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Conserved domains on  [gi|966950428|ref|XP_014997138|]
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zinc finger protein 62 homolog isoform X4 [Macaca mulatta]

Protein Classification

C2H2-type zinc finger protein( domain architecture ID 11472214)

Cys2His2 (C2H2)-type zinc finger protein may be involved in transcriptional regulation

CATH:  3.30.160.60
Gene Ontology:  GO:0008270|GO:0003677
PubMed:  11361095|22803940
SCOP:  4003583

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
387-800 2.24e-10

FOG: Zn-finger [General function prediction only];


:

Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 63.95  E-value: 2.24e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966950428 387 RPYVCDVCGKTFRNNAGLKVHRRLHTGEKPYKCDV--CGKAYISRSSLKNHKGIHLGEKPYKCSYCEKSFNYSSALEQHK 464
Cdd:COG5048   32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYsgCDKSFSRPLELSRHLRTHHNNPSDLNSKSLPLSNSKASSSSLS 111

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966950428 465 R-IHTREKPFGCDECGKAFRNNSGLKVHKRIHTGERPYKCEEC------GKAYISLSSLINHKSVHPGEKPFKCDECEKA 537
Cdd:COG5048  112 SsSSNSNDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNnsssvnTPQSNSLHPPLPANSLSKDPSSNLSLLISSN 191

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966950428 538 FITyrTLINHKKVHLGEKPYKCDVC---EKSFNYTSLLSQHKRVHTREKPYecDRCEKVFRNNSSLKVHKRIHtgekpYE 614
Cdd:COG5048  192 VST--SIPSSSENSPLSSSYSIPSSssdQNLENSSSSLPLTTNSQLSPKSL--LSQSPSSLSSSDSSSSASES-----PR 262

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966950428 615 CDVCGKAYISHSSLINHKSTHPGKT-PHPCDECGKAFFSSRTLISHKR--VHLGE--KPFKCVE--CGKSFSYSSLLSQH 687
Cdd:COG5048  263 SSLPTASSQSSSPNESDSSSEKGFSlPIKSKQCNISFSRSSPLTRHLRsvNHSGEslKPFSCPYslCGKLFSRNDALKRH 342

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966950428 688 KRVHTGEKPYVC--DRCGKAFR-----NSSGLTVHKRIHTGEKPYECD--ECGKAYISHSSLINHKSVHQGKQPYNCE-- 756
Cdd:COG5048  343 ILLHTSISPAKEklLNSSSKFSpllnnEPPQSLQQYKDLKNDKKSETLsnSCIRNFKRDSNLSLHIITHLSFRPYNCKnp 422

                        410       420       430       440
                 ....*....|....*....|....*....|....*....|....*
gi 966950428 757 -CGKSFNYRSVLDQHKRIHTGRKPYRCNECGKaFNIRSNLTKHKR 800
Cdd:COG5048  423 pCSKSFNRHYNLIPHKKIHTNHAPLLCSILKS-FRRDLDLSNHGK 466
SFP1 super family cl25788
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 329-408 5.72e-09

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


The actual alignment was detected with superfamily member COG5189:

Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 59.35  E-value: 5.72e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966950428 329 GEKPYKCDV--CGKAFSYSSGLAVHKsihpgKKAHeckeCGKSFSYNSLLLQHRTIHTGERPYVCDVCGKTFRNNAGLKV 406
Cdd:COG5189  346 DGKPYKCPVegCNKKYKNQNGLKYHM-----LHGH----QNQKLHENPSPEKMNIFSAKDKPYRCEVCDKRYKNLNGLKY 416


                 ..
gi 966950428 407 HR 408
Cdd:COG5189  417 HR 418
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
65-492 1.09e-08

FOG: Zn-finger [General function prediction only];


:

Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 58.55  E-value: 1.09e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966950428  65 TSHPTLQQKTNAVKKLHKCDECGKSFKYNSRLVQHKIMHTGEKRYECDDCGGT--FRSSSSLRVHKRIHTGEKPYACEEC 142
Cdd:COG5048   18 STPKSTLKSLSNAPRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDksFSRPLELSRHLRTHHNNPSDLNSKS 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966950428 143 GKAYMSY--SSLINHKSTHS--GEKNCKCDECGKSFNYSSVLDQHKRIHTGEKPYECGECGKAFRNSSGLRVHKRIHtge 218
Cdd:COG5048   98 LPLSNSKasSSSLSSSSSNSndNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQSNSLHPPLPAN--- 174

