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Conserved domains on  [gi|1622953050|ref|XP_014997674|]
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centrosomal protein of 152 kDa isoform X2 [Macaca mulatta]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
220-860 2.58e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 68.93  E-value: 2.58e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  220 FEGLQQQFLG-ANENSAENMQIIQLQVLNKAKERQLENLVEKLNESECQIRYLNHQLVIIKDEKDGLTLSLresQKLFQN 298
Cdd:TIGR02168  346 LEELKEELESlEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRR---ERLQQE 422
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  299 GKEREIQL-EAQIKALETQIQALKVNEEQMIKKSRTTEMALESLKQQLVDLHHSESLQRAREQHESVVMGLTKKYEEQVL 377
Cdd:TIGR02168  423 IEELLKKLeEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLE 502
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  378 SLQKNLDATVTALKEQEDICSRLKDHVKQLERNQEAIKLEKTEIINRLTRSLEESQKQCAHLLQSGSVQEVAQLQFQLQQ 457
Cdd:TIGR02168  503 GFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIK 582
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  458 AQKAHTMSENMNKALQEELTELKDEISLYESAAKL------GIHPSDSEG---ELNIELTESY--VDLGIKKVNWK---- 522
Cdd:TIGR02168  583 GTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKAlsyllgGVLVVDDLDnalELAKKLRPGYriVTLDGDLVRPGgvit 662
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  523 ---KSKVNSIVQQEDPNEELSKD-----EFILKLKAEVQRLLGSNS--------------MKRRLVSQLQNDLKDCHKKI 580
Cdd:TIGR02168  663 ggsAKTNSSILERRREIEELEEKieeleEKIAELEKALAELRKELEeleeeleqlrkeleELSRQISALRKDLARLEAEV 742
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  581 EDLHQvKRDEKSIEVETKTDTSEKPKNQLWLESSTSDIVRDDILLLKNEIQVLQQQNQELKETEEKLRNTNQDLcnqmrq 660
Cdd:TIGR02168  743 EQLEE-RIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLL------ 815
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  661 mvQDFDHDKREAVDRCERTyqqhHEAMKTQIRESLLAKHALEKQQLFEAYERTHLQ-----LRSELDKVNKEMTAVQECY 735
Cdd:TIGR02168  816 --NEEAANLRERLESLERR----IAATERRLEDLEEQIEELSEDIESLAAEIEELEelieeLESELEALLNERASLEEAL 889
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  736 LEVCREKDHLESTLRKtTEKEQQTQEKLLEEREEYVSKLQVELEK--------------KYQDTLMM---------EKSK 792
Cdd:TIGR02168  890 ALLRSELEELSEELRE-LESKRSELRRELEELREKLAQLELRLEGlevridnlqerlseEYSLTLEEaealenkieDDEE 968
                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1622953050  793 WLKDQETDIKQQVEN--EVILAKAHWDKEQKEIKEKLIQQLE--KEWQSKLDQTIKAMKKKTSDRGSQT-DQV 860
Cdd:TIGR02168  969 EARRRLKRLENKIKElgPVNLAAIEEYEELKERYDFLTAQKEdlTEAKETLEEAIEEIDREARERFKDTfDQV 1041
PTZ00121 super family cl31754
MAEBL; Provisional
741-1107 2.60e-09

MAEBL; Provisional


The actual alignment was detected with superfamily member PTZ00121:

Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 62.47  E-value: 2.60e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  741 EKDHLESTLRKTTEKEQQTQEKLLEEREEYVSKLQVELEKKYQDTLMMEKSKWLKDQETDIKQQVENEvilAKAHWDKEQ 820
Cdd:PTZ00121  1429 EKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAK---KKADEAKKA 1505
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  821 KEIKEKLIQQLEKEWQSKLDQTIKAMKKKTSDRGSQTDQVTTSDVISKKEMAIMIEEQKCIIQQHLEQEKDiaiKGAMKK 900
Cdd:PTZ00121  1506 AEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDK---NMALRK 1582
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  901 LEIelelkhceniAKQVEiavqnarQRWLGELPELAEYQALVRAEQKKWEEQHEVsvnkrisfavsEAKEKWKSELENMK 980
Cdd:PTZ00121  1583 AEE----------AKKAE-------EARIEEVMKLYEEEKKMKAEEAKKAEEAKI-----------KAEELKKAEEEKKK 1634
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  981 KNILPGTELEEKihslQRELELKNEEVPVVIRAELAKARSEWNKEKQEEIRRIQEQNEQDYRQFL--DDHRNKINEVLAA 1058
Cdd:PTZ00121  1635 VEQLKKKEAEEK----KKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKkeAEEAKKAEELKKK 1710
                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*....
gi 1622953050 1059 AKEDfmKQKTELLLQKETELQTCLDQSRREwtMQEAKRIQLEIYQYEED 1107
Cdd:PTZ00121  1711 EAEE--KKKAEELKKAEEENKIKAEEAKKE--AEEDKKKAEEAKKDEEE 1755
PRK12704 super family cl36166
phosphodiesterase; Provisional
1210-1396 1.63e-03

phosphodiesterase; Provisional


The actual alignment was detected with superfamily member PRK12704:

Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 43.23  E-value: 1.63e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050 1210 LQETEAEAD---KKKILEIKDlccghcfqELEKAKQECE-DLKGKLEKccrhLQHLERK---HKAVVEKIGEENNKVIEE 1282
Cdd:PRK12704    44 LEEAKKEAEaikKEALLEAKE--------EIHKLRNEFEkELRERRNE----LQKLEKRllqKEENLDRKLELLEKREEE 111
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050 1283 LIEENNDMKNKLEELrtlcktpprslsagaientclpcsggalEELRGQYIKAVKKIKRDMLRYIQESKERAAEMVKAEV 1362
Cdd:PRK12704   112 LEKKEKELEQKQQEL----------------------------EKKEEELEELIEEQLQELERISGLTAEEAKEILLEKV 163
                          170       180       190
                   ....*....|....*....|....*....|....*
gi 1622953050 1363 LRE-RQETARKMRKYYliclqqilqDDGKEGAEKK 1396
Cdd:PRK12704   164 EEEaRHEAAVLIKEIE---------EEAKEEADKK 189
 
Name Accession Description Interval E-value
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
220-860 2.58e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 68.93  E-value: 2.58e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  220 FEGLQQQFLG-ANENSAENMQIIQLQVLNKAKERQLENLVEKLNESECQIRYLNHQLVIIKDEKDGLTLSLresQKLFQN 298
Cdd:TIGR02168  346 LEELKEELESlEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRR---ERLQQE 422
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  299 GKEREIQL-EAQIKALETQIQALKVNEEQMIKKSRTTEMALESLKQQLVDLHHSESLQRAREQHESVVMGLTKKYEEQVL 377
Cdd:TIGR02168  423 IEELLKKLeEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLE 502
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  378 SLQKNLDATVTALKEQEDICSRLKDHVKQLERNQEAIKLEKTEIINRLTRSLEESQKQCAHLLQSGSVQEVAQLQFQLQQ 457
Cdd:TIGR02168  503 GFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIK 582
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  458 AQKAHTMSENMNKALQEELTELKDEISLYESAAKL------GIHPSDSEG---ELNIELTESY--VDLGIKKVNWK---- 522
Cdd:TIGR02168  583 GTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKAlsyllgGVLVVDDLDnalELAKKLRPGYriVTLDGDLVRPGgvit 662
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  523 ---KSKVNSIVQQEDPNEELSKD-----EFILKLKAEVQRLLGSNS--------------MKRRLVSQLQNDLKDCHKKI 580
Cdd:TIGR02168  663 ggsAKTNSSILERRREIEELEEKieeleEKIAELEKALAELRKELEeleeeleqlrkeleELSRQISALRKDLARLEAEV 742
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  581 EDLHQvKRDEKSIEVETKTDTSEKPKNQLWLESSTSDIVRDDILLLKNEIQVLQQQNQELKETEEKLRNTNQDLcnqmrq 660
Cdd:TIGR02168  743 EQLEE-RIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLL------ 815
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  661 mvQDFDHDKREAVDRCERTyqqhHEAMKTQIRESLLAKHALEKQQLFEAYERTHLQ-----LRSELDKVNKEMTAVQECY 735
Cdd:TIGR02168  816 --NEEAANLRERLESLERR----IAATERRLEDLEEQIEELSEDIESLAAEIEELEelieeLESELEALLNERASLEEAL 889
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  736 LEVCREKDHLESTLRKtTEKEQQTQEKLLEEREEYVSKLQVELEK--------------KYQDTLMM---------EKSK 792
Cdd:TIGR02168  890 ALLRSELEELSEELRE-LESKRSELRRELEELREKLAQLELRLEGlevridnlqerlseEYSLTLEEaealenkieDDEE 968
                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1622953050  793 WLKDQETDIKQQVEN--EVILAKAHWDKEQKEIKEKLIQQLE--KEWQSKLDQTIKAMKKKTSDRGSQT-DQV 860
Cdd:TIGR02168  969 EARRRLKRLENKIKElgPVNLAAIEEYEELKERYDFLTAQKEdlTEAKETLEEAIEEIDREARERFKDTfDQV 1041
PTZ00121 PTZ00121
MAEBL; Provisional
741-1107 2.60e-09

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 62.47  E-value: 2.60e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  741 EKDHLESTLRKTTEKEQQTQEKLLEEREEYVSKLQVELEKKYQDTLMMEKSKWLKDQETDIKQQVENEvilAKAHWDKEQ 820
Cdd:PTZ00121  1429 EKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAK---KKADEAKKA 1505
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  821 KEIKEKLIQQLEKEWQSKLDQTIKAMKKKTSDRGSQTDQVTTSDVISKKEMAIMIEEQKCIIQQHLEQEKDiaiKGAMKK 900
Cdd:PTZ00121  1506 AEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDK---NMALRK 1582
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  901 LEIelelkhceniAKQVEiavqnarQRWLGELPELAEYQALVRAEQKKWEEQHEVsvnkrisfavsEAKEKWKSELENMK 980
Cdd:PTZ00121  1583 AEE----------AKKAE-------EARIEEVMKLYEEEKKMKAEEAKKAEEAKI-----------KAEELKKAEEEKKK 1634
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  981 KNILPGTELEEKihslQRELELKNEEVPVVIRAELAKARSEWNKEKQEEIRRIQEQNEQDYRQFL--DDHRNKINEVLAA 1058
Cdd:PTZ00121  1635 VEQLKKKEAEEK----KKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKkeAEEAKKAEELKKK 1710
                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*....
gi 1622953050 1059 AKEDfmKQKTELLLQKETELQTCLDQSRREwtMQEAKRIQLEIYQYEED 1107
Cdd:PTZ00121  1711 EAEE--KKKAEELKKAEEENKIKAEEAKKE--AEEDKKKAEEAKKDEEE 1755
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
241-848 5.37e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 58.02  E-value: 5.37e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  241 IQLQVLN-KAKERQLENLVEKLNESECQIRYLNHQLVIIKDEKDGLTLSLRESQKLFQNGKEREIQLEAQIKALETQIQA 319
Cdd:COG1196    227 AELLLLKlRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIAR 306
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  320 LKVNEEQMIKKSRTTEMALESLKQQLVDLhhSESLQRAREQHESvvmgLTKKYEEQVLSLQKNLDATVTALKEQEDICSR 399
Cdd:COG1196    307 LEERRRELEERLEELEEELAELEEELEEL--EEELEELEEELEE----AEEELEEAEAELAEAEEALLEAEAELAEAEEE 380
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  400 LKDHVKQLERNQEAIKLEKTEIINRLTRSLEESQKQCAHLLQSGSVQEVAQLQFQLQQAQKAhtmsenmnkALQEELTEL 479
Cdd:COG1196    381 LEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEE---------ALEEAAEEE 451
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  480 KDEISLYESAAKlgihpSDSEGELNIELTESYVDLGIKKVNWKKSKVNSIVQQEDPNEELSKDEFILKLKAEVQRLLGsn 559
Cdd:COG1196    452 AELEEEEEALLE-----LLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAG-- 524
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  560 smkrrlvsqlqndlkdchkkieDLHQVKRDEKsiEVETKTDTsekpknqlWLESSTSDIVRDDILLLKNEIQVLQQQNQE 639
Cdd:COG1196    525 ----------------------AVAVLIGVEA--AYEAALEA--------ALAAALQNIVVEDDEVAAAAIEYLKAAKAG 572
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  640 lKETEEKLRNTNQdlcnqmRQMVQDFDHDKREAVDRCERTYQQHHEAMKTQIRESLLAKHALEKQQLfEAYERTHLQLRS 719
Cdd:COG1196    573 -RATFLPLDKIRA------RAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARL-EAALRRAVTLAG 644
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  720 ELDKVNKEMTAVQECYLEVCREKDHLESTLRKTTEKEQQTQEKLLEEREEYVSKLQVELEKKYQDTLMMEKSKWLKDQET 799
Cdd:COG1196    645 RLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEE 724
                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1622953050  800 DIKQQVENEVILAKAHWDKEQKEIKEKLIQQLE-----KEWQSKLDQTIKAMKK 848
Cdd:COG1196    725 ALEEQLEAEREELLEELLEEEELLEEEALEELPeppdlEELERELERLEREIEA 778
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
335-1079 3.33e-07

