENKFLKIS----DIKKKINDCLKE 1625

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2546 KDSQQKQL--LEVQLQQNKELENKYAKLEEKLKESEEANEdlRRSFNALQEEKQDLSKEIESLKVSISQLTRQVtalqEE 2623
Cdd:TIGR01612 1626 TESIEKKIssFSIDSQDTELKENGDNLNSLQEFLESLKDQ--KKNIEDKKKELDELDSEIEKIEIDVDQHKKNY----EI 1699

                         1290      1300      1310      1320      1330      1340      1350      1360
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2624 GTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELVCVQKEAAKKVGEIEDKLKKELKHLHHDAGIMRNETETAEER 2703
Cdd:TIGR01612 1700 GIIEKIKEIAIANKEEIESIKELIEPTIENLISSFNTNDLEGIDPNEKLEEYNTEIGDIYEEFIELYNIIAGCLETVSKE 1779

                         1370      1380      1390      1400      1410      1420      1430      1440
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2704 ---VAELARDLVEMEQKLLMVTKENKGLTA-----QIQSFGRSMSSLQNSRDHAN----EELDELKRKYDASLKELAQLK 2771
Cdd:TIGR01612 1780 pitYDEIKNTRINAQNEFLKIIEIEKKSKSylddiEAKEFDRIINHFKKKLDHVNdkftKEYSKINEGFDDISKSIENVK 1859

                         1450      1460      1470      1480      1490      1500      1510      1520
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2772 EQ-------GLLNRERDAL---------------------LSETAFSMNSTEENS--LSHLEKLNQQLLSkdeqllHLSS 2821
Cdd:TIGR01612 1860 NStdenllfDILNKTKDAYagiigkkyysykdeaekifinISKLANSINIQIQNNsgIDLFDNINIAILS------SLDS 1933

                         1530      1540      1550      1560      1570      1580      1590      1600
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2822 QLEDSYNQVQSFSKAMASLQNERDHLWNELEKFRKSEEGKQRSA---------AQPSTSPAEVQSLKKAMSSLQNDRDRL 2892
Cdd:TIGR01612 1934 EKEDTLKFIPSPEKEPEIYTKIRDSYDTLLDIFKKSQDLHKKEQdtlniifenQQLYEKIQASNELKDTLSDLKYKKEKI 2013

                         1610
                   ....*....|....*.
gi 1034632655 2893 LKELKNLQQQYLQINQ 2908
Cdd:TIGR01612 2014 LNDVKLLLHKFDELNK 2029
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 1305-2152 1.15e-06

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 54.67  E-value: 1.15e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1305 QIKAQLKEIEAEKvELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLES----SQLQI 1380
Cdd:TIGR00606  225 QITSKEAQLESSR-EIVKSYENELDPLKNRLKEIEHNLSKIMKLDNEIKALKSRKKQMEKDNSELELKMEKvfqgTDEQL 303

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1381 AGLEH-----LRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTK-------IQTEIIEQEDLIKALHTQLEMQAKE 1448
Cdd:TIGR00606  304 NDLYHnhqrtVREKERELVDCQRELEKLNKERRLLNQEKTELLVEQGRlqlqadrHQEHIRARDSLIQSLATRLELDGFE 383

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1449 HDERIKQLQVELCEMKQKPEEigEESRAKQQIQRKLQAALISRKEALKEnksLQEELSLARGTIERLTKSLADVESQvsa 1528
Cdd:TIGR00606  384 RGPFSERQIKNFHTLVIERQE--DEAKTAAQLCADLQSKERLKQEQADE---IRDEKKGLGRTIELKKEILEKKQEE--- 455

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1529 qnkekdtvlgrLALLQEERDKLITEMDRSLLENQSLSSSCESLKLALE-GLTEDKEKLVKEIESLKSSKIAESTEWQEKH 1607
Cdd:TIGR00606  456 -----------LKFVIKELQQLEGSSDRILELDQELRKAERELSKAEKnSLTETLKKEVKSLQNEKADLDRKLRKLDQEM 524

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1608 KELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLrSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQk 1687
Cdd:TIGR00606  525 EQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLL-GYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKELAS- 602

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1688 ileLEEENDRLRAEVHPAGDTAKECMETLLSSNASMKEE--LERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGN 1765
Cdd:TIGR00606  603 ---LEQNKNHINNELESKEEQLSSYEDKLFDVCGSQDEEsdLERLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSC 679

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1766 VSKQANLEATEKHDNQ-TNVTEEGTQSIPGETEEQDSLSMSTRptcsesvpsaKSANPAVSKDFSSHDEINNYLQQIDQL 1844
Cdd:TIGR00606  680 CPVCQRVFQTEAELQEfISDLQSKLRLAPDKLKSTESELKKKE----------KRRDEMLGLAPGRQSIIDLKEKEIPEL 749

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1845 KERIAGLEEEKQKNKEFSQtlenEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAE--------- 1915
Cdd:TIGR00606  750 RNKLQKVNRDIQRLKNDIE----EQETLLGTIMPEEESAKVCLTDVTIMERFQMELKDVERKIAQQAAKLQgsdldrtvq 825

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1916 ------EEKDDLEERLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEY 1989
Cdd:TIGR00606  826 qvnqekQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIK 905

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1990 LEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKEN-------- 2061
Cdd:TIGR00606  906 DAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKVKNIHGYMKDIENKIQDGKDDYLKQKETelntvnaq 985

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2062 LAQAVEHRKKAQAELASFKVLLdDTQSEAARVLADNLKLKK---ELQSNKESVKSQMKQKDEDLERRLEQAEEKhlkekk 2138
Cdd:TIGR00606  986 LEECEKHQEKINEDMRLMRQDI-DTQKIQERWLQDNLTLRKrenELKEVEEELKQHLKEMGQMQVLQMKQEHQK------ 1058

                          890
                   ....*....|....
gi 1034632655 2139 nMQEKLDALRREKV 2152
Cdd:TIGR00606 1059 -LEENIDLIKRNHV 1071
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1307-1917 1.26e-06

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 54.26  E-value: 1.26e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1307 KAQLKEIEAEKVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLEHL 1386
Cdd:TIGR04523  123 EVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELL 202

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1387 RELQPKLDELQKLISKKeedVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVELCEMKQK 1466
Cdd:TIGR04523  203 LSNLKKKIQKNKSLESQ---ISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQN 279

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1467 PEEIGEESRAKQQIQRKLQAAlisrkealkENKSLQEELSLARGTIERLTKSLADVESQVSAQNKekdtvlgRLALLQEE 1546
Cdd:TIGR04523  280 NKKIKELEKQLNQLKSEISDL---------NNQKEQDWNKELKSELKNQEKKLEEIQNQISQNNK-------IISQLNEQ 343

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1547 RDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKiaestewqekhkelqKEYEILLQSYENVSN 1626
Cdd:TIGR04523  344 ISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQI---------------NDLESKIQNQEKLNQ 408

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1627 EAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKIleleeendrlraevhpag 1706
Cdd:TIGR04523  409 QKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQL------------------ 470

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1707 dtakecmETLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQANLEATEKHDNQTnvte 1786
Cdd:TIGR04523  471 -------KVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESK---- 539

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1787 egTQSIPGETEEQDSlsmstrptcsesvpsaksanpaVSKDFSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLE 1866
Cdd:TIGR04523  540 --ISDLEDELNKDDF----------------------ELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKE 595

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1034632655 1867 NEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAEEE 1917
Cdd:TIGR04523  596 KEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQE 646
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1294-1530 2.68e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 52.46  E-value: 2.68e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1294 ASALQGGTSVAQIKAQLKEIEAEKVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKL 1373
Cdd:COG4942     13 LAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEI 92

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1374 ESSQLQIAGLEHlrELQPKLDELQKLISKKEEDV---SYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHD 1450
Cdd:COG4942     93 AELRAELEAQKE--ELAELLRALYRLGRQPPLALllsPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELE 170

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1451 ERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEALKENKSLQEELslaRGTIERLTKSLADVESQVSAQN 1530
Cdd:COG4942    171 AERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEEL---EALIARLEAEAAAAAERTPAAG 247
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 874-1762 2.97e-06

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 53.44  E-value: 2.97e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  874 ITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNE 953
Cdd:pfam02463  164 GSRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQ 243

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  954 VSSGLKQNYDEMSPAGQISKEELQHEFDLLKKENEqRKRKLQAALINRKELLQRVSRLEEELANLKDESKKEIPLSETER 1033
Cdd:pfam02463  244 ELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEE-KEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKE 322

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1034 GEVEEDKENKEYSEKCVTSKcqeieiyLKQTISEKEVELQHIRKDLEEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAE 1113
Cdd:pfam02463  323 KKKAEKELKKEKEEIEELEK-------ELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEE 395

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1114 ISENQAIIQKLITSNTDASDGDsvalvketvvisppctgssEHWKPELEEKILALEKEKEQLQKKLQEALTSRKAILKKA 1193
Cdd:pfam02463  396 ELELKSEEEKEAQLLLELARQL-------------------EDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQ 456

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1194 QEKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVRESIDGKLPSTDQQESCSSTPGLEEPLFKATEQH 1273
Cdd:pfam02463  457 ELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGV 536

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1274 HTQPVLESNLCPDWPSHSEDASALQGGTSVAQIKAQLKEIEAEKVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIE 1353
Cdd:pfam02463  537 AVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEAD 616

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1354 SLKTVSHEAEVHAESLQQK--LESSQLQIAGLEHLRELQPKLDELQKLISKKEEDVS--YLSGQLSEKEAALTKIQTEII 1429
Cdd:pfam02463  617 EDDKRAKVVEGILKDTELTklKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKelLEIQELQEKAESELAKEEILR 696

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1430 EQEDLIKALHTQLEMQAKEHDERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLAR 1509
Cdd:pfam02463  697 RQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKEL 776

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1510 GTIERLTKSLADVESQVSAQNKEKDTvlgrLALLQEERDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEI 1589
Cdd:pfam02463  777 AEEREKTEKLKVEEEKEEKLKAQEEE----LRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLA 852

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1590 ESLKSSKIAESTEWQEKHKELQKEYEILLQSYENVSNEAERiqhvvEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQE 1669
Cdd:pfam02463  853 EEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEE-----KEKEEKKELEEESQKLNLLEEKENEIEERIKEEA 927

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1670 MEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHpaGDTAKECMETLLSSNASMKEELERVKMEYETLSKKFQSLMSEKD 1749
Cdd:pfam02463  928 EILLKYEEEPEELLLEEADEKEKEENNKEEEEER--NKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKK 1005

                          890
                   ....*....|...
gi 1034632655 1750 SLSEEVQDLKHQI 1762
Cdd:pfam02463 1006 KLIRAIIEETCQR 1018
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 1378-1653 3.33e-06

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 53.01  E-value: 3.33e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1378 LQIAGLEhlRELQPKLDELQKL-----ISKKEED----VSYLSGQLSEKEAALTKIQTeIIEQEDLIKALhtQLEMQAKE 1448
Cdd:PRK05771     9 VLIVTLK--SYKDEVLEALHELgvvhiEDLKEELsnerLRKLRSLLTKLSEALDKLRS-YLPKLNPLREE--KKKVSVKS 83

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1449 HDERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQaaliSRKEALKENKSLQEELSLAR---------GTI-----ER 1514
Cdd:PRK05771    84 LEELIKDVEEELEKIEKEIKELEEEISELENEIKELE----QEIERLEPWGNFDLDLSLLLgfkyvsvfvGTVpedklEE 159

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1515 LTKSLADVESQVSAQNKEKDTVLgrLALLQEERDKLITEMDRSLLENQSLSSScESLKLALEGLTEDKEKLVKEIESLKs 1594
Cdd:PRK05771   160 LKLESDVENVEYISTDKGYVYVV--VVVLKELSDEVEEELKKLGFERLELEEE-GTPSELIREIKEELEEIEKERESLL- 235

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1034632655 1595 SKIAESTEwqekhkelqKEYEILLQSYENVSNEAERiqhvveavrqekQELYGKLRSTE 1653
Cdd:PRK05771   236 EELKELAK---------KYLEELLALYEYLEIELER------------AEALSKFLKTD 273
PRK11281 PRK11281
mechanosensitive channel MscK;
151-507 3.41e-06

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 52.99  E-value: 3.41e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  151 HKLQEKEEliSTLQAQLTQAQA--EQPAQSSTEMEEfvmMKQQLQEKEEFISTLQAQLSQTQAeQAAQVVREkdaRFETq 228
Cdd:PRK11281    51 QKLLEAED--KLVQQDLEQTLAllDKIDRQKEETEQ---LKQQLAQAPAKLRQAQAELEALKD-DNDEETRE---TLST- 120

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  229 vrLHEDELLQLVTQadVETEMQQklrvLQRKLEEHEESLVGRAQVVDLLQQELTAAEQRNQILSQQLQQMEAEHNTLRNT 308
Cdd:PRK11281   121 --LSLRQLESRLAQ--TLDQLQN----AQNDLAEYNSQLVSLQTQPERAQAALYANSQRLQQIRNLLKGGKVGGKALRPS 192

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  309 VETERE------ESKILLEKMELEVAERKLSFHNLQeemHHLLEqfEQAGQAQAELESRYSALEQKHKAEMEektshils 382
Cdd:PRK11281   193 QRVLLQaeqallNAQNDLQRKSLEGNTQLQDLLQKQ---RDYLT--ARIQRLEHQLQLLQEAINSKRLTLSE-------- 259

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  383 lqKTGQELQSACDALKDQNSKLLQDKNEQAVQSAQT-IQQLE--DQLQQKSKEISQFLNRlpLQQhetasqtsfpdvyne 459
Cdd:PRK11281   260 --KTVQEAQSQDEAARIQANPLVAQELEINLQLSQRlLKATEklNTLTQQNLRVKNWLDR--LTQ--------------- 320

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1034632655  460 gTQAVTEENIASLQkrvvelenekGALLLSSIELEELKA-----ENEKLSSQI 507
Cdd:PRK11281   321 -SERNIKEQISVLK----------GSLLLSRILYQQQQAlpsadLIEGLADRI 362
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 1326-2257 3.57e-06

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 53.13  E-value: 3.57e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1326 STTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLEHLRELQPKLDELQKLISKKEE 1405
Cdd:TIGR00606  166 SEGKALKQKFDEIFSATRYIKALETLRQVRQTQGQKVQEHQMELKYLKQYKEKACEIRDQITSKEAQLESSREIVKSYEN 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1406 DVSYLSGQLSEKEAALTKIQteiiEQEDLIKALH-TQLEMQAKEHDERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKL 1484
Cdd:TIGR00606  246 ELDPLKNRLKEIEHNLSKIM----KLDNEIKALKsRKKQMEKDNSELELKMEKVFQGTDEQLNDLYHNHQRTVREKEREL 321

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1485 QAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLIT------------ 1552
Cdd:TIGR00606  322 VDCQRELEKLNKERRLLNQEKTELLVEQGRLQLQADRHQEHIRARDSLIQSLATRLELDGFERGPFSErqiknfhtlvie 401

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1553 -EMDRSLLENQSLSSSCESLKLALEGLTE--------------DKEKLVKEIESLKSSK------IAESTEWQEKHKELQ 1611
Cdd:TIGR00606  402 rQEDEAKTAAQLCADLQSKERLKQEQADEirdekkglgrtielKKEILEKKQEELKFVIkelqqlEGSSDRILELDQELR 481

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1612 KEYEILLQSYENVSNEAERIQhvVEAVRQEKQELYGKLRSTEanKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILEL 1691
Cdd:TIGR00606  482 KAERELSKAEKNSLTETLKKE--VKSLQNEKADLDRKLRKLD--QEMEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSR 557

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1692 EEENDRLRAEVHPAGDTAKECMETLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQAN 1771
Cdd:TIGR00606  558 HSDELTSLLGYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLFDVCGSQDE 637

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1772 LEATEKHDNQTNVTEEGTQSIPGETEEQDSLsmstrptCSESVPSAKSANPAVSKDFSSHDEINNYlqqIDQLKERIAGL 1851
Cdd:TIGR00606  638 ESDLERLKEEIEKSSKQRAMLAGATAVYSQF-------ITQLTDENQSCCPVCQRVFQTEAELQEF---ISDLQSKLRLA 707

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1852 EEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAEEEKDDL--EERLMNQL 1929
Cdd:TIGR00606  708 PDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTImpEEESAKVC 787

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1930 AELNGSIGNYCQDVTDAQIKNELLESEMK--NLKKCVSELEEEKQQLVKEKTKVESEIR------KEYLEKIQGAQKEPG 2001
Cdd:TIGR00606  788 LTDVTIMERFQMELKDVERKIAQQAAKLQgsDLDRTVQQVNQEKQEKQHELDTVVSKIElnrkliQDQQEQIQHLKSKTN 867

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2002 N-KSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAElasfk 2080
Cdd:TIGR00606  868 ElKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDK----- 942

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2081 vlLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALrrEKVHLEETIGE 2160
Cdd:TIGR00606  943 --VNDIKEKVKNIHGYMKDIENKIQDGKDDYLKQKETELNTVNAQLEECEKHQEKINEDMRLMRQDI--DTQKIQERWLQ 1018

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2161 IQVTLNKKDKEVQQLQENLDSTVTQLAAF-TKSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEEI-----RLKEDNCSV 2234
Cdd:TIGR00606 1019 DNLTLRKRENELKEVEEELKQHLKEMGQMqVLQMKQEHQKLEENIDLIKRNHVLALGRQKGYEKEIkhfkkELREPQFRD 1098

                          970       980
                   ....*....|....*....|...
gi 1034632655 2235 LKDQLRQMSIHMEELKINISRLE 2257
Cdd:TIGR00606 1099 AEEKYREMMIVMRTTELVNKDLD 1121
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 2350-3008 3.66e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 53.15  E-value: 3.66e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2350 NSKFSYEQLETDLQaSRELTSRLHEEINMKEQKiisllsgkeEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEE 2429
Cdd:TIGR02169  208 EKAERYQALLKEKR-EYEGYELLKEKEALERQK---------EAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEEL 277

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2430 NKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSIILEKDQLIQEAAAENNKLKE 2509
Cdd:TIGR02169  278 NKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTE 357

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2510 EIRGLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDSQQKQLLEVQLQQNKELENKYAKLEEKLKESEEAnEDLRRSF 2589
Cdd:TIGR02169  358 EYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAI-AGIEAKI 436

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2590 NALQEEKQDLSKEIESLKVSISQLTRQVTALQEE-----GTLGLYHAQLKVKEEEVHRLSALFSSSQKR----------- 2653
Cdd:TIGR02169  437 NELEEEKEDKALEIKKQEWKLEQLAADLSKYEQElydlkEEYDRVEKELSKLQRELAEAEAQARASEERvrggraveevl 516

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2654 ----------IAEL------------------------EEELV---CVQKEAAKKVG----------------------- 2673
Cdd:TIGR02169  517 kasiqgvhgtVAQLgsvgeryataievaagnrlnnvvvEDDAVakeAIELLKRRKAGratflplnkmrderrdlsilsed 596

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2674 ----------EIEDKLKKELKHLHHDAGIMRNeTETAEE-----RVAELARDLVE----------MEQKLLMVTKENKG- 2727
Cdd:TIGR02169  597 gvigfavdlvEFDPKYEPAFKYVFGDTLVVED-IEAARRlmgkyRMVTLEGELFEksgamtggsrAPRGGILFSRSEPAe 675

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2728 ---LTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQL-KEQGLLNRERDALLSETafsmnsteENSLSHLE 2803
Cdd:TIGR02169  676 lqrLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIeKEIEQLEQEEEKLKERL--------EELEEDLS 747

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2804 KLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHlwnelEKFRKSEEGKQRSAAQPSTSPAEVQSLKKAMS 2883
Cdd:TIGR02169  748 SLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSH-----SRIPEIQAELSKLEEEVSRIEARLREIEQKLN 822

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2884 SLQNDRDRLLKELKNLQQQYL----QINQEITELHPLKAQLQEYQDKTKAFQIMQEELRQENLSWQHELHQLRMEKSSWE 2959
Cdd:TIGR02169  823 RLTLEKEYLEKEIQELQEQRIdlkeQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELE 902

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2960 IHERRMKEQY----------LMAISDKDQQLSHLQNLIRELRSSSSQTQPL-KVQYQRQA 3008
Cdd:TIGR02169  903 RKIEELEAQIekkrkrlselKAKLEALEEELSEIEDPKGEDEEIPEEELSLeDVQAELQR 962
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 151-1014 4.56e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 52.76  E-value: 4.56e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  151 HKLQEKEELISTLQAQLTQAQAEQpAQSSTEMEEFVmmkQQLQEKEEFISTLQAQLSQTQAEQAAQVVRE------KDAR 224
Cdd:TIGR02169  230 KEKEALERQKEAIERQLASLEEEL-EKLTEEISELE---KRLEEIEQLLEELNKKIKDLGEEEQLRVKEKigeleaEIAS 305

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  225 FETQVRLHEDELLQLVTQadvETEMQQKLRVLQRKLEEHEESLVGRAQVVDLLQQELTAAEQRNQILSQQLQQMEAEHNT 304
Cdd:TIGR02169  306 LERSIAEKERELEDAEER---LAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAE 382

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  305 LRNTVETEREESKILLEKMElevaerklsfhNLQEEMHHLLEQFEQAGQAQAELESRYSALEQKHKAEMEEKTSHILSLQ 384
Cdd:TIGR02169  383 TRDELKDYREKLEKLKREIN-----------ELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIK 451

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  385 KTGQELQSACDALKDQNSKLLQDKNEqavqsaqtIQQLEDQLQQKSKEISQFLNRLPLQQHETASQTSFPDVYNEGTQAV 464
Cdd:TIGR02169  452 KQEWKLEQLAADLSKYEQELYDLKEE--------YDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGV 523

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  465 ---TEENIASLQKRVVELENEKGAlllssiELEELKAENEKLSSQITLLEAQNRTGEAdrevSEISIVDIANKRSSSAEE 541
Cdd:TIGR02169  524 hgtVAQLGSVGERYATAIEVAAGN------RLNNVVVEDDAVAKEAIELLKRRKAGRA----TFLPLNKMRDERRDLSIL 593

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  542 SGQDVLEntfsqkhkeLSVLLLEMKEAQEEIAFLKLQLQG-KRAEEADHEVLDQKEMKQMEGEgiapikmkvFLEDTGqd 620
Cdd:TIGR02169  594 SEDGVIG---------FAVDLVEFDPKYEPAFKYVFGDTLvVEDIEAARRLMGKYRMVTLEGE---------LFEKSG-- 653

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  621 fpLMPNEESSLPAVEKEQASTEHQSRtseeislndagvELKSTKQDGDKSLSAVpdigqchQDELERLKSQILELELNFH 700
Cdd:TIGR02169  654 --AMTGGSRAPRGGILFSRSEPAELQ------------RLRERLEGLKRELSSL-------QSELRRIENRLDELSQELS 712

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  701 KAqeiyEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLSQVKEL-SMVTELRAQVKQLEMNLAEAERQR 779
Cdd:TIGR02169  713 DA----SRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELeARIEELEEDLHKLEEALNDLEARL 788

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  780 RLDYESQtahdnlLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSK 859
Cdd:TIGR02169  789 SHSRIPE------IQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGK 862

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  860 VEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNEekfsLGVEIKTLKEQLNLLSR 939
Cdd:TIGR02169  863 KEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSE----LKAKLEALEEELSEIED 938

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1034632655  940 AEEAKKEQVEED---NEVSSGLKQNYDEMSPAGQISKEELQhEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEE 1014
Cdd:TIGR02169  939 PKGEDEEIPEEElslEDVQAELQRVEEEIRALEPVNMLAIQ-EYEEVLKRLDELKEKRAKLEEERKAILERIEEYEKK 1015
PTZ00121 PTZ00121
MAEBL; Provisional
 939-1643 6.34e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 52.45  E-value: 6.34e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  939 RAEEAKK-EQVEEDNEVSSGLK-------QNYDEMSPAGQISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSR 1010
Cdd:PTZ00121  1177 KAEAARKaEEVRKAEELRKAEDarkaeaaRKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRK 1256

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1011 LEEELANLKDESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIYLKQTISEKEVELQHIRKDLEEKLAAEE-QF 1089
Cdd:PTZ00121  1257 FEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAaKK 1336

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1090 QALVKQMNQTLQDKTNQIDLLQAEISENQAIIQKLITSNtDASDGDSVALVKETVVISPPCTGSSEHWKPELEE--KILA 1167
Cdd:PTZ00121  1337 KAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEE-AKKKADAAKKKAEEKKKADEAKKKAEEDKKKADElkKAAA 1415

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1168 LEKEKEQLQKKLQEAltsRKAILKKAQEKERHLREELKQQKDDYNRLQEQfdEQSKENENIGDQLRQLQIQVRESIDGKL 1247
Cdd:PTZ00121  1416 AKKKADEAKKKAEEK---KKADEAKKKAEEAKKADEAKKKAEEAKKAEEA--KKKAEEAKKADEAKKKAEEAKKADEAKK 1490

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1248 PSTDQQESCSSTPGLEEPLFKATEQHHTQPVLESnlcpDWPSHSEDASALQGGTSVAQIKAQLKEIEAEKVElelkvsst 1327
Cdd:PTZ00121  1491 KAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKA----DEAKKAEEAKKADEAKKAEEKKKADELKKAEELK-------- 1558

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1328 TSELTKKSEEVFQLQEQINKQGLEIESLKTVshEAEVHAESLQQKLESSQLQIAGLEHLRELQPKLDELqklisKKEEDV 1407
Cdd:PTZ00121  1559 KAEEKKKAEEAKKAEEDKNMALRKAEEAKKA--EEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEEL-----KKAEEE 1631

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1408 SYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVELCEMKQKPEEIGEESRAKQQIQ--RKLQ 1485
Cdd:PTZ00121  1632 KKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEelKKKE 1711

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1486 AALISRKEALK------------------ENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRlaLLQEER 1547
Cdd:PTZ00121  1712 AEEKKKAEELKkaeeenkikaeeakkeaeEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEE--ELDEED 1789

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1548 DKLITEMDRSLLENQSLSSSCES----LKLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYEN 1623
Cdd:PTZ00121  1790 EKRRMEVDKKIKDIFDNFANIIEggkeGNLVINDSKEMEDSAIKEVADSKNMQLEEADAFEKHKFNKNNENGEDGNKEAD 1869

                          730       740
                   ....*....|....*....|
gi 1034632655 1624 VSNEAERIQHVVEAVRQEKQ 1643
Cdd:PTZ00121  1870 FNKEKDLKEDDEEEIEEADE 1889
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
199-378 6.87e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 52.22  E-value: 6.87e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  199 ISTLQAQLSQ-TQAEQAAQVVREKDARFEtQVRLHEDELLQLVTQADVETEM---------QQKLRVLQRKLEEHEESLV 268
Cdd:COG4913    227 ADALVEHFDDlERAHEALEDAREQIELLE-PIRELAERYAAARERLAELEYLraalrlwfaQRRLELLEAELEELRAELA 305

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  269 GRAQVVDLLQQELTAAEQ-----RNQILS---QQLQQMEAEHNTL---RNTVETEREESKILLEKMELEVAERKLSFHNL 337
Cdd:COG4913    306 RLEAELERLEARLDALREeldelEAQIRGnggDRLEQLEREIERLereLEERERRRARLEALLAALGLPLPASAEEFAAL 385

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*
gi 1034632655  338 QEEMHHLLEQFEQ----AGQAQAELESRYSALEQKHKAEMEEKTS 378
Cdd:COG4913    386 RAEAAALLEALEEeleaLEEALAEAEAALRDLRRELRELEAEIAS 430
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1389-1934 7.55e-06

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 52.04  E-value: 7.55e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1389 LQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQT--EIIEQ----------------EDLIKALHTQLEMQAKEHD 1450
Cdd:pfam15921  262 LQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSqlEIIQEqarnqnsmymrqlsdlESTVSQLRSELREAKRMYE 341

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1451 ERIKQLQ-------VELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEAL----KENKSLQEELSLARGTIERLTKSL 1519
Cdd:pfam15921  342 DKIEELEkqlvlanSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELslekEQNKRLWDRDTGNSITIDHLRREL 421

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1520 ADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAE 1599
Cdd:pfam15921  422 DDRNMEVQRLEALLKAMKSECQGQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDL 501

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1600 STEWQEKHK----------ELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQ---EA 1666
Cdd:pfam15921  502 TASLQEKERaieatnaeitKLRSRVDLKLQELQHLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQIENMTQlvgQH 581

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1667 EQEMEEMKEKMRKFAKSKQQKILELEE-------ENDRLRAEVHPAGDTAKECMEtLLSSNASMKEELERVKMEYETLSK 1739
Cdd:pfam15921  582 GRTAGAMQVEKAQLEKEINDRRLELQEfkilkdkKDAKIRELEARVSDLELEKVK-LVNAGSERLRAVKDIKQERDQLLN 660

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1740 KFQSLMSEKDSLSEEVQDLKHQIEGNvskqanleaTEKHDNQTNVTEEGTQSIPGETEEQDSLSMSTRPTCSESVPSAKS 1819
Cdd:pfam15921  661 EVKTSRNELNSLSEDYEVLKRNFRNK---------SEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMG 731