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966950428 219 kpyecdICGKTFSNSSGLRVHKRIHTGEKPYECDECGKAFITCRTLLNHKSIHFGDKPYKCDECEKSFNYSSLLIQHKVI 298
Cdd:COG5048  175 ------SLSKDPSSNLSLLISSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSL 248

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966950428 299 HTGEKPYECDECGKAFRNSSGLIVHKRIHTGE-------KPYKCDVCGKAFSYSSGLAVHK--SIHPGK--KAHECKE-- 365
Cdd:COG5048  249 SSSDSSSSASESPRSSLPTASSQSSSPNESDSssekgfsLPIKSKQCNISFSRSSPLTRHLrsVNHSGEslKPFSCPYsl 328

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966950428 366 CGKSFSYNSLLLQHRTIHTGERPYVC--DVCGKTFR-----NNAGLKVHRRLHTGEKPYKCDV--CGKAYISRSSLKNHK 436
Cdd:COG5048  329 CGKLFSRNDALKRHILLHTSISPAKEklLNSSSKFSpllnnEPPQSLQQYKDLKNDKKSETLSnsCIRNFKRDSNLSLHI 408

                        410       420       430       440       450
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 966950428 437 GIHLGEKP--YKCSYCEKSFNYSSALEQHKRIHTREKPFGCDECGKAFRNNSGLKVHK 492
Cdd:COG5048  409 ITHLSFRPynCKNPPCSKSFNRHYNLIPHKKIHTNHAPLLCSILKSFRRDLDLSNHGK 466
 
Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
387-800 2.24e-10

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 63.95  E-value: 2.24e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966950428 387 RPYVCDVCGKTFRNNAGLKVHRRLHTGEKPYKCDV--CGKAYISRSSLKNHKGIHLGEKPYKCSYCEKSFNYSSALEQHK 464
Cdd:COG5048   32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYsgCDKSFSRPLELSRHLRTHHNNPSDLNSKSLPLSNSKASSSSLS 111

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966950428 465 R-IHTREKPFGCDECGKAFRNNSGLKVHKRIHTGERPYKCEEC------GKAYISLSSLINHKSVHPGEKPFKCDECEKA 537
Cdd:COG5048  112 SsSSNSNDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNnsssvnTPQSNSLHPPLPANSLSKDPSSNLSLLISSN 191

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966950428 538 FITyrTLINHKKVHLGEKPYKCDVC---EKSFNYTSLLSQHKRVHTREKPYecDRCEKVFRNNSSLKVHKRIHtgekpYE 614
Cdd:COG5048  192 VST--SIPSSSENSPLSSSYSIPSSssdQNLENSSSSLPLTTNSQLSPKSL--LSQSPSSLSSSDSSSSASES-----PR 262

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966950428 615 CDVCGKAYISHSSLINHKSTHPGKT-PHPCDECGKAFFSSRTLISHKR--VHLGE--KPFKCVE--CGKSFSYSSLLSQH 687
Cdd:COG5048  263 SSLPTASSQSSSPNESDSSSEKGFSlPIKSKQCNISFSRSSPLTRHLRsvNHSGEslKPFSCPYslCGKLFSRNDALKRH 342

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966950428 688 KRVHTGEKPYVC--DRCGKAFR-----NSSGLTVHKRIHTGEKPYECD--ECGKAYISHSSLINHKSVHQGKQPYNCE-- 756
Cdd:COG5048  343 ILLHTSISPAKEklLNSSSKFSpllnnEPPQSLQQYKDLKNDKKSETLsnSCIRNFKRDSNLSLHIITHLSFRPYNCKnp 422

                        410       420       430       440
                 ....*....|....*....|....*....|....*....|....*
gi 966950428 757 -CGKSFNYRSVLDQHKRIHTGRKPYRCNECGKaFNIRSNLTKHKR 800
Cdd:COG5048  423 pCSKSFNRHYNLIPHKKIHTNHAPLLCSILKS-FRRDLDLSNHGK 466
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 329-408 5.72e-09