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 55.51  E-value: 3.33e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  335 EMALESLKQQLVDLHhsESLQRAREQHE-------SVVMGLTKKYEEQVLSLQKNLDATVTALKEQEDICSRLKDHVKQL 407
Cdd:pfam15921   77 ERVLEEYSHQVKDLQ--RRLNESNELHEkqkfylrQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTVHEL 154
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  408 ernqEAIKLEKTEIINRLTRSLEESQKqcAHLLQSGSVQE-----VAQLQFQLQQAQKAHTMS----ENMNKALQEELTE 478
Cdd:pfam15921  155 ----EAAKCLKEDMLEDSNTQIEQLRK--MMLSHEGVLQEirsilVDFEEASGKKIYEHDSMStmhfRSLGSAISKILRE 228
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  479 LKDEIS-----LYESAAKLGIHPSDSEGELNIEL-----------TESYVDLG--IKKVNWKKSKVNSIVQQEDPNEELS 540
Cdd:pfam15921  229 LDTEISylkgrIFPVEDQLEALKSESQNKIELLLqqhqdrieqliSEHEVEITglTEKASSARSQANSIQSQLEIIQEQA 308
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  541 KDEfilklkaevqrllgsNSMKRR-------LVSQLQNDLKDCHKKIEDlhQVKRDEKSIEVETKTDTSEKP-KNQLWLE 612
Cdd:pfam15921  309 RNQ---------------NSMYMRqlsdlesTVSQLRSELREAKRMYED--KIEELEKQLVLANSELTEARTeRDQFSQE 371
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  613 SSTSDivrDDillLKNEIQVLQQQNQELK-ETEEKLRNTNQDLCNQMrqmvqDFDHDKREAVDRcertyqqhheAMKTQI 691
Cdd:pfam15921  372 SGNLD---DQ---LQKLLADLHKREKELSlEKEQNKRLWDRDTGNSI-----TIDHLRRELDDR----------NMEVQR 430
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  692 RESLLAKHALEKQQLFEayerthlqlrseldkvnKEMTAVQ---ECYLEVCREKDHLEST---LRKTTEkEQQTQEKLLE 765
Cdd:pfam15921  431 LEALLKAMKSECQGQME-----------------RQMAAIQgknESLEKVSSLTAQLESTkemLRKVVE-ELTAKKMTLE 492
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  766 EREEYVSKLQVELEKKYQDTLMMEKSKWLKDQETDIKQQVENEVILAKAHWDKEQKEIKEKLIQQLEKEWQSK-LDQTIK 844
Cdd:pfam15921  493 SSERTVSDLTASLQEKERAIEATNAEITKLRSRVDLKLQELQHLKNEGDHLRNVQTECEALKLQMAEKDKVIEiLRQQIE 572
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  845 AMKKKTSDRGSQTDQVttsdVISKKEMAIMIEEQKCIIQQH--LEQEKDIAIKGAMKKL-EIELELKHCENIAKQVEIAV 921
Cdd:pfam15921  573 NMTQLVGQHGRTAGAM----QVEKAQLEKEINDRRLELQEFkiLKDKKDAKIRELEARVsDLELEKVKLVNAGSERLRAV 648
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  922 QNARQrwlgELPELAEYQALVRAEQKKWEEQHEVsvnkrisfavseAKEKWKSELENMKKNIlpgTELEEKIHSLQRELE 1001
Cdd:pfam15921  649 KDIKQ----ERDQLLNEVKTSRNELNSLSEDYEV------------LKRNFRNKSEEMETTT---NKLKMQLKSAQSELE 709
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050 1002 -----LKNEE--------VPVVIRAELAKARSEWNKeKQEEIRRIQE--QNEQDYRQFLDDHRNKINEVLA--AAKEDFM 1064
Cdd:pfam15921  710 qtrntLKSMEgsdghamkVAMGMQKQITAKRGQIDA-LQSKIQFLEEamTNANKEKHFLKEEKNKLSQELStvATEKNKM 788
                          810
                   ....*....|....*
gi 1622953050 1065 KQKTELLLQKETELQ 1079
Cdd:pfam15921  789 AGELEVLRSQERRLK 803
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
802-1107 6.05e-05

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 47.81  E-value: 6.05e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  802 KQQVENEVILAKAHWDKEQKEIKEKLIQQ-LEKEWQSKLDQTIKAMKKKTSDRGSQTDQVTTSDVISKKEMAIMIEEQKC 880
Cdd:pfam17380  263 QTMTENEFLNQLLHIVQHQKAVSERQQQEkFEKMEQERLRQEKEEKAREVERRRKLEEAEKARQAEMDRQAAIYAEQERM 342
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  881 IIQQHLEQEKdiaIKGAMKKLEIELelkhceniAKQVEIAVQNARQRWLGELP--------------ELAEYQALVRAEQ 946
Cdd:pfam17380  343 AMERERELER---IRQEERKRELER--------IRQEEIAMEISRMRELERLQmerqqknervrqelEAARKVKILEEER 411
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  947 KKWEEQHEVSVNKrISFAVSEAKEKWKSELENMKKNILPGTELEEKIHSLQRELELKNEEVPVVIRAELAKARSEwNKEK 1026
Cdd:pfam17380  412 QRKIQQQKVEMEQ-IRAEQEEARQREVRRLEEERAREMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRD-RKRA 489
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050 1027 QEEIRRIQEQNEQDYRQFLDDHRNKiNEVLAAAKEDFMKQKTELLLQKETElqtclDQSRREWTMQEAKRIQLEIYQYEE 1106
Cdd:pfam17380  490 EEQRRKILEKELEERKQAMIEEERK-RKLLEKEMEERQKAIYEEERRREAE-----EERRKQQEMEERRRIQEQMRKATE 563

                   .
gi 1622953050 1107 D 1107
Cdd:pfam17380  564 E 564
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
625-1134 4.24e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 45.31  E-value: 4.24e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  625 LLKNEIQVLQQQNQELKETEEKLRNTNQDLCNQMRQMVQDFDHDKREAVDRCERTYQQHHEamktqiRESLLAKHALEKQ 704
Cdd:COG1196    264 ELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEE------LAELEEELEELEE 337
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  705 QLfeayerthLQLRSELDKVNKEMTAVQEcylevcrEKDHLESTLRKTTEKEQQTQEKLLEEREEYVSKLQVELE-KKYQ 783
Cdd:COG1196    338 EL--------EELEEELEEAEEELEEAEA-------ELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAElAAQL 402
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  784 DTLMMEKSKWLKDQETDIKQQVENEVILAKAhwdkEQKEIKEKLIQQLEKEWQSKLDQTIKAMKKKTSDRGSQTDQVTTS 863
Cdd:COG1196    403 EELEEAEEALLERLERLEEELEELEEALAEL----EEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAA 478
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  864 DVISKKEMAIMIEEQKCIIQQHLEQEKDIAIKGAMKKLEIELELKHCENIAKQVEIAVQNARQRWLGELpeLAEYQALVR 943
Cdd:COG1196    479 LAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAA--LQNIVVEDD 556
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  944 AEQKKWEEQHEVSVNKRISF------AVSEAKEKWKSELENMKKNILPGTELEEKIHSLQRELELKNEEVPVVIRAELAK 1017
Cdd:COG1196    557 EVAAAAIEYLKAAKAGRATFlpldkiRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAAL 636
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050 1018 ARSEwnKEKQEEIRRIQEQNEQDYRQFLDDHRNKINEVLAAAKEDFMKQKTELLLQKETELQTCLDQSRREWTMQEAKRI 1097
Cdd:COG1196    637 RRAV--TLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEE 714
                          490       500       510
                   ....*....|....*....|....*....|....*..
gi 1622953050 1098 QLEIYQYEEDILTVLGVLLRDTQKEHVSDFEDKQLLE 1134
Cdd:COG1196    715 ERLEEELEEEALEEQLEAEREELLEELLEEEELLEEE 751
PRK12704 PRK12704
phosphodiesterase; Provisional
1210-1396 1.63e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 43.23  E-value: 1.63e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050 1210 LQETEAEAD---KKKILEIKDlccghcfqELEKAKQECE-DLKGKLEKccrhLQHLERK---HKAVVEKIGEENNKVIEE 1282
Cdd:PRK12704    44 LEEAKKEAEaikKEALLEAKE--------EIHKLRNEFEkELRERRNE----LQKLEKRllqKEENLDRKLELLEKREEE 111
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050 1283 LIEENNDMKNKLEELrtlcktpprslsagaientclpcsggalEELRGQYIKAVKKIKRDMLRYIQESKERAAEMVKAEV 1362
Cdd:PRK12704   112 LEKKEKELEQKQQEL----------------------------EKKEEELEELIEEQLQELERISGLTAEEAKEILLEKV 163
                          170       180       190
                   ....*....|....*....|....*....|....*
gi 1622953050 1363 LRE-RQETARKMRKYYliclqqilqDDGKEGAEKK 1396
Cdd:PRK12704   164 EEEaRHEAAVLIKEIE---------EEAKEEADKK 189
PRK12704 PRK12704
phosphodiesterase; Provisional
700-849 1.78e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 42.84  E-value: 1.78e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  700 ALEKQQLFEAYERTHlQLRSELDKVNKEMT---AVQECYLEvcREKDHLESTLRKTTEKEQ--QTQEKLLEEREEYVSKL 774
Cdd:PRK12704    53 AIKKEALLEAKEEIH-KLRNEFEKELRERRnelQKLEKRLL--QKEENLDRKLELLEKREEelEKKEKELEQKQQELEKK 129
                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1622953050  775 QVELEKKYQdtlmmekskwlkdqetdiKQQVENEVIlakAHWDKEqkEIKEKLIQQLEKEWQSKLDQTIKAMKKK 849
Cdd:PRK12704   130 EEELEELIE------------------EQLQELERI---SGLTAE--EAKEILLEKVEEEARHEAAVLIKEIEEE 181
 
Name Accession Description Interval E-value
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
220-860 2.58e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 68.93  E-value: 2.58e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  220 FEGLQQQFLG-ANENSAENMQIIQLQVLNKAKERQLENLVEKLNESECQIRYLNHQLVIIKDEKDGLTLSLresQKLFQN 298
Cdd:TIGR02168  346 LEELKEELESlEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRR---ERLQQE 422
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  299 GKEREIQL-EAQIKALETQIQALKVNEEQMIKKSRTTEMALESLKQQLVDLHHSESLQRAREQHESVVMGLTKKYEEQVL 377
Cdd:TIGR02168  423 IEELLKKLeEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLE 502
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  378 SLQKNLDATVTALKEQEDICSRLKDHVKQLERNQEAIKLEKTEIINRLTRSLEESQKQCAHLLQSGSVQEVAQLQFQLQQ 457
Cdd:TIGR02168  503 GFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIK 582
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  458 AQKAHTMSENMNKALQEELTELKDEISLYESAAKL------GIHPSDSEG---ELNIELTESY--VDLGIKKVNWK---- 522
Cdd:TIGR02168  583 GTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKAlsyllgGVLVVDDLDnalELAKKLRPGYriVTLDGDLVRPGgvit 662
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  523 ---KSKVNSIVQQEDPNEELSKD-----EFILKLKAEVQRLLGSNS--------------MKRRLVSQLQNDLKDCHKKI 580
Cdd:TIGR02168  663 ggsAKTNSSILERRREIEELEEKieeleEKIAELEKALAELRKELEeleeeleqlrkeleELSRQISALRKDLARLEAEV 742
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  581 EDLHQvKRDEKSIEVETKTDTSEKPKNQLWLESSTSDIVRDDILLLKNEIQVLQQQNQELKETEEKLRNTNQDLcnqmrq 660
Cdd:TIGR02168  743 EQLEE-RIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLL------ 815
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  661 mvQDFDHDKREAVDRCERTyqqhHEAMKTQIRESLLAKHALEKQQLFEAYERTHLQ-----LRSELDKVNKEMTAVQECY 735
Cdd:TIGR02168  816 --NEEAANLRERLESLERR----IAATERRLEDLEEQIEELSEDIESLAAEIEELEelieeLESELEALLNERASLEEAL 889
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  736 LEVCREKDHLESTLRKtTEKEQQTQEKLLEEREEYVSKLQVELEK--------------KYQDTLMM---------EKSK 792
Cdd:TIGR02168  890 ALLRSELEELSEELRE-LESKRSELRRELEELREKLAQLELRLEGlevridnlqerlseEYSLTLEEaealenkieDDEE 968
                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1622953050  793 WLKDQETDIKQQVEN--EVILAKAHWDKEQKEIKEKLIQQLE--KEWQSKLDQTIKAMKKKTSDRGSQT-DQV 860
Cdd:TIGR02168  969 EARRRLKRLENKIKElgPVNLAAIEEYEELKERYDFLTAQKEdlTEAKETLEEAIEEIDREARERFKDTfDQV 1041
PTZ00121 PTZ00121
MAEBL; Provisional
741-1107 2.60e-09

