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Conserved domains on  [gi|1034555427|ref|XP_016855764|]
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glutamate-rich protein 3 isoform X1 [Homo sapiens]

Protein Classification

UBX domain-containing protein; FRMD7 family protein( domain architecture ID 13866763)

UBX domain-containing protein similar to Schizosaccharomyces pombe protein C17C9.11c| FRMD7 family protein similar to Homo sapiens FERM domain-containing protein 7 (FRMD7) that plays a role in neurite development, and N-terminal region of Homo sapiens FERM, ARHGEF and pleckstrin domain-containing protein 1/2 that functions as guanine nucleotide exchange factor for RAC1

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
DUF4590 pfam15257
Domain of unknown function (DUF4590); This family of proteins remains to be characterized and ...
297-409 5.69e-73

Domain of unknown function (DUF4590); This family of proteins remains to be characterized and is a domain of unknown function. This domain family is found in eukaryotes, and is approximately 120 amino acids in length. There are two conserved sequence motifs: CCE and PCY. In humans, the gene encoding this protein lies in the position, chromosome 1 open reading frame 173.


:

Pssm-ID: 464597  Cd Length: 114  Bit Score: 238.04  E-value: 5.69e-73
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034555427  297 HLSSDNPDFRDEIKVYQQHCGGENLCVYKGKLLEKETFQFISKRHHGFPFSLTFFLNGMQVNRLSSCCEYKHRKGSRLGG 376
Cdd:pfam15257    1 HLSHDQFDYRDEIKVYQQHCGGENLCVFKGKLLEGETFQFISRRHRGFPFSLTFYLNGLQVDRLSSCCEYKHRKGSRLGG 80
                           90       100       110
                   ....*....|....*....|....*....|...
gi 1034555427  377 KRGYFGFVCVERSSPCYKCIIAMGLDKKPSLPK 409
Cdd:pfam15257   81 KSGHFGFLSVEGASPCYKCIIAMGLDKKPSPPP 113
PTZ00121 super family cl31754
MAEBL; Provisional
411-1119 1.56e-06

MAEBL; Provisional


The actual alignment was detected with superfamily member PTZ00121:

Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 53.22  E-value: 1.56e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034555427  411 RKEKSTEKGEELKKAEGKVRKEREYVIPKRNEIKENKTSVSAKfSAQEIKTGLKEVVTAVEEMTSKG--KPGQEVLEDDQ 488
Cdd:PTZ00121  1188 RKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVK-KAEEAKKDAEEAKKAEEERNNEEirKFEEARMAHFA 1266
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034555427  489 ENTLKYEYEEDFEVDEEKQGEksnEEGQADVQMNGIPQSPLDDKKDNLDPEKESETSSQKAPDARDNVKDendgcSESEL 568
Cdd:PTZ00121  1267 RRQAAIKAEEARKADELKKAE---EKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADA-----AKKKA 1338
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034555427  569 EEDKQDMKTASSTSSRSHPYSSDSEDESAVGDREAHTDSSTDESARRSSSQELSENDKPRKSHLPIEESLEIEIEDQEIT 648
Cdd:PTZ00121  1339 EEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKK 1418
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034555427  649 KADVETKPMPIDESFENVLKEGTEKGTQEIAEGLSEKSGKHVSAEEKEKDKSKLWEESTAQVKDKKAglpglEEGGKDsl 728
Cdd:PTZ00121  1419 KADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKA-----DEAKKK-- 1491
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034555427  729 playvlalgaptmnfmvdetaAINSNKESQQLVQKTYtlEKKEAMEEDEAPQHRDADIVQGKGEAALWGEAGAVHEaplr 808
Cdd:PTZ00121  1492 ---------------------AEEAKKKADEAKKAAE--AKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEE---- 1544
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034555427  809 awKPTAEQPELAEEFTEKREIPPGIERGAEGAAEAEGVRRLGEggsdpigqaaakdavgLSKDEAPEKQALMLTVLETDK 888
Cdd:PTZ00121  1545 --KKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEE----------------AKKAEEARIEEVMKLYEEEKK 1606
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034555427  889 AASEGEQGLEKAVLANEAAALNLEHLHEVAALREAATSEEGEAEggvavsDVGESEEEASIDledtgpMEDTASKREDGS 968
Cdd:PTZ00121  1607 MKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAE------ELKKAEEENKIK------AAEEAKKAEEDK 1674
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034555427  969 EEAilggEEPAKERKEVMRTEtrlspftgeaEASRMQVSEGSPEEGSLAKEAflckEDVEGEEMVTEAEANREDDRKEIl 1048
Cdd:PTZ00121  1675 KKA----EEAKKAEEDEKKAA----------EALKKEAEEAKKAEELKKKEA----EEKKKAEELKKAEEENKIKAEEA- 1735
                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1034555427 1049 pkeldlareRRKAERPKTSLRKTDSEREEVTRANALKDEDAFKEEQKLKAEEGETETEVRAEEETKAPPNE 1119
Cdd:PTZ00121  1736 ---------KKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVD 1797
PTZ00121 super family cl31754
MAEBL; Provisional
946-1412 1.28e-04