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1820 ANPAVSKDFSSHDEINNYLQQIDQL-----KERiAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMN 1894
Cdd:pfam15921  732 MQKQITAKRGQIDALQSKIQFLEEAmtnanKEK-HFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANME 810

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|
gi 1034632655 1895 LLNQQIQEELSRVTKLKETAEEEKDDLEERLMNQLAELNG 1934
Cdd:pfam15921  811 VALDKASLQFAECQDIIQRQEQESVRLKLQHTLDVKELQG 850
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 2495-2903 7.55e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 51.99  E-value: 7.55e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2495 QLIQEAAAENNKLKEEIRGLrshmDDLNSENAKLDAELIQYREDLNQVITIKDSQQKQLLEVQLQQNKELEnkyakleek 2574
Cdd:TIGR02169  146 DFISMSPVERRKIIDEIAGV----AEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAER--------- 212

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2575 lkeseeanedlrrsFNALQEEKQD-----LSKEIESLKVSISQLTRQVTALqeegtlglyhaqlkvkEEEVHRLSALFSS 2649
Cdd:TIGR02169  213 --------------YQALLKEKREyegyeLLKEKEALERQKEAIERQLASL----------------EEELEKLTEEISE 262

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2650 SQKRIAELEEELVCVQKEAAKKVGEIEDKLKKELKHLHhdagimrNETETAEERVAELARDLVEMEQKLLMVTKENKGLT 2729
Cdd:TIGR02169  263 LEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELE-------AEIASLERSIAEKERELEDAEERLAKLEAEIDKLL 335

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2730 AQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKEQGLLNRERDALLSETAfsmnsteENSLSHLEKLNQQL 2809
Cdd:TIGR02169  336 AEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKL-------EKLKREINELKREL 408

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2810 LSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKfrksEEGKQRSAAqpstspAEVQSLKKAMSSLQNDR 2889
Cdd:TIGR02169  409 DRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKK----QEWKLEQLA------ADLSKYEQELYDLKEEY 478

                          410
                   ....*....|....
gi 1034632655 2890 DRLLKELKNLQQQY 2903
Cdd:TIGR02169  479 DRVEKELSKLQREL 492
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 157-440 7.74e-06

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 52.26  E-value: 7.74e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  157 EELISTLQAQLTQAQAEQPAQSSTEMEefvmMKQQLQEKEEFISTLQAQLSQ-------TQAEQAAQVVREKDARFETQ- 228
Cdd:COG3096    835 EAELAALRQRRSELERELAQHRAQEQQ----LRQQLDQLKEQLQLLNKLLPQanlladeTLADRLEELREELDAAQEAQa 910

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  229 -VRLHEDELLQLVTQADVetemqqklrvLQRKLEEHEEslvgraqvvdlLQQELTAAEQRNQILSQQLQQME-----AEH 302
Cdd:COG3096    911 fIQQHGKALAQLEPLVAV----------LQSDPEQFEQ-----------LQADYLQAKEQQRRLKQQIFALSevvqrRPH 969

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  303 NTLRNTVETeREESKILLEKME--LEVAERKLSfhNLQEEMHHLLEQFEQAGQAQAELESRYSALEQKHKAEMEEKtshi 380
Cdd:COG3096    970 FSYEDAVGL-LGENSDLNEKLRarLEQAEEARR--EAREQLRQAQAQYSQYNQVLASLKSSRDAKQQTLQELEQEL---- 1042

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1034632655  381 lslqktgQELQSACDALKDQNSKLLQDK-NEQAVQSAQTIQQLEDQLQQKSKEISQFLNRL 440
Cdd:COG3096   1043 -------EELGVQADAEAEERARIRRDElHEELSQNRSRRSQLEKQLTRCEAEMDSLQKRL 1096
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 2109-2791 7.88e-06

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 52.04  E-value: 7.88e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2109 ESVKSQMKQKDEDLERRLEQAEEKHLKEK--------------KNMQEKLDAL----RREKVHLEETIGEIQVTLNKKDK 2170
Cdd:pfam15921   77 ERVLEEYSHQVKDLQRRLNESNELHEKQKfylrqsvidlqtklQEMQMERDAMadirRRESQSQEDLRNQLQNTVHELEA 156

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2171 EVQQLQENLDSTVTQLAAFTKSMSS----LQDDRDRVIDEAKKWERKFSDAIQSKEEEIRlkeDNCSVLKDQLRQMSIHM 2246
Cdd:pfam15921  157 AKCLKEDMLEDSNTQIEQLRKMMLShegvLQEIRSILVDFEEASGKKIYEHDSMSTMHFR---SLGSAISKILRELDTEI 233

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2247 EELKINISRLEHDKQIWESKAQTEVQL----QQKVCDTLQGENKELLSQLEETRHlyhSSQNELAKLESELKSLKDQLTD 2322
Cdd:pfam15921  234 SYLKGRIFPVEDQLEALKSESQNKIELllqqHQDRIEQLISEHEVEITGLTEKAS---SARSQANSIQSQLEIIQEQARN 310

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2323 lSNSLEKCkeQKGNLEGIIRQQEADIQNSKFSYEQLETDLQ-----ASRELTSRLHEEINMKE---------QKIISLLS 2388
Cdd:pfam15921  311 -QNSMYMR--QLSDLESTVSQLRSELREAKRMYEDKIEELEkqlvlANSELTEARTERDQFSQesgnlddqlQKLLADLH 387

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2389 GKEEAIQ-----------------VAIAELRQQHDK---EIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIK 2448
Cdd:pfam15921  388 KREKELSlekeqnkrlwdrdtgnsITIDHLRRELDDrnmEVQRLEALLKAMKSECQGQMERQMAAIQGKNESLEKVSSLT 467

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2449 KENIQQKAQLDSFVKSMSSLQ---NDRDRIVGDYQqleerhlSIILEKDQLIQEAAAENNKLK-------EEIRGLRSHM 2518
Cdd:pfam15921  468 AQLESTKEMLRKVVEELTAKKmtlESSERTVSDLT-------ASLQEKERAIEATNAEITKLRsrvdlklQELQHLKNEG 540

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2519 DDLNSENAKLDAELIQYREDlNQVITIKDSQQKQLLEVQLQQNKELenkyAKLEEKLKESEEANEDLRRSFNALQEEKQD 2598
Cdd:pfam15921  541 DHLRNVQTECEALKLQMAEK-DKVIEILRQQIENMTQLVGQHGRTA----GAMQVEKAQLEKEINDRRLELQEFKILKDK 615

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2599 LSKEIESLKVSISQLTRQVTALQEEGTLGLyHAQLKVKEEEVHRLSALfSSSQKRIAELEEELVCVQKEAAKKVGEIE-- 2676
Cdd:pfam15921  616 KDAKIRELEARVSDLELEKVKLVNAGSERL-RAVKDIKQERDQLLNEV-KTSRNELNSLSEDYEVLKRNFRNKSEEMEtt 693

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2677 -DKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEELDE 2755
Cdd:pfam15921  694 tNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNK 773

                          730       740       750
                   ....*....|....*....|....*....|....*.
gi 1034632655 2756 LKRKYDASLKELAQLKEQGLLNRERDALLSETAFSM 2791
Cdd:pfam15921  774 LSQELSTVATEKNKMAGELEVLRSQERRLKEKVANM 809
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 2292-3056 1.05e-05

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 51.66  E-value: 1.05e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2292 LEETRHLYHSSQ---NELAKLESELK-SLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRE 2367
Cdd:pfam15921   80 LEEYSHQVKDLQrrlNESNELHEKQKfYLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTVHELEAAKC 159

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2368 LTSRLHEEINMKEQKIISLLSGKE---EAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETl 2444
Cdd:pfam15921  160 LKEDMLEDSNTQIEQLRKMMLSHEgvlQEIRSILVDFEEASGKKIYEHDSMSTMHFRSLGSAISKILRELDTEISYLKG- 238

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2445 KTIKKENIQQKAQLDSFVKSMSSLQNDRDRIvgdyQQLEERHLSIILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNS- 2523
Cdd:pfam15921  239 RIFPVEDQLEALKSESQNKIELLLQQHQDRI----EQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQARNQNSm 314

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2524 ---ENAKLDAELIQYREDLNQVITIKDSQQKQLLEVQLQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLS 2600
Cdd:pfam15921  315 ymrQLSDLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELS 394

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2601 KEIESLKVSISQLTRQVTalqeegTLGLYHAQLKVKEEEVHRLSALFSSSQKRI-AELEEELVCVQ--KEAAKKVGEIED 2677
Cdd:pfam15921  395 LEKEQNKRLWDRDTGNSI------TIDHLRRELDDRNMEVQRLEALLKAMKSECqGQMERQMAAIQgkNESLEKVSSLTA 468

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2678 KLkkelkhlhhdagimrnetETAEERVAELARDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSSlqnsrdhANEELDELK 2757
Cdd:pfam15921  469 QL------------------ESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEA-------TNAEITKLR 523

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2758 RKYDASLKELAQLKEQGllnrerDALlsetafsmnsteENSLSHLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAM 2837
Cdd:pfam15921  524 SRVDLKLQELQHLKNEG------DHL------------RNVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRTA 585

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2838 ASLQNERDHLWNELE---------KFRKSEEGKQRSAAQPSTSPAEVQSLK---------KAMSSLQNDRDRLLKELKNL 2899
Cdd:pfam15921  586 GAMQVEKAQLEKEINdrrlelqefKILKDKKDAKIRELEARVSDLELEKVKlvnagserlRAVKDIKQERDQLLNEVKTS 665

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2900 QQQYLQINQEITELHplkaqlQEYQDKTKAFQIMQEELRQENLSWQHELHQLRMEKSSWE---IHERRMKEQYLMAISDK 2976
Cdd:pfam15921  666 RNELNSLSEDYEVLK------RNFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEgsdGHAMKVAMGMQKQITAK 739

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2977 DQQLSHLQNLIR---ELRSSSSQTQPLKVQYQRQASPETSASPDGSQNLVYETELLRTQLNDSLKEIHQKELRIQQLNSN 3053
Cdd:pfam15921  740 RGQIDALQSKIQfleEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMEVALDKASLQ 819


                   ...
gi 1034632655 3054 FSQ 3056
Cdd:pfam15921  820 FAE 822
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 236-452 1.11e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 50.53  E-value: 1.11e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  236 LLQLVTQADVETEMQQKLRVLQRKLEEHEESLVGRAQVVDLLQQELTAAEQRNQILSQQLQQMEAEHNTLR---NTVETE 312
Cdd:COG4942     12 ALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEaelAELEKE 91

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  313 REESKILLEKMELEVAE--RKLSFHNLQEEMHHLL-----EQFEQAGQAQAELESRYSALEQKHKAEMEEKTSHILSLQK 385
Cdd:COG4942     92 IAELRAELEAQKEELAEllRALYRLGRQPPLALLLspedfLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEA 171

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1034632655  386 TGQELQSACDALKDQNSKLLQDKNEQAVQSAQTIQQLE------DQLQQKSKEISQFLNRLPLQQHETASQTS 452
Cdd:COG4942    172 ERAELEALLAELEEERAALEALKAERQKLLARLEKELAelaaelAELQQEAEELEALIARLEAEAAAAAERTP 244
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1301-1459 1.17e-05

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 49.54  E-value: 1.17e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1301 TSVAQIKAQLKEIEAEKVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLktvsheaevhaESLQQKLESSQLQI 1380
Cdd:COG1579     17 SELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEV-----------EARIKKYEEQLGNV 85

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1034632655 1381 AGLEHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVE 1459
Cdd:COG1579     86 RNNKEYEALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAE 164
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
701-906 1.27e-05

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 51.17  E-value: 1.27e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  701 KAQEIYEKNLDEKAKEISNLNQLIEEFKKNADnnssaFTALSEERDQLLSQVKEL-SMVTELRAQVKQLEMNLAEAERQr 779
Cdd:COG3206    175 KALEFLEEQLPELRKELEEAEAALEEFRQKNG-----LVDLSEEAKLLLQQLSELeSQLAEARAELAEAEARLAALRAQ- 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  780 rLDYESQTAHDNLLTEQIHSLSIEakskdvkIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRH---- 855
Cdd:COG3206    249 -LGSGPDALPELLQSPVIQQLRAQ-------LAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQRILAslea 320

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1034632655  856 ----ISSKVEELSQALSQKELEITKMDQL---LLEKKRDVETLQQTIEEKDQQVTEIS 906
Cdd:COG3206    321 eleaLQAREASLQAQLAQLEARLAELPELeaeLRRLEREVEVARELYESLLQRLEEAR 378
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 2390-3099 1.27e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 51.22  E-value: 1.27e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2390 KEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDsfvKSMSSLQ 2469
Cdd:TIGR02169  185 NIERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAIERQLASLEEELE---KLTEEIS 261

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2470 NDRDRIVGDYQQLEERHLSIILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDSQ 2549
Cdd:TIGR02169  262 ELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEEL 341

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2550 QKQLLEVQLQQNK------ELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSKEIESLKVSISQLtrQVTALQEE 2623
Cdd:TIGR02169  342 EREIEEERKRRDKlteeyaELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRL--QEELQRLS 419

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2624 GTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELvcvqKEAAKKVGEIEDKLKKelkhlhhdagiMRNETETAEER 2703
Cdd:TIGR02169  420 EELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKL----EQLAADLSKYEQELYD-----------LKEEYDRVEKE 484

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2704 VAELARDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSSLQNSRdhanEELDELKRKYDASLkELAQLKEQGLLNRERDAL 2783
Cdd:TIGR02169  485 LSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTV----AQLGSVGERYATAI-EVAAGNRLNNVVVEDDAV 559

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2784 LSETAFSMNSTEENSLSHLEKLNQQLLSKDEQLLHLSSQLEDSYNQV---QSFSKA----------MASLQNERDHLWN- 2849
Cdd:TIGR02169  560 AKEAIELLKRRKAGRATFLPLNKMRDERRDLSILSEDGVIGFAVDLVefdPKYEPAfkyvfgdtlvVEDIEAARRLMGKy 639

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2850 -----ELEKFRKS------EEGKQRSAAQPSTSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELH---- 2914
Cdd:TIGR02169  640 rmvtlEGELFEKSgamtggSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASrkig 719

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2915 PLKAQLQEYQDKTKAFQIMQEELRQENLSWQHELHQLR--MEKSSWEIHERRMK-EQYLMAISDKDQQLSH--------- 2982
Cdd:TIGR02169  720 EIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKseLKELEARIEELEEDlHKLEEALNDLEARLSHsripeiqae 799

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2983 LQNLIRELRSSSSQTQPLKVQYQRQASPETSASpDGSQNLVYETELLRTQLNDSLKEIHQKELRIQQLNSNFSQLLEEKN 3062
Cdd:TIGR02169  800 LSKLEEEVSRIEARLREIEQKLNRLTLEKEYLE-KEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALR 878

                          730       740       750
                   ....*....|....*....|....*....|....*..
gi 1034632655 3063 TLSIQLCDTSQSLRENQQHYGDLLNHCAVLEKQVQEL 3099
Cdd:TIGR02169  879 DLESRLGDLKKERDELEAQLRELERKIEELEAQIEKK 915
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 1582-2910 1.87e-05

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 50.82  E-value: 1.87e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1582 KEKLVKEIESLKSSKIAESTEWQEKHKELQKEYE-------ILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTeA 1654
Cdd:TIGR01612  535 KAKLYKEIEAGLKESYELAKNWKKLIHEIKKELEeenedsiHLEKEIKDLFDKYLEIDDEIIYINKLKLELKEKIKNI-S 613

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1655 NKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRaevhpagdtakecmetllssnASMKEELERV-KME 1733
Cdd:TIGR01612  614 DKNEYIKKAIDLKKIIENNNAYIDELAKISPYQVPEHLKNKDKIY---------------------STIKSELSKIyEDD 672

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1734 YETLSKKFQSLMSEKDSLSEE----VQDLKHQIEGNVSKQANLEATEKHDNQTNVTEEGTQSIPGETEEQDSLSMSTRPT 1809
Cdd:TIGR01612  673 IDALYNELSSIVKENAIDNTEdkakLDDLKSKIDKEYDKIQNMETATVELHLSNIENKKNELLDIIVEIKKHIHGEINKD 752

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1810 CSESVPSAKSANPAVSKDFSSH----DEINNYLQQIDQLKERIAG-LEEEKQKNKEFSQTLENEKNtLLSQISTKDGELK 1884
Cdd:TIGR01612  753 LNKILEDFKNKEKELSNKINDYakekDELNKYKSKISEIKNHYNDqINIDNIKDEDAKQNYDKSKE-YIKTISIKEDEIF 831

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1885 MLQEEVTKMNllnqqiQEELSRVTKLKETAEEEKDDLEERlMNQLAELNGSIGNycqdvtdaQIKNELLESEMKNLKKCV 1964
Cdd:TIGR01612  832 KIINEMKFMK------DDFLNKVDKFINFENNCKEKIDSE-HEQFAELTNKIKA--------EISDDKLNDYEKKFNDSK 896

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1965 SELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKE--LQELLKEKQQEVKQLQKDCIRYQ--------EKI 2034
Cdd:TIGR01612  897 SLINEINKSIEEEYQNINTLKKVDEYIKICENTKESIEKFHNKQniLKEILNKNIDTIKESNLIEKSYKdkfdntliDKI 976

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2035 SALERTVKALEFVQTESQKDLEIT-----KENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLKL--KKELQSN 2107
Cdd:TIGR01612  977 NELDKAFKDASLNDYEAKNNELIKyfndlKANLGKNKENMLYHQFDEKEKATNDIEQKIEDANKNIPNIEIaiHTSIYNI 1056

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2108 KESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIgeiqvtlnKKDKEVQQLQENLDSTVTQLA 2187
Cdd:TIGR01612 1057 IDEIEKEIGKNIELLNKEILEEAEINITNFNEIKEKLKHYNFDDFGKEENI--------KYADEINKIKDDIKNLDQKID 1128

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2188 AFTKSMSSLQDDRDRVIDEAK----KWERKFSDAIQSKE-EEIRLKEDNCSVLKDQLRQMSIHMEELKINISRLEHDKQI 2262
Cdd:TIGR01612 1129 HHIKALEEIKKKSENYIDEIKaqinDLEDVADKAISNDDpEEIEKKIENIVTKIDKKKNIYDEIKKLLNEIAEIEKDKTS 1208

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2263 WESKAQTEVQLQQKVcdtlqgeNKELLSQLEEtrhlyhssqnELAKLESELKSLKDQLTDLSNSLEKCKEQKgNLEGIIR 2342
Cdd:TIGR01612 1209 LEEVKGINLSYGKNL-------GKLFLEKIDE----------EKKKSEHMIKAMEAYIEDLDEIKEKSPEIE-NEMGIEM 1270

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2343 QQEADIQNSKFSYEQLETDLQASRELTSRLhEEINMKEQKIISLLSGK------EEAIQVAIAElRQQHDKEIKELENLL 2416
Cdd:TIGR01612 1271 DIKAEMETFNISHDDDKDHHIISKKHDENI-SDIREKSLKIIEDFSEEsdindiKKELQKNLLD-AQKHNSDINLYLNEI 1348

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2417 SQEEEENIVLEEEN--KKAVDKTNQLMETLKTIKKEnIQQKAQLDSFVKSMSSLQNDRDRIVG--DYQQLEERHLSIILE 2492
Cdd:TIGR01612 1349 ANIYNILKLNKIKKiiDEVKEYTKEIEENNKNIKDE-LDKSEKLIKKIKDDINLEECKSKIEStlDDKDIDECIKKIKEL 1427

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2493 KDQLIQEAAAENNKLKEEirglrshmdDLNSENAKLDAELIQYREDLNQ-VITIKDSQQKQLLEV---QLQQNKELENKY 2568
Cdd:TIGR01612 1428 KNHILSEESNIDTYFKNA---------DENNENVLLLFKNIEMADNKSQhILKIKKDNATNDHDFninELKEHIDKSKGC 1498

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2569 AKLEEKLKESEEANEDLRRSFNalQEEKQDLSKEIE-SLKVSISQLTRQVTALQEEgtLGLYHAQLKVKEEevhrlsalf 2647
Cdd:TIGR01612 1499 KDEADKNAKAIEKNKELFEQYK--KDVTELLNKYSAlAIKNKFAKTKKDSEIIIKE--IKDAHKKFILEAE--------- 1565

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2648 sSSQKRIAELEEELVCVQKEAAK-------------KVGEIEDKLKKeLKHLHHDAGIMRNETETAEERVAELARDLVEM 2714
Cdd:TIGR01612 1566 -KSEQKIKEIKKEKFRIEDDAAKndksnkaaidiqlSLENFENKFLK-ISDIKKKINDCLKETESIEKKISSFSIDSQDT 1643

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2715 EqkllmvTKENKGLTAQIQSFGRSMSSLQNSRDHANEELDEL--------------KRKYDASLKElaQLKEQGLLNRER 2780
Cdd:TIGR01612 1644 E------LKENGDNLNSLQEFLESLKDQKKNIEDKKKELDELdseiekieidvdqhKKNYEIGIIE--KIKEIAIANKEE 1715

                         1290      1300      1310      1320      1330      1340      1350      1360
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2781 dalLSETAFSMNSTEENSLSHLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMAS--------------LQNERDH 2846
Cdd:TIGR01612 1716 ---IESIKELIEPTIENLISSFNTNDLEGIDPNEKLEEYNTEIGDIYEEFIELYNIIAGcletvskepitydeIKNTRIN 1792

                         1370      1380      1390      1400      1410      1420
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1034632655 2847 LWNELEKFRKSEegKQRSAAQPSTSPAEVQSLKKAM-SSLQNDRDRLLKELKNLQQQYLQINQEI 2910
Cdd:TIGR01612 1793 AQNEFLKIIEIE--KKSKSYLDDIEAKEFDRIINHFkKKLDHVNDKFTKEYSKINEGFDDISKSI 1855
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 992-1869 1.88e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 50.84  E-value: 1.88e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  992 RKLQAALinrkELLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKE-NKEYSEKCVTSKCQEIEIYLKQT------ 1064
Cdd:TIGR02169  170 RKKEKAL----EELEEVEENIERLDLIIDEKRQQLERLRREREKAERYQAlLKEKREYEGYELLKEKEALERQKeaierq 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1065 ISEKEVELQHIRKDLEEKLAAEEQFQALVKQMNQTLQDKT-NQIDLLQAEISENQAIIQKLITSNTDASDgdSVALVKET 1143
Cdd:TIGR02169  246 LASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGeEEQLRVKEKIGELEAEIASLERSIAEKER--ELEDAEER 323

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1144 VVISPPCTGSSEHWKPELEEKILALEKEKEQLQKKLQEALTSRKAILKKAQEKE---RHLREELKQQKDDYNRLQEQFDE 1220
Cdd:TIGR02169  324 LAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDkefAETRDELKDYREKLEKLKREINE 403

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1221 QSKENENIGDQLRQLQIQVREsIDGKLPSTDQQ--ESCSSTPGLEEPLFKATEQHHTQPVLESNLCPDWPSHSEDASALQ 1298
Cdd:TIGR02169  404 LKRELDRLQEELQRLSEELAD-LNAAIAGIEAKinELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVE 482

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1299 GGTSVAQIKAQLKEIEAEKVELELKVSSTTSELTKKSEE-----VFQLQEQINKQGLEIES-----LKTVSHEAEVHAES 1368
Cdd:TIGR02169  483 KELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQgvhgtVAQLGSVGERYATAIEVaagnrLNNVVVEDDAVAKE 562

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1369 LQQKLESSQLQIAGLEHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKI---QTEIIEQEDLIKALHTQLEMQ 1445
Cdd:TIGR02169  563 AIELLKRRKAGRATFLPLNKMRDERRDLSILSEDGVIGFAVDLVEFDPKYEPAFKYvfgDTLVVEDIEAARRLMGKYRMV 642

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1446 AKEHDERIK---------QLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLT 1516
Cdd:TIGR02169  643 TLEGELFEKsgamtggsrAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIE 722

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1517 KSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMDRsllenqslssscesLKLALEGLTEDKEKLVKEIESLKSSK 1596
Cdd:TIGR02169  723 KEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKE--------------LEARIEELEEDLHKLEEALNDLEARL 788

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1597 IAEstEWQEKHKELQKEYEIlLQSYENVSNEAERI----QHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAeqemee 1672
Cdd:TIGR02169  789 SHS--RIPEIQAELSKLEEE-VSRIEARLREIEQKlnrlTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENL------ 859

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1673 mkekmrkfakskQQKILELEEENDRLRAEVhpagdtakecmETLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLS 1752
Cdd:TIGR02169  860 ------------NGKKEELEEELEELEAAL-----------RDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKR 916

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1753 EEVQDLKHQIEGNVSKQANLEATEKHDnqtnvteegtQSIPGETEEQDSLSMsTRPTCSESVPSAKSANpavskdFSSHD 1832
Cdd:TIGR02169  917 KRLSELKAKLEALEEELSEIEDPKGED----------EEIPEEELSLEDVQA-ELQRVEEEIRALEPVN------MLAIQ 979

                          890       900       910
                   ....*....|....*....|....*....|....*..
gi 1034632655 1833 EINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEK 1869
Cdd:TIGR02169  980 EYEEVLKRLDELKEKRAKLEEERKAILERIEEYEKKK 1016
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 1830-2532 1.94e-05

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 50.61  E-value: 1.94e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1830 SHDEINNYLQQIDQlkerIAGLEEEKQKnkefSQTLENEKNTLLSQIStkdgELKMLQEEVTKMNLlnqQIQEELSRVTK 1909
Cdd:pfam12128  219 NRQQVEHWIRDIQA----IAGIMKIRPE----FTKLQQEFNTLESAEL----RLSHLHFGYKSDET---LIASRQEERQE 283

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1910 LKETAEEEKDDLEERLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKcvSELEEEKQQLVKEKTkVESEIrkEY 1989
Cdd:pfam12128  284 TSAELNQLLRTLDDQWKEKRDELNGELSAADAAVAKDRSELEALEDQHGAFLD--ADIETAAADQEQLPS-WQSEL--EN 358

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1990 LEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQL----QKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQA 2065
Cdd:pfam12128  359 LEERLKALTGKHQDVTAKYNRRRSKIKEQNNRDIagikDKLAKIREARDRQLAVAEDDLQALESELREQLEAGKLEFNEE 438

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2066 VEHRKKAQAELasfKVLLDDTQSEaarvladnlklkKELQSNKESVKSQMKQKDEDLERR---LEQAEEKHLKEKKNMQE 2142
Cdd:pfam12128  439 EYRLKSRLGEL---KLRLNQATAT------------PELLLQLENFDERIERAREEQEAAnaeVERLQSELRQARKRRDQ 503

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2143 KLDALRREKVHLEETIGEIqvtlnkkdkevQQLQENLDSTVTQLAAFTKSMSSL-QDDRDRVIDEAKKWErkfSDAIQSK 2221
Cdd:pfam12128  504 ASEALRQASRRLEERQSAL-----------DELELQLFPQAGTLLHFLRKEAPDwEQSIGKVISPELLHR---TDLDPEV 569

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2222 EEEIRLKEDNCSVLKDQLRQMSI-----HMEELKINISRLEHDKQiwesKAQTEVQLQQKVCDTLQGENKELLSQLEETR 2296
Cdd:pfam12128  570 WDGSVGGELNLYGVKLDLKRIDVpewaaSEEELRERLDKAEEALQ----SAREKQAAAEEQLVQANGELEKASREETFAR 645

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2297 HLYHSSQNELAKLESELKSLKDQLTD-LSNSLEKCKEQKGNLEGIIRQQEADIQNSkfsyeqletdLQASRELTSRLHEE 2375
Cdd:pfam12128  646 TALKNARLDLRRLFDEKQSEKDKKNKaLAERKDSANERLNSLEAQLKQLDKKHQAW----------LEEQKEQKREARTE 715

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2376 INMKEQKIISLLSGKEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKeNIQQK 2455
Cdd:pfam12128  716 KQAYWQVVEGALDAQLALLKAAIAARRSGAKAELKALETWYKRDLASLGVDPDVIAKLKREIRTLERKIERIAV-RRQEV 794

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1034632655 2456 AQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSIILEKdqLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAEL 2532
Cdd:pfam12128  795 LRYFDWYQETWLQRRPRLATQLSNIERAISELQQQLAR--LIADTKLRRAKLEMERKASEKQQVRLSENLRGLRCEM 869
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
2348-2903 2.04e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 50.45  E-value: 2.04e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2348 IQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKI--ISLLSGKEEAIQVAIAELRQQHdKEIKELENLLSQEEEENIV 2425
Cdd:PRK03918   171 IKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLreINEISSELPELREELEKLEKEV-KELEELKEEIEELEKELES 249

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2426 LEEENKKAVDKTNQLMETLKTIKKEniqqKAQLDSFVKSMSSLQNDRDRivgdYQQLEERHLSIILEKDQLIQEAAaenn 2505
Cdd:PRK03918   250 LEGSKRKLEEKIRELEERIEELKKE----IEELEEKVKELKELKEKAEE----YIKLSEFYEEYLDELREIEKRLS---- 317