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 62.47  E-value: 2.60e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  741 EKDHLESTLRKTTEKEQQTQEKLLEEREEYVSKLQVELEKKYQDTLMMEKSKWLKDQETDIKQQVENEvilAKAHWDKEQ 820
Cdd:PTZ00121  1429 EKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAK---KKADEAKKA 1505
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  821 KEIKEKLIQQLEKEWQSKLDQTIKAMKKKTSDRGSQTDQVTTSDVISKKEMAIMIEEQKCIIQQHLEQEKDiaiKGAMKK 900
Cdd:PTZ00121  1506 AEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDK---NMALRK 1582
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  901 LEIelelkhceniAKQVEiavqnarQRWLGELPELAEYQALVRAEQKKWEEQHEVsvnkrisfavsEAKEKWKSELENMK 980
Cdd:PTZ00121  1583 AEE----------AKKAE-------EARIEEVMKLYEEEKKMKAEEAKKAEEAKI-----------KAEELKKAEEEKKK 1634
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  981 KNILPGTELEEKihslQRELELKNEEVPVVIRAELAKARSEWNKEKQEEIRRIQEQNEQDYRQFL--DDHRNKINEVLAA 1058
Cdd:PTZ00121  1635 VEQLKKKEAEEK----KKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKkeAEEAKKAEELKKK 1710
                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*....
gi 1622953050 1059 AKEDfmKQKTELLLQKETELQTCLDQSRREwtMQEAKRIQLEIYQYEED 1107
Cdd:PTZ00121  1711 EAEE--KKKAEELKKAEEENKIKAEEAKKE--AEEDKKKAEEAKKDEEE 1755
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
253-845 1.28e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 60.07  E-value: 1.28e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  253 QLENLVEKLNESECQIRYLNHQLVIIKDEKDGLTLSLRESQKLFQNGKER--EIQ-----LEAQIKALETQIQALKVNEE 325
Cdd:TIGR02168  233 RLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEieELQkelyaLANEISRLEQQKQILRERLA 312
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  326 QMIKKSRTTEMALESLKQQLVDLhhSESLQRAREQHESvVMGLTKKYEEQVLSLQKNLDATVTALKEQEDICSRLKDHVK 405
Cdd:TIGR02168  313 NLERQLEELEAQLEELESKLDEL--AEELAELEEKLEE-LKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVA 389
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  406 QLERNQEAIKLEKTEI---INRLTRSLEESQKQCAHLLQSGSVQEVAQLQFQLQQAQKAHTMSENMNKALQEELTELKDE 482
Cdd:TIGR02168  390 QLELQIASLNNEIERLearLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREE 469
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  483 ISLYESA---AKLGIHPSDSEGELNIELTESYVDL--GIKKVNWKKSKVNSIVQQ------------------------- 532
Cdd:TIGR02168  470 LEEAEQAldaAERELAQLQARLDSLERLQENLEGFseGVKALLKNQSGLSGILGVlselisvdegyeaaieaalggrlqa 549
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  533 -EDPNEELSKDEF------------ILKLKAEVQRLLGSNSMKRRL----VSQLQNDLKDCHKKI--------------E 581
Cdd:TIGR02168  550 vVVENLNAAKKAIaflkqnelgrvtFLPLDSIKGTEIQGNDREILKniegFLGVAKDLVKFDPKLrkalsyllggvlvvD 629
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  582 DLHQVKRDEKSIEVE----TKTDT-----------SEKPKNQLWLESSTSDIVR-------DDILLLKNEIQVLQQQNQE 639
Cdd:TIGR02168  630 DLDNALELAKKLRPGyrivTLDGDlvrpggvitggSAKTNSSILERRREIEELEekieeleEKIAELEKALAELRKELEE 709
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  640 LKETEEKLRNTNQDLCNQMRQMVQDFDHDKREAVDRCERTYQQHHE---------AMKTQIRESLLAKHALEK-----QQ 705
Cdd:TIGR02168  710 LEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKElteleaeieELEERLEEAEEELAEAEAeieelEA 789
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  706 LFEAYERTHLQLRSELDKVNKEMTAVQECYLEVCREKDHLESTLRKtTEKEQQTQEKLLEEREEYVSKLQVELEKkyQDT 785
Cdd:TIGR02168  790 QIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAA-TERRLEDLEEQIEELSEDIESLAAEIEE--LEE 866
                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  786 LMMEKSKWLKdQETDIKQQVENEVILAKAHWDKEQKEIKEKLIQQLEKEWQSKLDQTIKA 845
Cdd:TIGR02168  867 LIEELESELE-ALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLA 925
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
305-1077 4.05e-08

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 58.52  E-value: 4.05e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  305 QLEAQIKALETQIQALKVNEEQMikksRTTEMALESLKQQLVDLHHSESLQRAREQHESVVMGLTKKYEEQVLSL---QK 381
Cdd:TIGR00606  180 SATRYIKALETLRQVRQTQGQKV----QEHQMELKYLKQYKEKACEIRDQITSKEAQLESSREIVKSYENELDPLknrLK 255
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  382 NLDATVTALKEQEDICSRLKDHVKQLERNQEAIKLEKTEIInrltRSLEESQKQCAHLLQSgsvqEVAQLQFQLQQAQKA 461
Cdd:TIGR00606  256 EIEHNLSKIMKLDNEIKALKSRKKQMEKDNSELELKMEKVF----QGTDEQLNDLYHNHQR----TVREKERELVDCQRE 327
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  462 HTMSENMNKALQEELTELKDEISLYESAAKLgIHPSDSEGELNIELTESYVDLGikkvnwkkskvnsiVQQEDPNEELSK 541
Cdd:TIGR00606  328 LEKLNKERRLLNQEKTELLVEQGRLQLQADR-HQEHIRARDSLIQSLATRLELD--------------GFERGPFSERQI 392
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  542 DEFIlklKAEVQRLLGSNSMKRRLVSQLQNDLKDCHKKIEDLhQVKRDEKSIEVETKTDTSEKPKNQL--------WLES 613
Cdd:TIGR00606  393 KNFH---TLVIERQEDEAKTAAQLCADLQSKERLKQEQADEI-RDEKKGLGRTIELKKEILEKKQEELkfvikelqQLEG 468
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  614 STSDIVRDDILLLKNEIQVLQQQNQELKETEEK----LRNTNQDLCNQMRQMVQDFDHDKREAVDRCERTYQQHHEAMKT 689
Cdd:TIGR00606  469 SSDRILELDQELRKAERELSKAEKNSLTETLKKevksLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEMLTKDKMDKD 548
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  690 QIRESLLAKHALEKQQLFEAY------ERTHLQLRSELDKVNKEMTAVQECYLEVCREKDHLESTLRKTTEKEQQTQEKL 763
Cdd:TIGR00606  549 EQIRKIKSRHSDELTSLLGYFpnkkqlEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKL 628
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  764 L-----EEREEYVSKLQVELEKKYQDTLMMEKSKWLKDQ---ETDIKQQVENEVILAKAHWDKEQKEIKEKLiQQLEKEW 835
Cdd:TIGR00606  629 FdvcgsQDEESDLERLKEEIEKSSKQRAMLAGATAVYSQfitQLTDENQSCCPVCQRVFQTEAELQEFISDL-QSKLRLA 707
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  836 QSKLDQTIKAMKKKTSDRgsqtdqvttsdviskKEMAIMIEEQKCIIQQHLEQEKDIAIKGAMKKLEIELELKHCENIAK 915
Cdd:TIGR00606  708 PDKLKSTESELKKKEKRR---------------DEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQET 772
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  916 QVE--IAVQNARQRWLGELPELAEYQALVRAEQKKWEEQHEVSVNKRISFAVSEAKEKWKSELENMKKNILPGTEL---- 989
Cdd:TIGR00606  773 LLGtiMPEEESAKVCLTDVTIMERFQMELKDVERKIAQQAAKLQGSDLDRTVQQVNQEKQEKQHELDTVVSKIELNrkli 852
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  990 ---EEKIHSLQREL-ELKNEEVPVvirAELAKARSEWNKEKQEEIRRIQEQNEQdyrqfLDDHRNKINEvLAAAKEDFMK 1065
Cdd:TIGR00606  853 qdqQEQIQHLKSKTnELKSEKLQI---GTNLQRRQQFEEQLVELSTEVQSLIRE-----IKDAKEQDSP-LETFLEKDQQ 923
                          810
                   ....*....|..
gi 1622953050 1066 QKTELLLQKETE 1077
Cdd:TIGR00606  924 EKEELISSKETS 935
PTZ00121 PTZ00121
MAEBL; Provisional
669-1300 4.11e-08

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 58.61  E-value: 4.11e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  669 KREAVDRCERTYQQHHEAMKTQIRESLLAKHALEKQQLFEAYERTHLQLRSELDKVNKEMTAVQECYLE--VCREKDHLE 746
Cdd:PTZ00121  1195 KAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAhfARRQAAIKA 1274
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  747 STLRKTTEKEQQTQEKLLEEREEYVSKLQV-ELEKKYQDTlmmEKSKWLKDQETDIKQqvenevilaKAHWDKEQKEIKE 825
Cdd:PTZ00121  1275 EEARKADELKKAEEKKKADEAKKAEEKKKAdEAKKKAEEA---KKADEAKKKAEEAKK---------KADAAKKKAEEAK 1342
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  826 KLIQQLEKEWQSKLDQTIKAMKKKTSDRGSQTDQVTTSDVISKK-EMAIMIEEQKCIIQQHLEQEKDIAIKGAMKKLEIE 904
Cdd:PTZ00121  1343 KAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKaEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADE 1422
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  905 LElKHCENIAKQVEIAVQNARQRWLGELPELAEYQALVRAEQKKWEEQHEVSVNKRISFAVSEAKEKWKSELENMKKnil 984
Cdd:PTZ00121  1423 AK-KKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKK--- 1498
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  985 pGTELEEKIHSLQRELELKNEEVPVviRAELAKARSEwnKEKQEEIRRIQEQNEQDyrqflddHRNKINEVLAAAKEDFM 1064
Cdd:PTZ00121  1499 -ADEAKKAAEAKKKADEAKKAEEAK--KADEAKKAEE--AKKADEAKKAEEKKKAD-------ELKKAEELKKAEEKKKA 1566
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050 1065 KQKtelllQKETELQTCLDQSRREWTMQEAKRIQLEIYQYEEDiLTVLGVLLRDTQKEHVSDFEDKQLLEIMSTCSSKWM 1144
Cdd:PTZ00121  1567 EEA-----KKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEE-KKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKK 1640
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050 1145 SVQYFEKLKGCIQKAFQDTLPLLVENA-DPQWEKRNMAELSKDSASRSTGQGVPGPAAGHHAQPLALQETEAEADKK--- 1220
Cdd:PTZ00121  1641 KEAEEKKKAEELKKAEEENKIKAAEEAkKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKaee 1720
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050 1221 --KILEIKDLCCGHCFQELEKAKQECEDLKgKLEKCCRHLQHLERKHKAVVEKIGEENNKVIEELIEEnNDMKNKLEELR 1298
Cdd:PTZ00121  1721 lkKAEEENKIKAEEAKKEAEEDKKKAEEAK-KDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDE-EDEKRRMEVDK 1798

                   ..
gi 1622953050 1299 TL 1300
Cdd:PTZ00121  1799 KI 1800
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
241-848 5.37e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 58.02  E-value: 5.37e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  241 IQLQVLN-KAKERQLENLVEKLNESECQIRYLNHQLVIIKDEKDGLTLSLRESQKLFQNGKEREIQLEAQIKALETQIQA 319
Cdd:COG1196    227 AELLLLKlRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIAR 306
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  320 LKVNEEQMIKKSRTTEMALESLKQQLVDLhhSESLQRAREQHESvvmgLTKKYEEQVLSLQKNLDATVTALKEQEDICSR 399
Cdd:COG1196    307 LEERRRELEERLEELEEELAELEEELEEL--EEELEELEEELEE----AEEELEEAEAELAEAEEALLEAEAELAEAEEE 380
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  400 LKDHVKQLERNQEAIKLEKTEIINRLTRSLEESQKQCAHLLQSGSVQEVAQLQFQLQQAQKAhtmsenmnkALQEELTEL 479
Cdd:COG1196    381 LEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEE---------ALEEAAEEE 451
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  480 KDEISLYESAAKlgihpSDSEGELNIELTESYVDLGIKKVNWKKSKVNSIVQQEDPNEELSKDEFILKLKAEVQRLLGsn 559
Cdd:COG1196    452 AELEEEEEALLE-----LLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAG-- 524
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  560 smkrrlvsqlqndlkdchkkieDLHQVKRDEKsiEVETKTDTsekpknqlWLESSTSDIVRDDILLLKNEIQVLQQQNQE 639
Cdd:COG1196    525 ----------------------AVAVLIGVEA--AYEAALEA--------ALAAALQNIVVEDDEVAAAAIEYLKAAKAG 572
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  640 lKETEEKLRNTNQdlcnqmRQMVQDFDHDKREAVDRCERTYQQHHEAMKTQIRESLLAKHALEKQQLfEAYERTHLQLRS 719
Cdd:COG1196    573 -RATFLPLDKIRA------RAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARL-EAALRRAVTLAG 644
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  720 ELDKVNKEMTAVQECYLEVCREKDHLESTLRKTTEKEQQTQEKLLEEREEYVSKLQVELEKKYQDTLMMEKSKWLKDQET 799
Cdd:COG1196    645 RLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEE 724
                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1622953050  800 DIKQQVENEVILAKAHWDKEQKEIKEKLIQQLE-----KEWQSKLDQTIKAMKK 848
Cdd:COG1196    725 ALEEQLEAEREELLEELLEEEELLEEEALEELPeppdlEELERELERLEREIEA 778
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
248-1054 1.46e-07