MAEBL; Provisional


The actual alignment was detected with superfamily member PTZ00121:

Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 47.06  E-value: 1.28e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034555427  946 EASIDLEDTGPMEDTASKREDGSEEAILGGEEPAKERKEVMRTE-TRLSPFTGEAEASRM-----QVSEGSPEEGSLAKE 1019
Cdd:PTZ00121  1203 EAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEeERNNEEIRKFEEARMahfarRQAAIKAEEARKADE 1282
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034555427 1020 AFLCKEDVEGEEMVTEAEANREDDRKEILPKELDLARERRKAERPKTSLRKTDSEREEVTRANALKDEDAFKEEQKLKAE 1099
Cdd:PTZ00121  1283 LKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAA 1362
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034555427 1100 EGETETEVRAEEETKAPPNEMGSDAENEAPVEASELSDNPGLLGEDSLKETVVPIFEATPGFEKSLENITALRKEGGGER 1179
Cdd:PTZ00121  1363 EEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEE 1442
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034555427 1180 LSEARDTEHKDREELSSRENRALKEGHRQDGEGAL--AAPEAEPAGKVQAPEglipATGQAEELAAKDHDSCAGLEGR-A 1256
Cdd:PTZ00121  1443 AKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKkaEEAKKADEAKKKAEE----AKKKADEAKKAAEAKKKADEAKkA 1518
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034555427 1257 EGQGGVDVVLRTQEAVAEEDPIMAEKFREEAVDEDPEEEEDKECTLETEAMQDRNSEGDGDMEGEGNTQKNEGMGGGRVV 1336
Cdd:PTZ00121  1519 EEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVM 1598
                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1034555427 1337 AVEVLHGGGETAETAAEEREVLAGSETAEEKTIANKASSFSDVAEEETwhQQDELVGKTAAAGKVVVEELARSGEE 1412
Cdd:PTZ00121  1599 KLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEK--KKAEELKKAEEENKIKAAEEAKKAEE 1672
 
Name Accession Description Interval E-value
DUF4590 pfam15257
Domain of unknown function (DUF4590); This family of proteins remains to be characterized and ...
297-409 5.69e-73

Domain of unknown function (DUF4590); This family of proteins remains to be characterized and is a domain of unknown function. This domain family is found in eukaryotes, and is approximately 120 amino acids in length. There are two conserved sequence motifs: CCE and PCY. In humans, the gene encoding this protein lies in the position, chromosome 1 open reading frame 173.