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2506 KLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDSQQK----QLLEVQLQQNKELENKYAKL--EEKLKESE 2579
Cdd:PRK03918   318 RLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELyeeaKAKKEELERLKKRLTGLTPEklEKELEELE 397

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2580 EANEDLRRSFNALQEEKQDLSKEIESLKVSISQLT----------RQVTALQEEGTLGLYHAQLKVKEEEVHRLSALFSS 2649
Cdd:PRK03918   398 KAKEEIEEEISKITARIGELKKEIKELKKAIEELKkakgkcpvcgRELTEEHRKELLEEYTAELKRIEKELKEIEEKERK 477

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2650 SQKRIAELEEEL-----VCVQKEAAKKVGEIEDKLKK-----------ELKHLHHDAGIMRNETETAE---ERVAELARD 2710
Cdd:PRK03918   478 LRKELRELEKVLkkeseLIKLKELAEQLKELEEKLKKynleelekkaeEYEKLKEKLIKLKGEIKSLKkelEKLEELKKK 557

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2711 LVEMEQKLLMVTKENKGLTAQIQSFGRSmsslqnSRDHANEELDELKRKYDA--SLKELAQLKEQGLLNRERDALLSETA 2788
Cdd:PRK03918   558 LAELEKKLDELEEELAELLKELEELGFE------SVEELEERLKELEPFYNEylELKDAEKELEREEKELKKLEEELDKA 631

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2789 FSMNSTEENSLSHLEKLNQQLLSKDEQLLHlssqlEDSYNQVQSFSKAMASLQNERDHLWNELEKFRKSEEGKQRSAAQP 2868
Cdd:PRK03918   632 FEELAETEKRLEELRKELEELEKKYSEEEY-----EELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEER 706

                          570       580       590
                   ....*....|....*....|....*....|....*
gi 1034632655 2869 STSPAEVQSLKKAMSSLQNDRDRlLKELKNLQQQY 2903
Cdd:PRK03918   707 EKAKKELEKLEKALERVEELREK-VKKYKALLKER 740
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1575-2181 2.18e-05

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 50.40  E-value: 2.18e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1575 LEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEIL---LQSYENVSNEAERIQHVVEAVRQEKQELYGKLRS 1651
Cdd:TIGR04523   98 INKLNSDLSKINSEIKNDKEQKNKLEVELNKLEKQKKENKKNIdkfLTEIKKKEKELEKLNNKYNDLKKQKEELENELNL 177

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1652 TEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQ------KILELEEENDRLRAEVHPAGD----------TAKECMET 1715
Cdd:TIGR04523  178 LEKEKLNIQKNIDKIKNKLLKLELLLSNLKKKIQKnkslesQISELKKQNNQLKDNIEKKQQeinektteisNTQTQLNQ 257

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1716 LLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQANLEATEKHDNQTNVTEEGTQSIPGE 1795
Cdd:TIGR04523  258 LKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEQDWNKELKSELKNQEKKLEEIQNQISQNNKII 337

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1796 TEEQDSLSmstrptcsesvpsaksanpAVSKDFSSHDEINNYLQ-QIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLS 1874
Cdd:TIGR04523  338 SQLNEQIS-------------------QLKKELTNSESENSEKQrELEEKQNEIEKLKKENQSYKQEIKNLESQINDLES 398

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1875 QISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAEEEKDDLEerlmNQLAELNGSIGNYCQDVTDAQIKNELLE 1954
Cdd:TIGR04523  399 KIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLT----NQDSVKELIIKNLDNTRESLETQLKVLS 474

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1955 SEMKNLKkcvSELEEEKQQLVKEktkvESEIRKEYLEKIQGAQKepgnkshAKELQELLKEKQQEVKQLQKDCIRYQEKI 2034
Cdd:TIGR04523  475 RSINKIK---QNLEQKQKELKSK----EKELKKLNEEKKELEEK-------VKDLTKKISSLKEKIEKLESEKKEKESKI 540

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2035 SALERTVKALEFvqtesqkdlEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQ 2114
Cdd:TIGR04523  541 SDLEDELNKDDF---------ELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKK 611

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1034632655 2115 MKQKDEDLErRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQENLDS 2181
Cdd:TIGR04523  612 ISSLEKELE-KAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKEIRNKWPEIIKKIKESKTKIDD 677
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1163-1392 2.72e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 49.38  E-value: 2.72e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1163 EKILALEKEKEQLQKKLQEAltsrKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVREs 1242
Cdd:COG4942     20 DAAAEAEAELEQLQQEIAEL----EKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAE- 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1243 idgklpstdQQESCSSTPGLEEPLFKATEQHHTQPVLESNLCPDWPSHSEDASALQGGTS------VAQIKAQLKEIEAE 1316
Cdd:COG4942     95 ---------LRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAparreqAEELRADLAELAAL 165

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1034632655 1317 KVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLEHLRELQPK 1392
Cdd:COG4942    166 RAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAE 241
46 PHA02562
endonuclease subunit; Provisional
 1832-1992 3.13e-05

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 49.63  E-value: 3.13e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1832 DEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMNLLnQQIQEELSRVTKLK 1911
Cdd:PHA02562   227 EEAKTIKAEIEELTDELLNLVMDIEDPSAALNKLNTAAAKIKSKIEQFQKVIKMYEKGGVCPTCT-QQISEGPDRITKIK 305

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1912 E---------TAEEEKDDLEERLMNQLA-------ELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLV 1975
Cdd:PHA02562   306 DklkelqhslEKLDTAIDELEEIMDEFNeqskkllELKNKISTNKQSLITLVDKAKKVKAAIEELQAEFVDNAEELAKLQ 385

                          170
                   ....*....|....*..
gi 1034632655 1976 KEKTKVESEIRKEYLEK 1992
Cdd:PHA02562   386 DELDKIVKTKSELVKEK 402
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
2237-2853 4.03e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 49.53  E-value: 4.03e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2237 DQLRQMSIHMEELKINISRLEHDKQIWES--KAQTEVQLQQKVCDTLQGENKELLSQLEETRHlyHSSQNELAKLESELK 2314
Cdd:COG4913    235 DDLERAHEALEDAREQIELLEPIRELAERyaAARERLAELEYLRAALRLWFAQRRLELLEAEL--EELRAELARLEAELE 312

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2315 SLKDQLTDLSNSLEKCKEQKGNLEGIIRQQ-EADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKIisllsgkeEA 2393
Cdd:COG4913    313 RLEARLDALREELDELEAQIRGNGGDRLEQlEREIERLERELEERERRRARLEALLAALGLPLPASAEEF--------AA 384

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2394 IQVAIAELRQQHDKEIKELENLLSQEEEENivleeenKKAVDKTNQLMETLKTIKkeniQQKAQLDSFVKSM-----SSL 2468
Cdd:COG4913    385 LRAEAAALLEALEEELEALEEALAEAEAAL-------RDLRRELRELEAEIASLE----RRKSNIPARLLALrdalaEAL 453

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2469 QNDRD--RIVGDYQQLEERH---------------LSIILEKDQLIQEAAA-ENNKLKEEIRGLRSHMDDLNSENAKLDA 2530
Cdd:COG4913    454 GLDEAelPFVGELIEVRPEEerwrgaiervlggfaLTLLVPPEHYAAALRWvNRLHLRGRLVYERVRTGLPDPERPRLDP 533

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2531 EliqyreDLNQVITIKDSQQKQLLEVQLQqnkelenkyakleeklkeseeanedlrRSFNALQEEkqdlskeieslkvSI 2610
Cdd:COG4913    534 D------SLAGKLDFKPHPFRAWLEAELG---------------------------RRFDYVCVD-------------SP 567

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2611 SQLTRQVTALQEEGTL-GLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELVCVQKEAAKkVGEIEDKLKKELKHLH-- 2687
Cdd:COG4913    568 EELRRHPRAITRAGQVkGNGTRHEKDDRRRIRSRYVLGFDNRAKLAALEAELAELEEELAE-AEERLEALEAELDALQer 646

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2688 HDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKGLTAqiqsfgrsmssLQNSRDHANEELDELKRKYDASLKEL 2767
Cdd:COG4913    647 REALQRLAEYSWDEIDVASAEREIAELEAELERLDASSDDLAA-----------LEEQLEELEAELEELEEELDELKGEI 715

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2768 AQL-KEQGLLNRERDALLSETAFSMNSTEENSLSHLEKLNQQLLsKDEQLLHLSSQLEDSYnqvqsfskamASLQNERDH 2846
Cdd:COG4913    716 GRLeKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAAL-GDAVERELRENLEERI----------DALRARLNR 784


                   ....*..
gi 1034632655 2847 LWNELEK 2853
Cdd:COG4913    785 AEEELER 791
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1307-1515 4.32e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 49.53  E-value: 4.32e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1307 KAQLKEIEAEKVELELKVSsttsELTKKSEEVFQLQEQINKQGLEIESLKTVShEAEVHAESLQQKLESSQLQiagLEHL 1386
Cdd:COG4913    609 RAKLAALEAELAELEEELA----EAEERLEALEAELDALQERREALQRLAEYS-WDEIDVASAEREIAELEAE---LERL 680

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1387 RELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEmqakEHDERIKQLQVELCEmKQK 1466
Cdd:COG4913    681 DASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLE----AAEDLARLELRALLE-ERF 755

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*....
gi 1034632655 1467 PEEIGEESRakQQIQRKLQAALisrkealkenKSLQEELSLARGTIERL 1515
Cdd:COG4913    756 AAALGDAVE--RELRENLEERI----------DALRARLNRAEEELERA 792
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1830-2347 4.58e-05

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 49.35  E-value: 4.58e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1830 SHDEINNYLQQ-IDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQistkdgeLKMLQEEVTKMN-LLNQQIQEELSRV 1907
Cdd:pfam15921  254 SQNKIELLLQQhQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQ-------LEIIQEQARNQNsMYMRQLSDLESTV 326

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1908 TKLKETAEEEKDDLEERLmnqlAELNGSIGNYCQDVTDAQIKNELLESEMKNLkkcvselEEEKQQLVKEKTKVESEIRK 1987
Cdd:pfam15921  327 SQLRSELREAKRMYEDKI----EELEKQLVLANSELTEARTERDQFSQESGNL-------DDQLQKLLADLHKREKELSL 395

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1988 EYLEKIQGAQKEPGNKSHAKELQELLKEKQQEV-------KQLQKDCI-RYQEKISALERTVKALEFVQTESQKdLEITK 2059
Cdd:pfam15921  396 EKEQNKRLWDRDTGNSITIDHLRRELDDRNMEVqrleallKAMKSECQgQMERQMAAIQGKNESLEKVSSLTAQ-LESTK 474

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2060 ENLAQAVEHRKKAQAELASFKVLLDD--------------TQSEAARVLAD-NLKLK------------KELQSNKESVK 2112
Cdd:pfam15921  475 EMLRKVVEELTAKKMTLESSERTVSDltaslqekeraieaTNAEITKLRSRvDLKLQelqhlknegdhlRNVQTECEALK 554

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2113 SQMKQKDEDLERrLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNK----KDKEVQQLQEnLDSTVTQLAA 2188
Cdd:pfam15921  555 LQMAEKDKVIEI-LRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEfkilKDKKDAKIRE-LEARVSDLEL 632

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2189 FTKSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEEIRLKEDNCSVLKDQLRQMSIHME--------ELKINISRLEHDK 2260
Cdd:pfam15921  633 EKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMEtttnklkmQLKSAQSELEQTR 712

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2261 QIWESKA-------------QTEVQLQQKVCDTLQGENK---ELLSQLEETRHLYHSSQNELAK---------------- 2308
Cdd:pfam15921  713 NTLKSMEgsdghamkvamgmQKQITAKRGQIDALQSKIQfleEAMTNANKEKHFLKEEKNKLSQelstvateknkmagel 792

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|.
gi 1034632655 2309 --LESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEAD 2347
Cdd:pfam15921  793 evLRSQERRLKEKVANMEVALDKASLQFAECQDIIQRQEQE 833
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 1823-2061 5.66e-05

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 49.45  E-value: 5.66e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1823 AVSKDFSSHDEINNYLQQIDQLKERIAgleeEKQKNKEFSQTLENEKNTLLSQISTKDGELkmlqeEVTKMNLLNQQIQE 1902
Cdd:NF012221  1536 ATSESSQQADAVSKHAKQDDAAQNALA----DKERAEADRQRLEQEKQQQLAAISGSQSQL-----ESTDQNALETNGQA 1606

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1903 ELSRVTKLKETAEEEKDDLEERL--MNQLAELNGSIGN-YCQDVTDAQIKNelLESEMKNLKKCVSE-LEEEKQQLVKEK 1978
Cdd:NF012221  1607 QRDAILEESRAVTKELTTLAQGLdaLDSQATYAGESGDqWRNPFAGGLLDR--VQEQLDDAKKISGKqLADAKQRHVDNQ 1684

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1979 TKVESEIRKEYLEKIQGAQKEPG-------NKSHAKELQELLKEKQQEVKQLQKDC-IRYQEKISALERTVKALEFVQTE 2050
Cdd:NF012221  1685 QKVKDAVAKSEAGVAQGEQNQANaeqdiddAKADAEKRKDDALAKQNEAQQAESDAnAAANDAQSRGEQDASAAENKANQ 1764

                          250
                   ....*....|.
gi 1034632655 2051 SQKDLEITKEN 2061
Cdd:NF012221  1765 AQADAKGAKQD 1775
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 918-1636 5.78e-05

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 49.20  E-value: 5.78e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  918 EEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEMSPAGQISKEELQHEfDLLKKENEQRKRKLQAA 997
Cdd:TIGR00618  187 AKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQK-REAQEEQLKKQQLLKQL 265

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  998 LINRKELLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIYLKQTISEKEVELQHIRK 1077
Cdd:TIGR00618  266 RARIEELRAQEAVLEETQERINRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRR 345

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1078 DLEEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEISENQAIIQKLITSNTDASDGDSVALVKETVVISPPCTGSSEHW 1157
Cdd:TIGR00618  346 LLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQ 425

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1158 KPELEEKILALEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDdynrlQEQFDEQSKENENIGDQLRQLQI 1237
Cdd:TIGR00618  426 LAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQT-----KEQIHLQETRKKAVVLARLLELQ 500

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1238 QVRESIDGKLPSTDQQESCSSTPGLEEPLFKATEQHHTQPVLESNlcpdwpshSEDASALQGGTSVAQIKAQLKEIEAEK 1317
Cdd:TIGR00618  501 EEPCPLCGSCIHPNPARQDIDNPGPLTRRMQRGEQTYAQLETSEE--------DVYHQLTSERKQRASLKEQMQEIQQSF 572

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1318 VELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAE----------SLQQKLESSQLQIAGLEHLR 1387
Cdd:TIGR00618  573 SILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQpeqdlqdvrlHLQQCSQELALKLTALHALQ 652

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1388 ELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDL--IKALHTQLEMQAKEHDERIKQLQVELCEMKQ 1465
Cdd:TIGR00618  653 LTLTQERVREHALSIRVLPKELLASRQLALQKMQSEKEQLTYWKEMLaqCQTLLRELETHIEEYDREFNEIENASSSLGS 732

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1466 kpeEIGEESRAKQQIQRKLQAaliSRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQE 1545
Cdd:TIGR00618  733 ---DLAAREDALNQSLKELMH---QARTVLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEA 806

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1546 ERDklitemdrsllenqslssscESLKLALEGLTEDKEKLVKEIESLKsSKIAESTEWQEKHKELQKEYEILLQSYENVS 1625
Cdd:TIGR00618  807 EIG--------------------QEIPSDEDILNLQCETLVQEEEQFL-SRLEEKSATLGEITHQLLKYEECSKQLAQLT 865

                          730
                   ....*....|.
gi 1034632655 1626 NEAERIQHVVE 1636
Cdd:TIGR00618  866 QEQAKIIQLSD 876
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1383-2025 5.87e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 48.91  E-value: 5.87e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1383 LEHLRELQPKLDELQKLISKKEEdvsyLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDerikqlqvELCE 1462
Cdd:PRK03918   168 GEVIKEIKRRIERLEKFIKRTEN----IEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVK--------ELEE 235

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1463 MKQKPEEIGEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSladvesqvsaqnkekdtvlgrlal 1542
Cdd:PRK03918   236 LKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEK------------------------ 291

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1543 lQEERDKLITEMDRSLLENQSLSSSCESLKLALEGLtedkEKLVKEIESLKSskiaESTEWQEKHKELQKEYEILlqsye 1622
Cdd:PRK03918   292 -AEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGI----EERIKELEEKEE----RLEELKKKLKELEKRLEEL----- 357

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1623 nvsneaeriqhvveavrQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSK-QQKILELEEENDRLRAE 1701
Cdd:PRK03918   358 -----------------EERHELYEEAKAKKEELERLKKRLTGLTPEKLEKELEELEKAKEEiEEEISKITARIGELKKE 420

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1702 VhpagDTAKECMETLLSSNAS--------MKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQANLE 1773
Cdd:PRK03918   421 I----KELKKAIEELKKAKGKcpvcgrelTEEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELI 496

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1774 ATEKHDNQTNVTEEGTQSIPGETEEQDslsmstrptcSESVPSAKSANPAVSKDFSShdeINNYLQQIDQLKERIAGLEE 1853
Cdd:PRK03918   497 KLKELAEQLKELEEKLKKYNLEELEKK----------AEEYEKLKEKLIKLKGEIKS---LKKELEKLEELKKKLAELEK 563

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1854 EKQKNKEFSQTLENEKNTL----LSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAEEEKDDLEErLMNQL 1929
Cdd:PRK03918   564 KLDELEEELAELLKELEELgfesVEELEERLKELEPFYNEYLELKDAEKELEREEKELKKLEEELDKAFEELAE-TEKRL 642

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1930 AELNGSIGNYCQDVTDAQIKNelLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIR--KEYLEKIQGAQKEPGNKSHAK 2007
Cdd:PRK03918   643 EELRKELEELEKKYSEEEYEE--LREEYLELSRELAGLRAELEELEKRREEIKKTLEklKEELEEREKAKKELEKLEKAL 720

                          650
                   ....*....|....*...
gi 1034632655 2008 ELQELLKEKQQEVKQLQK 2025
Cdd:PRK03918   721 ERVEELREKVKKYKALLK 738
PLN02939 PLN02939
transferase, transferring glycosyl groups
 1765-2181 6.38e-05

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 49.13  E-value: 6.38e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1765 NVSKQANLEATEKHDNQTNVTEEGTQSIPGETEEQDSLSMSTRPTC-SESVPSAKSANPAVSKDFSSHDEINNYLQQIDQ 1843
Cdd:PLN02939    41 GFSSQQKKKRGKNIAPKQRSSNSKLQSNTDENGQLENTSLRTVMELpQKSTSSDDDHNRASMQRDEAIAAIDNEQQTNSK 120

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1844 LKERIAGLEEEkqknkEFSQTLEN-EKNTLLsqistkdgelkmlqeevtkMNLLNQQIQEELSRVTKLKETAEEEKDDLE 1922
Cdd:PLN02939   121 DGEQLSDFQLE-----DLVGMIQNaEKNILL-------------------LNQARLQALEDLEKILTEKEALQGKINILE 176

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1923 ERLMNQLAELNGSignycqdvTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEkiqgaqkepgn 2002
Cdd:PLN02939   177 MRLSETDARIKLA--------AQEKIHVEILEEQLEKLRNELLIRGATEGLCVHSLSKELDVLKEENML----------- 237

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2003 kshAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDL----EITKENLAQAVEhrkkaqaelaS 2078
Cdd:PLN02939   238 ---LKDDIQFLKAELIEVAETEERVFKLEKERSLLDASLRELESKFIVAQEDVsklsPLQYDCWWEKVE----------N 304

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2079 FKVLLDDTQSE---AARVLADNLKLKKELQSNKESVKSQMKQKD-----EDLERRLEQAEEKHLKEKKNMQEKLDAlrre 2150
Cdd:PLN02939   305 LQDLLDRATNQvekAALVLDQNQDLRDKVDKLEASLKEANVSKFssykvELLQQKLKLLEERLQASDHEIHSYIQL---- 380

                          410       420       430
                   ....*....|....*....|....*....|...
gi 1034632655 2151 kvhLEETIGEIQVTLNK--KDKEVQQLQENLDS 2181
Cdd:PLN02939   381 ---YQESIKEFQDTLSKlkEESKKRSLEHPADD 410
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2006-2224 6.94e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.22  E-value: 6.94e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2006 AKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDD 2085
Cdd:COG4942     22 AAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEA 101

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2086 TQSEAARVLADNLKLkkelqSNKESVKSQMKQKD-EDLERR---LEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEI 2161
Cdd:COG4942    102 QKEELAELLRALYRL-----GRQPPLALLLSPEDfLDAVRRlqyLKYLAPARREQAEELRADLAELAALRAELEAERAEL 176

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1034632655 2162 QVTLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEE 2224
Cdd:COG4942    177 EALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAA 239
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 826-1068 7.66e-05

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 48.39  E-value: 7.66e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  826 SEQSTLIRSLQSQ--LQNKESEVLEGAERVRHISSKVEELSQALSQ----KELEITKMDQLLLEKKRDVETLQQTIEEKD 899
Cdd:PRK05771    16 SYKDEVLEALHELgvVHIEDLKEELSNERLRKLRSLLTKLSEALDKlrsyLPKLNPLREEKKKVSVKSLEELIKDVEEEL 95

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  900 QQVTEISFSMTEKMVQLNEEKFSL-------------GVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSG-----LKQN 961
Cdd:PRK05771    96 EKIEKEIKELEEEISELENEIKELeqeierlepwgnfDLDLSLLLGFKYVSVFVGTVPEDKLEELKLESDVenveyISTD 175

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  962 YDEMSPAGQISKEELQHEFDLLKKENEQRKRklqaaLINRKELLQRVSRLEEELANLKDeskkeiplsetERGEVEED-- 1039
Cdd:PRK05771   176 KGYVYVVVVVLKELSDEVEEELKKLGFERLE-----LEEEGTPSELIREIKEELEEIEK-----------ERESLLEElk 239

                          250       260       270
                   ....*....|....*....|....*....|....*
gi 1034632655 1040 KENKEYSEKCVTSKC------QEIEIYLKQTISEK 1068
Cdd:PRK05771   240 ELAKKYLEELLALYEyleielERAEALSKFLKTDK 274
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2300-2537 8.54e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.84  E-value: 8.54e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2300 HSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEINMK 2379
Cdd:COG4942     16 AAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAEL 95

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2380 EQKIISLlsgKEEAIQVAIAELRQQHDKEIKELenLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLD 2459
Cdd:COG4942     96 RAELEAQ---KEELAELLRALYRLGRQPPLALL--LSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELE 170

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1034632655 2460 SFVKSMSSLQNDRdrivgdyQQLEERHLSIILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAELIQYRE 2537
Cdd:COG4942    171 AERAELEALLAEL-------EEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAE 241
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2595-3188 9.56e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 48.51  E-value: 9.56e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2595 EKQDLSKEIESLKVSISQLTRQVTALQeegtlglyhAQLKVKEEEVHRLSALFSSSQKRIAELEEELVCVQKEAAKKVGE 2674
Cdd:TIGR02168  233 RLEELREELEELQEELKEAEEELEELT---------AELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQ 303

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2675 IEdKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEELD 2754
Cdd:TIGR02168  304 KQ-ILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLE 382

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2755 ELKRKYdaslkelAQLKEQGLLNRERDALLSETAFSMNSTEENSLSHLEKLNQQLLSKDEQLLHLSSQLEDsynqvqsfs 2834
Cdd:TIGR02168  383 TLRSKV-------AQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELE--------- 446

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2835 KAMASLQNERDHLWNELEKFRKSEEGKQRSAAQPSTSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELH 2914
Cdd:TIGR02168  447 EELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLS 526

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2915 PLKAQLQEYQ-----------------DKTKAFQImQEELRQENLSWQH--ELHQLRMEKSSWEIHERRMK-EQYLMAIS 2974
Cdd:TIGR02168  527 ELISVDEGYEaaieaalggrlqavvveNLNAAKKA-IAFLKQNELGRVTflPLDSIKGTEIQGNDREILKNiEGFLGVAK 605

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2975 DKDQQLSHLQNLIRELRSSSS------QTQPLKVQYQRQASPET----SASPDGSQN----------LVYETEL--LRTQ 3032
Cdd:TIGR02168  606 DLVKFDPKLRKALSYLLGGVLvvddldNALELAKKLRPGYRIVTldgdLVRPGGVITggsaktnssiLERRREIeeLEEK 685

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 3033 LNDSLKEIHQKELRIQQLNSNFSQLLEEKNTLSIQLCDTSQSLRENQQHYGDLLNHCAVLEKQVQELQAVSKEKgpLNID 3112
Cdd:TIGR02168  686 IEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTEL--EAEI 763

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 3113 VAPGAPQEKNGVHRKSDPEELREPQQSFSEAQQQLCNTRQEVNELRKLLEEERD---------------------QRVAA 3171
Cdd:TIGR02168  764 EELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEeaanlrerleslerriaaterRLEDL 843

                          650
                   ....*....|....*..
gi 1034632655 3172 ENALSVAEEQIRRLEHS 3188
Cdd:TIGR02168  844 EEQIEELSEDIESLAAE 860
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 35-615 9.87e-05

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 48.19  E-value: 9.87e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655   35 HQESDMEFNNTTQEDVQERLAYAEQLVVELKDIIRQKDVQLQQKDEALQEERKAADNKIKKLKLHAKAKLTSLNKYIEEM 114
Cdd:pfam15921   75 HIERVLEEYSHQVKDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTVHEL 154

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  115 KAQG--------------------------------GTVLPTEPQSEEQLSKHDKSSTEEEMEIEKIKHK-LQEKEELIS 161
Cdd:pfam15921  155 EAAKclkedmledsntqieqlrkmmlshegvlqeirSILVDFEEASGKKIYEHDSMSTMHFRSLGSAISKiLRELDTEIS 234

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  162 TLQAQLTQAQAEQPAQSSTEMEEFVMMKQQLQEK-EEFISTLQAQL-----------SQTQAEQAAQVVREKDARFETQV 229
Cdd:pfam15921  235 YLKGRIFPVEDQLEALKSESQNKIELLLQQHQDRiEQLISEHEVEItgltekassarSQANSIQSQLEIIQEQARNQNSM 314

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  230 RL-HEDELLQLVTQadVETEMQQKLRVLQRKLEEHEESLVGRAQVVDLLQQELTAAEQRNQILSQQLQQMEAEHNTLRNT 308
Cdd:pfam15921  315 YMrQLSDLESTVSQ--LRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKE 392

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  309 VETEREESKILLEK-----MELEVAERKLSFHNLQ-EEMHHLLEQFEQagQAQAELESRYSALEQKHKAeMEEKTSHILS 382
Cdd:pfam15921  393 LSLEKEQNKRLWDRdtgnsITIDHLRRELDDRNMEvQRLEALLKAMKS--ECQGQMERQMAAIQGKNES-LEKVSSLTAQ 469

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  383 LQKTGQELQSACDALKDQnsKLLQDKNEQAVQS-AQTIQQLEDQLQQKSKEISQFLNRLPLQ----QHETASQTSFPDVY 457
Cdd:pfam15921  470 LESTKEMLRKVVEELTAK--KMTLESSERTVSDlTASLQEKERAIEATNAEITKLRSRVDLKlqelQHLKNEGDHLRNVQ 547

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  458 NE---------GTQAVTE---ENIASLQKRVVELENEKGALLLSS-----------IELEELKAENEKLSSQITLLEAQn 514
Cdd:pfam15921  548 TEcealklqmaEKDKVIEilrQQIENMTQLVGQHGRTAGAMQVEKaqlekeindrrLELQEFKILKDKKDAKIRELEAR- 626

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  515 rtgEADREVSEISIVDIANKRSSSAEESGQ--DVLENTFSQKHKELSVLLLEM---------KEAQEEIAFLKLQLQGKR 583
Cdd:pfam15921  627 ---VSDLELEKVKLVNAGSERLRAVKDIKQerDQLLNEVKTSRNELNSLSEDYevlkrnfrnKSEEMETTTNKLKMQLKS 703

                          650       660       670
                   ....*....|....*....|....*....|..
gi 1034632655  584 AEEADHEVldQKEMKQMEGEGIAPIKMKVFLE 615
Cdd:pfam15921  704 AQSELEQT--RNTLKSMEGSDGHAMKVAMGMQ 733
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 710-904 1.24e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.45  E-value: 1.24e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  710 LDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLSQVKELS-MVTELRAQVKQLEMNLAEAERQRRLDYESQTA 788
Cdd:COG4942     22 AAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALArRIRALEQELAALEAELAELEKEIAELRAELEA 101

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  789 HDNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALS 868
Cdd:COG4942    102 QKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLA 181

                          170       180       190
                   ....*....|....*....|....*....|....*.
gi 1034632655  869 QKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTE 904
Cdd:COG4942    182 ELEEERAALEALKAERQKLLARLEKELAELAAELAE 217
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2284-2504 1.25e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.45  E-value: 1.25e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2284 ENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQ 2363
Cdd:COG4942     21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELE 100