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 56.61  E-value: 1.46e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  248 KAKERQLENLVEKLNESECQIRYLNHQLVIIKDEKDGLTLSLRESQKLFQNGKEREI-QLEAQIKALETQIQALKVNEEQ 326
Cdd:TIGR02169  240 EAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIgELEAEIASLERSIAEKERELED 319
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  327 MIKKSRTTEMALESLKQQLVDLhhSESLQRAREQHESVvmgltkkyEEQVLSLQKNLDATVTALKEQEDICSRLKDHVKQ 406
Cdd:TIGR02169  320 AEERLAKLEAEIDKLLAEIEEL--EREIEEERKRRDKL--------TEEYAELKEELEDLRAELEEVDKEFAETRDELKD 389
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  407 LERNQEAIKLEKTEIINRLTRSLEESQKQCAHLLQsgsvqevaqlqfqlqqaqkahtmSENMNKALQEELTELKDEisLY 486
Cdd:TIGR02169  390 YREKLEKLKREINELKRELDRLQEELQRLSEELAD-----------------------LNAAIAGIEAKINELEEE--KE 444
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  487 ESAAKLgihpsdSEGELNIELTESYVDLGIKKVNWKKSKVNSIvqqedpNEELSKDEF-ILKLKAEVQRLLGSNSMKRRL 565
Cdd:TIGR02169  445 DKALEI------KKQEWKLEQLAADLSKYEQELYDLKEEYDRV------EKELSKLQReLAEAEAQARASEERVRGGRAV 512
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  566 VSQLQNDLKDCHKKIEDLHQVkrdeksievetktdtseKPKNQLWLESSTSD----IVRDDILLLKNEIQVLQQQNQElk 641
Cdd:TIGR02169  513 EEVLKASIQGVHGTVAQLGSV-----------------GERYATAIEVAAGNrlnnVVVEDDAVAKEAIELLKRRKAG-- 573
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  642 eteeklRNTNQDLcNQMRQMVQDFDHDKRE-----AVD--RCERTYQ-------------QHHEAMKT---QIRESLLAK 698
Cdd:TIGR02169  574 ------RATFLPL-NKMRDERRDLSILSEDgvigfAVDlvEFDPKYEpafkyvfgdtlvvEDIEAARRlmgKYRMVTLEG 646
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  699 HALEK-------------QQLFEAYERTHLQ-LRSELDKVNKEMTAVQECYLEVCREKDHLESTLRKTT----------- 753
Cdd:TIGR02169  647 ELFEKsgamtggsraprgGILFSRSEPAELQrLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASrkigeiekeie 726
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  754 --EKEQQTQEKLLEEREEYVSKLQVELEKKyqDTLMMEKSKWLKDQETDIkQQVENEVILAKAHWDKEQKEIKEKLIQQL 831
Cdd:TIGR02169  727 qlEQEEEKLKERLEELEEDLSSLEQEIENV--KSELKELEARIEELEEDL-HKLEEALNDLEARLSHSRIPEIQAELSKL 803
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  832 EKEwQSKLDQTIKAMKKKTSDRgSQTDQVTTSDVISKKEMAIMIEEQKCIIQQhlEQEKDIAIKGAMKKLEIELELKHCE 911
Cdd:TIGR02169  804 EEE-VSRIEARLREIEQKLNRL-TLEKEYLEKEIQELQEQRIDLKEQIKSIEK--EIENLNGKKEELEEELEELEAALRD 879
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  912 NIAKQVEIAVQNARQRwlgelpelAEYQALVRAEQK-KWEEQHEVSVNKRISFAVSEAKEKwKSELENMKKNILPGTELE 990
Cdd:TIGR02169  880 LESRLGDLKKERDELE--------AQLRELERKIEElEAQIEKKRKRLSELKAKLEALEEE-LSEIEDPKGEDEEIPEEE 950
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  991 EKIHSLQRELELKNEEV----PVVIRA------------ELAKARSEWNKEKQEEIRRIQEQNEQDYRQFLDDHrNKINE 1054
Cdd:TIGR02169  951 LSLEDVQAELQRVEEEIralePVNMLAiqeyeevlkrldELKEKRAKLEEERKAILERIEEYEKKKREVFMEAF-EAINE 1029
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
335-1079 3.33e-07

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 55.51  E-value: 3.33e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  335 EMALESLKQQLVDLHhsESLQRAREQHE-------SVVMGLTKKYEEQVLSLQKNLDATVTALKEQEDICSRLKDHVKQL 407
Cdd:pfam15921   77 ERVLEEYSHQVKDLQ--RRLNESNELHEkqkfylrQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTVHEL 154
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  408 ernqEAIKLEKTEIINRLTRSLEESQKqcAHLLQSGSVQE-----VAQLQFQLQQAQKAHTMS----ENMNKALQEELTE 478
Cdd:pfam15921  155 ----EAAKCLKEDMLEDSNTQIEQLRK--MMLSHEGVLQEirsilVDFEEASGKKIYEHDSMStmhfRSLGSAISKILRE 228
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  479 LKDEIS-----LYESAAKLGIHPSDSEGELNIEL-----------TESYVDLG--IKKVNWKKSKVNSIVQQEDPNEELS 540
Cdd:pfam15921  229 LDTEISylkgrIFPVEDQLEALKSESQNKIELLLqqhqdrieqliSEHEVEITglTEKASSARSQANSIQSQLEIIQEQA 308
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  541 KDEfilklkaevqrllgsNSMKRR-------LVSQLQNDLKDCHKKIEDlhQVKRDEKSIEVETKTDTSEKP-KNQLWLE 612
Cdd:pfam15921  309 RNQ---------------NSMYMRqlsdlesTVSQLRSELREAKRMYED--KIEELEKQLVLANSELTEARTeRDQFSQE 371
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  613 SSTSDivrDDillLKNEIQVLQQQNQELK-ETEEKLRNTNQDLCNQMrqmvqDFDHDKREAVDRcertyqqhheAMKTQI 691
Cdd:pfam15921  372 SGNLD---DQ---LQKLLADLHKREKELSlEKEQNKRLWDRDTGNSI-----TIDHLRRELDDR----------NMEVQR 430
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  692 RESLLAKHALEKQQLFEayerthlqlrseldkvnKEMTAVQ---ECYLEVCREKDHLEST---LRKTTEkEQQTQEKLLE 765
Cdd:pfam15921  431 LEALLKAMKSECQGQME-----------------RQMAAIQgknESLEKVSSLTAQLESTkemLRKVVE-ELTAKKMTLE 492
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  766 EREEYVSKLQVELEKKYQDTLMMEKSKWLKDQETDIKQQVENEVILAKAHWDKEQKEIKEKLIQQLEKEWQSK-LDQTIK 844
Cdd:pfam15921  493 SSERTVSDLTASLQEKERAIEATNAEITKLRSRVDLKLQELQHLKNEGDHLRNVQTECEALKLQMAEKDKVIEiLRQQIE 572
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  845 AMKKKTSDRGSQTDQVttsdVISKKEMAIMIEEQKCIIQQH--LEQEKDIAIKGAMKKL-EIELELKHCENIAKQVEIAV 921
Cdd:pfam15921  573 NMTQLVGQHGRTAGAM----QVEKAQLEKEINDRRLELQEFkiLKDKKDAKIRELEARVsDLELEKVKLVNAGSERLRAV 648
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  922 QNARQrwlgELPELAEYQALVRAEQKKWEEQHEVsvnkrisfavseAKEKWKSELENMKKNIlpgTELEEKIHSLQRELE 1001
Cdd:pfam15921  649 KDIKQ----ERDQLLNEVKTSRNELNSLSEDYEV------------LKRNFRNKSEEMETTT---NKLKMQLKSAQSELE 709
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050 1002 -----LKNEE--------VPVVIRAELAKARSEWNKeKQEEIRRIQE--QNEQDYRQFLDDHRNKINEVLA--AAKEDFM 1064
Cdd:pfam15921  710 qtrntLKSMEgsdghamkVAMGMQKQITAKRGQIDA-LQSKIQFLEEamTNANKEKHFLKEEKNKLSQELStvATEKNKM 788
                          810
                   ....*....|....*
gi 1622953050 1065 KQKTELLLQKETELQ 1079
Cdd:pfam15921  789 AGELEVLRSQERRLK 803
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
227-442 4.55e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 50.92  E-value: 4.55e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  227 FLGANENSAENMQIIQLQVLNKAKERQLENLVEKLNESECQIRYLNHQLVIIKDEKDGLTLSLRESQKLFQNGKEREIQL 306
Cdd:COG4942      9 LLLALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAEL 88
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  307 EAQIKALETQIQALKVNEEQMI----KKSRTTEMAL----ESLKQQLVDLHHSESLQRAREQHesvvmgltkkyEEQVLS 378
Cdd:COG4942     89 EKEIAELRAELEAQKEELAELLralyRLGRQPPLALllspEDFLDAVRRLQYLKYLAPARREQ-----------AEELRA 157
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1622953050  379 LQKNLDATVTALKEQEDICSRLKDHVKQLERNQEAIKLEKTEIINRLTRSLEESQKQCAHLLQS 442
Cdd:COG4942    158 DLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQE 221
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
290-774 4.77e-06

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 51.31  E-value: 4.77e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  290 RESQKLF-QNGKEREIQLEaQIKALETQIQALKVNEE---QMIKKSRTTEMALESLKQQLVDL-HHSESLQRA------- 357
Cdd:COG4717     53 KEADELFkPQGRKPELNLK-ELKELEEELKEAEEKEEeyaELQEELEELEEELEELEAELEELrEELEKLEKLlqllply 131
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  358 --REQHESVVMGLTKKYEEqvlsLQKNLDATVTALKEQEDICSRLKDHVKQLERNQEAIKLEKTEIINRLTRSLEESQKQ 435
Cdd:COG4717    132 qeLEALEAELAELPERLEE----LEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQR 207
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  436 CAHLLQS-GSVQEVAQLQFQLQQAQKAHTMSENMNKALQEELTELKDEISLyesAAKLGIHPSDSEGELNIeLTESYVDL 514
Cdd:COG4717    208 LAELEEElEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIAAAL---LALLGLGGSLLSLILTI-AGVLFLVL 283
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  515 GIKKVNWKKSKVNSIVQQEDPNEELSKDEFILKLKAEVQRLLGSNSMKRRLVSQLQNDLKDchkKIEDLHQVKRDEKSIE 594
Cdd:COG4717    284 GLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLD---RIEELQELLREAEELE 360
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  595 VETKTDTSEKPKNQLWLESSTSDivRDDILLLKNEIQVLQQQNQELKETEEKLRNTNQDLCNQMRQMVQDFDHDKREAVD 674
Cdd:COG4717    361 EELQLEELEQEIAALLAEAGVED--EEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEELEELE 438
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  675 RCERTYQQHHEAMKTQIRESLLAKHALEKQQLFEAYERTHLQLRSELDKVNKEMTAVQecylevcrekdHLESTLRKTTE 754
Cdd:COG4717    439 EELEELEEELEELREELAELEAELEQLEEDGELAELLQELEELKAELRELAEEWAALK-----------LALELLEEARE 507
                          490       500
                   ....*....|....*....|.
gi 1622953050  755 K-EQQTQEKLLEEREEYVSKL 774
Cdd:COG4717    508 EyREERLPPVLERASEYFSRL 528
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
371-1131 1.34e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 50.44  E-value: 1.34e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  371 KYEEQVLSLQKNLDATVTALKeqedicsRLKDHVKQLERNQEAIKL--EKTEIINRLTRSLEESQKQCahllqsgSVQEV 448
Cdd:TIGR02168  169 KYKERRKETERKLERTRENLD-------RLEDILNELERQLKSLERqaEKAERYKELKAELRELELAL-------LVLRL 234
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  449 AQLQFQLQQAQKAHTMSENMNKALQEELTELKDEIslyeSAAKLGIHPSDSE-GELNIELTESYVDLGIKKVNwKKSKVN 527
Cdd:TIGR02168  235 EELREELEELQEELKEAEEELEELTAELQELEEKL----EELRLEVSELEEEiEELQKELYALANEISRLEQQ-KQILRE 309
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  528 SIVQQEDPNEELSkdEFILKLKAEVQRLLGSNSMKRRLVSQLQNDLKDCHKKIEDLHQVKRDEKSIEVEtktdtsekPKN 607
Cdd:TIGR02168  310 RLANLERQLEELE--AQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEE--------LEE 379
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  608 QLWLESSTSDIVRDDILLLKNEIQVLQQQNQELKETEEKLRNTNQDLCNQMRQMVQDFDHDKREAVDRCERTYQQHHEAM 687
Cdd:TIGR02168  380 QLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERL 459
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  688 ktQIRESLLAKHALEKQQLFEAYERTHLQLRSELDKVNKEMTAVQECYLEVCREKDHlestlRKTTEKEQQTQEKLLEER 767
Cdd:TIGR02168  460 --EEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKN-----QSGLSGILGVLSELISVD 532
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  768 EEYVSKLQVELEKKYQDTLMMEKSKWLKDQETDIKQQVENEVILAKAHWDKEQKEIKEKLIQQLEKEWQSKLDQTIK--- 844
Cdd:TIGR02168  533 EGYEAAIEAALGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKfdp 612
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  845 -----------------------AMKKKTSDRGS----QTDQVTTSDVISK-----------KEMAIMIEEQKCIIQQHL 886
Cdd:TIGR02168  613 klrkalsyllggvlvvddldnalELAKKLRPGYRivtlDGDLVRPGGVITGgsaktnssileRRREIEELEEKIEELEEK 692
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  887 EQEKDIAIKGAMKKL---------------EIELELKHCENIAKQVEIAVQNARQRWLGELPELAEYQALVRAEQKKWE- 950
Cdd:TIGR02168  693 IAELEKALAELRKELeeleeeleqlrkeleELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEe 772
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  951 --------EQHEVSVNKRISfAVSEAKEKWKSELENMKKNIlpgTELEEKIHSLQRELE-LKNEEVPVVIRAELAKARSE 1021
Cdd:TIGR02168  773 aeeelaeaEAEIEELEAQIE-QLKEELKALREALDELRAEL---TLLNEEAANLRERLEsLERRIAATERRLEDLEEQIE 848
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050 1022 WNKEKQEEIRRIQEQNEQDYRQFLDDH------RNKINEVLAAAKEDFMKQKTEL---------LLQKETELQTCLDQSR 1086
Cdd:TIGR02168  849 ELSEDIESLAAEIEELEELIEELESELeallneRASLEEALALLRSELEELSEELreleskrseLRRELEELREKLAQLE 928
                          810       820       830       840
                   ....*....|....*....|....*....|....*....|....*
gi 1622953050 1087 REWTMQEAKRIQLeiyqyeEDILTVLGVLLRDTQKEHVSDFEDKQ 1131
Cdd:TIGR02168  929 LRLEGLEVRIDNL------QERLSEEYSLTLEEAEALENKIEDDE 967
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
802-1107 6.05e-05