Pssm-ID: 464597  Cd Length: 114  Bit Score: 238.04  E-value: 5.69e-73
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034555427  297 HLSSDNPDFRDEIKVYQQHCGGENLCVYKGKLLEKETFQFISKRHHGFPFSLTFFLNGMQVNRLSSCCEYKHRKGSRLGG 376
Cdd:pfam15257    1 HLSHDQFDYRDEIKVYQQHCGGENLCVFKGKLLEGETFQFISRRHRGFPFSLTFYLNGLQVDRLSSCCEYKHRKGSRLGG 80
                           90       100       110
                   ....*....|....*....|....*....|...
gi 1034555427  377 KRGYFGFVCVERSSPCYKCIIAMGLDKKPSLPK 409
Cdd:pfam15257   81 KSGHFGFLSVEGASPCYKCIIAMGLDKKPSPPP 113
PTZ00121 PTZ00121
MAEBL; Provisional
411-1119 1.56e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 53.22  E-value: 1.56e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034555427  411 RKEKSTEKGEELKKAEGKVRKEREYVIPKRNEIKENKTSVSAKfSAQEIKTGLKEVVTAVEEMTSKG--KPGQEVLEDDQ 488
Cdd:PTZ00121  1188 RKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVK-KAEEAKKDAEEAKKAEEERNNEEirKFEEARMAHFA 1266
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034555427  489 ENTLKYEYEEDFEVDEEKQGEksnEEGQADVQMNGIPQSPLDDKKDNLDPEKESETSSQKAPDARDNVKDendgcSESEL 568
Cdd:PTZ00121  1267 RRQAAIKAEEARKADELKKAE---EKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADA-----AKKKA 1338
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034555427  569 EEDKQDMKTASSTSSRSHPYSSDSEDESAVGDREAHTDSSTDESARRSSSQELSENDKPRKSHLPIEESLEIEIEDQEIT 648
Cdd:PTZ00121  1339 EEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKK 1418
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034555427  649 KADVETKPMPIDESFENVLKEGTEKGTQEIAEGLSEKSGKHVSAEEKEKDKSKLWEESTAQVKDKKAglpglEEGGKDsl 728
Cdd:PTZ00121  1419 KADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKA-----DEAKKK-- 1491
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034555427  729 playvlalgaptmnfmvdetaAINSNKESQQLVQKTYtlEKKEAMEEDEAPQHRDADIVQGKGEAALWGEAGAVHEaplr 808
Cdd:PTZ00121  1492 ---------------------AEEAKKKADEAKKAAE--AKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEE---- 1544
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034555427  809 awKPTAEQPELAEEFTEKREIPPGIERGAEGAAEAEGVRRLGEggsdpigqaaakdavgLSKDEAPEKQALMLTVLETDK 888
Cdd:PTZ00121  1545 --KKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEE----------------AKKAEEARIEEVMKLYEEEKK 1606
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034555427  889 AASEGEQGLEKAVLANEAAALNLEHLHEVAALREAATSEEGEAEggvavsDVGESEEEASIDledtgpMEDTASKREDGS 968
Cdd:PTZ00121  1607 MKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAE------ELKKAEEENKIK------AAEEAKKAEEDK 1674
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034555427  969 EEAilggEEPAKERKEVMRTEtrlspftgeaEASRMQVSEGSPEEGSLAKEAflckEDVEGEEMVTEAEANREDDRKEIl 1048
Cdd:PTZ00121  1675 KKA----EEAKKAEEDEKKAA----------EALKKEAEEAKKAEELKKKEA----EEKKKAEELKKAEEENKIKAEEA- 1735
                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1034555427 1049 pkeldlareRRKAERPKTSLRKTDSEREEVTRANALKDEDAFKEEQKLKAEEGETETEVRAEEETKAPPNE 1119
Cdd:PTZ00121  1736 ---------KKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVD 1797
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
906-1211 4.48e-05