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 59.35  E-value: 5.72e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966950428 329 GEKPYKCDV--CGKAFSYSSGLAVHKsihpgKKAHeckeCGKSFSYNSLLLQHRTIHTGERPYVCDVCGKTFRNNAGLKV 406
Cdd:COG5189  346 DGKPYKCPVegCNKKYKNQNGLKYHM-----LHGH----QNQKLHENPSPEKMNIFSAKDKPYRCEVCDKRYKNLNGLKY 416


                 ..
gi 966950428 407 HR 408
Cdd:COG5189  417 HR 418
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
65-492 1.09e-08

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 58.55  E-value: 1.09e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966950428  65 TSHPTLQQKTNAVKKLHKCDECGKSFKYNSRLVQHKIMHTGEKRYECDDCGGT--FRSSSSLRVHKRIHTGEKPYACEEC 142
Cdd:COG5048   18 STPKSTLKSLSNAPRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDksFSRPLELSRHLRTHHNNPSDLNSKS 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966950428 143 GKAYMSY--SSLINHKSTHS--GEKNCKCDECGKSFNYSSVLDQHKRIHTGEKPYECGECGKAFRNSSGLRVHKRIHtge 218
Cdd:COG5048   98 LPLSNSKasSSSLSSSSSNSndNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQSNSLHPPLPAN--- 174

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966950428 219 kpyecdICGKTFSNSSGLRVHKRIHTGEKPYECDECGKAFITCRTLLNHKSIHFGDKPYKCDECEKSFNYSSLLIQHKVI 298
Cdd:COG5048  175 ------SLSKDPSSNLSLLISSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSL 248

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966950428 299 HTGEKPYECDECGKAFRNSSGLIVHKRIHTGE-------KPYKCDVCGKAFSYSSGLAVHK--SIHPGK--KAHECKE-- 365
Cdd:COG5048  249 SSSDSSSSASESPRSSLPTASSQSSSPNESDSssekgfsLPIKSKQCNISFSRSSPLTRHLrsVNHSGEslKPFSCPYsl 328

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966950428 366 CGKSFSYNSLLLQHRTIHTGERPYVC--DVCGKTFR-----NNAGLKVHRRLHTGEKPYKCDV--CGKAYISRSSLKNHK 436
Cdd:COG5048  329 CGKLFSRNDALKRHILLHTSISPAKEklLNSSSKFSpllnnEPPQSLQQYKDLKNDKKSETLSnsCIRNFKRDSNLSLHI 408

                        410       420       430       440       450
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 966950428 437 GIHLGEKP--YKCSYCEKSFNYSSALEQHKRIHTREKPFGCDECGKAFRNNSGLKVHK 492
Cdd:COG5048  409 ITHLSFRPynCKNPPCSKSFNRHYNLIPHKKIHTNHAPLLCSILKSFRRDLDLSNHGK 466
SUF4-like cd20908
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
 443-491 3.37e-04

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 39.85  E-value: 3.37e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*....
gi 966950428 443 KPYkCSYCEKSFNYSSALEQHKRIHTrekpFGCDECGKAFRNNSGLKVH 491
Cdd:cd20908    1 KPW-CYYCDREFDDEKILIQHQKAKH----FKCHICHKKLYTAGGLAVH 44
zf-H2C2_2 pfam13465
Zinc-finger double domain;
236-260 3.96e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 38.12  E-value: 3.96e-04
                          10        20
                  ....*....|....*....|....*
gi 966950428  236 LRVHKRIHTGEKPYECDECGKAFIT 260
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
320-344 1.04e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.97  E-value: 1.04e-03
                          10        20
                  ....*....|....*....|....*
gi 966950428  320 LIVHKRIHTGEKPYKCDVCGKAFSY 344
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
599-624 1.50e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.58  E-value: 1.50e-03
                          10        20
                  ....*....|....*....|....*.
gi 966950428  599 SLKVHKRIHTGEKPYECDVCGKAYIS 624
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
SUF4-like cd20908
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
 303-351 6.49e-03