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 47.81  E-value: 6.05e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  802 KQQVENEVILAKAHWDKEQKEIKEKLIQQ-LEKEWQSKLDQTIKAMKKKTSDRGSQTDQVTTSDVISKKEMAIMIEEQKC 880
Cdd:pfam17380  263 QTMTENEFLNQLLHIVQHQKAVSERQQQEkFEKMEQERLRQEKEEKAREVERRRKLEEAEKARQAEMDRQAAIYAEQERM 342
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  881 IIQQHLEQEKdiaIKGAMKKLEIELelkhceniAKQVEIAVQNARQRWLGELP--------------ELAEYQALVRAEQ 946
Cdd:pfam17380  343 AMERERELER---IRQEERKRELER--------IRQEEIAMEISRMRELERLQmerqqknervrqelEAARKVKILEEER 411
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  947 KKWEEQHEVSVNKrISFAVSEAKEKWKSELENMKKNILPGTELEEKIHSLQRELELKNEEVPVVIRAELAKARSEwNKEK 1026
Cdd:pfam17380  412 QRKIQQQKVEMEQ-IRAEQEEARQREVRRLEEERAREMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRD-RKRA 489
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050 1027 QEEIRRIQEQNEQDYRQFLDDHRNKiNEVLAAAKEDFMKQKTELLLQKETElqtclDQSRREWTMQEAKRIQLEIYQYEE 1106
Cdd:pfam17380  490 EEQRRKILEKELEERKQAMIEEERK-RKLLEKEMEERQKAIYEEERRREAE-----EERRKQQEMEERRRIQEQMRKATE 563

                   .
gi 1622953050 1107 D 1107
Cdd:pfam17380  564 E 564
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
641-949 1.11e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 47.24  E-value: 1.11e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  641 KETEEKLRNTNQ------DLCNQMRQMVqdfDHDKREA------------VDRCE--------RTYQQHHEAMKTQIRES 694
Cdd:COG1196    175 EEAERKLEATEEnlerleDILGELERQL---EPLERQAekaeryrelkeeLKELEaellllklRELEAELEELEAELEEL 251
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  695 LLAKHALEKQQlfEAYERTHLQLRSELDKVNKEMTAVQECYLEVCREKDHLESTLRKTTEKEQQTQEKLLEEREEyVSKL 774
Cdd:COG1196    252 EAELEELEAEL--AELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEE-LAEL 328
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  775 QVELEKKYQdtlmmEKSKWLKDQETDIKQQVENEVILAKAhwdKEQKEIKEKLIQQLEKEWQSKLDQTIKAMKKKTSDRg 854
Cdd:COG1196    329 EEELEELEE-----ELEELEEELEEAEEELEEAEAELAEA---EEALLEAEAELAEAEEELEELAEELLEALRAAAELA- 399
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  855 SQTDQVTTSDVISKKEMAIMIEEQKCIIQQHLEQEKDIAIKGAMKKLEIELELKHCENIAKQVEIAVQNARQRWLGELPE 934
Cdd:COG1196    400 AQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAAL 479
                          330
                   ....*....|....*
gi 1622953050  935 LAEYQALVRAEQKKW 949
Cdd:COG1196    480 AELLEELAEAAARLL 494
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
310-847 2.42e-04

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 46.26  E-value: 2.42e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  310 IKALETQIQALKVN----EEQMIKKSRTTEMALESLKQQlvdlhHSESLQRAREQHESVVMGLTKK---YEEQVLSLQKN 382
Cdd:pfam15921  226 LRELDTEISYLKGRifpvEDQLEALKSESQNKIELLLQQ-----HQDRIEQLISEHEVEITGLTEKassARSQANSIQSQ 300
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  383 LDATVTALKEQEDICSRlkdHVKQLERNQEAIKLEKTEIINRLTRSLEESQKQCahLLQSGSVQEVAQLQFQLQQAqkah 462
Cdd:pfam15921  301 LEIIQEQARNQNSMYMR---QLSDLESTVSQLRSELREAKRMYEDKIEELEKQL--VLANSELTEARTERDQFSQE---- 371
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  463 tmSENMNKALQEELTELKDEislyesaaklgihpsdsEGELNIELTESyvdlgikKVNWKKSKVNSIV------QQEDPN 536
Cdd:pfam15921  372 --SGNLDDQLQKLLADLHKR-----------------EKELSLEKEQN-------KRLWDRDTGNSITidhlrrELDDRN 425
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  537 EELSKDEFILK-LKAEVQ--------RLLGSNSMKRR---LVSQLQNDLKDCHKKIEDLHQVKRDEKSIEVETKTDTSEK 604
Cdd:pfam15921  426 MEVQRLEALLKaMKSECQgqmerqmaAIQGKNESLEKvssLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASL 505
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  605 PKNQLWLESSTSDIVRddillLKNEIQVLQQQNQELKETEEKLRNTnQDLCNQMR-QMVQDfdhdkreavDRCERTYQQH 683
Cdd:pfam15921  506 QEKERAIEATNAEITK-----LRSRVDLKLQELQHLKNEGDHLRNV-QTECEALKlQMAEK---------DKVIEILRQQ 570
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  684 HEAMktqiresllakhalekQQLFEAYERTHLQLRSELDKVNKEMTAVQECYLEVCREKDHLESTLRKTTEKEQQTQEKL 763
Cdd:pfam15921  571 IENM----------------TQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEFKILKDKKDAKIRELEARVSDLELEK 634
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  764 LEEREEYVSKLQ-VELEKKYQDTLMMEkskwLKDQETDIKQQVENEVILAKAHWDK--EQKEIKEKLIQQLeKEWQSKLD 840
Cdd:pfam15921  635 VKLVNAGSERLRaVKDIKQERDQLLNE----VKTSRNELNSLSEDYEVLKRNFRNKseEMETTTNKLKMQL-KSAQSELE 709

                   ....*..
gi 1622953050  841 QTIKAMK 847
Cdd:pfam15921  710 QTRNTLK 716
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
236-1096 2.55e-04

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 46.19  E-value: 2.55e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  236 ENMQIIQLQVLNKAKERQLE-NLVEKLNESECQIR--------YLNHQLVIIKDEKDGLTlSLRESQKLFQNGKEREIQL 306
Cdd:TIGR00606  189 ETLRQVRQTQGQKVQEHQMElKYLKQYKEKACEIRdqitskeaQLESSREIVKSYENELD-PLKNRLKEIEHNLSKIMKL 267
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  307 EAQIKALE-TQIQALKVNEEQMIKKSRTTEMALESLKqQLVDLHHSESLQRARE-----------QHESVVMGLTK---K 371
Cdd:TIGR00606  268 DNEIKALKsRKKQMEKDNSELELKMEKVFQGTDEQLN-DLYHNHQRTVREKERElvdcqreleklNKERRLLNQEKtelL 346
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  372 YEEQVLSLQKNLDATVTALKEQEDICSRLKDHVKQLERN---QEAIKLEKTEIINRLTRSLEESQKQCAHLLQSGSVQEV 448
Cdd:TIGR00606  347 VEQGRLQLQADRHQEHIRARDSLIQSLATRLELDGFERGpfsERQIKNFHTLVIERQEDEAKTAAQLCADLQSKERLKQE 426
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  449 AQLQFQLQQAQKAHTMsENMNKALQEELTELKDEISLYESAAKlgihPSDSEGELNIELTESYVDLGIKkvnwKKSKVNS 528
Cdd:TIGR00606  427 QADEIRDEKKGLGRTI-ELKKEILEKKQEELKFVIKELQQLEG----SSDRILELDQELRKAERELSKA----EKNSLTE 497
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  529 IVQQEDPNEELSKDEFILKLKAEVQRLLGSNSMKRRLvSQLQNDLKDCHKKIEDLHQVKRDEKSIEVETKTDTSEKPKNQ 608
Cdd:TIGR00606  498 TLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTR-TQMEMLTKDKMDKDEQIRKIKSRHSDELTSLLGYFPNKKQLE 576
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  609 LWLESSTSDI--VRDDILLLKNEIQVLQQQNQELKETEEKLRNTNQDLCNQMRQMV--QDFDHDKREAVDRCERTYQQHH 684
Cdd:TIGR00606  577 DWLHSKSKEInqTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLFDVCgsQDEESDLERLKEEIEKSSKQRA 656
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  685 E-AMKTQIRESLLAKHALEKQQLFEAYERThLQLRSELDKVNKEMTAVQECYLEVCREKDHLESTLRKTTE--------- 754
Cdd:TIGR00606  657 MlAGATAVYSQFITQLTDENQSCCPVCQRV-FQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDemlglapgr 735
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  755 -KEQQTQEKLLEEREEYVSKLQVELEKKYQDTLMMEKSKWLKDQETDIKQQVENEVILAKaHWDKEQKEIKEKLIQQLEK 833
Cdd:TIGR00606  736 qSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAKVCLTDVTIME-RFQMELKDVERKIAQQAAK 814
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  834 EWQSKLDQTIKAMKKKTSDRGSQTDQVTTSDVISKKemaiMIEEQKCIIqQHLEQEKDiaiKGAMKKLEIELELKHCENI 913
Cdd:TIGR00606  815 LQGSDLDRTVQQVNQEKQEKQHELDTVVSKIELNRK----LIQDQQEQI-QHLKSKTN---ELKSEKLQIGTNLQRRQQF 886
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  914 AKQVEIAVQNArQRWLGELPELAEYQALVRAEQKKWEEQHEVSVNKRisfavSEAKEKWKSELENMKKNIlpgteleEKI 993
Cdd:TIGR00606  887 EEQLVELSTEV-QSLIREIKDAKEQDSPLETFLEKDQQEKEELISSK-----ETSNKKAQDKVNDIKEKV-------KNI 953
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  994 HSLQRELELKNEEvpvviraelakARSEWNKEKQEEIRRIQEQNEQDyrqflDDHRNKINEVLAAAKEDFMKQKtelllQ 1073
Cdd:TIGR00606  954 HGYMKDIENKIQD-----------GKDDYLKQKETELNTVNAQLEEC-----EKHQEKINEDMRLMRQDIDTQK-----I 1012
                          890       900
                   ....*....|....*....|...
gi 1622953050 1074 KETELQTCLDQSRREWTMQEAKR 1096
Cdd:TIGR00606 1013 QERWLQDNLTLRKRENELKEVEE 1035
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
470-774 3.33e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 45.68  E-value: 3.33e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  470 KALQEELTELKDEIS-LYESAAKLgihpsdsEGELNIELTESYVDLGIKKVNWKKSKVNSIVQQedpneelskdefILKL 548
Cdd:COG4913    613 AALEAELAELEEELAeAEERLEAL-------EAELDALQERREALQRLAEYSWDEIDVASAERE------------IAEL 673
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  549 KAEVQRLLGSNSMKRRL---VSQLQNDLKDCHKKIEDL--------HQVKRDEKSIEvETKTDTSEKPKNQLWLESSTSD 617
Cdd:COG4913    674 EAELERLDASSDDLAALeeqLEELEAELEELEEELDELkgeigrleKELEQAEEELD-ELQDRLEAAEDLARLELRALLE 752
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  618 IVRDDILLLKNEIQVLQQQNQELKETEEKLRNTNQDLCNQMRQMVQDFDHDKREAVDRCE--RTYQQHHEamktQIRESL 695
Cdd:COG4913    753 ERFAAALGDAVERELRENLEERIDALRARLNRAEEELERAMRAFNREWPAETADLDADLEslPEYLALLD----RLEEDG 828
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  696 LAKHaleKQQLFEA------YERTHL--QLRSE-------LDKVNKEMTAV---QECYLEVCREKDHLEST------LRK 751
Cdd:COG4913    829 LPEY---EERFKELlnensiEFVADLlsKLRRAireikerIDPLNDSLKRIpfgPGRYLRLEARPRPDPEVrefrqeLRA 905
                          330       340
                   ....*....|....*....|...
gi 1622953050  752 TTEKEQQTQEKLLEEREEYVSKL 774
Cdd:COG4913    906 VTSGASLFDEELSEARFAALKRL 928
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
639-1300 3.64e-04

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 45.48  E-value: 3.64e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  639 ELKETEEKLRNtNQDLCNQMRQMVQDFDHDKREAVDRCERTYQQHheamKTQIRESLLAKH-----------ALEKQQLF 707
Cdd:pfam05483  100 ELKQKENKLQE-NRKIIEAQRKAIQELQFENEKVSLKLEEEIQEN----KDLIKENNATRHlcnllketcarSAEKTKKY 174
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  708 EAYERTHLQLRSELDK-VNKEMTAVQECYLEVCREKDHLESTLRKTTEKEQQTQE---KLLEEREEYVSKLQV---ELEK 780
Cdd:pfam05483  175 EYEREETRQVYMDLNNnIEKMILAFEELRVQAENARLEMHFKLKEDHEKIQHLEEeykKEINDKEKQVSLLLIqitEKEN 254
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  781 KYQD-TLMMEKSKWLKDQ-ETDIKQQVEN--EVILAKAHWDKEQKEIKEKLIQQL--EKEWQSKLDQTIKAMKKKTSDRG 854
Cdd:pfam05483  255 KMKDlTFLLEESRDKANQlEEKTKLQDENlkELIEKKDHLTKELEDIKMSLQRSMstQKALEEDLQIATKTICQLTEEKE 334
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  855 SQTDQ-----VTTSDVISKKEMAI-MIEEQKCIIQQHLEQEKDiaikgAMKKLEIELELKHCEniaKQVEIAVQNARQRW 928
Cdd:pfam05483  335 AQMEElnkakAAHSFVVTEFEATTcSLEELLRTEQQRLEKNED-----QLKIITMELQKKSSE---LEEMTKFKNNKEVE 406
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  929 LGELPE-LAEYQALVRAEQKKWEEQHEVSVNKRISFAVSEAKEKWKSELENMKKNILPGTELEEK-IHSLQRELE---LK 1003
Cdd:pfam05483  407 LEELKKiLAEDEKLLDEKKQFEKIAEELKGKEQELIFLLQAREKEIHDLEIQLTAIKTSEEHYLKeVEDLKTELEkekLK 486
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050 1004 NEEVPvviraelakarSEWNKEKQEEIRRIQEQNeqDYRQFLDDHRNKINEvlAAAKEDFMKQKTELLLQKETELQTCLD 1083
Cdd:pfam05483  487 NIELT-----------AHCDKLLLENKELTQEAS--DMTLELKKHQEDIIN--CKKQEERMLKQIENLEEKEMNLRDELE 551
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050 1084 QSRREWtMQEAKRIQLEIYQYEEDILTVLGVLLRDTQKEHVSDFEDKQLLEIMSTCSskwmsvQYFEKLKGcIQKAFQDT 1163
Cdd:pfam05483  552 SVREEF-IQKGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKN------KNIEELHQ-ENKALKKK 623
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050 1164 LPLLVENADPQWEKRNMAELSKDSASRSTGqgvpgpaaghhaqplalqetEAEADKKKILEIKDLCCGHCFQELEKAK-- 1241
Cdd:pfam05483  624 GSAENKQLNAYEIKVNKLELELASAKQKFE--------------------EIIDNYQKEIEDKKISEEKLLEEVEKAKai 683
                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050 1242 -QECEDLKGKLEKCCrhlQHLERKHKAVVEKIGEENNKVIEELIEENNDMKNKLEELRTL 1300
Cdd:pfam05483  684 aDEAVKLQKEIDKRC---QHKIAEMVALMEKHKHQYDKIIEERDSELGLYKNKEQEQSSA 740
PRK13460 PRK13460
F0F1 ATP synthase subunit B; Provisional
1025-1132 3.79e-04