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 48.45  E-value: 4.48e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034555427  906 AAALNLEHLHEVAALREAATSEEGEAEGGVAVSDVGESEEEASIDLEDTGPMEDTASKREDGSEEAILGGEEPAKERKEV 985
Cdd:TIGR00927  622 AKVMALGDLSKGDVAEAEHTGERTGEEGERPTEAEGENGEESGGEAEQEGETETKGENESEGEIPAERKGEQEGEGEIEA 701
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034555427  986 MRTETRLSPFTGEAEASRMQVSEGSPEEGSLAKEAflcKEDVEGEEMVTEAEANREDDrkeilpkeldlarerRKAERPK 1065
Cdd:TIGR00927  702 KEADHKGETEAEEVEHEGETEAEGTEDEGEIETGE---EGEEVEDEGEGEAEGKHEVE---------------TEGDRKE 763
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034555427 1066 TslrktdsEREEVTRANALKDEDafkeEQKLKAEEGETETEVRAEEETKAPPNEMGSDAENEAPVEASELSDNPGLLGED 1145
Cdd:TIGR00927  764 T-------EHEGETEAEGKEDED----EGEIQAGEDGEMKGDEGAEGKVEHEGETEAGEKDEHEGQSETQADDTEVKDET 832
                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1034555427 1146 SLKETVVPIFEATPGFEKSLENitalrkeGGGERLSEARDTEHKDREELSSRENRALKEGHRQDGE 1211
Cdd:TIGR00927  833 GEQELNAENQGEAKQDEKGVDG-------GGGSDGGDSEEEEEEEEEEEEEEEEEEEEEEEEEENE 891
PTZ00121 PTZ00121
MAEBL; Provisional
946-1412 1.28e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 47.06  E-value: 1.28e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034555427  946 EASIDLEDTGPMEDTASKREDGSEEAILGGEEPAKERKEVMRTE-TRLSPFTGEAEASRM-----QVSEGSPEEGSLAKE 1019
Cdd:PTZ00121  1203 EAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEeERNNEEIRKFEEARMahfarRQAAIKAEEARKADE 1282
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034555427 1020 AFLCKEDVEGEEMVTEAEANREDDRKEILPKELDLARERRKAERPKTSLRKTDSEREEVTRANALKDEDAFKEEQKLKAE 1099
Cdd:PTZ00121  1283 LKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAA 1362
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034555427 1100 EGETETEVRAEEETKAPPNEMGSDAENEAPVEASELSDNPGLLGEDSLKETVVPIFEATPGFEKSLENITALRKEGGGER 1179
Cdd:PTZ00121  1363 EEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEE 1442
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034555427 1180 LSEARDTEHKDREELSSRENRALKEGHRQDGEGAL--AAPEAEPAGKVQAPEglipATGQAEELAAKDHDSCAGLEGR-A 1256
Cdd:PTZ00121  1443 AKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKkaEEAKKADEAKKKAEE----AKKKADEAKKAAEAKKKADEAKkA 1518
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034555427 1257 EGQGGVDVVLRTQEAVAEEDPIMAEKFREEAVDEDPEEEEDKECTLETEAMQDRNSEGDGDMEGEGNTQKNEGMGGGRVV 1336
Cdd:PTZ00121  1519 EEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVM 1598
                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1034555427 1337 AVEVLHGGGETAETAAEEREVLAGSETAEEKTIANKASSFSDVAEEETwhQQDELVGKTAAAGKVVVEELARSGEE 1412
Cdd:PTZ00121  1599 KLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEK--KKAEELKKAEEENKIKAAEEAKKAEE 1672
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
1303-1508 1.65e-04

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 46.53  E-value: 1.65e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034555427 1303 ETEAMQDRNSEGDGDMEGEGNTQKNEGMGGGRVVAVEVLHGGGETAETAAEEREVLAGSETAE----------------- 1365
Cdd:TIGR00927  678 ENESEGEIPAERKGEQEGEGEIEAKEADHKGETEAEEVEHEGETEAEGTEDEGEIETGEEGEEvedegegeaegkhevet 757
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034555427 1366 -------EKTIANKASSFSDVAEEETWHQQD-ELVGKTAAAGKVVVEELARSGEEVPAAEEMTVTYTTEAGVGTPGalER 1437
Cdd:TIGR00927  758 egdrketEHEGETEAEGKEDEDEGEIQAGEDgEMKGDEGAEGKVEHEGETEAGEKDEHEGQSETQADDTEVKDETG--EQ 835
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1034555427 1438 KTSGLGQEQEEGSEGQEAATGSGDGrQETGAAEKFRLGLSREGERELSPESLQAMATLPVKPDFTETREKQ 1508
Cdd:TIGR00927  836 ELNAENQGEAKQDEKGVDGGGGSDG-GDSEEEEEEEEEEEEEEEEEEEEEEEEEENEEPLSLEWPETRQKQ 905
 
Name Accession Description Interval E-value
DUF4590 pfam15257
Domain of unknown function (DUF4590); This family of proteins remains to be characterized and ...
297-409 5.69e-73

Domain of unknown function (DUF4590); This family of proteins remains to be characterized and is a domain of unknown function. This domain family is found in eukaryotes, and is approximately 120 amino acids in length. There are two conserved sequence motifs: CCE and PCY. In humans, the gene encoding this protein lies in the position, chromosome 1 open reading frame 173.