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 36.38  E-value: 6.49e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*....
gi 966950428 303 KPYeCDECGKAFRNSSGLIVHKRIHTgekpYKCDVCGKAFSYSSGLAVH 351
Cdd:cd20908    1 KPW-CYYCDREFDDEKILIQHQKAKH----FKCHICHKKLYTAGGLAVH 44
 
Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
387-800 2.24e-10

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 63.95  E-value: 2.24e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966950428 387 RPYVCDVCGKTFRNNAGLKVHRRLHTGEKPYKCDV--CGKAYISRSSLKNHKGIHLGEKPYKCSYCEKSFNYSSALEQHK 464
Cdd:COG5048   32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYsgCDKSFSRPLELSRHLRTHHNNPSDLNSKSLPLSNSKASSSSLS 111

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966950428 465 R-IHTREKPFGCDECGKAFRNNSGLKVHKRIHTGERPYKCEEC------GKAYISLSSLINHKSVHPGEKPFKCDECEKA 537
Cdd:COG5048  112 SsSSNSNDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNnsssvnTPQSNSLHPPLPANSLSKDPSSNLSLLISSN 191

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966950428 538 FITyrTLINHKKVHLGEKPYKCDVC---EKSFNYTSLLSQHKRVHTREKPYecDRCEKVFRNNSSLKVHKRIHtgekpYE 614
Cdd:COG5048  192 VST--SIPSSSENSPLSSSYSIPSSssdQNLENSSSSLPLTTNSQLSPKSL--LSQSPSSLSSSDSSSSASES-----PR 262

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966950428 615 CDVCGKAYISHSSLINHKSTHPGKT-PHPCDECGKAFFSSRTLISHKR--VHLGE--KPFKCVE--CGKSFSYSSLLSQH 687
Cdd:COG5048  263 SSLPTASSQSSSPNESDSSSEKGFSlPIKSKQCNISFSRSSPLTRHLRsvNHSGEslKPFSCPYslCGKLFSRNDALKRH 342

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966950428 688 KRVHTGEKPYVC--DRCGKAFR-----NSSGLTVHKRIHTGEKPYECD--ECGKAYISHSSLINHKSVHQGKQPYNCE-- 756
Cdd:COG5048  343 ILLHTSISPAKEklLNSSSKFSpllnnEPPQSLQQYKDLKNDKKSETLsnSCIRNFKRDSNLSLHIITHLSFRPYNCKnp 422

                        410       420       430       440
                 ....*....|....*....|....*....|....*....|....*
gi 966950428 757 -CGKSFNYRSVLDQHKRIHTGRKPYRCNECGKaFNIRSNLTKHKR 800
Cdd:COG5048  423 pCSKSFNRHYNLIPHKKIHTNHAPLLCSILKS-FRRDLDLSNHGK 466
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
303-716 2.13e-09

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 60.86  E-value: 2.13e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966950428 303 KPYECDECGKAFRNSSGLIVHKRIHTGEKPYKCDVCGKAFSYSSGLA--VHKSIHPGKKAHEC-KECGKSFSYNSLLLQH 379
Cdd:COG5048   32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDKSFSRPLElsRHLRTHHNNPSDLNsKSLPLSNSKASSSSLS 111

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966950428 380 RTIHTGERPYVCDVCGKTFRNNAGLKVHRRLHTGEKPYKCDVCGKAYISR----SSLKNHKGIHLGEKPYKCSYCE---- 451
Cdd:COG5048  112 SSSSNSNDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTpqsnSLHPPLPANSLSKDPSSNLSLLissn 191

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966950428 452 KSFNYSSALEQHKRIHTREKPFGCDECGKaFRNNSGLKVHKRIHTGERPYKCEecgkayislssliNHKSVHPGEKPFKC 531
Cdd:COG5048  192 VSTSIPSSSENSPLSSSYSIPSSSSDQNL-ENSSSSLPLTTNSQLSPKSLLSQ-------------SPSSLSSSDSSSSA 257