F0F1 ATP synthase subunit B; Provisional


Pssm-ID: 139585 [Multi-domain]  Cd Length: 173  Bit Score: 43.09  E-value: 3.79e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050 1025 EKQEEIRRIQEQNEQDYRQFLDDHRNKINEVLAAAKEDFMKQKTELLLQKETELQTCLDQSRREWTMQEAKRI-QLEIYQ 1103
Cdd:PRK13460    57 NKASELRLEAEALLKDYEARLNSAKDEANAIVAEAKSDALKLKNKLLEETNNEVKAQKDQAVKEIELAKGKALsQLQNQI 136
                           90       100
                   ....*....|....*....|....*....
gi 1622953050 1104 YEEDILTVLGVLLRDTQKEHVSDFEDKQL 1132
Cdd:PRK13460   137 VEMTITIASKVLEKQLKKEDYKAFIETEL 165
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
625-1134 4.24e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 45.31  E-value: 4.24e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  625 LLKNEIQVLQQQNQELKETEEKLRNTNQDLCNQMRQMVQDFDHDKREAVDRCERTYQQHHEamktqiRESLLAKHALEKQ 704
Cdd:COG1196    264 ELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEE------LAELEEELEELEE 337
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  705 QLfeayerthLQLRSELDKVNKEMTAVQEcylevcrEKDHLESTLRKTTEKEQQTQEKLLEEREEYVSKLQVELE-KKYQ 783
Cdd:COG1196    338 EL--------EELEEELEEAEEELEEAEA-------ELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAElAAQL 402
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  784 DTLMMEKSKWLKDQETDIKQQVENEVILAKAhwdkEQKEIKEKLIQQLEKEWQSKLDQTIKAMKKKTSDRGSQTDQVTTS 863
Cdd:COG1196    403 EELEEAEEALLERLERLEEELEELEEALAEL----EEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAA 478
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  864 DVISKKEMAIMIEEQKCIIQQHLEQEKDIAIKGAMKKLEIELELKHCENIAKQVEIAVQNARQRWLGELpeLAEYQALVR 943
Cdd:COG1196    479 LAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAA--LQNIVVEDD 556
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  944 AEQKKWEEQHEVSVNKRISF------AVSEAKEKWKSELENMKKNILPGTELEEKIHSLQRELELKNEEVPVVIRAELAK 1017
Cdd:COG1196    557 EVAAAAIEYLKAAKAGRATFlpldkiRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAAL 636
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050 1018 ARSEwnKEKQEEIRRIQEQNEQDYRQFLDDHRNKINEVLAAAKEDFMKQKTELLLQKETELQTCLDQSRREWTMQEAKRI 1097
Cdd:COG1196    637 RRAV--TLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEE 714
                          490       500       510
                   ....*....|....*....|....*....|....*..
gi 1622953050 1098 QLEIYQYEEDILTVLGVLLRDTQKEHVSDFEDKQLLE 1134
Cdd:COG1196    715 ERLEEELEEEALEEQLEAEREELLEELLEEEELLEEE 751
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
239-907 4.71e-04

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 45.42  E-value: 4.71e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  239 QIIQLQVLNKAKERQLENLVEKLNESECQIRYLNHQL---------VIIKDEKdgLTLSLRESQKLFQNgkereiqleAQ 309
Cdd:TIGR00606  427 QADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKELqqlegssdrILELDQE--LRKAERELSKAEKN---------SL 495
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  310 IKALETQIQALKVNEEQMIKKSRTTEMALESLKQQLVDLHHSESLQRAREQHESVVMGLTKKYEEQVLSL------QKNL 383
Cdd:TIGR00606  496 TETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLlgyfpnKKQL 575
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  384 DATVTALKEQEDIcsrLKDHVKQLERNQEAIKLEKTEIINRLTRSLEESQKQCAHLLQSGSVQEvaqlqfqlqQAQKAHT 463
Cdd:TIGR00606  576 EDWLHSKSKEINQ---TRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLFDVCGSQD---------EESDLER 643
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  464 MSENMNKAlQEELTELKDEISLYESAAKLGIHPSDSEGELNIELTESYvdlgiKKVNWKKSKVNSIVQQEdPNEELSKDE 543
Cdd:TIGR00606  644 LKEEIEKS-SKQRAMLAGATAVYSQFITQLTDENQSCCPVCQRVFQTE-----AELQEFISDLQSKLRLA-PDKLKSTES 716
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  544 FILKLKAEVQRLLGSNSMKRRLVSQLQNDLKDCHKKIEDLHQVKRDEKSievetKTDTSEKPKNQLWLESSTSDIVRDDI 623
Cdd:TIGR00606  717 ELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKN-----DIEEQETLLGTIMPEEESAKVCLTDV 791
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  624 LLLKNEIQVLQQQNQELKETEEKLRNTNQDLC-NQMRQMVQDFDHDKREAVDRCERTYQQHHEAMK-TQIRESLLAKHAL 701
Cdd:TIGR00606  792 TIMERFQMELKDVERKIAQQAAKLQGSDLDRTvQQVNQEKQEKQHELDTVVSKIELNRKLIQDQQEqIQHLKSKTNELKS 871
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  702 EKQQLFEAYERTHlQLRSELDKVNKEmtaVQECYLEVcrekdhleSTLRKTTEKEQQTQEKLLEEREEYVSKLQVElEKK 781
Cdd:TIGR00606  872 EKLQIGTNLQRRQ-QFEEQLVELSTE---VQSLIREI--------KDAKEQDSPLETFLEKDQQEKEELISSKETS-NKK 938
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  782 YQDTLMMEKSKWlkDQETDIKQQVENEVILAKAHWDKEQKEIKEKLIQQLEkEWQSKLDQTIKAMKKKTSDRGSQTDQVT 861
Cdd:TIGR00606  939 AQDKVNDIKEKV--KNIHGYMKDIENKIQDGKDDYLKQKETELNTVNAQLE-ECEKHQEKINEDMRLMRQDIDTQKIQER 1015
                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|
gi 1622953050  862 -TSDVISKKEMAIMIEEQKCIIQQHLEQEKDIAI---KGAMKKLEIELEL 907
Cdd:TIGR00606 1016 wLQDNLTLRKRENELKEVEEELKQHLKEMGQMQVlqmKQEHQKLEENIDL 1065
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
300-951 4.82e-04

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 44.96  E-value: 4.82e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  300 KEREIQLEAQIKALETQIQALKVNEEQMIKKSRTTEMALESLKQQLVdlhhsESLQRAREQHESVVMGLTKkyEEQVLSL 379
Cdd:TIGR00618  186 FAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLR-----EALQQTQQSHAYLTQKREA--QEEQLKK 258
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  380 QKNLDATVTALKEQEDICSRLKDHVKQLERNQEAIKL----------------EKTEIINRLTRSLEESQKQCAHLLQSG 443
Cdd:TIGR00618  259 QQLLKQLRARIEELRAQEAVLEETQERINRARKAAPLaahikavtqieqqaqrIHTELQSKMRSRAKLLMKRAAHVKQQS 338
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  444 SVQEVAQLQFQ------------------LQQAQKAHTMSENMnKALQEELTELKDEISLyeSAAKLGIhpSDSEGELNI 505
Cdd:TIGR00618  339 SIEEQRRLLQTlhsqeihirdahevatsiREISCQQHTLTQHI-HTLQQQKTTLTQKLQS--LCKELDI--LQREQATID 413
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  506 ELTESYVDLGIKKVNWKKSKVNSIVQQEDPNEELSKDEFILKLKaevQRLLGSNSMKRRLVSQLQNDLKDCHKKIEDLHQ 585
Cdd:TIGR00618  414 TRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLE---KIHLQESAQSLKEREQQLQTKEQIHLQETRKKA 490
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  586 V--KRDEKSIEVETKTDTSEKPKNQLWLESSTSDIVRDDILLLKNEIQVLQQQNQELKETEEKLRNTNQDLCNQMRQMVQ 663
Cdd:TIGR00618  491 VvlARLLELQEEPCPLCGSCIHPNPARQDIDNPGPLTRRMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQ 570
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  664 DFdhdkrEAVDRCERTYQQHHEAMK--TQIRESLLAKHALEKQQLFEAYERTHLQLRSELDKVNKEMTAvQECYLEVCRE 741
Cdd:TIGR00618  571 SF-----SILTQCDNRSKEDIPNLQniTVRLQDLTEKLSEAEDMLACEQHALLRKLQPEQDLQDVRLHL-QQCSQELALK 644
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  742 KDHLEstlrkttekeqQTQEKLLEEREEYVSKLQVELEKKY--QDTLMMEKSKWLKDQETDIKQQVENEVILAKAHWDKE 819
Cdd:TIGR00618  645 LTALH-----------ALQLTLTQERVREHALSIRVLPKELlaSRQLALQKMQSEKEQLTYWKEMLAQCQTLLRELETHI 713
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  820 QKEIKE-KLIQQLEKEWQSKLDQTIKAMKKKTSDRGSQTDQVTTSDVI--SKKEMAIMIEEQKCIIQQHLEQEKDIAIKG 896
Cdd:TIGR00618  714 EEYDREfNEIENASSSLGSDLAAREDALNQSLKELMHQARTVLKARTEahFNNNEEVTAALQTGAELSHLAAEIQFFNRL 793
                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1622953050  897 --------AMKKLEIELELKHCENIAKQVEIAVQNARQRWLGELPELAEYQALVRAEQKKWEE 951
Cdd:TIGR00618  794 reedthllKTLEAEIGQEIPSDEDILNLQCETLVQEEEQFLSRLEEKSATLGEITHQLLKYEE 856
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
670-1036 5.27e-04

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 45.21  E-value: 5.27e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  670 REAVDRCERTYQQHHEAMKTQIRESLLAKHALEKQQLFEAYERTHL------------QLRSELDKVNKEMTAVQECYLE 737
Cdd:pfam12128  603 RERLDKAEEALQSAREKQAAAEEQLVQANGELEKASREETFARTALknarldlrrlfdEKQSEKDKKNKALAERKDSANE 682
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  738 VCREKDH-LESTLRKTTEKEQQTQEKLLEEREEYVSKLQVELEKKyqdtlmmekskwlKDQETDIKQQVENEVILAKAHW 816
Cdd:pfam12128  683 RLNSLEAqLKQLDKKHQAWLEEQKEQKREARTEKQAYWQVVEGAL-------------DAQLALLKAAIAARRSGAKAEL 749
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  817 DKEQKEIKEKLIQQ-LEKEWQSKLDQTIKAMKKKTSDRGSQTDQVTTSDV-------ISKKEMAIMIEEqkcIIQQHLEQ 888
Cdd:pfam12128  750 KALETWYKRDLASLgVDPDVIAKLKREIRTLERKIERIAVRRQEVLRYFDwyqetwlQRRPRLATQLSN---IERAISEL 826
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  889 EKDIAIKGAMKKLEI-ELELKHCENIAKQVEIAVQnarqrwLGELPELAEYQALVRAEQKKWEEQHEVSVNKRisfAVSE 967
Cdd:pfam12128  827 QQQLARLIADTKLRRaKLEMERKASEKQQVRLSEN------LRGLRCEMSKLATLKEDANSEQAQGSIGERLA---QLED 897
                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1622953050  968 AKEKWKSELENMKKNI---------LPGTELEEKIHSLQREL-ELKNEEVPVVIRAELAKARSEWNKEKQEEIRRIQEQ 1036
Cdd:pfam12128  898 LKLKRDYLSESVKKYVehfknviadHSGSGLAETWESLREEDhYQNDKGIRLLDYRKLVPYLEQWFDVRVPQSIMVLRE 976
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
225-750 9.01e-04