Pssm-ID: 464597  Cd Length: 114  Bit Score: 238.04  E-value: 5.69e-73
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034555427  297 HLSSDNPDFRDEIKVYQQHCGGENLCVYKGKLLEKETFQFISKRHHGFPFSLTFFLNGMQVNRLSSCCEYKHRKGSRLGG 376
Cdd:pfam15257    1 HLSHDQFDYRDEIKVYQQHCGGENLCVFKGKLLEGETFQFISRRHRGFPFSLTFYLNGLQVDRLSSCCEYKHRKGSRLGG 80
                           90       100       110
                   ....*....|....*....|....*....|...
gi 1034555427  377 KRGYFGFVCVERSSPCYKCIIAMGLDKKPSLPK 409
Cdd:pfam15257   81 KSGHFGFLSVEGASPCYKCIIAMGLDKKPSPPP 113
PTZ00121 PTZ00121
MAEBL; Provisional
411-1119 1.56e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 53.22  E-value: 1.56e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034555427  411 RKEKSTEKGEELKKAEGKVRKEREYVIPKRNEIKENKTSVSAKfSAQEIKTGLKEVVTAVEEMTSKG--KPGQEVLEDDQ 488
Cdd:PTZ00121  1188 RKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVK-KAEEAKKDAEEAKKAEEERNNEEirKFEEARMAHFA 1266
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034555427  489 ENTLKYEYEEDFEVDEEKQGEksnEEGQADVQMNGIPQSPLDDKKDNLDPEKESETSSQKAPDARDNVKDendgcSESEL 568
Cdd:PTZ00121  1267 RRQAAIKAEEARKADELKKAE---EKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADA-----AKKKA 1338
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034555427  569 EEDKQDMKTASSTSSRSHPYSSDSEDESAVGDREAHTDSSTDESARRSSSQELSENDKPRKSHLPIEESLEIEIEDQEIT 648
Cdd:PTZ00121  1339 EEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKK 1418
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034555427  649 KADVETKPMPIDESFENVLKEGTEKGTQEIAEGLSEKSGKHVSAEEKEKDKSKLWEESTAQVKDKKAglpglEEGGKDsl 728
Cdd:PTZ00121  1419 KADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKA-----DEAKKK-- 1491
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034555427  729 playvlalgaptmnfmvdetaAINSNKESQQLVQKTYtlEKKEAMEEDEAPQHRDADIVQGKGEAALWGEAGAVHEaplr 808
Cdd:PTZ00121  1492 ---------------------AEEAKKKADEAKKAAE--AKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEE---- 1544
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034555427  809 awKPTAEQPELAEEFTEKREIPPGIERGAEGAAEAEGVRRLGEggsdpigqaaakdavgLSKDEAPEKQALMLTVLETDK 888
Cdd:PTZ00121  1545 --KKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEE----------------AKKAEEARIEEVMKLYEEEKK 1606
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034555427  889 AASEGEQGLEKAVLANEAAALNLEHLHEVAALREAATSEEGEAEggvavsDVGESEEEASIDledtgpMEDTASKREDGS 968
Cdd:PTZ00121  1607 MKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAE------ELKKAEEENKIK------AAEEAKKAEEDK 1674
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034555427  969 EEAilggEEPAKERKEVMRTEtrlspftgeaEASRMQVSEGSPEEGSLAKEAflckEDVEGEEMVTEAEANREDDRKEIl 1048
Cdd:PTZ00121  1675 KKA----EEAKKAEEDEKKAA----------EALKKEAEEAKKAEELKKKEA----EEKKKAEELKKAEEENKIKAEEA- 1735
                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1034555427 1049 pkeldlareRRKAERPKTSLRKTDSEREEVTRANALKDEDAFKEEQKLKAEEGETETEVRAEEETKAPPNE 1119
Cdd:PTZ00121  1736 ---------KKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVD 1797
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
906-1211 4.48e-05