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2364 ASRE-LTSRLHEEINMKEQKIISLLSGKEEAIQVA-----IAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKT 2437
Cdd:COG4942    101 AQKEeLAELLRALYRLGRQPPLALLLSPEDFLDAVrrlqyLKYLAPARREQAEELRADLAELAALRAELEAERAELEALL 180

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1034632655 2438 NQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSIILEKDQLIQEAAAEN 2504
Cdd:COG4942    181 AELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAG 247
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1939-2676 1.26e-04

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 48.19  E-value: 1.26e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1939 YCQDVTDAQIK----NELLESEMKNLKKCVSELEEEKQQLVKEKTKVeSEIRKEYLEKIQGAQKEPGNKSH----AKELQ 2010
Cdd:pfam15921   83 YSHQVKDLQRRlnesNELHEKQKFYLRQSVIDLQTKLQEMQMERDAM-ADIRRRESQSQEDLRNQLQNTVHeleaAKCLK 161

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2011 E-LLKEKQQEVKQLQKDCIRYQEKISALERTVkaLEFVQTESQKdleITKENLAQAVEHRKKAQAelasFKVLLDDTQSE 2089
Cdd:pfam15921  162 EdMLEDSNTQIEQLRKMMLSHEGVLQEIRSIL--VDFEEASGKK---IYEHDSMSTMHFRSLGSA----ISKILRELDTE 232

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2090 AARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKD 2169
Cdd:pfam15921  233 ISYLKGRIFPVEDQLEALKSESQNKIELLLQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQARNQN 312

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2170 KEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVIDeaKKWERKFSDAIQSKEEEIRLKEDNCSvLKDQLRQM--SIHME 2247
Cdd:pfam15921  313 SMYMRQLSDLESTVSQLRSELREAKRMYEDKIEELE--KQLVLANSELTEARTERDQFSQESGN-LDDQLQKLlaDLHKR 389

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2248 ELKINISRlEHDKQIWESKAQTEVQLQ-------------QKVCDTLQGENKELLSQLEETRHLYHSSQNELAKLESELK 2314
Cdd:pfam15921  390 EKELSLEK-EQNKRLWDRDTGNSITIDhlrrelddrnmevQRLEALLKAMKSECQGQMERQMAAIQGKNESLEKVSSLTA 468

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2315 SLKDQLTDLSNSLEKCKEQKGNLEgiirQQEADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKIISLLSGKE--- 2391
Cdd:pfam15921  469 QLESTKEMLRKVVEELTAKKMTLE----SSERTVSDLTASLQEKERAIEATNAEITKLRSRVDLKLQELQHLKNEGDhlr 544

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2392 ------EAIQVAIAE-------LRQQhdkeIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQL 2458
Cdd:pfam15921  545 nvqtecEALKLQMAEkdkvieiLRQQ----IENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEFKILKDKKDAKI 620

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2459 DSFVKSMSSLQNDRDRIVGDYQQLEERHLSIILEKDQLIQE---AAAENNKLKEEI----RGLRSHMDDLNSENAKLDAE 2531
Cdd:pfam15921  621 RELEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQLLNEvktSRNELNSLSEDYevlkRNFRNKSEEMETTTNKLKMQ 700

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2532 LIQYREDLNQVITIKDSQQK---QLLEVQLQQNKELENKYAKLEEKLKESEEANEDL---RRSFNALQEEKQDLSKEIES 2605
Cdd:pfam15921  701 LKSAQSELEQTRNTLKSMEGsdgHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAMtnaNKEKHFLKEEKNKLSQELST 780

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1034632655 2606 LKVSISQLTRQVTALQEEgtlglyHAQLKVK----EEEVHRLSALFSSSQKRIAELEEELVCVQKEAAKKVGEIE 2676
Cdd:pfam15921  781 VATEKNKMAGELEVLRSQ------ERRLKEKvanmEVALDKASLQFAECQDIIQRQEQESVRLKLQHTLDVKELQ 849
COG5022 COG5022
Myosin heavy chain [General function prediction only];
1847-2383 1.29e-04

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 48.15  E-value: 1.29e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1847 RIAGLEEEKQKNKEFSQT-LENEKNTLLSQIS-TKDGELKMLQEEVTKMNLLNQQIQ-EELSRVTKLKETAE----EEKD 1919
Cdd:COG5022    870 YLQSAQRVELAERQLQELkIDVKSISSLKLVNlELESEIIELKKSLSSDLIENLEFKtELIARLKKLLNNIDleegPSIE 949

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1920 DLEERLMNQLAELNGSIGNYCQDVTDAQIKNELLE-------SEMKNLKKCVSELEEEKQQLVKEKTKVESEIRK--EYL 1990
Cdd:COG5022    950 YVKLPELNKLHEVESKLKETSEEYEDLLKKSTILVregnkanSELKNFKKELAELSKQYGALQESTKQLKELPVEvaELQ 1029

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1991 EKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEIT-KENLAQAVEHR 2069
Cdd:COG5022   1030 SASKIISSESTELSILKPLQKLKGLLLLENNQLQARYKALKLRRENSLLDDKQLYQLESTENLLKTINvKDLEVTNRNLV 1109

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2070 KKAQAE----LASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQKDeDLERRLEQAEEKHLKEKKNMQEK-L 2144
Cdd:COG5022   1110 KPANVLqfivAQMIKLNLLQEISKFLSQLVNTLEPVFQKLSVLQLELDGLFWEA-NLEALPSPPPFAALSEKRLYQSAlY 1188

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2145 DALRREKVHLEETIGEIQVTLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQ---SK 2221
Cdd:COG5022   1189 DEKSKLSSSEVNDLKNELIALFSKIFSGWPRGDKLKKLISEGWVPTEYSTSLKGFNNLNKKFDTPASMSNEKLLSllnSI 1268

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2222 EEEIRLKEDNCSVLKDQLRQMSIHMEELKINisRLEHDKQIWESKAQTEVQLQQKVCDT--LQGENKEL---LSQLEETR 2296
Cdd:COG5022   1269 DNLLSSYKLEEEVLPATINSLLQYINVGLFN--ALRTKASSLRWKSATEVNYNSEELDDwcREFEISDVdeeLEELIQAV 1346

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2297 HLYHSSQNELAKLESELKSLKDQLTDLSNSLeKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEI 2376
Cdd:COG5022   1347 KVLQLLKDDLNKLDELLDACYSLNPAEIQNL-KSRYDPADKENNLPKEILKKIEALLIKQELQLSLEGKDETEVHLSEIF 1425


                   ....*..
gi 1034632655 2377 NMKEQKI 2383
Cdd:COG5022   1426 SEEKSLI 1432
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
673-1124 1.32e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 47.73  E-value: 1.32e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  673 AVPDIGQCHQDELERLKSQILELE-LNFHKAQEIYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLlsq 751
Cdd:PRK02224   177 GVERVLSDQRGSLDQLKAQIEEKEeKDLHERLNGLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERREEL--- 253

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  752 vkelsmvTELRAQVKQLEMNLAEAERQRR-LDYESQTAHDNLLT--EQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQ 828
Cdd:PRK02224   254 -------ETLEAEIEDLRETIAETEREREeLAEEVRDLRERLEEleEERDDLLAEAGLDDADAEAVEARREELEDRDEEL 326

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  829 STLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQV------ 902
Cdd:PRK02224   327 RDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFgdapvd 406

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  903 ----TEISFSMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKK----EQVEEDNEVSSGLKQNYDEmspagqisKE 974
Cdd:PRK02224   407 lgnaEDFLEELREERDELREREAELEATLRTARERVEEAEALLEAGKcpecGQPVEGSPHVETIEEDRER--------VE 478

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  975 ELQHEFDLLKKENEQRKRKLQAAlINRKELLQRVSRLEEELANLKDeskkeipLSETERGEVEEDKEnkeysekcvtsKC 1054
Cdd:PRK02224   479 ELEAELEDLEEEVEEVEERLERA-EDLVEAEDRIERLEERREDLEE-------LIAERRETIEEKRE-----------RA 539

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1034632655 1055 QEieiyLKQTISEKEVELQHIRKDLEEKLAAEEQFQALVKQMNQTLQDKTNQIDLL------QAEISENQAIIQKL 1124
Cdd:PRK02224   540 EE----LRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLerirtlLAAIADAEDEIERL 611
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
699-951 1.65e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 47.60  E-value: 1.65e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  699 FHKAQeiyeknldeKAKEISNLNQLIEEF-------KKNADNNSSAFTALSEERDQLLSQVKELSMVTELRAQVKQLEMN 771
Cdd:COG4913    197 LHKTQ---------SFKPIGDLDDFVREYmleepdtFEAADALVEHFDDLERAHEALEDAREQIELLEPIRELAERYAAA 267

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  772 LAEAERQRRLD-----YESQTAHDnLLTEQIHSLSIEakskdvkIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEV 846
Cdd:COG4913    268 RERLAELEYLRaalrlWFAQRRLE-LLEAELEELRAE-------LARLEAELERLEARLDALREELDELEAQIRGNGGDR 339

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  847 LEGAER--------VRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNE 918
Cdd:COG4913    340 LEQLEReierlereLEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRR 419

                          250       260       270
                   ....*....|....*....|....*....|...
gi 1034632655  919 EKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEED 951
Cdd:COG4913    420 ELRELEAEIASLERRKSNIPARLLALRDALAEA 452
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 153-1047 1.69e-04

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 47.66  E-value: 1.69e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  153 LQEKEELISTLQAQLTQAQAEQPAQSSTEMEEFVMMKQQLQEKEEFISTLQAQLSQTQAEQAAQVVREKDARFETQVRLH 232
Cdd:pfam02463  176 KKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIES 255

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  233 EDELLQLVTQADVETEMQQKLRVLQRKLEEHEESLVGRAQvvDLLQQELTAAEQRNQILSQQLQQMEAEhNTLRNTVETE 312
Cdd:pfam02463  256 SKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEE--EELKSELLKLERRKVDDEEKLKESEKE-KKKAEKELKK 332

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  313 REESKILLEKMELEVAERKLSFHNLQEEMHHLLEQFEQAGQAQAELESRYSALEQKHKAEMEEKTSHILSLQKTGQELQS 392
Cdd:pfam02463  333 EKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLE 412

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  393 ACDALKDQNSKLLQDKNEQAVQSAQTIQQLEDQLQQKSKEISQFLNRLPLQQHETASQTSFPDVYNEGTQAVTEENIASL 472
Cdd:pfam02463  413 LARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSR 492

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  473 QKRVVELENEKGALLLSSIELEELKAENEKLSSQITLLEAQNRTGEADREVSEISIVDIANKRSSSAEESGQDVLENTFS 552
Cdd:pfam02463  493 QKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTE 572

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  553 QKHKELSVLLLEMKEAQEEIAFLKLQLQGKRAEEADHEVLDQKEMKQMEGEGIAPIKMKVFLEDTGQDFPLMPNEESSLP 632
Cdd:pfam02463  573 LPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGV 652

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  633 AVEKEQASTEHQSRTSEEISLNDAGVELKSTKQdgdKSLSAVPDIGQCHQDELERLKSQILELELNFHKAQEIYEKNLDE 712
Cdd:pfam02463  653 SLEEGLAEKSEVKASLSELTKELLEIQELQEKA---ESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQE 729

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  713 KAKEISNLNQLIEEFKKN--ADNNSSAFTALSEERDQLLSQVKELSMVTELRAQVKQLEMNLAEAERQRRLDYESQTAHD 790
Cdd:pfam02463  730 AQDKINEELKLLKQKIDEeeEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEE 809

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  791 NLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEgaervrhisSKVEELSQALSQK 870
Cdd:pfam02463  810 LKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEE---------LLQELLLKEEELE 880

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  871 ELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEE 950
Cdd:pfam02463  881 EQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEE 960

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  951 DNEVSSGLKQN--YDEMSPAGQISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELANLKDESKKEIPL 1028
Cdd:pfam02463  961 RNKRLLLAKEElgKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQRLKEFLELFVSINKGWNKVFFYL 1040

                          890
                   ....*....|....*....
gi 1034632655 1029 SETERGEVEEDKENKEYSE 1047
Cdd:pfam02463 1041 ELGGSAELRLEDPDDPFSG 1059
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 128-920 1.82e-04

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 47.73  E-value: 1.82e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  128 SEEQLSKHDKSSTEEEMEIEKIKHKLQEKEELISTLQAQLTQAQAEQPAQSSTEMEEFVMMKQQLQEKEEFISTLQAQLS 207
Cdd:TIGR00606  299 TDEQLNDLYHNHQRTVREKERELVDCQRELEKLNKERRLLNQEKTELLVEQGRLQLQADRHQEHIRARDSLIQSLATRLE 378

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  208 QTQAEQAAQVVREKDARFETQVRLHEDELLqlvTQADVETEMQQKLRVLQRKLEEHEESLVGRAQVVDLLQQELTAAEQR 287
Cdd:TIGR00606  379 LDGFERGPFSERQIKNFHTLVIERQEDEAK---TAAQLCADLQSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEE 455

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  288 NQILSQQLQQMEAEHNtlrntvetereesKILLEKMELEVAERKLSFHNLQEEMHHLLEQFEQAGQAQAELESRYSALEQ 367
Cdd:TIGR00606  456 LKFVIKELQQLEGSSD-------------RILELDQELRKAERELSKAEKNSLTETLKKEVKSLQNEKADLDRKLRKLDQ 522

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  368 khkaEMEEKTSHILSLQKTGQELQSACDA---LKDQNSKLLQDKNEQAVQSAQTiQQLEDQLQQKSKEISQFLNRLPLQQ 444
Cdd:TIGR00606  523 ----EMEQLNHHTTTRTQMEMLTKDKMDKdeqIRKIKSRHSDELTSLLGYFPNK-KQLEDWLHSKSKEINQTRDRLAKLN 597

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  445 HETASQTSFPDVYNEGTQAVTEE---------NIASLQKRVVELENEKGALLLSSIELEELKAENEKLSSQITLLEAQN- 514
Cdd:TIGR00606  598 KELASLEQNKNHINNELESKEEQlssyedklfDVCGSQDEESDLERLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENq 677

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  515 -------RTGEADREVSEIsIVDIANKRSSSAEEsgQDVLENTFSQKHKELSVLLL-------EMKEAQEEIAFLKLQLQ 580
Cdd:TIGR00606  678 sccpvcqRVFQTEAELQEF-ISDLQSKLRLAPDK--LKSTESELKKKEKRRDEMLGlapgrqsIIDLKEKEIPELRNKLQ 754

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  581 GKRAEEADHEVLDQKEMKQMEGEGIAPIKMKVFLEDTGqdfpLMPNEESSLPAVEKEqasTEHQSRTSEEISLNDAGVEL 660
Cdd:TIGR00606  755 KVNRDIQRLKNDIEEQETLLGTIMPEEESAKVCLTDVT----IMERFQMELKDVERK---IAQQAAKLQGSDLDRTVQQV 827

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  661 KSTKQDGDKSLSAVPDIG--------------QCHQDELERLKSQILELELNFHKAQEiYEKNLDEKAKEISNLNQLIEE 726
Cdd:TIGR00606  828 NQEKQEKQHELDTVVSKIelnrkliqdqqeqiQHLKSKTNELKSEKLQIGTNLQRRQQ-FEEQLVELSTEVQSLIREIKD 906

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  727 FKKNADNNSSAFTALSEERDQLLSQVKELSMVTELRAQ---------------------------VKQLEMNLA------ 773
Cdd:TIGR00606  907 AKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVNdikekvknihgymkdienkiqdgkddyLKQKETELNtvnaql 986

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  774 -----------EAERQRRLDYESQTAHDNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNK 842
Cdd:TIGR00606  987 eecekhqekinEDMRLMRQDIDTQKIQERWLQDNLTLRKRENELKEVEEELKQHLKEMGQMQVLQMKQEHQKLEENIDLI 1066

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1034632655  843 ESEVLEGAERVRHISSKVEELSQALSQKELEITKmdqlllEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNEEK 920
Cdd:TIGR00606 1067 KRNHVLALGRQKGYEKEIKHFKKELREPQFRDAE------EKYREMMIVMRTTELVNKDLDIYYKTLDQAIMKFHSMK 1138
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1986-2179 1.99e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 47.07  E-value: 1.99e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1986 RKEYLEKIQGaQKEPGNKSHAKELQELLKEKQQEVKQLQKDciryQEKISALERTVKALEFVQTESQKDLEITK--ENLA 2063
Cdd:COG4717     54 EADELFKPQG-RKPELNLKELKELEEELKEAEEKEEEYAEL----QEELEELEEELEELEAELEELREELEKLEklLQLL 128

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2064 QAVEHRKKAQAELASFKVLLDDTQSEAARVladnlklkKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEK 2143
Cdd:COG4717    129 PLYQELEALEAELAELPERLEELEERLEEL--------RELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEE 200

                          170       180       190
                   ....*....|....*....|....*....|....*.
gi 1034632655 2144 LDALRREKVHLEETIGEIQVTLNKKDKEVQQLQENL 2179
Cdd:COG4717    201 LEELQQRLAELEEELEEAQEELEELEEELEQLENEL 236
PTZ00121 PTZ00121
MAEBL; Provisional
 698-1242 2.10e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 47.44  E-value: 2.10e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  698 NFHKAQEIYEKNLDEKAKEISNlnqlIEEFKKNADNNSSAFTALSEERDQLLSQVKELSMV---TELRAQVKQLEMNLAE 774
Cdd:PTZ00121  1210 EERKAEEARKAEDAKKAEAVKK----AEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFArrqAAIKAEEARKADELKK 1285

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  775 AERQRRLDyESQTAHDNLLTEQIHSLSIEAKSKD---VKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAE 851
Cdd:PTZ00121  1286 AEEKKKAD-EAKKAEEKKKADEAKKKAEEAKKADeakKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEE 1364

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  852 RvrhisSKVEELSQALSQKELEITKMDQlllEKKRDVETLQQTIEEKDQQVTEISFSMTEKMvqlneekfslgvEIKTLK 931
Cdd:PTZ00121  1365 K-----AEAAEKKKEEAKKKADAAKKKA---EEKKKADEAKKKAEEDKKKADELKKAAAAKK------------KADEAK 1424

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  932 EQLNLLSRAEEAKKEQveEDNEVSSGLKQNYDEMSPAGQISKE-ELQHEFDLLKKENEQRKRKLQAalinrKELLQRVSR 1010
Cdd:PTZ00121  1425 KKAEEKKKADEAKKKA--EEAKKADEAKKKAEEAKKAEEAKKKaEEAKKADEAKKKAEEAKKADEA-----KKKAEEAKK 1497

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1011 LEEELANLKDESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIYLKQTISEKEVELQHIRKDLEEKLAAEEQfq 1090
Cdd:PTZ00121  1498 KADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEED-- 1575

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1091 alvKQMNQTLQDKTNQIDllQAEISENQAIIQKLITSNTDASDGDSVALVKETVVISppctGSSEHWKPELEEKILALEK 1170
Cdd:PTZ00121  1576 ---KNMALRKAEEAKKAE--EARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKK----AEEEKKKVEQLKKKEAEEK 1646

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1034632655 1171 EKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVRES 1242
Cdd:PTZ00121  1647 KKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKA 1718
mukB PRK04863
chromosome partition protein MukB;
154-435 2.35e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 47.26  E-value: 2.35e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  154 QEKEELISTLQAQLTQAQAEQPAQSSTEMEEFVMMKQQLQEKEEFISTLQAQLS---------QTQAEQAAQVVREKDaR 224
Cdd:PRK04863   347 QEKIERYQADLEELEERLEEQNEVVEEADEQQEENEARAEAAEEEVDELKSQLAdyqqaldvqQTRAIQYQQAVQALE-R 425

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  225 FETQVRLH-------EDELLQLVTQADVETE----MQQKLRVLQRKLEEHEESL---------VGRAQVVDLLQQELTAA 284
Cdd:PRK04863   426 AKQLCGLPdltadnaEDWLEEFQAKEQEATEellsLEQKLSVAQAAHSQFEQAYqlvrkiageVSRSEAWDVARELLRRL 505

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  285 EQRnQILSQQLQQMEAEHNTLRNTVETEREESKILLE-KMELEVAErkLSFHNLQEEMHHLLEQFEQAGQAQAELESRYS 363
Cdd:PRK04863   506 REQ-RHLAEQLQQLRMRLSELEQRLRQQQRAERLLAEfCKRLGKNL--DDEDELEQLQEELEARLESLSESVSEARERRM 582

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1034632655  364 ALEQkhkaEMEEKTSHILSLQKTGQELQSACDALKDqnsklLQDKNEQAVQSAQTIQQLEDQLQQKSKEISQ 435
Cdd:PRK04863   583 ALRQ----QLEQLQARIQRLAARAPAWLAAQDALAR-----LREQSGEEFEDSQDVTEYMQQLLERERELTV 645
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1467-1706 2.38e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 46.30  E-value: 2.38e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1467 PEEIGEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEE 1546
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1547 RDKLITEMDRSLLENQSLSSScESLKLALEGltEDKEKLVKEIESLKSSkiaestewQEKHKELQKEYEILLQSYENVSN 1626
Cdd:COG4942     99 LEAQKEELAELLRALYRLGRQ-PPLALLLSP--EDFLDAVRRLQYLKYL--------APARREQAEELRADLAELAALRA 167

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1627 EAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHPAG 1706
Cdd:COG4942    168 ELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAG 247
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
681-1044 2.40e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 46.96  E-value: 2.40e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  681 HQDELERLKSQILELELNFHKAQEiyekNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLSQVKEL-SMVT 759
Cdd:PRK02224   354 LEERAEELREEAAELESELEEARE----AVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELrEREA 429

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  760 ELRAQVKQLEMNLAEAERQRRLDYESQTAHDnlLTEQIHSLSIEakSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSqL 839
Cdd:PRK02224   430 ELEATLRTARERVEEAEALLEAGKCPECGQP--VEGSPHVETIE--EDRERVEELEAELEDLEEEVEEVEERLERAED-L 504

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  840 QNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDqlllEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNEE 919
Cdd:PRK02224   505 VEAEDRIERLEERREDLEELIAERRETIEEKRERAEELR----ERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSK 580

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  920 KFSLGVEIKTLKEQLNLLSRAEEAKkEQVEEDNEVSSGLKQNYDEmspagqiSKEELQHEFD----LLKKENEQRKRKLQ 995
Cdd:PRK02224   581 LAELKERIESLERIRTLLAAIADAE-DEIERLREKREALAELNDE-------RRERLAEKRErkreLEAEFDEARIEEAR 652

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*....
gi 1034632655  996 AALINRKELLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKENKE 1044
Cdd:PRK02224   653 EDKERAEEYLEQVEEKLDELREERDDLQAEIGAVENELEELEELRERRE 701
PLN02939 PLN02939
transferase, transferring glycosyl groups
 625-992 3.07e-04

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 46.82  E-value: 3.07e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  625 PNEESSLPAVEKEQASTEHQSRTSEEISLNDAGVELKSTKQDGDKSLSAVPDIGQCHQDeleRLKSQILELelNFHKAQE 704
Cdd:PLN02939    40 RGFSSQQKKKRGKNIAPKQRSSNSKLQSNTDENGQLENTSLRTVMELPQKSTSSDDDHN---RASMQRDEA--IAAIDNE 114

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  705 IYEKNLDEKakEISNLNqlIEEFKKNADNNSSAFTALSEERDQLLSQV-KELSMVTELRAQVKQLEMNLAEAERQRRLDY 783
Cdd:PLN02939   115 QQTNSKDGE--QLSDFQ--LEDLVGMIQNAEKNILLLNQARLQALEDLeKILTEKEALQGKINILEMRLSETDARIKLAA 190

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  784 ESQtAHDNLLTEQI----HSLSIEAKSKDVKIEVLQNELDDVQlqfsEQSTLIRSLQSQLQNKESEVLEGAERV------ 853
Cdd:PLN02939   191 QEK-IHVEILEEQLeklrNELLIRGATEGLCVHSLSKELDVLK----EENMLLKDDIQFLKAELIEVAETEERVfkleke 265

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  854 -RHISSKVEELSQALSQKELEITKMDQLLLEKKRD-VETLQQTIEEKDQQVTEISFSMT-----EKMVQLNEEKFSLGVE 926
Cdd:PLN02939   266 rSLLDASLRELESKFIVAQEDVSKLSPLQYDCWWEkVENLQDLLDRATNQVEKAALVLDqnqdlRDKVDKLEASLKEANV 345

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1034632655  927 IKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEmspagqiSKEELQHEFDLLKKENEQRKR 992
Cdd:PLN02939   346 SKFSSYKVELLQQKLKLLEERLQASDHEIHSYIQLYQE-------SIKEFQDTLSKLKEESKKRSL 404
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 1843-2174 3.14e-04

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 46.66  E-value: 3.14e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1843 QLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQIST-KDGELKMLQEEVTKMNLLNQQIQEELSRVTKlketaEEEKDDL 1921
Cdd:pfam17380  288 QQQEKFEKMEQERLRQEKEEKAREVERRRKLEEAEKaRQAEMDRQAAIYAEQERMAMERERELERIRQ-----EERKREL 362

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1922 EERLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKcVSELEEEKQQLVKEKTKVESEIRKEYLEKIQgaqkepg 2001
Cdd:pfam17380  363 ERIRQEEIAMEISRMRELERLQMERQQKNERVRQELEAARK-VKILEEERQRKIQQQKVEMEQIRAEQEEARQ------- 434

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2002 nkshaKELQELLKEKQQEVKQLQKDCIRYQEKISALErtvkalefvqtesQKDLEITKENLAQAVEHRKKAQAELASFKV 2081
Cdd:pfam17380  435 -----REVRRLEEERAREMERVRLEEQERQQQVERLR-------------QQEEERKRKKLELEKEKRDRKRAEEQRRKI 496

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2082 LLDDTQSEAARVLADNLK---LKKELQSNKESVKSQMKQKDEDLERRleqaEEKHLKEKKNMQEKLDALRREKVHLEETI 2158
Cdd:pfam17380  497 LEKELEERKQAMIEEERKrklLEKEMEERQKAIYEEERRREAEEERR----KQQEMEERRRIQEQMRKATEERSRLEAME 572

                          330
                   ....*....|....*.
gi 1034632655 2159 GEIQVTLNKKDKEVQQ 2174
Cdd:pfam17380  573 REREMMRQIVESEKAR 588
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 276-513 3.86e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.91  E-value: 3.86e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  276 LLQQELTAAEQRNQILSQQLQQMEAEHNTLRNTVETEREESKILLEkmELEVAERKLSfhNLQEEMHHLLEQFEQAGQAQ 355
Cdd:COG4942     10 LLALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLK--QLAALERRIA--ALARRIRALEQELAALEAEL 85

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  356 AELESRYSALEQKHKAEMEEKTSHILSLQKTGQelQSACDALkdqnskLLQDKNEQAVQSAQTIQQLEDQLQQKSKEISQ 435
Cdd:COG4942     86 AELEKEIAELRAELEAQKEELAELLRALYRLGR--QPPLALL------LSPEDFLDAVRRLQYLKYLAPARREQAEELRA 157

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1034632655  436 FLNRLPLQQHETASQTSFPDVYNEGTQAVTEENIASLQKRVVELENEKGALLLSSIELEELKAENEKLSSQITLLEAQ 513
Cdd:COG4942    158 DLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAE 235
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
972-1602 5.02e-04

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 45.83  E-value: 5.02e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  972 SKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELANLkDESKKEIPLSETERGEVEEDKENKEysekcvt 1051
Cdd:PRK03918   187 RTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKEL-EELKEEIEELEKELESLEGSKRKLE------- 258

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1052 SKCQEIEIYLKQTISEKEvELQHIRKDLEEKLAAEEQFQALVKQMNQTLqDKTNQIDLLQAEISENQAIIQKLITSNTda 1131
Cdd:PRK03918   259 EKIRELEERIEELKKEIE-ELEEKVKELKELKEKAEEYIKLSEFYEEYL-DELREIEKRLSRLEEEINGIEERIKELE-- 334

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1132 sdgdsvalvketvvisppctgSSEHWKPELEEKILALEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDY 1211
Cdd:PRK03918   335 ---------------------EKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTPEKLEKEL 393

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1212 NRLQEQFDEQSKENENIGDQLRQLQIQVRESIDGKLPSTDQQESCsstPGLEEPLfkaTEQHhtqpvlESNLCPDWPSHS 1291
Cdd:PRK03918   394 EELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKC---PVCGREL---TEEH------RKELLEEYTAEL 461

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1292 EDASAlqggtSVAQIKAQLKEIEAEKVELElKVSSTTSELTKKSEEVFQLQEQINK-QGLEIESLKTVSHEAEVHAESLQ 1370
Cdd:PRK03918   462 KRIEK-----ELKEIEEKERKLRKELRELE-KVLKKESELIKLKELAEQLKELEEKlKKYNLEELEKKAEEYEKLKEKLI 535

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1371 qKLESSQLQIAG-LEHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEH 1449
Cdd:PRK03918   536 -KLKGEIKSLKKeLEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKELEPFYNEYLELKDAEKEL 614

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1450 DERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLqaalisrkEALKENKSlQEELSLARGTIERLTKSLADVESQVSAQ 1529
Cdd:PRK03918   615 EREEKELKKLEEELDKAFEELAETEKRLEELRKEL--------EELEKKYS-EEEYEELREEYLELSRELAGLRAELEEL 685