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966950428 532 DECEKAFITYRTLINHKKVHLGE-------KPYKCDVCEKSFNYTSLLSQHKR--VHTRE--KPYECD--RCEKVFRNNS 598
Cdd:COG5048  258 SESPRSSLPTASSQSSSPNESDSssekgfsLPIKSKQCNISFSRSSPLTRHLRsvNHSGEslKPFSCPysLCGKLFSRND 337

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966950428 599 SLKVHKRIHTGEKPYEC--DVCGKAYI------SHSSLINHKSTHPGKTPHPCDECGKAFFSSR-TLISHKRVHLGEKP- 668
Cdd:COG5048  338 ALKRHILLHTSISPAKEklLNSSSKFSpllnnePPQSLQQYKDLKNDKKSETLSNSCIRNFKRDsNLSLHIITHLSFRPy 417

                        410       420       430       440
                 ....*....|....*....|....*....|....*....|....*....
gi 966950428 669 -FKCVECGKSFSYSSLLSQHKRVHTGEKPYVCDRCGKAFRNSSGLTVHK 716
Cdd:COG5048  418 nCKNPPCSKSFNRHYNLIPHKKIHTNHAPLLCSILKSFRRDLDLSNHGK 466
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
219-605 3.02e-09

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 60.09  E-value: 3.02e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966950428 219 KPYECDICGKTFSNSSGLRVHKRIHTGEKPYECDECGKAFITCRTLLNHKSI------------------HFGDKPYKCD 280
Cdd:COG5048   32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDKSFSRPLELSRHLrthhnnpsdlnskslplsNSKASSSSLS 111

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966950428 281 ECEKSFNYSSLLIQHKVIHTGEKPYECDECGKAFRNSSGLIVHKRIHTGEK-------PYKCDVCGKAFSYSSGLAVHKS 353
Cdd:COG5048  112 SSSSNSNDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPqsnslhpPLPANSLSKDPSSNLSLLISSN 191

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966950428 354 IHPGKKAHECKECGKSFSYNSLLLQHRTIHTGERPYVCDVCgkTFRNNAGLKVHRRLHTGEKPYK--CDVCGKAYISRSS 431
Cdd:COG5048  192 VSTSIPSSSENSPLSSSYSIPSSSSDQNLENSSSSLPLTTN--SQLSPKSLLSQSPSSLSSSDSSssASESPRSSLPTAS 269

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966950428 432 LKNHKGIHLGE-------KPYKCSYCEKSFNYSSALEQHKR--IHTRE--KPFGCDE--CGKAFRNNSGLKVHKRIHTGE 498
Cdd:COG5048  270 SQSSSPNESDSssekgfsLPIKSKQCNISFSRSSPLTRHLRsvNHSGEslKPFSCPYslCGKLFSRNDALKRHILLHTSI 349

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966950428 499 RPYKC--EECGKAYISLSSLINHKSVHP-----GEKPFKCD--ECEKAFITYRTLINHKKVHLGEKP--YKCDVCEKSFN 567
Cdd:COG5048  350 SPAKEklLNSSSKFSPLLNNEPPQSLQQykdlkNDKKSETLsnSCIRNFKRDSNLSLHIITHLSFRPynCKNPPCSKSFN 429

                        410       420       430
                 ....*....|....*....|....*....|....*...
gi 966950428 568 YTSLLSQHKRVHTREKPYECdRCEKVFRNNSSLKVHKR 605
Cdd:COG5048  430 RHYNLIPHKKIHTNHAPLLC-SILKSFRRDLDLSNHGK 466
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 329-408 5.72e-09

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 59.35  E-value: 5.72e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966950428 329 GEKPYKCDV--CGKAFSYSSGLAVHKsihpgKKAHeckeCGKSFSYNSLLLQHRTIHTGERPYVCDVCGKTFRNNAGLKV 406
Cdd:COG5189  346 DGKPYKCPVegCNKKYKNQNGLKYHM-----LHGH----QNQKLHENPSPEKMNIFSAKDKPYRCEVCDKRYKNLNGLKY 416


                 ..
gi 966950428 407 HR 408
Cdd:COG5189  417 HR 418
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
135-550 8.35e-09