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 48.45  E-value: 4.48e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034555427  906 AAALNLEHLHEVAALREAATSEEGEAEGGVAVSDVGESEEEASIDLEDTGPMEDTASKREDGSEEAILGGEEPAKERKEV 985
Cdd:TIGR00927  622 AKVMALGDLSKGDVAEAEHTGERTGEEGERPTEAEGENGEESGGEAEQEGETETKGENESEGEIPAERKGEQEGEGEIEA 701
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034555427  986 MRTETRLSPFTGEAEASRMQVSEGSPEEGSLAKEAflcKEDVEGEEMVTEAEANREDDrkeilpkeldlarerRKAERPK 1065
Cdd:TIGR00927  702 KEADHKGETEAEEVEHEGETEAEGTEDEGEIETGE---EGEEVEDEGEGEAEGKHEVE---------------TEGDRKE 763
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034555427 1066 TslrktdsEREEVTRANALKDEDafkeEQKLKAEEGETETEVRAEEETKAPPNEMGSDAENEAPVEASELSDNPGLLGED 1145
Cdd:TIGR00927  764 T-------EHEGETEAEGKEDED----EGEIQAGEDGEMKGDEGAEGKVEHEGETEAGEKDEHEGQSETQADDTEVKDET 832
                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1034555427 1146 SLKETVVPIFEATPGFEKSLENitalrkeGGGERLSEARDTEHKDREELSSRENRALKEGHRQDGE 1211
Cdd:TIGR00927  833 GEQELNAENQGEAKQDEKGVDG-------GGGSDGGDSEEEEEEEEEEEEEEEEEEEEEEEEEENE 891
PTZ00341 PTZ00341
Ring-infected erythrocyte surface antigen; Provisional
412-697 1.16e-04