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1034632655 1530 NKEKDTVLGRLALLQEERDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESTE 1602
Cdd:PRK03918   686 EKRREEIKKTLEKLKEELEEREKAKKELEKLEKALERVEELREKVKKYKALLKERALSKVGEIASEIFEELTE 758
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
48-526 5.74e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 45.68  E-value: 5.74e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655   48 EDVQERLAYAEQLVVELKDIIRQKDVQLQQKD-EALQEERKAADNKIKKLKLHAKAKLTSLNKYIEEMKAQGGtvlptep 126
Cdd:COG4913    265 AAARERLAELEYLRAALRLWFAQRRLELLEAElEELRAELARLEAELERLEARLDALREELDELEAQIRGNGG------- 337

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  127 QSEEQLSKhdkssteeemEIEKIKHKLQEKEELISTLQAQLTQAQAEQPAqsstEMEEFVMMKQQLQEKEEFISTLQAQL 206
Cdd:COG4913    338 DRLEQLER----------EIERLERELEERERRRARLEALLAALGLPLPA----SAEEFAALRAEAAALLEALEEELEAL 403

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  207 SQTQAEQAAQVVREKDARFETqvrlhEDELLQLVTQAD-VETEMQQKLRVLQRKLEEHEESLVGRAQVVDLLQQEL---T 282
Cdd:COG4913    404 EEALAEAEAALRDLRRELREL-----EAEIASLERRKSnIPARLLALRDALAEALGLDEAELPFVGELIEVRPEEErwrG 478

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  283 AAE-----QRNQIL--SQQLQQMEA--EHNTLRNTVETEREESKILLEKMELEVAE---RKLSF--HNLQEEMHHLL--- 345
Cdd:COG4913    479 AIErvlggFALTLLvpPEHYAAALRwvNRLHLRGRLVYERVRTGLPDPERPRLDPDslaGKLDFkpHPFRAWLEAELgrr 558

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  346 ---------EQFEQAGQA-----QAelesrysaleqKHKAEMEEK--TSHILSLQKTGQelqsacdalkdQNSKLLQDKN 409
Cdd:COG4913    559 fdyvcvdspEELRRHPRAitragQV-----------KGNGTRHEKddRRRIRSRYVLGF-----------DNRAKLAALE 616

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  410 EQAVQSAQTIQQLEDQLQQKSKEISQFLNRlpLQQHETASQTSFPDVynegtqavteeNIASLQKRVVELENEKGALLLS 489
Cdd:COG4913    617 AELAELEEELAEAEERLEALEAELDALQER--REALQRLAEYSWDEI-----------DVASAEREIAELEAELERLDAS 683

                          490       500       510
                   ....*....|....*....|....*....|....*..
gi 1034632655  490 SIELEELKAENEKLSSQITllEAQNRTGEADREVSEI 526
Cdd:COG4913    684 SDDLAALEEQLEELEAELE--ELEEELDELKGEIGRL 718
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1160-1645 5.99e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 45.78  E-value: 5.99e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1160 ELEEKILALEKEKEQLQK---KLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQ 1236
Cdd:TIGR04523  215 SLESQISELKKQNNQLKDnieKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLK 294

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1237 IQVREsidgklpsTDQQESCSSTPGLEEPLFKATEQhhtqpvlesnlcpdwpshsedasalqggtsVAQIKAQLKEIEAE 1316
Cdd:TIGR04523  295 SEISD--------LNNQKEQDWNKELKSELKNQEKK------------------------------LEEIQNQISQNNKI 336

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1317 KVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTvsheaevHAESLQQKLESSQLQIaglehlRELQPKLDEL 1396
Cdd:TIGR04523  337 ISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKK-------ENQSYKQEIKNLESQI------NDLESKIQNQ 403

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1397 QKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALH---TQLEMQAKEHDERIKQLQVELCEMKQKPEEIGEE 1473
Cdd:TIGR04523  404 EKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTnqdSVKELIIKNLDNTRESLETQLKVLSRSINKIKQN 483

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1474 SRAKQQ---IQRKLQAALISRKEALKEN-KSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRL--ALLQEER 1547
Cdd:TIGR04523  484 LEQKQKelkSKEKELKKLNEEKKELEEKvKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELkkENLEKEI 563

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1548 DKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIES---LKSSKIAESTEWQEKHKELQKEYEILLQSYENV 1624
Cdd:TIGR04523  564 DEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEkekKISSLEKELEKAKKENEKLSSIIKNIKSKKNKL 643

                          490       500
                   ....*....|....*....|.
gi 1034632655 1625 SNEAERIQHVVEAVRQEKQEL 1645
Cdd:TIGR04523  644 KQEVKQIKETIKEIRNKWPEI 664
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
2099-2684 6.52e-04

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 45.44  E-value: 6.52e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2099 KLKKELQSNKESVKSQMKQKDEDLERRLEQAE--EKHLKEKKNMQEKLDALRREKVH-------LEETIGEIQVTLNKKD 2169
Cdd:PRK03918   193 ELIKEKEKELEEVLREINEISSELPELREELEklEKEVKELEELKEEIEELEKELESlegskrkLEEKIRELEERIEELK 272

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2170 KEVQQLQENLDStVTQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDaIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEEL 2249
Cdd:PRK03918   273 KEIEELEEKVKE-LKELKEKAEEYIKLSEFYEEYLDELREIEKRLSR-LEEEINGIEERIKELEEKEERLEELKKKLKEL 350

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2250 KINISRLEHDKQIWEskaqtevqlqqkvcdtlqgENKELLSQLEETRHlyHSSQNELAKLESELKSLKDQLTDLSNSLEK 2329
Cdd:PRK03918   351 EKRLEELEERHELYE-------------------EAKAKKEELERLKK--RLTGLTPEKLEKELEELEKAKEEIEEEISK 409

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2330 CKEQKGNLEGIIRQQEADIQNSKFSYEQLETdlqASRELTSRLHEEINMKEQKIISLLSGKEEAIQVAIAELRqqhdKEI 2409
Cdd:PRK03918   410 ITARIGELKKEIKELKKAIEELKKAKGKCPV---CGRELTEEHRKELLEEYTAELKRIEKELKEIEEKERKLR----KEL 482

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2410 KELENLLSqeeeeNIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQldsfvksmsslqndrdrivgDYQQLEERhlSI 2489
Cdd:PRK03918   483 RELEKVLK-----KESELIKLKELAEQLKELEEKLKKYNLEELEKKAE--------------------EYEKLKEK--LI 535

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2490 ILEKDQL-IQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAELIQyredlnqvitiKDSQQKQLLEVQLQQNKELENKY 2568
Cdd:PRK03918   536 KLKGEIKsLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEE-----------LGFESVEELEERLKELEPFYNEY 604

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2569 AKLEEKLKESeeanEDLRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTALQEegtlglyhaqlKVKEEEVHRLSALFS 2648
Cdd:PRK03918   605 LELKDAEKEL----EREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEK-----------KYSEEEYEELREEYL 669

                          570       580       590
                   ....*....|....*....|....*....|....*....
gi 1034632655 2649 SSQKRIAELEEELvcvqKEAAKKVGEIE---DKLKKELK 2684
Cdd:PRK03918   670 ELSRELAGLRAEL----EELEKRREEIKktlEKLKEELE 704
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 857-1106 6.54e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.14  E-value: 6.54e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  857 SSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEIsfsmTEKMVQLNEEKFSLGVEIKTLKEQLNL 936
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAAL----ARRIRALEQELAALEAELAELEKEIAE 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  937 LSRAEEAKKEQVEEDNEVSSGLKQNYDEMSPAGQISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELA 1016
Cdd:COG4942     95 LRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERA 174

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1017 NLKDESKKEiplsETERGEVEEDKENKEysekcvtskcqeieiylkQTISEKEVELQHIRKDLEEKLAAEEQFQALVKQM 1096
Cdd:COG4942    175 ELEALLAEL----EEERAALEALKAERQ------------------KLLARLEKELAELAAELAELQQEAEELEALIARL 232

                          250
                   ....*....|
gi 1034632655 1097 NQTLQDKTNQ 1106
Cdd:COG4942    233 EAEAAAAAER 242
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1902-2418 6.57e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 45.68  E-value: 6.57e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1902 EELSRVTKLKETAEEEKDDLE---------ERLMNQLAELNgsignYCQDVTD---AQIKNELLESEMKNLKKCVSELEE 1969
Cdd:COG4913    235 DDLERAHEALEDAREQIELLEpirelaeryAAARERLAELE-----YLRAALRlwfAQRRLELLEAELEELRAELARLEA 309

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1970 EKQQLVKEKTKVESEIR--KEYLEKIQGAQKEpgnkshakELQELLKEKQQEVKQLQKDCIRYQEKISALERTV----KA 2043
Cdd:COG4913    310 ELERLEARLDALREELDelEAQIRGNGGDRLE--------QLEREIERLERELEERERRRARLEALLAALGLPLpasaEE 381

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2044 LEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQKDEDL- 2122
Cdd:COG4913    382 FAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALRDALAEALGLDEAELp 461

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2123 -----------ERRLEQA--------------EEKHLK------EKKNMQEKLDALR-REKVHLEET--------IGEIQ 2162
Cdd:COG4913    462 fvgelievrpeEERWRGAiervlggfaltllvPPEHYAaalrwvNRLHLRGRLVYERvRTGLPDPERprldpdslAGKLD 541

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2163 VTLNKKDKEVQQ-LQENLD----STVTQLAAFTKSMSSL----QDDRDRVIDEAKKWERK----FS--DAIQSKEEEIRL 2227
Cdd:COG4913    542 FKPHPFRAWLEAeLGRRFDyvcvDSPEELRRHPRAITRAgqvkGNGTRHEKDDRRRIRSRyvlgFDnrAKLAALEAELAE 621

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2228 KEDNCSVLKDQLRQMSIHMEELKINISRLEH-DKQIWESKAQTEVQLQqkvcdtlqgenkelLSQLEETRHLYHSSQNEL 2306
Cdd:COG4913    622 LEEELAEAEERLEALEAELDALQERREALQRlAEYSWDEIDVASAERE--------------IAELEAELERLDASSDDL 687

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2307 AKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLE--TDLQASRELTSRLHEEINMKEQKII 2384
Cdd:COG4913    688 AALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEdlARLELRALLEERFAAALGDAVEREL 767

                          570       580       590
                   ....*....|....*....|....*....|....
gi 1034632655 2385 SllsgkeEAIQVAIAELRQQHDKEIKELENLLSQ 2418
Cdd:COG4913    768 R------ENLEERIDALRARLNRAEEELERAMRA 795
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
169-580 6.58e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 45.53  E-value: 6.58e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  169 QAQAEQPAQSSTEMEEFVMMKQQLQEKEEFISTLQAQLSQTQAE--------------QAAQVVREKDARFETQVRLHED 234
Cdd:COG4717     74 KELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREEleklekllqllplyQELEALEAELAELPERLEELEE 153

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  235 ELLQLVTQADVETEMQQKLRVLQRKLEEHEE--SLVGRAQVVDL------LQQELTAAEQRNQILSQQLQQMEAEHNTLR 306
Cdd:COG4717    154 RLEELRELEEELEELEAELAELQEELEELLEqlSLATEEELQDLaeeleeLQQRLAELEEELEEAQEELEELEEELEQLE 233

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  307 NTVETEREESKILLEKMELEVAERKLSFHNLQEEMHHLLEQFEQAGQAQAELESRYSALEQKHKAEMEEKTSHILSLQKT 386
Cdd:COG4717    234 NELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPAL 313

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  387 GQELQSACDALKDQNSKLLQDKNEQAVQSAQTIQQLEDQLQQKSKEISQflnrLPLQQHETASQTSFpdvynEGTQAVTE 466
Cdd:COG4717    314 EELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEE----LQLEELEQEIAALL-----AEAGVEDE 384

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  467 ENIASLQKRVVELENEKGALLLSSIELEELKAENEKLSSQITLLEAQNRTGEADREVSEIS--IVDIANKRSSSAEESGQ 544
Cdd:COG4717    385 EELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEELEELEEELEELEeeLEELREELAELEAELEQ 464

                          410       420       430
                   ....*....|....*....|....*....|....*.
gi 1034632655  545 DVLENTFSQKHKELSVLLLEMKEAQEEIAFLKLQLQ 580
Cdd:COG4717    465 LEEDGELAELLQELEELKAELRELAEEWAALKLALE 500
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1304-1775 6.74e-04

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 45.44  E-value: 6.74e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1304 AQIKAQLKEIEAEKVELELK---VSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQI 1380
Cdd:PRK03918   203 EEVLREINEISSELPELREElekLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKV 282

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1381 AGLEHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDlikalhtqLEMQAKEHDERIKQLQVEL 1460
Cdd:PRK03918   283 KELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEE--------KEERLEELKKKLKELEKRL 354

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1461 CEMKQKPEEIgEESRAKQQIQRKLQAALISR---------KEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNK 1531
Cdd:PRK03918   355 EELEERHELY-EEAKAKKEELERLKKRLTGLtpeklekelEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKK 433

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1532 EKDT--VLGRLaLLQEERDKLITEMDRSLLE-NQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESTE------ 1602
Cdd:PRK03918   434 AKGKcpVCGRE-LTEEHRKELLEEYTAELKRiEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQLKeleekl 512

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1603 ---WQEKHKELQKEYEILLQSYENVSNEAERIQHVVE---AVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEK 1676
Cdd:PRK03918   513 kkyNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEkleELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEE 592

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1677 MRKFAKSKQQKILELEEENDRLRAEVHPAGDTAKEcMETLLSSNASMKEELERVKMEYETLSKKF-----QSLMSEKDSL 1751
Cdd:PRK03918   593 RLKELEPFYNEYLELKDAEKELEREEKELKKLEEE-LDKAFEELAETEKRLEELRKELEELEKKYseeeyEELREEYLEL 671

                          490       500
                   ....*....|....*....|....
gi 1034632655 1752 SEEVQDLKHQIEGNVSKQANLEAT 1775
Cdd:PRK03918   672 SRELAGLRAELEELEKRREEIKKT 695
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1306-1773 6.74e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 45.40  E-value: 6.74e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1306 IKAQLKEIEAEKVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKtvSHEAEVHAESLQQKLESSQlqiaglEH 1385
Cdd:TIGR04523  251 TQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLN--NQKEQDWNKELKSELKNQE------KK 322

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1386 LRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKalhtQLEMQAKEHDERIKQLQVELCEMKQ 1465
Cdd:TIGR04523  323 LEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIE----KLKKENQSYKQEIKNLESQINDLES 398

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1466 KPEEIGEESrakQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQE 1545
Cdd:TIGR04523  399 KIQNQEKLN---QQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSR 475

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1546 ERDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKEL-QKEYEILLQSYENV 1624
Cdd:TIGR04523  476 SINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKIsDLEDELNKDDFELK 555

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1625 SNEaeriqhvVEAVRQEKQELYGKLRSTEANKKETEKQlqeaeqemeemkekmrkfaksKQQKILELEEENDRLRAEVhp 1704
Cdd:TIGR04523  556 KEN-------LEKEIDEKNKEIEELKQTQKSLKKKQEE---------------------KQELIDQKEKEKKDLIKEI-- 605

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1034632655 1705 agdtakecmETLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQANLE 1773
Cdd:TIGR04523  606 ---------EEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKEIRNKWPEII 665
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2677-2902 6.77e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.14  E-value: 6.77e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2677 DKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEELDEL 2756
Cdd:COG4942     23 AEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQ 102

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2757 KRKYDASLKELAQLKEQGLLNrerdALLSETAFsmnSTEENSLSHLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKA 2836
Cdd:COG4942    103 KEELAELLRALYRLGRQPPLA----LLLSPEDF---LDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAE 175

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1034632655 2837 MASLQNERDHLWNELEKFRKSEEGKQRSAAQpstspaEVQSLKKAMSSLQNDRDRLLKELKNLQQQ 2902
Cdd:COG4942    176 LEALLAELEEERAALEALKAERQKLLARLEK------ELAELAAELAELQQEAEELEALIARLEAE 235
PRK12704 PRK12704
phosphodiesterase; Provisional
 2068-2230 6.78e-04

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 45.15  E-value: 6.78e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2068 HRKKAQAELASFKVLLDDTQsEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLERR--LEQAEEKHLKEKKNMQEKLD 2145
Cdd:PRK12704    25 RKKIAEAKIKEAEEEAKRIL-EEAKKEAEAIKKEALLEAKEEIHKLRNEFEKELRERRneLQKLEKRLLQKEENLDRKLE 103

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2146 ALRREKVHLEETIGEiqvtLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQDD--RDRVIDEAK-KWERKFSDAIQSKE 2222
Cdd:PRK12704   104 LLEKREEELEKKEKE----LEQKQQELEKKEEELEELIEEQLQELERISGLTAEeaKEILLEKVEeEARHEAAVLIKEIE 179


                   ....*...
gi 1034632655 2223 EEIRLKED 2230
Cdd:PRK12704   180 EEAKEEAD 187
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1367-1596 7.45e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 45.29  E-value: 7.45e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1367 ESLQQKLESSQLQIAGLEHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALtkIQTEIIEQEDLIKALHTQLEmqa 1446
Cdd:COG4913    238 ERAHEALEDAREQIELLEPIRELAERYAAARERLAELEYLRAALRLWFAQRRLEL--LEAELEELRAELARLEAELE--- 312

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1447 kEHDERIKQLQVELCEMKQKPEEIGeeSRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQV 1526
Cdd:COG4913    313 -RLEARLDALREELDELEAQIRGNG--GDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEA 389

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1527 SAqnkekdtvlgRLALLQEERDKLITEMDRsllenqslssscesLKLALEGLTEDKEKLVKEIESLKSSK 1596
Cdd:COG4913    390 AA----------LLEALEEELEALEEALAE--------------AEAALRDLRRELRELEAEIASLERRK 435
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1055-1517 8.85e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 45.14  E-value: 8.85e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1055 QEIEIYLKQTISEKEVELQHIrKDLEEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEISENQAIIQKLITSNTDASDG 1134
Cdd:COG4717     53 KEADELFKPQGRKPELNLKEL-KELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLY 131

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1135 DSVALVKETVVISPPCtgssehwKPELEEKILALEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRL 1214
Cdd:COG4717    132 QELEALEAELAELPER-------LEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEEL 204

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1215 QEQFDEQSKENENIGDQLRQLQIQVRESIDGKLPSTDQQ--ESCSSTPGLEEPLFKATEQHHTQPVLESN---------- 1282
Cdd:COG4717    205 QQRLAELEEELEEAQEELEELEEELEQLENELEAAALEErlKEARLLLLIAAALLALLGLGGSLLSLILTiagvlflvlg 284

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1283 -LCPDWPSHSEDASALQGGTSVAQIKAQLKEIEAEKVELELKVSSTTSELTKKS-EEVFQLQEQINKQGLEIESLKtvsH 1360
Cdd:COG4717    285 lLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEElLELLDRIEELQELLREAEELE---E 361

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1361 EAEVHAESLQQKLESSQLQIAGLEHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEdlikalHT 1440
Cdd:COG4717    362 ELQLEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEE------LE 435

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1034632655 1441 QLEMQAKEHDERIKQLQVELCEMKQKPEEIgEESRAKQQIQRKLQAALISRKEALKENKSLQeelsLARGTIERLTK 1517
Cdd:COG4717    436 ELEEELEELEEELEELREELAELEAELEQL-EEDGELAELLQELEELKAELRELAEEWAALK----LALELLEEARE 507
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
2006-2530 9.21e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 45.03  E-value: 9.21e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2006 AKELQELLKEKQQEVKQLQKDCIRYQEKISALERtvkalefvqtesqkdleiTKENLAQAVEHRKKAQAELASFKVLLDD 2085
Cdd:PRK02224   201 EKDLHERLNGLESELAELDEEIERYEEQREQARE------------------TRDEADEVLEEHEERREELETLEAEIED 262

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2086 TQSEAARVladnlklKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLK--EKKNMQEKLDALRREKVHLEETIGEIQV 2163
Cdd:PRK02224   263 LRETIAET-------EREREELAEEVRDLRERLEELEEERDDLLAEAGLDdaDAEAVEARREELEDRDEELRDRLEECRV 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2164 TLNKKDKEVQQLQENLDstvtQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEEIRLKEDNCSVLKDQLRQMS 2243
Cdd:PRK02224   336 AAQAHNEEAESLREDAD----DLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAE 411

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2244 IHMEELKINISRLEhdkqiwESKAQTEVQLQQkVCDTLQgENKELLSQ---------LEETRHL--YHSSQNELAKLESE 2312
Cdd:PRK02224   412 DFLEELREERDELR------EREAELEATLRT-ARERVE-EAEALLEAgkcpecgqpVEGSPHVetIEEDRERVEELEAE 483

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2313 LKSLKDQLTDLSNSL-------------EKCKEQKGNLEGIIRQQEADIQNSKFSYEQ-------LETDLQASRELTSRL 2372
Cdd:PRK02224   484 LEDLEEEVEEVEERLeraedlveaedriERLEERREDLEELIAERRETIEEKRERAEElreraaeLEAEAEEKREAAAEA 563

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2373 HEEINMKEQKIISLlsgkeEAIQVAIAELRQQHDKeIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENI 2452
Cdd:PRK02224   564 EEEAEEAREEVAEL-----NSKLAELKERIESLER-IRTLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKR 637

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1034632655 2453 QQKAQLDSfvKSMSSLQNDRDRIVGDYQQLEERHLSIILEKDQLIQEAAAENNKLkEEIRGLRSHMDDLNSENAKLDA 2530
Cdd:PRK02224   638 ELEAEFDE--ARIEEAREDKERAEEYLEQVEEKLDELREERDDLQAEIGAVENEL-EELEELRERREALENRVEALEA 712
PLN02939 PLN02939
transferase, transferring glycosyl groups
 1444-1733 9.42e-04

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 45.28  E-value: 9.42e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1444 MQAKEHDERIKQLQVE-LCEMKQKPEE-IGEESRAKQQIQRKLQAALiSRKEAL-KENKSLQEELSLARGTIERLTKSLA 1520
Cdd:PLN02939   116 QTNSKDGEQLSDFQLEdLVGMIQNAEKnILLLNQARLQALEDLEKIL-TEKEALqGKINILEMRLSETDARIKLAAQEKI 194

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1521 DVESQVSAQNKEKDTVLGRLALLQEERDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKE---KLVKEIESLKSS-- 1595
Cdd:PLN02939   195 HVEILEEQLEKLRNELLIRGATEGLCVHSLSKELDVLKEENMLLKDDIQFLKAELIEVAETEErvfKLEKERSLLDASlr 274

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1596 ----KIAESTEWQEKHKELQkeYEILLQSYENVSNEAERIQHVVE---AVRQEKQELYGKLRSTEANKKETekqlqeaeq 1668
Cdd:PLN02939   275 elesKFIVAQEDVSKLSPLQ--YDCWWEKVENLQDLLDRATNQVEkaaLVLDQNQDLRDKVDKLEASLKEA--------- 343

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1034632655 1669 emeEMKEKMRKFAKSKQQKILELEEENDRLRAEVHPAGDTAKECMETLLSSNASMKEELERVKME 1733
Cdd:PLN02939   344 ---NVSKFSSYKVELLQQKLKLLEERLQASDHEIHSYIQLYQESIKEFQDTLSKLKEESKKRSLE 405
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 792-1023 9.66e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 44.37  E-value: 9.66e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  792 LLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKE 871
Cdd:COG4942     10 LLALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELE 89

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  872 LEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEI----------SFSMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAE 941
Cdd:COG4942     90 KEIAELRAELEAQKEELAELLRALYRLGRQPPLAlllspedfldAVRRLQYLKYLAPARREQAEELRADLAELAALRAEL 169

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  942 EAKKEQVEEDNEVSSGLKQNYDEMspagqisKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELANLKDE 1021
Cdd:COG4942    170 EAERAELEALLAELEEERAALEAL-------KAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242


                   ..
gi 1034632655 1022 SK 1023
Cdd:COG4942    243 TP 244
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1308-1771 9.80e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 44.76  E-value: 9.80e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1308 AQLKEIEAEKVELElkvsSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQiaglEHLR 1387
Cdd:COG4717     71 KELKELEEELKEAE----EKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALE----AELA 142

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1388 ELQPKLDELQ---KLISKKEEDVSYLSGQLSEKEAALTKI--QTEIIEQEDLIKAL--HTQLEMQAKEHDERIKQLQVEL 1460
Cdd:COG4717    143 ELPERLEELEerlEELRELEEELEELEAELAELQEELEELleQLSLATEEELQDLAeeLEELQQRLAELEEELEEAQEEL 222

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1461 CEMKQKPEEIGEESRAKQQIQR----KLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKekdtv 1536
Cdd:COG4717    223 EELEEELEQLENELEAAALEERlkeaRLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREK----- 297

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1537 lgrlALLQEERDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSS-KIAESTEWQEKHKELQKEYE 1615
Cdd:COG4717    298 ----ASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELlREAEELEEELQLEELEQEIA 373

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1616 ILLQSYeNVSNEAERIQHVVEAvrQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRkfAKSKQQKILELEEEN 1695
Cdd:COG4717    374 ALLAEA-GVEDEEELRAALEQA--EEYQELKEELEELEEQLEELLGELEELLEALDEEELEEE--LEELEEELEELEEEL 448

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1034632655 1696 DRLRAEVhpagDTAKECMETLLSSN--ASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQAN 1771
Cdd:COG4717    449 EELREEL----AELEAELEQLEEDGelAELLQELEELKAELRELAEEWAALKLALELLEEAREEYREERLPPVLERAS 522
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 46-301 9.82e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 44.93  E-value: 9.82e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655   46 TQEDVQERLAYAEQLVVELKDIIRQKDVQLQQKDEALQEERKAADNKIKKLKLHAKAKLTSLNKYIEEMKAQGGTVLPTE 125
Cdd:COG1196    271 ELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAE 350

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  126 PQSEEQLSKHDKSSTEEEMEIEKIKHKLQEKEELISTLQAQLTQAQAEQPAQsstemeefvmmkQQLQEKEEFISTLQAQ 205
Cdd:COG1196    351 EELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQL------------EELEEAEEALLERLER 418

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  206 LSQTQAEQAAQVVREKDARfetqvrlhEDELLQLVTQADVETEMQQKLRVLQRKLEEHEESLVGRAQVVDLLQQELTAAE 285
Cdd:COG1196    419 LEEELEELEEALAELEEEE--------EEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAA 490

                          250
                   ....*....|....*.
gi 1034632655  286 QRNQILSQQLQQMEAE 301
Cdd:COG1196    491 ARLLLLLEAEADYEGF 506
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
2099-2613 9.94e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 45.03  E-value: 9.94e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2099 KLKKELQSNKESVKSQMKQKDEDLERRLEQAE--EKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQ 2176
Cdd:PRK02224   199 KEEKDLHERLNGLESELAELDEEIERYEEQREqaRETRDEADEVLEEHEERREELETLEAEIEDLRETIAETEREREELA 278

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2177 EnldstvtQLAAFTKSMSSLQDDRDRVIDEAKkwerkFSDA-IQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELKINISR 2255
Cdd:PRK02224   279 E-------EVRDLRERLEELEEERDDLLAEAG-----LDDAdAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAES 346

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2256 LEHDKQIWESKAqtevqlqqkvcDTLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLK-------DQLTDLSNSLE 2328
Cdd:PRK02224   347 LREDADDLEERA-----------EELREEAAELESELEEAREAVEDRREEIEELEEEIEELRerfgdapVDLGNAEDFLE 415

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2329 KCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSrlheeinmkEQKIisllsgKEEAIQVAIAELRQQHDKE 2408
Cdd:PRK02224   416 ELREERDELREREAELEATLRTARERVEEAEALLEAGKCPEC---------GQPV------EGSPHVETIEEDRERVEEL 480

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2409 IKELENLLSQEEEENIVLEEEN--KKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERH 2486
Cdd:PRK02224   481 EAELEDLEEEVEEVEERLERAEdlVEAEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAA 560

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2487 LSIILEKDQLIQEAAAENNKL---KEEIRGLRSHMDDLnSENAKLDAELIQYREDLNQVITIKDsQQKQLLEVQLQQNKE 2563
Cdd:PRK02224   561 AEAEEEAEEAREEVAELNSKLaelKERIESLERIRTLL-AAIADAEDEIERLREKREALAELND-ERRERLAEKRERKRE 638

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1034632655 2564 LENKYAKLEEKLKESEEAN-----EDLRRSFNALQEEKQDLSKEIESLKVSISQL 2613
Cdd:PRK02224   639 LEAEFDEARIEEAREDKERaeeylEQVEEKLDELREERDDLQAEIGAVENELEEL 693
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 1815-2050 1.04e-03

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 44.92  E-value: 1.04e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1815 PSAKSANPAVSKDFSSHDEINNYLQQIDQLKERIAGLEEEKQKNK-----EFSQTLENEKNTLLSQISTKDGELKMLQEE 1889
Cdd:PRK05771    36 LKEELSNERLRKLRSLLTKLSEALDKLRSYLPKLNPLREEKKKVSvksleELIKDVEEELEKIEKEIKELEEEISELENE 115