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 44.33  E-value: 9.01e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  225 QQFLGANENSAENMQIIQLQVLNKAKERqlENLVEKLNESECqirylNHQLVIIKDEKDGLTLslresQKLFQNGKEREI 304
Cdd:pfam05483  306 QRSMSTQKALEEDLQIATKTICQLTEEK--EAQMEELNKAKA-----AHSFVVTEFEATTCSL-----EELLRTEQQRLE 373
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  305 QLEAQIKALETQIQALKVNEEQMIKKSRTTEMALESLKQQLVDlhhSESLQRAREQHESVVMGLTKKYEEQVLSLQK--- 381
Cdd:pfam05483  374 KNEDQLKIITMELQKKSSELEEMTKFKNNKEVELEELKKILAE---DEKLLDEKKQFEKIAEELKGKEQELIFLLQArek 450
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  382 ---NLDATVTALKEQEDICSRlkdHVKQLERNQEAIKLEKTEIINRLTRSLEESQKqcahLLQSGS--VQEVAQLQFQLQ 456
Cdd:pfam05483  451 eihDLEIQLTAIKTSEEHYLK---EVEDLKTELEKEKLKNIELTAHCDKLLLENKE----LTQEASdmTLELKKHQEDII 523
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  457 QAQKAHTMSENMNKALQEELTELKDEIslyesaaklgihpsdsegelnieltESYVDLGIKKVNWKKSKVnsivqqeDPN 536
Cdd:pfam05483  524 NCKKQEERMLKQIENLEEKEMNLRDEL-------------------------ESVREEFIQKGDEVKCKL-------DKS 571
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  537 EELSKDEFILKLKAEVQRLLGSNSmkrrlVSQLQNDLKDCHKKIEDLHQVKR--DEKSIEVETKTDTSEKPKNQLWLE-S 613
Cdd:pfam05483  572 EENARSIEYEVLKKEKQMKILENK-----CNNLKKQIENKNKNIEELHQENKalKKKGSAENKQLNAYEIKVNKLELElA 646
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  614 STSDIVRDDILLLKNEIQVLQQQNQELKETEEKLRNTNQDLCNQMRQMVQDFDHDKREAVDRCERTYQQHHEAMKTQIRE 693
Cdd:pfam05483  647 SAKQKFEEIIDNYQKEIEDKKISEEKLLEEVEKAKAIADEAVKLQKEIDKRCQHKIAEMVALMEKHKHQYDKIIEERDSE 726
                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1622953050  694 SLLAKHALEKQQLFEAYERTHL-QLRSELDKVNKEMTAVQECYLEVCREKDHLESTLR 750
Cdd:pfam05483  727 LGLYKNKEQEQSSAKAALEIELsNIKAELLSLKKQLEIEKEEKEKLKMEAKENTAILK 784
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
301-784 1.05e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 44.14  E-value: 1.05e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  301 EREIQLEAQIKALETQIQALKVNEEQmiKKSRTTEMALESLKQQLVDLHHS-ESLQRAREQHESVVMGLTKKYEE----Q 375
Cdd:COG4913    262 ERYAAARERLAELEYLRAALRLWFAQ--RRLELLEAELEELRAELARLEAElERLEARLDALREELDELEAQIRGnggdR 339
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  376 VLSLQKNLDATVTALKEQEDICSRLKDHVKQLErnqeaIKLEKTEiinrltRSLEESQKQCAHLLQSGSVQEvaqlqfql 455
Cdd:COG4913    340 LEQLEREIERLERELEERERRRARLEALLAALG-----LPLPASA------EEFAALRAEAAALLEALEEEL-------- 400
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  456 QQAQKAHTMSENMNKALQEELTELKDEISLYES----------------AAKLGIHPSDSE--GELnIELTESYVDlgik 517
Cdd:COG4913    401 EALEEALAEAEAALRDLRRELRELEAEIASLERrksniparllalrdalAEALGLDEAELPfvGEL-IEVRPEEER---- 475
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  518 kvnWKK--------------------SKVNSIVQQEDPNEELSKDEFILKLKAEVQRLLGSNSMKRRLVSQ-------LQ 570
Cdd:COG4913    476 ---WRGaiervlggfaltllvppehyAAALRWVNRLHLRGRLVYERVRTGLPDPERPRLDPDSLAGKLDFKphpfrawLE 552
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  571 NDLKD--CHKKIEDLHQVKRDEKSIEVE--TKTDTS--EKPKNQlwlesstsDIVRDDILLLKNE--IQVLQQQNQELKE 642
Cdd:COG4913    553 AELGRrfDYVCVDSPEELRRHPRAITRAgqVKGNGTrhEKDDRR--------RIRSRYVLGFDNRakLAALEAELAELEE 624
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  643 TEEKLRNTNQDLCNQMRQMVQdfdhdKREAVDRCE---------RTYQQHHEAMKTQIRESLLAKHALE--KQQLfEAYE 711
Cdd:COG4913    625 ELAEAEERLEALEAELDALQE-----RREALQRLAeyswdeidvASAEREIAELEAELERLDASSDDLAalEEQL-EELE 698
                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1622953050  712 RTHLQLRSELDKVNKEMTAVQECYLEVCREKDHLESTLRKTTEKEQQTQEKLLEER------EEYVSKLQVELEKKYQD 784
Cdd:COG4913    699 AELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERfaaalgDAVERELRENLEERIDA 777
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
244-441 1.14e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 43.85  E-value: 1.14e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  244 QVLNK-AKERQLENLVEKLNESECQIRYLNHQLVIIKDEKDGLTLSLRE--SQKLFQNGKEREIQLEAQIKALETQIQAL 320
Cdd:COG3206    152 AVANAlAEAYLEQNLELRREEARKALEFLEEQLPELRKELEEAEAALEEfrQKNGLVDLSEEAKLLLQQLSELESQLAEA 231
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  321 KVNEEQMIKKSRTTEMALESLKQQLVDLHHSESLQRAREQH---ESVVMGLTKKYEE---QVLSLQKNLDATVTALK-EQ 393
Cdd:COG3206    232 RAELAEAEARLAALRAQLGSGPDALPELLQSPVIQQLRAQLaelEAELAELSARYTPnhpDVIALRAQIAALRAQLQqEA 311
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1622953050  394 EDICSRLKDHVKQLERNQEAIKLEKTEI-------------INRLTRSLEESQKQCAHLLQ 441
Cdd:COG3206    312 QRILASLEAELEALQAREASLQAQLAQLearlaelpeleaeLRRLEREVEVARELYESLLQ 372
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
249-414 1.24e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 43.75  E-value: 1.24e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  249 AKERQLENLVEKLNESECQIRYLNHQLVIIKDEKDGLTLSLRE-SQKLFQNGKEREIQLEAQIKALETQIQALKVNEEQM 327
Cdd:COG4913    285 FAQRRLELLEAELEELRAELARLEAELERLEARLDALREELDElEAQIRGNGGDRLEQLEREIERLERELEERERRRARL 364
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  328 IKKSRTTEMALESLKQQLVDLHhsESLQRAREQHESVVMGLTKKYEEqvlslqknLDATVTALKEQEDicsRLKDHVKQL 407
Cdd:COG4913    365 EALLAALGLPLPASAEEFAALR--AEAAALLEALEEELEALEEALAE--------AEAALRDLRRELR---ELEAEIASL 431

                   ....*..
gi 1622953050  408 ERNQEAI 414
Cdd:COG4913    432 ERRKSNI 438
PRK12704 PRK12704
phosphodiesterase; Provisional
1210-1396 1.63e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 43.23  E-value: 1.63e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050 1210 LQETEAEAD---KKKILEIKDlccghcfqELEKAKQECE-DLKGKLEKccrhLQHLERK---HKAVVEKIGEENNKVIEE 1282
Cdd:PRK12704    44 LEEAKKEAEaikKEALLEAKE--------EIHKLRNEFEkELRERRNE----LQKLEKRllqKEENLDRKLELLEKREEE 111
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050 1283 LIEENNDMKNKLEELrtlcktpprslsagaientclpcsggalEELRGQYIKAVKKIKRDMLRYIQESKERAAEMVKAEV 1362
Cdd:PRK12704   112 LEKKEKELEQKQQEL----------------------------EKKEEELEELIEEQLQELERISGLTAEEAKEILLEKV 163
                          170       180       190
                   ....*....|....*....|....*....|....*
gi 1622953050 1363 LRE-RQETARKMRKYYliclqqilqDDGKEGAEKK 1396
Cdd:PRK12704   164 EEEaRHEAAVLIKEIE---------EEAKEEADKK 189
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
716-1001 1.69e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 43.52  E-value: 1.69e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  716 QLRSELDKVNKEMTAVQEcYLEVCREKDHLESTLR----KTTEKEQQTQEKLLEEREEYVSKLQVELEKKYQDtlMMEKS 791
Cdd:TIGR02169  195 EKRQQLERLRREREKAER-YQALLKEKREYEGYELlkekEALERQKEAIERQLASLEEELEKLTEEISELEKR--LEEIE 271
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  792 KWLKDQETDIKQQVENEVILAKAHWDKEQKEI---------KEKLIQQLEKEWQ------SKLDQTIKAMKKKTSDRGSQ 856
Cdd:TIGR02169  272 QLLEELNKKIKDLGEEEQLRVKEKIGELEAEIaslersiaeKERELEDAEERLAkleaeiDKLLAEIEELEREIEEERKR 351
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  857 TDQVTTSDVISKKEMAIMIEEqkciIQQhlEQEKDIAIKGAMKKLEIELE-LKHCENIAKQVEIAVQNARQRWLGELPEL 935
Cdd:TIGR02169  352 RDKLTEEYAELKEELEDLRAE----LEE--VDKEFAETRDELKDYREKLEkLKREINELKRELDRLQEELQRLSEELADL 425
                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1622953050  936 AEYQALVRAEQKKWEEQHEvSVNKRISFA------VSEAKEKWKSELENMKKNIlpgTELEEKIHSLQRELE 1001
Cdd:TIGR02169  426 NAAIAGIEAKINELEEEKE-DKALEIKKQewkleqLAADLSKYEQELYDLKEEY---DRVEKELSKLQRELA 493
PRK12704 PRK12704
phosphodiesterase; Provisional
700-849 1.78e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 42.84  E-value: 1.78e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  700 ALEKQQLFEAYERTHlQLRSELDKVNKEMT---AVQECYLEvcREKDHLESTLRKTTEKEQ--QTQEKLLEEREEYVSKL 774
Cdd:PRK12704    53 AIKKEALLEAKEEIH-KLRNEFEKELRERRnelQKLEKRLL--QKEENLDRKLELLEKREEelEKKEKELEQKQQELEKK 129
                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1622953050  775 QVELEKKYQdtlmmekskwlkdqetdiKQQVENEVIlakAHWDKEqkEIKEKLIQQLEKEWQSKLDQTIKAMKKK 849
Cdd:PRK12704   130 EEELEELIE------------------EQLQELERI---SGLTAE--EAKEILLEKVEEEARHEAAVLIKEIEEE 181
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
816-1088 1.83e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 43.37  E-value: 1.83e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  816 WD-KEQKEIKEKLIQQLEKEWQsKLDQTIKAMKKKTSDrgsqtdqvttsdviskkemaimIEEQKCIIQQHLE-QEKDIA 893
Cdd:COG4913    606 FDnRAKLAALEAELAELEEELA-EAEERLEALEAELDA----------------------LQERREALQRLAEySWDEID 662
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  894 IKGAMKKL-EIELELKHCEN-------IAKQVEiAVQNARQRWLGELPELAEYQALVRAEQKKWEEQHEvSVNKRISFAV 965
Cdd:COG4913    663 VASAEREIaELEAELERLDAssddlaaLEEQLE-ELEAELEELEEELDELKGEIGRLEKELEQAEEELD-ELQDRLEAAE 740
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  966 SEAKEKWKSELENMKKNILPGTELEEKIHSLQRELELKNEEVpVVIRAELAKARSEWNKEKQEEIRRIQEQNEqDYRQFL 1045
Cdd:COG4913    741 DLARLELRALLEERFAAALGDAVERELRENLEERIDALRARL-NRAEEELERAMRAFNREWPAETADLDADLE-SLPEYL 818
                          250       260       270       280
                   ....*....|....*....|....*....|....*....|...
gi 1622953050 1046 DDHRNKINEVLAAAKEDFMKQKTELLLQKETELQTCLDQSRRE 1088
Cdd:COG4913    819 ALLDRLEEDGLPEYEERFKELLNENSIEFVADLLSKLRRAIRE 861
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
239-852 1.95e-03

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 43.09  E-value: 1.95e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  239 QIIQLQVLNKAKERQLENLVEKLNESECQIRYLNHQLVIIKDEKDGLTLSLRESQKLFQNGKEREIQLEAQIKALETQIQ 318
Cdd:TIGR04523  219 QISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEIS 298
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  319 ALKVNEEQmikksrttemaleslkqqlvdlhhseslqrareqhesvvmGLTKKYEEQVLSLQKNLDATVTALKEQEDICS 398
Cdd:TIGR04523  299 DLNNQKEQ----------------------------------------DWNKELKSELKNQEKKLEEIQNQISQNNKIIS 338
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  399 RLKDHVKQLERNQEAIKLEKTEIinrlTRSLEESQKQCAHLlqsgsvqevaqlqfqlqqaqkahtmsENMNKALQEELTE 478
Cdd:TIGR04523  339 QLNEQISQLKKELTNSESENSEK----QRELEEKQNEIEKL--------------------------KKENQSYKQEIKN 388
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  479 LKDEISlyesaaklgihpsdsegELNIELTEsyvdlgIKKVNwkKSKVNSIVQQEDPNEELSKD-----EFILKLKAEVQ 553
Cdd:TIGR04523  389 LESQIN-----------------DLESKIQN------QEKLN--QQKDEQIKKLQQEKELLEKEierlkETIIKNNSEIK 443
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  554 RLLGSNSMKRRLVSQLQNDLKDCHKKIEDLhqvkrdekSIEVETKTDTSEKPKNQLWLESSTSDIVRDDILLLKNEIQVL 633
Cdd:TIGR04523  444 DLTNQDSVKELIIKNLDNTRESLETQLKVL--------SRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDL 515
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  634 QQQNQELKETEEKLRNTNQDLCNQMRQMVQDFDHD----KREAVDRCERTYQQHHEAMKtQIRESLLAKHAlEKQQLFEA 709
Cdd:TIGR04523  516 TKKISSLKEKIEKLESEKKEKESKISDLEDELNKDdfelKKENLEKEIDEKNKEIEELK-QTQKSLKKKQE-EKQELIDQ 593
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  710 YERTHLQLRSEL-------DKVNKEMTAVQECYLEVCREKDHLESTLRKTTEKEQQTQEKLLEERE---EYVSKLQVELE 779
Cdd:TIGR04523  594 KEKEKKDLIKEIeekekkiSSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKEIRNkwpEIIKKIKESKT 673
                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1622953050  780 KKYQDTLMMEksKWLKDQETDIKQQV-----ENEVILAKAHWDKEQKEIKEklIQQLEKEwqskLDQTIKAMKKKTSD 852
Cdd:TIGR04523  674 KIDDIIELMK--DWLKELSLHYKKYItrmirIKDLPKLEEKYKEIEKELKK--LDEFSKE----LENIIKNFNKKFDD 743
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
347-1069 2.35e-03