Ring-infected erythrocyte surface antigen; Provisional


Pssm-ID: 173534 [Multi-domain]  Cd Length: 1136  Bit Score: 47.09  E-value: 1.16e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034555427  412 KEKSTEKGEELKKAEGKVRKereYVIPKRNEIKenktsvSAKFSAQEIKTGL-KEVVTAVEEMTSKGKPGQEVLEDDQEN 490
Cdd:PTZ00341   875 EKKLKKRAESLKKLANAIEK---YAGGGKKDKK------AKKKDAKDLSGNIaHEINLINKELKNQNENVPEHLKEHAEA 945
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034555427  491 TLKYEYEEDFEVDEEKQGEKSNEEGqadvqmngIPQSPLDDKKDNLDPEKESETSSQKAPDARDNVKDENDGCSESELEE 570
Cdd:PTZ00341   946 NIEEDAEENVEEDAEENVEENVEEN--------VEENVEENVEENVEENVEENVEENVEENVEENIEENVEENVEENIEE 1017
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034555427  571 DKQDMKTASSTSSRSHPYSSDSEDESAVgdreahtdsstDESARRSSSQELSENDKPRKSHLPIEESLEIEIEDQEITKA 650
Cdd:PTZ00341  1018 NVEEYDEENVEEVEENVEEYDEENVEEI-----------EENAEENVEENIEENIEEYDEENVEEIEENIEENIEENVEE 1086
                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*..
gi 1034555427  651 DVETKPMPIDESFENVLKEGTEKGTQEIAEGLSEKSGKHVSAEEKEK 697
Cdd:PTZ00341  1087 NVEENVEEIEENVEENVEENAEENAEENAEENAEEYDDENPEEHNEE 1133
PTZ00121 PTZ00121
MAEBL; Provisional
946-1412 1.28e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 47.06  E-value: 1.28e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034555427  946 EASIDLEDTGPMEDTASKREDGSEEAILGGEEPAKERKEVMRTE-TRLSPFTGEAEASRM-----QVSEGSPEEGSLAKE 1019
Cdd:PTZ00121  1203 EAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEeERNNEEIRKFEEARMahfarRQAAIKAEEARKADE 1282
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034555427 1020 AFLCKEDVEGEEMVTEAEANREDDRKEILPKELDLARERRKAERPKTSLRKTDSEREEVTRANALKDEDAFKEEQKLKAE 1099
Cdd:PTZ00121  1283 LKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAA 1362
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034555427 1100 EGETETEVRAEEETKAPPNEMGSDAENEAPVEASELSDNPGLLGEDSLKETVVPIFEATPGFEKSLENITALRKEGGGER 1179
Cdd:PTZ00121  1363 EEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEE 1442
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034555427 1180 LSEARDTEHKDREELSSRENRALKEGHRQDGEGAL--AAPEAEPAGKVQAPEglipATGQAEELAAKDHDSCAGLEGR-A 1256
Cdd:PTZ00121  1443 AKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKkaEEAKKADEAKKKAEE----AKKKADEAKKAAEAKKKADEAKkA 1518
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034555427 1257 EGQGGVDVVLRTQEAVAEEDPIMAEKFREEAVDEDPEEEEDKECTLETEAMQDRNSEGDGDMEGEGNTQKNEGMGGGRVV 1336
Cdd:PTZ00121  1519 EEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVM 1598
                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1034555427 1337 AVEVLHGGGETAETAAEEREVLAGSETAEEKTIANKASSFSDVAEEETwhQQDELVGKTAAAGKVVVEELARSGEE 1412
Cdd:PTZ00121  1599 KLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEK--KKAEELKKAEEENKIKAAEEAKKAEE 1672
PTZ00121 PTZ00121
MAEBL; Provisional
553-1276 1.35e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 47.06  E-value: 1.35e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034555427  553 RDNVKDENDGCSESELEEDKQDMKTASSTSSRSHPYSSDSEDESAVGDREAHTDSSTDESARRssSQELSENDKPRKSHl 632
Cdd:PTZ00121  1085 EDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARK--AEDAKRVEIARKAE- 1161
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034555427  633 pIEESLEIEIEDQEITKADVETKPMPIDESFEnVLKEGTEKGTQEIAEGLSEKSGKHVSAEEKEKDKSKLWEESTAQVKD 712
Cdd:PTZ00121  1162 -DARKAEEARKAEDAKKAEAARKAEEVRKAEE-LRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDA 1239
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034555427  713 KKAglpglEEGGKDSLPLAYVLALGAPTMNFMVDETAAINSNKESQQLVQKTYtlEKKEAMEEDEAPQHRDADIVQGKGE 792
Cdd:PTZ00121  1240 EEA-----KKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAE--EKKKADEAKKAEEKKKADEAKKKAE 1312
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034555427  793 AALWGEAG--AVHEAPLRA--WKPTAEQPELAEEFTEKREIPPGIERGAEGAAEAEGVRRLGEGGSDpiGQAAAKDAVGL 868
Cdd:PTZ00121  1313 EAKKADEAkkKAEEAKKKAdaAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKK--ADAAKKKAEEK 1390
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034555427  869 SKDEAPEKQAlmltvlETDKAASEGEQGLEKAVLANEAAALNLEHLHEVAALREAAtSEEGEAEGGVAVSDVGESEEEAS 948
Cdd:PTZ00121  1391 KKADEAKKKA------EEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKA-EEAKKADEAKKKAEEAKKAEEAK 1463
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034555427  949 IDLEDTGPMEDTASKREDG--SEEAILGGEEPAKERKEVMRTETRlspfTGEAEASRMQVSEGSPEEGSLAKEAFLCKED 1026
Cdd:PTZ00121  1464 KKAEEAKKADEAKKKAEEAkkADEAKKKAEEAKKKADEAKKAAEA----KKKADEAKKAEEAKKADEAKKAEEAKKADEA 1539
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034555427 1027 VEGEEMVTEAEANREDDRKEilPKELDLARERRKAERPKTSLRKTDSEREEVTRANALKDEDAFKEEQKLKAEEGETETE 1106
Cdd:PTZ00121  1540 KKAEEKKKADELKKAEELKK--AEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEE 1617
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034555427 1107 VRAEEETKAPPNEMGSDAENEAPVEASELSDNPGLLGEDslKETVVPIFEATPGFEKSLENITALRKEGGGERLSEardt 1186
Cdd:PTZ00121  1618 AKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAE--EENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAA---- 1691
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034555427 1187 EHKDREELSSRENRALKEGHRQDGEGALAAPEAEPAGKVQAPEGLIPA---TGQAEELAAKDHDSCAGLEGRAEGQGGVD 1263
Cdd:PTZ00121  1692 EALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAeedKKKAEEAKKDEEEKKKIAHLKKEEEKKAE 1771
                          730
                   ....*....|...
gi 1034555427 1264 VVLRTQEAVAEED 1276
Cdd:PTZ00121  1772 EIRKEKEAVIEEE 1784
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
1303-1508 1.65e-04