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1890 VTKmnllnqqIQEELSRVTKLKETAEEEKDDLEERLMNQLAelnGSI--GNYCQDVTDAQIKNELLESEMKN-------- 1959
Cdd:PRK05771   116 IKE-------LEQEIERLEPWGNFDLDLSLLLGFKYVSVFV---GTVpeDKLEELKLESDVENVEYISTDKGyvyvvvvv 185

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1960 LKKCVSELEEE--KQQLVKEKTKVE---SEIRKEYLEKIQGAQKEpgnkshAKELQELLKEKQQEVKQLQKDCIRYQ--- 2031
Cdd:PRK05771   186 LKELSDEVEEElkKLGFERLELEEEgtpSELIREIKEELEEIEKE------RESLLEELKELAKKYLEELLALYEYLeie 259

                          250       260
                   ....*....|....*....|
gi 1034632655 2032 -EKISALERTVKALEFVQTE 2050
Cdd:PRK05771   260 lERAEALSKFLKTDKTFAIE 279
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
2284-2661 1.12e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 44.76  E-value: 1.12e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2284 ENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFS--YEQLETD 2361
Cdd:COG4717     75 ELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAELAELPerLEELEER 154

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2362 LQASREL---TSRLHEEINMKEQKIISLLSGKEEAIQVAIAELRQQHD---KEIKELENLLSQEEEENIVLEEeNKKAVD 2435
Cdd:COG4717    155 LEELRELeeeLEELEAELAELQEELEELLEQLSLATEEELQDLAEELEelqQRLAELEEELEEAQEELEELEE-ELEQLE 233

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2436 KTNQLMETLKTIKKENIQQKA------------QLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSIILEKDQLIQEAAAE 2503
Cdd:COG4717    234 NELEAAALEERLKEARLLLLIaaallallglggSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPAL 313

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2504 NNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDSQQKQLLEVQLQQNKElenkyakleEKLKESEEANE 2583
Cdd:COG4717    314 EELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIA---------ALLAEAGVEDE 384

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1034632655 2584 DLRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTALQEEGTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEEL 2661
Cdd:COG4717    385 EELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEELEELEEELEELEEELEELREELAELEAEL 462
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2890-3185 1.13e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 45.05  E-value: 1.13e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2890 DRLLKELKNLQQQYLQINQEITELHPLKAQLQEYQDKTKAFQIMQEELRQENLSWQHELHQLRMEKSSWEIHERRMKE-- 2967
Cdd:TIGR02168  232 LRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRErl 311

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2968 -----QYLMAISDKDQQLSHLQNLIRELRSSSSQTQPLKVQYQRQASpetsaspdgsqnlvyETELLRTQLNDSLKEIHQ 3042
Cdd:TIGR02168  312 anlerQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEA---------------ELEELEAELEELESRLEE 376

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 3043 KELRIQQLNSNFSQLLEEKNTLSIQLcdtsQSLRENQQHygdllnhcavLEKQVQELQavskekgplnidvapgapQEKN 3122
Cdd:TIGR02168  377 LEEQLETLRSKVAQLELQIASLNNEI----ERLEARLER----------LEDRRERLQ------------------QEIE 424

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1034632655 3123 GVHRKSDPEELREPQQSFSEAQQQLCNTRQEVNELRKLLEEERDQRVAAENALSVAEEQIRRL 3185
Cdd:TIGR02168  425 ELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQL 487
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1329-1761 1.21e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 44.76  E-value: 1.21e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1329 SELTKKSEEVFQLQEQINKQGL-EIESLKTVSHEAEVHAESLQQKLESSQLQIAGLEHLRELQPKLDELQKLISKKEEDV 1407
Cdd:COG4717     49 ERLEKEADELFKPQGRKPELNLkELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLL 128

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1408 SYLSgQLSEKEAALTKIQTEIIEQEDLIKALHtQLEMQAKEHDERIKQLQVELCEMKQKPEEigEESRAKQQIQRKLQAA 1487
Cdd:COG4717    129 PLYQ-ELEALEAELAELPERLEELEERLEELR-ELEEELEELEAELAELQEELEELLEQLSL--ATEEELQDLAEELEEL 204

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1488 LISRKEALKENKSLQEELSLARGTIERLTKSLADVESQvsAQNKEKDTVLGRLALLQEERDKLITEMDRSLLENQSLSSS 1567
Cdd:COG4717    205 QQRLAELEEELEEAQEELEELEEELEQLENELEAAALE--ERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLV 282

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1568 CESLKLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELyg 1647
Cdd:COG4717    283 LGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELE-- 360

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1648 klrsTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHPAGDTAKECMETLlsSNASMKEEL 1727
Cdd:COG4717    361 ----EELQLEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEAL--DEEELEEEL 434

                          410       420       430
                   ....*....|....*....|....*....|....
gi 1034632655 1728 ERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQ 1761
Cdd:COG4717    435 EELEEELEELEEELEELREELAELEAELEQLEED 468
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
682-1114 1.28e-03

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 44.65  E-value: 1.28e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  682 QDELERLKSQILELELNFHKAqeiyEKNLDEKAKEISNLNQLIEEFKKNADN-------NSSAFTALSEERDQLLSQVKE 754
Cdd:PRK02224   250 REELETLEAEIEDLRETIAET----EREREELAEEVRDLRERLEELEEERDDllaeaglDDADAEAVEARREELEDRDEE 325

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  755 L-SMVTELRAQVKQLEmNLAEAERQRRLDYESQTAHdnlLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIR 833
Cdd:PRK02224   326 LrDRLEECRVAAQAHN-EEAESLREDADDLEERAEE---LREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFG 401

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  834 SLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKK-----RDVE--TLQQTIEEKDQQVTEis 906
Cdd:PRK02224   402 DAPVDLGNAEDFLEELREERDELREREAELEATLRTARERVEEAEALLEAGKcpecgQPVEgsPHVETIEEDRERVEE-- 479

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  907 fsmtekmvqLNEEKFSLGVEIKTLKEQLNLLSRAEEAKK--EQVEEDNEVSSGLKQNYDEMSPAGQISKEELQHEFDLLK 984
Cdd:PRK02224   480 ---------LEAELEDLEEEVEEVEERLERAEDLVEAEDriERLEERREDLEELIAERRETIEEKRERAEELRERAAELE 550

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  985 KENEQRKRKLQAALINRKELLQRVSRLEEELANLKD--ESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIYLK 1062
Cdd:PRK02224   551 AEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKEriESLERIRTLLAAIADAEDEIERLREKREALAELNDERRERLA 630

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1034632655 1063 QT---ISEKEVELQHIRkdLEEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEI 1114
Cdd:PRK02224   631 EKrerKRELEAEFDEAR--IEEAREDKERAEEYLEQVEEKLDELREERDDLQAEI 683
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1575-1987 1.30e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 44.37  E-value: 1.30e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1575 LEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEillqSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEA 1654
Cdd:COG4717     48 LERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEE----EYAELQEELEELEEELEELEAELEELREELEKLEK 123

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1655 NKKETEKQLQEAEQEMEEMKEKMR-KFAKSKQQKILELEEENDRLRAEVHpagDTAKECMETLLSSNASMKEELERVKME 1733
Cdd:COG4717    124 LLQLLPLYQELEALEAELAELPERlEELEERLEELRELEEELEELEAELA---ELQEELEELLEQLSLATEEELQDLAEE 200

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1734 YETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQANLEATEKHDNQTN----------VTEEGTQSIPGETEEQDSLS 1803
Cdd:COG4717    201 LEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLllliaaallaLLGLGGSLLSLILTIAGVLF 280

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1804 MSTRPTCSESVPSAKSANPAVSK----DFSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLEnEKNTLLSQISTK 1879
Cdd:COG4717    281 LVLGLLALLFLLLAREKASLGKEaeelQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIE-ELQELLREAEEL 359

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1880 DGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAEEEKDDLEER--LMNQLAELNGSIGNYCQDVTDAQIKNELLESEM 1957
Cdd:COG4717    360 EEELQLEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELeeLEEQLEELLGELEELLEALDEEELEEELEELEE 439

                          410       420       430
                   ....*....|....*....|....*....|
gi 1034632655 1958 KnlkkcVSELEEEKQQLVKEKTKVESEIRK 1987
Cdd:COG4717    440 E-----LEELEEELEELREELAELEAELEQ 464
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 2013-2224 1.32e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 44.05  E-value: 1.32e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2013 LKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAAR 2092
Cdd:COG3883     18 IQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALYR 97

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2093 VLADNLKLKKELQS-------NKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTL 2165
Cdd:COG3883     98 SGGSVSYLDVLLGSesfsdflDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEAQQ 177

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1034632655 2166 NKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEE 2224
Cdd:COG3883    178 AEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAA 236
46 PHA02562
endonuclease subunit; Provisional
 1844-2133 1.33e-03

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 44.23  E-value: 1.33e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1844 LKERIAGLEEEkqknkefSQTLENEKNTLLSQISTKdgelKMLQEEVTKMNllNQQIQEELSRVTKLKETAEEEKDDLEE 1923
Cdd:PHA02562   172 NKDKIRELNQQ-------IQTLDMKIDHIQQQIKTY----NKNIEEQRKKN--GENIARKQNKYDELVEEAKTIKAEIEE 238

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1924 rLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEE------KQQLVKEKTKVESeirkeylekiqgaq 1997
Cdd:PHA02562   239 -LTDELLNLVMDIEDPSAALNKLNTAAAKIKSKIEQFQKVIKMYEKGgvcptcTQQISEGPDRITK-------------- 303

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1998 kepgNKSHAKELQ---ELLKEKQQEVKQLqkdciryqeKISALERTVKALEFvqtesQKDLEITKENLAQAVEHRKKAQA 2074
Cdd:PHA02562   304 ----IKDKLKELQhslEKLDTAIDELEEI---------MDEFNEQSKKLLEL-----KNKISTNKQSLITLVDKAKKVKA 365

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1034632655 2075 ELAsfkvllddtqseaarvladnlKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKH 2133
Cdd:PHA02562   366 AIE---------------------ELQAEFVDNAEELAKLQDELDKIVKTKSELVKEKY 403
PRK12704 PRK12704
phosphodiesterase; Provisional
 200-362 1.66e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 44.00  E-value: 1.66e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  200 STLQAQLSQTQaEQAAQVVreKDARFETQVRLHE------DELLQLVTQADVE-TEMQQKLRVLQRKLEEHEESLVGRAQ 272
Cdd:PRK12704    27 KIAEAKIKEAE-EEAKRIL--EEAKKEAEAIKKEalleakEEIHKLRNEFEKElRERRNELQKLEKRLLQKEENLDRKLE 103

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  273 VVDLLQQELTAAEQRNQILSQQLQQMEAEHNTLRNTVETE--------REESK-ILLEKMELEvaerklsfhnLQEEMHH 343
Cdd:PRK12704   104 LLEKREEELEKKEKELEQKQQELEKKEEELEELIEEQLQElerisgltAEEAKeILLEKVEEE----------ARHEAAV 173

                          170
                   ....*....|....*....
gi 1034632655  344 LLEQFEQAGQAQAELESRY 362
Cdd:PRK12704   174 LIKEIEEEAKEEADKKAKE 192
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2799-3087 1.74e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 44.16  E-value: 1.74e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2799 LSHLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKFRKSEEGKQRSAAQpstspaevqsL 2878
Cdd:COG1196    231 LLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELAR----------L 300

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2879 KKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELhplKAQLQEYQDKTKAFQIMQEELRQENLSWQHELHQLRMEKSSW 2958
Cdd:COG1196    301 EQDIARLEERRRELEERLEELEEELAELEEELEEL---EEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEA 377

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2959 EIHERRMKEQYLMAISDKDQQLSHLQNLIRELRSSSSQTQPLKVQYQRQASPETSASPdgsqnlvyETELLRTQLNDSLK 3038
Cdd:COG1196    378 EEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEE--------EEEEEEEALEEAAE 449

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*....
gi 1034632655 3039 EIHQKELRIQQLNSNFSQLLEEKNTLSIQLCDTSQSLRENQQHYGDLLN 3087
Cdd:COG1196    450 EEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLE 498
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 165-507 1.94e-03

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 44.17  E-value: 1.94e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  165 AQLTQAQA--EQPAQSSTEMEEFVMMKQQLQEKeefISTLQAQLSQTQ--AEQAAQVVREKD---ARFETQVRLHEDELL 237
Cdd:COG3096    316 EELSARESdlEQDYQAASDHLNLVQTALRQQEK---IERYQEDLEELTerLEEQEEVVEEAAeqlAEAEARLEAAEEEVD 392

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  238 QLVTQ-ADVetemQQKLRVLQRKLEEHEESL--VGRAQVV-DLLQQELTAAEQRNQILSQQLQQMEAEHNTLRNTVE--- 310
Cdd:COG3096    393 SLKSQlADY----QQALDVQQTRAIQYQQAVqaLEKARALcGLPDLTPENAEDYLAAFRAKEQQATEEVLELEQKLSvad 468

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  311 ---TEREESKILLEKMELEVaERKLSFHNLQE------EMHHLLEQFEQAGQAQAELESRysaLEQKHKA-----EMEEK 376
Cdd:COG3096    469 aarRQFEKAYELVCKIAGEV-ERSQAWQTAREllrryrSQQALAQRLQQLRAQLAELEQR---LRQQQNAerlleEFCQR 544

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  377 TSHILSLQKTGQELQSACDALKDQNSKLLQDKNEQAVQSAQTIQQLEDQLQQKSK------EISQFLNRLPLQQHETAsq 450
Cdd:COG3096    545 IGQQLDAAEELEELLAELEAQLEELEEQAAEAVEQRSELRQQLEQLRARIKELAArapawlAAQDALERLREQSGEAL-- 622

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1034632655  451 tsfpdvynEGTQAVTEEniaslqkRVVELENEKGAlllsSIELEELKAENEKLSSQI 507
Cdd:COG3096    623 --------ADSQEVTAA-------MQQLLEREREA----TVERDELAARKQALESQI 660
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2265-2474 1.95e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.60  E-value: 1.95e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2265 SKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQ 2344
Cdd:COG4942     30 EQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAEL 109

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2345 EADIQ-NSKFSYEQL----ETDLQASRELtsRLHEEINMKEQKIISLLSGKEEAIQVAIAELRQQHdKEIKELENLLSQE 2419
Cdd:COG4942    110 LRALYrLGRQPPLALllspEDFLDAVRRL--QYLKYLAPARREQAEELRADLAELAALRAELEAER-AELEALLAELEEE 186

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1034632655 2420 EEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDR 2474
Cdd:COG4942    187 RAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAE 241
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1492-2260 1.95e-03

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 44.19  E-value: 1.95e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1492 KEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMDRSLLENQSLSSSCESL 1571
Cdd:pfam02463  176 KKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIES 255

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1572 KLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRS 1651
Cdd:pfam02463  256 SKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKE 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1652 TEAN----KKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHPAGDTaKECMETLLSSNASMKEEL 1727
Cdd:pfam02463  336 EIEElekeLKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEE-LELKSEEEKEAQLLLELA 414

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1728 ERVKMEYETLSKK-------------FQSLMSEKDSLSEEVQDLKHQIEGNVSKQANLEATEKHdnqtNVTEEGTQSIPG 1794
Cdd:pfam02463  415 RQLEDLLKEEKKEeleileeeeesieLKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQ----LVKLQEQLELLL 490

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1795 ETEEQDSLSMSTRPTCSESVPSAKSANPAVSKDFSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLS 1874
Cdd:pfam02463  491 SRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRAL 570

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1875 QISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLK------ETAEEEKDDLEERLMNQLAELNGSIGNYCQDVTDAQI 1948
Cdd:pfam02463  571 TELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQldkatlEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRK 650

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1949 KNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCI 2028
Cdd:pfam02463  651 GVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEA 730

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2029 RYQEKISALERTVKALEFVQTEsqkDLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQSNK 2108
Cdd:pfam02463  731 QDKINEELKLLKQKIDEEEEEE---EKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALE 807

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2109 ESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIgeiqvTLNKKDKEVQQLQENLDSTVTQLAA 2188
Cdd:pfam02463  808 EELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELE-----RLEEEITKEELLQELLLKEEELEEQ 882

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1034632655 2189 FTKSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELKINISRLEHDK 2260
Cdd:pfam02463  883 KLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENN 954
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2442-2660 2.01e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.60  E-value: 2.01e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2442 ETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERhlsiILEKDQLIQEAAAENNKLKEEIRGLRSHMDDL 2521
Cdd:COG4942     20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERR----IAALARRIRALEQELAALEAELAELEKEIAEL 95

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2522 NSENAKLDAELIQ-----YREDLNQVITIKDSQQ------------KQLLEVQLQQNKELENKYAKLEEKLKESEEANED 2584
Cdd:COG4942     96 RAELEAQKEELAEllralYRLGRQPPLALLLSPEdfldavrrlqylKYLAPARREQAEELRADLAELAALRAELEAERAE 175

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1034632655 2585 LRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTALQeegtlglyhAQLKVKEEEVHRLSALFSSSQKRIAELEEE 2660
Cdd:COG4942    176 LEALLAELEEERAALEALKAERQKLLARLEKELAELA---------AELAELQQEAEELEALIARLEAEAAAAAER 242
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1332-1759 2.08e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 43.95  E-value: 2.08e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1332 TKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAE-SLQQKLESSQLQIAGLEHLRELQPKLDELQKLISKKEEDVSYL 1410
Cdd:pfam15921  408 TGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECQgQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAK 487

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1411 SGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQvelcEMKQKpeeiGEESRAKQQIQRKLQAALIS 1490
Cdd:pfam15921  488 KMTLESSERTVSDLTASLQEKERAIEATNAEITKLRSRVDLKLQELQ----HLKNE----GDHLRNVQTECEALKLQMAE 559

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1491 RKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMDRSLlenqslsSSCES 1570
Cdd:pfam15921  560 KDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEFKILKDKKDAKIRELEARV-------SDLEL 632

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1571 LKLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLR 1650
Cdd:pfam15921  633 EKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQSELEQTR 712

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1651 STEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHpagdtakecmeTLLSSNASMKEELERV 1730
Cdd:pfam15921  713 NTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKH-----------FLKEEKNKLSQELSTV 781

                          410       420
                   ....*....|....*....|....*....
gi 1034632655 1731 KMEYETLSKKFQSLMSEKDSLSEEVQDLK 1759
Cdd:pfam15921  782 ATEKNKMAGELEVLRSQERRLKEKVANME 810
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1061-1245 2.09e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.60  E-value: 2.09e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1061 LKQTISEKEVELQHIRKDLEEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEISENQAIIQKL---ITSNTDASDGDSV 1137
Cdd:COG4942     32 LQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELraeLEAQKEELAELLR 111

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1138 ALVKETVVISPPCTGSSEHWK-------------PELEEKILALEKEKEQLQkKLQEALTSRKAILKKAQEKERHLREEL 1204
Cdd:COG4942    112 ALYRLGRQPPLALLLSPEDFLdavrrlqylkylaPARREQAEELRADLAELA-ALRAELEAERAELEALLAELEEERAAL 190

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|.
gi 1034632655 1205 KQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVRESIDG 1245
Cdd:COG4942    191 EALKAERQKLLARLEKELAELAAELAELQQEAEELEALIAR 231
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1310-1777 2.13e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 43.90  E-value: 2.13e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1310 LKEIEAEKVELElkvssttsELTKKSEEVfqlQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLEHLREl 1389
Cdd:PRK03918   171 IKEIKRRIERLE--------KFIKRTENI---EELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKE- 238

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1390 qpKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALhTQLEMQAKEH-------------------- 1449
Cdd:PRK03918   239 --EIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKEL-KELKEKAEEYiklsefyeeyldelreiekr 315

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1450 ----DERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLqAALISRKEALKENKSLQEEL-----SLARGTIERLTKSLA 1520
Cdd:PRK03918   316 lsrlEEEINGIEERIKELEEKEERLEELKKKLKELEKRL-EELEERHELYEEAKAKKEELerlkkRLTGLTPEKLEKELE 394

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1521 DVESQVSAQNKEKDTVLGRLALLQEERDKLITEMDRsllenqsLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIA-E 1599
Cdd:PRK03918   395 ELEKAKEEIEEEISKITARIGELKKEIKELKKAIEE-------LKKAKGKCPVCGRELTEEHRKELLEEYTAELKRIEkE 467

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1600 STEWQEKHKELQKEyeilLQSYENVSNEAERIQHVVEAVRQEKqELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRK 1679
Cdd:PRK03918   468 LKEIEEKERKLRKE----LRELEKVLKKESELIKLKELAEQLK-ELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIK 542

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1680 FAKSKQQKILELEEENDRLRAEVHPAGDTAKECMETLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLK 1759
Cdd:PRK03918   543 SLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKELEPFYNEYLELKDAEKELEREEKELK 622

                          490
                   ....*....|....*...
gi 1034632655 1760 HQIEGNVSKQANLEATEK 1777
Cdd:PRK03918   623 KLEEELDKAFEELAETEK 640
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 278-1083 2.40e-03

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 43.81  E-value: 2.40e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  278 QQELTAAEQRNQILSQQLQQMEAEHNTLRNTVETEREESKILLEKMELEvaerklsfhnlQEEMHHLLEQFEQAGQAQAE 357
Cdd:pfam02463  215 LKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKE-----------EEKLAQVLKENKEEEKEKKL 283

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  358 LESRYSALEQKHKAEMEEKTSHILSLQKTGQELQsacdALKDQNSKLLQDKNEQAVQSAQTIQQLEDQLQQKSKEISQFL 437
Cdd:pfam02463  284 QEEELKLLAKEEEELKSELLKLERRKVDDEEKLK----ESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEE 359

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  438 NRLPLQQHETASQTSFPDVYNEGTQAVTEENIASLQKRVVELENEKGALLLSSIELEELKAENEKLSSQITLLEAQNRTG 517
Cdd:pfam02463  360 ELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESI 439

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  518 EADREVSEISIVDIANKRSSSAEESGQDVLENTFSQKHKELSVLLLEMKEAQEEIAFLKLQLQGKRAEEADHEVLDQKEM 597
Cdd:pfam02463  440 ELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDG 519

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  598 KQMEGEGIAPIKMKVFLEDTGQDFPLMPNEESSLPAVEKEQASTEHQSRTSEEISLNDAGVELKSTKQDGDKSLSAVPDI 677
Cdd:pfam02463  520 VGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEI 599

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  678 GQCHQDELERLKSQILELELNFHKAQEIYEKNLDEK------------AKEISNLNQLIEEFKKNADNNSSAFTALSEER 745
Cdd:pfam02463  600 DPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTklkesakakesgLRKGVSLEEGLAEKSEVKASLSELTKELLEIQ 679

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  746 DQLLSQVKELSMVTELRAQVKQLEMNLAEAERQRRLDYESQTAHDNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQF 825
Cdd:pfam02463  680 ELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKK 759

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  826 SEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQT-IEEKDQQVTE 904
Cdd:pfam02463  760 EEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEkIKEEELEELA 839

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  905 ISFSMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEMSPAGQISKEELQHEFDLLK 984
Cdd:pfam02463  840 LELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEI 919

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  985 KENEQRKRKLQAALINRKELLQRVSRLEEELANLKDES-KKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIYLKQ 1063
Cdd:pfam02463  920 EERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEeEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKER 999

                          810       820
                   ....*....|....*....|
gi 1034632655 1064 TISEKEVELQHIRKDLEEKL 1083
Cdd:pfam02463 1000 LEEEKKKLIRAIIEETCQRL 1019
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 2304-2929 2.70e-03

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 43.47  E-value: 2.70e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2304 NELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKI 2383
Cdd:TIGR04523   40 KKLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEIKNDKEQK 119

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2384 ISLlsgkeeaiqvaiaelrqqhDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVK 2463
Cdd:TIGR04523  120 NKL-------------------EVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEK 180

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2464 SMSSLQNDRDRIVGDYQQLEERhLSIILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVI 2543
Cdd:TIGR04523  181 EKLNIQKNIDKIKNKLLKLELL-LSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLK 259

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2544 TIKDSQQKQLLEVQLQQNKElenkyakleeklkeseeanedlrrsfnalQEEKQDLSKEIESLKVSISQLTRQvtalQEE 2623
Cdd:TIGR04523  260 DEQNKIKKQLSEKQKELEQN-----------------------------NKKIKELEKQLNQLKSEISDLNNQ----KEQ 306

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2624 GTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELVCVQKEAAKKVGEiEDKLKKELKHLHHDAGIMRNETETAEER 2703
Cdd:TIGR04523  307 DWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESE-NSEKQRELEEKQNEIEKLKKENQSYKQE 385

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2704 VAELARDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLK-EQGLLNRERDA 2782
Cdd:TIGR04523  386 IKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKElIIKNLDNTRES 465

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2783 L---LSETAFSMNSTEENslshLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNEL-------- 2851
Cdd:TIGR04523  466 LetqLKVLSRSINKIKQN----LEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKkekeskis 541

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2852 ---EKFRKSEEGKQRSA--AQPSTSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELHPLKAQLQEYQDK 2926
Cdd:TIGR04523  542 dleDELNKDDFELKKENleKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEK 621


                   ...
gi 1034632655 2927 TKA 2929
Cdd:TIGR04523  622 AKK 624
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2695-2922 2.73e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.21  E-value: 2.73e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2695 NETETAEERVAELARDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKEQg 2774
Cdd:COG4942     20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE- 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2775 lLNRERDALlsetafsmnsteENSLSHLEKLNQQllsKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKF 2854
Cdd:COG4942     99 -LEAQKEEL------------AELLRALYRLGRQ---PPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAEL 162

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1034632655 2855 RKSEEGKQRSAAQPSTSPAEVQSLKKAMSSLQNDRDRLLKEL----KNLQQQYLQINQEITELHPLKAQLQE 2922
Cdd:COG4942    163 AALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLekelAELAAELAELQQEAEELEALIARLEA 234
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
248-435 2.75e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 43.47  E-value: 2.75e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  248 EMQQKLRVLQRKLEEH--EESLVGRAQVVDLLQQELTAAEQRNQILSQQLQQMEAEHNTLRNTVETEREESKILLEKMEL 325
Cdd:COG3206    186 ELRKELEEAEAALEEFrqKNGLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDALPELLQSPVI 265

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  326 EVAERKLSfhNLQEEMHHLLEQF----EQAGQAQAELESRYSALEQKHKAEMEEKTSHILSLQKTGQELQSACDALKDQN 401
Cdd:COG3206    266 QQLRAQLA--ELEAELAELSARYtpnhPDVIALRAQIAALRAQLQQEAQRILASLEAELEALQAREASLQAQLAQLEARL 343

                          170       180       190
                   ....*....|....*....|....*....|....*.
gi 1034632655  402 SKLLQDKNEQAV--QSAQTIQQLEDQLQQKSKEISQ 435
Cdd:COG3206    344 AELPELEAELRRleREVEVARELYESLLQRLEEARL 379
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1839-2078 2.77e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 43.47  E-value: 2.77e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1839 QQIDQLKERIAGLEEE----KQKNKEFSqtLENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRvtKLKETA 1914
Cdd:COG3206    182 EQLPELRKELEEAEAAleefRQKNGLVD--LSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGS--GPDALP 257

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1915 EEEKDDLEERLMNQLAELNGSIGNYCQDVTDAQiknelleSEMKNLKkcvSELEEEKQQLVKEKTKVESEIRKEYLekiq 1994
Cdd:COG3206    258 ELLQSPVIQQLRAQLAELEAELAELSARYTPNH-------PDVIALR---AQIAALRAQLQQEAQRILASLEAELE---- 323

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1995 gaqkepGNKSHAKELQELLKEKQQEVKQLQKDciryQEKISALERtvkalefvqtesqkDLEITKENLAQAVEHRKKAQA 2074
Cdd:COG3206    324 ------ALQAREASLQAQLAQLEARLAELPEL----EAELRRLER--------------EVEVARELYESLLQRLEEARL 379


                   ....
gi 1034632655 2075 ELAS 2078
Cdd:COG3206    380 AEAL 383
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 831-1234 2.95e-03

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 43.56  E-value: 2.95e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  831 LIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKM------DQLLLEKKRDVETLQQTIEEKDQQVTE 904
Cdd:pfam05483  364 LLRTEQQRLEKNEDQLKIITMELQKKSSELEEMTKFKNNKEVELEELkkilaeDEKLLDEKKQFEKIAEELKGKEQELIF 443

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  905 ISFSMTEKMVQLNEEKFSLGV-EIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEMSPAGQISKEELQHEFDLL 983
Cdd:pfam05483  444 LLQAREKEIHDLEIQLTAIKTsEEHYLKEVEDLKTELEKEKLKNIELTAHCDKLLLENKELTQEASDMTLELKKHQEDII 523

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  984 --KKENEQRKRKLQAALINRKELLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIYL 1061
Cdd:pfam05483  524 ncKKQEERMLKQIENLEEKEMNLRDELESVREEFIQKGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQI 603

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1062 KQTISEKEvELQHIRKDLEEKLAAEE--------QFQALVKQMNQTLQDKTNQIDLLQAEISENQAIIQKLITSNTDASd 1133
Cdd:pfam05483  604 ENKNKNIE-ELHQENKALKKKGSAENkqlnayeiKVNKLELELASAKQKFEEIIDNYQKEIEDKKISEEKLLEEVEKAK- 681