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 42.79  E-value: 2.35e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  347 DLHHSESLQRAReqheSVVMGLTKKYEEQVLSLQKNLDATVTALKEQEDICSRLKDHVKQLERNQEAIKLEKTEIINRLT 426
Cdd:pfam05483   69 DFENSEGLSRLY----SKLYKEAEKIKKWKVSIEAELKQKENKLQENRKIIEAQRKAIQELQFENEKVSLKLEEEIQENK 144
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  427 RSLEESQ--KQCAHLLQSGSVQEVAQLQFQLQQAQKAHTMSENMNKALQEELTELkDEISLYESAAKLGIHPSDSEGELN 504
Cdd:pfam05483  145 DLIKENNatRHLCNLLKETCARSAEKTKKYEYEREETRQVYMDLNNNIEKMILAF-EELRVQAENARLEMHFKLKEDHEK 223
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  505 IE-LTESYVdlgiKKVNWKKSKVNSIVQQEDPNEELSKD-EFIL------------KLKAEVQRLLGSNSMKRRLVSQLQ 570
Cdd:pfam05483  224 IQhLEEEYK----KEINDKEKQVSLLLIQITEKENKMKDlTFLLeesrdkanqleeKTKLQDENLKELIEKKDHLTKELE 299
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  571 nDLKDCHKKIEDLHQVKRDEKSIEVETKTDTSEKPKNQLwlesSTSDIVRDDILLLKNEIQVLQQQNQELKETEEKLRNT 650
Cdd:pfam05483  300 -DIKMSLQRSMSTQKALEEDLQIATKTICQLTEEKEAQM----EELNKAKAAHSFVVTEFEATTCSLEELLRTEQQRLEK 374
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  651 NQDlcnQMRQMVQDFdhdKREAVDRCERTYQQHHEAMKTQIRESLLAkhalEKQQLFEAYERTHlQLRSELDKVNKEMTa 730
Cdd:pfam05483  375 NED---QLKIITMEL---QKKSSELEEMTKFKNNKEVELEELKKILA----EDEKLLDEKKQFE-KIAEELKGKEQELI- 442
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  731 vqecYLEVCREKD--HLESTLRKTTEKEQQTQEKlleereeyVSKLQVELEK-KYQDTLMMEKSKWLKDQETDIKQQVEN 807
Cdd:pfam05483  443 ----FLLQAREKEihDLEIQLTAIKTSEEHYLKE--------VEDLKTELEKeKLKNIELTAHCDKLLLENKELTQEASD 510
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  808 EVILAKAHWDK--EQKEIKEKLIQQLE--KEWQSKLDQTIKAMKKKTSDRGsqtdqvttsdviskkemaimiEEQKCIIQ 883
Cdd:pfam05483  511 MTLELKKHQEDiiNCKKQEERMLKQIEnlEEKEMNLRDELESVREEFIQKG---------------------DEVKCKLD 569
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  884 QHLEQEKDIAIKGAMKKLEIELELKHCENIAKQVEiavqnARQRWLGELPELAEYQALVRAEQKKWEEQHEVSVNKrISF 963
Cdd:pfam05483  570 KSEENARSIEYEVLKKEKQMKILENKCNNLKKQIE-----NKNKNIEELHQENKALKKKGSAENKQLNAYEIKVNK-LEL 643
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  964 AVSEAKEKWKSELENMKKNILPGTELEEKIH--------------SLQRELELKNEEVPVVIRAELAKARSEWNKEKQEE 1029
Cdd:pfam05483  644 ELASAKQKFEEIIDNYQKEIEDKKISEEKLLeevekakaiadeavKLQKEIDKRCQHKIAEMVALMEKHKHQYDKIIEER 723
                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*
gi 1622953050 1030 -----IRRIQEQNEQDYRQFLDDHRNKINEVLAAAKEDFMKQKTE 1069
Cdd:pfam05483  724 dselgLYKNKEQEQSSAKAALEIELSNIKAELLSLKKQLEIEKEE 768
COG5022 COG5022
Myosin heavy chain [General function prediction only];
537-828 3.17e-03

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 42.37  E-value: 3.17e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  537 EELSKDEFILKLKAEVQrllgsNSMKRrlvsqlQNDLKDCHKKIEDLHQV--KRDEKSIEVETKTDTSEKPKNQLWLESS 614
Cdd:COG5022    862 SLLKKETIYLQSAQRVE-----LAERQ------LQELKIDVKSISSLKLVnlELESEIIELKKSLSSDLIENLEFKTELI 930
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  615 TsdivRDDILLLKNEIQVLQQQNQELKETEEKLRNTNQDLcnqmrqmvqdfdhdkreavdrcertyqqhHEAmkTQIRES 694
Cdd:COG5022    931 A----RLKKLLNNIDLEEGPSIEYVKLPELNKLHEVESKL-----------------------------KET--SEEYED 975
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  695 LLAKHalekqqlfEAYERTHLQLRSELDKVNKEMTAVQECYLEVCREKDHLESTLRKTTEKEQQTQeKLLEEREEyvskL 774
Cdd:COG5022    976 LLKKS--------TILVREGNKANSELKNFKKELAELSKQYGALQESTKQLKELPVEVAELQSASK-IISSESTE----L 1042
                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1622953050  775 QVELEKKYQDTLMMEKSKWLKDQETDIKQQVENEVILAKAHWDKEQKEIKEKLI 828
Cdd:COG5022   1043 SILKPLQKLKGLLLLENNQLQARYKALKLRRENSLLDDKQLYQLESTENLLKTI 1096
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
352-1001 3.78e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 41.97  E-value: 3.78e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  352 ESLQRAREQHESVVMGLT--KKYE---EQVLSLQKNLDATVTALKE----QEDICSRLKDHVKQLERNQEAIKlEKTEII 422
Cdd:PRK03918   138 DAILESDESREKVVRQILglDDYEnayKNLGEVIKEIKRRIERLEKfikrTENIEELIKEKEKELEEVLREIN-EISSEL 216
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  423 NRLTRSLEESQKQCAHLLQSGSvqEVAQLQFQLQQAQKAHTMSENMNKALQEELTELKDEISLYESAAKlGIHPSDSEGE 502
Cdd:PRK03918   217 PELREELEKLEKEVKELEELKE--EIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVK-ELKELKEKAE 293
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  503 LNIELTESYVDLGIKKVNWKK------SKVNSIVQQ-EDPNEELSKDEFILKLKAEVQRLLgsnsmkrrlvsqlqNDLKD 575
Cdd:PRK03918   294 EYIKLSEFYEEYLDELREIEKrlsrleEEINGIEERiKELEEKEERLEELKKKLKELEKRL--------------EELEE 359
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  576 CHKKIEDLHQVKRDEKSIEVETKTDTSEKPKNQLWLESSTSDIVRDDILLLKNEIQVLQQQNQELKETEEKLRNTnqdlc 655
Cdd:PRK03918   360 RHELYEEAKAKKEELERLKKRLTGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKA----- 434
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  656 nqmrqmvqdfdhdkREAVDRCERTYQQHHeamktqiRESLLAKHALEkqqlfeayerthlqlrseLDKVNKEMTAVQECY 735
Cdd:PRK03918   435 --------------KGKCPVCGRELTEEH-------RKELLEEYTAE------------------LKRIEKELKEIEEKE 475
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  736 LEVCREKDHLESTLRKttEKEQQTQEKLLEEREEYVSKLQV----ELEKKYQD-TLMMEKSKWLKDQETDIKQQVE--NE 808
Cdd:PRK03918   476 RKLRKELRELEKVLKK--ESELIKLKELAEQLKELEEKLKKynleELEKKAEEyEKLKEKLIKLKGEIKSLKKELEklEE 553
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  809 VILAKAHWDKEQKEIKEKLiQQLEKEWQSKLDQTIKAMKKKTSDRGSQTDQVTTSdVISKKEMAIMIEEQKciiqqHLEQ 888
Cdd:PRK03918   554 LKKKLAELEKKLDELEEEL-AELLKELEELGFESVEELEERLKELEPFYNEYLEL-KDAEKELEREEKELK-----KLEE 626
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  889 EKDIAIKgamkklEIELELKHCENIAKQVEIAVQNARQ----RWLGELPELAEYQALVRAEQKKWEEQHEvSVNKRISF- 963
Cdd:PRK03918   627 ELDKAFE------ELAETEKRLEELRKELEELEKKYSEeeyeELREEYLELSRELAGLRAELEELEKRRE-EIKKTLEKl 699
                          650       660       670
                   ....*....|....*....|....*....|....*....
gi 1622953050  964 -AVSEAKEKWKSELENMKKNILPGTELEEKIHSLQRELE 1001
Cdd:PRK03918   700 kEELEEREKAKKELEKLEKALERVEELREKVKKYKALLK 738
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
237-532 5.03e-03

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 41.54  E-value: 5.03e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  237 NMQIIQLQVLNKAKERQLENLVEKLNESECQIRYLNHQLVIIKDEKDGLTLSLRESQKLFQNGKEREIQLEAQIKALETQ 316
Cdd:TIGR04523  341 NEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQE 420
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  317 IQaLKVNEEQMIKKSRTTEMA-LESLKQQLVDLHHS-ESLQRAREQHESVVMGLTKKYEeqvlSLQKNLDATVTALKEQE 394
Cdd:TIGR04523  421 KE-LLEKEIERLKETIIKNNSeIKDLTNQDSVKELIiKNLDNTRESLETQLKVLSRSIN----KIKQNLEQKQKELKSKE 495
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  395 DICSRLKDHVKQLER--------------NQEAIKLEKTEIINRLTRSLEESQKQCAHLLQSGSVQEVAQLQFQLQQAQK 460
Cdd:TIGR04523  496 KELKKLNEEKKELEEkvkdltkkisslkeKIEKLESEKKEKESKISDLEDELNKDDFELKKENLEKEIDEKNKEIEELKQ 575
                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1622953050  461 AHTMSENMNKALQEELTELKDEIS-LYESAAKLGIHPSDSEGELN-IELTESYVDLGIKKVNWKKSKVNSIVQQ 532
Cdd:TIGR04523  576 TQKSLKKKQEEKQELIDQKEKEKKdLIKEIEEKEKKISSLEKELEkAKKENEKLSSIIKNIKSKKNKLKQEVKQ 649
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
691-1107 7.50e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 40.91  E-value: 7.50e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  691 IRESLLAKHALEKQQLFEAYERTHLQLRSELDKVNKEMTAVQEcylevcrekdhlestlrktTEKEQQTQEKLLEEREEY 770
Cdd:COG4717     43 IRAMLLERLEKEADELFKPQGRKPELNLKELKELEEELKEAEE-------------------KEEEYAELQEELEELEEE 103
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  771 VSKLQVELEKKYQDTLMMEKSKWLKDQETDiKQQVENEVILAKAHWDKEQKEIKEklIQQLEKEWQSkLDQTIKAMKKKT 850
Cdd:COG4717    104 LEELEAELEELREELEKLEKLLQLLPLYQE-LEALEAELAELPERLEELEERLEE--LRELEEELEE-LEAELAELQEEL 179
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  851 SDRGSQTDQVTTSDVISKKEMAIMIEEQKCIIQQHLE--QEKDIAIKGAMKKLEIELELKHCENIAKQVEI--------- 919
Cdd:COG4717    180 EELLEQLSLATEEELQDLAEELEELQQRLAELEEELEeaQEELEELEEELEQLENELEAAALEERLKEARLllliaaall 259
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  920 AVQNARQRWLGELPELAEYQALV------------RAEQKKWEEQHEVSVNKRISFAVSEAKEKWKSELenMKKNILPGT 987
Cdd:COG4717    260 ALLGLGGSLLSLILTIAGVLFLVlgllallflllaREKASLGKEAEELQALPALEELEEEELEELLAAL--GLPPDLSPE 337
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  988 ELEEKIHSLQRELELKNEEVPVVIRAELAKARSEWNK-------EKQEEIRRIQEQNE--QDYRQFLDDHRNKINEVLAA 1058
Cdd:COG4717    338 ELLELLDRIEELQELLREAEELEEELQLEELEQEIAAllaeagvEDEEELRAALEQAEeyQELKEELEELEEQLEELLGE 417
                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1622953050 1059 AKEDFMKQKTELLLQKETELQTCLD--QSRREWTMQEAKRIQLEIYQYEED 1107
Cdd:COG4717    418 LEELLEALDEEELEEELEELEEELEelEEELEELREELAELEAELEQLEED 468
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
239-412 8.13e-03

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 41.31  E-value: 8.13e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  239 QIIQLQVLNKAKERQLENLVEKLNESECQIRYLNHQL-----VIIKDEKDGLTLS--LRESQKLFQNGKEREIQLEAQIK 311
Cdd:pfam01576  413 QLQELQARLSESERQRAELAEKLSKLQSELESVSSLLneaegKNIKLSKDVSSLEsqLQDTQELLQEETRQKLNLSTRLR 492
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622953050  312 ALETQIQALKVNEEQMIKKSRTTEMALESLKQQLVDLHHS--------ESLQRAREQHESVVMGLTKKYEEQVLSLQKnL 383
Cdd:pfam01576  493 QLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKleedagtlEALEEGKKRLQRELEALTQQLEEKAAAYDK-L 571
                          170       180
                   ....*....|....*....|....*....
gi 1622953050  384 DATVTALKEQEDICSRLKDHVKQLERNQE 412
Cdd:pfam01576  572 EKTKNRLQQELDDLLVDLDHQRQLVSNLE 600
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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