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 58.94  E-value: 8.35e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966950428 135 KPYACEECGKAYMSYSSLINHKSTHSGEKNCKC--DECGKSFNYSSVLDQHKRIHTGEKPYECgeCGKAFRNSSGLRVHK 212
Cdd:COG5048   32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSDLN--SKSLPLSNSKASSSS 109

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966950428 213 RIHTGEKPYECDIC-GKTFSNSSGLRVHKRIHTGEKPYECDECGKAFITCRTLLNHKSIHfgDKPYKCdECEKSFNYSSL 291
Cdd:COG5048  110 LSSSSSNSNDNNLLsSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQSNSLHP--PLPANS-LSKDPSSNLSL 186

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966950428 292 LIQHKVIHTGEKPYECDECGKAFRNSSGLIVHKRIHTgEKPYKCDVCGKAFSYSSGLAVHKSIHPGKKAHECKECGKSFS 371
Cdd:COG5048  187 LISSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENS-SSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESPRSSL 265

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966950428 372 YNSLLLQHRTIHTGER-------PYVCDVCGKTFRNNAGLKVHRR--LHTGE--KPYKCDV--CGKAYISRSSLKNHKGI 438
Cdd:COG5048  266 PTASSQSSSPNESDSSsekgfslPIKSKQCNISFSRSSPLTRHLRsvNHSGEslKPFSCPYslCGKLFSRNDALKRHILL 345

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966950428 439 HLGEKPYKCSYCEKSFNYSSAL-------EQHKRIHTREKPFGCD--ECGKAFRNNSGLKVHKRIHTGERP--YKCEECG 507
Cdd:COG5048  346 HTSISPAKEKLLNSSSKFSPLLnneppqsLQQYKDLKNDKKSETLsnSCIRNFKRDSNLSLHIITHLSFRPynCKNPPCS 425

                        410       420       430       440
                 ....*....|....*....|....*....|....*....|...
gi 966950428 508 KAYISLSSLINHKSVHPGEKPFKCdECEKAFITYRTLINHKKV 550
Cdd:COG5048  426 KSFNRHYNLIPHKKIHTNHAPLLC-SILKSFRRDLDLSNHGKD 467
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 408-492 1.03e-08

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 58.19  E-value: 1.03e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966950428 408 RRLHT-GEKPYKCDV--CGKAYISRSSLKNHKgihlgekpyKCSYCEKSFNYSSALEQHKRIHTREKPFGCDECGKAFRN 484
Cdd:COG5189  340 RMLKVkDGKPYKCPVegCNKKYKNQNGLKYHM---------LHGHQNQKLHENPSPEKMNIFSAKDKPYRCEVCDKRYKN 410


                 ....*...
gi 966950428 485 NSGLKVHK 492
Cdd:COG5189  411 LNGLKYHR 418
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
65-492 1.09e-08

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 58.55  E-value: 1.09e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966950428  65 TSHPTLQQKTNAVKKLHKCDECGKSFKYNSRLVQHKIMHTGEKRYECDDCGGT--FRSSSSLRVHKRIHTGEKPYACEEC 142
Cdd:COG5048   18 STPKSTLKSLSNAPRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDksFSRPLELSRHLRTHHNNPSDLNSKS 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966950428 143 GKAYMSY--SSLINHKSTHS--GEKNCKCDECGKSFNYSSVLDQHKRIHTGEKPYECGECGKAFRNSSGLRVHKRIHtge 218
Cdd:COG5048   98 LPLSNSKasSSSLSSSSSNSndNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQSNSLHPPLPAN--- 174

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966950428 219 kpyecdICGKTFSNSSGLRVHKRIHTGEKPYECDECGKAFITCRTLLNHKSIHFGDKPYKCDECEKSFNYSSLLIQHKVI 298
Cdd:COG5048  175 ------SLSKDPSSNLSLLISSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSL 248

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966950428 299 HTGEKPYECDECGKAFRNSSGLIVHKRIHTGE-------KPYKCDVCGKAFSYSSGLAVHK--SIHPGK--KAHECKE-- 365
Cdd:COG5048  249 SSSDSSSSASESPRSSLPTASSQSSSPNESDSssekgfsLPIKSKQCNISFSRSSPLTRHLrsVNHSGEslKPFSCPYsl 328