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1134 gdsvALVKETVVISPPCTGSSEHwkpELEEKILALEKEKEQLQKKLQEALTSRKAILKKAQEKER---HLREELKQQKDD 1210
Cdd:pfam05483  682 ----AIADEAVKLQKEIDKRCQH---KIAEMVALMEKHKHQYDKIIEERDSELGLYKNKEQEQSSakaALEIELSNIKAE 754

                          410       420
                   ....*....|....*....|....
gi 1034632655 1211 YNRLQEQFDEQSKENENIGDQLRQ 1234
Cdd:pfam05483  755 LLSLKKQLEIEKEEKEKLKMEAKE 778
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1832-2065 2.98e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 42.89  E-value: 2.98e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1832 DEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKmnlLNQQIQEelsRVTKLK 1911
Cdd:COG3883     16 PQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAE---AEAEIEE---RREELG 89

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1912 ETAEEEKddLEERLMNQLAELNGSignycQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEirkeyLE 1991
Cdd:COG3883     90 ERARALY--RSGGSVSYLDVLLGS-----ESFSDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAK-----LA 157

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1034632655 1992 KIQGAQKEpgNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQA 2065
Cdd:COG3883    158 ELEALKAE--LEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAA 229
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 48-378 3.01e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 43.52  E-value: 3.01e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655   48 EDVQERLAYAEQLVVELKDIIR---QKDVQLQQKDEALQEERKAADNKIKKLKLHAKAKLTSLNKYIEEMKAQGGTVLPT 124
Cdd:TIGR02169  691 SSLQSELRRIENRLDELSQELSdasRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEEL 770

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  125 EPQ-SEEQLSKHDKSSTEEEMEIEKIKHKLQEKEELISTLQAQLtqAQAEQPAQSSTEMEEFvmMKQQLQEKEEFISTLQ 203
Cdd:TIGR02169  771 EEDlHKLEEALNDLEARLSHSRIPEIQAELSKLEEEVSRIEARL--REIEQKLNRLTLEKEY--LEKEIQELQEQRIDLK 846

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  204 AQLSQTQAEQAAqvVREKDARFETQVRLHEDELLQLVTQ-ADVETE---MQQKLRVLQRKLEEHEESlvgraqvVDLLQQ 279
Cdd:TIGR02169  847 EQIKSIEKEIEN--LNGKKEELEEELEELEAALRDLESRlGDLKKErdeLEAQLRELERKIEELEAQ-------IEKKRK 917

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  280 ELTAAEQRNQILSQQLQQMEAEHNTLRNTVETEREESKILLEKMELEVAERKLSFHNLqeemhhlleqfeQAGQAQAELE 359
Cdd:TIGR02169  918 RLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDVQAELQRVEEEIRALEPVNM------------LAIQEYEEVL 985

                          330
                   ....*....|....*....
gi 1034632655  360 SRYSALEQKHKAEMEEKTS 378
Cdd:TIGR02169  986 KRLDELKEKRAKLEEERKA 1004
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 659-1235 3.08e-03

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 43.50  E-value: 3.08e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  659 ELKSTKQDGDKSLSAVPDIGQCHQDELERLKSQILELELNFHKAqeIYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAF 738
Cdd:TIGR01612 1119 DIKNLDQKIDHHIKALEEIKKKSENYIDEIKAQINDLEDVADKA--ISNDDPEEIEKKIENIVTKIDKKKNIYDEIKKLL 1196

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  739 TALSE-ERDQL-LSQVKELSMVTELRAQVKQLEmNLAEAERQRRLDYESQTAH----DNLLTEQIHSLSIEAKSKDVK-- 810
Cdd:TIGR01612 1197 NEIAEiEKDKTsLEEVKGINLSYGKNLGKLFLE-KIDEEKKKSEHMIKAMEAYiedlDEIKEKSPEIENEMGIEMDIKae 1275

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  811 IEVLQNELDDVQLQFSEQSTLIRSLqSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVET 890
Cdd:TIGR01612 1276 METFNISHDDDKDHHIISKKHDENI-SDIREKSLKIIEDFSEESDINDIKKELQKNLLDAQKHNSDINLYLNEIANIYNI 1354

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  891 LQ-QTIEEKDQQVTEISFSMTEKMVQLNEEKFSLGVEIKTLKEQLNLlsRAEEAKKEQVEEDNEVSsGLKQNYDEMSPAG 969
Cdd:TIGR01612 1355 LKlNKIKKIIDEVKEYTKEIEENNKNIKDELDKSEKLIKKIKDDINL--EECKSKIESTLDDKDID-ECIKKIKELKNHI 1431

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  970 QISKEELQHEFDLLKKENEQrkrklqaALINRKELLQRVSRLEEELANLKDESKKEIPLSetergeVEEDKENKEYSEKC 1049
Cdd:TIGR01612 1432 LSEESNIDTYFKNADENNEN-------VLLLFKNIEMADNKSQHILKIKKDNATNDHDFN------INELKEHIDKSKGC 1498

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1050 VTskcqEIEIYLKQTISEKEVELQHiRKDLEE------KLAAEEQFQALVKQMNQTL---QDKTNQIdLLQAEISENQ-- 1118
Cdd:TIGR01612 1499 KD----EADKNAKAIEKNKELFEQY-KKDVTEllnkysALAIKNKFAKTKKDSEIIIkeiKDAHKKF-ILEAEKSEQKik 1572

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1119 AIIQKLITSNTDASDGD--SVALVKETVVISPpctgssehwkpeLEEKILALEkekeQLQKKLQEALTSRKAILKKAQEK 1196
Cdd:TIGR01612 1573 EIKKEKFRIEDDAAKNDksNKAAIDIQLSLEN------------FENKFLKIS----DIKKKINDCLKETESIEKKISSF 1636

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|
gi 1034632655 1197 ERHLRE-ELKQQKDDYNRLQEQFDEQSKENENIGDQLRQL 1235
Cdd:TIGR01612 1637 SIDSQDtELKENGDNLNSLQEFLESLKDQKKNIEDKKKEL 1676
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2402-2619 3.16e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.83  E-value: 3.16e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2402 RQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDY-- 2479
Cdd:COG4942     29 LEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELae 108

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2480 -----QQLEERHLSIILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLdaeliqyrEDLNQVITIKDSQQKQLL 2554
Cdd:COG4942    109 llralYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAEL--------AALRAELEAERAELEALL 180

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1034632655 2555 EVQLQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTA 2619
Cdd:COG4942    181 AELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
COG5022 COG5022
Myosin heavy chain [General function prediction only];
1956-2388 3.20e-03

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 43.53  E-value: 3.20e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1956 EMKNLKKCVSEL--EEEKQQLVKEKTKVESEIRKEYLekIQGAQKEPGNKSHAKEL--QELLKEKQQEVKQLQKDCIRYQ 2031
Cdd:COG5022    811 EYRSYLACIIKLqkTIKREKKLRETEEVEFSLKAEVL--IQKFGRSLKAKKRFSLLkkETIYLQSAQRVELAERQLQELK 888

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2032 E---KISALERTVKALEFVQTESQKDLEitkENLAQAVEHRKKAQAELasfKVLLDDTQSEaarvladnlklkkeLQSNK 2108
Cdd:COG5022    889 IdvkSISSLKLVNLELESEIIELKKSLS---SDLIENLEFKTELIARL---KKLLNNIDLE--------------EGPSI 948

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2109 ESVKSQMKQKDEDLERRLEQAEEkhlkEKKNMQEKLDALRREkvhleetigeiqvtLNKKDKEVQQLQENLDSTVTQLAA 2188
Cdd:COG5022    949 EYVKLPELNKLHEVESKLKETSE----EYEDLLKKSTILVRE--------------GNKANSELKNFKKELAELSKQYGA 1010

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2189 FTKSMSSLQDdRDRVIDEAKKWERKFSDaiQSKEEEIRLKEDNC-SVLKDQLRQMSIHMEELKINISRLEHDKQIWESKA 2267
Cdd:COG5022   1011 LQESTKQLKE-LPVEVAELQSASKIISS--ESTELSILKPLQKLkGLLLLENNQLQARYKALKLRRENSLLDDKQLYQLE 1087

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2268 QTEVQLQQKVCDTLQGENKELLSQLEETRHLYHSSQNELAKLESElKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQ---- 2343
Cdd:COG5022   1088 STENLLKTINVKDLEVTNRNLVKPANVLQFIVAQMIKLNLLQEIS-KFLSQLVNTLEPVFQKLSVLQLELDGLFWEanle 1166

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*
gi 1034632655 2344 QEADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKIISLLS 2388
Cdd:COG5022   1167 ALPSPPPFAALSEKRLYQSALYDEKSKLSSSEVNDLKNELIALFS 1211
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 152-440 3.27e-03

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 43.40  E-value: 3.27e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  152 KLQEKEELISTLQAQLTQAQAEQPAQSSTEMEEFVMMKQQLQEKEEFISTLQAQLS---------QTQAEQAAQVVREKD 222
Cdd:COG3096    344 RQQEKIERYQEDLEELTERLEEQEEVVEEAAEQLAEAEARLEAAEEEVDSLKSQLAdyqqaldvqQTRAIQYQQAVQALE 423

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  223 aRFETQVRLH-------EDELLQLVTQADVETE----MQQKLRVLQRKLEEHEESL---------VGRAQVVDLLQQEL- 281
Cdd:COG3096    424 -KARALCGLPdltpenaEDYLAAFRAKEQQATEevleLEQKLSVADAARRQFEKAYelvckiageVERSQAWQTARELLr 502

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  282 TAAEQRNQIlsQQLQQMEAEHNTLRNTVEtEREESKILLEKMELEVAERKLSFHNLQEEMHHLLEQFEQAGQAQAELESR 361
Cdd:COG3096    503 RYRSQQALA--QRLQQLRAQLAELEQRLR-QQQNAERLLEEFCQRIGQQLDAAEELEELLAELEAQLEELEEQAAEAVEQ 579

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  362 YSALEQkhkaEMEEKTSHILSLQKTG---QELQSACDALKDQ------NSKLLQDKNEQAVQSAQTIQQLEDQLQQKSKE 432
Cdd:COG3096    580 RSELRQ----QLEQLRARIKELAARApawLAAQDALERLREQsgealaDSQEVTAAMQQLLEREREATVERDELAARKQA 655


                   ....*...
gi 1034632655  433 ISQFLNRL 440
Cdd:COG3096    656 LESQIERL 663
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 2106-2718 3.41e-03

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 43.29  E-value: 3.41e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2106 SNKESVKSQMKQKDEDLERRLEqaEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQvTLNKKDKEVQQLQENLDSTV-T 2184
Cdd:pfam12128  207 EDDGVVPPKSRLNRQQVEHWIR--DIQAIAGIMKIRPEFTKLQQEFNTLESAELRLS-HLHFGYKSDETLIASRQEERqE 283

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2185 QLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEEIRLKEDNCSVLKD-----------QLRQMSIHMEELKINI 2253
Cdd:pfam12128  284 TSAELNQLLRTLDDQWKEKRDELNGELSAADAAVAKDRSELEALEDQHGAFLDadietaaadqeQLPSWQSELENLEERL 363

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2254 SRLEHDKQIWESKAQTEVQLQQKVC-DTLQGENKELLSQLEETRHLYHSSQNELAKLESELKS-LKDQLTDLSNSLEKCK 2331
Cdd:pfam12128  364 KALTGKHQDVTAKYNRRRSKIKEQNnRDIAGIKDKLAKIREARDRQLAVAEDDLQALESELREqLEAGKLEFNEEEYRLK 443

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2332 EQKGNLEGIIRQQEADiqnskfsyEQLETDLQASRELTSRLHEEINMKEQKIisllsgkeEAIQVAIAELRQQHDKEIKE 2411
Cdd:pfam12128  444 SRLGELKLRLNQATAT--------PELLLQLENFDERIERAREEQEAANAEV--------ERLQSELRQARKRRDQASEA 507

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2412 LENLLSQEEEENIVLEEENKKAVDKTNQLMETLKtikKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERHL-SII 2490
Cdd:pfam12128  508 LRQASRRLEERQSALDELELQLFPQAGTLLHFLR---KEAPDWEQSIGKVISPELLHRTDLDPEVWDGSVGGELNLyGVK 584

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2491 LEKDQL-IQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAELIQYredlnqvitikdsqqkqllevqlqqNKELENKYA 2569
Cdd:pfam12128  585 LDLKRIdVPEWAASEEELRERLDKAEEALQSAREKQAAAEEQLVQA-------------------------NGELEKASR 639

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2570 KLEEKLKESEEANEDLRRSFNALQEEKQDLSKEIESLK----VSISQLTRQVTALQEEGTLGLYHAQLKVKEEEVHRLS- 2644
Cdd:pfam12128  640 EETFARTALKNARLDLRRLFDEKQSEKDKKNKALAERKdsanERLNSLEAQLKQLDKKHQAWLEEQKEQKREARTEKQAy 719

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1034632655 2645 --ALFSSSQKRIAELEEELVCVQKEAAKKVGEIEDKLKKELKHLHHDagimrnetetaEERVAELARDLVEMEQKL 2718
Cdd:pfam12128  720 wqVVEGALDAQLALLKAAIAARRSGAKAELKALETWYKRDLASLGVD-----------PDVIAKLKREIRTLERKI 784
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 457-1244 3.45e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 43.12  E-value: 3.45e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  457 YNEGTQAVTEENIASLQKRVVELENEKGALLLS----SIELEELKAENEKLSSQITLLEAQNrtGEADREVSEIsivdia 532
Cdd:TIGR02168  215 YKELKAELRELELALLVLRLEELREELEELQEElkeaEEELEELTAELQELEEKLEELRLEV--SELEEEIEEL------ 286

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  533 nkrsssaeesgQDVLENTfSQKHKELSVLLLEMKEAQEEIAFLKLQLQGKRAEEADHEVLDQKEMKQMEGEgiapikmkv 612
Cdd:TIGR02168  287 -----------QKELYAL-ANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEK--------- 345

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  613 fLEDTGQDFPLMPNEESSLPAVEKEQASTEHQSRTsEEISLNDAGVELKSTKQDGDKSLSAVPDIGQCHQDELERLKSQI 692
Cdd:TIGR02168  346 -LEELKEELESLEAELEELEAELEELESRLEELEE-QLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEI 423

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  693 LELELNFHKAQ-EIYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLSQVKELSMVTELRAQVKQLEMN 771
Cdd:TIGR02168  424 EELLKKLEEAElKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEG 503

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  772 LAEAERQRRLDYESQTAHDNLLTEQIH-----SLSIEA----KSKDVKIEVLQNELDDVQLQFSEQS------------- 829
Cdd:TIGR02168  504 FSEGVKALLKNQSGLSGILGVLSELISvdegyEAAIEAalggRLQAVVVENLNAAKKAIAFLKQNELgrvtflpldsikg 583

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  830 TLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRdvETLQQTIEEKDQQVTEISFSM 909
Cdd:TIGR02168  584 TEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKK--LRPGYRIVTLDGDLVRPGGVI 661

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  910 TEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEdnevSSGLKQNYDEMSPAGQISKEELQHEFDLLKKENEQ 989
Cdd:TIGR02168  662 TGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAE----LRKELEELEEELEQLRKELEELSRQISALRKDLAR 737

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  990 RKRKLQAalinrkeLLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIyLKQTISEKE 1069
Cdd:TIGR02168  738 LEAEVEQ-------LEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKA-LREALDELR 809

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1070 VELQHIRKDLEEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEISENQAIIQKLITSNTDASDGDSVALVKETVVISPP 1149
Cdd:TIGR02168  810 AELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEAL 889

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1150 CTGSSEhwKPELEEKILALEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIG 1229
Cdd:TIGR02168  890 ALLRSE--LEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDE 967

                          810
                   ....*....|....*
gi 1034632655 1230 DQLRQLQIQVRESID 1244
Cdd:TIGR02168  968 EEARRRLKRLENKIK 982
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
152-601 3.47e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 43.22  E-value: 3.47e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  152 KLQEKEELISTLQAQLTQAQAEQPAQSSTEmEEFVMMKQQLQEKEEFISTLQAQLSQTQAEQAAQVVREKDARFETQVRL 231
Cdd:COG4717     72 ELKELEEELKEAEEKEEEYAELQEELEELE-EELEELEAELEELREELEKLEKLLQLLPLYQELEALEAELAELPERLEE 150

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  232 HEDELLQLVTQADVETEMQQKLRVLQRKLEEHEE--SLVGRAQVVDL------LQQELTAAEQRNQILSQQLQQMEAEHN 303
Cdd:COG4717    151 LEERLEELRELEEELEELEAELAELQEELEELLEqlSLATEEELQDLaeeleeLQQRLAELEEELEEAQEELEELEEELE 230

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  304 TLRNTVETEREESKILLEKMELEVAERKLSFHNLQEEMHHLLEQFEQAGQAQAELESRYSALEQKHKAEMEEKTSHILSL 383
Cdd:COG4717    231 QLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQAL 310

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  384 QKTGQELQSACDALKDQNSKLLQDKNEQAVQSAQTIQQLEDQLQQKSKEISQflnrLPLQQHETASQTSFpdvynEGTQA 463
Cdd:COG4717    311 PALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEE----LQLEELEQEIAALL-----AEAGV 381

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  464 VTEENIASLQKRVVELENEKGALLLSSIELEELKAENEKLSSQITLLEAQNRTGEADREVSEISIvdiankrsssaeesg 543
Cdd:COG4717    382 EDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEELEELEEELEELEE--------------- 446

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1034632655  544 qdvlentfsqkhkelsvlllEMKEAQEEIAFLKLQLQGKRAEEADHEVLDQKEMKQME 601
Cdd:COG4717    447 --------------------ELEELREELAELEAELEQLEEDGELAELLQELEELKAE 484
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
 1160-1236 3.49e-03

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 43.15  E-value: 3.49e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1160 ELEEKILALEKEKEQLQKKLQEALTSRKAILKK----AQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQL 1235
Cdd:COG0542    415 ELERRLEQLEIEKEALKKEQDEASFERLAELRDelaeLEEELEALKARWEAEKELIEEIQELKEELEQRYGKIPELEKEL 494


                   .
gi 1034632655 1236 Q 1236
Cdd:COG0542    495 A 495
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 1913-2144 3.71e-03

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 42.99  E-value: 3.71e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1913 TAEEEKDDLEERLMN----QLAELNGSIGNYcqdvtdaqiKNELLESEMKNLKKCVSELEEEKQqlvKEKTKVESEIRKE 1988
Cdd:PRK05771    13 TLKSYKDEVLEALHElgvvHIEDLKEELSNE---------RLRKLRSLLTKLSEALDKLRSYLP---KLNPLREEKKKVS 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1989 YLEKIQGAQKEPGNKShakELQELLKEKQQEVKQLQKDCIRYQEKISALE---------------RTVKA---------- 2043
Cdd:PRK05771    81 VKSLEELIKDVEEELE---KIEKEIKELEEEISELENEIKELEQEIERLEpwgnfdldlslllgfKYVSVfvgtvpedkl 157

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2044 LEFVQTESQKDLEITKEN-------LAQAVEHRKKAQAELASFKVLLDDTQSE--AARVLADNLKLKKELQSNKESVKSQ 2114
Cdd:PRK05771   158 EELKLESDVENVEYISTDkgyvyvvVVVLKELSDEVEEELKKLGFERLELEEEgtPSELIREIKEELEEIEKERESLLEE 237

                          250       260       270
                   ....*....|....*....|....*....|..
gi 1034632655 2115 MKQKDEDLERRLEQAEEK--HLKEKKNMQEKL 2144
Cdd:PRK05771   238 LKELAKKYLEELLALYEYleIELERAEALSKF 269
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1379-1560 4.01e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 41.83  E-value: 4.01e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1379 QIAGLEHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKalhtQLEMQAKEHDERIKQLQV 1458
Cdd:COG1579      5 DLRALLDLQELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIK----RLELEIEEVEARIKKYEE 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1459 ELcEMKQKPEEIGEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTvlg 1538
Cdd:COG1579     81 QL-GNVRNNKEYEALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEA--- 156

                          170       180
                   ....*....|....*....|..
gi 1034632655 1539 RLALLQEERDKLITEMDRSLLE 1560
Cdd:COG1579    157 ELEELEAEREELAAKIPPELLA 178
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 708-1245 4.02e-03

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 43.09  E-value: 4.02e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  708 KNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLSQVKELsmvtelRAQVKQLEMNLAEAERQRrLDYESQT 787
Cdd:TIGR04523  117 EQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDL------KKQKEELENELNLLEKEK-LNIQKNI 189

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  788 AHDNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQAL 867
Cdd:TIGR04523  190 DKIKNKLLKLELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQL 269

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  868 SQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNEEKF---------------SLGVEIKTLKE 932
Cdd:TIGR04523  270 SEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEQDWNKELKSELKNQEKKLeeiqnqisqnnkiisQLNEQISQLKK 349

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  933 QLNLLSRAEEAKKEQVEEDNEVSSGLK---QNYDEMSPAGQISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVS 1009
Cdd:TIGR04523  350 ELTNSESENSEKQRELEEKQNEIEKLKkenQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIE 429

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1010 RLEEELANLKDESKkeiplsetergeveeDKENKEYSEKCVTSKCQEIEIYLKQTISEKEVELQHIRKDLEEKLAAEEQF 1089
Cdd:TIGR04523  430 RLKETIIKNNSEIK---------------DLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSK 494

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1090 QALVKQMNQTLQDKTNQIDLLQAEISENQAIIQKL----ITSNTDASDGDSVALVKETVVISPPCTGSSEHWKPELEE-- 1163
Cdd:TIGR04523  495 EKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLesekKEKESKISDLEDELNKDDFELKKENLEKEIDEKNKEIEElk 574

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1164 -KILALEKEKEQLQKKLQEALTSRKAILKKAQEKERhLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVRES 1242
Cdd:TIGR04523  575 qTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEK-KISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKET 653


                   ...
gi 1034632655 1243 IDG 1245
Cdd:TIGR04523  654 IKE 656
PRK09039 PRK09039
peptidoglycan -binding protein;
2692-2826 4.11e-03

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 42.26  E-value: 4.11e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2692 IMRNETETAEERVAELARDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLK 2771
Cdd:PRK09039    43 FLSREISGKDSALDRLNSQIAELADLLSLERQGNQDLQDSVANLRASLSAAEAERSRLQALLAELAGAGAAAEGRAGELA 122

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1034632655 2772 EQglLNRERDalLSETAfsmnsteensLSHLEKLNQQLLSKDEQLLHLSSQLEDS 2826
Cdd:PRK09039   123 QE--LDSEKQ--VSARA----------LAQVELLNQQIAALRRQLAALEAALDAS 163
PRK01156 PRK01156
chromosome segregation protein; Provisional
 2282-2913 4.26e-03

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 42.97  E-value: 4.26e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2282 QGENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLegiiRQQEADIQNSKFSYEQLETD 2361
Cdd:PRK01156   137 QGEMDSLISGDPAQRKKILDEILEINSLERNYDKLKDVIDMLRAEISNIDYLEEKL----KSSNLELENIKKQIADDEKS 212

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2362 LQASRELTSRLHEEINMKEQKIISLLSGKEEAIqvAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLM 2441
Cdd:PRK01156   213 HSITLKEIERLSIEYNNAMDDYNNLKSALNELS--SLEDMKNRYESEIKTAESDLSMELEKNNYYKELEERHMKIINDPV 290

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2442 ETLKTIKKENIQQKAQLDSFVKSMSSLQNDrdrivgdyqqleerhlsiiLEKDQLIQEAAAENNKLKEEIRGLRSHMDDL 2521
Cdd:PRK01156   291 YKNRNYINDYFKYKNDIENKKQILSNIDAE-------------------INKYHAIIKKLSVLQKDYNDYIKKKSRYDDL 351

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2522 NSENAKLDAELIQYREDLNQVITIKDSQQkqllevqlQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSK 2601
Cdd:PRK01156   352 NNQILELEGYEMDYNSYLKSIESLKKKIE--------EYSKNIERMSAFISEILKIQEIDPDAIKKELNEINVKLQDISS 423

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2602 EIESLKVSISQLTRQVTALQEEGTLGLYHAQLKV-----KEEEVHRLSALFSSSQKRiaeLEEELVCVQKEAAKkvgeIE 2676
Cdd:PRK01156   424 KVSSLNQRIRALRENLDELSRNMEMLNGQSVCPVcgttlGEEKSNHIINHYNEKKSR---LEEKIREIEIEVKD----ID 496

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2677 DKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVtKENKGLTAQIQSFGRSMsslqnsrdhaneELDEL 2756
Cdd:PRK01156   497 EKIVDLKKRKEYLESEEINKSINEYNKIESARADLEDIKIKINEL-KDKHDKYEEIKNRYKSL------------KLEDL 563

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2757 KRKYDASLKELAQLKEQGLLN-----RERDALLSETAFSMNSTEENsLSHLEKLNQQLLSKDEQLLHLssqLEDSYNQVQ 2831
Cdd:PRK01156   564 DSKRTSWLNALAVISLIDIETnrsrsNEIKKQLNDLESRLQEIEIG-FPDDKSYIDKSIREIENEANN---LNNKYNEIQ 639

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2832 SFSKAMASLQNERDHLWNELEKFRKSEEGKQRSAAQPSTSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEIT 2911
Cdd:PRK01156   640 ENKILIEKLRGKIDNYKKQIAEIDSIIPDLKEITSRINDIEDNLKKSRKALDDAKANRARLESTIEILRTRINELSDRIN 719


                   ..
gi 1034632655 2912 EL 2913
Cdd:PRK01156   720 DI 721
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 688-1479 4.37e-03

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 43.11  E-value: 4.37e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  688 LKSQILELELNFHKAQEIYEKNLDEkAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLSQVKELSMVTELRAQVKQ 767
Cdd:TIGR00606  222 IRDQITSKEAQLESSREIVKSYENE-LDPLKNRLKEIEHNLSKIMKLDNEIKALKSRKKQMEKDNSELELKMEKVFQGTD 300

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  768 LEMNLAEAERQRRLDYESQTAHDnlLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEV- 846
Cdd:TIGR00606  301 EQLNDLYHNHQRTVREKERELVD--CQRELEKLNKERRLLNQEKTELLVEQGRLQLQADRHQEHIRARDSLIQSLATRLe 378

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  847 LEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQtieekdQQVTEISFSMTEKMVQLNEEKFSLGVE 926
Cdd:TIGR00606  379 LDGFERGPFSERQIKNFHTLVIERQEDEAKTAAQLCADLQSKERLKQ------EQADEIRDEKKGLGRTIELKKEILEKK 452

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  927 IKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQ--NYDEMSPAGQISKEELQHEFDLLKKENEQRKRKLQAALINR-KE 1003
Cdd:TIGR00606  453 QEELKFVIKELQQLEGSSDRILELDQELRKAERElsKAEKNSLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHhTT 532

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1004 LLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIY------LKQTISEKEVELQHIRK 1077
Cdd:TIGR00606  533 TRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLLGYFPNKKQLEDWLHSKSKEINQTrdrlakLNKELASLEQNKNHINN 612

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1078 DLEEKLAAEEQFQALVKQMNQTlQDKTNQIDLLQAEIsENQAIIQKLITSNTDASDGDSVALVKETVVISPPC------T 1151
Cdd:TIGR00606  613 ELESKEEQLSSYEDKLFDVCGS-QDEESDLERLKEEI-EKSSKQRAMLAGATAVYSQFITQLTDENQSCCPVCqrvfqtE 690

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1152 GSSEHWKPELEEKILALEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQ 1231
Cdd:TIGR00606  691 AELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQ 770

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1232 LRQLqiqvrESIDGKLPSTdqqESCSSTPGLEEPLFKATEQHHTQpvlesnlcpdWPSHSEDASALQGGTSVAQIKAQLK 1311
Cdd:TIGR00606  771 ETLL-----GTIMPEEESA---KVCLTDVTIMERFQMELKDVERK----------IAQQAAKLQGSDLDRTVQQVNQEKQ 832

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1312 EIEAEKVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLEHLRE-LQ 1390
Cdd:TIGR00606  833 EKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEqDS 912

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1391 PKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTE----IIEQEDLIKALHTQLEMQAKEHDERIKQLQVELCEMKQK 1466
Cdd:TIGR00606  913 PLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKvkniHGYMKDIENKIQDGKDDYLKQKETELNTVNAQLEECEKH 992

                          810
                   ....*....|...
gi 1034632655 1467 PEEIGEESRAKQQ 1479
Cdd:TIGR00606  993 QEKINEDMRLMRQ 1005
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
275-532 4.49e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 42.70  E-value: 4.49e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  275 DLLQQELTAAEQRNQILSQQLQQMEAEHNTLRNTVETEREESKILLEKMELEVAERKLSfhnlqeemhHLLEQFEQAGQA 354
Cdd:COG3206    164 QNLELRREEARKALEFLEEQLPELRKELEEAEAALEEFRQKNGLVDLSEEAKLLLQQLS---------ELESQLAEARAE 234