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 46.53  E-value: 1.65e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034555427 1303 ETEAMQDRNSEGDGDMEGEGNTQKNEGMGGGRVVAVEVLHGGGETAETAAEEREVLAGSETAE----------------- 1365
Cdd:TIGR00927  678 ENESEGEIPAERKGEQEGEGEIEAKEADHKGETEAEEVEHEGETEAEGTEDEGEIETGEEGEEvedegegeaegkhevet 757
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034555427 1366 -------EKTIANKASSFSDVAEEETWHQQD-ELVGKTAAAGKVVVEELARSGEEVPAAEEMTVTYTTEAGVGTPGalER 1437
Cdd:TIGR00927  758 egdrketEHEGETEAEGKEDEDEGEIQAGEDgEMKGDEGAEGKVEHEGETEAGEKDEHEGQSETQADDTEVKDETG--EQ 835
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1034555427 1438 KTSGLGQEQEEGSEGQEAATGSGDGrQETGAAEKFRLGLSREGERELSPESLQAMATLPVKPDFTETREKQ 1508
Cdd:TIGR00927  836 ELNAENQGEAKQDEKGVDGGGGSDG-GDSEEEEEEEEEEEEEEEEEEEEEEEEEENEEPLSLEWPETRQKQ 905
PTZ00121 PTZ00121
MAEBL; Provisional
404-1076 7.00e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 41.28  E-value: 7.00e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034555427  404 KPSLPKSRKEKSTEKGEELKKAEgKVRKEREYVIPKRNEIKenKTSVSAKFSAQEIKTGLKEVVTAVEEMTSKGKPGQEV 483
Cdd:PTZ00121  1296 KKAEEKKKADEAKKKAEEAKKAD-EAKKKAEEAKKKADAAK--KKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKK 1372
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034555427  484 LEDDQE--NTLKYEYEEDFEVDEEKQGEKSNEEGQADVQMNGIPQSPLDDKKDNLDPEKESETSSQKAPDAR--DNVKDE 559
Cdd:PTZ00121  1373 KEEAKKkaDAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKkaDEAKKK 1452
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034555427  560 NDGCSESE-LEEDKQDMKTASSTSSRSHPYSSDSEDESAVGDREAHTDSSTDESARRSSSQELSENDKPRKShlpieesl 638
Cdd:PTZ00121  1453 AEEAKKAEeAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKA-------- 1524
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034555427  639 eieiedQEITKADVETKPMPIDESfENVLKEGTEKGTQEIAEglseksgkhvsAEEKEKDKSKLWEESTAQVKDKKAG-L 717
Cdd:PTZ00121  1525 ------DEAKKAEEAKKADEAKKA-EEKKKADELKKAEELKK-----------AEEKKKAEEAKKAEEDKNMALRKAEeA 1586
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034555427  718 PGLEEGGKDSLPLAYVLALGAPTMNFMVDETAAINSN--KESQQLVQKTYTLEKKEAMEEDEAPQHRDADivqgkgeaal 795
Cdd:PTZ00121  1587 KKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEelKKAEEEKKKVEQLKKKEAEEKKKAEELKKAE---------- 1656
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034555427  796 wgEAGAVHEAPLRAW----KPTAEQPELAEEftEKREIPPGIERGAEGAAEAEGVRRLGEggsdpigqAAAKDAVGLSKD 871
Cdd:PTZ00121  1657 --EENKIKAAEEAKKaeedKKKAEEAKKAEE--DEKKAAEALKKEAEEAKKAEELKKKEA--------EEKKKAEELKKA 1724
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034555427  872 EAPEKqalmltvLETDKAASEGEQGLEKAvlanEAAALNLEHLHEVAALREaatSEEGEAEGGVAVSDVGESEEEASIDL 951
Cdd:PTZ00121  1725 EEENK-------IKAEEAKKEAEEDKKKA----EEAKKDEEEKKKIAHLKK---EEEKKAEEIRKEKEAVIEEELDEEDE 1790
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034555427  952 EDTGPMEDTASKREDGSEEAILGGEEPA---KERKEVMRTETRLSpftgeAEASRMQVsegspEEGSLAKEAFLCKEDVE 1028
Cdd:PTZ00121  1791 KRRMEVDKKIKDIFDNFANIIEGGKEGNlviNDSKEMEDSAIKEV-----ADSKNMQL-----EEADAFEKHKFNKNNEN 1860
                          650       660       670       680
                   ....*....|....*....|....*....|....*....|....*...
gi 1034555427 1029 GEEMVTEAEANREDDRKEILPKELDLARERRKaerpktsLRKTDSERE 1076
Cdd:PTZ00121  1861 GEDGNKEADFNKEKDLKEDDEEEIEEADEIEK-------IDKDDIERE 1901
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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