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966950428 366 CGKSFSYNSLLLQHRTIHTGERPYVC--DVCGKTFR-----NNAGLKVHRRLHTGEKPYKCDV--CGKAYISRSSLKNHK 436
Cdd:COG5048  329 CGKLFSRNDALKRHILLHTSISPAKEklLNSSSKFSpllnnEPPQSLQQYKDLKNDKKSETLSnsCIRNFKRDSNLSLHI 408

                        410       420       430       440       450
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 966950428 437 GIHLGEKP--YKCSYCEKSFNYSSALEQHKRIHTREKPFGCDECGKAFRNNSGLKVHK 492
Cdd:COG5048  409 ITHLSFRPynCKNPPCSKSFNRHYNLIPHKKIHTNHAPLLCSILKSFRRDLDLSNHGK 466
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
443-803 5.26e-07

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 53.16  E-value: 5.26e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966950428 443 KPYKCSYCEKSFNYSSALEQHKRIHTREKPFGC--DECGKAFRNNSGLKVHKRIHTGERPYKCE--ECGKAYISLSSLIN 518
Cdd:COG5048   32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSDLNSksLPLSNSKASSSSLS 111

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966950428 519 HKSVHPgEKPFKCDECEKAFITYRTLIN--HKKVHLGEKPYKcdVCEKSF----NYTSLLSQHKRVHTREKPYECDRCEK 592
Cdd:COG5048  112 SSSSNS-NDNNLLSSHSLPPSSRDPQLPdlLSISNLRNNPLP--GNNSSSvntpQSNSLHPPLPANSLSKDPSSNLSLLI 188

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966950428 593 VFRNNSSLKVHKRIHTGEKPYECDVCGKAYISHSSLINHKSTHPGKTPHP------------------CDECGKAFFSSR 654
Cdd:COG5048  189 SSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENSSSSLPLTTNSQLSPKsllsqspsslsssdssssASESPRSSLPTA 268

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966950428 655 TLISHKRVHLGE-------KPFKCVECGKSFSYSSLLSQHKR--VHTGE--KPYVCD--RCGKAFRNSSGLTVHKRIHTG 721
Cdd:COG5048  269 SSQSSSPNESDSssekgfsLPIKSKQCNISFSRSSPLTRHLRsvNHSGEslKPFSCPysLCGKLFSRNDALKRHILLHTS 348

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966950428 722 EKPYECDEC--------GKAYISHSSLINHKSVHQGKQPYNC--ECGKSFNYRSVLDQHKRIHTGRKP--YRCNECGKAF 789
Cdd:COG5048  349 ISPAKEKLLnssskfspLLNNEPPQSLQQYKDLKNDKKSETLsnSCIRNFKRDSNLSLHIITHLSFRPynCKNPPCSKSF 428

                        410
                 ....*....|....
gi 966950428 790 NIRSNLTKHKRTHT 803
Cdd:COG5048  429 NRHYNLIPHKKIHT 442
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 385-437 3.67e-06

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 50.10  E-value: 3.67e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 966950428 385 GERPYVCDV--CGKTFRNNAGLKVHRrLH--------------------TGEKPYKCDVCGKAYISRSSLKNHKG 437
Cdd:COG5189  346 DGKPYKCPVegCNKKYKNQNGLKYHM-LHghqnqklhenpspekmnifsAKDKPYRCEVCDKRYKNLNGLKYHRK 419
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 189-240 2.84e-05

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 47.41  E-value: 2.84e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 966950428 189 GEKPYECG--ECGKAFRNSSGLRVHKR-------------------IHTGEKPYECDICGKTFSNSSGLRVHK 240
Cdd:COG5189  346 DGKPYKCPveGCNKKYKNQNGLKYHMLhghqnqklhenpspekmniFSAKDKPYRCEVCDKRYKNLNGLKYHR 418
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 133-212 1.24e-04

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 45.48  E-value: 1.24e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966950428 133 GEKPYACE--ECGKAYMSYSSLINHKsthsgekncKCDECGKSFNYSSVLDQHKRIHTGEKPYECGECGKAFRNSSGLRV 210
Cdd:COG5189  346 DGKPYKCPveGCNKKYKNQNGLKYHM---------LHGHQNQKLHENPSPEKMNIFSAKDKPYRCEVCDKRYKNLNGLKY 416