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  355 QAELESRYSALEQKHKAEMEEKTSHILS--LQKTGQELQSAcDALKDQNSKLLQDKNEQAVQSAQTIQQLEDQLQQKSKE 432
Cdd:COG3206    235 LAEAEARLAALRAQLGSGPDALPELLQSpvIQQLRAQLAEL-EAELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQR 313

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  433 ISQFLnrlplqqhetasqtsfpdvynEGTQAVTEENIASLQKRVVELENEKGALLLSSIELEELKAENEklSSQITLLEA 512
Cdd:COG3206    314 ILASL---------------------EAELEALQAREASLQAQLAQLEARLAELPELEAELRRLEREVE--VARELYESL 370

                          250       260
                   ....*....|....*....|....
gi 1034632655  513 QNRTGEAD----REVSEISIVDIA 532
Cdd:COG3206    371 LQRLEEARlaeaLTVGNVRVIDPA 394
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1294-1487 4.52e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.98  E-value: 4.52e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1294 ASALQGGTSVAQIKAQLKEIEAEKVELELKVSSTTSELTKKSEEVFQLQEQINKQGLeieslktvsheaevhaeslqQKL 1373
Cdd:COG4913    281 LRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGG--------------------DRL 340

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1374 ESSQLQIAGLE-HLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDER 1452
Cdd:COG4913    341 EQLEREIERLErELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRE 420

                          170       180       190
                   ....*....|....*....|....*....|....*.
gi 1034632655 1453 IKQLQVELCEMKQKPEEIGEES-RAKQQIQRKLQAA 1487
Cdd:COG4913    421 LRELEAEIASLERRKSNIPARLlALRDALAEALGLD 456
PTZ00121 PTZ00121
MAEBL; Provisional
 1970-2509 4.54e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 43.21  E-value: 4.54e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1970 EKQQLVKEKTKVESEIRKEylEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQT 2049
Cdd:PTZ00121  1221 EDAKKAEAVKKAEEAKKDA--EEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKA 1298

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2050 ESQKDLEITK----------ENLAQAVEHRKKAQA--ELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQ 2117
Cdd:PTZ00121  1299 EEKKKADEAKkkaeeakkadEAKKKAEEAKKKADAakKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKK 1378

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2118 KDEDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEiqvTLNKKDKEVQQLQEnLDSTVTQLAAFTKSMSSLQ 2197
Cdd:PTZ00121  1379 KADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKAD---EAKKKAEEKKKADE-AKKKAEEAKKADEAKKKAE 1454

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2198 DDRDRVIDEAKKWERKFSDAIQSKEEEIRLKEDncsvLKDQLRQMSIHMEELKiniSRLEHDKQIWESKAQTEVQLQQKV 2277
Cdd:PTZ00121  1455 EAKKAEEAKKKAEEAKKADEAKKKAEEAKKADE----AKKKAEEAKKKADEAK---KAAEAKKKADEAKKAEEAKKADEA 1527

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2278 CDTLQGENKELLSQLEETRhlyhsSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQ 2357
Cdd:PTZ00121  1528 KKAEEAKKADEAKKAEEKK-----KADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYE 1602

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2358 LETDLQASReltSRLHEEINMKEQKIisllsGKEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKT 2437
Cdd:PTZ00121  1603 EEKKMKAEE---AKKAEEAKIKAEEL-----KKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDK 1674

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1034632655 2438 NQLMETLKT--IKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSIILEKDQLIQEAAAENNKLKE 2509
Cdd:PTZ00121  1675 KKAEEAKKAeeDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEE 1748
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
2583-2993 4.96e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 42.45  E-value: 4.96e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2583 EDLRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTALQeegtlglyhaqlkvKEEEVHRLSALFSSSQKRIAELEEELv 2662
Cdd:COG4717     84 EEKEEEYAELQEELEELEEELEELEAELEELREELEKLE--------------KLLQLLPLYQELEALEAELAELPERL- 148

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2663 cvqkeaakkvgeieDKLKKELKHLHHdagiMRNETETAEERVAELARDLVEMEQKLLMVTKEnkgltaQIQSFGRSMSSL 2742
Cdd:COG4717    149 --------------EELEERLEELRE----LEEELEELEAELAELQEELEELLEQLSLATEE------ELQDLAEELEEL 204

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2743 QNSRDHANEELDELKRKYDASLKELAQLKEQGLLNRERDALLSETAFSMNSTEENSLSHLEKLNQQLLSKDEQLLHLSSQ 2822
Cdd:COG4717    205 QQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLG 284

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2823 LEDSYNQVQSFSKAMASLQNERDHLWNELEKFRKSE--EGKQRSAAQPSTSPAEVQSLKKAMSSLQNDRDRLLKELKNLQ 2900
Cdd:COG4717    285 LLALLFLLLAREKASLGKEAEELQALPALEELEEEEleELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQ 364

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2901 QQYLQINQE----------ITELHPLKAQLQEYQDKTKAFQIMQEELRQENLSWQHELHQLRMEKSSWEIHERRMKEQYL 2970
Cdd:COG4717    365 LEELEQEIAallaeagvedEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEELEELEEELEEL 444

                          410       420
                   ....*....|....*....|....
gi 1034632655 2971 MA-ISDKDQQLSHLQNLIRELRSS 2993
Cdd:COG4717    445 EEeLEELREELAELEAELEQLEED 468
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1302-1502 5.06e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 42.70  E-value: 5.06e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1302 SVAQIKAQLKEIEAEKVELELKVSS--TTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQ 1379
Cdd:COG3206    176 ALEFLEEQLPELRKELEEAEAALEEfrQKNGLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDA 255

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1380 IAGLEHLRELQPKLDELQKLISKKEEdvsyLSGQLSEKEAALTKIQTEIIEQEDLIKA----LHTQLEMQAKEHDERIKQ 1455
Cdd:COG3206    256 LPELLQSPVIQQLRAQLAELEAELAE----LSARYTPNHPDVIALRAQIAALRAQLQQeaqrILASLEAELEALQAREAS 331

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1034632655 1456 LQVELCEMKQKPEEIGEESRAKQQIQRKLQAA------LISRKEALKENKSLQ 1502
Cdd:COG3206    332 LQAQLAQLEARLAELPELEAELRRLEREVEVArelyesLLQRLEEARLAEALT 384
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 1450-1702 5.67e-03

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 42.22  E-value: 5.67e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1450 DERIKQLQ----VELCEMKQkpEEIGEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGT-----IERLTKSLA 1520
Cdd:PRK05771    19 DEVLEALHelgvVHIEDLKE--ELSNERLRKLRSLLTKLSEALDKLRSYLPKLNPLREEKKKVSVKsleelIKDVEEELE 96

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1521 DVESQVSAQNKEkdtvlgrLALLQEERDKLITEMDR-SLLENQSLS----SSCESLKLALEGLTEDKEKLVKEIESLKSS 1595
Cdd:PRK05771    97 KIEKEIKELEEE-------ISELENEIKELEQEIERlEPWGNFDLDlsllLGFKYVSVFVGTVPEDKLEELKLESDVENV 169

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1596 KIAESTEwqEK-------HKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELygklrstEANKKETEKQLqeaeq 1668
Cdd:PRK05771   170 EYISTDK--GYvyvvvvvLKELSDEVEEELKKLGFERLELEEEGTPSELIREIKEEL-------EEIEKERESLL----- 235

                          250       260       270
                   ....*....|....*....|....*....|....*.
gi 1034632655 1669 emeemkEKMRKFAKSKQQKILELEE--ENDRLRAEV 1702
Cdd:PRK05771   236 ------EELKELAKKYLEELLALYEylEIELERAEA 265
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 152-364 5.73e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.06  E-value: 5.73e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  152 KLQEKEELISTLQAQLTQAQAeQPAQSSTEMEEfvmMKQQLQEKEEFISTLQAQLSQTQAEQAAQVvREKDARFETQVRL 231
Cdd:COG4942     42 ELAALKKEEKALLKQLAALER-RIAALARRIRA---LEQELAALEAELAELEKEIAELRAELEAQK-EELAELLRALYRL 116

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  232 HEDELLQLVTQADVETEMQQKLRVLQRKLEEHEEslvgRAQVVDLLQQELTAAEQRNQILSQQLQQMEAEHNTLRNTVET 311
Cdd:COG4942    117 GRQPPLALLLSPEDFLDAVRRLQYLKYLAPARRE----QAEELRADLAELAALRAELEAERAELEALLAELEEERAALEA 192

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1034632655  312 EREESKILLEKMELEVAERKLSFHNLQEEMHHLLEQFEQAGQAQAELESRYSA 364
Cdd:COG4942    193 LKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
2514-2716 5.74e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 42.31  E-value: 5.74e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2514 LRSHMDDLNSENAKLDAELIQYREDLNQvitikdsqqkqlLEVQLQQNKElENKYAKLEEKLKESEEANEDLRRSFNALQ 2593
Cdd:COG3206    166 LELRREEARKALEFLEEQLPELRKELEE------------AEAALEEFRQ-KNGLVDLSEEAKLLLQQLSELESQLAEAR 232

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2594 EEKQDLSKEIESLKVSISQLTRQVTALQEEGTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELVCVQKEAAKKVG 2673
Cdd:COG3206    233 AELAEAEARLAALRAQLGSGPDALPELLQSPVIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQ 312

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|...
gi 1034632655 2674 EIEDKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQ 2716
Cdd:COG3206    313 RILASLEAELEALQAREASLQAQLAQLEARLAELPELEAELRR 355
46 PHA02562
endonuclease subunit; Provisional
 2537-2773 6.00e-03

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 42.31  E-value: 6.00e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2537 EDL--NQVITIKDSQQKQLLEVQLQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQD----LSKEIESLKVSI 2610
Cdd:PHA02562   157 EDLldISVLSEMDKLNKDKIRELNQQIQTLDMKIDHIQQQIKTYNKNIEEQRKKNGENIARKQNkydeLVEEAKTIKAEI 236

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2611 SQLTRQVTALQEEGtlGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELVC------------VQKEAAKKVGEIEDK 2678
Cdd:PHA02562   237 EELTDELLNLVMDI--EDPSAALNKLNTAAAKIKSKIEQFQKVIKMYEKGGVCptctqqisegpdRITKIKDKLKELQHS 314

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2679 LKKELKHLHHDAGIMrNETETAEERVAELARDLVEMEQKLLMVTKENKGLTAQIQsfgrsmsSLQNSRDHANEELDELKR 2758
Cdd:PHA02562   315 LEKLDTAIDELEEIM-DEFNEQSKKLLELKNKISTNKQSLITLVDKAKKVKAAIE-------ELQAEFVDNAEELAKLQD 386

                          250
                   ....*....|....*
gi 1034632655 2759 KYDASLKELAQLKEQ 2773
Cdd:PHA02562   387 ELDKIVKTKSELVKE 401
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 2219-2979 6.28e-03

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 42.34  E-value: 6.28e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2219 QSKEEEIRLKEDNCSVLKDQLRQMsihmEELKINISRLEHDKQIWESkaqTEVQLQQKVCDTLQGENKELLSQLEETRHL 2298
Cdd:TIGR00606  234 ESSREIVKSYENELDPLKNRLKEI----EHNLSKIMKLDNEIKALKS---RKKQMEKDNSELELKMEKVFQGTDEQLNDL 306

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2299 YHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEgiIRQQEADIQNSKFSYEQLETDLQAsreLTSRLHEEINM 2378
Cdd:TIGR00606  307 YHNHQRTVREKERELVDCQRELEKLNKERRLLNQEKTELL--VEQGRLQLQADRHQEHIRARDSLI---QSLATRLELDG 381

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2379 KEQKIISllsgkEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQL 2458
Cdd:TIGR00606  382 FERGPFS-----ERQIKNFHTLVIERQEDEAKTAAQLCADLQSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEEL 456

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2459 DSFVKSMSSLQNDRDRIVGDYQQL--EERHLSIiLEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAE----- 2531
Cdd:TIGR00606  457 KFVIKELQQLEGSSDRILELDQELrkAERELSK-AEKNSLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHtttrt 535

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2532 ----LIQYREDLNQVITIKDSQQKQLLEVQL---QQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSKEIE 2604
Cdd:TIGR00606  536 qmemLTKDKMDKDEQIRKIKSRHSDELTSLLgyfPNKKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELE 615

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2605 SLKVSISQLTRQV----TALQEEGTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELVCVQKeAAKKVGEIEDKLK 2680
Cdd:TIGR00606  616 SKEEQLSSYEDKLfdvcGSQDEESDLERLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSCCP-VCQRVFQTEAELQ 694

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2681 KELKHLHHDAGIMRNETETAEERVAELARD------LVEMEQKLL-MVTKENKGLTAQIQSFGRSMSSLQNSRDHANEEL 2753
Cdd:TIGR00606  695 EFISDLQSKLRLAPDKLKSTESELKKKEKRrdemlgLAPGRQSIIdLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLL 774

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2754 D------ELKRKYDASLKELAQLKEQGLLNRERDALLSETAFSMNSTEEnslshLEKLNQQLLSKDEQLLHLSSQLEDSY 2827
Cdd:TIGR00606  775 GtimpeeESAKVCLTDVTIMERFQMELKDVERKIAQQAAKLQGSDLDRT-----VQQVNQEKQEKQHELDTVVSKIELNR 849

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2828 NQVQSFSKAMASLQNERDHLWNELEKFRKSEEGKQRSAAQPSTSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQ-I 2906
Cdd:TIGR00606  850 KLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEElI 929

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2907 NQEITELHPLKAQLQEYQDKTKA--------FQIMQEELRQENLSWQHELHQLRMEKSSWEIHERRMKEQYLMAISDKDQ 2978
Cdd:TIGR00606  930 SSKETSNKKAQDKVNDIKEKVKNihgymkdiENKIQDGKDDYLKQKETELNTVNAQLEECEKHQEKINEDMRLMRQDIDT 1009


                   .
gi 1034632655 2979 Q 2979
Cdd:TIGR00606 1010 Q 1010
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1057-1236 6.52e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 42.31  E-value: 6.52e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1057 IEIYLKQTISEK-----------EVELQHIRKDLEEKLAAEEQFQA---------LVKQMNQTLQDKTNQIDLLQAEISE 1116
Cdd:COG3206    158 AEAYLEQNLELRreearkaleflEEQLPELRKELEEAEAALEEFRQknglvdlseEAKLLLQQLSELESQLAEARAELAE 237

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1117 NQAIIQKLitSNTDASDGDSVALVKETVVISppctgssehwkpELEEKILALEKEKEQ--------------LQKKLQEA 1182
Cdd:COG3206    238 AEARLAAL--RAQLGSGPDALPELLQSPVIQ------------QLRAQLAELEAELAElsarytpnhpdviaLRAQIAAL 303

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1034632655 1183 LTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQ 1236
Cdd:COG3206    304 RAQLQQEAQRILASLEAELEALQAREASLQAQLAQLEARLAELPELEAELRRLE 357
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 830-1044 6.53e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 41.74  E-value: 6.53e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  830 TLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSM 909
Cdd:COG3883     16 PQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARAL 95

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  910 TEKMVQLNEEKFSLGVE-IKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNydemspagQISKEELQHEFDLLKKENE 988
Cdd:COG3883     96 YRSGGSVSYLDVLLGSEsFSDFLDRLSALSKIADADADLLEELKADKAELEAK--------KAELEAKLAELEALKAELE 167

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1034632655  989 QRKRKLQAALINRKELLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKENKE 1044
Cdd:COG3883    168 AAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAA 223
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
810-1213 6.76e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 42.36  E-value: 6.76e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  810 KIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELS--QALSQKELEITKMDQLLLEKKRD 887
Cdd:PRK03918   232 ELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKelKEKAEEYIKLSEFYEEYLDELRE 311

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  888 VETLQQTIEEKDQQVTEisfsmteKMVQLNEEKfslgVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEMSP 967
Cdd:PRK03918   312 IEKRLSRLEEEINGIEE-------RIKELEEKE----ERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKR 380

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  968 AGQISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELANLKdESKKEIPLSETERGEVEEDKENKEYse 1047
Cdd:PRK03918   381 LTGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELK-KAKGKCPVCGRELTEEHRKELLEEY-- 457

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1048 kcvTSKCQEIEIYLKqTISEKEVELQHIRKDLEEKLAAEEQFQALVKQMNQ--TLQDKTNQIDL--LQAEISENQAIIQK 1123
Cdd:PRK03918   458 ---TAELKRIEKELK-EIEEKERKLRKELRELEKVLKKESELIKLKELAEQlkELEEKLKKYNLeeLEKKAEEYEKLKEK 533

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1124 LITSntdasDGDSVALVKETvvisppctgssehwkpeleEKILALEKEKEQLQKKLQEALTSRKAILKKAQEK----ERH 1199
Cdd:PRK03918   534 LIKL-----KGEIKSLKKEL-------------------EKLEELKKKLAELEKKLDELEEELAELLKELEELgfesVEE 589

                          410
                   ....*....|....
gi 1034632655 1200 LREELKQQKDDYNR 1213
Cdd:PRK03918   590 LEERLKELEPFYNE 603
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 693-1407 6.89e-03

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 42.35  E-value: 6.89e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  693 LELELNFHKAQEIYEKnLDEKAKEISNLNQLIEEFKKNADNNSSAFTA----LSEERDQLLSQVKElSMVTELRAQVKQL 768
Cdd:TIGR01612 1005 LKANLGKNKENMLYHQ-FDEKEKATNDIEQKIEDANKNIPNIEIAIHTsiynIIDEIEKEIGKNIE-LLNKEILEEAEIN 1082

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  769 EMNLAE-AERQRRLDYESQTAHDNL-LTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEV 846
Cdd:TIGR01612 1083 ITNFNEiKEKLKHYNFDDFGKEENIkYADEINKIKDDIKNLDQKIDHHIKALEEIKKKSENYIDEIKAQINDLEDVADKA 1162

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  847 LEGaERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRdVETLQQTIEEkdqqVTEISFSMTEKM-----VQLNEEKF 921
Cdd:TIGR01612 1163 ISN-DDPEEIEKKIENIVTKIDKKKNIYDEIKKLLNEIAE-IEKDKTSLEE----VKGINLSYGKNLgklflEKIDEEKK 1236

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  922 SLGVEIKTLKEQLNLLsraEEAKKEQVEEDNEVSSGLKQNyDEMSPAgQISKEELQHEFDLLKKENEQRKRKLQAALinr 1001
Cdd:TIGR01612 1237 KSEHMIKAMEAYIEDL---DEIKEKSPEIENEMGIEMDIK-AEMETF-NISHDDDKDHHIISKKHDENISDIREKSL--- 1308

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1002 kELLQRVSRlEEELANLKDESKKEIplsetergeVEEDKENkeysekcvtskcQEIEIYLKQTISEKEV-ELQHIRKDLE 1080
Cdd:TIGR01612 1309 -KIIEDFSE-ESDINDIKKELQKNL---------LDAQKHN------------SDINLYLNEIANIYNIlKLNKIKKIID 1365

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1081 EKlaaeEQFQALVKQMNQTLQDKTNQIDLLQAEISENQAI--IQKLITSNTDASDGDSV---ALVKETVVISPPcTGSSE 1155
Cdd:TIGR01612 1366 EV----KEYTKEIEENNKNIKDELDKSEKLIKKIKDDINLeeCKSKIESTLDDKDIDECikkIKELKNHILSEE-SNIDT 1440

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1156 HWK--PELEEKILALEKEKEQLQKKLQEALTSRKailKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLR 1233
Cdd:TIGR01612 1441 YFKnaDENNENVLLLFKNIEMADNKSQHILKIKK---DNATNDHDFNINELKEHIDKSKGCKDEADKNAKAIEKNKELFE 1517

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1234 QLQIQVRESIDgKLPSTDQQESCSSTPGLEEPLFKATEQHHTQPVLES-------NLCPDWPSHSEDASALQGGTSVAQI 1306
Cdd:TIGR01612 1518 QYKKDVTELLN-KYSALAIKNKFAKTKKDSEIIIKEIKDAHKKFILEAekseqkiKEIKKEKFRIEDDAAKNDKSNKAAI 1596

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1307 KAQLKEIEAEKVELELkvssttSELTKKSEEVFQLQEQINKQ--GLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLE 1384
Cdd:TIGR01612 1597 DIQLSLENFENKFLKI------SDIKKKINDCLKETESIEKKisSFSIDSQDTELKENGDNLNSLQEFLESLKDQKKNIE 1670

                          730       740
                   ....*....|....*....|...
gi 1034632655 1385 hlrELQPKLDELQKLISKKEEDV 1407
Cdd:TIGR01612 1671 ---DKKKELDELDSEIEKIEIDV 1690
alph_xenorhab_A NF033928
alpha-xenorhabdolysin family binary toxin subunit A; Alpha-xenorhabdolysin was the founding ...
 2036-2205 7.05e-03

alpha-xenorhabdolysin family binary toxin subunit A; Alpha-xenorhabdolysin was the founding member of a family of alpha-helical pore-forming binary toxins. YaxAB from Yersinia enterocolitica has been studied structurally. This HMM represents subunit A proteins such as XaxA and YaxA, capable of binding to the membrane even in the absence of the B subunit. This family is related to the Bacillus haemolytic enterotoxin family (see PF05791.9), although thresholds for this HMM are set to exclude that family.


Pssm-ID: 468250 [Multi-domain]  Cd Length: 340  Bit Score: 41.52  E-value: 7.05e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2036 ALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFkvlLDDTQSEAARVLADNLKLKKELQSNK----ESV 2111
Cdd:NF033928    88 PIIDLINEMPIIKRGDLTEEELSELPPIPLSSDDKEIVKELKEI---LEDLKNDIKDYQQKADDVKKELDDFEndlrEEL 164

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2112 KSQMKQKDEDLERRLEQAEEKHLKEK-KNMQEKLDALRREKVHLEETIG----------------------EIQVTLNKK 2168
Cdd:NF033928   165 LPQLKLKKKLYDDNLGSDSIEELREKiDQLEKEIEQLNKEYDDYVKLSFtglaggpiglaitggifgskaeKIRKEKNAL 244

                          170       180       190
                   ....*....|....*....|....*....|....*..
gi 1034632655 2169 DKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVID 2205
Cdd:NF033928   245 IQEIDELQEQLKKKNALLGSLERLQTSLDDILTRMED 281
46 PHA02562
endonuclease subunit; Provisional
 2430-2675 7.56e-03

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 41.92  E-value: 7.56e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2430 NKKAVDKTNQLMETLkTIKKENIQQkaQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSIILEKDQLIQEAAAENNKLKE 2509
Cdd:PHA02562   172 NKDKIRELNQQIQTL-DMKIDHIQQ--QIKTYNKNIEEQRKKNGENIARKQNKYDELVEEAKTIKAEIEELTDELLNLVM 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2510 EIRGLRSHMDDLNSENAKLDAELIQYREDlnqvitIKDSQQKQLLEVQLQQNKELENKYAKLEEKLKESEEANEDLRRSF 2589
Cdd:PHA02562   249 DIEDPSAALNKLNTAAAKIKSKIEQFQKV------IKMYEKGGVCPTCTQQISEGPDRITKIKDKLKELQHSLEKLDTAI 322

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2590 NALQE---EKQDLSKEIESLKVSISQLTRQVTAlqeegtlglYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELVCVQK 2666
Cdd:PHA02562   323 DELEEimdEFNEQSKKLLELKNKISTNKQSLIT---------LVDKAKKVKAAIEELQAEFVDNAEELAKLQDELDKIVK 393


                   ....*....
gi 1034632655 2667 EAAKKVGEI 2675
Cdd:PHA02562   394 TKSELVKEK 402
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1839-1992 8.09e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 40.68  E-value: 8.09e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1839 QQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKE------ 1912
Cdd:COG1579     17 SELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNNKEyealqk 96

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1913 ---TAEEEKDDLEERLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEY 1989
Cdd:COG1579     97 eieSLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREELAAKIPPEL 176


                   ...
gi 1034632655 1990 LEK 1992
Cdd:COG1579    177 LAL 179
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 1846-2382 8.12e-03

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 42.08  E-value: 8.12e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1846 ERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAEEEKDDLEERL 1925
Cdd:pfam01576    5 EEMQAKEEELQKVKERQQKAESELKELEKKHQQLCEEKNALQEQLQAETELCAEAEEMRARLAARKQELEEILHELESRL 84

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 1926 MNQLAELNGsignycqdvtdAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSH 2005
Cdd:pfam01576   85 EEEEERSQQ-----------LQNEKKKMQQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKLEEDILLLEDQNSKLSKE 153

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2006 AKELQEL-------LKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELAS 2078
Cdd:pfam01576  154 RKLLEERiseftsnLAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKGRQELEKAKRKLEGESTDLQEQIAELQAQIAE 233

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2079 FKVLLDDTQSEAARVLA---DNLKLKKELQSNKESVKSQMKQKDEDLERRlEQAEEKHLKEKKNMQEKLDALRREKVHLE 2155
Cdd:pfam01576  234 LRAQLAKKEEELQAALArleEETAQKNNALKKIRELEAQISELQEDLESE-RAARNKAEKQRRDLGEELEALKTELEDTL 312

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2156 ETIGEIQVTLNKKDKEVQQLQENLDSTV----TQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEE-------E 2224
Cdd:pfam01576  313 DTTAAQQELRSKREQEVTELKKALEEETrsheAQLQEMRQKHTQALEELTEQLEQAKRNKANLEKAKQALESenaelqaE 392

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2225 IRLKEDNCSVLKDQLRQMSIHMEELKINISRLEHDKQIWE---SKAQTEVQ-------LQQKVCDTLQGENKELLSQLEE 2294
Cdd:pfam01576  393 LRTLQQAKQDSEHKRKKLEGQLQELQARLSESERQRAELAeklSKLQSELEsvssllnEAEGKNIKLSKDVSSLESQLQD 472

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2295 TRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHE 2374
Cdd:pfam01576  473 TQELLQEETRQKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEALEEGKKRLQR 552


                   ....*...
gi 1034632655 2375 EINMKEQK 2382
Cdd:pfam01576  553 ELEALTQQ 560
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 169-333 8.81e-03

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 41.86  E-value: 8.81e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  169 QAQAEQPAQSSTEMEEFVMMKQQLQEKEEfistLQAQLSQTQAEQ--AAQVVREKDARFETQVrlhEDELLQLVTQADVE 246
Cdd:COG3096    508 QALAQRLQQLRAQLAELEQRLRQQQNAER----LLEEFCQRIGQQldAAEELEELLAELEAQL---EELEEQAAEAVEQR 580

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  247 TEMQQKLRVLQRKLEEheesLVGRAQVVDLLQQELTA-AEQRNQILSQQLQQMEAEHNTLRNTVETEREESKILLEKMEL 325
Cdd:COG3096    581 SELRQQLEQLRARIKE----LAARAPAWLAAQDALERlREQSGEALADSQEVTAAMQQLLEREREATVERDELAARKQAL 656


                   ....*...
gi 1034632655  326 EVAERKLS 333
Cdd:COG3096    657 ESQIERLS 664
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
2470-2756 9.18e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 41.82  E-value: 9.18e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2470 NDRDRIVGDY-------QQLEErhlsiileKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLdAELIQYREDLNQV 2542
Cdd:COG4913    593 DDRRRIRSRYvlgfdnrAKLAA--------LEAELAELEEELAEAEERLEALEAELDALQERREAL-QRLAEYSWDEIDV 663

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2543 itikDSQQKQL--LEVQLQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTAL 2620
Cdd:COG4913    664 ----ASAEREIaeLEAELERLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAA 739

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655 2621 QEEGTLGLyHAQLkvkeeEVHRLSALFSSSQKRIAE-LEEELVCVQKEAAKKVGEIEDKLKKELKHLHHDAGIMRNETET 2699
Cdd:COG4913    740 EDLARLEL-RALL-----EERFAAALGDAVERELREnLEERIDALRARLNRAEEELERAMRAFNREWPAETADLDADLES 813

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1034632655 2700 AEERVAELAR----DLVEMEQKLLMVTKENkgltaQIQSFGRSMSSLQNSRDHANEELDEL 2756
Cdd:COG4913    814 LPEYLALLDRleedGLPEYEERFKELLNEN-----SIEFVADLLSKLRRAIREIKERIDPL 869
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
810-1000 9.82e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 41.82  E-value: 9.82e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  810 KIEVLQNELDDVQLQFSEQSTLIRSLQSQLQN--KESEVLEGAERVRHISSKVEELSQALSQKELEITKmdqlLLEKKRD 887
Cdd:COG4913    611 KLAALEAELAELEEELAEAEERLEALEAELDAlqERREALQRLAEYSWDEIDVASAEREIAELEAELER----LDASSDD 686

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632655  888 VETLQQTIEEKDQQVTEisfsmtekmvqLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEE-DNEVSSGLKQNYDEMS 966
Cdd:COG4913    687 LAALEEQLEELEAELEE-----------LEEELDELKGEIGRLEKELEQAEEELDELQDRLEAaEDLARLELRALLEERF 755

                          170       180       190
                   ....*....|....*....|....*....|....*.
gi 1034632655  967 PAGQISK--EELQHEFDLLKKENEQRKRKLQAALIN 1000
Cdd:COG4913    756 AAALGDAveRELRENLEERIDALRARLNRAEEELER 791
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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