                 ..
gi 966950428 211 HK 212
Cdd:COG5189  417 HR 418
SUF4-like cd20908
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
 443-491 3.37e-04

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 39.85  E-value: 3.37e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*....
gi 966950428 443 KPYkCSYCEKSFNYSSALEQHKRIHTrekpFGCDECGKAFRNNSGLKVH 491
Cdd:cd20908    1 KPW-CYYCDREFDDEKILIQHQKAKH----FKCHICHKKLYTAGGLAVH 44
zf-H2C2_2 pfam13465
Zinc-finger double domain;
236-260 3.96e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 38.12  E-value: 3.96e-04
                          10        20
                  ....*....|....*....|....*
gi 966950428  236 LRVHKRIHTGEKPYECDECGKAFIT 260
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
208-232 7.56e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 37.35  E-value: 7.56e-04
                          10        20
                  ....*....|....*....|....*
gi 966950428  208 LRVHKRIHTGEKPYECDICGKTFSN 232
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
320-344 1.04e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.97  E-value: 1.04e-03
                          10        20
                  ....*....|....*....|....*
gi 966950428  320 LIVHKRIHTGEKPYKCDVCGKAFSY 344
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 552-604 1.26e-03

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 42.01  E-value: 1.26e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 966950428 552 LGEKPYKCDV--CEKSFNYTSLLSQHKR-------------------VHTREKPYECDRCEKVFRNNSSLKVHK 604
Cdd:COG5189  345 KDGKPYKCPVegCNKKYKNQNGLKYHMLhghqnqklhenpspekmniFSAKDKPYRCEVCDKRYKNLNGLKYHR 418
zf-H2C2_2 pfam13465
Zinc-finger double domain;
180-204 1.36e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.58  E-value: 1.36e-03
                          10        20
                  ....*....|....*....|....*
gi 966950428  180 LDQHKRIHTGEKPYECGECGKAFRN 204
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
599-624 1.50e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.58  E-value: 1.50e-03
                          10        20
                  ....*....|....*....|....*.
gi 966950428  599 SLKVHKRIHTGEKPYECDVCGKAYIS 624
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
767-790 1.50e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.58  E-value: 1.50e-03
                          10        20
                  ....*....|....*....|....
gi 966950428  767 LDQHKRIHTGRKPYRCNECGKAFN 790
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFK 25
zf-H2C2_2 pfam13465
Zinc-finger double domain;
488-512 2.43e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.20  E-value: 2.43e-03
                          10        20
                  ....*....|....*....|....*
gi 966950428  488 LKVHKRIHTGERPYKCEECGKAYIS 512
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
123-146 4.10e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.42  E-value: 4.10e-03
                          10        20
                  ....*....|....*....|....
gi 966950428  123 SLRVHKRIHTGEKPYACEECGKAY 146
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSF 24
zf-H2C2_2 pfam13465
Zinc-finger double domain;
712-736 5.50e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.04  E-value: 5.50e-03
                          10        20
                  ....*....|....*....|....*
gi 966950428  712 LTVHKRIHTGEKPYECDECGKAYIS 736
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
SUF4-like cd20908
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
 303-351 6.49e-03

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 36.38  E-value: 6.49e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*....
gi 966950428 303 KPYeCDECGKAFRNSSGLIVHKRIHTgekpYKCDVCGKAFSYSSGLAVH 351
Cdd:cd20908    1 KPW-CYYCDREFDDEKILIQHQKAKH----FKCHICHKKLYTAGGLAVH 44
zf-H2C2_2 pfam13465
Zinc-finger double domain;
292-316 6.76e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 34.65  E-value: 6.76e-03
                          10        20
                  ....*....|....*....|....*
gi 966950428  292 LIQHKVIHTGEKPYECDECGKAFRN 316
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
404-428 7.03e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 34.65  E-value: 7.03e-03
                          10        20
                  ....*....|....*....|....*
gi 966950428  404 LKVHRRLHTGEKPYKCDVCGKAYIS 428
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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